Page last updated: 2024-09-05

lapatinib and posaconazole

lapatinib has been researched along with posaconazole in 2 studies

Compound Research Comparison

Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010)
(lapatinib)
Studies
(posaconazole)
Trials
(posaconazole)
Recent Studies (post-2010) (posaconazole)
1,9193051,4421,5751031,014

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)posaconazole (IC50)
Bile salt export pumpHomo sapiens (human)8.1
Steroid 17-alpha-hydroxylase/17,20 lyaseHomo sapiens (human)0.921
Cytochrome P450 3A4Homo sapiens (human)0.2458
AromataseHomo sapiens (human)8.4
Cytochrome P450 2C9 Homo sapiens (human)7.2
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.31
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.021
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.464
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1

Reviews

2 review(s) available for lapatinib and posaconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022