Compounds > lapatinib
Page last updated: 2024-09-05

lapatinib and pd 166285

lapatinib has been researched along with pd 166285 in 3 studies

Compound Research Comparison

Studies
(lapatinib)		Trials
(lapatinib)		Recent Studies (post-2010)
(lapatinib)		Studies
(pd 166285)		Trials
(pd 166285)		Recent Studies (post-2010) (pd 166285)
1,9193051,44226016

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)pd 166285 (IC50)
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.013
Hexose transporter 1 Plasmodium falciparum (malaria parasite P. falciparum)4.496
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)0.009
Epidermal growth factor receptorHomo sapiens (human)0.1042
Neuronal proto-oncogene tyrosine-protein kinase Src Mus musculus (house mouse)0.009
Platelet-derived growth factor receptor betaMus musculus (house mouse)0.067
Cyclin-dependent kinase 1Homo sapiens (human)0.1
Platelet-derived growth factor receptor betaHomo sapiens (human)0.0508
Solute carrier family 2, facilitated glucose transporter member 1Homo sapiens (human)9.992
Fibroblast growth factor receptor 1Homo sapiens (human)0.0487
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.0461
Fibroblast growth factor receptor 1Mus musculus (house mouse)0.043
Platelet-derived growth factor receptor alphaRattus norvegicus (Norway rat)0.0055
Fibroblast growth factor receptor 2Homo sapiens (human)0.044
Fibroblast growth factor receptor 2Mus musculus (house mouse)0.043
Fibroblast growth factor receptor 4Homo sapiens (human)0.044
Fibroblast growth factor receptor 3Homo sapiens (human)0.044
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)0.0589
Wee1-like protein kinaseHomo sapiens (human)0.0945
D(2) dopamine receptorRattus norvegicus (Norway rat)0.079
Myelin transcription factor 1Homo sapiens (human)0.0072
Fibroblast growth factor receptor 4Mus musculus (house mouse)0.043
Activin receptor type-1Homo sapiens (human)0.021
Platelet-derived growth factor receptor betaRattus norvegicus (Norway rat)0.0055
Fibroblast growth factor receptor 3Mus musculus (house mouse)0.043
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseHomo sapiens (human)0.017
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)0.037
calcium-dependent protein kinase 1Plasmodium falciparum 3D70.78
protein kinase 6Plasmodium falciparum 3D70.35

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Al-Mazaideh, GM; Erdmann, F; Göllner, C; Rohe, A; Schmidt, M; Sippl, W; Wichapong, K1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

3 other study(ies) available for lapatinib and pd 166285

ArticleYear
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay.
    European journal of medicinal chemistry, 2013, Volume: 61

    Topics: Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; Glycolipids; Humans; Membrane Proteins; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship

2013
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013