lapatinib has been researched along with norethindrone in 3 studies
| Studies (lapatinib) | Trials (lapatinib) | Recent Studies (post-2010) (lapatinib) | Studies (norethindrone) | Trials (norethindrone) | Recent Studies (post-2010) (norethindrone) |
|---|---|---|---|---|---|
| 1,919 | 305 | 1,442 | 4,295 | 884 | 303 |
| Protein | Taxonomy | lapatinib (IC50) | norethindrone (IC50) |
|---|---|---|---|
| Estrogen receptor | Homo sapiens (human) | 0.808 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.433 | |
| Progesterone receptor | Homo sapiens (human) | 0.0032 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.433 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.0711 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.433 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.433 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.433 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 4.537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
3 other study(ies) available for lapatinib and norethindrone
| Article | Year |
|---|---|
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |