Page last updated: 2024-09-05

lapatinib and nisoldipine

lapatinib has been researched along with nisoldipine in 3 studies

Compound Research Comparison

Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010)
(lapatinib)
Studies
(nisoldipine)
Trials
(nisoldipine)
Recent Studies (post-2010) (nisoldipine)
1,9193051,44280316851

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)nisoldipine (IC50)
Cytochrome P450 1A2Homo sapiens (human)1
Adenosine receptor A3Homo sapiens (human)7.12
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.12
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.003
Adenosine receptor A2aHomo sapiens (human)4.058
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.12
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.003

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ekins, S; Williams, AJ; Xu, JJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for lapatinib and nisoldipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for lapatinib and nisoldipine

ArticleYear
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014