Page last updated: 2024-09-05

lapatinib and moxifloxacin

lapatinib has been researched along with moxifloxacin in 3 studies

Compound Research Comparison

Studies (lapatinib)	Trials (lapatinib)	Recent Studies (post-2010) (lapatinib)	Studies (moxifloxacin)	Trials (moxifloxacin)	Recent Studies (post-2010) (moxifloxacin)
1,919	305	1,442	3,157	552	1,690

Protein Interaction Comparison

Protein	Taxonomy	moxifloxacin (IC50)
DNA gyrase subunit B	Staphylococcus aureus	5.1033
DNA gyrase subunit A	Escherichia coli K-12	1.4
DNA gyrase subunit B	Escherichia coli K-12	1.4
DNA topoisomerase 4 subunit A	Staphylococcus aureus	0.8
DNA gyrase subunit A	Staphylococcus aureus	7.25
DNA gyrase subunit B	Mycobacterium tuberculosis H37Rv	8.525
DNA gyrase subunit A	Mycobacterium tuberculosis H37Rv	8.66

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Takai, N; Tanaka, Y	1

Reviews

1 review(s) available for lapatinib and moxifloxacin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

2 other study(ies) available for lapatinib and moxifloxacin

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Imaging of drug and metabolite distribution by MS: case studies. Bioanalysis, 2015, Volume: 7, Issue:20 Topics: Animals; Autoradiography; Dogs; Fluoroquinolones; Lapatinib; Liver; Lung; Mice; Moxifloxacin; Pharmaceutical Preparations; Quinazolines; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Terfenadine; Tissue Distribution; Whole Body Imaging	2015

Article

Year

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012

Imaging of drug and metabolite distribution by MS: case studies.

Bioanalysis, 2015, Volume: 7, Issue:20

Topics: Animals; Autoradiography; Dogs; Fluoroquinolones; Lapatinib; Liver; Lung; Mice; Moxifloxacin; Pharmaceutical Preparations; Quinazolines; Rabbits; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Terfenadine; Tissue Distribution; Whole Body Imaging

2015