lapatinib has been researched along with methysergide in 4 studies
| Studies (lapatinib) | Trials (lapatinib) | Recent Studies (post-2010) (lapatinib) | Studies (methysergide) | Trials (methysergide) | Recent Studies (post-2010) (methysergide) |
|---|---|---|---|---|---|
| 1,919 | 305 | 1,442 | 2,935 | 81 | 80 |
| Protein | Taxonomy | lapatinib (IC50) | methysergide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.0021 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 1.631 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.807 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 4.763 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.054 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.943 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.013 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.0021 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.054 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.172 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.0006 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.162 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
4 other study(ies) available for lapatinib and methysergide
| Article | Year |
|---|---|
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |