Page last updated: 2024-09-05

lapatinib and methyl-thiohydantoin-tryptophan

lapatinib has been researched along with methyl-thiohydantoin-tryptophan in 2 studies

Compound Research Comparison

Studies (lapatinib)	Trials (lapatinib)	Recent Studies (post-2010) (lapatinib)	Studies (methyl-thiohydantoin-tryptophan)	Trials (methyl-thiohydantoin-tryptophan)	Recent Studies (post-2010) (methyl-thiohydantoin-tryptophan)
1,919	305	1,442	376	1	348

Protein Interaction Comparison

Protein	Taxonomy	lapatinib (IC50)	methyl-thiohydantoin-tryptophan (IC50)
Indoleamine 2,3-dioxygenase 1	Homo sapiens (human)		0.11
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)		0.6937

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Chen, Y; Gibson, SB; Henson, ES; Ma, S	1

Other Studies

2 other study(ies) available for lapatinib and methyl-thiohydantoin-tryptophan

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells. Cell death & disease, 2016, 07-21, Volume: 7 Topics: Antineoplastic Agents; Cation Transport Proteins; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Drug Synergism; Female; Ferritins; Gene Expression Regulation; Humans; Imidazoles; Indoles; Iron; Iron Chelating Agents; Lapatinib; Lysosomes; MCF-7 Cells; Phenylenediamines; Protein Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Receptors, Transferrin; Signal Transduction; Spiro Compounds; Transcription Factors; Transferrin	2016

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells.

Cell death & disease, 2016, 07-21, Volume: 7

Topics: Antineoplastic Agents; Cation Transport Proteins; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Drug Synergism; Female; Ferritins; Gene Expression Regulation; Humans; Imidazoles; Indoles; Iron; Iron Chelating Agents; Lapatinib; Lysosomes; MCF-7 Cells; Phenylenediamines; Protein Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Receptors, Transferrin; Signal Transduction; Spiro Compounds; Transcription Factors; Transferrin

2016