Compounds > lapatinib
Page last updated: 2024-09-05

lapatinib and mepazine

lapatinib has been researched along with mepazine in 2 studies

Compound Research Comparison

Studies
(lapatinib)		Trials
(lapatinib)		Recent Studies (post-2010)
(lapatinib)		Studies
(mepazine)		Trials
(mepazine)		Recent Studies (post-2010) (mepazine)
1,9193051,442121014

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)mepazine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.495
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.877
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.565
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.137
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)1.456
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.079
Alpha-2B adrenergic receptorHomo sapiens (human)0.397
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.191
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.877
Alpha-1D adrenergic receptorHomo sapiens (human)0.137
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.385
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.495
Histamine H1 receptorHomo sapiens (human)0.027
D(3) dopamine receptorHomo sapiens (human)2.006
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.514
5-hydroxytryptamine receptor 6Homo sapiens (human)1.837
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.18
Mucosa-associated lymphoid tissue lymphoma translocation protein 1Homo sapiens (human)0.6933

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for lapatinib and mepazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for lapatinib and mepazine

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011