lapatinib has been researched along with lu 28-179 in 4 studies
| Studies (lapatinib) | Trials (lapatinib) | Recent Studies (post-2010) (lapatinib) | Studies (lu 28-179) | Trials (lu 28-179) | Recent Studies (post-2010) (lu 28-179) |
|---|---|---|---|---|---|
| 1,919 | 305 | 1,442 | 52 | 0 | 29 |
| Protein | Taxonomy | lapatinib (IC50) | lu 28-179 (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 2 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 2 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.33 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.33 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.33 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.8 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.017 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Gibson, SB; Henson, ES; Ma, S | 1 |
| Blankstein, AR; Chen, Y; Choquette, TR; Dielschneider, RF; Gibson, SB; Henson, ES; Ma, S; Xiao, W | 1 |
| Blankstein, AR; Gibson, SB; Konzelman, C; Villalpando-Rodriguez, GE | 1 |
| Cai, N; Cheng, K; Liang, H; Wen, J; Xiong, Y; Zhang, W; Zhang, Y; Zhu, J | 1 |
1 review(s) available for lapatinib and lu 28-179
| Article | Year |
|---|---|
The Molecular Mechanisms of Regulating Oxidative Stress-Induced Ferroptosis and Therapeutic Strategy in Tumors.
Topics: Acetaminophen; Antineoplastic Agents; Antioxidants; Apoptosis; Artemisinins; Auranofin; Cell Death; Cisplatin; Epigenesis, Genetic; Fatty Acids; Ferroptosis; Haloperidol; Humans; Indoles; Iron; Lapatinib; Mevalonic Acid; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Oxygen; Quinolines; Reactive Oxygen Species; Sorafenib; Spiro Compounds; Sulfasalazine; Trigonella | 2020 |
3 other study(ies) available for lapatinib and lu 28-179
| Article | Year |
|---|---|
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells.
Topics: Antineoplastic Agents; Cation Transport Proteins; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Drug Synergism; Female; Ferritins; Gene Expression Regulation; Humans; Imidazoles; Indoles; Iron; Iron Chelating Agents; Lapatinib; Lysosomes; MCF-7 Cells; Phenylenediamines; Protein Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Receptors, Transferrin; Signal Transduction; Spiro Compounds; Transcription Factors; Transferrin | 2016 |
Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Female; Ferritins; Humans; Indoles; Lapatinib; Quinazolines; Reactive Oxygen Species; Spiro Compounds | 2017 |
Lysosomal Destabilizing Drug Siramesine and the Dual Tyrosine Kinase Inhibitor Lapatinib Induce a Synergistic Ferroptosis through Reduced Heme Oxygenase-1 (HO-1) Levels.
Topics: Antineoplastic Agents; Ferroptosis; Heme Oxygenase-1; Humans; Indoles; Lapatinib; Spiro Compounds; Transfection | 2019 |