lapatinib has been researched along with lonafarnib in 1 studies
| Studies (lapatinib) | Trials (lapatinib) | Recent Studies (post-2010) (lapatinib) | Studies (lonafarnib) | Trials (lonafarnib) | Recent Studies (post-2010) (lonafarnib) |
|---|---|---|---|---|---|
| 1,919 | 305 | 1,442 | 224 | 34 | 90 |
| Protein | Taxonomy | lapatinib (IC50) | lonafarnib (IC50) |
|---|---|---|---|
| Chain A, Protein farnesyltransferase alpha subunit | Rattus norvegicus (Norway rat) | 0.0019 | |
| Chain B, Protein farnesyltransferase beta subunit | Rattus norvegicus (Norway rat) | 0.0019 | |
| GTPase HRas | Homo sapiens (human) | 0.07 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 2.7 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Bos taurus (cattle) | 0.0081 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | 0.1498 | |
| Protein farnesyltransferase subunit beta | Bos taurus (cattle) | 0.0081 | |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | 0.1498 | |
| Protein farnesyltransferase subunit beta | Rattus norvegicus (Norway rat) | 0.0019 | |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Rattus norvegicus (Norway rat) | 0.0019 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dowlati, A; Halmos, B; Kern, JA; Kluge, A; Nethery, D | 1 |
1 other study(ies) available for lapatinib and lonafarnib
| Article | Year |
|---|---|
SCH66336, inhibitor of protein farnesylation, blocks signal transducer and activators of transcription 3 signaling in lung cancer and interacts with a small molecule inhibitor of epidermal growth factor receptor/human epidermal growth factor receptor 2.
Topics: Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Colorimetry; Drug Synergism; Flow Cytometry; Humans; Indicators and Reagents; Lapatinib; Mutation; Oncogene Protein v-akt; Piperidines; Prenylation; Pyridines; Quinazolines; Receptor, ErbB-2; Signal Transduction; STAT3 Transcription Factor | 2008 |