lapatinib has been researched along with isotretinoin in 4 studies
| Studies (lapatinib) | Trials (lapatinib) | Recent Studies (post-2010) (lapatinib) | Studies (isotretinoin) | Trials (isotretinoin) | Recent Studies (post-2010) (isotretinoin) |
|---|---|---|---|---|---|
| 1,919 | 305 | 1,442 | 4,064 | 506 | 1,216 |
| Protein | Taxonomy | lapatinib (IC50) | isotretinoin (IC50) |
|---|---|---|---|
| Adenosine receptor A3 | Homo sapiens (human) | 4.169 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 4.169 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 6.612 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 0.462 | |
| Cellular retinoic acid-binding protein 1 | Gallus gallus (chicken) | 0.9 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.848 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 4.169 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 2.529 | |
| Olfactory receptor 51E2 | Homo sapiens (human) | 0.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for lapatinib and isotretinoin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for lapatinib and isotretinoin
| Article | Year |
|---|---|
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |