lapatinib has been researched along with gdc 0449 in 2 studies
Studies (lapatinib) | Trials (lapatinib) | Recent Studies (post-2010) (lapatinib) | Studies (gdc 0449) | Trials (gdc 0449) | Recent Studies (post-2010) (gdc 0449) |
---|---|---|---|---|---|
1,919 | 305 | 1,442 | 666 | 68 | 611 |
Protein | Taxonomy | lapatinib (IC50) | gdc 0449 (IC50) |
---|---|---|---|
Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.02 | |
Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.02 | |
Smoothened homolog | Mus musculus (house mouse) | 0.07 | |
Sonic hedgehog protein | Homo sapiens (human) | 0.8825 | |
Sonic hedgehog protein | Mus musculus (house mouse) | 0.0077 | |
Smoothened homolog | Homo sapiens (human) | 0.0222 | |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.4 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 1 (50.00) | 2.80 |
Authors | Studies |
---|---|
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
1 review(s) available for lapatinib and gdc 0449
Article | Year |
---|---|
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
1 other study(ies) available for lapatinib and gdc 0449
Article | Year |
---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |