Page last updated: 2024-09-05

lapatinib and doxorubicin hydrochloride

lapatinib has been researched along with doxorubicin hydrochloride in 2 studies

Compound Research Comparison

Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010)
(lapatinib)
Studies
(doxorubicin hydrochloride)
Trials
(doxorubicin hydrochloride)
Recent Studies (post-2010) (doxorubicin hydrochloride)
1,9193051,4422770205

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)doxorubicin hydrochloride (IC50)
RNA polymerase beta subunit (EC 2.7.7.6), partialEscherichia coli14.3747
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)0.266
Apoptotic peptidase activating factor 1Homo sapiens (human)21.2
TPA: protein transporter TIM23Saccharomyces cerevisiae S288C12.7
caspase-9 isoform alpha precursorHomo sapiens (human)34.6
caspase-3 isoform a preproproteinHomo sapiens (human)34.6
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)0.266
14-3-3 protein gammaHomo sapiens (human)0.7812
DNA topoisomerase 2-alphaHomo sapiens (human)0.94

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Ekins, S; Williams, AJ; Xu, JJ1
Cai, Z; Ghaleb, H; Huang, W; Jiang, Y; Liu, Y; Qian, H; Qiu, Q; Shi, W; Yin, Z; Zhang, P; Zhou, J; Zou, F1

Other Studies

2 other study(ies) available for lapatinib and doxorubicin hydrochloride

ArticleYear
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Exploration of novel phthalazinone derivatives as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel.
    European journal of medicinal chemistry, 2022, Apr-05, Volume: 233

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel

2022