Page last updated: 2024-09-05

lapatinib and dihydroergotamine

lapatinib has been researched along with dihydroergotamine in 2 studies

Compound Research Comparison

Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010)
(lapatinib)
Studies
(dihydroergotamine)
Trials
(dihydroergotamine)
Recent Studies (post-2010) (dihydroergotamine)
1,9193051,4421,450241116

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)dihydroergotamine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.09
Cytochrome P450 3A4Homo sapiens (human)3.9996
Alpha-2A adrenergic receptorHomo sapiens (human)0.001
D(2) dopamine receptorHomo sapiens (human)0.0089
Alpha-2B adrenergic receptorHomo sapiens (human)0.0039
Alpha-2C adrenergic receptorHomo sapiens (human)0.01
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0007
D(1A) dopamine receptorHomo sapiens (human)2.395
Alpha-1D adrenergic receptorHomo sapiens (human)0.029
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.008
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.09
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0007
D(3) dopamine receptorHomo sapiens (human)0.0053
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0068
5-hydroxytryptamine receptor 6Homo sapiens (human)0.0032
Multidrug and toxin extrusion protein 1Homo sapiens (human)2.8

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for lapatinib and dihydroergotamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

1 other study(ies) available for lapatinib and dihydroergotamine

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011