Page last updated: 2024-09-05

lapatinib and deferoxamine

lapatinib has been researched along with deferoxamine in 4 studies

Compound Research Comparison

Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010)
(lapatinib)
Studies
(deferoxamine)
Trials
(deferoxamine)
Recent Studies (post-2010) (deferoxamine)
1,9193051,4426,7032401,266

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)deferoxamine (IC50)
Lysine-specific demethylase 4AHomo sapiens (human)3.275
Deoxyhypusine hydroxylaseHomo sapiens (human)5

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Chen, Y; Gibson, SB; Henson, ES; Ma, S1

Reviews

1 review(s) available for lapatinib and deferoxamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for lapatinib and deferoxamine

ArticleYear
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells.
    Cell death & disease, 2016, 07-21, Volume: 7

    Topics: Antineoplastic Agents; Cation Transport Proteins; Cell Death; Cell Line, Tumor; Cyclohexylamines; Deferoxamine; Drug Synergism; Female; Ferritins; Gene Expression Regulation; Humans; Imidazoles; Indoles; Iron; Iron Chelating Agents; Lapatinib; Lysosomes; MCF-7 Cells; Phenylenediamines; Protein Kinase Inhibitors; Quinazolines; Reactive Oxygen Species; Receptors, Transferrin; Signal Transduction; Spiro Compounds; Transcription Factors; Transferrin

2016