Page last updated: 2024-09-05

lapatinib and celastrol

lapatinib has been researched along with celastrol in 1 studies

Compound Research Comparison

Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010)
(lapatinib)
Studies
(celastrol)
Trials
(celastrol)
Recent Studies (post-2010) (celastrol)
1,9193051,4428851741

Protein Interaction Comparison

ProteinTaxonomylapatinib (IC50)celastrol (IC50)
Telomerase reverse transcriptaseHomo sapiens (human)0.78
Ubiquitin carboxyl-terminal hydrolase 2Homo sapiens (human)6.8
Ubiquitin carboxyl-terminal hydrolase isozyme L1Homo sapiens (human)6.8
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)8.41
Ubiquitin carboxyl-terminal hydrolase isozyme L3Homo sapiens (human)6.8
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)3.45
Tyrosine-protein phosphatase non-receptor type 6Homo sapiens (human)3.1
Tyrosine-protein phosphatase non-receptor type 11Homo sapiens (human)3.5667
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.25
Regulator of G-protein signaling 17Homo sapiens (human)6.1795
Ubiquitin carboxyl-terminal hydrolase 15Homo sapiens (human)6.8
Ubiquitin carboxyl-terminal hydrolase isozyme L5Homo sapiens (human)6.8

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bailey, TA; Band, H; Band, V; Clubb, RJ; Duan, L; Natarajan, A; Nyong, AM; Ortega-Cava, C; Raja, SM; Reddi, AL; Williams, SH; Zhao, X1

Other Studies

1 other study(ies) available for lapatinib and celastrol

ArticleYear
Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.
    Cancer biology & therapy, 2011, Jan-15, Volume: 11, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Female; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Lapatinib; Mice; Mice, SCID; Pentacyclic Triterpenes; Quinazolines; Receptor, ErbB-2; Signal Transduction; Trastuzumab; Triterpenes; Tumor Burden; Xenograft Model Antitumor Assays

2011