Page last updated: 2024-09-05

lapatinib and N-(3-ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine

lapatinib has been researched along with N-(3-ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine in 2 studies

Compound Research Comparison

Studies (lapatinib)	Trials (lapatinib)	Recent Studies (post-2010) (lapatinib)	Studies (N-(3-ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine)	Trials (N-(3-ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine)	Recent Studies (post-2010) (N-(3-ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine)
1,919	305	1,442	11	0	7

Protein Interaction Comparison

Protein	Taxonomy	N-(3-ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine (IC50)
Cyclin-G-associated kinase	Homo sapiens (human)	0.072
Epidermal growth factor receptor	Homo sapiens (human)	0.038
Fructose-1,6-bisphosphatase 1	Sus scrofa (pig)	1.6
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	0.0705
Fructose-1,6-bisphosphatase 1	Homo sapiens (human)	0.9
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	0.0705
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	0.0705
Histamine H3 receptor	Rattus norvegicus (Norway rat)	0.9

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Asquith, CRM; Drewry, DH; East, MP; Havener, TM; Johnson, GL; Laitinen, T; Morris, DC; Naegeli, KM; Wells, CI; Zuercher, WJ	1
Asquith, CRM; Crona, DJ; Fleck, N; Grundner, C; Torrice, CD; Zuercher, WJ	1

Other Studies

2 other study(ies) available for lapatinib and N-(3-ethynylphenyl)-6,7-dimethoxy-4-quinazolinamine

Article	Year
Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma. Journal of medicinal chemistry, 2019, 05-09, Volume: 62, Issue:9 Topics: Aminoquinolines; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chordoma; Drug Design; ErbB Receptors; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Molecular Docking Simulation; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines	2019
Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines. Bioorganic & medicinal chemistry letters, 2019, 09-15, Volume: 29, Issue:18 Topics: Aniline Compounds; Antitubercular Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Quinazolines; Quinolines; Structure-Activity Relationship	2019

Article

Year

Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma.

Journal of medicinal chemistry, 2019, 05-09, Volume: 62, Issue:9

Topics: Aminoquinolines; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chordoma; Drug Design; ErbB Receptors; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Molecular Docking Simulation; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Quinazolines

2019

Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines.

Bioorganic & medicinal chemistry letters, 2019, 09-15, Volume: 29, Issue:18

Topics: Aniline Compounds; Antitubercular Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Quinazolines; Quinolines; Structure-Activity Relationship

2019