Compounds > lapachol

lapachol and norlapachol

lapachol has been researched along with norlapachol in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Campillo, M; Díaz-Peñate, RG; Estévez-Braun, A; García-Castellano, JM; Pardo, L; Pérez-Sacau, E; Ravelo, AG1
Andrade, CK; da Silva Júnior, EN; de Assis Lopes, F; de Castro, SL; de Simone, CA; de Souza, MC; Fernandes, MC; Ferreira, VF; Menna-Barreto, RF; Pinto, AV; Pinto, Mdo C1
Andrade, CK; Cavalcanti, BC; da Silva, EN; de Castro, SL; de Simone, CA; Goulart, MO; Guimarães, TT; Menna-Barreto, RF; Pessoa, C; Pinto, AV; Pinto, Mdo C; Sabino, JR1
Carneiro, PF; Cavalcanti, BC; Coelho, TS; da Silva Júnior, EN; da Silva, PA; de Almeida, RG; de Moura, KC; de Oliveira, NM; de Simone, CA; Nunes, IK; Pessoa, C; Pinto, AV; Pinto, Mdo C1
Camara, CA; da Silva, EN; de Melo, IM; de Oliveira, RN; Diogo, EB; do Monte-Neto, RL; Ferreira, VF; Frézard, F; Guimarães, TT; Lanza, JS; Melo, MN; Pinto, Mdo C; Valença, WO1
Câmara, CA; Coutinho, HDM; de Farias, PAM; de Morais Oliveira-Tintino, CD; Figueredo, FG; Fonteles, MMF; Menezes, IRA; Paz, JA; Ramos, ITL; Silva, TMS; Tintino, SR1
Camara, CA; Cavalcante-Figueredo, MR; Coutinho, HDM; da Silva, RLP; de Morais Oliveira-Tintino, CD; Ferreira Matias, EF; Figueiredo, JG; Figueredo, FG; Fonteles, MMF; Parente, RELT; Silva, TMS; Tintino, SR1

Other Studies

7 other study(ies) available for lapachol and norlapachol

ArticleYear
Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Furans; HL-60 Cells; Humans; Models, Molecular; Naphthoquinones; Phenanthrenes; Pyrans; Structure-Activity Relationship

2007
Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones.
    Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9

    Topics: Animals; Antiprotozoal Agents; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Naphthoquinones; Parasitic Sensitivity Tests; Stereoisomerism; Trypanosoma cruzi

2008
The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.
    Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9

    Topics: Animals; Anthraquinones; Antiparasitic Agents; Crystallography, X-Ray; Imidazoles; Mice; Molecular Structure; Naphthoquinones; Parasitic Sensitivity Tests; Quinones; Triazoles; Trypanosoma cruzi

2010
Quinonoid and phenazine compounds: synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antitubercular Agents; Cells, Cultured; Drug Resistance, Microbial; Isoniazid; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium tuberculosis; Phenazines; Quinones; Rifampin; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; X-Ray Diffraction

2011
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Alkynes; Animals; Antimony; Antiprotozoal Agents; Azides; Catalysis; Cell Survival; Cells, Cultured; Copper; Cycloaddition Reaction; Drug Resistance; Leishmania; Leishmania infantum; Macrophages, Peritoneal; Mice; Naphthoquinones; Parasitic Sensitivity Tests; Species Specificity; Triazoles

2013
Effect of hydroxyamines derived from lapachol and norlachol against Staphylococcus aureus strains carrying the NorA efflux pump.
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2020, Volume: 84

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Computer Simulation; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Molecular Docking Simulation; Multidrug Resistance-Associated Proteins; Naphthoquinones; Norfloxacin; Staphylococcus aureus

2020
Inhibition of Staphylococcus aureus TetK and MsrA efflux pumps by hydroxyamines derived from lapachol and norlachol.
    Journal of bioenergetics and biomembranes, 2021, Volume: 53, Issue:2

    Topics: Anti-Bacterial Agents; Naphthoquinones; Staphylococcus aureus

2021