lapachol has been researched along with beta-lapachone in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 10 (41.67) | 24.3611 |
| 2020's | 4 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, K; Sellmer, A; Wiegrebe, W | 1 |
| Carvalho, LH; da Silva Filho, JF; da Silva, MJ; de Andrade-Neto, VF; Goulart, MO; Krettli, AU; Pinto, AV; Pinto, Mdo C; Zalis, MG | 1 |
| Campillo, M; Díaz-Peñate, RG; Estévez-Braun, A; García-Castellano, JM; Pardo, L; Pérez-Sacau, E; Ravelo, AG | 1 |
| Iida, A; Kaneko, M; Nishimura, K; Tokuda, H; Yamashita, M | 1 |
| Armstrong, V; Ciudad, K; Ferreira, J; Kemmerling, U; Maya, JD; Morello, A; Orellana, M; Salas, C; Tapia, RA | 1 |
| Baskaran, S; Eyong, KO; Folefoc, GN; Kuete, V; Kumar, PS; Nkengfack, EA | 1 |
| Iida, A; Kaneko, M; Kumeda, Y; Nishimura, K; Tokuda, H; Yamashita, M | 1 |
| Bonifazi, EL; Burton, G; León, LG; Misico, RI; Padrón, JM; Ríos-Luci, C | 1 |
| Andrade, CK; Cavalcanti, BC; da Silva, EN; de Castro, SL; de Simone, CA; Goulart, MO; Guimarães, TT; Menna-Barreto, RF; Pessoa, C; Pinto, AV; Pinto, Mdo C; Sabino, JR | 1 |
| Camara, CA; Costa, VA; da Silva Júnior, EN; de Araujo, AS; de Castro, SL; de Melo, IM; de Oliveira, RN; de Simone, CA; de Souza Filho, JD; Diogo, EB; dos Santos, MR; Emery, FS; Menna-Barreto, RF; Valença, WO | 1 |
| Bonifazi, EL; Burton, G; León, LG; Misico, RI; Montero, JC; Padrón, JM; Pandiella, A; Ríos-Luci, C | 1 |
| Caira, MR; da Silva Júnior, EN; Davies-Coleman, MT; de la Mare, JA; Edkins, AL; Hendricks, DT; Osoniyi, O; Pinto, AV; Shunmoogam-Gounden, N; Sunassee, SN; Veale, CG | 1 |
| Camara, CA; da Silva, EN; de Melo, IM; de Oliveira, RN; Diogo, EB; do Monte-Neto, RL; Ferreira, VF; Frézard, F; Guimarães, TT; Lanza, JS; Melo, MN; Pinto, Mdo C; Valença, WO | 1 |
| Clamor, C; Löcken, H; Müller, K | 1 |
| Abdeen, S; Chapman, E; Chitre, S; Hoang, QQ; Johnson, SM; Park, Y; Ray, AM; Salim, N; Sivinski, J; Stevens, M; Washburn, A | 1 |
| Ihara, M; Iida, A; Nagai, S; Sagara, M; Saito, K; Tahara, T; Watanabe, A; Yamano, Y; Yamashita, M; Yutani, M | 1 |
| Beteck, RM; Legoabe, LJ; Patel, OPS | 1 |
| Campos-Takaki, GM; Guiraud, P; Seigle-Murandi, F; Simeon de Buochberg, M; Steiman, R | 1 |
| Estévez-Braun, A; Giménez Turba, A; Gutiérrez Yapu, D; Pérez-Sacau, E; Ravelo, AG | 1 |
| Brum, TB; Leitão, GG; Lobato, AP; Pinto, AV; Pinto, Mdo C; Silva, RS | 1 |
| Inagaki, R; Koketsu, M; Ninomiya, M; Tanaka, K | 1 |
| Green, IR; Hussain, H | 1 |
| Araújo, CRM; da Costa, MM; de Oliveira, HP; Dos Anjos Santos, VL; Fernandes, AWC | 1 |
| Brustolin, AÁ; Caetano, W; Campanholi, KSS; Demarchi, IG; Lera-Nonose, DSSL; Lonardoni, MVC; Oyama, J; Ramos-Milaré, ÁCFH; Silva, EL; Silveira, TGV; Sydor, BG | 1 |
2 review(s) available for lapachol and beta-lapachone
| Article | Year |
|---|---|
Antimalarial application of quinones: A recent update.
Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinones; Structure-Activity Relationship | 2021 |
Lapachol and lapachone analogs: a journey of two decades of patent research(1997-2016).
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Design; Humans; Naphthoquinones; Neoplasms; Patents as Topic; Tabebuia | 2017 |
22 other study(ies) available for lapachol and beta-lapachone
| Article | Year |
|---|---|
Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Cell Division; Cell Line; Humans; Keratinocytes; Keratolytic Agents; L-Lactate Dehydrogenase; Naphthoquinones; Psoriasis; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1999 |
Antimalarial activity of phenazines from lapachol, beta-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.
Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Malaria; Mice; Naphthoquinones; Phenazines; Plasmodium berghei; Plasmodium falciparum | 2004 |
Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Furans; HL-60 Cells; Humans; Models, Molecular; Naphthoquinones; Phenanthrenes; Pyrans; Structure-Activity Relationship | 2007 |
Stereoselective synthesis and cytotoxicity of a cancer chemopreventive naphthoquinone from Tabebuia avellanedae.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Molecular Conformation; Naphthoquinones; Plant Extracts; Tabebuia | 2007 |
Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
Topics: Animals; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Stereoisomerism; Trypanocidal Agents; Trypanosoma cruzi | 2008 |
Semisynthesis and antitumoral activity of 2-acetylfuranonaphthoquinone and other naphthoquinone derivatives from lapachol.
Topics: Aldehydes; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Furans; Humans; Models, Chemical; Naphthoquinones; Neoplasms; Ozone; Plant Extracts; Quinones | 2008 |
Synthesis and evaluation of bioactive naphthoquinones from the Brazilian medicinal plant, Tabebuia avellanedae.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Mice; Microbial Sensitivity Tests; Naphthoquinones; Plants, Medicinal; Stereoisomerism; Tabebuia | 2009 |
Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Lipids; Magnetic Resonance Spectroscopy; Naphthoquinones; Prenylation; Structure-Activity Relationship | 2010 |
The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.
Topics: Animals; Anthraquinones; Antiparasitic Agents; Crystallography, X-Ray; Imidazoles; Mice; Molecular Structure; Naphthoquinones; Parasitic Sensitivity Tests; Quinones; Triazoles; Trypanosoma cruzi | 2010 |
On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
Topics: Animals; Chemistry Techniques, Synthetic; Click Chemistry; Drug Discovery; Mice; Naphthoquinones; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 2012 |
β-Lapachone analogs with enhanced antiproliferative activity.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases; Humans; Naphthoquinones; Reactive Oxygen Species; Topoisomerase Inhibitors | 2012 |
Cytotoxicity of lapachol, β-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Esophageal Neoplasms; Humans; Mice; Models, Molecular; Molecular Structure; Naphthoquinones; NIH 3T3 Cells; Structure-Activity Relationship | 2013 |
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Animals; Antimony; Antiprotozoal Agents; Azides; Catalysis; Cell Survival; Cells, Cultured; Copper; Cycloaddition Reaction; Drug Resistance; Leishmania; Leishmania infantum; Macrophages, Peritoneal; Mice; Naphthoquinones; Parasitic Sensitivity Tests; Species Specificity; Triazoles | 2013 |
Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Phosphorylation; Reactive Oxygen Species; STAT3 Transcription Factor | 2018 |
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
Topics: Biological Products; Chaperonin 10; Chaperonin 60; Escherichia coli; Humans; Inhibitory Concentration 50; Protein Folding; Rafoxanide; Salicylanilides; Suramin | 2019 |
STAT3 inhibitory activity of naphthoquinones isolated from Tabebuia avellanedae.
Topics: Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Naphthoquinones; STAT3 Transcription Factor; Structure-Activity Relationship; Tabebuia | 2020 |
Comparison of antibacterial and antifungal activities of lapachol and beta-lapachone.
Topics: Anti-Infective Agents; Antifungal Agents; Microbial Sensitivity Tests; Molecular Structure; Naphthoquinones | 1994 |
Antiplasmodial activity of naphthoquinones related to lapachol and beta-lapachone.
Topics: Animals; Antimalarials; Molecular Structure; Naphthoquinones; Plasmodium falciparum | 2005 |
Applications of counter-current chromatography in organic synthesis purification of heterocyclic derivatives of lapachol.
Topics: Activating Transcription Factor 6; Chromatography, Thin Layer; Countercurrent Distribution; Cyclization; Imidazoles; Molecular Structure; Naphthoquinones; Oxazoles; Quinoxalines | 2007 |
Synthesis, Characterization, and Antileukemic Properties of Naphthoquinone Derivatives of Lawsone.
Topics: Alkenes; Antineoplastic Agents; Cell Proliferation; Crystallography, X-Ray; Dimerization; Glutathione; HL-60 Cells; Humans; Molecular Conformation; Naphthoquinones; Structure-Activity Relationship | 2015 |
Anti-biofilm Effect of β-Lapachone and Lapachol Oxime Against Isolates of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Biofilms; Blood Culture; Microbial Sensitivity Tests; Naphthoquinones; Oximes; Staphylococcus aureus | 2020 |
In vitro effects of lapachol and β-lapachone against Leishmania amazonensis.
Topics: Animals; Antiprotozoal Agents; Humans; Leishmania mexicana; Mice; Mice, Inbred BALB C; Naphthoquinones | 2023 |