Compounds > lapachol

lapachol and atovaquone

lapachol has been researched along with atovaquone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (50.00)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Arantes, LM; Braga de Oliveira, A; Brandão, GC; Doerksen, RJ; Pereira, GR; Rocha Missias, FC; Roy, KK; Soares, LF1
Calil, FA; Castilho, MS; Chiappetta, ERC; David, JS; Emery, FS; Fumagalli, F; Leite, FHA; Mello, RB; Nonato, MC1
Beteck, RM; Legoabe, LJ; Patel, OPS1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Goswami, D; Gurule, S; Khuroo, AH; Monif, T1
Borgati, TF; de Oliveira, AB; de Souza, LCR; do Nascimento, MFA; Tagliati, CA1

Reviews

1 review(s) available for lapachol and atovaquone

ArticleYear
Antimalarial application of quinones: A recent update.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinones; Structure-Activity Relationship

2021

Other Studies

5 other study(ies) available for lapachol and atovaquone

ArticleYear
Antimalarial naphthoquinones. Synthesis via click chemistry, in vitro activity, docking to PfDHODH and SAR of lapachol-based compounds.
    European journal of medicinal chemistry, 2018, Feb-10, Volume: 145

    Topics: Antimalarials; Cell Survival; Chloroquine; Click Chemistry; Dose-Response Relationship, Drug; Drug Resistance; Hep G2 Cells; Humans; Models, Molecular; Molecular Structure; Naphthoquinones; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2018
Ligand-based design, synthesis and biochemical evaluation of potent and selective inhibitors of Schistosoma mansoni dihydroorotate dehydrogenase.
    European journal of medicinal chemistry, 2019, Apr-01, Volume: 167

    Topics: Animals; Anthelmintics; Dihydroorotate Dehydrogenase; Drug Design; Humans; Ligands; Oxidoreductases Acting on CH-CH Group Donors; Quinones; Schistosoma mansoni; Schistosomiasis mansoni; Structure-Activity Relationship

2019
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
LC-APCI mass spectrometric method development and validation for the determination of atovaquone in human plasma.
    Biomedical chromatography : BMC, 2010, Volume: 24, Issue:5

    Topics: Anti-Infective Agents; Atovaquone; Chromatography, Liquid; Humans; Naphthoquinones; Reference Standards; Sensitivity and Specificity; Tandem Mass Spectrometry

2010
In silico, in vitro and in vivo evaluation of natural Bignoniaceous naphthoquinones in comparison with atovaquone targeting the selection of potential antimalarial candidates.
    Toxicology and applied pharmacology, 2020, 08-15, Volume: 401

    Topics: A549 Cells; Animals; Antimalarials; Atovaquone; Caco-2 Cells; Computer Simulation; Dogs; Drug Delivery Systems; Drug Evaluation, Preclinical; Female; Hep G2 Cells; Humans; LLC-PK1 Cells; Madin Darby Canine Kidney Cells; Mice; Naphthoquinones; Plasmodium falciparum; Swine

2020