lansoprazole and tacrolimus

lansoprazole has been researched along with tacrolimus in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (60.87)29.6817
2010's8 (34.78)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Fukao, K; Homma, M; Itagaki, F; Kohda, Y; Yuzawa, K2
Inui, K; Ito, N; Motohashi, H; Ogawa, O; Okuda, M; Takahashi, K; Yamamoto, S; Yonezawa, A1
Homma, M; Itagaki, F; Kohda, Y; Naito, S; Nishimura, M; Ohkohchi, N; Ueda, N; Yuzawa, K1
Habuchi, T; Kagaya, H; Miura, M; Sagae, Y; Satoh, S; Suzuki, T; Tada, H1
Habuchi, T; Inoue, K; Ishikawa, M; Kagaya, H; Kanno, S; Miura, M; Sagae, Y; Saito, M; Satoh, S; Suzuki, T; Tada, H1
Habuchi, T; Inoue, K; Itoh, Y; Kagaya, H; Miura, M; Satoh, S; Suzuki, T; Tada, H; Tanaka, Y1
Habuchi, T; Inoue, K; Kagaya, H; Miura, M; Sagae, Y; Satoh, S; Suzuki, T; Tada, H1
Habuchi, T; Inoue, K; Kagaya, H; Miura, M; Saito, M; Satoh, S; Suzuki, T1
Hosohata, K; Inui, K; Katsura, T; Masuda, S; Ogura, Y; Oike, F; Takada, Y; Uemoto, S1
Egawa, H; Hosohata, K; Inui, K; Kaido, T; Katsura, T; Masuda, S; Ogura, Y; Oike, F; Takada, Y; Uemoto, S1
Habuchi, T; Hayakari, M; Kagaya, H; Miura, M; Niioka, T; Saito, M; Satoh, S1
Fujieda, A; Iwamoto, T; Katayama, N; Monma, F; Nakatani, K; Okuda, M1
Hanafusa, T; Hata, K; Hirano-Kuwata, S; Isoda, K; Kotani, T; Makino, S; Shoda, T; Takeuchi, T; Yoshida, S1
Aydin, F; Caliskan, Y; Ciftci, HS; Demir, E; Karadeniz, MS; Nane, I; Oguz, FS; Tefik, T; Turkmen, A; Yazıcı, H1

Reviews

2 review(s) available for lansoprazole and tacrolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Trials

4 trial(s) available for lansoprazole and tacrolimus

ArticleYear
Effect of lansoprazole and rabeprazole on tacrolimus pharmacokinetics in healthy volunteers with CYP2C19 mutations.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cross-Over Studies; Cytochrome P-450 CYP2C19; Drug Interactions; Female; Genotype; Humans; Immunosuppressive Agents; Lansoprazole; Male; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Omeprazole; Rabeprazole; Tacrolimus

2004
Comparison of enantioselective disposition of rabeprazole versus lansoprazole in renal-transplant recipients who are CYP2C19 extensive metabolizers.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cytochrome P-450 CYP2C19; Dexlansoprazole; Humans; Immunosuppressive Agents; Kidney Transplantation; Kinetics; Lansoprazole; Mixed Function Oxygenases; Models, Molecular; Molecular Structure; Omeprazole; Rabeprazole; Stereoisomerism; Substrate Specificity; Tacrolimus

2005
Influence of ABCB1 C3435T polymorphism on the pharmacokinetics of lansoprazole and gastroesophageal symptoms in Japanese renal transplant recipients classified as CYP2C19 extensive metabolizers and treated with tacrolimus.
    International journal of clinical pharmacology and therapeutics, 2006, Volume: 44, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Alleles; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Asian People; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP2C19; Dexlansoprazole; Female; Gastroesophageal Reflux; Genotype; Half-Life; Humans; Immunosuppressive Agents; Japan; Kidney Transplantation; Lansoprazole; Male; Middle Aged; Mixed Function Oxygenases; Organic Anion Transporters; Polymorphism, Genetic; Tacrolimus

2006
Influence of rabeprazole and lansoprazole on the pharmacokinetics of tacrolimus in relation to CYP2C19, CYP3A5 and MDR1 polymorphisms in renal transplant recipients.
    Biopharmaceutics & drug disposition, 2007, Volume: 28, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Female; Genes, MDR; Humans; Immunosuppressive Agents; Kidney Transplantation; Lansoprazole; Male; Middle Aged; Mixed Function Oxygenases; Polymorphism, Genetic; Rabeprazole; Tacrolimus

2007

Other Studies

17 other study(ies) available for lansoprazole and tacrolimus

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of lansoprazole and rabeprazole on tacrolimus blood concentration: case of a renal transplant recipient with CYP2C19 gene mutation.
    Transplantation, 2002, Jan-27, Volume: 73, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Exons; Female; Humans; Immunosuppressive Agents; Lansoprazole; Middle Aged; Mixed Function Oxygenases; Mutation; Omeprazole; Proton Pump Inhibitors; Rabeprazole; Tacrolimus

2002
Drug interaction of tacrolimus and proton pump inhibitors in renal transplant recipients with CYP2C19 gene mutation.
    Transplantation proceedings, 2002, Volume: 34, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Cytochrome P-450 CYP2C19; Drug Interactions; Famotidine; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Lansoprazole; Male; Middle Aged; Mixed Function Oxygenases; Omeprazole; Proton Pump Inhibitors; Rabeprazole; Tacrolimus

2002
Lansoprazole-tacrolimus interaction in Japanese transplant recipient with CYP2C19 polymorphism.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Drug Synergism; Humans; Immunosuppressive Agents; Kidney Transplantation; Lansoprazole; Male; Mixed Function Oxygenases; Omeprazole; Polymorphism, Genetic; Tacrolimus

2004
Influence of cytochrome P450 (CYP) 3A5 polymorphisms on the pharmacokinetics of lansoprazole enantiomers in CYP2C19 extensive metaboliser renal transplant recipients.
    Clinical drug investigation, 2007, Volume: 27, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Infective Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Immunosuppressive Agents; Kidney Transplantation; Lansoprazole; Mixed Function Oxygenases; Mycophenolic Acid; Polymorphism, Genetic; Stereoisomerism; Tacrolimus

2007
Influence of lansoprazole and rabeprazole on mycophenolic acid pharmacokinetics one year after renal transplantation.
    Therapeutic drug monitoring, 2008, Volume: 30, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Drug Therapy, Combination; Female; Genotype; Humans; Immunosuppressive Agents; Kidney Transplantation; Lansoprazole; Male; Middle Aged; Mixed Function Oxygenases; Mycophenolic Acid; Polymorphism, Single Nucleotide; Prednisolone; Rabeprazole; Retrospective Studies; Tacrolimus

2008
Interaction between tacrolimus and lansoprazole, but not rabeprazole in living-donor liver transplant patients with defects of CYP2C19 and CYP3A5.
    Drug metabolism and pharmacokinetics, 2008, Volume: 23, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adjuvants, Immunologic; Adult; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Interactions; Female; Humans; Lansoprazole; Liver Transplantation; Living Donors; Male; Middle Aged; Mixed Function Oxygenases; Rabeprazole; Tacrolimus

2008
Impact of intestinal CYP2C19 genotypes on the interaction between tacrolimus and omeprazole, but not lansoprazole, in adult living-donor liver transplant patients.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Drug Interactions; Female; Genotype; Humans; Immunosuppressive Agents; Lansoprazole; Liver Transplantation; Living Donors; Male; Middle Aged; Omeprazole; Tacrolimus

2009
Pharmacogenetic determinants for interindividual difference of tacrolimus pharmacokinetics 1 year after renal transplantation.
    Journal of clinical pharmacy and therapeutics, 2011, Volume: 36, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Interactions; Female; Genotype; Humans; Immunosuppressive Agents; Kidney Transplantation; Lansoprazole; Male; Pharmacogenetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Rabeprazole; Tacrolimus; Time Factors

2011
Hepatic drug interaction between tacrolimus and lansoprazole in a bone marrow transplant patient receiving voriconazole and harboring CYP2C19 and CYP3A5 heterozygous mutations.
    Clinical therapeutics, 2011, Volume: 33, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Bone Marrow Transplantation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Infusions, Intravenous; Lansoprazole; Liver; Male; Mutation; Pyrimidines; Tacrolimus; Triazoles; Voriconazole

2011
The proton pump inhibitor lansoprazole, but not rabeprazole, the increased blood concentrations of calcineurin inhibitors in Japanese patients with connective tissue diseases.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:13

    Topics: Calcineurin Inhibitors; Connective Tissue Diseases; Cyclosporine; Cytochrome P-450 CYP2C19; Drug Interactions; Female; Gastrointestinal Diseases; Genotype; Humans; Lansoprazole; Male; Middle Aged; Polymorphism, Genetic; Proton Pump Inhibitors; Rabeprazole; Retrospective Studies; Tacrolimus

2014
Influence of Proton Pump Inhibitors on Mycophenolic Acid Pharmacokinetics in Patients With Renal Transplantation and the Relationship With Cytochrome 2C19 Gene Polymorphism.
    Transplantation proceedings, 2017, Volume: 49, Issue:3

    Topics: Adult; Cytochrome P-450 CYP2C19; Drug Interactions; Drug Therapy, Combination; Female; Genotype; Humans; Immunosuppressive Agents; Kidney Transplantation; Lansoprazole; Male; Middle Aged; Mycophenolic Acid; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Proton Pump Inhibitors; Rabeprazole; Retrospective Studies; Tacrolimus

2017