lamotrigine has been researched along with riluzole in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (23.33) | 18.2507 |
| 2000's | 14 (46.67) | 29.6817 |
| 2010's | 8 (26.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Boireau, A; Bordier, F; Doble, A; Dubédat, P | 1 |
| Mary, V; Stutzmann, JM; Wahl, F | 1 |
| Obrenovitch, TP | 1 |
| Klivényi, P; Vécsei, L | 1 |
| Gernert, M; Löscher, W; Richter, A | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
| Hölter, SM; Hundt, W; Spanagel, R | 1 |
| Cahill, CM; Coderre, TJ; Fisher, K; Lefebvre, C | 1 |
| Bernardi, G; Caputi, L; Hainsworth, AH; Lavaroni, F; Martella, G; Mercuri, NB; Spadoni, F; Stefani, A | 1 |
| Krystal, AD; Singh, J; Zarate, CA | 1 |
| Kugaya, A; Sanacora, G | 1 |
| Bezprozvanny, I; Tang, T; Wu, J | 1 |
| Coderre, TJ; Kumar, N; Lefebvre, CD; Yu, JS | 1 |
| Howland, RH | 1 |
| aan het Rot, M; Charney, DS; Collins, KA; Mathew, SJ; Murrough, JW; Reich, DL | 1 |
| Drevets, WC; Henter, ID; Manji, HK; Salvadore, G; Zarate, CA | 1 |
| Alexopoulos, GS; Asemota, B; Mahgoub, N | 1 |
| Chen, W; Huang, P; Sun, M; Wang, Y | 1 |
| Deng, Y; Li, RW; Smith, PN; Weiss, S; Yang, YL | 1 |
7 review(s) available for lamotrigine and riluzole
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Sodium and potassium channel modulators: their role in neuroprotection.
Topics: Animals; Benzeneacetamides; Cell Survival; Disease Models, Animal; Lamotrigine; Neurons; Neuroprotective Agents; Piperazines; Piperidines; Potassium Channels; Pyrimidines; Riluzole; Sodium Channels; Thiazoles; Triazines | 1997 |
[Neurodegeneration: aging and dementia. Etiopathogenic role of electron transport disorders. Therapeutic possibilities].
Topics: Aged; Aging; Alzheimer Disease; Calcium Channel Blockers; Cerebellar Diseases; Dementia; Electron Transport; Female; Humans; Huntington Disease; Lamotrigine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Parkinson Disease; Riluzole; Thiazoles; Triazines | 1997 |
Beyond monoamines: glutamatergic function in mood disorders.
Topics: Bipolar Disorder; Brain; Clinical Trials as Topic; Depressive Disorder, Major; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Neuroglia; Receptors, Glutamate; Riluzole; Treatment Outcome; Triazines | 2005 |
Glutamate-modulating drugs & the treatment of mental disorders.
Topics: Acamprosate; Amantadine; Cycloserine; Glutamic Acid; Humans; Ketamine; Lamotrigine; Memantine; Mental Disorders; Psychotropic Drugs; Riluzole; Taurine; Triazines | 2007 |
Early intervention in bipolar disorder, part II: therapeutics.
Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Brain; Early Diagnosis; Humans; Lamotrigine; Lithium Compounds; Riluzole; Triazines; Valproic Acid | 2008 |
1 trial(s) available for lamotrigine and riluzole
| Article | Year |
|---|---|
Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial.
Topics: Adult; Aged; Depression; Drug Interactions; Drug Resistance; Excitatory Amino Acid Antagonists; Female; Hallucinogens; Humans; Injections, Intravenous; Ketamine; Lamotrigine; Male; Middle Aged; Pilot Projects; Placebos; Riluzole; Secondary Prevention; Time Factors; Treatment Outcome; Triazines | 2010 |
22 other study(ies) available for lamotrigine and riluzole
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Methamphetamine and dopamine neurotoxicity: differential effects of agents interfering with glutamatergic transmission.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dizocilpine Maleate; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Lamotrigine; Male; Methamphetamine; Mice; Mice, Inbred Strains; Neostriatum; Neurons; Riluzole; Sodium Channels; Synaptic Transmission; Thiazoles; Triazines | 1995 |
Effect of riluzole on quinolinate-induced neuronal damage in rats: comparison with blockers of glutamatergic neurotransmission.
Topics: Animals; Anticonvulsants; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Lamotrigine; Male; Neurons; Quinolinic Acid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Riluzole; Synaptic Transmission; Thiazoles; Triazines | 1995 |
Prodystonic effects of riluzole in an animal model of idiopathic dystonia related to decreased total power in the red nucleus?
Topics: Animals; Antiparkinson Agents; Calcium Channel Blockers; Cricetinae; Disease Models, Animal; Dystonia; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; Lamotrigine; Neuroprotective Agents; Riluzole; Triazines | 1997 |
Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Antagonists; Lamotrigine; Male; Neurons; Neuroprotective Agents; Phenytoin; Rats; Rats, Wistar; Riluzole; Sodium; Thiazoles; Triazines | 1997 |
Discriminative stimulus effects of glutamate release inhibitors in rats trained to discriminate ethanol.
Topics: Animals; Calcium Channel Blockers; Central Nervous System Depressants; Conditioning, Operant; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Lamotrigine; Male; Rats; Rats, Wistar; Riluzole; Triazines | 1998 |
Evidence that DHPG-induced nociception depends on glutamate release from primary afferent C-fibres.
Topics: 4-Aminopyridine; Animals; Behavior, Animal; Capsaicin; Excitatory Amino Acid Agonists; Glutamic Acid; Injections, Spinal; Lamotrigine; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Neurons, Afferent; Nociceptors; Proline; Propionates; Rats; Rats, Long-Evans; Riluzole; Triazines | 2000 |
Lamotrigine derivatives and riluzole inhibit INa,P in cortical neurons.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsy; Lamotrigine; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Piperazines; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Riluzole; Sodium; Sodium Channel Blockers; Sodium Channels; Triazines | 2002 |
Case report: Successful riluzole augmentation therapy in treatment-resistant bipolar depression following the development of rash with lamotrigine.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Drug Synergism; Exanthema; Excitatory Amino Acid Antagonists; Humans; Lamotrigine; Male; Riluzole; Treatment Outcome; Triazines | 2004 |
Evaluation of clinically relevant glutamate pathway inhibitors in in vitro model of Huntington's disease.
Topics: Amines; Animals; Apoptosis; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Folic Acid; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Lamotrigine; Male; Memantine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Riluzole; Triazines | 2006 |
A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain.
Topics: Amines; Analgesics; Animals; Anticonvulsants; Cold Temperature; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Lamotrigine; Male; Microdialysis; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Long-Evans; Riluzole; Spinal Cord; Touch; Triazines | 2007 |
The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Topics: Adult; Clonazepam; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Fructose; GABA Modulators; Humans; Lamotrigine; Male; Monoamine Oxidase Inhibitors; Obsessive-Compulsive Disorder; Phenelzine; Riluzole; Topiramate; Treatment Outcome; Triazines | 2011 |
Anticonvulsants lamotrigine and riluzole disrupt maternal behavior in postpartum female rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Dose-Response Relationship, Drug; Female; Glutamic Acid; Lamotrigine; Maternal Behavior; Postpartum Period; Rats, Sprague-Dawley; Riluzole | 2018 |
Pharmacological prevention of renal ischemia-reperfusion injury in a rat model.
Topics: Animals; Glutathione; Humans; Ischemia; Kidney; Lamotrigine; Lidocaine; Rats; Reperfusion Injury; Riluzole | 2022 |