lamotrigine has been researched along with morphine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bowery, NG; Fowler, LJ; Teoh, H | 1 |
| Cuéllar, B; Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| De Laat, M; Devulder, J | 1 |
| Argüelles, CF; Granados-Soto, V; Torres-López, JE | 1 |
| Bakhtiarian, A; Daryaafzoon, M; Ejtemaeemehr, S; Sahraei, H; Tehrani, SP | 1 |
| Chavooshi, B; Saberi, M | 1 |
| Habibi-Asl, B; Hassanzadeh, K; Mohammadi, S; Vafai, H | 1 |
| Jun, IG; Kim, SH; Park, JY; Yoon, YI | 1 |
2 review(s) available for lamotrigine and morphine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
15 other study(ies) available for lamotrigine and morphine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Effect of lamotrigine on the electrically-evoked release of endogenous amino acids from slices of dorsal horn of the rat spinal cord.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Evoked Potentials; Glutamic Acid; Lamotrigine; Male; Morphine; Rats; Rats, Wistar; Spinal Cord; Triazines | 1995 |
Inhibition of morphine withdrawal by lamotrigine: involvement of nitric oxide.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Lamotrigine; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Substance Withdrawal Syndrome; Triazines | 1996 |
Lamotrigine in the treatment of chronic refractory neuropathic pain.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Chronic Disease; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Morphine; Nervous System Diseases; Pain; Palliative Care; Prospective Studies; Triazines | 2000 |
Peripheral antinociceptive action of morphine and the synergistic interaction with lamotrigine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Female; Lamotrigine; Male; Morphine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Triazines | 2002 |
The effects of lamotrigine on the acquisition and expression of morphine-induced place preference in mice.
Topics: Animals; Anticonvulsants; Behavior, Animal; Conditioning, Psychological; Humans; Lamotrigine; Male; Mice; Morphine; Narcotics; Triazines | 2009 |
Suppressive effects of lamotrigine on the development and expression of tolerance to morphine-induced antinociception in the male mouse.
Topics: Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Tolerance; Lamotrigine; Male; Mice; Morphine; Pain Measurement; Pain Threshold; Tachyphylaxis; Triazines | 2009 |
Development of morphine induced tolerance and withdrawal symptoms is attenuated by lamotrigine and magnesium sulfate in mice.
Topics: Analgesics; Animals; Calcium Channels; Dose-Response Relationship, Drug; Drug Tolerance; Lamotrigine; Magnesium Sulfate; Male; Mice; Morphine; Morphine Dependence; Naloxone; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Temperature; Triazines | 2009 |
Intrathecal lamotrigine attenuates antinociceptive morphine tolerance and suppresses spinal glial cell activation in morphine-tolerant rats.
Topics: Analgesics; Animals; Astrocytes; CD11b Antigen; Drug Tolerance; Immunohistochemistry; Lamotrigine; Male; Microglia; Morphine; Nerve Tissue Proteins; Neuroglia; Rats; Rats, Sprague-Dawley; Spinal Cord; Triazines | 2013 |