lamotrigine and lidocaine

lamotrigine has been researched along with lidocaine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's14 (56.00)29.6817
2010's9 (36.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Anger, T; Madge, DJ; Mulla, M; Riddall, D1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Barthelemy, MA; Bigg, D; Chabrier, PE; Huchet, M; Liberatore, AM; Pommier, J; Schulz, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bernardi, G; Guatteo, E; Mercuri, NB; Siniscalchi, A; Zona, C1
Blackburn-Munro, G; Erichsen, HK; Hao, JX; Xu, XJ1
Ghetti, A; Guia, A; Manalo, G; Santaana, D; Tao, H; Xie, B; Xu, J1
Martin, WJ; Ritchie, C; Ritter, AM1
Cohen, AS1
Cohen, AS; Goadsby, PJ1
Broadley, SA; Williams, MH1
Lambru, G; Matharu, MS1
Tikhonov, DB; Zhorov, BS1
Baraldi, C; Cainazzo, MM; Guerzoni, S; Pellesi, L; Pini, LA1
Fedorova, IM; Tikhonov, DB1
Deng, Y; Li, RW; Smith, PN; Weiss, S; Yang, YL1

Reviews

5 review(s) available for lamotrigine and lidocaine

ArticleYear
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke

2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pathophysiology and treatment of trigeminal autonomic cephalalgias].
    Schmerz (Berlin, Germany), 2008, Volume: 22 Suppl 1

    Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Methysergide; Nociceptors; Oxygen Inhalation Therapy; Paroxysmal Hemicrania; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias; Trigeminal Nerve; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

2008
SUNCT and SUNA: medical and surgical treatments.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2013, Volume: 34 Suppl 1

    Topics: Analgesics; Headache; Humans; Lamotrigine; Lidocaine; SUNCT Syndrome; Triazines; Trigeminal Autonomic Cephalalgias

2013
Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Neuralgia; Paroxysmal Hemicrania; Reproducibility of Results; SUNCT Syndrome; Surveys and Questionnaires; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias

2017

Trials

1 trial(s) available for lamotrigine and lidocaine

ArticleYear
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:7

    Topics: Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Autonomic Nervous System Diseases; Cohort Studies; Conjunctiva; Cyclohexanecarboxylic Acids; Fructose; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothalamus, Posterior; Indomethacin; Lamotrigine; Lidocaine; Magnetic Resonance Imaging; Oxygen; Pain Measurement; Phenotype; Prospective Studies; SUNCT Syndrome; Tears; Topiramate; Triazines

2007

Other Studies

19 other study(ies) available for lamotrigine and lidocaine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
2-Alkyl-4-arylimidazoles: structurally novel sodium channel modulators.
    Bioorganic & medicinal chemistry letters, 2004, Jul-05, Volume: 14, Issue:13

    Topics: Animals; Benzimidazoles; Binding Sites; Brain; Carbolines; Cells, Cultured; Electrophysiology; Inhibitory Concentration 50; Rats; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Veratridine

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
An electrophysiological analysis of the protective effects of felbamate, lamotrigine, and lidocaine on the functional recovery from in vitro ischemia in rat neocortical slices.
    Synapse (New York, N.Y.), 1998, Volume: 30, Issue:4

    Topics: Action Potentials; Animals; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Felbamate; In Vitro Techniques; Ischemia; Lamotrigine; Lidocaine; Male; Neuroprotective Agents; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar; Triazines

1998
A comparison of the antinociceptive effects of voltage-activated Na+ channel blockers in two rat models of neuropathic pain.
    European journal of pharmacology, 2003, Jan-05, Volume: 458, Issue:3

    Topics: Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hindlimb; Lamotrigine; Lidocaine; Male; Mexiletine; Neuralgia; Pain Measurement; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Time Factors; Tocainide; Triazines

2003
Efficient characterization of use-dependent ion channel blockers by real-time monitoring of channel state.
    Assay and drug development technologies, 2006, Volume: 4, Issue:1

    Topics: Carbamazepine; Cell Line; Electrophysiology; Humans; Kinetics; Lamotrigine; Lidocaine; Membrane Potentials; Membrane Transport Modulators; Monitoring, Physiologic; Muscle Proteins; NAV1.4 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Reproducibility of Results; Sodium Channels; Tetracaine; Transfection; Triazines

2006
Relationship between the firing frequency of injured peripheral neurons and inhibition of firing by sodium channel blockers.
    The journal of pain, 2007, Volume: 8, Issue:4

    Topics: Anesthetics, Local; Animals; Denervation; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Lamotrigine; Lidocaine; Male; Neurons; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sodium Channel Blockers; Spinal Nerves; Triazines

2007
SUNCT and SUNA: clinical features and medical treatment.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2008, Volume: 15, Issue:5

    Topics: Adult; Aged; Anesthetics; Female; Humans; Incidence; Lamotrigine; Lidocaine; Male; Middle Aged; Prevalence; Retrospective Studies; Statistics, Nonparametric; SUNCT Syndrome; Triazines; Trigeminal Autonomic Cephalalgias

2008
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
    The Journal of general physiology, 2017, Apr-03, Volume: 149, Issue:4

    Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines

2017
Lidocaine and carbamazepine inhibit while phenytoin and lamotrigine paradoxically enhance the insect neuromuscular transmission.
    Invertebrate neuroscience : IN, 2019, 02-08, Volume: 19, Issue:1

    Topics: Anesthetics, Local; Animals; Anticonvulsants; Carbamazepine; Diptera; Lamotrigine; Lidocaine; Phenytoin; Synaptic Transmission; Voltage-Gated Sodium Channel Blockers

2019
Pharmacological prevention of renal ischemia-reperfusion injury in a rat model.
    ANZ journal of surgery, 2022, Volume: 92, Issue:3

    Topics: Animals; Glutathione; Humans; Ischemia; Kidney; Lamotrigine; Lidocaine; Rats; Reperfusion Injury; Riluzole

2022