lamotrigine has been researched along with diazepam in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.67) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 10 (33.33) | 24.3611 |
| 2020's | 3 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, MS; Edafiogho, IO; Farrar, VA; Kolen, KR; Moore, JA; Rankin, GO; Scott, KR; Sims, LD; Stables, JP; Tonnu, AD | 1 |
| Bonsignori, A; Colombo, M; Dostert, P; Fariello, RG; Heidempergher, F; McArthur, RA; Pevarello, P; Pinciroli, V; Post, C; Salvati, P; Varasi, M | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jawad, S; Oxley, J; Richens, A; Yuen, WC | 1 |
| Ashby, L; Cohen, AF; Crowley, D; Land, G; Miller, AA; Peck, AW | 1 |
| al-Zubaidy, ZA; Chapman, AG; Meldrum, BS; Smith, SE | 1 |
| Aguglia, U; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Fariello, RG; Maj, R; McArthur, RA; Pevarello, P; Salvati, P; Ukmar, G; Varasi, M | 1 |
| Heynen, T; Krupp, E; Li, XL; Post, RM; Weiss, SR | 1 |
| Jagoda, A; Yoon, Y | 1 |
| Bloem, BR; Renier, WO; Voermans, NC; Zwarts, MJ | 1 |
| Burakov, AM; Grinenko, AA; Gueorguieva, R; Krupitsky, EM; Krystal, JH; Petrakis, IL; Pittman, B; Rudenko, AA; Slavina, TY; Zvartau, EE | 1 |
| Böttiger, BW; Dagtekin, O; Marcus, H; Müller, C; Spöhr, F | 1 |
| Acree, WE; Jouyban, A; Panahi-Azar, V; Shayanfar, A; Soleymani, J; York, P; Yousefi, BH | 1 |
| Barker-Haliski, M; Knox, KM; Koneval, Z; Memon, A; White, HS; Zierath, DK | 1 |
| Amagai, M; Fukasawa, T; Takahashi, H; Takahashi, K; Tanemura, N; Urushihara, H | 1 |
| Hume, AL; Lawal, OD; Meador, KJ; Wen, X | 1 |
3 review(s) available for lamotrigine and diazepam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
3 trial(s) available for lamotrigine and diazepam
| Article | Year |
|---|---|
The effect of lamotrigine, a novel anticonvulsant, on interictal spikes in patients with epilepsy.
Topics: Adult; Anticonvulsants; Clinical Trials as Topic; Diazepam; Double-Blind Method; Electroencephalography; Epilepsy; Humans; Lamotrigine; Random Allocation; Triazines | 1986 |
Lamotrigine (BW430C), a potential anticonvulsant. Effects on the central nervous system in comparison with phenytoin and diazepam.
Topics: Adult; Anticonvulsants; Brain; Diazepam; Eye Movements; Humans; Hypnotics and Sedatives; Lamotrigine; Male; Movement; Phenytoin; Psychomotor Performance; Saliva; Triazines | 1985 |
Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam.
Topics: Adult; Alcoholism; Arousal; Autonomic Nervous System; Depression; Diazepam; Excitatory Amino Acid Antagonists; Fructose; GABA Modulators; Humans; Inpatients; Lamotrigine; Male; Memantine; Middle Aged; Mood Disorders; Substance Withdrawal Syndrome; Topiramate; Triazines | 2007 |
24 other study(ies) available for lamotrigine and diazepam
| Article | Year |
|---|---|
Synthesis and anticonvulsant activity of enaminones. 3. Investigations on 4'-, 3'-, and 2'-substituted and polysubstituted anilino compounds, sodium channel binding studies, and toxicity evaluations.
Topics: Animals; Anticonvulsants; Batrachotoxins; Kidney; Liver; Male; Mice; Rats; Rats, Inbred F344; Sodium Channels; Structure-Activity Relationship | 1995 |
Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats | 2007 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Epilepsy; Female; Lamotrigine; Male; Motor Activity; Phenytoin; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Triazines | 1993 |
Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Diazepam; Drug Synergism; Female; Lamotrigine; Male; Mice; Mice, Inbred DBA; Phenytoin; Seizures; Triazines; Valproic Acid | 1996 |
PNU-151774E protects against kainate-induced status epilepticus and hippocampal lesions in the rat.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Diazepam; Epilepsy; Hippocampus; Kainic Acid; Lamotrigine; Male; Neuroprotective Agents; Rats; Rats, Wistar; Triazines | 1998 |
Tolerance to the anticonvulsant effects of lamotrigine on amygdala kindled seizures: cross-tolerance to carbamazepine but not valproate or diazepam.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Electric Stimulation; Electrodes, Implanted; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Seizures; Triazines; Valproic Acid | 2000 |
[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy].
Topics: Adult; Anticonvulsants; Cesarean Section; Clonazepam; Diazepam; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Lamotrigine; Midazolam; Obstetric Labor Complications; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Triazines | 2005 |
Lipid therapy for serotonin syndrome after intoxication with venlafaxine, lamotrigine and diazepam.
Topics: Adult; Combined Modality Therapy; Cyclohexanols; Diazepam; Emulsions; Fat Emulsions, Intravenous; Female; Humans; Lamotrigine; Lipids; Muscle Rigidity; Reflex, Abnormal; Renal Dialysis; Serotonin Syndrome; Suicide, Attempted; Triazines; Venlafaxine Hydrochloride | 2011 |
Solubility prediction of drugs in mixed solvents using partial solubility parameters.
Topics: Clonazepam; Computer Simulation; Diazepam; Ethanol; Ibuprofen; Kinetics; Lamotrigine; Models, Molecular; Numerical Analysis, Computer-Assisted; Pharmaceutical Preparations; Phenobarbital; Propylene Glycol; Solubility; Solvents; Technology, Pharmaceutical; Temperature; Triazines; Water | 2011 |
Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.
Topics: Animals; Animals, Outbred Strains; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Cornea; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistant Epilepsy; Electroshock; Kindling, Neurologic; Lamotrigine; Levetiracetam; Locomotion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Open Field Test; Phenobarbital; Seizures; Treatment Outcome; Valproic Acid | 2020 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with anticonvulsants in a Japanese population: Matched case-control and cohort studies.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Clonazepam; Cohort Studies; Diazepam; Female; Humans; Incidence; Japan; Lamotrigine; Levetiracetam; Logistic Models; Male; Middle Aged; Odds Ratio; Phenytoin; Risk Factors; Stevens-Johnson Syndrome | 2021 |
Utilization of Antiseizure Medications in Women of Childbearing Age With Epilepsy and Nonepilepsy Indications: A Retrospective Cohort Study.
Topics: Anticonvulsants; Clonazepam; Diazepam; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Lorazepam; Retrospective Studies; Topiramate; Valproic Acid | 2023 |