lamotrigine and aspartic acid

lamotrigine has been researched along with aspartic acid in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's6 (37.50)18.2507
2000's4 (25.00)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Meldrum, BS1
Porter, RJ1
Bowery, NG; Fowler, LJ; Teoh, H1
Martin, P; Portet, C; Schmutz, M; Stöcklin, K; Waldmeier, PC1
Attwell, PJ; Bradford, HF; Croucher, MJ; Jane, DE; Singh Kent, N1
Eriksson, AS; O'Connor, WT1
Afanas'ev, I; Kudrin, V; Oja, SS; Rayevsky, KS; Saransaari, P; Varga, V1
Chang, C; Lee, WT; Shen, YZ1
Askmark, H; Persson, LI; Ryberg, H1
Ahmad, S; Fowler, LJ; Whitton, PS1
Halasz, S; Kliment, E; Sumegi, A1
Dalley, JW; Fernando, AB; Mar, AC; Murphy, ER; Robbins, TW; Robinson, ES; Theobald, DE; Urcelay, GP1
Deng, Y; He, N; Ma, C; Wang, M; Wang, W1
Abulseoud, OA; Baruth, JM; Choi, DS; Croarkin, PE; Frye, MA; Port, JD; Thomas, MA1
Forester, BP; Harper, DG; Jensen, E; Mellen, EJ; Ravichandran, C; Silveri, M1

Reviews

1 review(s) available for lamotrigine and aspartic acid

ArticleYear
Excitatory amino acid transmitters in epilepsy.
    Epilepsia, 1991, Volume: 32 Suppl 2

    Topics: Anticonvulsants; Aspartic Acid; Epilepsy; Epilepsy, Temporal Lobe; Glutamates; Glutamic Acid; Humans; Ion Channels; Lamotrigine; Neurotransmitter Agents; Triazines

1991

Trials

1 trial(s) available for lamotrigine and aspartic acid

ArticleYear
A double-blind randomized clinical trial in amyotrophic lateral sclerosis using lamotrigine: effects on CSF glutamate, aspartate, branched-chain amino acid levels and clinical parameters.
    Acta neurologica Scandinavica, 2003, Volume: 108, Issue:1

    Topics: Adult; Aged; Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Aspartic Acid; Cross-Over Studies; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Lamotrigine; Male; Middle Aged; Outcome Assessment, Health Care; Triazines

2003

Other Studies

14 other study(ies) available for lamotrigine and aspartic acid

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Mechanisms of action of new antiepileptic drugs.
    Epilepsia, 1989, Volume: 30 Suppl 1

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin

1989
Effect of lamotrigine on the electrically-evoked release of endogenous amino acids from slices of dorsal horn of the rat spinal cord.
    Neuropharmacology, 1995, Volume: 34, Issue:10

    Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Dose-Response Relationship, Drug; Evoked Potentials; Glutamic Acid; Lamotrigine; Male; Morphine; Rats; Rats, Wistar; Spinal Cord; Triazines

1995
Effect of carbamazepine, oxcarbazepine and lamotrigine on the increase in extracellular glutamate elicited by veratridine in rat cortex and striatum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:2

    Topics: Animals; Anticonvulsants; Aspartic Acid; Carbamazepine; Cerebral Cortex; Corpus Striatum; Glutamic Acid; Lamotrigine; Male; Microdialysis; Oxcarbazepine; Rats; Triazines; Veratridine

1996
Anticonvulsant and glutamate release-inhibiting properties of the highly potent metabotropic glutamate receptor agonist (2S,2'R, 3'R)-2-(2',3'-dicarboxycyclopropyl)glycine (DCG-IV).
    Brain research, 1998, Sep-14, Volume: 805, Issue:1-2

    Topics: Amygdala; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Cyclopropanes; Glutamic Acid; Glycine; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Synaptosomes; Triazines

1998
Analysis of CSF amino acids in young patients with generalised refractory epilepsy during an add-on study with lamotrigine.
    Epilepsy research, 1999, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Amino Acids; Anticonvulsants; Aspartic Acid; Child; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Epilepsy, Generalized; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Lamotrigine; Male; Treatment Outcome; Triazines

1999
Lamotrigine and carbamazepine affect differently the release of D-[3H]aspartate from mouse cerebral cortex slices: involvement of NO.
    Neurochemical research, 1999, Volume: 24, Issue:9

    Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Carbamazepine; Cerebral Cortex; Enzyme Inhibitors; In Vitro Techniques; Lamotrigine; Male; Mice; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Triazines; Tritium

1999
Neuroprotective effect of lamotrigine and MK-801 on rat brain lesions induced by 3-nitropropionic acid: evaluation by magnetic resonance imaging and in vivo proton magnetic resonance spectroscopy.
    Neuroscience, 2000, Volume: 95, Issue:1

    Topics: Animals; Aspartic Acid; Behavior, Animal; Brain; Choline; Corpus Striatum; Creatine; Dizocilpine Maleate; Hippocampus; In Vitro Techniques; Lamotrigine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neuroprotective Agents; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Triazines

2000
Effects of acute and chronic lamotrigine treatment on basal and stimulated extracellular amino acids in the hippocampus of freely moving rats.
    Brain research, 2004, Dec-10, Volume: 1029, Issue:1

    Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain Chemistry; Dose-Response Relationship, Drug; Drug Administration Schedule; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Lamotrigine; Male; Microdialysis; Potassium Chloride; Rats; Rats, Wistar; Taurine; Triazines; Veratridine

2004
[Application of lamotrigine in bipolar disorder--3T MR spectroscopy follow up (part 1)].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2010, Volume: 12, Issue:3

    Topics: Antimanic Agents; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Excitatory Amino Acid Antagonists; Female; Hippocampus; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Treatment Outcome; Triazines; Young Adult

2010
Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex.
    Psychopharmacology, 2012, Volume: 219, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Outbred Strains; Aspartic Acid; Bicuculline; Choice Behavior; GABA-A Receptor Agonists; Impulsive Behavior; Lamotrigine; Male; Microinjections; Muscimol; Piperazines; Prefrontal Cortex; Rats; Receptors, N-Methyl-D-Aspartate; Serial Learning; Triazines

2012
Comparison and effects of acute lamotrigine treatment on extracellular excitatory amino acids in the hippocampus of PTZ-kindled epileptic and PTZ-induced status epilepticus rats.
    Neurochemical research, 2013, Volume: 38, Issue:3

    Topics: Animals; Aspartic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kindling, Neurologic; Lamotrigine; Male; Neurotransmitter Agents; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Status Epilepticus; Triazines

2013
N-acetylaspartate normalization in bipolar depression after lamotrigine treatment.
    Bipolar disorders, 2015, Volume: 17, Issue:4

    Topics: Adult; Aged; Aspartic Acid; Biomarkers; Bipolar Disorder; Brain; Dipeptides; Female; Gyrus Cinguli; Humans; Lamotrigine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values; Triazines

2015
Lamotrigine Therapy and Biomarkers of Cerebral Energy Metabolism in Older Age Bipolar Depression.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019, Volume: 27, Issue:8

    Topics: Aged; Aging; Antipsychotic Agents; Aspartic Acid; Biomarkers; Bipolar Disorder; Cerebral Cortex; Creatine; Depression; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Humans; Lamotrigine; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Severity of Illness Index; Treatment Outcome

2019