lamotrigine has been researched along with acetaminophen in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 16 (72.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cloutier, G; Dalton, MJ; Depot, M; Messenheimer, JA; Powell, JR | 1 |
| Baricault, S; Bravard, P; Carré-Gislard, D; Le Loarer, F | 1 |
| Cuadrado, ML; Fernández, R; García-Ramos, R; Gómez-Vicente, L; Guerrero, AL; Herrero, S; Peñas, ML; Porta-Etessam, J | 1 |
| Gilson, R; Henning, JS; Ladd, D; Reese, D; Rockers, K | 1 |
| Hantson, P; Wittebole, X | 1 |
| Benoliel, R; Eliav, E | 1 |
| Arakawa, H; Ikeya, T; Inoue, Y; Iwai, H; Jomura, T; Koeda, A; Kusumoto, K; Nagao, T; Naitoh, K; Ogihara, T; Ohkura, T; Ohta, K; Ozeki, E; Takahashi, N; Ueda, T; Wada, K | 1 |
| Kim, SR; Koh, BS; Lee, JH; Leem, DW; Moon, IJ; Park, HJ; Park, JW; Park, KH | 1 |
| Damkier, P; Fruekilde, PB; Gastrup, S; Stage, TB | 1 |
| Arakawa, H; Itoh, M; Kojima, H; Koyama, S; Masuda, N; Ogihara, T; Yano, K | 1 |
| Battini, V; Carnovale, C; Clementi, E; Gringeri, M; Mazhar, F; Mosini, G; Pozzi, M; Radice, S | 1 |
| Nakamura, R; Saito, Y | 1 |
6 review(s) available for lamotrigine and acetaminophen
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Cyclosporine for SJS/TEN: a case series and review of the literature.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Infective Agents; Anticonvulsants; Cyclosporine; Dermatologic Agents; Drug Combinations; Female; Humans; Lamotrigine; Male; Stevens-Johnson Syndrome; Sulfamethizole; Triazines; Trimethoprim | 2011 |
Use of the molecular adsorbent recirculating system (MARS™) for the management of acute poisoning with or without liver failure.
Topics: Acetaminophen; Acute Disease; Albumins; Amanita; Amphetamine; Calcium Channel Blockers; Cocaine; Heavy Metal Poisoning; Humans; Lamotrigine; Liver Failure; Liver, Artificial; Metals, Heavy; Mushroom Poisoning; Phenytoin; Poisoning; Sorption Detoxification; Triazines | 2011 |
Primary headache disorders.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Chronic Disease; Cluster Headache; Cyclooxygenase Inhibitors; Diagnosis, Differential; Headache Disorders, Primary; Humans; Indomethacin; Lamotrigine; Migraine Disorders; Paroxysmal Hemicrania; Sumatriptan; SUNCT Syndrome; Tension-Type Headache; Triazines; Trigeminal Autonomic Cephalalgias; Vasoconstrictor Agents | 2013 |
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy].
Topics: Acetaminophen; Adrenal Cortex Hormones; Allopurinol; Antigens, Differentiation, T-Lymphocyte; Carbamazepine; CD8-Positive T-Lymphocytes; Cyclosporine; Epidermis; Etanercept; Fas Ligand Protein; HLA Antigens; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Japan; Lamotrigine; Plasma Exchange; Stevens-Johnson Syndrome; Tumor Necrosis Factor-alpha | 2019 |
2 trial(s) available for lamotrigine and acetaminophen
| Article | Year |
|---|---|
Kinetic effects of multiple oral doses of acetaminophen on a single oral dose of lamotrigine.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Double-Blind Method; Humans; Lamotrigine; Least-Squares Analysis; Male; Middle Aged; Triazines | 1990 |
Paracetamol decreases steady-state exposure to lamotrigine by induction of glucuronidation in healthy subjects.
Topics: Acetaminophen; Anticonvulsants; Area Under Curve; Dose-Response Relationship, Drug; Drug Interactions; Glucuronides; Healthy Volunteers; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Tissue Distribution; Triazines | 2016 |
14 other study(ies) available for lamotrigine and acetaminophen
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Severe drug eruption caused by a medication error].
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Anticonvulsants; Female; Hospitalization; Humans; Lamotrigine; Medical Errors; Methylprednisolone; Middle Aged; Treatment Outcome; Triazines | 2009 |
Epicrania fugax: ten new cases and therapeutic results.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Lamotrigine; Male; Middle Aged; Nerve Block; Pain Measurement; Treatment Outcome; Triazines; Young Adult | 2010 |
Evaluation of human hepatocytes cultured by three-dimensional spheroid systems for drug metabolism.
Topics: Acetaminophen; Albuterol; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Diclofenac; Glucuronosyltransferase; Hepatocytes; Humans; Lamotrigine; Midazolam; Pharmaceutical Preparations; Propranolol; Spheroids, Cellular; Tandem Mass Spectrometry; Triazines | 2014 |
Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine.
Topics: Acetaminophen; Acetazolamide; Adult; Aged; Aged, 80 and over; Alleles; Allopurinol; Anti-Bacterial Agents; Anticonvulsants; Asian People; Female; Genetic Predisposition to Disease; HLA-B Antigens; Humans; Lamotrigine; Male; Middle Aged; Plants, Medicinal; Republic of Korea; Stevens-Johnson Syndrome; Tertiary Care Centers; Triazines; Young Adult | 2015 |
Evaluation of the metabolic capability of primary human hepatocytes in three-dimensional cultures on microstructural plates.
Topics: Acetaminophen; Adenosine Triphosphate; Arylsulfotransferase; Cell Culture Techniques; Cells, Cultured; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme System; Diclofenac; Glucuronosyltransferase; Hepatocytes; Humans; Lamotrigine; Midazolam; Omeprazole; Rifampin; RNA, Messenger; Triazines | 2018 |
Interaction between paracetamol and lamotrigine: new insights from the FDA Adverse Event Reporting System (FAERS) database.
Topics: Acetaminophen; Adverse Drug Reaction Reporting Systems; Databases, Factual; Drug Interactions; Humans; Lamotrigine; United States; United States Food and Drug Administration | 2019 |