lamivudine has been researched along with zidovudine in 1507 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 429 (28.47) | 18.2507 |
2000's | 715 (47.45) | 29.6817 |
2010's | 316 (20.97) | 24.3611 |
2020's | 47 (3.12) | 2.80 |
Authors | Studies |
---|---|
Beach, JW; Choi, BG; Chu, CK; Chun, MW; Chung, WK; Jeong, LS; Kim, HO; Nampalli, S; Schinazi, RF; Shanmuganathan, K | 1 |
Alves, AJ; Beach, JW; Chu, CK; Jeong, LS; Kim, HO; Mathis, R; McMillan, A; Nampalli, S; Schinazi, RF; Shanmuganathan, K | 1 |
Cha, SH; Endou, H; Kanai, Y; Kimura, M; Sekine, T; Tsuda, M; Wada, S | 1 |
Bader, JP; Cragg, GM; Newman, DJ; Yang, SS | 1 |
Gochfeld, DJ; Hamann, MT | 1 |
D'Aquila, RT; De Pasquale, MP; Olson, DP; Scadden, DT | 1 |
Choi, Y; Chong, Y; Choo, H; Chu, CK; Mathew, J; Schinazi, RF | 1 |
Akiyama, S; Baba, M; Furukawa, T; Nitanda, T; Okamoto, M; Sugimoto, Y; Wang, X | 1 |
Chong, Y; Chu, CK; Gumina, G; Mathew, JS; Schinazi, RF | 1 |
Chong, Y; Choo, H; Chu, CK; Mathews, J; Schinazi, RF; Zhu, W | 1 |
Chong, Y; Chu, CK; Gumina, G; Schinazi, RF; Wang, J; Zhou, W | 1 |
Cheng, YC; Drach, JC; Gullen, E; Kern, ER; Matsumi, S; Mitsuya, H; Zemlicka, J; Zhou, S | 1 |
Bennett, M; Chu, CK; Jin, Y; Rapp, KL; Schinazi, RF; Wang, J | 1 |
Jolivette, LJ; Ward, KW | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Cheng, YC; Drach, JC; Gullen, E; Kern, ER; Mitsuya, H; Tamiya, S; Zemlicka, J; Zhou, S | 1 |
Baba, M; De Clercq, E; Shi, M; Takao, S; Wang, X | 1 |
Capparelli, E; Flynn, PM; Heckman, B; Knapp, KM; Lindsey, JC; Martinez, J; McNamara, J; Robbins, B; Rodman, J; Rodriguez, JF; Serchuck, L | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A | 1 |
Anderson, DJ; Gottlieb, GS; Preston, BD; Pyrak, CL; Smith, RA | 1 |
Beadle, JR; Bradley, M; Farasati, NA; Hostetler, KY; Huang, Y; Meier, C; Randhawa, P; Sauerbrei, A; Zemlicka, J | 1 |
Colonno, R; Dicker, I; Fan, L; Gali, V; Higley, H; Krystal, M; Lin, PF; Nowicka-Sans, B; Parkin, N; Tenney, D; Terry, B; Wang, C; Zhang, S | 1 |
Chen, JJ; Cheng, P; Jiang, ZY; Ma, YB; Yan, MH; Yang, LM; Zhang, FX; Zhang, XM; Zheng, YT | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Haas, RH; Naviaux, RK; Saitoh, A; Salva, NG; Spector, SA; Wong, JK | 1 |
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E | 1 |
Bachmann, MH; Fessel, WJ; Kagan, RM; Mitsuya, Y; Shafer, RW; Shahriar, R; Varghese, V | 1 |
Chen, YC; Dumond, JB; Fiscus, SA; Horton, AL; Kashuba, AD; Patterson, KB; Rezk, NL; Tappouni, HL; Tien, HC; Vourvahis, M; Yeh, RF | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N | 1 |
Baba, M; Cheng, YC; Dutschman, GE; Grill, SP; Hamasaki, T; Paintsil, E; Tanaka, H; Wang, CJ; Wang, J; Yang, G | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
Almond, MR; Buckheit, RW; Hartman, T; Keilholz, L; Lampert, BM; Lanier, ER; Mankowski, MK; Osterling, MC; Painter, GR; Ptak, RG | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Balestrieri, E; Chiacchio, MA; Ferlazzo, A; Giofrè, SV; Iannazzo, D; Macchi, B; Mastino, A; Piperno, A; Pizzimenti, F; Romeo, R | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Bassit, L; Coats, SJ; Detorio, M; Herman, BD; Mellors, JW; Nettles, JH; Obikhod, A; Schinazi, RF; Sluis-Cremer, N; Solomon, S; Tao, SJ; Zhang, HW | 1 |
Hamburger, M; Hamy, F; Klimkait, T; Louvel, S; Mojarrab, M; Potterat, O; Sanglier, JJ; Vidal, V | 1 |
Agarwal, HK; Chhikara, BS; Doncel, GF; Parang, K; Quiterio, M | 1 |
Agarwal, HK; Buckheit, KW; Buckheit, RW; Parang, K | 1 |
Chavre, SN; Chu, CK; Govindarajan, R; Hung, W; Korba, B; Rawal, RK; Singh, US; Sugiyama, M; Tanaka, Y; Wang, J | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Balzarini, J; Bourdin, C; Chamberlain, S; Derudas, M; Hamon, N; Hinsinger, K; Introini, A; Kandil, S; Kolykhalov, A; Madela, K; Margolis, L; McGuigan, C; Meneghesso, S; Pertusati, F; Serpi, M; Slusarczyk, M; Vanpouille, C; Vernachio, J | 1 |
Chen, FE; Chen, WX; De Clercq, E; He, QQ; Pannecouque, C; Piao, HR; Wu, HQ; Wu, Y; Yan, ZH | 1 |
Costa, J; Dumontet, V; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Retailleau, P; Roussi, F | 1 |
Balzarini, J; Chen, F; Chen, W; De Clercq, E; Liu, Y; Meng, G; Pannecouque, C; Zheng, A | 1 |
Chen, W; De Clercq, E; Liu, X; Liu, Z; Pannecouque, C; Zhan, P | 1 |
Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yao, J | 1 |
Balzarini, J; Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Yu, M; Zhan, P | 1 |
Ashok, P; Balzarini, J; Chander, S; Murugesan, S; Pannecouque, C | 1 |
Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Li, X; Liang, X; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Zhan, P | 1 |
Girard-Valenciennes, E; Grondin, I; Leyssen, P; Litaudon, M; Neyts, J; Olivon, F; Palenzuela, H; Pannecouque, C; Roussi, F | 1 |
Arumugam, SR; Badri, KR; He, JJ; Visalli, RJ; Zhang, X; Zhao, H; Ziobrowski, H | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Gray, LR; Hammarskjold, ML; Rekosh, D; Santos, WL; Tebit, DM; Wynn, JE; Zhang, W | 1 |
Bhatt, HG; Pannecouque, C; Patel, BD; Patel, SB | 1 |
Chen, W; Daelemans, D; De Clercq, E; Huang, B; Liu, X; Pannecouque, C; Yang, J; Zhan, P | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
Daelemans, D; De Clercq, E; Ding, X; Fang, Z; Huang, B; Kang, D; Li, Z; Liu, X; Lu, X; Pannecouque, C; Xu, H; Zhan, P; Zhang, H; Zhou, Z | 1 |
Agarwal, HK; Chhikara, BS; Doncel, GF; Parang, K | 1 |
Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R | 1 |
Chen, FE; Gu, SX; Liu, GY; Meng, G; Pannecouque, C; Tang, JF; Wu, FS; Xiao, T; Xu, ZQ; Zhu, YY | 1 |
Cherukupalli, S; De Clercq, E; Feng, D; Fu, Z; Jiang, X; Kang, D; Liu, X; Pannecouque, C; Wang, Z; Zhan, P | 1 |
De Clercq, E; Huang, B; Jiang, X; Kang, D; Li, J; Liu, X; Olotu, FA; Pannecouque, C; Soliman, MES; Wang, Z; Zhan, P | 1 |
Chen, FE; De Clercq, E; Jin, X; Pannecouque, C; Piao, HR; Zhuang, C | 1 |
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
Cannon, D; Furman, PA; Lloyd, RM; Mathis, R; McMillan, A; Peck, A; Schinazi, RF; Sommadossi, JP; St Clair, M; Wilson, J | 1 |
Boehme, RE; Cameron, JM; Cammack, N; Coates, JA; Marr, CL; Penn, CR; Reid, PJ; Rouse, P | 1 |
Beach, JW; Cannon, D; Choi, WB; Chu, CK; Jeong, LS; Mathis, R; McMillan, A; Peck, A; Schinazi, RF; Yeola, S | 1 |
Cameron, JM; Cammack, N; Coates, JA; Jenkinson, HJ; Jowett, AJ; Jowett, MI; Pearson, BA; Penn, CR; Rouse, PL; Viner, KC | 1 |
Gao, Q; Li, XG; Parniak, MA; Rooke, R; Soudeyns, H; Tremblay, M; Wainberg, MA; Yao, XJ | 1 |
Belleau, B; Gao, Q; Kraus, JL; Nguyen-Ba, N; Soudeyns, H; Spira, B; Wainberg, MA; Yao, XI | 1 |
Portegies, P | 1 |
Benoit, SL; Eron, JJ; Fallon, MA; Jemsek, J; Kuritzkes, DR; MacArthur, RD; Quinn, JB; Rubin, M; Santana, J | 1 |
Merigan, TC | 1 |
Mitsuya, H | 1 |
Cameron, J; Fang, H; Gao, Q; Goldberg, E; Gu, Z; Parniak, MA; Salomon, H; Wainberg, MA | 1 |
Belmonte, A; Gelfand, M; Gu, Z; Nguyen, K; Salomon, H; Wainberg, MA | 1 |
Beardsley, T | 2 |
Harrigan, PR; Kemp, SD; Larder, BA | 1 |
Barry, DW; Pennington, KN; Rooney, J; St Clair, MH | 1 |
Faust, EA; Gao, Q; Gu, Z; Wainberg, MA | 1 |
Gunnarsson, G; Hammer, SM | 1 |
Kemp, SD; Larder, BA; Parry, NR; Tisdale, M | 1 |
Dudley, MN | 1 |
Cohen, J | 3 |
Balzarini, J | 1 |
Costigliola, P; Degrassi, A; Facchini, A; Lisignoli, G; Monaco, MC; Ricchi, E; Toneguzzi, S | 1 |
Arts, EJ; Boulerice, F; Geleziunas, R; Goldman, H; Wainberg, MA | 1 |
Arts, EJ; Gu, Z; Le Grice, SF; Marois, JP; Wainberg, MA | 1 |
Brenner, B; Lalonde, R; Mercure, L; Phaneuf, D; Wainberg, MA | 1 |
Hui, F; Kavlick, MF; Kojima, E; Mitsuya, H; Pluda, JM; Shirasaka, T; Yarchoan, R | 1 |
Gataric, N; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Schechter, MT; Yip, B | 1 |
Staszewski, S | 3 |
Danner, SA; Dellarnonica, P; Harrigan, PR; Hill, AM; Johnson, MA; Loveday, C; McDade, H; Picazo, JJ; Skinhøj, P; Staszewski, S; Verity, L | 1 |
Clumeck, N; Hill, AM; Ingrand, D; Johnson, M; Katlama, C; Loveday, C; Mallolas, J; McDade, H; Pearce, G; Staszewski, S | 1 |
Bartlett, JA; Benoit, SL; Ehmann, WC; Fallon, MA; Johnson, VA; Quinn, JB; Rubin, M; Self, PL; Sepulveda, GE; Tsoukas, C | 1 |
Rowe, PM | 1 |
Costes, O; Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C | 1 |
Bloor, S; Harrigan, PR; Kemp, SD; Kinghorn, I; Kohli, A; Larder, BA; Nájera, I | 1 |
Andries, K; De Brabander, M; De Crée, J; De Raeymaeker, M; Miller, V; Moeremans, M; Pearce, G; Peeters, M; Rehmet, S; Stark, T; Staszewski, S; Stoffels, P; Van den Broeck, R; Verbiest, W | 1 |
Back, DJ; Barry, MG; Hoggard, PG; Khoo, S; Veal, GJ | 1 |
Gerberding, JL | 1 |
Costes, O; Djediouane, A; Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C | 1 |
Chikami, GK; Piazza-Hepp, TD; Styrt, BA | 1 |
Lane, HC; Masur, H; Spooner, KM | 1 |
Coen, DM | 1 |
Bartlett, JA; Eron, JJ; Hill, AM; Johnson, J; Phillips, AN; Price, S; Rubin, M; Self, P | 1 |
Bakhtiari, M; Benoit, SL; Eron, JJ; Fallon, MA; Griffin, A; Kuritzkes, DR; Poticha, D; Quinn, JB; Rubin, M; Shugarts, DL | 1 |
Slavkin, HC | 1 |
Faulds, D; Lea, AP | 1 |
Schattner, A | 1 |
Cameron, JM; Cammack, N; Goulden, MG; Hopewell, PL; Penn, CR | 1 |
Mörike, EM | 1 |
Carr, A; Cooper, DA; Emery, S; Kelleher, A; Law, M | 1 |
Balagué, M; Cabrera, C; Clotet, B; De Clercq, E; Martínez-Picado, J; Puig, T; Romeu, J; Ruiz, L; Schmit, JC; Segura, A; Sirera, G; Tural, C; Vandamme, AM | 1 |
Boucher, CA; De Boer, RJ; De Jong, MD; Schuurman, R; Stilianakis, NI; Van Leeuwen, R | 1 |
Berkhout, B; Boucher, C; Keulen, W; Nijhuis, M; Schuurman, R | 1 |
Patrick, DM | 1 |
Cox, S; Palmer, S | 1 |
Bartlett, J; Eron, J; Gilbert, C; Hill, AM; Johnson, J; Johnson, VA; Keller, A; Kuritzkes, DR; Phillips, AN | 1 |
Lafeuillade, A; Pellegrino, P; Poggi, C; Profizi, N; Sayada, C | 1 |
Back, D; Barry, M; Gibbons, S; Merry, C; Mulcahy, F | 1 |
Eron, JJ | 1 |
Stephenson, J | 1 |
Belohradsky, BH; Eberle, J; Gürtler, L; Notheis, G; Sölder, B; Wintergerst, U | 1 |
Aguirrebengoa, K; Mallolas, J; Torres Tortosa, M; Uriz, J | 1 |
Bonhoeffer, S; Coffin, JM; Nowak, MA | 1 |
Bawdon, RE; Bloom, SL; Dias, KM; Gilstrap, LC | 1 |
Macready, N | 1 |
Baba, M; Nakade, K; Piras, G; Yuasa, S | 1 |
Bartlett, J; Eron, JJ; Hill, AM; Johnson, J; Katlama, C; McDade, H; Sawyer, W; Staszewski, S | 1 |
Hirschel, B; Rutschmann, O | 1 |
Back, DJ; Barry, MG; Khoo, SH; Veal, GJ | 1 |
Boulton, A | 1 |
Heins, JR | 1 |
Iversen, AK; Merigan, TC; Shafer, RW; Winters, MA | 1 |
Costes, O; Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C; Tourres, C | 1 |
Cavert, W; Danner, SA; Gebhard, K; Goudsmit, J; Haase, AT; Henry, K; McDade, H; Mills, R; Notermans, DW; Schuwirth, CM; Staskus, K; Wietgrefe, SW; Zhang, ZQ; Zupancic, M | 1 |
Cao, Y; Essunger, P; Ho, DD; Hurley, A; Markowitz, M; Perelson, AS; Saksela, K; Vesanen, M | 1 |
Costello, CE; Nelson, MR; Walsh, JC | 1 |
Ohta, Y; Shinkai, I | 1 |
Jacobson, MA; O'Donnell, JJ; Owens, S; Pavan, PR; Pollard, R; Rao, N; Sattler, F; Zegans, M | 1 |
Eisen, JA; Katzenstein, DA; Merigan, TC; Shafer, RW | 1 |
Fantini, J; Lafeuillade, A; Poggi, C; Tamalet, C; Yahi, N | 1 |
Wainberg, MA | 1 |
Bader, JP; Buckheit, RW; Gussio, R; Pallansch, L; Pattabiraman, N; Yang, SS | 1 |
Ahle, D; Bushnell, S; Chang, C; Collins, ML; Detmer, J; Fine, E; Ho, DD; Horn, T; Irvine, B; Kolberg, J; Shen, LP; Tyner, D; Urdea, MS; Zayati, C | 1 |
Böhler, T; Debatin, KM; Geiss, M; Haas, J; Herr, I | 1 |
Boucher, CA; Danner, S; de Groot, T; de Jong, D; Keulen, W; Lange, J; Nijhuis, M; Schuurman, R; van Leeuwen, R | 1 |
Collins, DO; Sakamoto, A | 1 |
Goody, RS; Immendörfer, U; Krebs, R; Thrall, SH; Wöhrl, BM | 1 |
Clavel, F; Dupont, B; Fournier, S; Moulignier, A; Pialoux, G; Poveda, JD | 1 |
Chenoweth, CE; Gobetti, JP | 1 |
Balfour, HH; Chodakewitz, JA; Currier, JS; Demeter, LM; Deyton, LR; Eron, JJ; Feinberg, JE; Fischl, MA; Grimes, JM; Hammer, SM; Hughes, MD; Squires, KE | 1 |
Chodakewitz, JA; Emini, EA; Eron, JJ; Gonzalez, C; Gulick, RM; Havlir, D; Jonas, L; McMahon, D; Meibohm, A; Mellors, JW; Richman, DD; Valentine, FT | 1 |
Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C | 1 |
Bulgheroni, E; Citterio, P; d'Arminio-Monforte, A; De Pasquale, MP; Galli, M; Kurtagic, S; Milazzo, L; Rusconi, S | 1 |
Escribano Hernández, A | 1 |
Gómez-Cano, M; Holguín, A; Mas, A; Soriano, V; Villalba, N | 1 |
Back, DJ; Barry, MG; Hoggard, PG; Kewn, S; Veal, GJ | 1 |
Feingold, A; Meislich, D; Rudy, B; Rutstein, RM; Word, B | 1 |
Cottalorda, J; Lefbvre, JC; Mariani, R; Monpoux, F; Sirvent, N | 1 |
Emini, E; Günthard, HF; Haase, AT; Havlir, DV; Ignacio, CC; Kwok, S; Richman, DD; Wong, JK; Zhang, ZQ | 1 |
Balzarini, J; De Clercq, E; Kleim, JP; Pelemans, H; Riess, G; Roesner, M; Winkler, I | 2 |
Günthard, HF; Havlir, DV; Hezareh, M; Ignacio, CC; Richman, DD; Spina, CA; Wong, JK | 1 |
Böhlen, L; Braathen, LR; Furrer, H; Hurni, MA | 1 |
Baba, M; Makino, M; Piras, G | 1 |
Izopet, J; Marchou, B; Massip, P; Pasquier, C; Puel, J; Sandres, K; Tamalet, C | 1 |
Hauri, D; John, H; Müller, NJ; Opravil, M | 1 |
Gisslén, M; Hagberg, L; Norkrans, G; Svennerholm, B | 1 |
Alaeus, A; Albert, J; Cox, S; Palmer, S | 1 |
Goldstein, H; Katopodis, NF; Kim, A; Kollmann, TR; Pettoello-Mantovani, M; Raker, C; Wiltshire, H; Yurasov, S | 1 |
Edelstein, RE; Frenkel, LM; Manns-Arcuino, LA; Nickerson, DA; Tobe, VO | 1 |
Cavert, W; Danner, SA; de Jong, JJ; de Wolf, F; Foudraine, NA; Goodwin, C; Goudsmit, J; Jurriaans, S; Kauffmann, RH; Leonard, JM; McDade, H; Meenhorst, PL; Notermans, DW; Schuwirth, CM | 1 |
Chapanduka, ZC; Matchaba, PT | 1 |
Back, DJ; Barry, MG; Hoggard, PG; Manion, V | 1 |
Collins-Jones, TL; Davis, KF; Farley, JJ; Houck, DL; Rothman, MI; Tepper, VJ; Wachtel, RC | 1 |
Barton, S; Blaxhult, A; Clotet, B; Goebel, FD; Hirschel, B; Katlama, C; Lundgren, JD; Pedersen, C; Phillips, AN; Vella, S | 1 |
North, TW; Preston, BD; Remington, KM; Schinazi, RF; Smith, RA | 1 |
Guatelli, JC; Günthard, HF; Havlir, DV; Ignacio, CC; Richman, DD; Riggs, NL; Wong, JK | 1 |
Beuers, U; Mühlhöfer, A; Samtleben, W; Thoenes, GH; von Appen, K; Weiss, M | 1 |
Gómez-Cano, M; Soriano, V | 1 |
Conway, B; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Rhone, SA; Schechter, MT; Sherlock, C; Yip, B | 1 |
Hester, EK; Peacock, JE | 1 |
DeMasi, R; Hill, AM; Montaner, JS | 1 |
Adams, O; Horneff, G; Wahn, V | 1 |
Ortega-Larrocea, G; Rutzen, AR; Tanguilig, GG | 1 |
Koopmans, PP; ter Hofstede, HJ; van Haelst, UJ | 1 |
Boswell, SL | 1 |
Bloor, S; Harrigan, PR; Kemp, SD; Larder, BA; Mellors, JW; Shi, C | 1 |
Gray, CM; Merigan, TC; Schapiro, JM; Winters, MA | 1 |
Clement, JG; Pardridge, WM; Wu, D | 1 |
Bai, J; Daar, ES; Giorgi, JV; Hausner, MA; Majchrowicz, M; Tamaddon, M | 1 |
Burt, MS; Mills, RJ; Scott-Lennox, JA | 1 |
Bloor, S; de Béthune, MP; Harrigan, PR; Hertogs, K; Kemp, SD; Larder, BA; Miller, V; Pauwels, R; Phillips, A; Rottmann, C; Staszewski, S | 1 |
Stevens, TP; Watson, WJ; Weinberg, GA | 1 |
Blanchard, G; Blum, L; Calvo, F; Danne, O; Lebbé, C; Morel, P; Pellet, C; Vérola, O | 1 |
Bloor, S; de Béthune, MP; Gröschel, B; Harrigan, PR; Hertogs, K; Kemp, SD; Larder, BA; Miller, V; Pauwels, R; Staszewski, S; Stürmer, M | 1 |
Aboulker, JP; Batisse, D; Belec, L; Castiel, P; Gilquin, J; Gonzalez-Canali, G; Jayle, D; Karmochkine, M; Kazatchkine, MD; Piketty, C; Si Mohamed, A; Weiss, L | 1 |
Batisse, D; Belec, L; Karmochkine, M; Kazatchkine, MD; Piketty, C; Si Mohamed, A | 1 |
Duchatelle, V; Durand, F; Hermine, O; Karras, A; Rabian, C; Valla, D; Viard, JP; Zylberberg, H | 1 |
Kaiser, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Theisen, A | 1 |
Kahn, JG; Marseille, E; Saba, J | 1 |
Balis, FM; Brouwers, P; Deutsch, PJ; Jarosinski, PF; Ju, W; Mistry, G; Mueller, BU; Nelson, RP; Pizzo, PA; Sei, S; Sleasman, J; Smith, S; Steinberg, SM; Winchell, G; Wood, LV; Zeichner, S; Zwerski, S | 1 |
Dalod, M; Deschemin, JC; Dumon, B; Gomard, E; Harzic, M; Hoen, B; Levy, JP; Pellegrin, I; Sereni, D; Venet, A | 1 |
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Carrington, M; Havlir, DV; Ioannidis, JP; McDermott, DH; Murphy, PM; O'Brien, TR; Richman, DD | 1 |
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Carr, RM; Dunn, JA; Kenney, KB; Wells, GN; Wring, SA | 1 |
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Aladdin, H; Dickmeiss, E; Gerstoft, J; Hede, A; Jørgensen, LB; Katzenstein, TL; Nielsen, C; Nielsen, H | 1 |
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Cohen, MS; Dunn, JA; Eron, JJ; Hall, JE; Kenney, KB; Pereira, AS; Tidwell, RR | 1 |
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Gartland, M; Harrigan, R; Hill, A; Kleim, JP; Maguire, M; Moore, S; Tisdale, M | 1 |
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Collier, AC; Havlir, DV; Hirsch, MS; Ioannidis, JP; Richman, DD; Tebas, P | 1 |
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Bamberger, JD; Hirozawa, A; Katz, MH; Kimmerling, R; Myles, JE | 1 |
Neto, JL; Siciliano, RF | 1 |
Albrecht, MA; Balfour, HH; Hammer, SM; Hughes, MD; Katzenstein, DA; Liou, SH; Murphy, R; Para, MF; Valdez, H | 1 |
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García, H; Rodriguez, JF; Rodriguez, JL; Rosario, O; Santana, J | 1 |
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La Seta Catamancio, S; Parker, D; Rusconi, S; Sheridan, F | 1 |
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Kuritzkes, DR; Landay, AL; Lederman, MM; Mosier, DE; Picchio, GR; Sabbe, R; Valdez, H | 1 |
Allen, DY; Carlan, S; Cu-Uvin, S; Dobles, AR; Garb, J; Harwell, JI; Jones, TB; Morris, AB; Vajaranant, M; Zorrilla, C | 1 |
Fiore, TC; Tashima, KT | 1 |
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Darque, A; Moore, JD; Sommadossi, JP; Valette, G; Zhou, XJ | 1 |
Ceballos-Garcia, L; Ceballos-Salobreña, A; Gaitán-Cepeda, LA; Lezama-Del Valle, D | 1 |
Acosta, EP; Anderson, PL; Brundage, RC; Fletcher, CV; Henry, K; Kakuda, TN; Page, LM; Rhame, FS; Schacker, TW | 1 |
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Busch, M; Hecht, FM; Kahn, J; Levy, JA; Martinez-Marino, B; Ong, JC; Stranford, SA | 1 |
Fernandez, AD; McNeeley, DF | 1 |
Henney, JE | 1 |
Acosta, EP; Collier, AC; Havlir, DV; Hirsch, M; Richman, DD; Sommadossi, JP; Tebas, P; Zhou, XJ | 1 |
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Kerr, C | 1 |
Clotet, B; Del Romero, J; Leal, M; Pérez-Olmeda, M; Rodríguez, C; Rubio, A; Ruiz, L; Soriano, V | 1 |
Airoldi, M; Carosi, G; Castelli, F; Patroni, A; Quiros-Roldan, E; Signorini, S; Torti, C | 1 |
Bellman, PC; Fisher, RL; Henry, K; Liao, Q; Norris, D; Ross, LL; Shaefer, MS; Wallace, RJ | 1 |
Dworkin, MS; Wan, PT | 1 |
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Bamberger, JD; Chambers, D; Chesney, M; Coates, TJ; Franses, K; Kahn, JO; Katz, MH; Martin, JN; Roland, ME | 1 |
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Carr, A; Cooper, DA; Cunningham, PH; Goh, LE; Grey, P; Kaufmann, GR; Smith, D; Suzuki, K; Zaunders, JJ | 1 |
Bottasso, OA; Giovannoni, AG; Luraghi, MR; Montero, A; Sen, L | 1 |
Thompson, CA | 1 |
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Citterio, P; De Pasquale, MP; Galli, M; Kurtagic, S; La Seta Catamancio, S; Rusconi, S | 1 |
Achilli, G; Bruno, R; Debiaggi, M; Filice, G; Patruno, SF; Pistorio, A; Romero, E; Sacchi, P; Zara, F | 1 |
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Arendt, G; Hefter, H; Theisen, A; von Giesen, HJ | 1 |
Briones, C; del Romero, J; Hertogs, K; Pérez-Olmeda, M; Rodríguez, C; Soriano, V | 1 |
Alleva, E; Ricceri, L; Sorace, A; Valanzano, A; Venerosi, A | 1 |
Arazo, P; Manero, FJ; Sesma, J | 1 |
Loveday, C | 1 |
Allsup, TL; Hutman, HW; Lou, Y; Mahony, WB; Otto, VR; Thompson, NF; Yuen, GJ | 1 |
Fournier, S; Maillard, A; Molina, JM | 1 |
Brown, AJ; Emini, E; Eron, J; Fiscus, S; Frost, SD; Gamagami, R; Gulick, R; Günthard, HF; Haase, A; Havlir, DV; Ignacio, CC; Isaacs, R; Jonas, L; Meibohm, A; Mellors, J; Richman, DD; Schleif, W; Valentine, F; Wong, JK; Zhang, ZQ | 1 |
Clerici, M; Gray, G; Kuhn, L; Meddows-Taylor, S; Shearer, GM; Tiemessen, C; Trabattoni, D | 1 |
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Rubin, M | 1 |
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Coombs, R; Cotton, D; Hammer, S; Saag, M; van der Horst, C | 1 |
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Gellett, LR; Haddon, L; Maskell, GF | 1 |
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Funk, MB; Klingebiel, T; Kreuz, W; Linde, R; Notheis, G; Schuster, T; Wintergerst, U | 1 |
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Cohen, MS; Jordan, HL; Kashuba, AD; Pereira, AS | 1 |
Burger, DM; de Wolf, F; Foudraine, NA; Hoetelmans, RM; Jurriaans, S; Lange, JM; Maas, J; Miedema, F; Portegies, P; Reiss, P; Roos, MT; Weverling, GJ | 1 |
Chougnet, C; Fowke, K; Jankelevich, S; Liewehr, D; Mueller, BU; Pizzo, PA; Shearer, GM; Steinberg, SM; Yarchoan, R | 1 |
Danner, SA; de Boer, RJ; Goudsmit, J; Huismans, R; Jebbink, MF; Lukashov, VV | 1 |
Corzo, JE; Gómez-Mateos , J; Lozano, F; Ramayo, E | 1 |
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Gartland, M | 1 |
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Machuca, A; Rodés, B; Soriano, V | 1 |
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Bartlett, JG; del Rio, C | 1 |
MacGowan, DJ; Scelsa, SN; Waldron, M | 1 |
Chadapaud, S; Halfon, P; Hittinger, G; Khiri, H; Lafeuillade, A; Poggi, C | 1 |
Anderson, R; Chapman, SK; Clendeninn, N; Conant, M; Myers, R; Saag, MS; Sension, M; Tebas, P | 1 |
Duan, C; Kuritzkes, DR; McHenry, CS; Petropoulos, CJ; Poticha, D; Stoeckli, TC; Whitcomb, JM | 1 |
Bisset, LR; Böni, J; Hofmann-Lehmann, R; Lüthy, R; Lutz, H; Schüpbach, J | 1 |
Haase, CP; Hoit, BD; Lewis, W; Raidel, SM; Russ, RB; Samarel, AM; Sutliff, RL | 1 |
Akanmu, AS; Akinsete, I; Davies, AO; Eshofonie, AO; Okany, CC | 1 |
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Korn, K; Schmidt, B; Schwingel, E; Walter, H; Werwein, M | 1 |
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Jaccard, R; Jenni, R; Opravil, M; Speich, R | 1 |
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Anderson, PL; Brundage, RC; Fletcher, CV; Gross, CR; Henry, K; Kakuda, TN; Schacker, TW | 1 |
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Arai, M; Earl, DD; Yamamoto, JK | 1 |
Stekelenburg, J | 1 |
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de Wolf, F; Jurriaans, S; Lange, JM; Prins, JM; van Praag, RM; Wit, FW | 1 |
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Conrad, F; Govender, M; Maartens, G; Manning, K; Papavarnavas, NS | 1 |
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Chow, SC; Yuan, M; Zheng, J | 1 |
Awoke, T; Birlie, B; Braekers, R; Kasim, A; Shkedy, Z | 1 |
Barrow, G; Camacho, R; Carmona, S; Grant, PM; Gupta, RK; Hamers, RL; Harrigan, PR; Jordan, MR; Kantor, R; Katzenstein, DA; Kuritzkes, DR; Maldarelli, F; Otelea, D; Paredes, R; Schapiro, JM; Shafer, RW; Tzou, PL; van Zyl, G; Wallis, CL | 1 |
Andolina, A; Carbone, A; Castagna, A; Franzin, M; Galizzi, N; Galli, L; Gianotti, N; Lazzarin, A; Merli, M; Muccini, C; Oltolini, C; Poli, A; Spagnuolo, V; Tadini, P | 1 |
Brambilla, D; Ceffa, S; De Luca, A; Liotta, G; Luhanga, R; Magid, NA; Mancinelli, S; Marazzi, MC; Palombi, L; Sidumo, ZJ; Zanelli, G | 1 |
Agarwal, A; Alexander, PE; Chang, Y; Foroutan, F; Guyatt, GH; Hepworth, E; Lee, Y; Lesi, O; Mah Ming, J; Merglen, A; Mir, H; Mirza, R; Siemieniuk, RA; Zeraatkar, D; Zhang, Y | 1 |
Contreras-Galindo, R; Dube, D; Fujinaga, K; Kaplan, MH; Markovitz, DM | 1 |
Abalem, MF; Carricondo, PC; Rao, RC | 1 |
Alzate Angel, JC; Duque Molina, MM; García García, HI | 1 |
Akunuri, S; Kallampallil, J; Leong, S; Maweni, R | 1 |
Aroke, D; Bechem, NN; Dimala, CA; Kadia, BM | 1 |
Ahmadi, NE; Ahsani-Nasab, S; Bayanolhagh, S; Esmaeilzadeh, A; Lolaie, M; Moallemi, S; Mohraz, M; Narouei, A; Sadeghi, L; SeyedAlinaghi, S; Tabatabai, RA | 1 |
Domínguez-Castro, M; Figueroa-Damián, R; Flores-García, Z; Hernández-Pineda, J; Loaiza-Flores, G; López-Martínez, M; Plazola-Camacho, N; Ramírez-Ramírez, A; Rodríguez-Delgado, RG; Sánchez-Serrano, E | 1 |
Awodele, O; Oshikoya, KA; Popoola, TD | 1 |
Castelnuovo, B; Gonza, P; Kambugu, A; Kiragga, AN; Mbabazi, O; Mubiru, F; Musomba, R; Ratanshi, RP | 1 |
Bourrel, R; Lapeyre-Mestre, M; Montastruc, JL; Rwagitinywa, J; Sommet, A | 1 |
Drosu, NC; Edelman, ER; Housman, DE | 1 |
Fatma, S; Jaiswal, S; Prasad, BB; Singh, K; Singh, R | 1 |
Barr, E; Chadwick, EG; Currier, JS; Hernandez-Diaz, S; Hoffman, RM; Huo, Y; Patel, K; Rough, K; Seage, GR; Shapiro, DE; Williams, PL | 1 |
Antony, J; Ashoor, HM; Blondal, E; Finkelstein, Y; Ghassemi, M; Gough, K; Hemmelgarn, BR; Hutton, B; Ivory, JD; Khan, PA; Lillie, E; Straus, SE; Tricco, AC; Vafaei, A; Veroniki, AA | 1 |
Desai, M; Dinh, C; Gonzalez, R; Haaland, RE; Heneine, W; Katana, A; Martin, A; Menendez, C; Otieno, K; Slutsker, L; Williamson, J | 1 |
Cunha, KS; de Souza, AP; Dihl, RR; Grando, AC; Guimarães, NN; Lehmann, M | 1 |
Adeyeye, CM; Ali, I; Aliu, R; Awodele, O; Oni, Y | 1 |
Mugusi, S; Ngaimisi, E; Sasi, P; Sungi, SS; Ulenga, N | 1 |
Behrens, GMN; Budida, R; Hegermann, J; Lin, H; Panayotova-Dimitrova, D; Schmidt, RE; Stankov, MV | 1 |
Bailão, E; Cardoso, CG; Chen-Chen, L; Cunha, KS; de Jesus Silva Carvalho, C; de Moraes Filho, AV; Spanó, MA; Véras, JH | 1 |
de Oliveira, MA; Franco, JB; Martins E Martins, F; Maureira Pena, LJ; Ortega, KL | 1 |
Kan, W; Leng, X; Liao, L; Liu, P; Ruan, Y; Shao, Y; Wang, J; Xing, H; Xu, W; Yan, J; You, Y; Zuo, Z | 1 |
Abdoul, H; Baek, J; Barnerias, C; Barth, M; Belot, A; Blanche, S; Boddaert, N; Bondet, V; Bouazza, N; Cances, C; Crow, YJ; Debray, FG; Desguerre, I; Doummar, D; Duffy, D; Frémond, ML; Henry, E; Hully, M; Jolaine, V; Kitabayashi, N; Lepelley, A; Levrat, V; Llibre, A; Melki, I; Meyer, P; Meyzer, C; Nougues, MC; Renaldo, F; Rice, GI; Rodero, MP; Rodriguez, D; Roubertie, A; Rozenberg, F; Sambe, MN; Seabra, L; Semeraro, M; Treluyer, JM; Uggenti, C; Zeef, LAH | 1 |
Chasela, CS; Corbett, A; Davis, NL; Hudgens, MG; Jamieson, DJ; Kaullen, J; Kourtis, AP; Miller, WC; Nelson, JAE; Sichali, D | 1 |
Agyingi, K; Domkam, I; Joyce, AN; Keou, CK; Mbu, RE; Moudourou, S; Nanfack, A; Njefi, K; Sosso, S; Takang, W; Takou, D; Torimiro, JN | 1 |
Bettencourt da Silva, RJN; Lourenço, FR | 1 |
Chendi, BH; Eyoh, A; Ikomey, GM; Jacobs, GB; Lyonga, E; Mesembe, M; Okomo Assoumou, MC; Yekwa, EL | 1 |
Huang, JP; Huang, WH; Luo, SD; Luo, XL; Mo, LD; Ni, ZY; Su, GS; Su, HZ; Wu, JY | 1 |
Aizire, J; Boivin, MJ; Familiar-Lopez, I; Fowler, MG; Kawalazira, R; Kuteesa, A; Maliwichi-Senganimalunje, L; Mallewa, M; Mutebe, A; Namukooli, JL; Nyakato, M; Ogwang, LW; Ruiseñor-Escudero, H; Sikorskii, A; Taha, TE | 1 |
Anugulruengkitt, S; Chokephaibulkit, K; Cressey, TR; Jantarabenjakul, W; Ounchanum, P; Pancharoen, C; Punnahitanon, S; Puthanakit, T; Sophonphan, J; Srirompotong, U; Suntarattiwong, P | 1 |
Adebisi, SA; Adedeji, NO; Adedeji, TA | 1 |
Chen, IT; Chen, JK; Chen, YS; Lee, SS; Sy, CL; Tsai, HC; Tseng, YT; Weng, YW; Wu, KS | 1 |
Barros Silva, LCPB; da Silva, RMF; de Lima, LG; de Medeiros, FPM; de Sousa, ALMD; Lavra, ZMM; Neto, PJR; Rolim, LA; Rosa, TA; Wanderley Sales, VA | 1 |
Baijnath, S; Govender, T; Kruger, HG; Mdanda, S; Naicker, T; Ntshangase, S; Singh, SD | 1 |
Bela, B; Ibrahim, F; Kusumaningrum, A; Yunihastuti, E | 1 |
Chadwick, EG; Correia, KF; Crowell, CS; DiPerna, A; Hazra, R; Seage, GR; Smith, R; Van Dyke, RB; Williams, PL; Yildirim, C | 1 |
Chi, BH; Fairlie, L; Farhad, M; Fenton, T; Fowler, MG; Moodley, D; Naik, S; Nakabiito, C; Stringer, JSA; Venkatesh, KK | 1 |
Chen, J; Chen, X; Niu, J; Wang, J; Xie, Q; Zhou, C | 1 |
Fischer, A; Gumede, SB; Lalla-Edward, ST; Venter, WDF | 1 |
Ajibola, G; Batlang, O; Bennett, K; Capparelli, EV; Hughes, MD; Jean-Philippe, P; Kuritzkes, DR; Lichterfeld, M; Lockman, S; Makhema, J; Maswabi, K; Mohammed, T; Moyo, S; Sakoi, M; Shapiro, RL | 1 |
George, PE; Mercedes, R; Nabukeera-Barungi, N; Otto, SBJ | 1 |
Teshale, AB; Tsegaye, AT; Wolde, HF | 1 |
An, M; Ding, H; Han, X; Li, S; Ouyang, J; Wang, L; Zhang, M; Zhao, B | 1 |
Dollfus, C; Lemoine, A; Michot, J; Tounian, P; Viala, J | 1 |
Jiang, F; Lu, Z; Su, Q; Tang, Y; Wei, S; Zhou, Z | 1 |
Ebeshi, BU; Elei, S; Kashimawo, AJ; Orubu, S; Soyinka, JO; Vaikosen, EN | 1 |
Amzal, B; Cressey, TR; Jarupanich, T; Jourdain, G; Kanjanavikai, P; Klinbuayaem, V; Koetsawang, S; Lallemant, M; Le Coeur, S; Ngo-Giang-Huong, N; Rawangban, B; Sabsanong, P; Siriwachirachai, T; Sripan, P; Urien, S; Wanasiri, P | 1 |
Azmi, M; Baber, ZU; Badlani, S; Dodani, SK; Nasim, A; Sheerani, M | 1 |
Anthony, P; Best, BM; Cahn, P; Chakhtoura, N; Chokephaibulkit, K; Cressey, TR; de Lourdes B Teixeira, M; Essack, Z; Frenkel, LM; Fuller, TL; Gouvèa, MIS; Hennessy, R; João, EC; Laimon, L; Mathiba, R; Mirochnick, M; Mmbaga, BT; Moreira, LF; Morrison, RL; Ngocho, JS; Njau, BN; Pilotto, JHS; Prommas, S; Rolon, MJ; Shapiro, DE; Siberry, GK; Violari, A; Werarak, P | 1 |
Domínguez-Castro, M; Figueroa-Damián, R; Galindo-Sevilla, N; Hernández-Pineda, J; Irles, C; Jung-Cook, HH; Katende-Kyenda, NL; Ramírez-Ramírez, A; Romo-Yañéz, J | 1 |
Eggers, C; Hoetelmans, R; Läer, S | 1 |
Abdool Karim, Q; Dawood, H; Mansoor, LE; Matten, D; Naicker, CL; Naidoo, K; Singo, D; Williamson, C | 1 |
Jianwei, L; Menghua, W; Qinwei, Y; Xin, Z; Yu, Z | 1 |
Batra, H; Chawla, H; Das, BK; Hussain, AW; Kabra, SK; Katpara, S; Kumar, S; Lodha, R; Luthra, K; Singh, R; Singh, S | 1 |
Bae, J; Cook, RL; Delcher, C; Francois, K; Joseph, N; Pessoa-Brandão, L; Puttkammer, N; Rich, SN; Robin, E; Yaghjyan, L | 1 |
Aweeka, F; Bradford, S; Browning, R; Coletti, A; Costello, D; Graham, B; Hughes, E; Kamthunzi, P; Kawalazira, R; Mmbaga, BT; Moye, J; Musoke, P; Nathoo, K; Norman, J; Owor, M; Purdue, L; Reding, C; Tierney, C; Whalen, ME; Wiesner, L; Ziemba, L | 1 |
Basu, A; Biswas, A; Das, BK; Nischal, N; Soneja, M; Sood, R; Wig, N | 1 |
Boivin, MJ; Ezeamama, AE; Giordani, B; Musoke, PM; Sikorskii, A; Tuke, R; Zalwango, SK | 1 |
Benamor Teixeira, ML; Chakhtoura, N; Coombs, RW; Frenkel, LM; Fuller, TL; Gouvêa, MI; Hennessey, R; João, EC; Mirochnick, M; Morrison, RL; Shapiro, DE; Whitson, K | 1 |
Boyer, PL; Caplan, MR; Clark, P; Dewar, R; Ferris, AL; Hughes, SH; Johnson, A; Maldarelli, F; Mican, J; Rehm, CA; Sneller, MC | 1 |
Bhatt, N; Couto, A; Cuco, RM; Degomme, O; Juga, A; Loquiha, O; Meggi, B; Osman, N; Sevene, E; Sidat, M; Temermam, M; Vubil, A | 1 |
Egger, M; Goldstein, F; Hauser, A; Kouyos, RD; Reichmuth, ML; Riou, J; Wandeler, G | 1 |
Awadu, JE; Coventry, A; Ezeamama, AE; Giordani, B; Sikorskii, A; Zalwango, S | 1 |
Avihingsanon, A; Azwa, I; Chaiwarith, R; Chan, YJ; Choi, JY; Ditangco, R; Do, CD; Gani, YM; Huy, BV; Jiamsakul, A; Khusuwan, S; Kiertiburanakul, S; Kim, JH; Kumarasamy, N; Lee, MP; Ly, PS; Merati, TP; Ng, OT; Pujari, S; Ross, J; Tanuma, J; Yunihastuti, E; Zhang, F | 1 |
Asienzo, J; Ategeka, G; Balyegisawa, A; Borok, M; Castelnuovo, B; Hoppe, A; Kaimal, A; Kambugu, A; Kiragga, A; Kityo, C; Lugemwa, A; Mirembe, G; Mugerwa, H; Musaazi, J; Odongpiny, ELA; Paton, NI; Siika, A; Walimbwa, S | 1 |
Ahmed, FO; Aning, BD; Ansah, RO; Ayisi-Boateng, NK; Enimil, AK; Ojuang, DA; Okeke, CB; Opoku, S; Sakyi, SA; Sarfo, AD; Senu, E; Wekesa, DN | 1 |
Bhattacharya, D; Butler, K; Chakhtoura, N; Currier, JS; Dula, D; Fowler, MG; George, K; Govender, V; Kiweewa, FM; Mohtashemi, N; Moodley, D; Musoke, P; Peters, MG; Ship, H; Tierney, C; Vhembo, T | 1 |
Abongwa, LE; Bella, S; Charles, F; Domkam, I; Emmanuel, N; Eyongetah, M; Jude, B; Moungang, EC; Mua, FH; Ngum, V; Nyamache, AK; Okemo, P; Tamboh, TC; Torimiro, J | 1 |
Copello, GJ; De Fino, FT; Filia, MF; Minoia, JM; Peroni, RN; Roma, MI | 1 |
Evans, D; Hans, L; Levin, L; Steegen, K; Technau, KG | 1 |
Adebisi, SA; Adedeji, NO; Adedeji, TA; Ajeigbe, AK; Ajose, AO; Akande, AA; Fawale, MB; Jeje, OA; Okesina, BA; Smith, OS | 1 |
Aghokeng, A; Ateba Ndongo, F; Bilong, S; Djeuda, ABD; Eboumbou Moukoko, CE; Eyoum Bille, B; Fokam, J; Grace, N; Koki Ndombo, P; Moukoko Mbonjo, M; Ndjolo, A; Penda, CI | 1 |
Motiee, F; Sohrabi, MR; Valaee, M | 1 |
Awadu, JE; Bovin, MJ; Ezeamama, AE; Giordani, B; Musoke, PM; Sikorskii, A; Zalwango, SK | 1 |
Chen, H; Deng, Y; Gao, Y; Ge, X; Ge, Y; Lan, G; Li, B; Li, S; Liu, S; Luo, H; Luo, L; Meng, Q; Qin, G; Qin, H; Wang, Y; Wen, P; Wu, X; Yang, H; Zhu, J; Zhu, Q | 1 |
Eleje, GU; Ikechebelu, JI; Nwagha, UI; Okafor, HU; Ugwu, AO; Ugwu, EO; Umeh, UA | 1 |
Chen, X; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Li, W; Liu, X; Meng, Q; Pannecouque, C; Zhan, P | 1 |
Chizhov, AO; Geisman, AN; Khandazhinskaya, AL; Kochetkov, SN; Naesens, L; Novikov, MS; Ozerov, AA; Pannecouque, C; Seley-Radtke, KL; Valuev-Elliston, VT | 1 |
Cherukupalli, S; De Clercq, E; Fu, Z; Gao, S; Kang, D; Liu, X; Pannecouque, C; Sun, L; Zhan, P; Zhang, T; Zhou, Z | 1 |
81 review(s) available for lamivudine and zidovudine
Article | Year |
---|---|
Natural product-based anti-HIV drug discovery and development facilitated by the NCI developmental therapeutics program.
Topics: Amino Acid Sequence; Anti-HIV Agents; HIV-1; Models, Biological; Models, Chemical; Molecular Sequence Data; National Institutes of Health (U.S.); Retrospective Studies; United States; Virus Replication | 2001 |
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
An approach to antiretroviral treatment of HIV disease. Nucleoside monotherapy.
Topics: Antiviral Agents; Didanosine; HIV Infections; HIV-1; Humans; Lamivudine; Nucleosides; Stavudine; Zalcitabine; Zidovudine | 1995 |
Clinical pharmacokinetics of nucleoside antiretroviral agents.
Topics: Animals; Didanosine; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1995 |
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.
Topics: Animals; Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; Humans; Lamivudine; Purines; Pyrimidines; Retroviridae; Spiro Compounds; Stavudine; Thymidine; Uridine; Zalcitabine; Zidovudine | 1994 |
Prophylaxis for occupational exposure to HIV.
Topics: Antiviral Agents; Health Personnel; HIV Infections; Humans; Lamivudine; Occupational Exposure; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1996 |
Clinical toxicity of antiretroviral nucleoside analogs.
Topics: Animals; Antiviral Agents; Didanosine; Humans; Lamivudine; Mitochondria; Nucleosides; Stavudine; Zalcitabine; Zidovudine | 1996 |
Guide to major clinical trials of antiretroviral therapy administered to patients infected with human immunodeficiency virus.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Meta-Analysis as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1996 |
Wheel keeps turning for antiviral combination chemotherapy.
Topics: Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Lamivudine; Virus Diseases; Zidovudine | 1996 |
Ritonavir.
Topics: Administration, Oral; Anti-HIV Agents; Biological Availability; CD4-Positive T-Lymphocytes; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Leukocyte Count; Randomized Controlled Trials as Topic; Ritonavir; RNA, Messenger; Zalcitabine; Zidovudine | 1996 |
[Nucleoside analogs inhibiting reverse transcriptase: use in adult patient with HIV infection].
Topics: Adult; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1996 |
Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments: a meta-analysis of controlled trials.
Topics: Adolescent; Adult; Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Disease Progression; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; United States; Zidovudine | 1997 |
Antiretroviral therapy: a guide to the most important trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1997 |
[Antiretroviral treatment and resistance].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Drug Resistance, Microbial; HIV-1; Humans; Lamivudine; Mutation; Mycobacterium tuberculosis; Retroviridae Infections; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
[Resistance to antiretroviral drugs].
Topics: Antiviral Agents; Drug Resistance; Drug Resistance, Multiple; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nevirapine; Point Mutation; Retroviridae; Retroviridae Infections; Zidovudine | 1997 |
Platelet dysfunction as the cause of spontaneous bleeding in two haemophilic patients taking HIV protease inhibitors.
Topics: Adolescent; Adult; Anti-HIV Agents; Hemophilia A; Hemorrhage; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine | 1998 |
[Antiretroviral treatment in human immunodeficiency virus infection].
Topics: Antiviral Agents; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Ritonavir; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine | 1997 |
Antiretroviral chemotherapy.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1998 |
Toxicity of antiretroviral agents.
Topics: Anti-HIV Agents; Didanosine; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
Prevalence and incidence of resistance to zidovudine and other antiretroviral drugs.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Prevalence; Reverse Transcriptase Inhibitors; Risk Factors; Saquinavir; Stavudine; Time Factors; Zidovudine | 1997 |
Combined treatment with zidovudine, lamivudine, nelfinavir and ganciclovir in an infant with human immunodeficiency virus type 1 infection and cytomegalovirus encephalitis: case report and review of the literature.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cytomegalovirus Infections; Diseases in Twins; Drug Therapy, Combination; Encephalitis, Viral; Female; Ganciclovir; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lamivudine; Nelfinavir; Zidovudine | 1999 |
HIV-associated pityriasis rubra pilaris responsive to triple antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Lamivudine; Pityriasis Rubra Pilaris; Saquinavir; Zidovudine | 1999 |
Antiretrovirals.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine | 1999 |
Review of NNRTIs: 'today and tomorrow'.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; Zidovudine | 1999 |
Coming therapies: abacavir.
Topics: Anti-HIV Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Zidovudine | 1999 |
Finding a role for zalcitabine in the HAART era.
Topics: Anti-HIV Agents; Drug Resistance; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Saquinavir; Zalcitabine; Zidovudine | 1998 |
[Early treatment of sexual exposure to human immunodeficiency virus].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Combinations; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Nelfinavir; Probability; Risk Factors; Sexual Behavior; Sexual Partners; Time Factors; Zidovudine | 2000 |
Stavudine plus a non-thymidine nucleoside reverse transcriptase inhibitor as a backbone for highly active antiretroviral therapy.
Topics: Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1998 |
Transgenic mice as a chemotherapeutic model for hepatitis B virus infection.
Topics: Administration, Oral; Animals; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Genome, Viral; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B Virus, Woodchuck; Humans; Interferon-alpha; Lamivudine; Mice; Mice, Transgenic; Polymerase Chain Reaction; Sex Factors; Time Factors; Viral Load; Virus Replication; Zidovudine | 1998 |
Intracellular studies of the nucleoside reverse transcriptase inhibitor active metabolites: a review.
Topics: Adult; Aged; Anti-HIV Agents; Antimetabolites; Cells, Cultured; Child; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phosphates; Phosphorylation; Polyphosphates; Radioimmunoassay; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine | 2000 |
Mother-to-child HIV-1 transmission: state of the art and implications for public policy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Cesarean Section; Clinical Trials as Topic; Female; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Monitoring, Physiologic; Pregnancy; Pregnancy Complications, Infectious; Public Policy; Registries; Reverse Transcriptase Inhibitors; Risk Factors; RNA, Viral; Viral Load; Zidovudine | 2000 |
Recurrence of the acute HIV syndrome after interruption of antiretroviral therapy in a patient with chronic HIV infection: A case report.
Topics: Acute Disease; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Chronic Disease; Disease Progression; Drug Therapy, Combination; Fever; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Recurrence; Reverse Transcriptase Inhibitors; RNA, Viral; Syndrome; Viral Load; Zidovudine | 2000 |
Occupational exposure to HIV and post-exposure prophylaxis in healthcare workers.
Topics: Anti-HIV Agents; Health Personnel; HIV Infections; HIV Seropositivity; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Exposure; Reverse Transcriptase Inhibitors; United Kingdom; Zidovudine | 2000 |
Management of the infant born to a mother infected with human immunodeficiency virus type 1 (HIV-1): current concepts.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Zidovudine | 2000 |
International perspectives on antiretroviral resistance. Nucleoside reverse transcriptase inhibitor resistance.
Topics: Dideoxynucleosides; Disease Progression; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 2001 |
Anti-retroviral treatment in Nigeria: a review.
Topics: Anti-HIV Agents; Clinical Trials as Topic; HIV Infections; Humans; Lamivudine; Nigeria; Zidovudine | 2000 |
Primary biliary cirrhosis: new thoughts on pathophysiology and treatment.
Topics: Alkaline Phosphatase; Autoimmunity; DNA; Drug Combinations; Humans; Lamivudine; Liver; Liver Cirrhosis, Biliary; Pilot Projects; Retroviridae; Retroviridae Infections; Reverse Transcriptase Inhibitors; Zidovudine | 2002 |
HIV vaccine evaluation center in Rio de Janeiro, Brazil.
Topics: Adolescent; Adult; AIDS Vaccines; Anti-HIV Agents; Behavior Therapy; Bisexuality; Brazil; Clinical Trials, Phase II as Topic; Disease Transmission, Infectious; Enzyme-Linked Immunosorbent Assay; Follow-Up Studies; HIV Antibodies; HIV Envelope Protein gp120; HIV Infections; HIV Seropositivity; Homosexuality; Humans; Incidence; Lamivudine; Male; Middle Aged; Safety; Sensitivity and Specificity; Zidovudine | 2002 |
Trizivir.
Topics: Antiretroviral Therapy, Highly Active; Biological Availability; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; Drug Evaluation; HIV Infections; HIV-1; Humans; Intestinal Absorption; Lamivudine; Zidovudine | 2002 |
[Complete auriculoventricular block in a patient treatment with Lopinavir/Ritonavir].
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Aryl Hydrocarbon Hydroxylases; Bundle-Branch Block; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Inhibitors; Heart; Heart Block; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Oxidoreductases, N-Demethylating; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Syncope; Zidovudine | 2002 |
Antiretroviral therapy-induced psychosis: case report and brief review of the literature.
Topics: Adult; Antipsychotic Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Female; Hallucinations; HIV Seropositivity; Humans; Lamivudine; Nevirapine; Psychoses, Substance-Induced; Zidovudine | 2003 |
Effects of nucleoside-based antiretroviral chemotherapy on human T cell leukaemia/lymphotropic virus type 1 (HTLV-1) infection in vitro.
Topics: Animals; Anti-Retroviral Agents; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Lamivudine; Nucleosides; Zidovudine | 2003 |
Lamivudine/zidovudine/abacavir: triple combination tablet.
Topics: Administration, Oral; Anti-HIV Agents; Biological Availability; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine | 2003 |
Where now for Trizivir? Role of the triple-NRTI pill post-ACTG 5095.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Chemistry, Pharmaceutical; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Humans; Lamivudine; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine | 2003 |
The continuing evolution of HIV therapy.
Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2003 |
Evolution of HIV-1-related conjunctival molluscum contagiosum under HAART: report of a bilaterally manifesting case and literature review.
Topics: Adult; Antiretroviral Therapy, Highly Active; Conjunctival Diseases; Drug Combinations; Eye Infections, Viral; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Molluscum Contagiosum; Zidovudine | 2004 |
Prognostic factors in lactic acidosis syndrome caused by nucleoside reverse transcriptase inhibitors: report of eight cases and review of the literature.
Topics: Acidosis, Lactic; Adult; Didanosine; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; New York; Reverse Transcriptase Inhibitors; Stavudine; Syndrome; Zidovudine | 2004 |
Antiretroviral therapy during pregnancy and early neonatal life: consequences for HIV-exposed, uninfected children.
Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Zidovudine | 2004 |
Nucleoside reverse transcriptase inhibitors, mitochondrial DNA and AIDS therapy.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; DNA Replication; DNA, Mitochondrial; Humans; Lamivudine; Mitochondria; Nucleosides; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2005 |
Piloting post-exposure prophylaxis in Kenya raises specific concerns for the management of childhood rape.
Topics: Adolescent; Adult; Anti-HIV Agents; Body Weight; Child; Child Abuse, Sexual; Child, Preschool; Feasibility Studies; Female; HIV Infections; Humans; Infant; Kenya; Lamivudine; Male; Pilot Projects; Practice Guidelines as Topic; Rape; Risk Factors; Rural Health; Sexually Transmitted Diseases; Zidovudine | 2006 |
Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa?
Topics: Adult; Anti-HIV Agents; Breast Feeding; Drug Combinations; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Perinatal Care; Randomized Controlled Trials as Topic; Regression Analysis; Risk Factors; Treatment Outcome; Zidovudine | 2005 |
[The treatment of HIV infection].
Topics: Adenine; Anti-Retroviral Agents; Carbamates; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Sulfonamides; Tenofovir; Zidovudine | 2005 |
Triple-nucleoside analog antiretroviral therapy: is there still a role in clinical practice? A review.
Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prognosis; Treatment Outcome; Zidovudine | 2005 |
Evidence behind the WHO guidelines: hospital care for children: what antiretroviral agents and regimens are effective in the prevention of mother-to-child transmission of HIV?
Topics: Anti-HIV Agents; Breast Feeding; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; World Health Organization; Zidovudine | 2006 |
Evolving simplified treatment strategies for HIV infection: the role of a single-class quadruple-nucleoside/nucleotide regimen of trizivir and tenofovir.
Topics: Adenine; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2006 |
Computational models of antiviral toxicity.
Topics: Anti-HIV Agents; Computer Simulation; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Molecular Structure; Stavudine; Zidovudine | 2007 |
Abacavir sulfate/lamivudine/zidovudine fixed combination in the treatment of HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Treatment Outcome; Zidovudine | 2007 |
Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection.
Topics: Anti-HIV Agents; Antimetabolites; Antiretroviral Therapy, Highly Active; Child; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Outcome; Zidovudine | 2007 |
Quadruple nucleoside therapy with zidovudine, lamivudine, abacavir and tenofovir in the treatment of HIV.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine | 2007 |
[Adipose tissue hypertrophy after Lipostructure in HIV patient with antiretroviral treatment. Case report and literature review].
Topics: Adipose Tissue; Adult; Anti-Retroviral Agents; Drug Combinations; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Hypertrophy; Lamivudine; Male; Postoperative Complications; Zidovudine | 2009 |
Non-occupational postexposure prophylaxis for HIV: a systematic review.
Topics: Anti-HIV Agents; Cost-Benefit Analysis; Databases, Bibliographic; Drug Combinations; Drug Therapy, Combination; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Lopinavir; Premedication; Pyrimidinones; Ritonavir; Substance Abuse, Intravenous; Time Factors; Treatment Outcome; Unsafe Sex; Zidovudine | 2009 |
[The "induction-maintenance" strategy].
Topics: Adipose Tissue; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Viral Load; Virus Replication; Zidovudine | 2008 |
A combination drug of abacavir-lamivudine-zidovudine (Trizivir) for treating HIV infection and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Drug Combinations; HIV Infections; Humans; Lamivudine; Nelfinavir; Oligopeptides; Pyridines; Randomized Controlled Trials as Topic; Zidovudine | 2009 |
Tenofovir or zidovudine in three-drug combination therapy with one nucleoside reverse transcriptase inhibitor and one non-nucleoside reverse transcriptase inhibitor for initial treatment of HIV infection in antiretroviral-naïve individuals.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2010 |
Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection.
Topics: Anti-HIV Agents; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Zidovudine | 2011 |
HIV-1-resistance-associated mutations after failure of first-line antiretroviral treatment among children in resource-poor regions: a systematic review.
Topics: Adolescent; Africa; Alkynes; Anti-HIV Agents; Asia; Benzoxazines; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Developing Countries; Drug Resistance, Viral; Female; Health Resources; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Latin America; Lopinavir; Male; Mutation; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Treatment Failure; Viral Load; Zidovudine | 2011 |
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).
Topics: Adenine; Adult; Amniotic Fluid; Anti-HIV Agents; Cyclohexanes; Enfuvirtide; Female; Fetal Blood; Fetus; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Maraviroc; Nevirapine; Organophosphonates; Peptide Fragments; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Viral Load; Zidovudine | 2011 |
Antiretrovirals for HIV Exposure Prophylaxis.
Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine | 2012 |
Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Nelfinavir; Oligopeptides; Pyridines; Randomized Controlled Trials as Topic; Zidovudine | 2013 |
A randomized pahse I bioequivalence clinincal trial of a paediatric fixed-dose combination antiretroviral reconstitutable suspension in healthy adult volunteers.
Topics: Adult; Anti-HIV Agents; Cross-Over Studies; Drug Combinations; Female; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Therapeutic Equivalency; Young Adult; Zidovudine | 2013 |
Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV.
Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lipids; Maintenance Chemotherapy; Middle Aged; Nevirapine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load; Young Adult; Zidovudine | 2013 |
Choice of antiretroviral drugs for postexposure prophylaxis for children: a systematic review.
Topics: Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Nevirapine; Post-Exposure Prophylaxis; Pregnancy; Prospective Studies; Randomized Controlled Trials as Topic; Ritonavir; Zidovudine | 2015 |
Combination antiretroviral studies for patients with primary biliary cirrhosis.
Topics: Animals; Anti-Retroviral Agents; Betaretrovirus; Clinical Trials as Topic; Drug Therapy, Combination; Emtricitabine; Humans; Lamivudine; Liver Cirrhosis, Biliary; Lopinavir; Mammary Tumor Virus, Mouse; Mice; Tenofovir; Zidovudine | 2016 |
Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis.
Topics: Adult; Anti-Retroviral Agents; Drug Combinations; Emtricitabine; Female; Hepatitis B; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Ritonavir; Tenofovir; Young Adult; Zidovudine | 2017 |
Zidovudine/Lamivudine vs. Abacavir/Lamivudine vs. Tenofovir/Emtricitabine in fixed-dose combinations as initial treatment for HIV patients: a systematic review and network meta-analysis.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Lamivudine; Network Meta-Analysis; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine | 2017 |
Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs.
Topics: Abnormalities, Drug-Induced; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Congenital Abnormalities; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Network Meta-Analysis; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Stavudine; Stillbirth; Zidovudine | 2018 |
Regression of human immunodeficiency virus-associated oral Kaposi sarcoma with combined antiretroviral therapy: A case report and literature review.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Combinations; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Mouth Neoplasms; Ritonavir; Sarcoma, Kaposi; Zidovudine | 2019 |
Acquired HIV drug resistance mutations on first-line antiretroviral therapy in Southern Africa: Systematic review and Bayesian evidence synthesis.
Topics: Adult; Anti-Retroviral Agents; Bayes Theorem; Drug Resistance, Viral; Emtricitabine; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Tenofovir; Viral Load; Zidovudine | 2022 |
Factors associated with viral suppression and rebound among adult HIV patients on treatment: a retrospective study in Ghana.
Topics: Adult; Anti-HIV Agents; Ghana; HIV Infections; Humans; Lamivudine; Nevirapine; Retrospective Studies; Viral Load; Zidovudine | 2022 |
Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus.
Topics: Antiviral Agents; Coinfection; DNA, Viral; Emtricitabine; Female; Hepatitis B e Antigens; Hepatitis B virus; HIV; HIV Infections; HIV Seropositivity; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnant Women; Ritonavir; Tenofovir; Zidovudine | 2023 |
399 trial(s) available for lamivudine and zidovudine
Article | Year |
---|---|
Intracellular pharmacokinetics of once versus twice daily zidovudine and lamivudine in adolescents.
Topics: Adolescent; Adult; Anti-HIV Agents; Area Under Curve; CD4 Lymphocyte Count; Child; Cross-Over Studies; Drug Combinations; Female; Half-Life; Humans; Lamivudine; Male; Monocytes; Phosphorylation; Zidovudine | 2007 |
Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. North American HIV Working Party.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zalcitabine; Zidovudine | 1995 |
Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy.
Topics: Antiviral Agents; Base Sequence; CD4 Lymphocyte Count; Cell Line; Codon; Drug Resistance, Microbial; Drug Therapy, Combination; HeLa Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Serial Passage; Zalcitabine; Zidovudine | 1995 |
Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (--)-2',3'-dideoxy-3'-thiacytidine.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Resistance, Microbial; Genotype; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phenotype; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1995 |
Zidovudine and lamivudine: results of phase III studies.
Topics: Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine | 1995 |
Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine | 1996 |
Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine | 1996 |
Lamivudine plus zidovudine compared with zalcitabine plus zidovudine in patients with HIV infection. A randomized, double-blind, placebo-controlled trial. North American HIV Working Party.
Topics: Adult; Antiviral Agents; beta 2-Microglobulin; Biopterins; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Core Protein p24; HIV Infections; Humans; Lamivudine; Male; Neopterin; Polymerase Chain Reaction; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Outcome; Zalcitabine; Zidovudine | 1996 |
Virological and immunological analysis of a triple combination pilot study with loviride, lamivudine and zidovudine in HIV-1-infected patients.
Topics: Acetamides; Acetophenones; Adult; Antiviral Agents; Case-Control Studies; CD4 Lymphocyte Count; Cross-Over Studies; DNA Mutational Analysis; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; Pilot Projects; RNA, Viral; Zalcitabine; Zidovudine | 1996 |
HIV-1 RNA levels and the development of clinical disease. North American Lamivudine HIV Working Group.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Predictive Value of Tests; Proportional Hazards Models; RNA, Viral; Zidovudine | 1996 |
Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients.
Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Genes, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Virus Replication; Zidovudine | 1996 |
CD8+ lymphocyte responses to antiretroviral therapy of HIV infection.
Topics: Acetamides; Acetophenones; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Lamivudine; Lymphocyte Count; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zalcitabine; Zidovudine | 1996 |
Efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine (ddC) plus lamivudine (3TC) versus double (ZDV+3TC) combination therapy in patients previously treated with ZDV+ddC.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Viral Load; Zalcitabine; Zidovudine | 1996 |
The treatment of antiretroviral-naive subjects with the 3TC/zidovudine combination: a review of North American (NUCA 3001) and European (NUCB 3001) trials.
Topics: Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Europe; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; North America; Viral Load; Zidovudine | 1996 |
Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments: a meta-analysis of controlled trials.
Topics: Adolescent; Adult; Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Disease Progression; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; United States; Zidovudine | 1997 |
Effects of a combination of zidovudine, didanosine, and lamivudine on primary human immunodeficiency virus type 1 infection.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4-CD8 Ratio; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocytes; Male; Pilot Projects; Proviruses; RNA, Viral; Zidovudine | 1997 |
Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Dendritic Cells; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Image Processing, Computer-Assisted; In Situ Hybridization; Kinetics; Lamivudine; Leukocytes, Mononuclear; Macrophages; Palatine Tonsil; Proviruses; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Viral Load; Virus Replication; Zidovudine | 1997 |
Randomised trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: the CAESAR trial.
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Health Services; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1997 |
Cytomegalovirus retinitis after initiation of highly active antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Saquinavir; Zidovudine | 1997 |
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine | 1997 |
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; RNA, Viral; Viral Load; Zidovudine | 1997 |
Stavudine, lamivudine and indinavir in children with advanced HIV-1 infection: preliminary experience.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pilot Projects; Retrospective Studies; Stavudine; Zidovudine | 1997 |
Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure.
Topics: Anti-HIV Agents; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymph Nodes; RNA, Viral; Viral Load; Zidovudine | 1997 |
Quantification of HIV-1 proviral DNA by a standardized colorimetric PCR-based assay.
Topics: Adult; Anti-HIV Agents; Colorimetry; Didanosine; DNA, Viral; Evaluation Studies as Topic; Female; HIV-1; Humans; Indinavir; Lamivudine; Male; Polymerase Chain Reaction; Proviruses; Ritonavir; RNA, Viral; Transcription, Genetic; Zalcitabine; Zidovudine | 1998 |
Decrease of HIV-1 RNA levels in lymphoid tissue and peripheral blood during treatment with ritonavir, lamivudine and zidovudine. Ritonavir/3TC/ZDV Study Group.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphoid Tissue; Male; Palatine Tonsil; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 1998 |
Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy.
Topics: Amino Acid Sequence; Base Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Lymph Nodes; Molecular Sequence Data; Mutation; RNA, Viral; Viral Load; Virus Replication; Zidovudine | 1998 |
Antiviral effect of double and triple drug combinations amongst HIV-infected adults: lessons from the implementation of viral load-driven antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Cohort Studies; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Multivariate Analysis; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1998 |
The effects of lamivudine treatment on HIV-1 disease progression are highly correlated with plasma HIV-1 RNA and CD4 cell count.
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; RNA, Viral; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine | 1998 |
Pilot study of zidovudine-lamivudine combination therapy in vertically HIV-infected antiretroviral-naive children.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pilot Projects; RNA, Viral; Viral Load; Zidovudine | 1998 |
Impact of zidovudine plus lamivudine or zalcitabine on health-related quality of life.
Topics: Adult; Anti-Bacterial Agents; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Quality of Life; Treatment Outcome; Zalcitabine; Zidovudine | 1998 |
A phase I/II study of the protease inhibitor indinavir in children with HIV infection.
Topics: Adolescent; Adult; Biological Availability; Capsules; CD4 Lymphocyte Count; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infant; Lamivudine; Male; Suspensions; Viral Load; Virus Replication; Zidovudine | 1998 |
Evolution of cytotoxic T lymphocyte responses to human immunodeficiency virus type 1 in patients with symptomatic primary infection receiving antiretroviral triple therapy.
Topics: Anti-HIV Agents; Cell Line, Transformed; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; T-Lymphocytes, Cytotoxic; Viral Load; Zidovudine | 1998 |
Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315.
Topics: Adult; Anti-HIV Agents; Antigens; B-Lymphocytes; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Antigens; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hypersensitivity, Delayed; Lamivudine; Lymphocyte Activation; Lymphocyte Count; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; T-Lymphocyte Subsets; Time Factors; Zidovudine | 1998 |
Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Viral Load; Zidovudine | 1998 |
Rate of HIV-1 decline following antiretroviral therapy is related to viral load at baseline and drug regimen.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Models, Theoretical; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 1998 |
An open randomized controlled trial of zidovudine plus lamivudine versus stavudine plus lamivudine.
Topics: Adult; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Homosexuality, Male; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1998 |
Treatment response and durability of a double protease inhibitor therapy with saquinavir and ritonavir in an observational cohort of HIV-1-infected individuals.
Topics: Adult; Anti-HIV Agents; CD4-CD8 Ratio; Cohort Studies; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Observation; Risk Factors; Ritonavir; Saquinavir; Treatment Failure; Viral Load; Zidovudine | 1998 |
Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring.
Topics: Administration, Oral; Adolescent; Adult; Amniotic Fluid; Anti-HIV Agents; Black People; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Pregnancy; Random Allocation; RNA, Viral; South Africa; Viral Load; Zidovudine | 1998 |
Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-HIV Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Humans; Lamivudine; Male; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifabutin; Stavudine; Zidovudine | 1998 |
A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team.
Topics: Adolescent; Anti-HIV Agents; CD4 Antigens; Child; Child, Preschool; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Neurodegenerative Diseases; Polymerase Chain Reaction; RNA, Viral; Survival Rate; Zidovudine | 1998 |
Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy. AIDS Clinical Trials Group Study 343 Team.
Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Multivariate Analysis; Remission Induction; RNA, Viral; Treatment Failure; Viral Load; Zidovudine | 1998 |
A randomized trial of three maintenance regimens given after three months of induction therapy with zidovudine, lamivudine, and indinavir in previously untreated HIV-1-infected patients. Trilège (Agence Nationale de Recherches sur le SIDA 072) Study Team.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Remission Induction; RNA, Viral; Treatment Failure; Viral Load; Zidovudine | 1998 |
A randomized double-blind trial of the addition of lamivudine or matching placebo to current nucleoside analogue reverse transcriptase inhibitor therapy in HIV-infected children: the PENTA-4 trial. Paediatric European Network for Treatment of AIDS.
Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine | 1998 |
A dose-ranging study to evaluate the safety and efficacy of abacavir alone or in combination with zidovudine and lamivudine in antiretroviral treatment-naive subjects.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; HIV-1; Humans; Lamivudine; RNA, Viral; Time Factors; Viral Load; Zidovudine | 1998 |
Highly active antiretroviral therapy results in a decrease in CD8+ T cell activation and preferential reconstitution of the peripheral CD4+ T cell population with memory rather than naive cells.
Topics: Anti-HIV Agents; Antigens, CD; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Flow Cytometry; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Immunophenotyping; Indinavir; Lamivudine; Lymphocyte Activation; Statistics, Nonparametric; T-Lymphocyte Subsets; Viral Load; Zidovudine | 1998 |
Human immunodeficiency virus type 1 expressing the lamivudine-associated M184V mutation in reverse transcriptase shows increased susceptibility to adefovir and decreased replication capability in vitro.
Topics: Adenine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Lamivudine; Organophosphonates; Point Mutation; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine | 1999 |
Randomized, controlled phase II trial of subcutaneous interleukin-2 in combination with highly active antiretroviral therapy (HAART) in HIV patients.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Injections, Subcutaneous; Interleukin-2; Lamivudine; Male; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; Saquinavir; Viral Load; Zidovudine | 1998 |
Prolonged suppression of human immunodeficiency virus type 1 (HIV-1) viremia in persons with advanced disease results in enhancement of CD4 T cell reactivity to microbial antigens but not to HIV-1 antigens.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antigens, Bacterial; CD4-Positive T-Lymphocytes; Cell Division; Chemokines; Cytokines; Double-Blind Method; Female; HIV Antigens; HIV-1; Humans; Indinavir; Lamivudine; Male; Mitogens; RNA, Viral; Viremia; Zidovudine | 1999 |
The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV-1; Homosexuality, Male; Humans; Lamivudine; Male; Middle Aged; Pilot Projects; Ritonavir; RNA, Viral; T-Lymphocytes, Cytotoxic; Time Factors; Viremia; Virus Replication; Zidovudine | 1999 |
Initial multicenter experience with double nucleoside therapy for human immunodeficiency virus infection during pregnancy.
Topics: Adult; Anti-HIV Agents; Canada; Confidence Intervals; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prospective Studies; Statistics, Nonparametric; Treatment Outcome; United States; Zidovudine | 1998 |
[Increased serum level of naive CD8+-T-cells during intensive antiretroviral therapy].
Topics: Antiviral Agents; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Lymphocyte Count; Male; Saquinavir; Zidovudine | 1998 |
Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection. AIDS Clinical Trials Group 347 Study Team.
Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Furans; HIV Infections; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Sulfonamides; Zidovudine | 1999 |
Clinical cross-resistance between the HIV-1 protease inhibitors saquinavir and indinavir and correlations with genotypic mutations.
Topics: CD4 Lymphocyte Count; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Viral Load; Zidovudine | 1999 |
[Experiences with antiretroviral combination therapy].
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; N-Glycosyl Hydrolases; Retrospective Studies; Ritonavir; RNA, Viral; Zidovudine | 1999 |
Cerebrospinal-fluid HIV-1 RNA and drug concentrations after treatment with lamivudine plus zidovudine or stavudine.
Topics: Adult; AIDS Dementia Complex; Analysis of Variance; Anti-HIV Agents; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Drug Combinations; Follow-Up Studies; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; RNA, Viral; Spinal Puncture; Stavudine; Zidovudine | 1998 |
Lamivudine/zidovudine as a combined formulation tablet: bioequivalence compared with lamivudine and zidovudine administered concurrently and the effect of food on absorption.
Topics: Absorption; Adolescent; Adult; Anti-HIV Agents; Area Under Curve; Cross-Over Studies; Eating; Fasting; Female; Food-Drug Interactions; Headache; Humans; Lamivudine; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Tablets; Therapeutic Equivalency; Zidovudine | 1999 |
Randomized trial comparing saquinavir soft gelatin capsules versus indinavir as part of triple therapy (CHEESE study).
Topics: Adult; Anti-HIV Agents; Capsules; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Gelatin; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Treatment Outcome; Zidovudine | 1999 |
Single-dose pharmacokinetics and safety of abacavir (1592U89), zidovudine, and lamivudine administered alone and in combination in adults with human immunodeficiency virus infection.
Topics: Adolescent; Adult; Anti-HIV Agents; Cross-Over Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Zidovudine | 1999 |
Safety and efficacy of ritonavir and saquinavir in combination with zidovudine and lamivudine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Genotype; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Mutation; Pilot Projects; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Severity of Illness Index; Time Factors; Viral Load; Zidovudine | 1999 |
Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cohort Studies; DNA, Viral; Drug Therapy, Combination; HIV Antibodies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Prospective Studies; RNA, Viral; T-Lymphocyte Subsets; Viremia; Zidovudine | 1999 |
The ALBI trial: a randomized controlled trial comparing stavudine plus didanosine with zidovudine plus lamivudine and a regimen alternating both combinations in previously untreated patients infected with human immunodeficiency virus.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viremia; Zidovudine | 1999 |
HIV-1 rebound during interruption of highly active antiretroviral therapy has no deleterious effect on reinitiated treatment. Comet Study Group.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 1999 |
Lamivudine in combination with zidovudine, stavudine, or didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group Protocol 306 Invest
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine | 1999 |
HIV infection perturbs DNA content of lymphoid cells: partial correction after 'suppression' of virus replication.
Topics: Anti-HIV Agents; Apoptosis; Cell Cycle; Cross-Sectional Studies; DNA; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Ritonavir; RNA, Viral; Viral Load; Virus Replication; Zidovudine | 1999 |
A randomized, controlled trial of indinavir, zidovudine, and lamivudine in adults with advanced human immunodeficiency virus type 1 infection and prior antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Survival Rate; Zidovudine | 1999 |
Cerebrospinal fluid human immunodeficiency virus type 1 (HIV-1) suppression and efavirenz drug concentrations in HIV-1-infected patients receiving combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Viral Load; Zidovudine | 1999 |
Immune reconstitution after 2 years of successful potent antiretroviral therapy in previously untreated human immunodeficiency virus type 1-infected adults.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Follow-Up Studies; HIV-1; Humans; Immunologic Memory; Lamivudine; Lymphocyte Count; Lymphocytes; Reference Values; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; T-Lymphocytes; Time Factors; Viral Load; Zidovudine | 1999 |
Highly active antiretroviral treatment initiated early in the course of symptomatic primary HIV-1 infection: results of the ANRS 053 trial.
Topics: Anti-HIV Agents; Confidence Intervals; Drug Therapy, Combination; Female; France; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Male; Ritonavir; RNA, Viral; Viral Load; Zidovudine | 1999 |
Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients.
Topics: Adult; Anti-HIV Agents; Cytokines; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hypersensitivity, Delayed; Interleukin-2; Lamivudine; Lymphocyte Activation; Male; T-Lymphocytes; Thalidomide; Viral Load; Zidovudine | 1999 |
Long-term effects of antiretroviral combination therapy on HIV type 1 DNA levels.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Data Interpretation, Statistical; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Polymerase Chain Reaction; RNA, Viral; Stavudine; Time Factors; Zidovudine | 1999 |
Cell-associated HIV-1 messenger RNA and DNA in T-helper cell and monocytes in asymptomatic HIV-1-infected subjects on HAART plus an inactivated HIV-1 immunogen.
Topics: AIDS Vaccines; Anti-HIV Agents; CD4 Lymphocyte Count; Combined Modality Therapy; DNA, Viral; Drug Therapy, Combination; Freund's Adjuvant; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Monocytes; Pilot Projects; RNA, Viral; T-Lymphocytes, Helper-Inducer; Viral Load; Zidovudine | 1999 |
Preliminary experiences with triple therapy including nelfinavir and two reverse transcriptase inhibitors in previously untreated HIV-infected children.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nelfinavir; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 1999 |
Evidence of stavudine-related phenotypic resistance among zidovudine-pretreated HIV-1-infected subjects receiving a therapeutic regimen of stavudine plus lamivudine.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Phenotype; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine | 1999 |
Lamivudine reduces healthcare resource use when added to zidovudine-containing regimens in patients with HIV infection.
Topics: Adult; Ambulatory Care; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Length of Stay; Male; Zidovudine | 1999 |
A prospective cost-consequence analysis of adding lamivudine to zidovudine-containing antiretroviral treatment regimens for HIV infection in the US.
Topics: Adult; Ambulatory Care; Anti-HIV Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Female; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Length of Stay; Male; Middle Aged; Prospective Studies; United States; Zidovudine | 1999 |
A prospective evaluation of the cost effectiveness of adding lamivudine to zidovudine-containing antiretroviral treatment regimens in HIV infection. European perspective.
Topics: Adult; Ambulatory Care; Anti-HIV Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Europe; Female; Health Care Costs; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Male; Prospective Studies; Zidovudine | 1999 |
An evaluation of the cost effectiveness of adding lamivudine to zidovudine-containing regimens in HIV infection. Canadian perspective.
Topics: Adult; Ambulatory Care; Anti-HIV Agents; Canada; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Female; Health Care Costs; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Male; Prospective Studies; Zidovudine | 1999 |
Quality of life and treatment satisfaction after the addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens in treatment-experienced patients with HIV infection.
Topics: Acetamides; Acetophenones; Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Patient Satisfaction; Quality of Life; Zidovudine | 1999 |
A randomized study comparing triple versus double antiretroviral therapy or no treatment in HIV-1-infected patients in very early stage disease: the Spanish Earth-1 study.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Palatine Tonsil; Ritonavir; RNA, Viral; Spain; Stavudine; Viremia; Zalcitabine; Zidovudine | 1999 |
A phase II safety and efficacy study of amprenavir in combination with zidovudine and lamivudine in HIV-infected patients with limited antiretroviral experience. Amprenavir PROAB2002 Study Team.
Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Female; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nausea; RNA, Viral; Safety; Sulfonamides; Time Factors; Viremia; Zidovudine | 1999 |
Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team.
Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 1999 |
Alteration of complement protein levels after antiretroviral therapy in HIV-infected persons.
Topics: Anti-HIV Agents; Complement Pathway, Classical; Complement System Proteins; Drug Administration Schedule; Drug Therapy, Combination; HIV Antibodies; HIV Antigens; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine | 1999 |
T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART).
Topics: Anti-HIV Agents; Antigens, CD; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; HIV Seronegativity; HIV-1; Humans; Indinavir; Ki-67 Antigen; Lamivudine; Longitudinal Studies; Lymphocyte Activation; RNA, Viral; Saquinavir; T-Lymphocyte Subsets; T-Lymphocytes; Viral Load; Zidovudine | 2000 |
Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic response.
Topics: Anti-HIV Agents; Candida; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; Humans; Hypersensitivity, Delayed; Immune System; Lamivudine; Mumps virus; Ritonavir; RNA, Viral; Zidovudine | 2000 |
Update on study 006--EFV + AZT + 3TC versus the current 'standard of care' IDV + AZT + 3TC.
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Humans; Indinavir; Lamivudine; Lipid Metabolism; Oxazines; Viral Load; Zidovudine | 1999 |
Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype.
Topics: Amino Acid Substitution; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Zidovudine | 1999 |
Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Trilège (Agence Nationale de Recherches sur le SIDA 072) Study Team).
Topics: Anti-HIV Agents; Case-Control Studies; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Patient Compliance; Treatment Failure; Viral Load; Zidovudine | 2000 |
Cerebrospinal fluid beta2-microglobulin, monocyte chemotactic protein-1, and soluble tumour necrosis factor alpha receptors before and after treatment with lamivudine plus zidovudine or stavudine.
Topics: Adult; Anti-HIV Agents; beta 2-Microglobulin; Chemokine CCL2; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; Receptors, Tumor Necrosis Factor; Solubility; Stavudine; Zidovudine | 2000 |
Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: a randomized controlled trial. Pediatric AIDS Clinical Trials Group 338 Study Team.
Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2000 |
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine-lamivudine-ritonavir: genotypic analysis of human immunodeficiency virus type 1 isolates from AIDS clinical trials group protocol 315.ACTG Protocol 315 Team.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Viral Load; Zidovudine | 2000 |
RANTES production by T cells and CD8-mediated inhibition of human immunodeficiency virus gene expression before initiation of potent antiretroviral therapy predict sustained suppression of viral replication.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Chemokine CCL5; Gene Expression; HIV Infections; HIV Long Terminal Repeat; HIV-1; Humans; Lamivudine; Predictive Value of Tests; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Single-Blind Method; T-Lymphocytes; Viral Load; Virus Replication; Zidovudine | 2000 |
Human immunodeficiency virus-infected persons with mutations conferring resistance to zidovudine show reduced virologic responses to hydroxyurea and stavudine-lamivudine.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hydroxyurea; Lamivudine; Logistic Models; Mutation; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 2000 |
Prediction of HIV-1 RNA suppression and its durability during treatment with zidovudine/lamivudine.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV-1; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; RNA, Viral; Zidovudine | 1998 |
Zidovudine resensitization and dual HIV-1 resistance to zidovudine and lamivudine in the delta lamivudine roll-over study.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Resistance; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Phenotype; RNA, Viral; Zidovudine | 1999 |
AVANTI 1: randomized, double-blind trial to evaluate the efficacy and safety of zidovudine plus lamivudine versus zidovudine plus lamivudine plus loviride in HIV-infected antiretroviral-naive patients. AVANTI Study Group.
Topics: Acetamides; Acetophenones; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Zidovudine | 1999 |
Effects of early antiretroviral treatment on HIV-1 RNA in blood and lymphoid tissue: a randomized trial of double versus triple therapy. Swiss HIV Cohort Study.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphoid Tissue; Male; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Time Factors; Viral Load; Zidovudine | 2000 |
HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy.
Topics: Cohort Studies; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2000 |
Response to immunization with recall and neoantigens after prolonged administration of an HIV-1 protease inhibitor-containing regimen. ACTG 375 team. AIDS Clinical Trials Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination; Female; Hemocyanins; Hepatitis A Vaccines; HIV-1; Humans; Hypersensitivity, Delayed; Injections, Intradermal; Lamivudine; Male; Middle Aged; Ritonavir; T-Lymphocytes; Tetanus Toxoid; Thymus Gland; Vaccination; Viral Hepatitis Vaccines; Zidovudine | 2000 |
AVANTI 2. Randomized, double-blind trial to evaluate the efficacy and safety of zidovudine plus lamivudine versus zidovudine plus lamivudine plus indinavir in HIV-infected antiretroviral-naive patients.
Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Patient Compliance; Placebos; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2000 |
The effects of protease inhibitor therapy on human immunodeficiency virus type 1 levels in semen (AIDS clinical trials group protocol 850).
Topics: Adult; Carbamates; Double-Blind Method; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Regression Analysis; RNA, Viral; Semen; Sulfonamides; Virus Shedding; Zidovudine | 2000 |
Efficacy, safety, and adherence with a twice-daily combination lamivudine/zidovudine tablet formulation, plus a protease inhibitor, in HIV infection.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Patient Compliance; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2000 |
A randomized, controlled, phase II trial comparing escalating doses of subcutaneous interleukin-2 plus antiretrovirals versus antiretrovirals alone in human immunodeficiency virus-infected patients with CD4+ cell counts >/=350/mm3.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Injections, Subcutaneous; Interleukin-2; Lamivudine; Lymphocyte Count; Male; Nelfinavir; Nevirapine; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 2000 |
Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease.
Topics: Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cytokines; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load; Virus Replication; Zidovudine | 2000 |
Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy.
Topics: Adult; Alleles; Anti-HIV Agents; Chemokine CXCL12; Chemokines, CXC; Drug Therapy, Combination; Female; Gene Frequency; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Linkage Disequilibrium; Male; Polymorphism, Genetic; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, Cytokine; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine | 2000 |
Dual nucleoside regimens in nonadvanced HIV infection: prospective follow-up of 130 patients, Aquitaine Cohort, 1996 to 1998. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine (GECSA).
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Multivariate Analysis; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Zalcitabine; Zidovudine | 2000 |
Clinical and virologic response to combination treatment with indinavir, zidovudine, and lamivudine in children with human immunodeficiency virus-1 infection: a multicenter study in the Netherlands. On behalf of the Dutch Study Group for Children with HIV
Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Netherlands; Prospective Studies; Zidovudine | 2000 |
Improved prognosis in patients with acquired immunodeficiency syndrome-related lymphoma.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease-Free Survival; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lymphoma, AIDS-Related; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Rate; Vincristine; Zidovudine | 1999 |
Effect of two different combinations of antiretrovirals (AZT+ddI and AZT+3TC) on cytokine production and apoptosis in asymptomatic HIV infection.
Topics: Anti-HIV Agents; Apoptosis; CD4 Lymphocyte Count; CD4-CD8 Ratio; Cytokines; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Prospective Studies; Reverse Transcriptase Inhibitors; Th1 Cells; Viremia; Zidovudine | 2000 |
3-year suppression of HIV viremia with indinavir, zidovudine, and lamivudine.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Genotype; HIV; HIV Infections; Humans; Indinavir; Kidney Calculi; Lamivudine; Male; Middle Aged; RNA, Viral; Viral Load; Viremia; Zidovudine | 2000 |
A randomised, open-label comparison of three highly active antiretroviral therapy regimens including two nucleoside analogues and indinavir for previously untreated HIV-1 infection: the OzCombo1 study.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Stavudine; Viral Load; Zidovudine | 2000 |
Absence of zidovudine resistance in antiretroviral-naive patients following zidovudine/lamivudine/protease inhibitor combination therapy: virological evaluation of the AVANTI 2 and AVANTI 3 studies.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Microbial; Female; Genotype; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; RNA, Viral; Viral Load; Zidovudine | 2000 |
Recovery of replication-competent virus from CD4 T cell reservoirs and change in coreceptor use in human immunodeficiency virus type 1-infected children responding to highly active antiretroviral therapy.
Topics: Adolescent; CD4-Positive T-Lymphocytes; Cell Differentiation; Child; Coculture Techniques; Female; HIV Infections; HIV-1; Humans; Immunophenotyping; Infant; Lamivudine; Leukocytes, Mononuclear; Male; Nelfinavir; Prospective Studies; Receptors, CCR5; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Virus Replication; Zidovudine | 2000 |
Virological and immunological effects of combination antiretroviral therapy with zidovudine, lamivudine, and indinavir during primary human immunodeficiency virus type 1 infection.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Patient Compliance; Zidovudine | 2000 |
Positive influence of the Delta32CCR5 allele on response to highly active antiretroviral therapy (HAART) in HIV-1 infected patients.
Topics: Acquired Immunodeficiency Syndrome; Alleles; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Resistance, Microbial; Female; HIV-1; Humans; Lamivudine; Male; Receptors, CCR5; Zidovudine | 2000 |
Comparison of a point mutation assay with a line probe assay for the detection of the major mutations in the HIV-1 reverse transcriptase gene associated with reduced susceptibility to nucleoside analogues.
Topics: Acetamides; Acetophenones; Anti-HIV Agents; Codon; DNA; DNA Mutational Analysis; Drug Resistance, Microbial; Drug Therapy, Combination; Evaluation Studies as Topic; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 2000 |
Continued lamivudine versus delavirdine in combination with indinavir and zidovudine or stavudine in lamivudine-experienced patients: results of Adult AIDS Clinical Trials Group protocol 370.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Delavirdine; Female; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Viral Load; Zidovudine | 2000 |
A comparison of stavudine plus lamivudine versus zidovudine plus lamivudine in combination with indinavir in antiretroviral naive individuals with HIV infection: selection of thymidine analog regimen therapy (START I).
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thymidine; Zidovudine | 2000 |
A comparison of stavudine, didanosine and indinavir with zidovudine, lamivudine and indinavir for the initial treatment of HIV-1 infected individuals: selection of thymidine analog regimen therapy (START II).
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Viral Load; Zidovudine | 2000 |
Comparative studies of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Administration Schedule; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2000 |
Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zalcitabine; Zidovudine | 2000 |
Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine | 2000 |
Comparison of immunologic restoration and virologic response in plasma, tonsillar tissue, and cerebrospinal fluid in HIV-1-infected patients treated with double versus triple antiretroviral therapy in very early stages: The Spanish EARTH-2 Study. Early An
Topics: Adult; Blood; CD4 Lymphocyte Count; Cell Count; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Palatine Tonsil; Point Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Stavudine; Time Factors; Viral Load; Zidovudine | 2000 |
HAART tolerability: post-exposure prophylaxis in healthcare workers versus treatment in HIV-infected patients.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chemoprevention; Female; Health Personnel; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
Amprenavir in combination with lamivudine and zidovudine versus lamivudine and zidovudine alone in HIV-1-infected antiretroviral-naive adults. Amprenavir PROAB3001 International Study Team.
Topics: Adolescent; Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Furans; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Sulfonamides; Zidovudine | 2000 |
Altered viral fitness of HIV-1 following failure of protease inhibitor-based therapy.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antigens, Viral; Base Sequence; CD4-Positive T-Lymphocytes; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Mice; Mice, SCID; Molecular Sequence Data; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Sequence Analysis, DNA; Viral Load; Zidovudine | 2000 |
Dose-finding study of once-daily indinavir/ritonavir plus zidovudine and lamivudine in HIV-infected patients.
Topics: Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Pilot Projects; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine | 2000 |
Pharmacological basis for concentration-controlled therapy with zidovudine, lamivudine, and indinavir.
Topics: Adult; Algorithms; Anti-HIV Agents; Area Under Curve; Drug Therapy, Combination; Female; Half-Life; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Patient Compliance; Zidovudine | 2001 |
A randomized, double-blind study of triple nucleoside therapy of abacavir, lamivudine, and zidovudine versus lamivudine and zidovudine in previously treated human immunodeficiency virus type 1-infected children. The CNAA3006 Study Team.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Confidence Intervals; Dideoxynucleosides; Disease Progression; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Growth; HIV-1; Humans; Infant; Lamivudine; Male; RNA, Viral; Zidovudine | 2001 |
Plasma population pharmacokinetics and penetration into cerebrospinal fluid of indinavir in combination with zidovudine and lamivudine in HIV-1-infected patients.
Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
Twice-daily triple nucleoside intensification treatment with lamivudine-zidovudine plus abacavir sustains suppression of human immunodeficiency virus type 1: results of the TARGET Study.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2001 |
Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection.
Topics: Adult; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine | 2001 |
Alterations in T cell phenotype and human immunodeficiency virus type 1-specific cytotoxicity after potent antiretroviral therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Epitopes, T-Lymphocyte; Flow Cytometry; HIV Infections; HIV-1; HLA-DR Antigens; Humans; Immunodominant Epitopes; Immunohistochemistry; Immunophenotyping; Indinavir; Lamivudine; Leukocyte Common Antigens; Prospective Studies; Protein Tyrosine Phosphatase, Non-Receptor Type 1; T-Lymphocytes, Cytotoxic; Viral Load; Zidovudine | 2001 |
Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial.
Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Resistance, Microbial; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Indinavir; Lamivudine; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Survival Analysis; Therapeutic Equivalency; Viral Load; Zidovudine | 2001 |
Long-term virologic and immunologic responses in human immunodeficiency virus type 1-infected children treated with indinavir, zidovudine, and lamivudine.
Topics: Adolescent; Anti-HIV Agents; CD4 Antigens; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Leukocyte Common Antigens; Male; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RNA, Viral; Viral Load; Zidovudine | 2001 |
Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection.
Topics: Adult; Anti-HIV Agents; Central Nervous System Diseases; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Motor Skills; Stavudine; Zalcitabine; Zidovudine | 2001 |
Abacavir/lamivudine/zidovudine as a combined formulation tablet: bioequivalence compared with each component administered concurrently and the effect of food on absorption.
Topics: Absorption; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Eating; Fasting; Female; Half-Life; Humans; Lamivudine; Male; Mass Spectrometry; Middle Aged; Reverse Transcriptase Inhibitors; Therapeutic Equivalency; Zidovudine | 2001 |
An open-label randomized trial to evaluate different therapeutic strategies of combination therapy in HIV-1 infection: design, rationale, and methods of the initio trial.
Topics: Adult; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Selection; Randomized Controlled Trials as Topic; Research Design; Ritonavir; Sample Size; Saquinavir; Stavudine; Zidovudine | 2001 |
A comparison of the steady-state pharmacokinetics and safety of abacavir, lamivudine, and zidovudine taken as a triple combination tablet and as abacavir plus a lamivudine-zidovudine double combination tablet by HIV-1-infected adults.
Topics: Adult; Area Under Curve; Cross-Over Studies; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Half-Life; HIV Infections; HIV-1; Humans; Lamivudine; Male; Metabolic Clearance Rate; Reverse Transcriptase Inhibitors; Tablets; Zidovudine | 2001 |
Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Multivariate Analysis; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine | 2001 |
Challenges of antiretroviral treatment in transient and drug-using populations: the SUN study.
Topics: Adult; Antiretroviral Therapy, Highly Active; Capsules; CD4 Lymphocyte Count; Chemistry, Pharmaceutical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Mental Disorders; Patient Compliance; Pilot Projects; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Saquinavir; Substance Abuse, Intravenous; Transients and Migrants; Treatment Outcome; Viral Load; Zidovudine | 2001 |
Open-label phase II trial of amprenavir, abacavir, and fixed-dose zidovudine/lamivudine in newly and chronically HIV-1--infected patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Chronic Disease; Dideoxynucleosides; Digestive System; Drug Synergism; Ethnicity; Female; Furans; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Subsets; Male; Pregnancy; Research Design; RNA, Viral; Sulfonamides; Treatment Refusal; Zidovudine | 2001 |
Loss of antiviral effect owing to zidovudine and lamivudine double resistance in HIV-1-infected patients in an ongoing open-label trial.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV-1; Humans; Lamivudine; Mutation; Phenotype; RNA, Viral; Zidovudine | 1997 |
Combination shows reduction in viral levels.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; HIV Seropositivity; Humans; Indinavir; Lamivudine; Time Factors; Zidovudine | 1996 |
Drug combination shows benefits for AIDS patients with history of taking AZT.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; HIV; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Zidovudine | 1996 |
Phase II/III Trials of Viracept start.
Topics: Anti-HIV Agents; Blood; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; Stavudine; Sulfonic Acids; Time Factors; Zidovudine | 1996 |
Research study of combination AIDS therapies underway.
Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Nevirapine; Pyridines; Zidovudine | 1996 |
Final CESARE trial results show continued clinical and survival benefit.
Topics: Acetamides; Acetophenones; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Survival Rate; Zalcitabine; Zidovudine | 1997 |
Preliminary data on 141W94 reported.
Topics: Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sulfonamides; Zidovudine | 1998 |
Phase III results presented on amprenavir triple combination.
Topics: Anti-HIV Agents; Carbamates; Drug Administration Schedule; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sulfonamides; Zidovudine | 1998 |
Merck protease inhibitor trial seeks persons with CD4 count under 50.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Industry; Drug Therapy, Combination; HIV Protease Inhibitors; Hotlines; Humans; Indinavir; Lamivudine; Patient Selection; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine | 1995 |
New protease inhibitor studies.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine | 1995 |
Treatment for primary infection.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Cohort Studies; Controlled Clinical Trials as Topic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Placebos; Pyridines; Ritonavir; Thiazoles; Valine; Zalcitabine; Zidovudine | 1995 |
New double vs. triple antiviral combination study, CD4 200-500, no prior treatment.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1995 |
Agouron starts phase III protease inhibitor studies.
Topics: Adolescent; Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Placebos; Zalcitabine; Zidovudine | 1996 |
Antiretroviral combination treatment prolongs life in people with HIV/AIDS.
Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1996 |
Protease inhibitors: major study stopped when 3-drug arm proves superior.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Treatment Outcome; Zidovudine | 1997 |
Major pediatric study stopped early: combination treatment better.
Topics: Anti-HIV Agents; Child; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine | 1997 |
Combination therapies improve outlook for children with HIV disease.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Lamivudine; Zidovudine | 1997 |
Delavirdine combination and viral load.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Delavirdine; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 1997 |
Lactic acid levels in children perinatally treated with antiretroviral agents to prevent HIV transmission.
Topics: Anti-HIV Agents; Cross-Sectional Studies; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lactic Acid; Lamivudine; Male; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
Low incidence of genotypic and phenotypic resistance in paediatric HIV-infected patients on long-term first-line antiretroviral triple therapy.
Topics: Adolescent; Child; Child, Preschool; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Ritonavir; Time; Viral Load; Zidovudine | 2001 |
A randomized, open-label, comparative trial of zidovudine plus lamivudine versus zidovudine plus lamivudine plus didanosine in antiretroviral-naive HIV-1-infected Thai patients.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Thailand; Treatment Outcome; Zidovudine | 2001 |
Durable HIV-1 suppression with indinavir after failing lamivudine-containing double nucleoside therapy: a randomized controlled trial.
Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; Follow-Up Studies; HIV-1; Humans; Indinavir; Lamivudine; Middle Aged; Prospective Studies; RNA, Viral; Zidovudine | 2001 |
Long-term protease inhibitor-containing therapy results in limited improvement in T cell function but not restoration of interleukin-12 production in pediatric patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Antigens; HIV Protease Inhibitors; Humans; Indinavir; Interleukin-12; Lamivudine; Male; Phytohemagglutinins; T-Lymphocytes; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2001 |
Pharmacokinetics of zidovudine and lamivudine in neonates following coadministration of oral doses every 12 hours.
Topics: Adult; Area Under Curve; Breast Feeding; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Female; Half-Life; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Metabolic Clearance Rate; Pregnancy; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2001 |
AVANTI 3: a randomized, double-blind trial to compare the efficacy and safety of lamivudine plus zidovudine versus lamivudine plus zidovudine plus nelfinavir in HIV-1-infected antiretroviral-naive patients.
Topics: Administration, Oral; Adult; Anti-HIV Agents; Clinical Protocols; Diarrhea; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nausea; Nelfinavir; Patient Compliance; RNA, Viral; Zidovudine | 2001 |
Treatment intensification with abacavir in HIV-infected patients with at least 12 weeks previous lamivudine/zidovudine treatment.
Topics: Administration, Oral; Adolescent; Adult; Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Time Factors; Zidovudine | 2001 |
Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression.
Topics: Adolescent; Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; Drug Therapy, Combination; Enzyme Inhibitors; Female; HIV Infections; Humans; Hydroxyurea; Indinavir; Lamivudine; Male; Nucleic Acid Synthesis Inhibitors; Pancreatitis; Prospective Studies; Survival Analysis; Treatment Failure; Viral Load; Zidovudine | 2001 |
Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine.
Topics: Adult; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
The effect of antiretroviral therapy on HTLV infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deltaretrovirus Infections; DNA, Viral; Drug Therapy, Combination; Female; HIV-1; Human T-lymphotropic virus 1; Human T-lymphotropic virus 2; Humans; Lamivudine; Male; Middle Aged; Proviruses; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2001 |
Triple nuke therapy--results after one year.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2001 |
Potential adverse effects of structured therapeutic interruptions on the pool of HIV-infected cells.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Disease Progression; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Morbidity; Prognosis; Ritonavir; RNA, Viral; Saquinavir; Viral Load; Zidovudine | 2001 |
Randomized, double-blind comparison of two nelfinavir doses plus nucleosides in HIV-infected patients (Agouron study 511).
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine | 2001 |
Predictors of virologic and clinical outcomes in HIV-1-infected patients receiving concurrent treatment with indinavir, zidovudine, and lamivudine. AIDS Clinical Trials Group Protocol 320.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Protocols; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Logistic Models; Male; Middle Aged; RNA, Viral; Viral Load; Zidovudine | 2001 |
Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations.
Topics: Anti-HIV Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Mutation; Stavudine; Treatment Failure; Zidovudine | 2001 |
Response to lamivudine-zidovudine plus abacavir twice daily in antiretroviral-naive, incarcerated patients with HIV infection taking directly observed treatment.
Topics: Adolescent; Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Therapy, Combination; Female; Health Care Costs; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Treatment Outcome; Zidovudine | 2002 |
Evidence of immune reconstitution in antiretroviral drug-experienced patients with advanced HIV disease.
Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cyclopropanes; Didanosine; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Concentration-controlled compared with conventional antiretroviral therapy for HIV infection.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Feasibility Studies; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 2002 |
Final analysis of the Trilège induction-maintenance trial: results at 18 months.
Topics: Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Multivariate Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Results of 2 years of treatment with protease-inhibitor--containing antiretroviral therapy in dutch children infected with human immunodeficiency virus type 1.
Topics: Adolescent; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Netherlands; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine | 2002 |
Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2002 |
[A clinical trial using zidovudine and lamivudine plus indinavir triple therapy in Chinese individuals with human immunodeficiency virus infection].
Topics: Adult; Aged; Anti-HIV Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; China; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Count; Male; Middle Aged; RNA, Viral; Time Factors; Treatment Outcome; Viremia; Zidovudine | 2002 |
Efficacy of three short-course regimens of zidovudine and lamivudine in preventing early and late transmission of HIV-1 from mother to child in Tanzania, South Africa, and Uganda (Petra study): a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Anti-HIV Agents; Breast Feeding; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Multicenter Studies as Topic; Pregnancy; Risk Factors; South Africa; Tanzania; Treatment Outcome; Uganda; Zidovudine | 2002 |
Therapeutic vaccination in primary HIV infection, the Quest trial.
Topics: AIDS Vaccines; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Carbamates; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Defective Viruses; Dideoxynucleosides; Furans; HIV Infections; Humans; Immunotherapy, Active; Lamivudine; Lymphocyte Count; Sulfonamides; T-Lymphocyte Subsets; Vaccination; Vaccinia virus; Viral Load; Viral Vaccines; Viremia; Zidovudine | 2002 |
A randomized trial of simplified maintenance therapy with abacavir, lamivudine, and zidovudine in human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV-1; Humans; Lamivudine; Lipids; Male; Prospective Studies; RNA, Viral; Treatment Failure; Viral Load; Zidovudine | 2002 |
Observations of HIV-1 genotypic drug resistance in a trial of four reverse transcriptase inhibitors (Quattro Trial).
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Viral Load; Zalcitabine; Zidovudine | 2002 |
Mutations in HIV-1 reverse transcriptase during therapy with abacavir, lamivudine and zidovudine in HIV-1-infected adults with no prior antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Zidovudine | 2002 |
Efficacy of zidovudine compared to stavudine, both in combination with lamivudine and indinavir, in human immunodeficiency virus-infected nucleoside-experienced patients with no prior exposure to lamivudine, stavudine, or protease inhibitors (novavir tria
Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Effect of combination antiretroviral therapy on cerebrospinal fluid HIV RNA, HIV resistance, and clinical manifestations of encephalopathy.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Child; Child, Preschool; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; HIV-1; Humans; Infant; Lamivudine; RNA, Viral; Statistics, Nonparametric; Viral Load; Zidovudine | 2002 |
Anti-HIV agents. Indinavir--3 years and still going strong.
Topics: Adipose Tissue; Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Viral Load; Zidovudine | 2000 |
The pharmacokinetics of amprenavir, zidovudine, and lamivudine in the genital tracts of men infected with human immunodeficiency virus type 1 (AIDS clinical trials group study 850).
Topics: Adult; Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; Genitalia, Male; HIV Infections; HIV-1; Humans; Lamivudine; Male; RNA, Viral; Semen; Statistics, Nonparametric; Sulfonamides; Zidovudine | 2002 |
Safety and efficacy of saquinavir soft-gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission.
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Safety; Saquinavir; Thailand; United Kingdom; Viremia; Zidovudine | 2002 |
A phase II randomized study of the virologic and immunologic effect of zidovudine + stavudine versus stavudine alone and zidovudine + lamivudine in patients with >300 CD4 cells who were antiretroviral naive (ACTG 298).
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Stavudine; Zidovudine | 2002 |
A randomized, open-label, comparative trial of BID and TID dosing of saquinavir enhanced oral formulation as part of a triple therapy for advanced AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Female; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Zidovudine | 2002 |
Adherence to antiretroviral therapy and outcomes in HIV-infected patients enrolled in an induction/maintenance randomized trial.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Patient Compliance; RNA, Viral; Treatment Outcome; Zidovudine | 2002 |
A randomized clinical trial comparing nelfinavir or nevirapine associated to zidovudine/lamivudine in HIV-infected naive patients (the Combine Study).
Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Argentina; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Nevirapine; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Treatment Outcome; Zidovudine | 2002 |
The efficacy of combined zidovudine and lamivudine compared with that of combined zidovudine, lamivudine and nelfinavir in asymptomatic and early symptomatic HIV-infected children.
Topics: CD4 Lymphocyte Count; Child, Preschool; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Thailand; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Efficacy and safety of a quadruple combination Combivir + abacavir + efavirenz regimen in antiretroviral treatment-naive HIV-1-infected adults: La Francilienne.
Topics: Administration, Oral; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; France; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Short-course therapy with zidovudine plus lamivudine for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Thailand.
Topics: Adolescent; Adult; Anti-HIV Agents; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Prospective Studies; Thailand; Zidovudine | 2002 |
Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Interactions; Drug Resistance, Viral; Female; HIV Infections; Humans; Hydroxyurea; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Nevirapine; Nucleosides; Phosphorylation; Reverse Transcriptase Inhibitors; Zidovudine | 2002 |
Increased risk of lipoatrophy under stavudine in HIV-1-infected patients: results of a substudy from a comparative trial.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Constitution; Body Mass Index; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Indinavir; Lamivudine; Male; Middle Aged; Risk Factors; Stavudine; Zidovudine | 2002 |
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mutation; Patient Compliance; RNA, Viral; Stavudine; Viral Load; Zidovudine | 2002 |
Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial).
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV-1; Humans; Lamivudine; Nelfinavir; Phenotype; RNA, Viral; Zidovudine | 2002 |
A multicenter randomized controlled trial of nevirapine versus a combination of zidovudine and lamivudine to reduce intrapartum and early postpartum mother-to-child transmission of human immunodeficiency virus type 1.
Topics: Adult; Anti-HIV Agents; Delivery, Obstetric; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Labor, Obstetric; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine | 2003 |
Genotype and phenotype at baseline and at failure in human immunodeficiency virus-infected antiretroviral-naive patients in a randomized trial comparing zidovudine and lamivudine plus nelfinavir or nevirapine.
Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Argentina; Cohort Studies; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Middle Aged; Mutation; Nelfinavir; Nevirapine; Phenotype; Reverse Transcriptase Inhibitors; Spain; Treatment Failure; Zidovudine | 2003 |
Greater reversal of CD4+ cell abnormalities and viral load reduction after initiation of antiretroviral therapy with zidovudine, lamivudine, and nelfinavir before complete HIV type 1 seroconversion.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Prospective Studies; RNA, Viral; Viral Load; Zidovudine | 2003 |
TRIZAL study: switching from successful HAART to Trizivir (abacavir-lamivudine-zidovudine combination tablet): 48 weeks efficacy, safety and adherence results.
Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Antiviral Agents; Chi-Square Distribution; Cholesterol; Dideoxynucleosides; Drug Combinations; Drug Hypersensitivity; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Protease Inhibitors; RNA, Viral; Statistics, Nonparametric; Triglycerides; Viral Load; Zidovudine | 2003 |
Triple nucleoside combination zidovudine/lamivudine/abacavir versus zidovudine/lamivudine/nelfinavir as first-line therapy in HIV-1-infected adults: a randomized trial.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Zidovudine | 2003 |
Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients.
Topics: Adult; Body Composition; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Stavudine; Zidovudine | 2003 |
Comparison of metabolic abnormalities 48 weeks after switching from highly active antiretroviral therapy containing a non-nucleoside reverse transcriptase inhibitor to Trizivir versus continued highly active antiretroviral therapy.
Topics: Antiretroviral Therapy, Highly Active; Cholesterol; Dideoxynucleosides; Drug Combinations; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine | 2003 |
Feeding risk cut for HIV-infected women.
Topics: Anti-HIV Agents; Breast Feeding; Didanosine; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Rwanda; Uganda; Zidovudine | 2003 |
Nucleoside analogue mutations and Q151M in HIV-1 subtype A/E infection treated with nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
Antiviral dynamics and sex differences of zidovudine and lamivudine triphosphate concentrations in HIV-infected individuals.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Female; Half-Life; HIV Infections; Humans; Immunoassay; Lamivudine; Male; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Severity of Illness Index; Sex Factors; Zidovudine | 2003 |
Long-term efficacy, safety, and tolerability of indinavir-based therapy in protease inhibitor-naive adults with advanced HIV infection.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; RNA, Viral; Zidovudine | 2003 |
Impact of an educational program on efficacy and adherence with a twice-daily lamivudine/zidovudine/abacavir regimen in underrepresented HIV-infected patients.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Patient Compliance; Patient Education as Topic; RNA, Viral; Zidovudine | 2003 |
Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2003 |
Field evaluation of an improved assay using a heat-dissociated p24 antigen for adults mainly infected with HIV-1 CRF02_AG strains in Côte d'Ivoire, West Africa.
Topics: Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Cote d'Ivoire; Drug Combinations; Enzyme-Linked Immunosorbent Assay; HIV Antibodies; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Middle Aged; Prospective Studies; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Sensitivity and Specificity; Zidovudine | 2003 |
MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study.
Topics: Adult; Alleles; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; Female; Genes, MDR; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Ritonavir; RNA, Viral; Zidovudine | 2003 |
Twice-daily Trizivir versus Combivir-abacavir in antiretroviral-experienced adults with human immunodeficiency virus-1 infection: a formulation-switch trial.
Topics: Adolescent; Adult; Analysis of Variance; Anti-HIV Agents; Chemistry, Pharmaceutical; Confidence Intervals; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Zidovudine | 2003 |
A pilot study to evaluate the safety and feasibility of the administration of AZT/3TC fixed dose combination to HIV infected pregnant women and their infants in Rio de Janeiro, Brazil.
Topics: Administration, Oral; Adult; Anti-HIV Agents; Brazil; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine | 2003 |
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Oxazines; RNA, Viral; Stavudine; Time Factors; Treatment Failure; Zidovudine | 2003 |
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nelfinavir; Oxazines; Stavudine; Time Factors; Treatment Failure; Zidovudine | 2003 |
Meeting notes from the 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment. Trizivir vs. efavirenz: results from ACTG 5095.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Oxazines; Placebos; Viral Load; Zidovudine | 2003 |
TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine | 2003 |
Detection of drug-resistant minority variants of HIV-1 during virologic failure of indinavir, lamivudine, and zidovudine.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Resistance, Viral; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Mutation; RNA, Viral; Zidovudine | 2004 |
Elective cesarean delivery plus short-course lamivudine and zidovudine for the prevention of mother-to-child transmission of human immunodeficiency virus type 1.
Topics: Adult; Anti-HIV Agents; Cesarean Section; Female; HIV Infections; HIV-1; Humans; Incidence; Infant, Newborn; Infant, Newborn, Diseases; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Viral Load; Zidovudine | 2004 |
Rate of thymidine analogue resistance mutation accumulation with zidovudine- or stavudine-based regimens.
Topics: Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Pharmacokinetic characteristics of ritonavir, zidovudine, lamivudine, and stavudine in children with human immunodeficiency virus infection.
Topics: Adolescent; Anti-HIV Agents; Area Under Curve; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; HIV Infections; Humans; Lamivudine; Male; Metabolic Clearance Rate; Ritonavir; Stavudine; Zidovudine | 2004 |
Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection.
Topics: Adult; Aged; Alkynes; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 2004 |
Immune restoration in HIV-positive, antiretroviral-naive patients after 1 year of zidovudine/lamivudine plus nelfinavir or nevirapine.
Topics: Adult; Aged; Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Lamivudine; Lymphocyte Activation; Male; Middle Aged; Nelfinavir; Nevirapine; Reverse Transcriptase Inhibitors; T-Lymphocyte Subsets; Zidovudine | 2004 |
A rapid and sensitive method for simultaneous determination of lamivudine and zidovudine in human serum by on-line solid-phase extraction coupled to liquid chromatography/tandem mass spectrometry detection.
Topics: Adult; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Therapeutic Equivalency; Zidovudine | 2004 |
Three-year durability of dual-nucleoside versus triple-nucleoside therapy in a Thai population with HIV infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; RNA, Viral; Stavudine; Thailand; Time Factors; Zidovudine | 2004 |
Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose zidovudine and lamivudine, as initial therapy for patients infected with HIV.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Oligopeptides; Oxazines; Pyridines; RNA, Viral; Zidovudine | 2004 |
Triple nucleoside treatment with abacavir plus the lamivudine/zidovudine combination tablet (COM) compared to indinavir/COM in antiretroviral therapy-naïve adults: results of a 48-week open-label, equivalence trial (CNA3014).
Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Patient Compliance; Reverse Transcriptase Inhibitors; RNA; Surveys and Questionnaires; Therapeutic Equivalency; Treatment Outcome; Zidovudine | 2004 |
Predictors of adherence and virologic outcome in HIV-infected patients treated with abacavir- or indinavir-based triple combination HAART also containing lamivudine/zidovudine.
Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Patient Compliance; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Outcome; Zidovudine | 2004 |
Once-daily versus twice-daily lamivudine, in combination with zidovudine and efavirenz, for the treatment of antiretroviral-naive adults with HIV infection: a randomized equivalence trial.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2004 |
Impact of indinavir on the quality of life in patients with advanced HIV infection treated with zidovudine and lamivudine.
Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Quality of Life; Reverse Transcriptase Inhibitors; Sickness Impact Profile; Survival Analysis; Zidovudine | 2004 |
HIV-1 drug resistance in subjects with advanced HIV-1 infection in whom antiretroviral combination therapy is failing: a substudy of AIDS Clinical Trials Group Protocol 388.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Phenotype; Stavudine; Treatment Failure; Zidovudine | 2004 |
Abacavir versus zidovudine combined with lamivudine and efavirenz, for the treatment of antiretroviral-naive HIV-infected adults.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Oxazines; RNA, Viral; Zidovudine | 2004 |
New once-daily HIV combination better tolerated.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Oxazines; Tenofovir; Zidovudine | 2004 |
Persistent antiretroviral activity of nucleoside analogues after prolonged zidovudine and lamivudine therapy as demonstrated by rapid loss of activity after discontinuation.
Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Zidovudine | 2004 |
A randomized study comparing a three- and four-drug HAART regimen in first-line therapy (QUAD study).
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Lamivudine; Oxazines; Viral Load; Zidovudine | 2005 |
Tolerability of postexposure prophylaxis with the combination of zidovudine-lamivudine and lopinavir-ritonavir for HIV infection.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; Viral Load; Zidovudine | 2005 |
Tenofovir regimen compared with Combivir.
Topics: Adenine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Europe; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Maximum Tolerated Dose; Organophosphonates; Risk Assessment; Severity of Illness Index; Single-Blind Method; Tenofovir; Treatment Outcome; United States; Viral Load; Zidovudine | 2005 |
Efficacy of tenofovir as intensification of zidovudine/lamivudine/abacavir fixed-dose combination in the treatment of HIV-positive patients.
Topics: CD4 Lymphocyte Count; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; RNA, Viral; Viral Load; Zidovudine | 2005 |
Field assessment of generic antiretroviral drugs: a prospective cohort study in Cameroon.
Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Drugs, Generic; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2005 |
Spontaneous recovery of hemoglobin and neutrophil levels in Japanese patients on a long-term Combivir containing regimen.
Topics: Adult; Aged; Anti-HIV Agents; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; HIV Infections; Humans; Japan; Lamivudine; Leukocyte Count; Male; Middle Aged; Neutrophils; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome; Zidovudine | 2005 |
Induction with abacavir/lamivudine/zidovudine plus efavirenz for 48 weeks followed by 48-week maintenance with abacavir/lamivudine/zidovudine alone in antiretroviral-naive HIV-1-infected patients.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Patient Compliance; RNA, Viral; Zidovudine | 2005 |
Antiretroviral treatment simplification with 3 NRTIs or 2 NRTIs plus nevirapine in HIV-1-infected patients treated with successful first-line HAART.
Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Patient Compliance; Patient Satisfaction; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 2005 |
Results of the ALBI trial: a randomized comparison of stavudine/didanosine, zidovudine/lamivudine and alternating treatment in antiretroviral-naive patients.
Topics: Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1999 |
Effects on immunological and virological outcome of patients using one protease inhibitor or one non-nucleoside reverse transcriptase inhibitor in a triple antiretroviral therapy: normal clinical practice versus clinical trial findings.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Oxazines; Retrospective Studies; Treatment Outcome; Tunisia; Viremia; Zidovudine | 2005 |
Antiretroviral concentrations in breast-feeding infants of women in Botswana receiving antiretroviral treatment.
Topics: Adult; Anti-HIV Agents; Botswana; Breast Feeding; Female; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lactation; Lamivudine; Milk, Human; Nevirapine; Reverse Transcriptase Inhibitors; Statistics, Nonparametric; Zidovudine | 2005 |
Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age.
Topics: Age Factors; Antiretroviral Therapy, Highly Active; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Lamivudine; Male; Maximum Tolerated Dose; Prospective Studies; Risk Assessment; Ritonavir; Severity of Illness Index; Single-Blind Method; Survival Rate; Treatment Outcome; Zidovudine | 2005 |
Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study.
Topics: Adult; Area Under Curve; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribavirin; Stavudine; Time Factors; Zidovudine | 2005 |
Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors.
Topics: Adult; Aspartic Acid; Brain; Cell Respiration; Didanosine; Female; HIV Infections; Humans; Lamivudine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Mitochondrial Diseases; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 2005 |
Body fat and other metabolic effects of atazanavir and efavirenz, each administered in combination with zidovudine plus lamivudine, in antiretroviral-naive HIV-infected patients.
Topics: Adiposity; Adult; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Oligopeptides; Oxazines; Pyridines; Zidovudine | 2006 |
A randomized crossover study to determine bioequivalence of generic and brand name nevirapine, zidovudine, and lamivudine in HIV-negative women in India.
Topics: Administration, Oral; Adult; Anti-HIV Agents; Cohort Studies; Confidence Intervals; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Female; HIV Infections; HIV Seronegativity; Humans; India; Lamivudine; Nevirapine; Tablets; Therapeutic Equivalency; Zidovudine | 2006 |
A prospective, 96-week study of the impact of Trizivir, Combivir/nelfinavir, and lamivudine/stavudine/nelfinavir on lipids, metabolic parameters and efficacy in antiretroviral-naive patients: effect of sex and ethnicity.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Black or African American; CD4 Lymphocyte Count; Cholesterol; Dideoxynucleosides; Drug Combinations; Female; Hispanic or Latino; HIV Infections; HIV-1; Humans; Hyperlipidemias; Lactic Acid; Lamivudine; Male; Nelfinavir; Nevirapine; Prospective Studies; Sex Factors; Stavudine; Treatment Outcome; Triglycerides; Zidovudine | 2006 |
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV.
Topics: Adenine; Adolescent; Adult; Aged; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Oxazines; Prospective Studies; RNA, Viral; Tenofovir; Zidovudine | 2006 |
An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Organophosphonates; Oxazines; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Zidovudine | 2006 |
[Clinical trial comparing efficacy and safety of four highly active antiretroviral therapy (HAART) in antiretroviral-naive treatment with advanced HIV infection].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Disease Progression; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Ritonavir; Stavudine; Zidovudine | 2006 |
Boosted versus unboosted indinavir with zidovudine and lamivudine in nucleoside pre-treated patients: a randomized, open-label trial with 112 weeks of follow-up (HIV-NAT 005).
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Ritonavir; RNA, Viral; Time Factors; Viral Load; Zidovudine | 2006 |
Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa.
Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Developing Countries; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; RNA, Viral; Tenofovir; Treatment Outcome; Uganda; Viral Load; Zidovudine; Zimbabwe | 2006 |
Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: a pilot study.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Black People; Cytochrome P-450 CYP3A; DNA Primers; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Mitochondrial Proteins; Multidrug Resistance-Associated Proteins; Pharmacogenetics; Pilot Projects; Retrospective Studies; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Zidovudine | 2006 |
Postexposure prophylaxis for HIV in children and adolescents after sexual assault: a prospective observational study in an urban medical center.
Topics: Adolescent; Adult; Anti-HIV Agents; Child; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; New York City; Patient Compliance; Prospective Studies; Regression Analysis; Sex Offenses; Zidovudine | 2007 |
Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana.
Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Botswana; Drug Administration Schedule; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Nevirapine; Postpartum Period; Treatment Outcome; Zidovudine | 2006 |
Pharmacokinetics of a once-daily regimen of lopinavir/ritonavir in HIV-1-infected children.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Male; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Zidovudine | 2006 |
Initiation of antiretroviral treatment with dual nucleoside reverse transcriptase inhibitors in human immunodeficiency virus-infected infants with less advanced disease in a resource-limited setting: a multi-center study in Thailand 1998-2000.
Topics: Developing Countries; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine | 2005 |
Three- vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial.
Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; RNA, Messenger; Viral Load; Zidovudine | 2006 |
Zidovudine plus lamivudine in Human T-Lymphotropic Virus type-I-associated myelopathy: a randomised trial.
Topics: Aged; Anti-HIV Agents; Cell Proliferation; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; Paraparesis, Tropical Spastic; Placebos; Viral Load; Zidovudine | 2006 |
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic, immunologic, and morphologic changes--a 96-week analysis.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Oxazines; RNA, Viral; Tenofovir; Time Factors; Viral Load; Zidovudine | 2006 |
Virologic response of zidovudine, lamivudine, and tenofovir disoproxil fumarate combination in antiretroviral-naive HIV-1-infected patients.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Tenofovir; Viral Load; Zidovudine | 2006 |
Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV; HIV Infections; Humans; Lamivudine; Milk, Human; Nevirapine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; RNA, Viral; Stavudine; Zidovudine | 2007 |
Two-year morbidity-mortality and alternatives to prolonged breast-feeding among children born to HIV-infected mothers in Côte d'Ivoire.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; Cohort Studies; Cote d'Ivoire; Female; HIV Infections; Humans; Infant; Infant Formula; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Morbidity; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Time Factors; Treatment Outcome; Zidovudine | 2007 |
Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095).
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Blood Glucose; Body Composition; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Insulin Resistance; Lactic Acid; Lamivudine; Lipids; Male; Reverse Transcriptase Inhibitors; Zidovudine | 2007 |
Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy.
Topics: Adult; Anti-HIV Agents; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Leukocytes, Mononuclear; Logistic Models; Male; Reverse Transcriptase Inhibitors; Stavudine; Surveys and Questionnaires; Time Factors; Zidovudine | 2007 |
Antiretroviral efficacy and virological profile of a zidovudine/lamivudine/tenofovir disoproxil fumarate combination therapy in antiretroviral-naive patients.
Topics: Adenine; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Mutation; Organophosphonates; Pilot Projects; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Treatment Outcome; Zidovudine | 2006 |
Exploratory study comparing the metabolic toxicities of a lopinavir/ritonavir plus saquinavir dual protease inhibitor regimen versus a lopinavir/ritonavir plus zidovudine/lamivudine nucleoside regimen.
Topics: Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Pyrimidinones; Ritonavir; Saquinavir; Zidovudine | 2007 |
Plasma HIV-1 RNA dynamics in antiretroviral-naive subjects receiving either triple-nucleoside or efavirenz-containing regimens: ACTG A5166s.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Prospective Studies; Regression Analysis; RNA, Viral; Time Factors; Zidovudine | 2007 |
In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children.
Topics: Anti-HIV Agents; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Reverse Transcriptase; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Maternal-Fetal Exchange; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Factors; Zidovudine | 2007 |
Lamivudine/abacavir maintains virological superiority over zidovudine/lamivudine and zidovudine/abacavir beyond 5 years in children.
Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Dideoxynucleosides; Drug Resistance, Viral; Follow-Up Studies; Growth; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2007 |
Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384.
Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Didanosine; Double-Blind Method; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Nelfinavir; Prospective Studies; Stavudine; Testosterone; Zidovudine | 2007 |
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.
Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Composition; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Time Factors; Treatment Outcome; United States; Zidovudine | 2007 |
Population pharmacokinetic analysis of lamivudine, stavudine and zidovudine in controlled HIV-infected patients on HAART.
Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Interactions; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Models, Biological; Nelfinavir; Reverse Transcriptase Inhibitors; Stavudine; Tissue Distribution; Zidovudine | 2007 |
A comparison of three initial antiretroviral AIDS regimens.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; HIV; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 2007 |
144-week data released on Gilead's study 934.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Time Factors; Viral Load; Zidovudine | 2007 |
Pharmacokinetics of lamivudine, zidovudine, and nevirapine administered as a fixed-dose combination formulation versus coadministration of the individual products.
Topics: Adolescent; Adult; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine | 2007 |
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis.
Topics: Adenine; Adult; Alkynes; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2008 |
Antiretroviral therapy using zidovudine, lamivudine, and efavirenz in South Africa: tolerability and clinical events.
Topics: Adult; Alkynes; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Developing Countries; Dizziness; Drug Tolerance; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nausea; Neutropenia; Prospective Studies; South Africa; Treatment Outcome; Viral Load; Vomiting; Zidovudine | 2008 |
Zidovudine/lamivudine contributes to insulin resistance within 3 months of starting combination antiretroviral therapy.
Topics: Adiponectin; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Glucose; Glycerol; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Hyperinsulinism; Insulin Resistance; Lamivudine; Lipid Metabolism; Lipids; Lopinavir; Male; Middle Aged; Pyrimidinones; Time Factors; Treatment Outcome; Zidovudine | 2008 |
Induction therapy with trizivir plus efavirenz or lopinavir/ritonavir followed by trizivir alone in naive HIV-1-infected adults.
Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Failure; Treatment Outcome; Zidovudine | 2008 |
Lopinavir/ritonavir monotherapy or plus zidovudine and lamivudine in antiretroviral-naive HIV-infected patients.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease; HIV-1; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Twenty-four-week safety and tolerability of nevirapine vs. abacavir in combination with zidovudine/lamivudine as first-line antiretroviral therapy: a randomized double-blind trial (NORA).
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Treatment Outcome; Uganda; Zidovudine | 2008 |
Tolerability and effectiveness of first-line regimens combining nevirapine and lamivudine plus zidovudine or stavudine in Cameroon.
Topics: Adult; Anemia; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Multivariate Analysis; Nevirapine; Patient Compliance; Peripheral Nervous System Diseases; Prospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Effect of maraviroc on the pharmacokinetics of midazolam, lamivudine/zidovudine, and ethinyloestradiol/levonorgestrel in healthy volunteers.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anti-HIV Agents; CCR5 Receptor Antagonists; Contraceptives, Oral; Cyclohexanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; HIV Infections; Humans; Lamivudine; Levonorgestrel; Male; Maraviroc; Midazolam; Middle Aged; Statistics as Topic; Triazoles; Zidovudine | 2008 |
Absence of HIV-1 shedding in male genital tract after 1 year of first-line lopinavir/ritonavir alone or in combination with zidovudine/lamivudine.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Genitalia, Male; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Lopinavir; Male; Plasma; Pyrimidinones; Ritonavir; RNA, Viral; Semen; Time Factors; Virus Shedding; Zidovudine | 2008 |
Pharmacokinetics of zidovudine and lamivudine during oral uridine supplementation with NucleomaxX.
Topics: Administration, Oral; Area Under Curve; Double-Blind Method; Female; HIV Infections; Humans; Lamivudine; Male; Placebos; Reverse Transcriptase Inhibitors; Uridine; Zidovudine | 2008 |
Long-term subcutaneous tissue changes among antiretroviral-naive persons initiating stavudine, zidovudine, or abacavir with lamivudine.
Topics: Adult; Cohort Studies; Dideoxynucleosides; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Subcutaneous Fat; Zidovudine | 2008 |
Antiviral activity and safety of aplaviroc with lamivudine/zidovudine in HIV-infected, therapy-naive patients: the ASCENT (CCR102881) study.
Topics: Adult; Aged; Anti-HIV Agents; Benzoates; Diketopiperazines; Double-Blind Method; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Piperazines; Reverse Transcriptase Inhibitors; Spiro Compounds; Treatment Outcome; Zidovudine | 2008 |
Changes in antioxidant profile among HIV-infected individuals on generic highly active antiretroviral therapy in southern India.
Topics: Adult; Albumins; Alkynes; Anti-HIV Agents; Antioxidants; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Drugs, Generic; Female; Glutathione Peroxidase; Glutathione Reductase; HIV Infections; Humans; India; Lamivudine; Male; Oxidative Stress; Reverse Transcriptase Inhibitors; Stavudine; Uric Acid; Young Adult; Zidovudine | 2008 |
Clinical trial: randomized controlled study of zidovudine and lamivudine for patients with primary biliary cirrhosis stabilized on ursodiol.
Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Antiviral Agents; Aspartate Aminotransferases; Betaretrovirus; Cholagogues and Choleretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamivudine; Liver Cirrhosis, Biliary; Male; Middle Aged; Retroviridae Infections; Treatment Outcome; Tumor Virus Infections; Ursodeoxycholic Acid; Zidovudine | 2008 |
Zidovudine/lamivudine/abacavir plus tenofovir in HIV-infected naive patients: a 96-week prospective one-arm pilot study.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Endpoint Determination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Prospective Studies; Spain; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Effect of lopinavir/ritonavir monotherapy on quality of life and self-reported symptoms among antiretroviral-naive patients: results of the MONARK trial.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Pyrimidinones; Quality of Life; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brachial Artery; CD4 Lymphocyte Count; Cyclopropanes; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Time Factors; Zidovudine | 2008 |
A randomized trial of combination hepatitis B therapy in HIV/HBV coinfected antiretroviral naïve individuals in Thailand.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; DNA, Viral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir; Thailand; Treatment Outcome; Zidovudine | 2008 |
Didanosine, lamivudine, and efavirenz versus zidovudine, lamivudine, and efavirenz for the initial treatment of HIV type 1 infection: final analysis (48 weeks) of a prospective, randomized, noninferiority clinical trial, GESIDA 3903.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; RNA, Viral; Severity of Illness Index; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Phase II study of vicriviroc versus efavirenz (both with zidovudine/lamivudine) in treatment-naive subjects with HIV-1 infection.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Piperazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Highly active antiretroviral therapy versus zidovudine/nevirapine effects on early breast milk HIV type-1 Rna: a phase II randomized clinical trial.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral; Treatment Outcome; Zidovudine | 2008 |
Early antiretroviral therapy and mortality among HIV-infected infants.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; Treatment Failure; Zidovudine | 2008 |
Development of fixed dose combination tablets containing zidovudine and lamivudine for paediatric applications.
Topics: Adult; Anti-HIV Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Compounding; Female; Humans; Lamivudine; Male; Middle Aged; Pediatrics; Reverse Transcriptase Inhibitors; Solubility; Tablets; Zidovudine | 2009 |
Virologic failure in first-line human immunodeficiency virus therapy with a CCR5 entry inhibitor, aplaviroc, plus a fixed-dose combination of lamivudine-zidovudine: nucleoside reverse transcriptase inhibitor resistance regardless of envelope tropism.
Topics: Anti-HIV Agents; Benzoates; Diketopiperazines; Drug Combinations; Drug Resistance, Viral; env Gene Products, Human Immunodeficiency Virus; HIV Infections; HIV-1; Humans; Lamivudine; Phylogeny; Piperazines; Receptors, CCR5; Reverse Transcriptase Inhibitors; Spiro Compounds; Treatment Failure; Tropism; Zidovudine | 2009 |
A randomized, open-label study of a nucleoside analogue reverse transcriptase inhibitor-sparing regimen in antiretroviral-naive HIV-infected patients.
Topics: Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Male; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine | 2009 |
Predictors of loss of virologic response in subjects who simplified to lopinavir/ritonavir monotherapy from lopinavir/ritonavir plus zidovudine/lamivudine.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Medication Adherence; Plasma; Pyrimidinones; Ritonavir; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2009 |
First line zidovudine/lamivudine/lopinavir/ritonavir leads to greater bone loss compared to nevirapine/lopinavir/ritonavir.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Osteoporosis; Pyrimidinones; Ritonavir; Young Adult; Zidovudine | 2009 |
Protease inhibitor resistance analysis in the MONARK trial comparing first-line lopinavir-ritonavir monotherapy to lopinavir-ritonavir plus zidovudine and lamivudine triple therapy.
Topics: Drug Resistance, Viral; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Pyrimidinones; Ritonavir; Treatment Outcome; Zidovudine | 2009 |
Zidovudine/lamivudine for HIV-1 infection contributes to limb fat loss.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Biomarkers; Body Composition; Glucose; HIV Infections; HIV-1; Humans; Lamivudine; Lipids; Lipodystrophy; Lopinavir; Male; Middle Aged; Pyrimidinones; Zidovudine | 2009 |
Loss of bone mineral density after antiretroviral therapy initiation, independent of antiretroviral regimen.
Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Bone Density; Cyclopropanes; Female; HIV Infections; Humans; Inflammation Mediators; Lamivudine; Lopinavir; Male; Middle Aged; Osteoporosis; Prospective Studies; Pyrimidinones; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Risk Factors; Ritonavir; Zidovudine | 2009 |
Switch from a ZDV/3TC-based regimen to a completely once daily (QD) regimen of emtricitabine/tenofovir DF fixed dose combination plus a third QD agent (SONETT).
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Emtricitabine; Female; Hemoglobins; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load; Young Adult; Zidovudine | 2009 |
A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals.
Topics: Adenine; Adipose Tissue; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Extremities; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lipids; Male; Middle Aged; Organophosphonates; Tenofovir; Young Adult; Zidovudine | 2009 |
Modulation of K65R selection by zidovudine inclusion: analysis of HIV resistance selection in subjects with virologic failure receiving once-daily abacavir/lamivudine/zidovudine and tenofovir DF (study COL40263).
Topics: Adenine; Adult; Amino Acid Substitution; Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; RNA, Viral; Tenofovir; Treatment Failure; Zidovudine | 2009 |
Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.
Topics: Adult; AIDS-Related Opportunistic Infections; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Female; Ghana; Glucuronides; Glucuronosyltransferase; Half-Life; HIV Infections; Humans; Lamivudine; Liver; Male; Middle Aged; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Stavudine; Tuberculosis; Zidovudine | 2009 |
Development of HIV-1 drug resistance through 144 weeks in antiretroviral-naïve subjects on emtricitabine, tenofovir disoproxil fumarate, and efavirenz compared with lamivudine/zidovudine and efavirenz in study GS-01-934.
Topics: Adenine; Alkynes; Amino Acid Substitution; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genome, Viral; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Mutation, Missense; Organophosphonates; Tenofovir; Treatment Failure; Zidovudine | 2009 |
Long-term (96-week) follow-up of antiretroviral-naïve HIV-infected patients treated with first-line lopinavir/ritonavir monotherapy in the MONARK trial.
Topics: Antiretroviral Therapy, Highly Active; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Intention to Treat Analysis; Lamivudine; Lopinavir; Male; Medication Adherence; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome; Zidovudine | 2010 |
96-Week MERIT ES analysis shows efficacy of Celsentri=Selzentry.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Maraviroc; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome; Triazoles; Zidovudine | 2009 |
Pharmacokinetics and 48 week efficacy of low-dose lopinavir/ritonavir in HIV-infected children.
Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Plasma; Pyrimidinones; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2009 |
Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trial.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Viral Load; Zidovudine | 2009 |
Insulin sensitivity in multiple pathways is differently affected during zidovudine/lamivudine-containing compared with NRTI-sparing combination antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Blood Glucose; Body Composition; Drug Therapy, Combination; HIV Infections; Humans; Insulin Resistance; Intra-Abdominal Fat; Lamivudine; Lipids; Lipolysis; Liver; Male; Middle Aged; Zidovudine | 2010 |
Viral rebound and emergence of drug resistance in the absence of viral load testing: a randomized comparison between zidovudine-lamivudine plus Nevirapine and zidovudine-lamivudine plus Abacavir.
Topics: Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Mutation; Nevirapine; RNA, Viral; Uganda; Viral Load; Zidovudine | 2010 |
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine | 2009 |
Early versus delayed fixed dose combination abacavir/lamivudine/zidovudine in patients with HIV and tuberculosis in Tanzania.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Male; Pilot Projects; Tanzania; Tuberculosis; Viral Load; Zidovudine | 2009 |
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial.
Topics: Adenine; Adolescent; Adult; Africa; Aged; Anemia; Anti-Retroviral Agents; CD4 Lymphocyte Count; Creatinine; Dideoxynucleosides; Disease Progression; Drug Monitoring; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Neutropenia; Neutrophils; Nevirapine; Organophosphonates; RNA, Viral; Tenofovir; Urea; Viral Load; Zidovudine | 2010 |
Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months.
Topics: Adenine; Adipocytes; Adipose Tissue; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Differentiation; Cyclopropanes; Drug Therapy, Combination; Fatty Acids; Female; Gene Expression; Genes, Mitochondrial; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Up-Regulation; Zidovudine | 2009 |
The impact of once-nightly versus twice-daily dosing and baseline beliefs about HAART on adherence to efavirenz-based HAART over 48 weeks: the NOCTE study.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Culture; Cyclopropanes; Didanosine; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Surveys and Questionnaires; Zidovudine | 2010 |
Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts.
Topics: Adult; Body Weight; CD4 Lymphocyte Count; Dideoxynucleosides; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Nevirapine; Recurrence; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Uganda; Viral Load; Zidovudine | 2010 |
Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antiviral Agents; Benzoxazines; CCR5 Receptor Antagonists; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug Combinations; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Maraviroc; Middle Aged; Receptors, CCR5; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult; Zidovudine | 2010 |
Lack of minority K65R-resistant viral populations detected after repeated treatment interruptions of tenofovir/zidovudine and lamivudine in a resource-limited setting.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Viral Load; Zidovudine | 2010 |
Abacavir/lamivudine/zidovudine maintenance after standard induction in antiretroviral therapy-naïve patients: FREE randomized trial interim results.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Young Adult; Zidovudine | 2010 |
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV Infections; HIV Seronegativity; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Kaplan-Meier Estimate; Lamivudine; Male; Neutropenia; Nevirapine; Pregnancy; Risk Factors; Stevens-Johnson Syndrome; Young Adult; Zidovudine | 2010 |
Bone mineral density changes in protease inhibitor-sparing vs. nucleoside reverse transcriptase inhibitor-sparing highly active antiretroviral therapy: data from a randomized trial.
Topics: Absorptiometry, Photon; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Bone Density; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; Zidovudine | 2011 |
Safety and effectiveness of antiretroviral drugs during pregnancy, delivery and breastfeeding for prevention of mother-to-child transmission of HIV-1: the Kesho Bora Multicentre Collaborative Study rationale, design, and implementation challenges.
Topics: Africa, Eastern; Africa, Southern; Africa, Western; Anti-Retroviral Agents; Breast Feeding; Child, Preschool; Clinical Protocols; Cohort Studies; Delivery, Obstetric; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Mothers; Nevirapine; Pregnancy; Pyrimidinones; Research Design; Ritonavir; Zidovudine | 2011 |
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.
Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; RNA, Viral; South Africa; Stavudine; Treatment Outcome; Zidovudine | 2010 |
Long-term effectiveness and safety of didanosine combined with lamivudine and efavirenz or nevirapine in antiretroviral-naive patients: a 9-year cohort study in Senegal.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Treatment Outcome; Viral Load; Zidovudine | 2011 |
Evaluation of steady-state pharmacokinetic interactions between ritonavir-boosted BILR 355, a non-nucleoside reverse transcriptase inhibitor, and lamivudine/zidovudine in healthy subjects.
Topics: Adult; Anti-HIV Agents; Area Under Curve; Azepines; Drug Combinations; Drug Interactions; Female; Half-Life; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Young Adult; Zidovudine | 2012 |
Fat tissue distribution changes in HIV-infected patients treated with lopinavir/ritonavir. Results of the MONARK trial.
Topics: Absorptiometry, Photon; Adult; Anti-HIV Agents; Body Fat Distribution; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Pyrimidinones; Ritonavir; Zidovudine | 2011 |
Beliefs about antiretroviral therapy, treatment adherence and quality of life in a 48-week randomised study of continuation of zidovudine/lamivudine or switch to tenofovir DF/emtricitabine, each with efavirenz.
Topics: Adenine; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Substitution; Drug Therapy, Combination; Emtricitabine; Female; Health Knowledge, Attitudes, Practice; HIV Infections; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Organophosphonates; Quality of Life; Tenofovir; Treatment Outcome; Young Adult; Zidovudine | 2011 |
Timing of initiation of antiretroviral therapy in human immunodeficiency virus (HIV)--associated tuberculous meningitis.
Topics: Adult; Alkynes; Anti-HIV Agents; Anti-Inflammatory Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Benzoxazines; Cyclopropanes; Dexamethasone; Double-Blind Method; Female; HIV Infections; Humans; Lamivudine; Male; Placebos; Time Factors; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Meningeal; Zidovudine | 2011 |
Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; HIV Infections; Lamivudine; Lopinavir; Protease Inhibitors; Ritonavir; Stavudine; Zidovudine | 2011 |
Residual activity of two HIV antiretroviral regimens prescribed without virological monitoring.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Lamivudine; Nevirapine; RNA, Viral; Viral Load; Zidovudine | 2011 |
A randomized trial of punctuated antiretroviral therapy in Ugandan HIV-seropositive adults with pulmonary tuberculosis and CD4⁺ T-cell counts of ≥ 350 cells/μL.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Dideoxynucleosides; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Survival Analysis; Treatment Outcome; Tuberculosis, Pulmonary; Uganda; Young Adult; Zidovudine | 2011 |
Glomerular dysfunction and associated risk factors over 4-5 years following antiretroviral therapy initiation in Africa.
Topics: Adenine; Adult; Africa; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Creatinine; Dideoxynucleosides; Female; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Diseases; Kidney Glomerulus; Lamivudine; Male; Nevirapine; Organophosphonates; Risk Factors; Tenofovir; Time Factors; Zidovudine | 2011 |
Pharmacokinetics and safety of a new paediatric fixed-dose combination of zidovudine/lamivudine/nevirapine in HIV-infected children.
Topics: Anti-HIV Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biological Availability; Body Weight; Child; Child, Preschool; Cytochrome P-450 CYP2B6; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Oxidoreductases, N-Demethylating; Reverse Transcriptase Inhibitors; Tablets; Zidovudine | 2011 |
Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in women.
Topics: Anti-HIV Agents; Drug Combinations; Drug Resistance, Viral; Female; Genotype; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral; Viral Load; Zidovudine | 2012 |
Post-exposure prophylaxis for HIV infection: a clinical trial comparing lopinavir/ritonavir versus atazanavir each with zidovudine/lamivudine.
Topics: Adult; Anti-HIV Agents; Atazanavir Sulfate; Drug Combinations; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Oligopeptides; Post-Exposure Prophylaxis; Pyridines; Ritonavir; Zidovudine | 2012 |
Effect of gender and race on the week 48 findings in treatment-naïve, HIV-1-infected patients enrolled in the randomized, phase III trials ECHO and THRIVE.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black or African American; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Sex Factors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2012 |
A comparison of measured and estimated glomerular filtration rate in successfully treated HIV-patients with preserved renal function.
Topics: Adenine; Adult; Anti-HIV Agents; Body Mass Index; Deoxycytidine; Emtricitabine; Female; Glomerular Filtration Rate; HIV Infections; Humans; Lamivudine; Linear Models; Male; Middle Aged; Netherlands; Organophosphonates; Pilot Projects; Research Design; Statistics, Nonparametric; Tenofovir; Treatment Outcome; Zidovudine | 2012 |
Maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission: 48-week follow-up of the BAN randomised controlled trial.
Topics: Adult; Anti-Retroviral Agents; Breast Feeding; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Young Adult; Zidovudine | 2012 |
Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial.
Topics: Abortion, Spontaneous; Adenine; Adult; Anti-HIV Agents; Body Height; Body Weight; Breast Feeding; Burns; Cause of Death; Child, Preschool; Congenital Abnormalities; Drug Combinations; Female; Follow-Up Studies; Fractures, Bone; Growth; HIV Infections; HIV Seropositivity; Humans; Infant; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Measles; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prevalence; Respiratory Tract Infections; Tenofovir; Uganda; Zidovudine; Zimbabwe | 2012 |
Three postpartum antiretroviral regimens to prevent intrapartum HIV infection.
Topics: Anti-Retroviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant Formula; Infant, Newborn; Infectious Disease Transmission, Vertical; Kaplan-Meier Estimate; Lamivudine; Male; Nelfinavir; Nevirapine; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 2012 |
Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children.
Topics: Anti-Retroviral Agents; CD4 Lymphocyte Count; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Kaplan-Meier Estimate; Lamivudine; Lopinavir; Male; Nevirapine; Ritonavir; RNA, Viral; Zidovudine | 2012 |
Treatment outcomes among HIV-1 and HIV-2 infected children initiating antiretroviral therapy in a concentrated low prevalence setting in West Africa.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; Gambia; HIV Infections; HIV-1; HIV-2; Humans; Infant; Kaplan-Meier Estimate; Lamivudine; Lopinavir; Male; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Viral Load; Zidovudine | 2012 |
Zidovudine/lamivudine but not nevirapine in combination with lopinavir/ritonavir decreases subcutaneous adipose tissue mitochondrial DNA.
Topics: Absorptiometry, Photon; Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Anti-HIV Agents; Atrophy; CD4 Lymphocyte Count; DNA, Mitochondrial; Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Subcutaneous Fat; Treatment Outcome; Young Adult; Zidovudine | 2012 |
Population-based sequencing of the V3-loop can predict the virological response to maraviroc in treatment-naive patients of the MERIT trial.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Cyclohexanes; Drug Combinations; Drug Therapy, Combination; Female; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Male; Maraviroc; Middle Aged; Polymerase Chain Reaction; Retrospective Studies; Sequence Analysis, DNA; Triazoles; Viral Load; Viral Tropism; Young Adult; Zidovudine | 2012 |
Anaemia in HIV-infected children: severity, types and effect on response to HAART.
Topics: Adolescent; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Cross-Sectional Studies; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Logistic Models; Male; Nevirapine; Prevalence; Prospective Studies; Severity of Illness Index; Treatment Outcome; Uganda; Zidovudine | 2012 |
Therapeutic levels of lopinavir in late pregnancy and abacavir passage into breast milk in the Mma Bana Study, Botswana.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Botswana; Breast Feeding; Dideoxynucleosides; Female; HIV Infections; HIV-1; Humans; Infant; Lactation; Lamivudine; Lopinavir; Middle Aged; Milk, Human; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine | 2013 |
A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine.
Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Diet; Drug Administration Schedule; Drug Substitution; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Peripheral Nervous System Diseases; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2012 |
Pharmacokinetic interactions between lersivirine and zidovudine, tenofovir disoproxil fumarate/emtricitabine and abacavir/lamivudine.
Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Interactions; Emtricitabine; Female; Healthy Volunteers; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nitriles; Organophosphonates; Pyrazoles; Tenofovir; Young Adult; Zidovudine | 2013 |
A randomized pahse I bioequivalence clinincal trial of a paediatric fixed-dose combination antiretroviral reconstitutable suspension in healthy adult volunteers.
Topics: Adult; Anti-HIV Agents; Cross-Over Studies; Drug Combinations; Female; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Therapeutic Equivalency; Young Adult; Zidovudine | 2013 |
Health outcomes of HIV-exposed uninfected African infants.
Topics: Anti-Retroviral Agents; Antiviral Agents; Breast Feeding; Cause of Death; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Infant; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Malawi; Morbidity; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Proportional Hazards Models; Zidovudine | 2013 |
A simplified combination antiretroviral therapy regimen enhances adherence, treatment satisfaction and quality of life: results of a randomized clinical trial.
Topics: Adult; Antiretroviral Therapy, Highly Active; Belgium; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Medication Adherence; Middle Aged; Netherlands; Odds Ratio; Patient Satisfaction; Quality of Life; Ritonavir; Zidovudine | 2014 |
High rate of HIV resuppression after viral failure on first-line antiretroviral therapy in the absence of switch to second-line therapy.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Nevirapine; Viral Load; Viremia; Zidovudine | 2014 |
Effectiveness of option B highly active antiretroviral therapy (HAART) prevention of mother-to-child transmission (PMTCT) in pregnant HIV women.
Topics: Administration, Oral; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Counseling; Drug Administration Schedule; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Infusions, Intravenous; Kenya; Lamivudine; Medication Adherence; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Socioeconomic Factors; Viral Load; Viremia; Young Adult; Zidovudine | 2014 |
High level of viral suppression and low switch rate to second-line antiretroviral therapy among HIV-infected adult patients followed over five years: retrospective analysis of the DART trial.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cross-Sectional Studies; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Probability; Retrospective Studies; RNA, Viral; Tenofovir; Uganda; Viral Load; Zidovudine | 2014 |
Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3 trial.
Topics: Anthropometry; Anti-HIV Agents; Child; Child, Preschool; Cross-Sectional Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lipid Metabolism; Lipodystrophy; Lipoproteins, HDL; Lipoproteins, LDL; Male; Nevirapine; Stavudine; Triglycerides; Viral Load; Zidovudine | 2014 |
Lipid levels and changes in body fat distribution in treatment-naive, HIV-1-Infected adults treated with rilpivirine or Efavirenz for 96 weeks in the ECHO and THRIVE trials.
Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Aged, 80 and over; Alkynes; Anti-HIV Agents; Benzoxazines; Body Fat Distribution; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Young Adult; Zidovudine | 2014 |
Relationship of vitamin D insufficiency to AIDS-associated Kaposi's sarcoma outcomes: retrospective analysis of a prospective clinical trial in Zimbabwe.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Dideoxynucleosides; Disease Progression; Female; Herpesvirus 8, Human; HIV-1; Humans; Lamivudine; Male; Middle Aged; Odds Ratio; Pilot Projects; Prospective Studies; RNA, Viral; Sarcoma, Kaposi; Survival Analysis; Treatment Outcome; Vitamin D; Vitamin D Deficiency; Zidovudine; Zimbabwe | 2014 |
First-line antiretroviral therapy with nevirapine versus lopinavir-ritonavir based regimens in a resource-limited setting.
Topics: Adenine; Adult; CD4 Lymphocyte Count; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2014 |
Efficacy and safety of darunavir/ritonavir at 48 weeks in treatment-naïve, HIV-1-infected adolescents: results from a phase 2 open-label trial (DIONE).
Topics: Adolescent; Anemia; CD4 Lymphocyte Count; Darunavir; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Nausea; Neutropenia; Reverse Transcriptase Inhibitors; Ritonavir; Sulfonamides; Time Factors; Viral Load; Vomiting; Zidovudine | 2014 |
Pre-antiretroviral therapy serum selenium concentrations predict WHO stages 3, 4 or death but not virologic failure post-antiretroviral therapy.
Topics: Adult; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Body Mass Index; C-Reactive Protein; CD4 Lymphocyte Count; Cyclopropanes; Deoxycytidine; Didanosine; Disease Progression; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Multivariate Analysis; Oligopeptides; Prospective Studies; Pyridines; Risk Factors; Selenium; World Health Organization; Zidovudine | 2014 |
A randomized controlled trial of single-class maintenance therapy with abacavir/lamivudine/zidovudine after standard triple antiretroviral induction therapy: final 96-week results from the FREE study.
Topics: Adult; Aged; Anti-HIV Agents; Belgium; CD4 Lymphocyte Count; Clinical Protocols; Dideoxynucleosides; Disease Progression; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lipids; Male; Middle Aged; Netherlands; Prospective Studies; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2015 |
Switching from zidovudine/lamivudine to tenofovir/emtricitabine improves fat distribution as measured by fat mass ratio.
Topics: Absorptiometry, Photon; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Fat Distribution; Drug Combinations; Drug Substitution; Emtricitabine; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Regression Analysis; Tenofovir; Zidovudine | 2015 |
In utero exposure to zidovudine and heart anomalies in the ANRS French perinatal cohort and the nested PRIMEVA randomized trial.
Topics: Adult; Anti-HIV Agents; Drug Combinations; Echocardiography; Female; Follow-Up Studies; France; Heart Defects, Congenital; Heart Septal Defects, Ventricular; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Sex Factors; Uterus; Young Adult; Zidovudine | 2015 |
Dual treatment with atazanavir-ritonavir plus lamivudine versus triple treatment with atazanavir-ritonavir plus two nucleos(t)ides in virologically stable patients with HIV-1 (SALT): 48 week results from a randomised, open-label, non-inferiority trial.
Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Deoxycytidine; Drug Substitution; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oligopeptides; Organophosphonates; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Viral Load; Zidovudine | 2015 |
Safety of zidovudine dose reduction in treatment-naïve HIV infected patients. A randomized controlled study (MiniZID).
Topics: Adult; Anemia; Anti-HIV Agents; Cameroon; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; Treatment Outcome; Zidovudine | 2016 |
Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial.
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Stavudine; Tablets; Uganda; Zambia; Zidovudine | 2016 |
Contribution of different antiretroviral regimens containing zidovudine, lamivudine and ritonavir-boosted lopinavir on HIV viral load reduction during pregnancy.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Ritonavir; Thailand; Viral Load; Zidovudine | 2016 |
In vitro-in vivo Pharmacokinetic correlation model for quality assurance of antiretroviral drugs.
Topics: Adolescent; Adult; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Caco-2 Cells; Humans; Lamivudine; Male; Models, Biological; Permeability; Rabbits; Solubility; Species Specificity; Stavudine; Young Adult; Zidovudine | 2015 |
Bleeding patterns of HIV-infected women using an etonogestrel-releasing contraceptive implant and efavirenz-based or lopinavir/ritonavir-based antiretroviral therapy.
Topics: Adolescent; Adult; Alkynes; Amenorrhea; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Desogestrel; Drug Combinations; Drug Implants; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Metrorrhagia; Prospective Studies; Ritonavir; Young Adult; Zidovudine | 2016 |
Efficacy and safety of tenofovir-containing antiretroviral therapy in women who acquired HIV while enrolled in tenofovir gel prophylaxis trials.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Emtricitabine; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Patient Safety; Pregnancy; Primary Prevention; RNA, Viral; South Africa; Tenofovir; Treatment Outcome; Vaginal Creams, Foams, and Jellies; Viral Load; Zidovudine | 2017 |
A randomized two-way crossover bioequivalence study in healthy adult volunteers of paediatric zidovudine/lamivudine/nevirapine fast-disintegrating fixed-dose combination tablet.
Topics: Adult; Cross-Over Studies; Drug Combinations; Female; Healthy Volunteers; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Solubility; Tablets; Therapeutic Equivalency; Young Adult; Zidovudine | 2017 |
Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060.
Topics: Antimalarials; CD4 Lymphocyte Count; Child; Child, Preschool; Coinfection; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Malaria, Falciparum; Malawi; Male; Nevirapine; Plasmodium falciparum; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine | 2016 |
Insulin-Like Growth Factor Is Associated with Changes in Body Composition with Antiretroviral Therapy Initiation.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Body Composition; Cyclopropanes; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Insulin-Like Growth Factor I; Lamivudine; Male; Prospective Studies; Tenofovir; Zidovudine | 2017 |
Assessment of Nevirapine Prophylactic and Therapeutic Dosing Regimens for Neonates.
Topics: Anti-HIV Agents; Breast Feeding; Chemoprevention; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Thailand; World Health Organization; Zidovudine | 2017 |
Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Biological Variation, Population; Child; Child, Preschool; Cyclopropanes; Drug Monitoring; Female; HIV Infections; Humans; Lamivudine; Male; Tanzania; Zidovudine | 2018 |
Association between HIV antiretroviral therapy and preterm birth based on antenatal ultrasound gestational age determination: a comparative analysis.
Topics: Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Emtricitabine; Female; Gestational Age; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Lopinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Premature Birth; Risk; Ritonavir; Tenofovir; Ultrasonography, Prenatal; Young Adult; Zidovudine | 2019 |
Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Integrase Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Outcome Assessment, Health Care; Pregnancy; Pregnancy Complications, Infectious; Raltegravir Potassium; Viral Load; Young Adult; Zidovudine | 2020 |
Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092.
Topics: Africa South of the Sahara; Anti-HIV Agents; Area Under Curve; Child, Preschool; Chromatography, Liquid; Cohort Studies; Drug Combinations; Drug Elimination Routes; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Lopinavir; Male; Patient Safety; Ritonavir; Severe Acute Malnutrition; Tandem Mass Spectrometry; Zidovudine | 2021 |
Brief Report: Vaginal Viral Shedding With Undetectable Plasma HIV Viral Load in Pregnant Women Receiving 2 Different Antiretroviral Regimens: A Randomized Clinical Trial.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Raltegravir Potassium; Vigna; Viral Load; Virus Shedding; Zidovudine | 2021 |
Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial, randomised, non
Topics: Anti-HIV Agents; Darunavir; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-1; Humans; Lamivudine; Oxazines; Piperazines; Prospective Studies; Pyridones; Ritonavir; RNA; Tenofovir; Viral Load; Zidovudine | 2022 |
Brief Report: Impact of Antiretroviral Regimen on Pregnancy and Infant Outcomes in Women With HIV/ HBV Coinfection.
Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Coinfection; Emtricitabine; Female; Hepatitis B e Antigens; HIV Infections; Humans; Infant, Newborn; Lamivudine; Pregnancy; Pregnancy Outcome; Tenofovir; Zidovudine | 2022 |
1029 other study(ies) available for lamivudine and zidovudine
Article | Year |
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Structure-activity relationships of beta-D-(2S,5R)- and alpha-D-(2S,5S)-1,3-oxathiolanyl nucleosides as potential anti-HIV agents.
Topics: Antiviral Agents; Cytosine; HIV-1; Humans; Hypoxanthines; Leukocytes, Mononuclear; Molecular Conformation; Molecular Structure; Purines; Structure-Activity Relationship; Uracil | 1993 |
Asymmetric synthesis and biological evaluation of beta-L-(2R,5S)- and alpha-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents.
Topics: Antiviral Agents; Blood; Cells, Cultured; Heterocyclic Compounds; HIV-1; Humans; Magnetic Resonance Spectroscopy; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Thiophenes | 1993 |
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs.
Topics: Acyclovir; Animals; Anion Transport Proteins; Antiviral Agents; Carrier Proteins; Didanosine; In Vitro Techniques; Lamivudine; Oocytes; Rats; Stavudine; Transfection; Trifluridine; Xenopus laevis; Zalcitabine; Zidovudine | 2000 |
Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp.
Topics: Animals; Antimalarials; Bromobenzenes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dioxanes; Gas Chromatography-Mass Spectrometry; Hepatitis B; HIV; Humans; Jamaica; Lactones; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Mycobacterium tuberculosis; Neoplasms, Unknown Primary; Nuclear Magnetic Resonance, Biomolecular; Plasmodium berghei; Plasmodium falciparum; Porifera; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured | 2001 |
The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1).
Topics: Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Etoposide; Flow Cytometry; HIV Protease Inhibitors; Humans; Multidrug Resistance-Associated Proteins; Probenecid; Reverse Transcriptase Inhibitors; Ritonavir; Tumor Cells, Cultured | 2002 |
Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.
Topics: Animals; Anti-HIV Agents; Antiviral Agents; Binding Sites; Cell Line; Chlorocebus aethiops; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Models, Molecular; Mutation; Purine Nucleosides; Pyrimidine Nucleosides; Quantum Theory; Stereoisomerism; Zalcitabine | 2002 |
Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; CD4-Positive T-Lymphocytes; Cells, Cultured; Doxorubicin; Drug Resistance, Neoplasm; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Lamivudine; Microbial Sensitivity Tests; Neoplasm Proteins; Reverse Transcriptase Inhibitors; Zidovudine | 2003 |
l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.
Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Resistance, Viral; Drug Stability; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Lamivudine; Leukocytes, Mononuclear; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleosides; Point Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2003 |
Synthesis, structure-activity relationships, and mechanism of drug resistance of D- and L-beta-3'-fluoro-2',3'-unsaturated-4'-thionucleosides as anti-HIV agents.
Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Mutation; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Thionucleosides | 2004 |
Synthesis, structure-activity relationships, and drug resistance of beta-d-3'-fluoro-2',3'-unsaturated nucleosides as anti-HIV Agents.
Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Stability; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Nucleosides; Structure-Activity Relationship | 2004 |
(Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a new class of methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
Topics: Adenosine Deaminase; Antiviral Agents; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 4, Human; Nucleosides; Virus Replication | 2004 |
Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
Topics: Adenine; Anti-HIV Agents; Cells, Cultured; Cyclopentanes; Dideoxynucleosides; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Lamivudine; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Mutation; Stereoisomerism; Structure-Activity Relationship | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
Topics: Adenine; Adenosine Deaminase; Antiviral Agents; Cyclopropanes; Cytomegalovirus; Cytopathogenic Effect, Viral; Guanine; Hepatitis B virus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV-1; Humans; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Viral Plaque Assay | 2006 |
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.
Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Catalysis; Cell Line; Dose-Response Relationship, Drug; Endogenous Retroviruses; HIV-1; Humans; Kidney; Molecular Sequence Data; Organophosphonates; Polymerase Chain Reaction; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Stavudine; Swine; Swine, Miniature; Tenofovir; Virus Replication; Zidovudine | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase.
Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine | 2007 |
Human immunodeficiency virus types 1 and 2 exhibit comparable sensitivities to Zidovudine and other nucleoside analog inhibitors in vitro.
Topics: Anti-HIV Agents; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Zidovudine | 2008 |
Anti-BK virus activity of nucleoside analogs.
Topics: Adenine; BK Virus; Esters; Fatty Acids; Humans; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Virus Replication | 2008 |
Entecavir exhibits inhibitory activity against human immunodeficiency virus under conditions of reduced viral challenge.
Topics: Antiviral Agents; Cell Line; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans | 2008 |
Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus.
Topics: Alkaloids; Anti-HIV Agents; Antiviral Agents; Crystallography, X-Ray; Drugs, Chinese Herbal; Hepatitis B virus; HIV-1; Humans; Inhibitory Concentration 50; Menispermaceae; Molecular Conformation; Molecular Structure; Plants, Medicinal | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells.
Topics: Cell Proliferation; Cells, Cultured; Dideoxynucleosides; DNA, Mitochondrial; Humans; Lamivudine; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Nucleosides; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Mitochondrial; Stavudine; Zidovudine | 2008 |
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship | 2009 |
Human immunodeficiency virus type 1 isolates with the reverse transcriptase (RT) mutation Q145M retain nucleoside and nonnucleoside RT inhibitor susceptibility.
Topics: Amino Acid Sequence; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors | 2009 |
Genital tract, cord blood, and amniotic fluid exposures of seven antiretroviral drugs during and after pregnancy in human immunodeficiency virus type 1-infected women.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amniotic Fluid; Anti-HIV Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Fetal Blood; Genitalia, Female; HIV-1; Humans; Hydrocortisone; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors | 2009 |
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.
Topics: Anti-HIV Agents; Computer Simulation; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; Stavudine | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.
Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Macrophages; Nucleosides; Nucleotides; Organophosphonates; Tenofovir | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Antiviral activity of seed extract from Citrus bergamia towards human retroviruses.
Topics: Benzoxepins; Citrus; HIV Reverse Transcriptase; HIV-1; Humans; Limonins; Reverse Transcriptase Inhibitors; Seeds | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides.
Topics: Antiviral Agents; Cell Line; Glycosylation; Hepatitis B virus; HIV-1; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Models, Molecular; Nucleosides; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization | 2011 |
Library-based discovery and characterization of daphnane diterpenes as potent and selective HIV inhibitors in Daphne gnidium.
Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Daphne; Diterpenes; Heterocyclic Compounds, 4 or More Rings; Mediterranean Region; Molecular Structure; Receptors, CXCR4 | 2012 |
Synthesis and anti-HIV activities of glutamate and peptide conjugates of nucleoside reverse transcriptase inhibitors.
Topics: Acetates; Anti-HIV Agents; Cell Line; Drug Resistance, Multiple, Viral; Esters; Glutamates; HIV-1; Humans; Myristic Acids; Nucleosides; Oligopeptides; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2012 |
Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Cell Line; Dicarboxylic Acids; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2012 |
2'-Fluoro-6'-methylene-carbocyclic adenosine phosphoramidate (FMCAP) prodrug: in vitro anti-HBV activity against the lamivudine-entecavir resistant triple mutant and its mechanism of action.
Topics: Adenosine; Antiviral Agents; Binding Sites; Cells, Cultured; Drug Resistance, Viral; Guanine; Hepatitis B virus; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Lamivudine; Models, Molecular; Molecular Structure; Mutation; Prodrugs; Thermodynamics | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
Topics: Anti-HIV Agents; Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Prodrugs; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of CHX-DAPYs as HIV-1 non-nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Benzamides; Cell Survival; Cells, Cultured; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication | 2014 |
Jatrophane diterpenes as inhibitors of chikungunya virus replication: structure-activity relationship and discovery of a potent lead.
Topics: Alphavirus Infections; Antiviral Agents; Chikungunya Fever; Chikungunya virus; Diterpenes; Euphorbia; France; HIV-1; HIV-2; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Semliki forest virus; Sindbis Virus; Structure-Activity Relationship; Virus Replication | 2014 |
Design and synthesis of a new series of modified CH-diarylpyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2014 |
Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization.
Topics: Anti-HIV Agents; Catalytic Domain; Dose-Response Relationship, Drug; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Niacinamide; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured | 2014 |
Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2015 |
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.
Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Nitrogen; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Sulfones | 2015 |
Design, synthesis of new β-carboline derivatives and their selective anti-HIV-2 activity.
Topics: Carbolines; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Piperazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2015 |
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines.
Topics: Anti-HIV Agents; Chemistry Techniques, Synthetic; Computational Biology; Drug Design; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Docking Simulation; Protein Conformation; Pyrazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2015 |
Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata.
Topics: Antiviral Agents; Chikungunya virus; Diterpenes; Euphorbiaceae; France; HCT116 Cells; HIV-1; HIV-2; Humans; Macrocyclic Compounds; MCF-7 Cells; Molecular Structure; Semliki forest virus; Sindbis Virus; Virus Replication | 2015 |
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
Topics: Acyclovir; Animals; Antiviral Agents; Betulinic Acid; Chlorocebus aethiops; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Vero Cells; Virus Replication | 2015 |
Characterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNA.
Topics: Anti-HIV Agents; Boronic Acids; HeLa Cells; HIV Core Protein p24; HIV-1; Humans; Integrase Inhibitors; Lamivudine; Nucleic Acid Conformation; Peptide Library; Peptides; Quinolones; Raltegravir Potassium; Response Elements; RNA, Viral; Structure-Activity Relationship; Virus Replication; Zidovudine | 2016 |
Design, synthesis and anti-HIV activity of novel quinoxaline derivatives.
Topics: Animals; Anti-HIV Agents; Chlorocebus aethiops; Computer Simulation; Drug Design; HIV Integrase; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Quinoxalines; Vero Cells | 2016 |
Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket.
Topics: Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; Molecular Docking Simulation; Protein Conformation; Pyridines; Pyrimidines; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Water | 2016 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles.
Topics: Animals; Anti-HIV Agents; Cell Line, Tumor; Drug Resistance, Viral; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Molecular Docking Simulation; Mutation; Pyrimidines; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfonamides; Thiophenes | 2016 |
Synthesis and anti-HIV activities of unsymmetrical long chain dicarboxylate esters of dinucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Dicarboxylic Acids; Esters; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nucleosides; Reverse Transcriptase Inhibitors | 2017 |
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship | 2017 |
Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities.
Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV; HIV Reverse Transcriptase; Humans; Indazoles; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2020 |
Targeting dual tolerant regions of binding pocket: Discovery of novel morpholine-substituted diarylpyrimidines as potent HIV-1 NNRTIs with significantly improved water solubility.
Topics: Binding Sites; HIV Reverse Transcriptase; HIV-1; Morpholines; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Water | 2020 |
Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp
Topics: Anti-HIV Agents; Binding Sites; Drug Design; HIV-1; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2021 |
Design of the naphthyl-diarylpyrimidines as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) via structure-based extension into the entrance channel.
Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Naphthalenes; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
Topics: Antiviral Agents; Emtricitabine; HIV; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine; Zidovudine | 1992 |
Cellular metabolism of (-) enantiomeric 2'-deoxy-3'-thiacytidine.
Topics: Acquired Immunodeficiency Syndrome; Blood Platelets; Cells, Cultured; Humans; Lamivudine; Lymphocytes; Pentosyltransferases; Phosphorylation; Pyrimidine Phosphorylases; Stereoisomerism; Thymidine Phosphorylase; Zalcitabine; Zidovudine | 1992 |
Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.
Topics: Antiviral Agents; HIV-1; Humans; Lamivudine; Lymphocytes; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship; Zalcitabine; Zidovudine | 1992 |
(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro.
Topics: Cell Death; Cells, Cultured; Didanosine; Giant Cells; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; RNA-Directed DNA Polymerase; Tritium; Virus Replication; Zalcitabine; Zidovudine | 1992 |
Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytosine; Drug Resistance, Microbial; HIV-1; Humans; Lamivudine; Nucleosides; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine | 1991 |
Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog.
Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cytosine; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Monocytes; T-Lymphocytes; Virus Replication; Zidovudine | 1991 |
HIV-1, the brain, and combination therapy.
Topics: Adult; AIDS Dementia Complex; Antiviral Agents; Child; Didanosine; Drug Combinations; HIV-1; Humans; Lamivudine; Neuroprotective Agents; Stavudine; Zalcitabine; Zidovudine | 1995 |
A quarter-century of antiviral therapy.
Topics: Antiviral Agents; Drug Therapy, Combination; Hepatitis B; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Zalcitabine; Zidovudine | 1995 |
[AIDS therapy with reverse transcriptase inhibitors].
Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 1993 |
Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Codon; Didanosine; DNA Primers; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine | 1994 |
Comparison of cord blood and peripheral blood mononuclear cells as targets for viral isolation and drug sensitivity studies involving human immunodeficiency virus type 1.
Topics: Antiviral Agents; Dose-Response Relationship, Drug; Fetal Blood; HIV Core Protein p24; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Microbial Sensitivity Tests; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine | 1994 |
Fighting all the time.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine | 1995 |
In vitro comparison of selected triple-drug combinations for suppression of HIV-1 replication: the Inter-Company Collaboration Protocol.
Topics: Antiviral Agents; Cell Line, Transformed; Cytopathogenic Effect, Viral; Didanosine; Drug Synergism; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nevirapine; Pyridines; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; Virus Replication; Zalcitabine; Zidovudine | 1995 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine | 1995 |
Possible involvement of cell fusion and viral recombination in generation of human immunodeficiency virus variants that display dual resistance to AZT and 3TC.
Topics: Antiviral Agents; Base Sequence; Cell Fusion; Cell Line; Coculture Techniques; DNA Mutational Analysis; Drug Resistance, Multiple; Genes, pol; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; Recombination, Genetic; T-Lymphocytes; Virus Cultivation; Zalcitabine; Zidovudine | 1995 |
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.
Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Conserved Sequence; Deoxycytidine; Drug Resistance, Microbial; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Structure-Activity Relationship; T-Lymphocytes; Thionucleosides; Zalcitabine; Zidovudine | 1993 |
AIDS mood upbeat--for a change.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Gene Products, nef; Herpesviridae; HIV; Humans; Lamivudine; nef Gene Products, Human Immunodeficiency Virus; Sarcoma, Kaposi; Simian Immunodeficiency Virus; Virus Replication; Zalcitabine; Zidovudine | 1995 |
In vitro immunotoxicity of +/- 2'-deoxy-3'-thiacytidine, a new anti-HIV agent.
Topics: Antiviral Agents; B-Lymphocytes; CD3 Complex; Cytokines; Female; HIV Infections; HIV-1; Humans; Immunoglobulins; Lamivudine; Lymphocyte Activation; Male; Phytohemagglutinins; T-Lymphocytes; Zalcitabine; Zidovudine | 1993 |
Effect of 3'-azido-3'-deoxythymidine on human immunodeficiency virus type 1 replication in human fetal brain macrophages.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Brain; Cells, Cultured; DNA, Viral; Fetus; HIV Core Protein p24; HIV-1; Humans; Lamivudine; Macrophages; RNA, Messenger; Stereoisomerism; Time Factors; Virus Replication; Zalcitabine; Zidovudine | 1993 |
Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNA.
Topics: Antiviral Agents; Base Sequence; Cells, Cultured; Didanosine; Dideoxynucleotides; DNA, Viral; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosides; Nucleotides; Phytohemagglutinins; RNA, Viral; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine | 1996 |
Inhibitory effect of 3'-azido-3'-deoxythymidine on proliferative responsiveness of CD8+ lymphocytes to interleukin-2.
Topics: Antiviral Agents; CD8-Positive T-Lymphocytes; Cell Division; Didanosine; Humans; Interleukin-2; Lamivudine; Lymphocyte Activation; Zalcitabine; Zidovudine | 1994 |
A new HIV/AIDS drug.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Zalcitabine; Zidovudine | 1996 |
Increased zidovudine prescribing associated with lamivudine availability.
Topics: Antiviral Agents; British Columbia; Drug Utilization; Humans; Lamivudine; Zalcitabine; Zidovudine | 1996 |
Lamivudine as adjunct therapy in HIV.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zalcitabine; Zidovudine | 1996 |
New nucleoside analogue, lamivudine, released for HIV therapy.
Topics: Antiviral Agents; Drug Therapy, Combination; HIV Infections; Lamivudine; Zalcitabine; Zidovudine | 1996 |
New guidelines set for occupational HIV exposure.
Topics: Accidents, Occupational; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Practice Guidelines as Topic; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1996 |
Human immunodeficiency virus type 1 kinetics in lymph nodes compared with plasma.
Topics: Antiviral Agents; Biopsy; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Kinetics; Lamivudine; Lymph Nodes; RNA, Viral; Viremia; Zalcitabine; Zidovudine | 1996 |
HIV's Achilles' heel. Drugs and education are starting to slow the AIDS virus.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Health Education; Humans; Indinavir; Lamivudine; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 1996 |
Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility.
Topics: Antiviral Agents; Codon; Drug Therapy, Combination; Genetic Variation; HeLa Cells; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zalcitabine; Zidovudine | 1996 |
Interaction between lamivudine (3TC) and other nucleoside analogues for intracellular phosphorylation.
Topics: Antiviral Agents; Humans; Lamivudine; Phosphorylation; Zalcitabine; Zidovudine | 1996 |
Kinetics of viral clearance in plasma, peripheral blood mononuclear cells and lymph nodes.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymph Nodes; Male; Plasma; RNA, Viral; Time Factors; Zidovudine | 1996 |
New combinations of drug therapies for the treatment of the human immunodeficiency virus (HIV)
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Protease Inhibitors; Time Factors; Zidovudine | 1996 |
An update on HIV/AIDS.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; United States; Viremia; Zidovudine | 1996 |
Lamivudine-zidovudine treatment and clinical end points.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine | 1996 |
Selection in vitro of an HIV-1 variant resistant to both lamivudine (3TC) and zidovudine.
Topics: Drug Resistance, Microbial; Genetic Variation; HIV-1; Lamivudine; Zidovudine | 1996 |
[Lamivudine-zidovudine combination treatment].
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine | 1996 |
Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model.
Topics: Drug Resistance, Microbial; Genetic Variation; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mathematical Computing; Models, Biological; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
[HIV: less resistance due to combined treatment].
Topics: Adult; Anti-HIV Agents; Computer Graphics; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Time Factors; Zidovudine | 1996 |
[HIV: to administer protease inhibitors early].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Time Factors; Zalcitabine; Zidovudine | 1996 |
Reverse transcriptase fidelity and HIV-1 variation.
Topics: Anti-HIV Agents; Cells, Cultured; Drug Resistance, Microbial; Drug Therapy, Combination; Genetic Variation; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
HIV postexposure prophylaxis: new recommendations.
Topics: Anti-HIV Agents; Blood-Borne Pathogens; Chemoprevention; Drug Combinations; Guidelines as Topic; Health Personnel; HIV Infections; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Diseases; Zidovudine | 1997 |
Increased activation of the combination of 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine in the presence of hydroxyurea.
Topics: Anti-HIV Agents; Cell Line; Deoxycytosine Nucleotides; Drug Synergism; Hydroxyurea; Lamivudine; Phosphorylation; Thymine Nucleotides; Zidovudine | 1997 |
Correspondence between the effect of zidovudine plus lamivudine on plasma HIV level/CD4 lymphocyte count and the incidence of clinical disease in infected individuals. North American Lamivudine HIV Working Group.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 1997 |
Focusing on the second phase of plasma HIV-1 RNA clearance.
Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Virus Replication; Zidovudine | 1997 |
Saquinavir interaction with midazolam: pharmacokinetic considerations when prescribing protease inhibitors for patients with HIV disease.
Topics: Adult; Anti-HIV Agents; Cytochrome P-450 Enzyme System; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Hypnotics and Sedatives; Lamivudine; Liver; Male; Midazolam; Saquinavir; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine | 1997 |
The art of 'HAART': researchers probe the potential and limits of aggressive HIV treatments.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
Effect of antiretroviral combination therapy (zidovudine/didanosine or zidovudine/lamivudine) on quantitative plasma human immunodeficiency virus-ribonucleic acid in children and adolescents infected with human immunodeficiency virus.
Topics: Adolescent; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; RNA, Viral; Time Factors; Viral Load; Viremia; Zidovudine | 1997 |
Human immunodeficiency virus drug therapy and virus load.
Topics: Anti-HIV Agents; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 1997 |
[Antiretroviral drugs in the primary and secondary prevention of HIV infection].
Topics: Antiviral Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Zidovudine | 1997 |
The maternal-fetal transfer of lamivudine in the ex vivo human placenta.
Topics: Anti-HIV Agents; Female; Humans; Lamivudine; Maternal-Fetal Exchange; Pregnancy; Zidovudine | 1997 |
Investigators study morning-after AIDS treatment.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Coitus; Contraceptives, Postcoital; Female; Health Knowledge, Attitudes, Practice; HIV-1; Humans; Lamivudine; Zidovudine | 1997 |
Three-drug combination of MKC-442, lamivudine and zidovudine in vitro: potential approach towards effective chemotherapy against HIV-1.
Topics: Anti-HIV Agents; Cell Line, Transformed; Cells, Cultured; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Uracil; Zidovudine | 1997 |
In vitro screening of nucleoside analog combinations for potential use in anti-HIV therapy.
Topics: Anti-HIV Agents; Biotransformation; Drug Evaluation, Preclinical; Drug Interactions; Humans; Lamivudine; Phosphorylation; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 1997 |
HIV trial stopped early after good results.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Zidovudine | 1997 |
Treatment options for human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Drug Approval; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Lamivudine; Male; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
Genotypic and phenotypic changes during culture of a multinucleoside-resistant human immunodeficiency virus type 1 strain in the presence and absence of additional reverse transcriptase inhibitors.
Topics: Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; Drug Interactions; Drug Resistance, Microbial; Drug Resistance, Multiple; Genotype; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine | 1996 |
Decay characteristics of HIV-1-infected compartments during combination therapy.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; Half-Life; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Isoquinolines; Lamivudine; Leukocytes, Mononuclear; Macrophages; Mathematics; Models, Biological; Nelfinavir; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Sulfonic Acids; Viral Load; Viremia; Virus Latency; Zidovudine | 1997 |
Response of HIV-associated thrombocytopenia to triple agent antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Saquinavir; Thrombocytopenia; Zalcitabine; Zidovudine | 1997 |
New drugs--reports of new drugs recently approved by the FDA. Lamivudine.
Topics: Administration, Oral; Anti-HIV Agents; Area Under Curve; Biological Availability; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 1997 |
Sequence and drug susceptibility of subtype C reverse transcriptase from human immunodeficiency virus type 1 seroconverters in Zimbabwe.
Topics: Adult; Amino Acid Sequence; Base Sequence; Didanosine; DNA, Viral; Female; Genes, env; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Nevirapine; Nucleic Acid Heteroduplexes; Phylogeny; Pyridines; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Zidovudine; Zimbabwe | 1997 |
Quantification of HIV-1 viral load in lymphoid and blood cells: assessment during four-drug combination therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymph Nodes; Male; Polymerase Chain Reaction; RNA, Viral; Saquinavir; Viral Load; Viremia; Zidovudine | 1997 |
Increased fidelity of drug-selected M184V mutated HIV-1 reverse transcriptase as the basis for the effectiveness of 3TC in HIV clinical trials.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Microbial; Female; Genes, env; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Point Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 1997 |
Cross-resistance analysis and molecular modeling of nonnucleoside reverse transcriptase inhibitors targeting drug-resistance mutations in the reverse transcriptase of human immunodeficiency virus.
Topics: Drug Resistance, Microbial; Genetic Variation; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Models, Molecular; Molecular Conformation; Point Mutation; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine | 1997 |
A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml.
Topics: Adenosine; Anti-HIV Agents; Cytidine; DNA; DNA, Viral; Drug Therapy, Combination; Guanosine; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Nelfinavir; Nucleic Acid Hybridization; RNA, Viral; Sulfonic Acids; Zidovudine | 1997 |
Downregulation of increased CD95 (APO-1/Fas) ligand in T cells from human immunodeficiency virus-type 1-infected children after antiretroviral therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Therapy, Combination; Fas Ligand Protein; fas Receptor; Gene Expression Regulation; HIV Infections; HIV-1; Humans; Lamivudine; Membrane Glycoproteins; Reverse Transcriptase Inhibitors; RNA, Messenger; T-Lymphocytes; Time Factors; Transcription, Genetic; Zalcitabine; Zidovudine | 1997 |
Lamivudine-resistant human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-resistant to zidovudine in vivo.
Topics: Amino Acid Sequence; Anti-HIV Agents; CD4 Lymphocyte Count; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; RNA, Viral; Zidovudine | 1997 |
Cure or control of HIV/AIDS?
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Kinetics; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
Central nervous system as a sanctuary for HIV-1 infection despite treatment with zidovudine, lamivudine and indinavir.
Topics: Anti-HIV Agents; Central Nervous System; Dideoxynucleosides; Drug Therapy, Combination; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
Postexposure chemoprophylaxis for occupational exposure to HIV in the dental office.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-HIV Agents; Chemoprevention; Child; Dental Auxiliaries; Dentists; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Diseases; Occupational Exposure; Practice Guidelines as Topic; Risk Factors; United States; United States Public Health Service; Universal Precautions; Zidovudine | 1997 |
Human immunodeficiency virus type 1 dynamics in different lymphoid tissue compartments.
Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphoid Tissue; Male; RNA, Viral; Zidovudine | 1997 |
In vitro effects of continuous pressure with zidovudine (ZDV) and lamivudine on a ZDV-resistant HIV-1 isolate.
Topics: Anti-HIV Agents; Cells, Cultured; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Core Protein p24; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Phytohemagglutinins; Tumor Cells, Cultured; Zidovudine | 1997 |
[The management of the occupational exposures of health workers to HIV].
Topics: Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Health Personnel; HIV Infections; HIV-1; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Exposure; Saquinavir; Zidovudine | 1997 |
Lamivudine (3TC) phosphorylation and drug interactions in vitro.
Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Interactions; Humans; Kinetics; Lamivudine; Lymphocyte Activation; Lymphocytes; Mitogens; Models, Chemical; Monocytes; Phosphorylation; Stavudine; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 1997 |
Protease inhibitor therapy in children with perinatally acquired HIV infection.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Protease Inhibitors; Retrospective Studies; Ritonavir; Saquinavir; Stavudine; Zidovudine | 1997 |
The good news about AIDS.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Humans; Lamivudine; Models, Theoretical; Protease Inhibitors; Time Factors; Zidovudine | 1997 |
Zidovudine-resistant human immunodeficiency virus type 1 strains subcultured in the presence of both lamivudine and quinoxaline HBY 097 retain marked sensitivity to HBY 097 but not to lamivudine.
Topics: Anti-HIV Agents; Antiviral Agents; Cells, Cultured; Drug Resistance; HIV-1; Humans; Lamivudine; Mutation; Quinoxalines; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Coculture Techniques; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Lymphocyte Activation; Mutation; RNA, Viral; T-Lymphocyte Subsets; Viral Load; Viremia; Virus Activation; Virus Latency; Virus Replication; Zidovudine | 1997 |
Two-in-one tablet eases 'pill burden'.
Topics: Anti-HIV Agents; Drug Combinations; HIV Seropositivity; Humans; Lamivudine; Zidovudine | 1997 |
[HIV-therapy: as early and as intensive as possible].
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Treatment Outcome; Zidovudine | 1997 |
Complete regression of giant molluscum contagiosum lesions in an HIV-infected patient following combined antiretroviral therapy with saquinavir, zidovudine and lamivudine.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination; Humans; Lamivudine; Male; Molluscum Contagiosum; Saquinavir; Zidovudine | 1997 |
First combination drug for patients with HIV.
Topics: Anti-HIV Agents; Drug Combinations; HIV Infections; Humans; Lamivudine; Zidovudine | 1997 |
Drugs for HIV infection.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Delavirdine; Diarrhea; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Virus Replication; Zalcitabine; Zidovudine | 1997 |
Sho-saiko-to, a traditional Kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; HIV Core Protein p24; HIV-1; Humans; Lamivudine; Monocytes; Virus Replication; Zidovudine | 1997 |
Indinavir urinary stones as origin of upper urinary tract obstruction.
Topics: Aged; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Ureteral Calculi; Ureteral Obstruction; Zidovudine | 1997 |
HIV-1 RNA detectable with ultrasensitive quantitative polymerase chain reaction in plasma but not in cerebrospinal fluid during combination treatment with zidovudine, lamivudine and indinavir.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Monitoring; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Polymerase Chain Reaction; RNA, Viral; Zidovudine | 1998 |
Drug susceptibility of subtypes A,B,C,D, and E human immunodeficiency virus type 1 primary isolates.
Topics: Anti-HIV Agents; Cell Line, Transformed; Cells, Cultured; Didanosine; Foscarnet; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Zidovudine | 1998 |
thy/liv-SCID-hu mice: a system for investigating the in vivo effects of multidrug therapy on plasma viremia and human immunodeficiency virus replication in lymphoid tissues.
Topics: Animals; Anti-HIV Agents; Chronic Disease; Drug Resistance, Microbial; Drug Therapy, Combination; Fetal Tissue Transplantation; Flow Cytometry; HIV Infections; HIV-1; Lamivudine; Leukocytes, Mononuclear; Liver Transplantation; Mice; Mice, SCID; Recurrence; Ritonavir; RNA, Viral; Saquinavir; Thymus Gland; Viremia; Zidovudine | 1998 |
Oligonucleotide ligation assay for detecting mutations in the human immunodeficiency virus type 1 pol gene that are associated with resistance to zidovudine, didanosine, and lamivudine.
Topics: Anti-HIV Agents; Codon; Didanosine; Drug Resistance, Microbial; Genes, pol; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; RNA, Viral; Sensitivity and Specificity; Sequence Analysis, DNA; Zidovudine | 1998 |
Paediatric AIDS--is now not the right time to act?
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 1997 |
Effect of protease inhibitors on nucleoside analogue phosphorylation in vitro.
Topics: Anti-HIV Agents; Cell Count; Cell Survival; Didanosine; Drug Interactions; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Phosphorylation; Protease Inhibitors; Ritonavir; Saquinavir; Stavudine; Trypan Blue; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 1998 |
Neurodevelopmental/neuroradiologic recovery of a child infected with HIV after treatment with combination antiretroviral therapy using the HIV-specific protease inhibitor ritonavir.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Brain; CD4 Lymphocyte Count; Child; Cognition Disorders; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Magnetic Resonance Imaging; Male; Psychological Tests; Ritonavir; Virus Replication; Zidovudine | 1998 |
Survival in 2367 zidovudine-treated patients according to use of other nucleoside analogue drugs. The EuroSIDA Study Group.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Dideoxynucleosides; Disease Progression; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Stavudine; Survival Analysis; Zalcitabine; Zidovudine | 1998 |
A novel point mutation at position 156 of reverse transcriptase from feline immunodeficiency virus confers resistance to the combination of (-)-beta-2',3'-dideoxy-3'-thiacytidine and 3'-azido-3'-deoxythymidine.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cats; Cell Line; Drug Interactions; Drug Resistance, Microbial; Immunodeficiency Virus, Feline; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Serine; Viral Plaque Assay; Zidovudine | 1998 |
[Chronic HIV- and chronic HBV infection with hematuria and proteinuria].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Chronic Disease; Environmental Monitoring; Erythrocyte Count; Hazardous Substances; Hematuria; Hepatitis B; HIV-1; Humans; Lamivudine; Male; Occupational Exposure; Proteinuria; Zidovudine | 1998 |
Retention of marked sensitivity to (S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3,4-di hydroquin oxaline-2(1H)-thione (HBY 097) by an azidothymidine (AZT)-resistant human immunodeficiency virus type 1 (HIV-1) strain subcultured in the combined
Topics: Anti-HIV Agents; Antiviral Agents; Benzodiazepines; Cell Line; Delavirdine; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Lamivudine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mutation; Nevirapine; Quinoxalines; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zidovudine | 1998 |
Glaxo cuts HIV drug cost for developing world.
Topics: Anti-HIV Agents; Costs and Cost Analysis; Developing Countries; Drug Industry; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Zidovudine | 1998 |
Profound and unanticipated anemia with lamivudine-zidovudine combination therapy in zidovudine-experienced patients with HIV infection.
Topics: Adult; Anemia; Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Zidovudine | 1998 |
Regression of cytomegalovirus retinitis associated with protease-inhibitor treatment in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Saquinavir; Stavudine; Zidovudine | 1998 |
[Hepatic steatosis during treatment with zidovudine and lamivudine in an HIV-positive patient].
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Fatty Liver; HIV Seropositivity; Humans; Lamivudine; Male; Transaminases; Zidovudine | 1998 |
Early intervention to block HIV.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Zidovudine | 1998 |
Drug shows potency against HIV.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Zidovudine | 1996 |
A novel polymorphism at codon 333 of human immunodeficiency virus type 1 reverse transcriptase can facilitate dual resistance to zidovudine and L-2',3'-dideoxy-3'-thiacytidine.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Polymorphism, Genetic; Zidovudine | 1998 |
Changes in CD4+ and CD8+ T cell subsets in response to highly active antiretroviral therapy in HIV type 1-infected patients with prior protease inhibitor experience.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Lymphocyte Activation; Lymphocyte Count; Middle Aged; Prospective Studies; Receptors, Antigen, T-Cell, alpha-beta; RNA, Viral; T-Lymphocyte Subsets; Viral Load; Zidovudine | 1998 |
Low blood-brain barrier permeability to azidothymidine (AZT), 3TC, and thymidine in the rat.
Topics: Animals; Anti-HIV Agents; Blood-Brain Barrier; Drug Evaluation, Preclinical; Lamivudine; Male; Rats; Rats, Sprague-Dawley; Thymidine; Zidovudine | 1998 |
Acute HIV syndrome after discontinuation of antiretroviral therapy in a patient treated before seroconversion.
Topics: Adult; Anti-HIV Agents; CD4-CD8 Ratio; Drug Therapy, Combination; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Male; Ritonavir; RNA, Viral; T-Lymphocytes, Cytotoxic; Zidovudine | 1998 |
Dual resistance to zidovudine and lamivudine in patients treated with zidovudine-lamivudine combination therapy: association with therapy failure.
Topics: Anti-HIV Agents; Cross-Sectional Studies; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Failure; Zidovudine | 1998 |
Profound anemia in a newborn infant of a mother receiving antiretroviral therapy.
Topics: Adult; Anemia; Anti-HIV Agents; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Leukocyte Count; Male; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zalcitabine; Zidovudine | 1998 |
Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sarcoma, Kaposi; Stavudine; Treatment Outcome; Viral Load; Viremia; Zalcitabine; Zidovudine | 1998 |
The M184V mutation in HIV-1 reverse transcriptase (RT) conferring lamivudine resistance does not result in broad cross-resistance to nucleoside analogue RT inhibitors.
Topics: Anti-HIV Agents; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Methionine; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Valine; Zalcitabine; Zidovudine | 1998 |
Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease.
Topics: Adult; Aged; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 1998 |
Persistence of HIV-1 variants harbouring the zidovudine resistance mutation at pol codon 215 in patients who respond to triple combination therapy.
Topics: Adult; Anti-HIV Agents; Codon; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Virus Latency; Zidovudine | 1998 |
Severe anoxic hepatic necrosis in an HIV-1-hepatitis C virus-co-infected patient starting antiretroviral triple combination therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination; Hepatitis C; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Necrosis; Red-Cell Aplasia, Pure; Reverse Transcriptase Inhibitors; Zidovudine | 1998 |
Antiretroviral triple therapy decreases HIV viral load but does not alter hepatitis C virus (HCV) serum levels in HIV-HCV-co-infected haemophiliacs.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Hemophilia A; Hepacivirus; Hepatitis C; HIV; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1998 |
Cost-effectiveness of antiviral drug therapy to reduce mother-to-child HIV transmission in sub-Saharan Africa.
Topics: Africa South of the Sahara; Anti-HIV Agents; Breast Feeding; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Health Care Costs; HIV Infections; HIV Seroprevalence; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Zidovudine | 1998 |
[HIV infection: DuPont Pharma presents the results of its antiretroviral agent].
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Evaluation; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viremia; Zidovudine | 1998 |
Comparison of two antiretroviral triple combinations including the protease inhibitor indinavir in children infected with human immunodeficiency virus.
Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infant; Lamivudine; Male; Reverse Transcriptase Inhibitors; Statistics, Nonparametric; Viral Load; Zidovudine | 1998 |
Prevalence of genotypic resistance to nucleoside analogues in antiretroviral-naive and antiretroviral-experienced HIV-infected patients in Spain.
Topics: Adult; Anti-HIV Agents; Cross-Sectional Studies; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zalcitabine; Zidovudine | 1998 |
Cost-effectiveness of chemoprophylaxis after occupational exposure to HIV.
Topics: Anti-HIV Agents; Cost-Benefit Analysis; HIV Infections; Humans; Indinavir; Lamivudine; Occupational Exposure; United States; Zidovudine | 1998 |
Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Virus Integration; Virus Latency; Virus Replication; Zidovudine | 1998 |
Prevalence of mutation associated to resistance with nucleoside analogues in a cohort of naïve HIV-1 positive subjects during the period 1984-1997.
Topics: Adult; Drug Resistance, Microbial; Female; HIV Infections; HIV Reverse Transcriptase; Humans; Lamivudine; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 1998 |
Therapeutic and other interventions to reduce the risk of mother-to-child transmission of HIV-1 in Europe. The European Collaborative Study.
Topics: Adult; Anti-HIV Agents; Breast Feeding; Cesarean Section; Cohort Studies; Didanosine; Europe; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prospective Studies; Risk Factors; Zidovudine | 1998 |
Comparison of the LiPA HIV-1 RT test, selective PCR and direct solid phase sequencing for the detection of HIV-1 drug resistance mutations.
Topics: Anti-HIV Agents; Codon; Didanosine; DNA Probes; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; Zalcitabine; Zidovudine | 1998 |
Analysis of antiretroviral nucleosides by electrospray ionization mass spectrometry and collision induced dissociation.
Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Gas Chromatography-Mass Spectrometry; Lamivudine; Models, Chemical; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Secondary Ion; Zalcitabine; Zidovudine | 1998 |
Alternative multidrug regimen provides improved suppression of HIV-1 replication over triple therapy.
Topics: Adult; Anti-HIV Agents; Data Interpretation, Statistical; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Virus Replication; Zidovudine | 1998 |
Clinical experience with adding delavirdine to combination therapy in patients in whom multiple antiretroviral treatment including protease inhibitors has failed.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Delavirdine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine | 1998 |
Occupational exposure to blood and body fluids: new postexposure prophylaxis recommendations. United States Occupational Safety and Health Administration.
Topics: Anti-HIV Agents; Blood-Borne Pathogens; Dental Staff; Dentistry; HIV Infections; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Mandatory Reporting; Occupational Exposure; Risk Factors; Risk Management; Surveys and Questionnaires; Zidovudine | 1998 |
Chemoprophylaxis after occupational exposure to human immunodeficiency virus in forensic autopsy.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Forensic Medicine; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Occupational Exposure; Zidovudine | 1998 |
Neurological efficacy of stavudine, zidovudine, and lamivudine.
Topics: AIDS Dementia Complex; Anti-HIV Agents; beta 2-Microglobulin; Blood-Brain Barrier; Brain; HIV-1; Humans; Lamivudine; Meninges; RNA, Viral; Stavudine; Virus Shedding; Zidovudine | 1998 |
Neurological efficacy of stavudine, zidovudine, and lamivudine.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Brain; Female; Follow-Up Studies; HIV-1; Humans; Indinavir; Lamivudine; Neopterin; RNA, Viral; Stavudine; Viral Load; Virus Replication; Zidovudine | 1998 |
Cerebrospinal fluid levels of antiretroviral medications: abstract and commentary.
Topics: Anti-HIV Agents; Blood-Brain Barrier; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Zidovudine | 1998 |
Clozapine treatment of HIV-associated psychosis--too much bone marrow toxicity?
Topics: Adult; Anti-HIV Agents; Antipsychotic Agents; Clozapine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Neutropenia; Psychotic Disorders; Zidovudine | 1998 |
Development of a new cartridge radioimmunoassay for determination of intracellular levels of lamivudine triphosphate in the peripheral blood mononuclear cells of human immunodeficiency virus-infected patients.
Topics: Animals; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Rabbits; Radioimmunoassay; Zidovudine | 1998 |
Taste and smell complaints in HIV-infected patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Clarithromycin; Didanosine; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Quality of Life; Ritonavir; Smell; Surveys and Questionnaires; Taste; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine | 1998 |
Progressive multifocal leukoencephalopathy following initiation of highly active antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Seropositivity; Humans; Indinavir; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Male; Viral Load; Zidovudine | 1998 |
[Weak antiviral effect of changing two nucleoside analogues combined with antiretroviral agents. 3TC and d4T after ZDU and ddi or ddc].
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1998 |
Effect of antiretroviral therapy and viral load on the perceived risk of HIV transmission and the need for safer sexual practices.
Topics: Anti-HIV Agents; Attitude to Health; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Lamivudine; Male; Protease Inhibitors; Reverse Transcriptase Inhibitors; Risk Factors; Sexual Behavior; Sexual Partners; Sexually Transmitted Diseases, Viral; Surveys and Questionnaires; Viral Load; Zidovudine | 1998 |
Cost of preventing HIV infection after sexual exposure.
Topics: Anti-HIV Agents; Cost-Benefit Analysis; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Models, Theoretical; Reproducibility of Results; Sexual Behavior; Zidovudine | 1998 |
Precipitous declines in hemoglobin levels associated with combination zidovudine and lamivudine therapy.
Topics: Adult; Anemia; Anti-HIV Agents; Drug Therapy, Combination; Female; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zidovudine | 1998 |
Acute generalized exanthematous pustulosis: a cutaneous adverse effect due to prophylactic antiviral therapy with protease inhibitor.
Topics: Acute Disease; Adult; Anti-HIV Agents; Diagnosis, Differential; Drug Eruptions; Exanthema; HIV Infections; Humans; Lamivudine; Male; Protease Inhibitors; Skin Diseases, Vesiculobullous; Zidovudine | 1998 |
Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Atrophy; Brain; Female; Humans; Ibuprofen; Indinavir; Lamivudine; Magnetic Resonance Imaging; Neurons; Neurotoxins; Nitric Oxide; Quinolinic Acid; Toxicity Tests; Tumor Necrosis Factor-alpha; Zidovudine | 1998 |
Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study.
Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation; Biomarkers; Female; HIV Infections; HLA-DR Antigens; Humans; Lamivudine; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Count; Male; Membrane Glycoproteins; NAD+ Nucleosidase; Prospective Studies; Ritonavir; RNA, Viral; T-Lymphocytes; Viral Load; Zidovudine | 1998 |
Phase III results of second-generation HIV protease inhibitor reported.
Topics: Anti-HIV Agents; Carbamates; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Sulfonamides; Viral Load; Zidovudine | 1998 |
Decay of HIV-1 DNA in patients receiving suppressive antiretroviral therapy.
Topics: Adult; Amino Acid Sequence; Anti-HIV Agents; Base Sequence; CD4 Lymphocyte Count; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; Genotype; Half-Life; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Longitudinal Studies; Male; Molecular Sequence Data; Mutation; Retrospective Studies; RNA, Viral; Zidovudine | 1998 |
HIV-1 peripheral neuropathy and combination antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nelfinavir; Nevirapine; Peripheral Nervous System Diseases; Saquinavir; Zidovudine | 1998 |
Report updates recommendations for health workers exposed to HIV.
Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Health Personnel; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Occupational Exposure; Practice Guidelines as Topic; United States; United States Public Health Service; Zidovudine | 1998 |
Immunologic and virologic response of HIV-2 infection to antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-2; Humans; Indinavir; Lamivudine; Male; Proviruses; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 1998 |
[Clinical case of the month. Apropos of pancytopenia in a seropositive patient].
Topics: Adult; Anemia, Aplastic; Anti-HIV Agents; Bone Marrow; HIV Infections; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Male; Pancytopenia; Stavudine; Zidovudine | 1998 |
Persistent parvovirus B19 related anemia of seven years' duration in an HIV-infected patient: complete remission associated with highly active antiretroviral therapy.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Erythrocyte Transfusion; HIV Infections; Humans; Immunoglobulins, Intravenous; Lamivudine; Male; Parvoviridae Infections; Parvovirus B19, Human; Red-Cell Aplasia, Pure; Remission Induction; Ritonavir; Saquinavir; Zidovudine | 1999 |
Genotypic and phenotypic resistance under zidovudine and lamivudine therapy in human immunodeficiency virus-infected children.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Resistance; Female; Genotype; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Phenotype; Zidovudine | 1999 |
Inhibition of human immunodeficiency virus type 1 replication by combination of transcription inhibitor K-12 and other antiretroviral agents in acutely and chronically infected cells.
Topics: Alkaloids; Anti-HIV Agents; Anti-Infective Agents; Benzylisoquinolines; Cell Line; Drug Synergism; Fluoroquinolones; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Nelfinavir; Nevirapine; NF-kappa B; Piperazines; Reverse Transcriptase Inhibitors; Tumor Necrosis Factor-alpha; Virus Replication; Zidovudine | 1999 |
Cheap treatment cuts HIV transmission.
Topics: Africa; Anti-HIV Agents; Controlled Clinical Trials as Topic; Drug Therapy, Combination; Ethics, Medical; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Labor, Obstetric; Lamivudine; Placebos; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 1999 |
Antiretroviral drugs: new agents, new combinations line up against HIV.
Topics: Antiviral Agents; Australia; Didanosine; Drug Therapy, Combination; Europe; HIV; HIV Infections; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine | 1996 |
PHS recommends preventive drugs for HIV exposures.
Topics: Antiviral Agents; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Pyridines; United States; United States Public Health Service; Virus Replication; Zalcitabine; Zidovudine | 1996 |
I have learned to hope.
Topics: Acquired Immunodeficiency Syndrome; Attitude to Death; Attitude to Health; Boston; Fear; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Radio; Reverse Transcriptase Inhibitors; Survivors; Zidovudine | 1996 |
Modelling the cost effectiveness of lamivudine/zidovudine combination therapy in HIV infection.
Topics: Adult; Cost-Benefit Analysis; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Models, Economic; Zidovudine | 1997 |
AIDS: the new drug war.
Topics: Acquired Immunodeficiency Syndrome; Black or African American; Dideoxynucleosides; Drug Combinations; Drug Industry; Humans; Investments; Lamivudine; Stavudine; United States; Zidovudine | 1998 |
The cost-effectiveness of treatment with lamivudine and zidovudine compared with zidovudine alone: a comparison of Markov model and trial data estimates.
Topics: Cost-Benefit Analysis; Drug Therapy, Combination; Health Care Costs; HIV Infections; Humans; Lamivudine; Markov Chains; Models, Econometric; Reverse Transcriptase Inhibitors; United States; Zidovudine | 1998 |
Early lipodystrophy occurring during post-exposure prophylaxis.
Topics: Adult; Anti-HIV Agents; HIV Infections; Homosexuality, Male; Humans; Lamivudine; Lipodystrophy; Male; Rape; Zidovudine | 1998 |
Persistent alterations in T-cell repertoire, cytokine and chemokine receptor gene expression after 1 year of highly active antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytokines; Female; Gene Expression; HIV Infections; HIV Protease Inhibitors; Humans; Interferon-gamma; Interleukin-10; Interleukin-13; Interleukin-2; Interleukin-4; Lamivudine; Longitudinal Studies; Male; Receptors, CCR3; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Interleukin; Receptors, Interleukin-12; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Messenger; Saquinavir; Zidovudine | 1999 |
Combination antiretroviral therapy including ritonavir in children infected with human immunodeficiency.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Zidovudine | 1999 |
Highly active antiretroviral therapy used to treat concurrent hepatitis B and human immunodeficiency virus infections.
Topics: Adult; Anti-HIV Agents; Biopsy, Needle; Drug Therapy, Combination; Gene Products, pol; Hepatitis B Antibodies; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Liver; Male; Zidovudine | 1999 |
[AZT and 3TC treatment in a pregnant woman with HIV infection].
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 1999 |
Modeling the long-term outcomes and costs of HIV antiretroviral therapy using HIV RNA levels: application to a clinical trial.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Cost-Benefit Analysis; Costs and Cost Analysis; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Models, Biological; Models, Economic; Outcome and Process Assessment, Health Care; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 1999 |
[Infectious diseases in 1998].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-HIV Agents; Antiviral Agents; Bacterial Vaccines; Blood Donors; Clinical Trials as Topic; Drug Therapy, Combination; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Interferons; Lamivudine; Middle Aged; Multicenter Studies as Topic; Pneumonia, Pneumococcal; Randomized Controlled Trials as Topic; Ribavirin; Streptococcus pneumoniae; Transfusion Reaction; Zidovudine | 1999 |
Salvage therapy with ritonavir-saquinavir plus two nucleoside reverse transcriptase inhibitors in patients failing with amprenavir-zidovudine-lamivudine.
Topics: Adult; Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; Salvage Therapy; Saquinavir; Sulfonamides; Zidovudine | 1999 |
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Interactions; Guanosine; Humans; Hydroxyurea; Inosine; Intracellular Fluid; Lamivudine; Pentoxifylline; Stavudine; U937 Cells; Zidovudine | 1999 |
Utilization of transgenic mice replicating high levels of hepatitis B virus for antiviral evaluation of lamivudine.
Topics: Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis, Viral, Animal; Humans; Lamivudine; Male; Mice; Mice, Transgenic; Time Factors; Treatment Outcome; Virus Replication; Zidovudine | 1999 |
Needle-stick injuries and HIV infection: a surgeon's personal experience and review of postexposure prophylaxis. St. Paul's Ocular AIDS Group.
Topics: Anti-HIV Agents; Dacryocystorhinostomy; Drug Therapy, Combination; HIV Infections; HIV Seropositivity; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Middle Aged; Needlestick Injuries; Occupational Exposure; Ophthalmology; Primary Prevention; Risk Factors; Zidovudine | 1999 |
Complete regression of AIDS-related Kaposi's sarcoma in a child treated with highly active antiretroviral therapy.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Child, Preschool; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Sarcoma, Kaposi; Treatment Outcome; Zidovudine | 1999 |
Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytotoxicity, Immunologic; Drug Therapy, Combination; Epitopes, T-Lymphocyte; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Longitudinal Studies; Reverse Transcriptase Inhibitors; Stavudine; T-Lymphocytes, Cytotoxic; Viral Load; Viremia; Zidovudine | 1999 |
Multiple drug resistance genotype causing failure of antiretroviral treatment in an HIV-infected patient heavily exposed to nucleoside analogues.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Resistance, Multiple; Drug Therapy, Combination; Genes, MDR; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nucleosides; Point Mutation; Zidovudine | 1999 |
Development and significance of the HIV-1 reverse transcriptase M184V mutation during combination therapy with lamivudine, zidovudine, and protease inhibitors.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Methionine; Point Mutation; Retrospective Studies; Reverse Transcriptase Inhibitors; Valine; Zidovudine | 1999 |
Antiviral effect of AZT versus stavudine in combination with lamivudine and indinavir in the context of a populational study.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Stavudine; Viremia; Zidovudine | 1999 |
Phenotypic changes in drug susceptibility associated with failure of human immunodeficiency virus type 1 (HIV-1) triple combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Nelfinavir; Phenotype; Salvage Therapy; Time Factors; Transfection; Treatment Failure; Zidovudine | 1999 |
IAS position paper on prevention of HIV 1 mother-to-child transmission. International Aids Society.
Topics: Anti-HIV Agents; Child, Preschool; Developing Countries; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Program Development; Reverse Transcriptase Inhibitors; Societies, Medical; Zidovudine | 1999 |
Quality of life in asymptomatic patients with early HIV infection initiating antiretroviral therapy. Swiss HIV Cohort Study.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Quality of Life; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Sickness Impact Profile; Zidovudine | 1999 |
The use of human immunodeficiency virus postexposure prophylaxis after successful artificial insemination.
Topics: Adult; Antiviral Agents; Female; HIV Infections; HIV Seropositivity; Humans; Indinavir; Insemination, Artificial, Heterologous; Lamivudine; Male; Pregnancy; Tissue Donors; Zidovudine | 1999 |
Rapid development of genotypic resistance to lamivudine when combined with zidovudine in pregnancy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA-Directed DNA Polymerase; Viral Load; Zidovudine | 1999 |
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues.
Topics: Acidosis, Lactic; Anti-HIV Agents; Child, Preschool; DNA, Mitochondrial; Female; France; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Maternal-Fetal Exchange; Mitochondrial Encephalomyopathies; Pregnancy; Prenatal Exposure Delayed Effects; Reference Values; Retrospective Studies; Zidovudine | 1999 |
Predictors of optimal virological response to potent antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV Seropositivity; Humans; Lamivudine; Male; Nelfinavir; Outcome Assessment, Health Care; Predictive Value of Tests; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load; Zidovudine | 1999 |
Pharmacokinetics of nelfinavir in an HIV patient with renal insufficiency.
Topics: Anti-HIV Agents; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Renal Insufficiency; Reverse Transcriptase Inhibitors; Zidovudine | 1999 |
Nucleoside analogues achieve high concentrations in seminal plasma: relationship between drug concentration and virus burden.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Semen; Viral Load; Zidovudine | 1999 |
[Pustulous psoriasis resistant to conventional treatment].
Topics: Adult; Antiviral Agents; Drug Resistance; Drug Therapy, Combination; HIV Seropositivity; Humans; Lamivudine; Male; Psoriasis; Saquinavir; Zidovudine | 1999 |
Severe anemia as a newly recognized side-effect caused by lamivudine.
Topics: Anemia; Anti-HIV Agents; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine | 1999 |
Saquinavir hard gel suppresses viral load insufficiently in HIV-infected patients naive to anti-retroviral therapy: a retrospective cohort study.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Controlled Clinical Trials as Topic; Denmark; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Multicenter Studies as Topic; Retrospective Studies; Ritonavir; RNA, Viral; Saquinavir; Viral Load; Zidovudine | 1999 |
Highly active anti-retroviral therapy (HAART) is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients.
Topics: Adult; Aged; Anti-HIV Agents; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1999 |
Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Adult; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; HIV Infections; HIV-1; HLA-DR Antigens; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Male; Membrane Glycoproteins; NAD+ Nucleosidase; Palatine Tonsil; Proviruses; T-Lymphocyte Subsets; Time Factors; Viremia; Virus Replication; Zidovudine | 1999 |
Advanced Hodgkin's disease in a pregnant HIV seropositive woman: favorable mother and baby outcome following combined anticancer and antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Female; HIV Seropositivity; Hodgkin Disease; Humans; Lamivudine; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Remission Induction; Stavudine; Zidovudine | 2000 |
Incidence and predictors of virologic failure of antiretroviral triple-drug therapy in a community-based cohort.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Disease Progression; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Ritonavir; RNA, Viral; Salvage Therapy; Saquinavir; Stavudine; Switzerland; Treatment Failure; Viral Load; Zalcitabine; Zidovudine | 1999 |
Effect of combination antiretroviral therapy on T-cell immunity in acute human immunodeficiency virus type 1 infection.
Topics: Acute Disease; Adult; Anti-HIV Agents; Candida; CD4 Lymphocyte Count; Chronic Disease; Cytokines; Cytotoxicity, Immunologic; Drug Therapy, Combination; Female; HIV Antigens; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Male; Middle Aged; Prospective Studies; T-Lymphocytes; Tetanus Toxoid; Viral Load; Zidovudine | 2000 |
Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy.
Topics: Adult; Aged; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocytes; Male; Middle Aged; Ritonavir; T-Lymphocyte Subsets; Thymus Gland; Tomography; Zidovudine | 2000 |
Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site.
Topics: Catalytic Domain; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Proline; Reverse Transcriptase Inhibitors; Thionucleosides; Thiophenes; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine | 2000 |
Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Phenotype; RNA, Viral; Treatment Failure; Viral Load; Zidovudine | 2000 |
Hydroxyurea interferes with antigen-dependent T-cell activation in vitro.
Topics: Candida albicans; HIV-1; Humans; Hydroxyurea; Lamivudine; Lymphocyte Activation; Phytohemagglutinins; Reverse Transcriptase Inhibitors; T-Lymphocytes; Zidovudine | 2000 |
Effortless unintentional smoking cessation after lamivudine-zidovudine-indinavir post-exposure anti-HIV chemoprophylaxis.
Topics: Adult; Anti-HIV Agents; HIV Infections; Humans; Indinavir; Lamivudine; Male; Smoking; Smoking Cessation; Zidovudine | 1999 |
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
Topics: AIDS Dementia Complex; Animals; Cells, Cultured; Didanosine; Dideoxynucleosides; Disease Models, Animal; HIV-1; Humans; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine | 2000 |
A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutagenesis, Site-Directed; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Zidovudine | 2000 |
Induction and maintenance treatment regimens for HIV-1 infection in vitro.
Topics: Anti-HIV Agents; Cell Line; DNA, Viral; HIV-1; Humans; Indinavir; Lamivudine; Zidovudine | 1999 |
Presence of genotypic resistance in nucleoside analogue-treated HIV-1-infected patients with undetectable viral load.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance; Genes, pol; Genotype; HIV-1; Humans; Lamivudine; Point Mutation; RNA, Viral; Zalcitabine; Zidovudine | 1999 |
Loss of lamivudine resistance in a zidovudine and lamivudine dual-resistant HIV-1 isolate after discontinuation of in vitro lamivudine drug pressure.
Topics: Anti-HIV Agents; Codon; Drug Resistance; Genotype; HIV-1; Humans; Lamivudine; Phenotype; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine | 1998 |
Drugs for HIV infection.
Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Costs; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine | 2000 |
Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor beta chain repertoire and reduces the level of T-cell oligoclonality.
Topics: Acute Disease; Anti-HIV Agents; Clone Cells; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Saquinavir; T-Lymphocytes, Cytotoxic; Viremia; Zidovudine | 2000 |
A model of HIV-1 pathogenesis that includes an intracellular delay.
Topics: Anti-HIV Agents; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Biological; Numerical Analysis, Computer-Assisted; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
Tolerability and side-effects of post-exposure prophylaxis for HIV infection.
Topics: Anti-HIV Agents; Drug Combinations; Drug Tolerance; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; London; Needlestick Injuries; Patient Compliance; Personnel, Hospital; Retrospective Studies; Zidovudine | 2000 |
Emergence of dual resistance to zidovudine and lamivudine in HIV-1-infected patients treated with zidovudine plus lamivudine as initial therapy.
Topics: Amino Acid Sequence; Anti-HIV Agents; Codon; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Zidovudine | 2000 |
Normalization of CD4+ cell numbers and reduced levels of memory CD8+ cells in blood and tonsillar tissue after highly active antiretroviral therapy in early HIV type-1 infection.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Male; Palatine Tonsil; Reverse Transcriptase Inhibitors; T-Lymphocyte Subsets; Time Factors; Viremia; Zidovudine | 2000 |
Early immune reconstitution after potent antiretroviral therapy in HIV-infected children correlates with the increase in thymus volume.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Cohort Studies; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Organ Size; Reverse Transcriptase Inhibitors; Stavudine; Thymus Gland; Viral Load; Zidovudine | 2000 |
The triple combination indinavir-zidovudine-lamivudine is highly synergistic.
Topics: Anti-HIV Agents; Cells, Cultured; Coloring Agents; Drug Synergism; HIV-1; Humans; Indinavir; Lamivudine; Tetrazolium Salts; Zidovudine | 2000 |
[First HIV triple therapy with one tablet].
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tablets; Zidovudine | 2000 |
Predicting the duration of antiviral treatment needed to suppress plasma HIV-1 RNA.
Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cohort Studies; Dideoxynucleosides; Furans; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lymph Nodes; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Sulfonamides; Time Factors; Viral Load; Viremia; Zidovudine | 2000 |
The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Base Sequence; Diphosphates; DNA, Viral; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Templates, Genetic; Zidovudine | 2000 |
Mitigation of hepato-cellular injury caused by HAART with glycyrrhizin compound in patients co-infected with HIV and HCV.
Topics: Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Combinations; Drug Therapy, Combination; Glycine; Glycyrrhetinic Acid; Hemophilia A; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1999 |
[A two-year follow-up of zidovudine plus lamivudine combined with indinavir in antivival naive HIV-infected patients].
Topics: Anti-HIV Agents; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
Amprenavir study results released.
Topics: Anti-HIV Agents; Carbamates; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sulfonamides; Viral Load; Zidovudine | 1999 |
Anti-human immunodeficiency virus type 1 (HIV-1) CD8(+) T-lymphocyte reactivity during combination antiretroviral therapy in HIV-1-infected patients with advanced immunodeficiency.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cell Lineage; Drug Therapy, Combination; Gene Products, gag; Gene Products, pol; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Interferon-gamma; Lamivudine; Longitudinal Studies; Lymphocyte Activation; Peptides; Phenotype; Phosphoproteins; Reverse Transcriptase Inhibitors; T-Lymphocytes, Cytotoxic; Viral Load; Viral Matrix Proteins; Zidovudine | 2000 |
The efficacy and tolerability of combination antiretroviral therapy in pregnancy: infant and maternal outcome.
Topics: Adolescent; Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Treatment Outcome; Zidovudine | 2000 |
Immune repopulation after HAART in previously untreated HIV-1-infected children. Paediatric European Network for Treatment of AIDS (PENTA) Steering Committee.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Immunologic Memory; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nelfinavir; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine | 2000 |
Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.
Topics: CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Polymerase Chain Reaction; Predictive Value of Tests; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zalcitabine; Zidovudine | 2000 |
Efavirenz in HIV infection.
Topics: Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Oxazines; Research Design; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2000 |
Highly active antiretroviral therapy inhibits cytokine production in HIV-uninfected subjects.
Topics: Adult; Anti-HIV Agents; Child; Cytokines; Drug Therapy, Combination; HIV Infections; HIV Seronegativity; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
[A case of HIV encephalopathy with dementia which showed significant improvement after the combination antiretroviral therapy].
Topics: AIDS Dementia Complex; Anti-HIV Agents; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Treatment Outcome; Zidovudine | 2000 |
HE2000 shows efficacy.
Topics: Animals; Anti-HIV Agents; Disease Models, Animal; Drugs, Investigational; Haplorhini; Lamivudine; Ritonavir; Simian Acquired Immunodeficiency Syndrome; Survival Analysis; Viral Load; Zidovudine | 1999 |
Cutaneous side effects induced by indinavir.
Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine | 2000 |
Zidovudine + lamivudine: new preparation. Fewer tablets required.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine | 1999 |
Simultaneous determination of zidovudine and lamivudine in human serum using HPLC with tandem mass spectrometry.
Topics: Anti-HIV Agents; Antibody Specificity; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Isotope Labeling; Lamivudine; Mass Spectrometry; Radioimmunoassay; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Zidovudine | 2000 |
Prevalence of primary resistance to zidovudine and lamivudine in drug-naive human immunodeficiency virus type-1 infected patients: high proportion of reverse transcriptase codon 215 mutant in circulating lymphocytes and free virus.
Topics: Anti-HIV Agents; Codon; DNA, Viral; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lymphocytes; Nucleic Acid Hybridization; Polymerase Chain Reaction; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2000 |
Failure to develop HIV infection after receipt of HIV-contaminated blood and postexposure prophylaxis.
Topics: Adolescent; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Transfusion Reaction; Zidovudine | 2000 |
Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Mass Spectrometry; Reference Standards; Reverse Transcriptase Inhibitors; Semen; Zidovudine | 2000 |
Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir.
Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Disease Reservoirs; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Semen; Stavudine; Viral Load; Zidovudine | 2000 |
Onset of HIV-1 antibody production after highly active antiretroviral therapy in a seronegative HIV-1-infected child.
Topics: Anti-HIV Agents; Antibody Formation; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Antibodies; HIV Infections; HIV Seronegativity; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Viremia; Zidovudine | 2000 |
[Human immunodeficiency virus: current pregnancy aspects].
Topics: Anti-HIV Agents; Cesarean Section; Drug Therapy, Combination; Female; HIV Infections; HIV-1; HIV-2; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 2000 |
[Antiretroviral drugs and pregnancy: apropos of an alert regarding mitochondrial pathology and nucleoside analogs].
Topics: Abnormalities, Drug-Induced; Animals; Anti-HIV Agents; Female; HIV Infections; Humans; Lamivudine; Mitochondrial Myopathies; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Risk; Zidovudine | 2000 |
Correlation between human immunodeficiency virus genotypic resistance and virologic response in patients receiving nelfinavir monotherapy or nelfinavir with lamivudine and zidovudine.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Mutation; Nelfinavir; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine | 2000 |
Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; HIV Wasting Syndrome; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Time Factors; Zidovudine | 2000 |
In vivo fluctuation of HTLV-I and HTLV-II proviral load in patients receiving antiretroviral drugs.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV-1; HTLV-I Infections; HTLV-II Infections; Human T-lymphotropic virus 1; Human T-lymphotropic virus 2; Humans; Lamivudine; Middle Aged; Proviruses; T-Lymphocytes; Viral Load; Zidovudine | 2000 |
[Evaluation of the effect of early and massive tritherapy on the expression of cellular factors potentially implicated in antiretroviral therapy resistance].
Topics: Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Microbial; Gene Expression; Indinavir; Lamivudine; Macaca fascicularis; Male; Nucleoside-Phosphate Kinase; RNA, Messenger; Simian Acquired Immunodeficiency Syndrome; Thymidine Kinase; Zidovudine | 2000 |
[Conditions of "thymidine analog mutations" (TAMs) in naive patients treated with different combinations of d4T].
Topics: Anti-HIV Agents; Drug Resistance; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zidovudine | 2000 |
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].
Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Drug Combinations; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Molecular Structure; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; T-Lymphocytes; Thionucleosides; Zidovudine | 2000 |
The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection.
Topics: Anti-HIV Agents; Carbamates; Dideoxynucleosides; Furans; HIV Antibodies; HIV Core Protein p24; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Lamivudine; Neutralization Tests; Ritonavir; Sulfonamides; Zidovudine | 2000 |
Esophageal ulcer caused by cytomegalovirus: resolution during combination antiretroviral therapy for acquired immunodeficiency syndrome.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Biopsy; CD4 Lymphocyte Count; Cytomegalovirus Infections; Drug Therapy, Combination; Endoscopy, Digestive System; Esophagitis; Humans; In Situ Hybridization; Lamivudine; Male; Nelfinavir; Ulcer; Wound Healing; Zidovudine | 2000 |
Intensification of background antiretroviral therapy with abacavir during low-level failure may restore optimal suppression.
Topics: Adult; Aged; Anti-HIV Agents; Dideoxynucleosides; Drug Resistance; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Failure; Viral Load; Zidovudine | 2000 |
Dynamics of HIV-1 viral load rebound among patients with previous suppression of viral replication.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Models, Biological; Predictive Value of Tests; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Virus Replication; Zidovudine | 2000 |
Mitochondrial and peroxisomal dysfunction following perinatal exposure to antiretroviral drugs.
Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Mitochondria; Perinatal Care; Peroxisomes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine | 2000 |
Immune reconstitution syndromes in human immuno-deficiency virus infection following effective antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cytomegalovirus Retinitis; Female; Hepatitis C; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Reverse Transcriptase Inhibitors; Zidovudine | 2000 |
[Cost effectiveness analysis of highly active antiretroviral therapy in HIV asymptomatic patients].
Topics: Adult; Anti-HIV Agents; Cost-Benefit Analysis; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nevirapine; Sickness Impact Profile; Spain; Stavudine; Viral Load; Zidovudine | 2000 |
3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.
Topics: Animals; Anti-HIV Agents; COS Cells; Dose-Response Relationship, Drug; Drug Resistance; Genetic Vectors; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Zidovudine | 2000 |
Postexposure prophylaxis for HIV after sexual assault.
Topics: Adult; Anti-HIV Agents; Chemoprevention; Female; HIV Infections; Humans; Lamivudine; Male; Retrospective Studies; San Francisco; Sex Offenses; Zidovudine | 2000 |
Assessing efficacy by measuring CD(4) counts and quality of life of AIDS patients treated with ritonavir, AZT and 3TC.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Body Weight; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Quality of Life; Ritonavir; Viral Load; Zidovudine | 2000 |
Abacavir: new preparation. Risks limit the value.
Topics: Adult; Antiviral Agents; Child; Clinical Trials as Topic; Cost-Benefit Analysis; Dideoxynucleosides; Drug Hypersensitivity; Drug Interactions; Drug Therapy, Combination; France; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Risk Assessment; Treatment Outcome; Zidovudine | 2000 |
Prevention of mother-child HIV transmission: progress and problems.
Topics: Africa; Antiviral Agents; Breast Feeding; Cesarean Section; Clinical Trials as Topic; Cohort Studies; Developing Countries; Drug Therapy, Combination; Europe; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mitochondrial Myopathies; Nervous System Diseases; Nevirapine; Pregnancy; Pregnancy Trimester, Third; Reverse Transcriptase Inhibitors; Thailand; United States; Zidovudine | 2000 |
Brief report: effect of antiretroviral agents on T-lymphocyte subset counts in healthy HIV-negative individuals. The Italian Registry on Antiretroviral Postexposure Prophylaxis.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Health Personnel; HIV Infections; HIV Seronegativity; Humans; Lamivudine; Longitudinal Studies; Lymphocyte Count; Male; Occupational Diseases; Retrospective Studies; T-Lymphocyte Subsets; Zidovudine | 2000 |
Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals.
Topics: Anti-HIV Agents; Chromatography, Ion Exchange; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; Humans; Lamivudine; Reference Standards; Thymine Nucleotides; Zidovudine | 2000 |
Antiviral resistance of biologic HIV-2 clones obtained from individuals on nucleoside reverse transcriptase inhibitor therapy.
Topics: Adult; Amino Acid Sequence; Consensus Sequence; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, Viral; Genotype; HIV Infections; HIV-2; Humans; Lamivudine; Male; Molecular Sequence Data; Phenotype; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine | 2000 |
A genotypic analysis of patients receiving Zidovudine with either Lamivudine, Didanosine or Zalcitabine dual therapy using the LiPA point mutation assay to detect genotypic variation at codons 41, 69, 70, 74, 184 and 215.
Topics: Anti-HIV Agents; Codon; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nucleic Acid Hybridization; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine | 2000 |
[Prevalence of primary mutations in human immunodeficiency virus with resistance to nucleoside analogues in previously untreated patients from Andalusia. Andalusian Group for the Study of Infectious diseases (GAEI)].
Topics: Adult; Anti-HIV Agents; CD4 Antigens; Codon; Data Interpretation, Statistical; DNA, Viral; Drug Resistance, Microbial; Female; Genotype; HIV; HIV Infections; Humans; Lamivudine; Male; Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Viral Load; Zidovudine | 2000 |
Multicenter review of protease inhibitors in 89 pregnancies.
Topics: Adolescent; Adult; Antiretroviral Therapy, Highly Active; Apgar Score; CD4-Positive T-Lymphocytes; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Linear Models; Multicenter Studies as Topic; Pregnancy; Pregnancy Complications, Infectious; Puerto Rico; Regression Analysis; Retrospective Studies; Reverse Transcriptase Inhibitors; Surveys and Questionnaires; United States; Viral Load; Zidovudine | 2000 |
Sustained responses to dual nucleoside therapy in women.
Topics: Adult; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine | 2000 |
Simultaneous quantitation of the 5'-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Mass Spectrometry; Monocytes; Reference Standards; Sensitivity and Specificity; Stavudine; Thymine Nucleotides; Zidovudine | 2000 |
Oral lesions in HIV/AIDS patients undergoing highly active antiretroviral treatment including protease inhibitors: a new face of oral AIDS?
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Candidiasis, Oral; Case-Control Studies; CD4 Lymphocyte Count; Female; Gingivitis; Herpes Labialis; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Leukoplakia, Hairy; Male; Middle Aged; Mouth Diseases; Periodontitis; Prevalence; Viral Load; Xerostomia; Zidovudine | 2000 |
Selective expansion of a minor proportion of drug-resistant HIV-1 by antiretroviral pressure in vitro.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Drug Resistance, Microbial; Genetic Variation; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Oligonucleotide Array Sequence Analysis; Phenotype; Reverse Transcriptase Inhibitors; Selection, Genetic; Zidovudine | 2000 |
Reduction in CD8+ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Depression, Chemical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Immunity, Cellular; Indinavir; Lamivudine; Lymphocyte Count; Male; Middle Aged; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Refusal; Viral Load; Viremia; Zidovudine | 2001 |
From the food and drug administration.
Topics: Administrative Personnel; Anti-HIV Agents; Brachytherapy; Catheterization; Coronary Disease; Dideoxynucleosides; Drug Combinations; Equipment and Supplies; Humans; Lamivudine; Recurrence; Stents; Technology, Radiologic; United States; United States Food and Drug Administration; Zidovudine | 2001 |
Protease inhibitor therapy in HIV-infected children.
Topics: Adolescent; Age Factors; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Patient Compliance; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2000 |
Effects of prenatal AZT+3TC treatment on open field behavior and responsiveness to scopolamine in adult mice.
Topics: Animals; Behavior, Animal; Female; Lamivudine; Male; Mice; Muscarinic Antagonists; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Scopolamine; Zidovudine | 2000 |
Trizivir on the market.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 2001 |
Prenatal exposure to anti-HIV drugs: neurobehavioral effects of zidovudine (AZT) + lamivudine (3TC) treatment in mice.
Topics: Animals; Anti-HIV Agents; Avoidance Learning; Body Weight; Female; Gestational Age; Hand Strength; Homing Behavior; Lamivudine; Male; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reflex; Social Behavior; Zidovudine | 2001 |
Primary HIV-1 drug resistance in Spain before and after the introduction of protease inhibitors.
Topics: Anti-HIV Agents; Codon; Drug Resistance, Microbial; Genotype; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Lamivudine; Mutation; Polymorphism, Genetic; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zidovudine | 2001 |
Analysis of HIV-1 mutation patterns in patients failing antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Mutation; Nelfinavir; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Saquinavir; Treatment Failure; Zidovudine | 2001 |
Indinavir, zidovudine, lamivudine: 3-year follow-up.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Kidney Calculi; Lamivudine; Risk Factors; Zidovudine | 2001 |
Feasibility of postexposure prophylaxis (PEP) against human immunodeficiency virus infection after sexual or injection drug use exposure: the San Francisco PEP Study.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Contact Tracing; Counseling; Didanosine; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Compliance; Reverse Transcriptase Inhibitors; Risk Factors; Risk-Taking; Sexually Transmitted Diseases, Viral; Substance Abuse, Intravenous; Time Factors; Zidovudine | 2001 |
Increased turnover of CCR5+ and redistribution of CCR5- CD4 T lymphocytes during primary human immunodeficiency virus type 1 infection.
Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Dideoxynucleosides; Epstein-Barr Virus Infections; Flow Cytometry; Furans; Genotype; HIV Infections; HIV-1; Humans; Immunoglobulin M; Lamivudine; Longitudinal Studies; Male; Proto-Oncogene Proteins c-bcl-2; Receptors, CCR5; Sulfonamides; Time Factors; Zidovudine | 2001 |
Association between high serum prolactin levels and concomitant infections in HIV-infected patients.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Anti-Infective Agents; CD4-CD8 Ratio; Female; HIV Infections; Humans; Immunoglobulins; Indinavir; Lamivudine; Male; Prolactin; Sex Factors; T-Lymphocyte Subsets; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Zidovudine | 2001 |
FDA approves Trizivir for HIV infection.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Approval; Drug Combinations; HIV Infections; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine | 2000 |
Triple-drug tablet approved for HIV infection.
Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Dideoxynucleosides; Drug Combinations; Drug Labeling; HIV Infections; Humans; Lamivudine; Tablets; Zidovudine | 2001 |
Serious adverse events attributed to nevirapine regimens for postexposure prophylaxis after HIV exposures--worldwide, 1997-2000.
Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; HIV Infections; Humans; Lamivudine; Liver Failure; Male; Nevirapine; Occupational Exposure; Reverse Transcriptase Inhibitors; Rhabdomyolysis; Zidovudine | 2001 |
Treatment interruption after one year of triple nucleoside analogue therapy for primary HIV infection.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Time Factors; Viral Load; Zidovudine | 2001 |
[Acquired immunodeficiency syndrome-associated progressive multifocal leukoencephalopathy treated with highly active anti-retroviral therapy].
Topics: Acquired Immunodeficiency Syndrome; Aged; Antiretroviral Therapy, Highly Active; Humans; Indinavir; JC Virus; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Male; Treatment Outcome; Zidovudine | 2000 |
In vitro evolution of the human immunodeficiency virus type 1 gag-protease region and maintenance of reverse transcriptase resistance following prolonged drug exposure.
Topics: Drug Resistance, Microbial; Drug Resistance, Multiple; Evolution, Molecular; Gene Products, gag; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Microbial Sensitivity Tests; Molecular Sequence Data; Reverse Transcriptase Inhibitors; Zidovudine | 2001 |
Quantification of HIV-1 proviral DNA in patients with undetectable plasma viremia over long-term highly active antiretroviral therapy.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; DNA, Viral; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Polymerase Chain Reaction; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viremia; Zidovudine | 2000 |
Primary genotypic and phenotypic HIV-1 drug resistance in recent seroconverters in Madrid.
Topics: Drug Resistance, Microbial; Drug Resistance, Multiple; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Protease Inhibitors; Reverse Transcriptase Inhibitors; Spain; Viral Load; Zidovudine | 2001 |
Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.
Topics: Animals; Anti-HIV Agents; Female; GABA Agonists; GABA-A Receptor Agonists; Habituation, Psychophysiologic; Lamivudine; Male; Mice; Motor Activity; Muscimol; Pain Measurement; Pregnancy; Prenatal Exposure Delayed Effects; Reaction Time; Time Factors; Zidovudine | 2001 |
[Bilateral hip necrosis, corticoids, and human immunodeficiency virus protease inhibitors].
Topics: Aged; Antiretroviral Therapy, Highly Active; Dexamethasone; Didanosine; Femur Head Necrosis; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Prednisone; Zidovudine | 2001 |
Failure of postexposure prophylaxis after sexual exposure to HIV.
Topics: Adult; Antiretroviral Therapy, Highly Active; Copulation; Female; HIV Antibodies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Treatment Failure; Viral Load; Zidovudine | 2001 |
Residual human immunodeficiency virus (HIV) Type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years.
Topics: Cohort Studies; DNA, Viral; Female; Genitalia; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Longitudinal Studies; Lymph Nodes; Male; Molecular Sequence Data; Randomized Controlled Trials as Topic; RNA, Viral; Time Factors; Viral Load; Viremia; Virus Replication; Zidovudine | 2001 |
Reduced HIV-stimulated T-helper cell reactivity in cord blood with short-course antiretroviral treatment for prevention of maternal-infant transmission.
Topics: Amino Acid Sequence; Anti-HIV Agents; Clinical Trials as Topic; Female; Fetal Blood; Gene Products, env; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Molecular Sequence Data; Peptide Fragments; South Africa; T-Lymphocytes, Helper-Inducer; Zidovudine | 2001 |
[Management of pregnant women infected with HIV at Bichat Hospital between 1990 and 1998: analysis of 202 pregnancies].
Topics: Africa South of the Sahara; Antiviral Agents; Cesarean Section; Female; France; Hepatitis B; Hepatitis C; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Papillomaviridae; Papillomavirus Infections; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Sexually Transmitted Diseases; Zidovudine | 2001 |
Viral excretion in cervicovaginal secretions of HIV-1-infected women receiving antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Viral; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Longitudinal Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Statistics, Nonparametric; Viral Load; Viremia; Virus Shedding; Zidovudine | 2001 |
Combination prophylaxis for prevention of maternal-infant HIV transmission: beyond 076.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 2001 |
Vertical HIV-1 transmission: prophylaxis and paediatric follow-up.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Ritonavir; Viral Load; Zidovudine | 2001 |
Tolerability of postexposure prophylaxis with zidovudine, lamivudine, and nelfinavir for human immunodeficiency virus infection.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Nelfinavir; Prospective Studies; Reverse Transcriptase Inhibitors; Zidovudine | 2001 |
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Thymine Nucleotides; Zalcitabine; Zidovudine | 2001 |
Impact of antiretroviral therapy on hepatitis C viraemia in HIV-infected patients.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Hepatitis C; HIV Infections; Humans; Lamivudine; RNA, Viral; Viremia; Zidovudine | 1996 |
Results of long-term follow-up of HIV-infected patients treated with lamivudine monotherapy, followed by a combination of lamivudine and zidovudine.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Zidovudine | 1997 |
Hypercholesterolemia in a health care worker receiving thyroxine after postexposure prophylaxis for human immunodeficiency virus infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Interactions; Female; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Indinavir; Lamivudine; Nelfinavir; Occupational Exposure; Reverse Transcriptase Inhibitors; Thyroxine; Zidovudine | 2001 |
AIDS treatments seek to eradicate virus, restore immunity.
Topics: Adjuvants, Immunologic; Anti-HIV Agents; Combined Modality Therapy; HIV Infections; Humans; Lamivudine; Ritonavir; Thymus Gland; Viral Load; Zidovudine | 1996 |
3TC approved.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Drug Approval; Drug Therapy, Combination; Humans; Lamivudine; Zidovudine | 1996 |
Research study of combination AIDS therapies underway.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Zidovudine | 1996 |
ACTG 315 drug cocktail restores immune function.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Ritonavir; RNA, Viral; Viral Load; Zidovudine | 1997 |
Undetectable HIV levels after triple therapy with indinavir.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; RNA, Viral; Viral Load; Zidovudine | 1997 |
ACTG 320 trial halted as three-drug arm proves superior.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; United States; Zidovudine | 1997 |
Anti-HIV effects of nelfinavir reported after ten months of combination therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphoid Tissue; Nelfinavir; Zidovudine | 1997 |
HAART therapy: dividing the epidemic?
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Zidovudine | 1997 |
First clinical data presented on FortovAse.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Saquinavir; Zidovudine | 1997 |
Ritonavir pediatric study results reported.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Ritonavir; Zidovudine | 1998 |
Head-to-head study of protease inhibitors.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Zidovudine | 1998 |
Data in from first head-to-head protease inhibitor.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Viral Load; Zidovudine | 1998 |
Double protease inhibitor regimens with amprenavir show promise.
Topics: Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Sulfonamides; Viral Load; Zidovudine | 1998 |
AZT studies reinforce benefits of combination.
Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Didanosine; Drug Synergism; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Lymphocyte Count; Zalcitabine; Zidovudine | 1995 |
Combination 3TC/AZT therapy shows promise.
Topics: CD4 Lymphocyte Count; Codon; Drug Resistance; Drug Therapy, Combination; Drug Tolerance; HIV Infections; Humans; Lamivudine; Mutation; Zalcitabine; Zidovudine | 1995 |
Clinical progress and transmission perils stressed at second human retroviruses conference.
Topics: Acyclovir; AIDS Vaccines; AIDS-Related Opportunistic Infections; Antineoplastic Agents; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Herpesviridae; HIV Infections; Humans; Interleukin-2; Lamivudine; Lymphoma, Non-Hodgkin; Retroviridae; Sarcoma, Kaposi; Zalcitabine; Zidovudine | 1995 |
AIDS task force grapples with faster access to protease drugs.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Approval; Drug Design; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Treatment Outcome; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
AZT + 3TC: early results promising.
Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamivudine; Zalcitabine; Zidovudine | 1995 |
Treatment briefs.
Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Industry; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Nerve Growth Factors; Nervous System Diseases; Pyridines; Recombinant Proteins; Stavudine; Zalcitabine; Zidovudine | 1995 |
3TC: the good news and the bad news.
Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; Europe; HIV Infections; Humans; Lamivudine; United States; Zalcitabine; Zidovudine | 1995 |
What we know about anti-HIV drugs.
Topics: Antiviral Agents; Didanosine; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Zalcitabine; Zidovudine | 1995 |
Lamivudine useful against hepatitis B-HIV co-infection.
Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Virus Replication; Zalcitabine; Zidovudine | 1995 |
Combination antiretroviral treatment: new views, evolving practices.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Cells, Cultured; Clinical Trials as Topic; Drug Administration Schedule; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
Topics: Acyclovir; Administration, Oral; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1995 |
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Approval; Drug Combinations; Drug Therapy, Combination; Health Services Accessibility; Humans; Insurance, Health; Lamivudine; Managed Care Programs; United States; Zalcitabine; Zidovudine | 1995 |
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1995 |
3TC: now available again up to CD4 of 300.
Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Industry; Drug Therapy, Combination; Humans; Lamivudine; Patient Selection; United States; Zalcitabine; Zidovudine | 1995 |
A closer look at 3TC. Interview by Mark Mascolini.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Hepatitis B; HIV Infections; Humans; Lamivudine; Zalcitabine; Zidovudine | 1995 |
Antiretroviral drug resistance.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Viremia; Zalcitabine; Zidovudine | 1995 |
A Lisbon traviata. Are clinicians ready to sing addio to monotherapy and libiamo to combinations?
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Indinavir; Interleukin-2; Lamivudine; Mutation; Pyridines; RNA, Viral; Zalcitabine; Zidovudine | 1995 |
Update on clinical trials of combination therapies for HIV infection.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; RNA-Directed DNA Polymerase; Stavudine; Zalcitabine; Zidovudine | 1995 |
Protease inhibitors and prevention of cross resistance.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Carbamates; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nelfinavir; Pyridines; Quinolines; Saquinavir; Sulfonamides; Zalcitabine; Zidovudine | 1995 |
3TC and saquinavir: we need them now.
Topics: Antiviral Agents; Drug Approval; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
Conference looks at HIV drug resistance.
Topics: Antiviral Agents; Carbamates; CD4 Lymphocyte Count; Drug Resistance, Microbial; Furans; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Sulfonamides; Thiazoles; Valine; Viremia; Zalcitabine; Zidovudine | 1995 |
Roaches of inner space.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Lamivudine; Mutation; T-Lymphocytes, Cytotoxic; Virulence; Virus Replication; Zalcitabine; Zidovudine | 1995 |
An interview with Charles A.B. Boucher, MD, PhD. Interview by Mark Mascolini.
Topics: Antiviral Agents; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Mutation; RNA, Viral; Zalcitabine; Zidovudine | 1995 |
FDA triple header. Food and Drug Administration.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Mutation; Quinolines; Salvage Therapy; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
3TC/AZT: just another combination.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Zalcitabine; Zidovudine | 1995 |
Combination therapy increases survival.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1995 |
Lamivudine (3TC) approved for combination use with AZT.
Topics: Adult; Antiviral Agents; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Zalcitabine; Zidovudine | 1995 |
To treat or not to treat--approaches to antiretroviral therapy. Interview by Anthony J. Japour.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Didanosine; Drug Therapy, Combination; HIV; Humans; Lamivudine; Practice Patterns, Physicians'; RNA, Viral; Zalcitabine; Zidovudine | 1996 |
Major protease inhibitor triple combination trial begins soon: CD4 under 200, AZT experienced, 3TC naive.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Zalcitabine; Zidovudine | 1995 |
3TC approved: now for the tough questions.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Zalcitabine; Zidovudine | 1995 |
Merck protease inhibitor: more news from Retroviruses Conference.
Topics: CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Zalcitabine; Zidovudine | 1996 |
Potent new AIDS drugs underscore promise of combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Approval; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
Clinicians experiment with post-exposure drug pairs.
Topics: Antiviral Agents; Drug Synergism; Drug Therapy, Combination; Health Personnel; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Needlestick Injuries; Occupational Exposure; Zalcitabine; Zidovudine | 1996 |
Protease inhibitors shine in triple combinations.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Ritonavir; Thiazoles; Valine; Zalcitabine; Zidovudine | 1996 |
Europe out of step with the US.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Costs; Europe; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Ritonavir; Saquinavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine | 1996 |
Back to the nukes.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1996 |
A surprisingly potent nucleoside analogue.
Topics: Adult; Antiviral Agents; HIV Infections; HIV-1; Humans; Lamivudine; Nucleosides; RNA, Viral; Zalcitabine; Zidovudine | 1996 |
AZT and 3TC.
Topics: CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zalcitabine; Zidovudine | 1996 |
CDC takes aggressive stance on postexposure prophylaxis. Centers for Disease Control and Prevention.
Topics: Antiviral Agents; Blood-Borne Pathogens; Centers for Disease Control and Prevention, U.S.; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Exposure; Pyridines; Risk Factors; United States; Zalcitabine; Zidovudine | 1996 |
Nipping HIV in the bud.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine | 1996 |
Top AIDS researchers' strategy for antiretroviral treatment.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Patient Compliance; Practice Guidelines as Topic; RNA, Viral; Stavudine; Zalcitabine; Zidovudine | 1996 |
3TC: combination trial stopped early as clinical benefit shown.
Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Placebos; Treatment Failure; Zalcitabine; Zidovudine | 1996 |
Eradication of HIV: the cutting edge of clinical trial design.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Pyridines; Zalcitabine; Zidovudine | 1996 |
Outdated yet out-of-reach: AIDS society treatment guidelines at the International Conference.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Decision Making; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Zalcitabine; Zidovudine | 1996 |
Update on antivirals.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 1996 |
New findings bring hope to Vancouver AIDS conference.
Topics: Adult; AIDS Vaccines; Antiviral Agents; Clinical Trials as Topic; Developing Countries; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine | 1996 |
ddI and d4T plus protease inhibitors.
Topics: Anti-HIV Agents; Didanosine; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine | 1996 |
Dethroning AZT.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; Oxazines; Stavudine; Viral Load; Zidovudine | 1997 |
Study shows three drugs better than two.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Stavudine; United States; Zidovudine | 1997 |
Study confirms that protease inhibitor cocktail can delay HIV disease progression and death.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; United States; Zidovudine | 1997 |
NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chemokines; Clinical Trials as Topic; Clone Cells; Dendritic Cells; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-10; Killer Cells, Natural; Lamivudine; Male; Nevirapine; Pyridines; Receptors, Cytokine; Reverse Transcriptase Inhibitors; Ritonavir; Virus Replication; Zalcitabine; Zidovudine | 1997 |
Nelfinavir at six months.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Sulfonic Acids; Viral Load; Zidovudine | 1997 |
ACTG 320: last of the body count trials?
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; Ethics, Medical; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zidovudine | 1997 |
Nelfinavir - major trial results at retroviruses conference.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Stavudine; Sulfonic Acids; Viral Load; Zidovudine | 1997 |
New recommendations on health care worker exposure to HIV.
Topics: Anti-HIV Agents; Disease Transmission, Infectious; Drug Therapy, Combination; Guidelines as Topic; Health Personnel; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Risk Factors; Viral Load; Zidovudine | 1996 |
Spring cleaning in trial land.
Topics: Anti-HIV Agents; Brazil; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Stavudine; United States; Viral Load; Zidovudine | 1997 |
Newly approved PI provides treatment options.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Sulfonic Acids; Viral Load; Zidovudine | 1997 |
Treating a survivor.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Counseling; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mycobacterium avium-intracellulare Infection; Pneumonia, Pneumocystis; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 1997 |
3-drug therapy reduces deaths and new AIDS-related illnesses by 50%.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 1997 |
Nelfinavir (Viracept).
Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Isoquinolines; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Sulfonic Acids; United States; United States Food and Drug Administration; Viral Load; Virus Replication; Zidovudine | 1997 |
141 (Vertex-478).
Topics: Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Clinical Trials, Phase II as Topic; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Sulfonamides; Viral Load; Zidovudine | 1997 |
Experience with PEP finds most patients stop early.
Topics: Anti-HIV Agents; British Columbia; Drug Therapy, Combination; Female; Health Services Accessibility; HIV Infections; Homosexuality, Male; Humans; Lamivudine; Male; Occupational Diseases; Patient Compliance; Sexually Transmitted Diseases; Time Factors; United States; Zidovudine | 1997 |
Combo therapy for children and adolescents.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Infant; Lamivudine; Zidovudine | 1997 |
Two drugs better than one for children.
Topics: Anti-HIV Agents; Child; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine | 1997 |
What you need to know about Combivir.
Topics: Anti-HIV Agents; Drug Combinations; Guidelines as Topic; HIV Infections; Humans; Lamivudine; Patient Compliance; Zidovudine | 1998 |
ACTG 343: three drugs better than two for maintaining HIV suppression.
Topics: AIDS Vaccines; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Viral Load; Zidovudine | 1998 |
New ways to take old drugs.
Topics: Anti-HIV Agents; Biological Availability; Drug Combinations; Drug Storage; HIV Infections; Humans; Lamivudine; Saquinavir; Zidovudine | 1998 |
Reevaluating initial therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Polymerase Chain Reaction; Stavudine; Viral Load; Zidovudine | 1998 |
New drugs: amprenavir and abacavir.
Topics: Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Sulfonamides; Viral Load; Zidovudine | 1998 |
New guidelines issued for occupational exposures.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Occupational Exposure; Practice Guidelines as Topic; United States; United States Public Health Service; Zidovudine | 1998 |
Giving improper dose of HIV drug is not proof of indifference.
Topics: Anti-HIV Agents; Disabled Persons; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Prisoners; Reverse Transcriptase Inhibitors; Texas; Zidovudine | 1998 |
Updated postexposure guidelines stress need for expert advice.
Topics: Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Drug Therapy, Combination; Female; Guidelines as Topic; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Occupational Diseases; Occupational Exposure; Pregnancy; Registries; United States; Zidovudine | 1998 |
Registry finds 3 drugs most favored PEP regimen.
Topics: Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Drug Combinations; Drug Therapy, Combination; Guidelines as Topic; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Diseases; Occupational Exposure; Registries; United States; Zidovudine | 1998 |
New drugs on the horizon.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; Sulfonamides; United States; Zidovudine | 1998 |
Lower dose maintenance therapy?
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; RNA, Viral; Viral Load; Zidovudine | 1998 |
First once-daily drug simplifies dosing, offers new options in HIV-1 treatment.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Patient Compliance; Reverse Transcriptase Inhibitors; Zidovudine | 1998 |
A new approach to initial antiretroviral therapy: protease-sparing combination regimens.
Topics: Alkynes; Anti-HIV Agents; Antineoplastic Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Drugs, Investigational; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Lamivudine; Lipodystrophy; Oxazines; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine | 1998 |
Triple-drug therapy may mean lifelong commitment.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; France; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Patient Compliance; United States; Zidovudine | 1999 |
A new HAART on the horizon says the proof is in the potency.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Oxazines; Patient Compliance; Pregnancy; Reverse Transcriptase Inhibitors; Zidovudine | 1999 |
New study shows efavirenz effective with d4T and 3TC.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cerebrospinal Fluid; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Vagina; Viral Load; Zidovudine | 1999 |
Promising findings from the PETRA study of perinatal transmission.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Randomized Controlled Trials as Topic; South Africa; Tanzania; Uganda; Zidovudine | 1999 |
Antiretrovirals for HIV nephropathy?
Topics: Adult; AIDS-Associated Nephropathy; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Kidney Function Tests; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 1999 |
Nukes alone.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; France; HIV Infections; Humans; Lamivudine; Zidovudine | 1999 |
[A rare etiology of hepatic steatosis associated with lactic acidosis: the toxicity of antiviral nucleoside analogues].
Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Antimetabolites; Didanosine; Fatal Outcome; Fatty Liver; Female; HIV Seropositivity; Humans; Lamivudine; Microscopy, Electron; Mitochondria, Liver; Stavudine; Zidovudine | 2001 |
[Compact therapy with 2 tablets daily. Initial triple combination tablet simplifies HIV therapy].
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; HIV Infections; Humans; Lamivudine; Patient Compliance; Zidovudine | 2001 |
[Results of the TRIZAL Study. Therapy change with positive concomitant effect].
Topics: Anti-HIV Agents; Cholesterol; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Treatment Outcome; Triglycerides; Zidovudine | 2001 |
Residual human immunodeficiency virus type 1 infection in lymphoid tissue during highly active antiretroviral therapy: quantitation and virus characterization.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Disease Progression; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Longitudinal Studies; Lymphoid Tissue; Phenotype; Proviruses; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Viral Load; Viremia; Virus Replication; Zidovudine | 2001 |
CT appearances of HIV-related lipodystrophy syndrome.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Mass Index; HIV Infections; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Tomography, X-Ray Computed; Treatment Outcome; Zidovudine | 2001 |
Choosing which nuke to use first.
Topics: Didanosine; Dideoxynucleosides; Drug Administration Schedule; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2001 |
Domestic cat model for predicting human nucleoside analogue pharmacokinetics in blood and seminal plasma.
Topics: Animals; Anti-HIV Agents; Cats; Humans; Lamivudine; Male; Models, Animal; Semen; Zidovudine | 2001 |
Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs.
Topics: Amino Acid Sequence; Anti-HIV Agents; Base Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Evolution, Molecular; Genetic Heterogeneity; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Insertional; Phylogeny; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Time Factors; Zidovudine | 2001 |
[Symptomatic hyperlactemia in patients infected with the human immunodeficiency virus treated with nucleoside analogs].
Topics: Adult; Anti-HIV Agents; Didanosine; Female; HIV Infections; HIV Reverse Transcriptase; Humans; Lactic Acid; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zidovudine | 2001 |
Prevalence and predictive value of intermittent viremia with combination hiv therapy.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Predictive Value of Tests; Prevalence; Proportional Hazards Models; Retrospective Studies; RNA, Viral; Viral Load; Viremia; Virus Replication; Zidovudine | 2001 |
Long-term evaluation of T-cell subset changes after effective combination antiretroviral therapy during asymptomatic HIV-infection.
Topics: Anti-HIV Agents; Case-Control Studies; Female; HIV Infections; HLA-DR Antigens; Humans; Lamivudine; Leukocyte Common Antigens; Longitudinal Studies; Lymphocyte Count; Male; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Ritonavir; T-Lymphocyte Subsets; Viral Load; Zidovudine | 2001 |
Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV Antibodies; HIV Core Protein p24; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Hypergammaglobulinemia; Immunoglobulin G; Lamivudine; Male; Middle Aged; Retrospective Studies; Ritonavir; RNA, Viral; Treatment Failure; Viral Load; Zidovudine | 2001 |
Lipid abnormalities in a healthcare worker receiving HIV prophylaxis.
Topics: Adult; Allied Health Personnel; Anti-HIV Agents; Cholesterol; Cholesterol, LDL; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Lamivudine; Needlestick Injuries; Nelfinavir; Practice Guidelines as Topic; Renal Dialysis; Reverse Transcriptase Inhibitors; Zidovudine | 2001 |
Neurological disorders after zidovudine exposure in utero.
Topics: Female; France; HIV Infections; Humans; Infant, Newborn; Lamivudine; Mitochondria; Neurotoxicity Syndromes; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; United States; Zidovudine | 1999 |
Differential susceptibility of retroviruses to nucleoside analogues.
Topics: Animals; Antiviral Agents; Cell Line; Cricetinae; Didanosine; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lamivudine; Mink; Nucleosides; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Zalcitabine; Zidovudine | 2001 |
Antiretroviral rounds. When success is a pain.
Topics: Abdominal Pain; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Oxazines; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2001 |
Approval comes with warning.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Approval; Drug Combinations; Drug Hypersensitivity; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine | 2001 |
An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Brain; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Magnetic Resonance Imaging; Motor Neuron Disease; Nelfinavir; Neurologic Examination; Treatment Outcome; Zidovudine | 2001 |
[Acceptance of antiretroviral therapy. HIV-infected patients assess convenient triple combination].
Topics: Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Patient Acceptance of Health Care; Patient Compliance; Zidovudine | 2001 |
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; HIV Infections; HIV-1; Lamivudine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Thymine Nucleotides; Transfection; Zidovudine | 2001 |
Combined effect of zidovudine (ZDV), lamivudine (3TC) and abacavir (ABC) antiretroviral therapy in suppressing in vitro FIV replication.
Topics: Animals; Anti-HIV Agents; Cats; Cell Line; Dideoxynucleosides; Drug Synergism; Drug Therapy, Combination; Feline Acquired Immunodeficiency Syndrome; Humans; Hydroxyurea; Immunodeficiency Virus, Feline; Kidney; Lamivudine; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine | 2002 |
Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice.
Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atrial Natriuretic Factor; Calcium-Transporting ATPases; Cardiomyopathies; Drug Therapy, Combination; Echocardiography; Gene Expression; HIV Protease Inhibitors; Indinavir; Lactic Acid; Lamivudine; Mice; Mice, Transgenic; Microscopy, Electron; Myocardium; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Zidovudine | 2001 |
Absolute lymphocyte count as surrogate for CD4+ cell count in monitoring response to antiretroviral therapy.
Topics: Adolescent; Adult; Analysis of Variance; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Lamivudine; Lymphocyte Count; Male; Middle Aged; Sensitivity and Specificity; Time Factors; Zidovudine | 2001 |
A case of lipodystrophy after the initiation of zidovudine, lamivudine and efavirenz in an asymptomatic HIV-1-infected patient.
Topics: Abdomen; Adipose Tissue; Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Lipodystrophy; Male; Oxazines; Reverse Transcriptase Inhibitors; Tomography, X-Ray Computed; Zidovudine | 2000 |
Prediction of abacavir resistance from genotypic data: impact of zidovudine and lamivudine resistance in vitro and in vivo.
Topics: Algorithms; Anti-HIV Agents; Dideoxynucleosides; Drug Resistance, Microbial; Gene Frequency; Genotype; HIV; Humans; Lamivudine; Microbial Sensitivity Tests; Zidovudine | 2002 |
Summaries for patients. Predictors of outcomes in patients with HIV infection treated with indinavir, zidovudine, and lamivudine.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Protocols; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; RNA, Viral; Viral Load; Zidovudine | 2001 |
Prevalence and genetic heterogeneity of the reverse transcriptase T69S-S-X insertion in pretreated HIV-infected patients.
Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Viral; Genetic Heterogeneity; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Mutagenesis; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zidovudine | 2001 |
Complete remission of AIDS/Kaposi's sarcoma after treatment with a combination of two nucleoside reverse transcriptase inhibitors and one non-nucleoside reverse transcriptase inhibitor.
Topics: Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; HIV-1; Homosexuality, Male; Humans; Lamivudine; Male; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Sarcoma, Kaposi; Treatment Outcome; Viral Load; Zidovudine | 2002 |
Low-rate emergence of thymidine analogue mutations and multi-drug resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus lamivudine combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; Humans; Lamivudine; Mutation; Stavudine; Viral Load; Zidovudine | 2001 |
Clinical trials group: two studies are now open to patients who qualify.
Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Oxazines; Patient Selection; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Zidovudine | 2000 |
Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries.
Topics: Anti-HIV Agents; Developing Countries; Didanosine; Drug Resistance, Viral; Gabon; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Population Surveillance; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2002 |
Regression of HIV-associated pulmonary arterial hypertension and long-term survival during antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Anticoagulants; Drug Therapy, Combination; Echocardiography; Follow-Up Studies; HIV Infections; Humans; Hypertension, Pulmonary; Lamivudine; Male; Nelfinavir; Severity of Illness Index; Stavudine; Treatment Outcome; Zidovudine | 2001 |
Recurrent hypersensitivity to Combivir.
Topics: Adult; Anti-HIV Agents; Drug Combinations; Drug Hypersensitivity; Female; HIV Infections; HIV-1; Humans; Lamivudine; Recurrence; Zidovudine | 2002 |
Mycobacterium xenopi pulmonary infection in an HIV infected patient under highly active antiretroviral treatment.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Combinations; Female; Humans; Immunocompromised Host; Lamivudine; Lung Diseases; Mycobacterium Infections, Nontuberculous; Mycobacterium xenopi; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine | 2002 |
Parallel decline of CD8+/CD38++ T cells and viraemia in response to quadruple highly active antiretroviral therapy in primary HIV infection.
Topics: Adult; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Biomarkers; Carbamates; CD48 Antigen; CD8-Positive T-Lymphocytes; Dideoxynucleosides; Female; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphocyte Count; Male; Middle Aged; Reverse Transcriptase Inhibitors; Sulfonamides; T-Lymphocyte Subsets; Treatment Outcome; Viral Load; Viremia; Zidovudine | 2002 |
The pharmacokinetics of methadone following co-administration with a lamivudine/zidovudine combination tablet in opiate-dependent subjects.
Topics: Adolescent; Adult; Anti-HIV Agents; Drug Combinations; Female; HIV Seropositivity; Humans; Lamivudine; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Zidovudine | 2002 |
Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys.
Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; DNA; DNA Damage; Erythrocebus patas; Female; Fetus; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Maternal-Fetal Exchange; Placenta; Pregnancy; Reverse Transcriptase Inhibitors; Telomere; Zidovudine | 2002 |
Is AZT/3TC therapy effective against FIV infection or immunopathogenesis?
Topics: Animals; Anti-HIV Agents; Antibodies, Viral; Cat Diseases; Cats; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Synergism; Drug Therapy, Combination; Feline Acquired Immunodeficiency Syndrome; Flow Cytometry; Immunodeficiency Virus, Feline; Lamivudine; Random Allocation; Viral Load; Zidovudine | 2002 |
Switching to zidovudine plus lamivudine plus abacavir maintains viral suppression in patients with high viral load before antiretroviral therapy: a retrospective clinical cohort analysis.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Dideoxynucleosides; Drug Evaluation; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; London; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Viremia; Zidovudine | 2002 |
[Post-exposure prophylaxis in Zambia; the experiences of a tropical disease specialist following a cut accidentally incurred while operating on an HIV positive patient].
Topics: Adult; Anti-HIV Agents; Health Personnel; HIV Infections; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zambia; Zidovudine | 2002 |
DPC 817: a cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variants.
Topics: Animals; Anti-HIV Agents; Cytidine; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Macaca mulatta; Nucleosides; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine | 2002 |
The human 26S proteasome is a target of antiretroviral agents.
Topics: Anti-HIV Agents; DNA-Binding Proteins; Drug Delivery Systems; HIV Protease Inhibitors; Humans; I-kappa B Proteins; Indinavir; Jurkat Cells; Lamivudine; NF-kappa B; NF-KappaB Inhibitor alpha; Peptide Hydrolases; Proteasome Endopeptidase Complex; Reverse Transcriptase Inhibitors; Ubiquitin; Zidovudine | 2002 |
Improved long-term suppression of HIV-1 replication with a triple-class multidrug regimen compared with standard of care antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Follow-Up Studies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load; Virus Replication; Zidovudine | 2002 |
Genotypic drug resistance during HIV-1 primary infection in France (1996-1999): frequency and response to treatment.
Topics: Adult; Antiretroviral Therapy, Highly Active; Cohort Studies; Drug Resistance, Viral; Female; France; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Ritonavir; RNA, Viral; Viral Load; Zidovudine | 2002 |
[Drug combination therapy for children infected with HIV/AIDS--own experience].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Poland; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2001 |
Needlestick transmission of hepatitis C.
Topics: Accidents, Occupational; Acute Disease; Adult; Anti-HIV Agents; Antiviral Agents; Asthenia; Exanthema; Hepacivirus; Hepatitis C; Hepatitis C Antibodies; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Interferon alpha-2; Interferon-alpha; Internship and Residency; Lamivudine; Needlestick Injuries; Nelfinavir; Occupational Exposure; Physicians; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Viremia; Zidovudine | 2002 |
Delayed recovery of effector memory CD4+ T cells by highly active antiretroviral therapy in a patient with HIV-1 infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Immunologic Memory; Lamivudine; Lymphocyte Count; Male; Nelfinavir; Time Factors; Zidovudine | 2002 |
Normalization of liver enzymes in an HIV-hepatitis C virus-co-infected patient after potent antiretroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Alanine Transaminase; Alkynes; Anti-HIV Agents; Aspartate Aminotransferases; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Female; Hepatitis C; Humans; Lamivudine; Liver; Oxazines; RNA, Viral; Zidovudine | 2002 |
Determination of zidovudine/lamivudine/nevirapine in human plasma using ion-pair HPLC.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamivudine; Nevirapine; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Zidovudine | 2002 |
Pressure of zidovudine accelerates the reversion of lamivudine resistance-conferring M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1.
Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Virus Replication; Zidovudine | 2002 |
Transmission of drug-resistant HIV after an occupational exposure despite postexposure prophylaxis with a combination drug regimen.
Topics: Adult; Anti-HIV Agents; Health Personnel; HIV; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Needlestick Injuries; Occupational Exposure; Treatment Failure; Zidovudine | 2002 |
Human immunodeficiency virus 1 strains resistant to nucleoside inhibitors of reverse transcriptase in isolates from the Czech Republic as monitored by line probe assay and nucleotide sequencing.
Topics: Base Sequence; Codon; Czech Republic; Didanosine; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Probe Techniques; Molecular Sequence Data; Mutation; Phylogeny; Prevalence; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Zalcitabine; Zidovudine | 2001 |
Counterfit drugs: check Combivir, Serostim, Epogen.
Topics: Crime; Drug Combinations; Drug Labeling; Epoetin Alfa; Erythropoietin; Growth Hormone; Human Growth Hormone; Lamivudine; Recombinant Proteins; United States; United States Food and Drug Administration; Zidovudine | 2002 |
A case of flare syndrome.
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Indinavir; Lamivudine; Male; Organophosphonates; Organophosphorus Compounds; Zidovudine | 2001 |
Anti-HIV agents. Trizivir--three drugs in one pill.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Zidovudine | 2000 |
Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11.
Topics: Anti-HIV Agents; ATP-Binding Cassette Transporters; Biological Transport; Deoxycytidine Kinase; Drug Resistance, Multiple; HIV; Humans; Lamivudine; Multidrug Resistance-Associated Proteins; Nucleosides; T-Lymphocytes; Tumor Cells, Cultured; Zidovudine | 2002 |
Immunophenotypic analyses of CD34(+) cell subsets in bone marrow from HIV-infected patients during highly- active antiretroviral therapy.
Topics: Adult; Antigens, CD34; Antiretroviral Therapy, Highly Active; beta 2-Microglobulin; Bone Marrow Cells; Case-Control Studies; Female; Flow Cytometry; HIV Infections; HIV Protease Inhibitors; Humans; Immunoglobulin G; Immunophenotyping; Indinavir; Lamivudine; Leukocyte Count; Male; Middle Aged; Stavudine; T-Lymphocyte Subsets; Zidovudine | 2002 |
Antiretroviral rounds. Personal and public consequences.
Topics: Adult; Alcohol Drinking; Candidiasis, Oral; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Pneumonia, Bacterial; Sexual Partners; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Zidovudine | 2000 |
"Trizivir" approved: three existing drugs in one.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Approval; Drug Combinations; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine | 2000 |
Geotrichum proctitis after HIV postexposure prophylaxis.
Topics: Drug Therapy, Combination; Female; Geotrichosis; HIV Infections; Humans; Lamivudine; Middle Aged; Proctitis; Reverse Transcriptase Inhibitors; Zidovudine | 2002 |
HIV-1 infection in women.
Topics: CD4 Lymphocyte Count; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Male; Sexual Behavior; Sexually Transmitted Diseases; Thailand; Viral Load; Zidovudine | 2000 |
New drugs.
Topics: Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Approval; Drug Combinations; Humans; Lamivudine; Lopinavir; Pyrimidinones; Ritonavir; Zidovudine | 2001 |
Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies.
Topics: Animals; Anti-HIV Agents; COS Cells; Dose-Response Relationship, Drug; Drug Resistance, Viral; Genetic Vectors; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Thymidine; Virus Replication; Zidovudine | 2002 |
Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine.
Topics: Animals; Anti-HIV Agents; Bone Marrow; Bromodeoxyuridine; Drug Interactions; Drug Resistance, Neoplasm; Erythrocytes; Female; Gene Frequency; Hypoxanthine Phosphoribosyltransferase; Lamivudine; Loss of Heterozygosity; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronuclei, Chromosome-Defective; Mutation; Thymidine Kinase; Zidovudine | 2002 |
Prevalence of G333D/E in naive and pretreated HIV-infected patients.
Topics: Amino Acid Sequence; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 2002 |
Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Codon; Crystallization; Drug Resistance, Viral; HIV Reverse Transcriptase; Lamivudine; Mutation; Protein Conformation; Zidovudine | 2002 |
[Cytomegalovirus retinitis after highly active antiretroviral therapy: a case report].
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Didanosine; Ganciclovir; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Retinal Hemorrhage; Reverse Transcriptase Inhibitors; Risk; Saquinavir; Stavudine; Substance Abuse, Intravenous; Zidovudine | 2002 |
Highlights of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).
Topics: Adenine; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Drug Therapy; Epoetin Alfa; Erythropoietin; Hepatitis C; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Saquinavir; Tenofovir; Zidovudine | 2002 |
Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach.
Topics: Anti-HIV Agents; Binding Sites; Dioxolanes; Drug Resistance; Guanosine; HIV-1; Lamivudine; Models, Molecular; Mutation, Missense; Protein Binding; Purine Nucleosides; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Zidovudine | 2002 |
Development of a pharmacodynamic model for HIV treatment with nucleoside reverse transcriptase and protease inhibitors.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Statistical; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Viral Load; Zidovudine | 2002 |
Cost price drugs for developing countries are found in Belgian pharmacies.
Topics: Anti-HIV Agents; Belgium; Crime; Developing Countries; Drug Combinations; Humans; Lamivudine; Pharmacies; Zidovudine | 2002 |
Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors.
Topics: Amino Acid Sequence; Deoxycytidine Monophosphate; Diphosphates; DNA; DNA Primers; DNA Replication; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; Humans; Lamivudine; Molecular Sequence Data; Recombinant Proteins; Reverse Transcriptase Inhibitors; Sequence Alignment; Thymidine Monophosphate; Zalcitabine; Zidovudine | 2002 |
Metabolic activation of nucleoside and nucleotide reverse transcriptase inhibitors in dendritic and Langerhans cells.
Topics: Adenine; Anti-HIV Agents; Cell Line; Cells, Cultured; Dendritic Cells; Humans; Lamivudine; Langerhans Cells; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; T-Lymphocytes; Tenofovir; Zidovudine | 2002 |
[Factors predicting lack of adherence to highly active antiretroviral treatment].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Data Collection; Drug Combinations; Drug Utilization Review; HIV Infections; Humans; Lamivudine; Outpatient Clinics, Hospital; Patient Compliance; Patient Dropouts; Registries; Sensitivity and Specificity; Spain; Treatment Refusal; Zidovudine | 2002 |
Phenotypic and genotypic analysis of biologically cloned human immunodeficiency virus type 1 isolates from patients treated with zidovudine and lamivudine.
Topics: Clone Cells; Drug Resistance, Viral; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Zidovudine | 2002 |
Mean cell volume (MCV) changes in HIV-positive patients taking nucleoside reverse transcriptase inhibitors (NRTIs): a surrogate marker for adherence.
Topics: Biomarkers; Erythrocyte Indices; HIV Infections; Humans; Lamivudine; Patient Compliance; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 2002 |
High prevalence of genotypic resistance to nucleoside reverse transcriptase inhibitors among therapy-naive individuals from the Warsaw cohort.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Cohort Studies; Drug Resistance, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 2002 |
Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Mutation; Phenotype; RNA, Viral; Stavudine; Zidovudine | 2002 |
Therapeutic responses to AZT + 3TC + EFV in advanced antiretroviral naive HIV type 1-infected Ugandan patients.
Topics: Adult; Alkynes; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Patient Compliance; Reverse Transcriptase Inhibitors; Uganda; Viral Load; Zidovudine | 2002 |
Effect of co-formulated zidovudine, lamivudine and abacavir (Trizivir) on antiretroviral-naive patients presenting with advanced HIV-1 infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; Viral Load; Zidovudine | 2003 |
Indirect hyperbilirubinemia with indinavir.
Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hyperbilirubinemia; India; Indinavir; Lamivudine; Liver Function Tests; Needlestick Injuries; Prognosis; Risk Assessment; Severity of Illness Index; Zidovudine | 2002 |
Estimating the length of the first antiretroviral therapy regiment durability in São Paulo, Brazil.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brazil; Cohort Studies; Drug Administration Schedule; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Compliance; Retrospective Studies; Time Factors; Zidovudine | 2002 |
Multiple relapses of human cytomegalovirus retinitis during HAART in an AIDS patient with reconstitution of CD4+ T cell count in the absence of HCMV-specific CD4+ T cell response.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cytomegalovirus Retinitis; Didanosine; Follow-Up Studies; Ganciclovir; HIV Protease Inhibitors; Humans; Lamivudine; Lymphocyte Activation; Male; Nevirapine; Recurrence; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2003 |
HIV--a personal perspective.
Topics: Anti-HIV Agents; HIV Infections; Humans; Lamivudine; Needlestick Injuries; Zidovudine | 2000 |
Preventing HIV transmission.
Topics: Anti-HIV Agents; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Zidovudine | 2003 |
FDA notifications. Product tampering labels Ziagen as Combivir.
Topics: Acquired Immunodeficiency Syndrome; Dideoxynucleosides; Drug Combinations; Drug Labeling; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine | 2002 |
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
Topics: Acquired Immunodeficiency Syndrome; Cytidine Triphosphate; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Dideoxynucleotides; Dioxolanes; DNA, Viral; Drug Resistance, Viral; Guanosine; Guanosine Triphosphate; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 2003 |
Negligence. Liver transplant patient too late to sue Viramune maker.
Topics: Drug Combinations; Drug Industry; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Liver Failure; Liver Transplantation; Malpractice; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine | 2003 |
Abacavir arm stopped in clinical trial.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Viral Load; Zidovudine | 2003 |
AIDS drug in halted trial less effective as monotherapy.
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Humans; Lamivudine; Oxazines; Viral Load; Zidovudine | 2003 |
Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.
Topics: Amino Acid Sequence; Anti-HIV Agents; Baculoviridae; Binding Sites; DNA Polymerase gamma; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Electrophoretic Mobility Shift Assay; Humans; Lamivudine; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Stavudine; Zalcitabine; Zidovudine | 2003 |
[Measuring the HIV viral load with LCx (Abbott): importance for the therapeutic follow-up of 3 patients infected by type O HIV].
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Oxazines; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Viremia; Zidovudine | 2003 |
Management of severely immunocompromised human immunodeficiency virus type 1-infected African orphans with structured treatment interruption: another kind of salvage therapy.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Dideoxynucleosides; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Salvage Therapy; Zidovudine | 2003 |
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
Topics: Adenine; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Didanosine; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Transfection; Zalcitabine; Zidovudine | 2003 |
Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Base Sequence; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Resistance, Viral; HIV Reverse Transcriptase; Inhibitory Concentration 50; Kinetics; Lamivudine; Molecular Sequence Data; Mutation; Phenotype; Time Factors; Zidovudine | 2003 |
Selection of resistance mutations in pregnant women receiving zidovudine and lamivudine to prevent HIV perinatal transmission.
Topics: Anti-HIV Agents; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Pregnancy; Retrospective Studies; Zidovudine | 2003 |
Trizivir trial halted.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Zidovudine | 2003 |
[Observational study on the efficacy of the application of two classical regimens of triple antiretroviral therapy].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Didanosine; Drug Evaluation; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2003 |
Sequential cutaneous drug reactions to protease inhibitors in the context of occupational post-exposure prophylaxis.
Topics: Adult; Drug Hypersensitivity; Female; Guideline Adherence; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Needlestick Injuries; Occupational Diseases; Occupational Exposure; Zidovudine | 2003 |
[Opiates withdrawal syndrome after treatment with zidovudine + lamivudine + abcavir in patients with positivity for HIV and treated with methadone].
Topics: Adult; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Male; Methadone; Opioid-Related Disorders; Reverse Transcriptase Inhibitors; Substance Withdrawal Syndrome; Treatment Outcome; Zidovudine | 2003 |
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Cell Line; Dideoxynucleosides; Human T-lymphotropic virus 1; Humans; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zalcitabine; Zidovudine | 2003 |
Vertical transmission of HIV in Rio de Janeiro, Brazil.
Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; Brazil; Cohort Studies; Developing Countries; Female; HIV Infections; Humans; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Zidovudine | 2003 |
pol gene sequence variation in Swedish HIV-2 patients failing antiretroviral therapy.
Topics: Adolescent; Adult; Africa, Western; Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; Codon; Drug Resistance, Multiple, Viral; Evolution, Molecular; Female; Genes, pol; Genetic Variation; HIV Infections; HIV Protease Inhibitors; HIV-1; HIV-2; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Nelfinavir; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Sequence Alignment; Sequence Homology, Amino Acid; Sweden; Treatment Failure; Viremia; Zidovudine | 2003 |
[Antiviral agents for reduction of mother-to-child transmission of HIV infection].
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Evidence-Based Medicine; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Zidovudine | 2003 |
[Inhibitory effect of telomerase inhibitors combined with X-irradiation on bone marrow hematopoiesis in mice].
Topics: Animals; Bone Marrow; Enzyme Inhibitors; Female; Hematopoiesis; Lamivudine; Mice; Mice, Inbred BALB C; Telomerase; X-Rays; Zidovudine | 2003 |
AIDS foundation seeks withdrawal of approval for HIV drug combination.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Approval; Drug Combinations; Foundations; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine | 2003 |
[Hypersensitive reaction to abacavir or syphilitic hepatitis?].
Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Ethylenediamines; HIV Seropositivity; Humans; Lamivudine; Male; Syphilis; Zidovudine | 2003 |
Studies of molecular mechanism of tenofovir against 3TC- and AZT-resistance mutant HIV-1 reverse transcriptase.
Topics: Adenine; Amino Acid Sequence; Drug Resistance, Viral; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Mutagenesis, Site-Directed; Organophosphonates; Organophosphorus Compounds; Protein Conformation; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2003 |
Safety and efficacy of switching to alternative nucleoside analogues following symptomatic hyperlactatemia and lactic acidosis.
Topics: Acidosis, Lactic; Adult; Alanine Transaminase; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lactates; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Zidovudine | 2003 |
Liquid chromatographic-mass spectrometric determination of the metabolism and disposition of the anti-retroviral nucleoside analogs zidovudine and lamivudine in C57BL/6N and B6C3F1 mice.
Topics: Animals; Area Under Curve; Chromatography, Liquid; Female; Fetus; Lamivudine; Mass Spectrometry; Mice; Mice, Inbred Strains; Reproducibility of Results; Reverse Transcriptase Inhibitors; Zidovudine | 2003 |
AACTG A5095, Trizivir, and the role of all-nucleoside regimens: an editorial.
Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2003 |
Abandon Trizivir when it's working well? A rebuttal.
Topics: Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2003 |
GSK and Boehringer agree to generic AIDS drugs deal.
Topics: Acquired Immunodeficiency Syndrome; Africa South of the Sahara; Anti-Retroviral Agents; Commerce; Drug Industry; Drugs, Generic; Humans; Lamivudine; Legislation, Drug; South Africa; Zidovudine | 2003 |
Treatment of primary HIV-1 infection with nonnucleoside reverse transcriptase inhibitor-based therapy is effective and well tolerated.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4-CD8 Ratio; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Flow Cytometry; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Activation; Lymphocyte Subsets; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2004 |
HIVNET 012 and Petra.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine | 2004 |
Comment: Reasons for early abacavir discontinuation in HIV-infected patients.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Treatment Refusal; Zidovudine | 2004 |
Conference report - antiretroviral therapy update from the 9th European AIDS Conference.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Age Factors; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Botswana; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; HIV Infections; Humans; Lamivudine; Middle Aged; Pulse Therapy, Drug; Reverse Transcriptase Inhibitors; Salvage Therapy; Viral Load; Zidovudine | 2003 |
Efficacy and safety of ritonavir/indinavir 100/400 mg twice daily in combination with two nucleoside analogues in antiretroviral treatment-naive HIV-infected individuals.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Ritonavir; Stavudine; Zidovudine | 2003 |
Antiretroviral therapy influences cellular susceptibility to apoptosis in vivo.
Topics: Adult; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Apoptosis; Drug Combinations; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Zidovudine | 2004 |
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.
Topics: Cells, Cultured; Dideoxynucleotides; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Neutrophils; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate; Viral Plaque Assay; Zidovudine | 2004 |
Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid.
Topics: Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Interactions; Epilepsy, Complex Partial; HIV Infections; Humans; Lamivudine; Male; Valproic Acid; Zidovudine | 2004 |
Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine.
Topics: Animals; Anti-HIV Agents; Brain; DNA, Mitochondrial; Erythrocebus patas; Female; Fetus; Lamivudine; Maternal-Fetal Exchange; Microscopy, Electron; Mitochondria; Muscle, Skeletal; Myocardium; Organ Specificity; Placenta; Pregnancy; Reverse Transcriptase Inhibitors; Zidovudine | 2004 |
[Ensuring high adherence. Clever combination assures therapeutic success].
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Oxazines; Patient Compliance; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine | 2003 |
[Long-term tolerance. Preventing lipoatrophy].
Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Dideoxynucleosides; DNA, Mitochondrial; Drug Combinations; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Long-Term Care; Risk Factors; Stavudine; Zidovudine | 2003 |
Purifying selection masks the mutational flexibility of HIV-1 reverse transcriptase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Anti-Retroviral Agents; Cell Line; Cloning, Molecular; Conserved Sequence; DNA Mutational Analysis; Genetic Techniques; Genetic Variation; HeLa Cells; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Virus Replication; Zidovudine | 2004 |
Behavioral impact, acceptability, and HIV incidence among homosexual men with access to postexposure chemoprophylaxis for HIV.
Topics: Adult; Anti-HIV Agents; Brazil; Chemoprevention; Cohort Studies; HIV Infections; HIV Seropositivity; Homosexuality, Male; Humans; Lamivudine; Male; Patient Acceptance of Health Care; Sexual Behavior; Surveys and Questionnaires; Zidovudine | 2004 |
Comparison of generic zidovudine + lamivudine (Cipla, Duovir) and the GlaxoSmithKline brand (Combivir) tablets.
Topics: Chromatography, High Pressure Liquid; Costs and Cost Analysis; Drug Combinations; Drugs, Generic; HIV Infections; Humans; Lamivudine; Tablets; Zidovudine | 2004 |
Derivative-differential UV spectrophotometry and compensation technique for the simultaneous determination of zidovudine and lamivudine in human serum.
Topics: Adult; Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Drug Combinations; Humans; Lamivudine; Male; Reference Standards; Spectrophotometry, Ultraviolet; Tablets; Zidovudine | 2004 |
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Mitochondrial; Drug Combinations; Female; Fetal Blood; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Maternal-Fetal Exchange; Microscopy, Electron; Mitochondria; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Umbilical Cord; Zidovudine | 2004 |
Buffalo hump: what the experts suggest.
Topics: Adult; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Reverse Transcriptase Inhibitors; Zidovudine | 2004 |
Lamivudine 300 mg in HIV infection: dose change. Once-a-day dosing.
Topics: Adult; Child; Drug Therapy, Combination; France; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Protease Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Hemophagocytic syndrome as a presenting sign of transformation of smoldering to acute adult T-cell leukemia/lymphoma: efficacy of anti-retroviral and interferon therapy.
Topics: Antineoplastic Agents; Antiviral Agents; Drug Therapy, Combination; Female; Histiocytosis; Humans; Interferon-alpha; Lamivudine; Leukemia-Lymphoma, Adult T-Cell; Middle Aged; Zidovudine | 2004 |
[Antiretroviral therapy of acute HIV-infection].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Combinations; Female; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Lymphocyte Count; Male; Nevirapine; Viral Load; Zidovudine | 2004 |
Benefits of a rapid HIV test for evaluation of the source patient after occupational exposure of healthcare workers.
Topics: AIDS Serodiagnosis; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood-Borne Pathogens; Chemoprevention; Diagnostic Tests, Routine; Health Personnel; HIV Infections; Humans; Immunoenzyme Techniques; Infectious Disease Transmission, Patient-to-Professional; Italy; Lamivudine; Occupational Exposure; Pilot Projects; Zidovudine | 2004 |
WHO pulls two generic AIDS drugs from approved list.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Approval; Drugs, Generic; Formularies as Topic; Humans; Lamivudine; Therapeutic Equivalency; World Health Organization; Zidovudine | 2004 |
Mitochondrial damage revealed by morphometric and semiquantitative analysis of mouse pup cardiomyocytes following in utero and postnatal exposure to zidovudine and lamivudine.
Topics: Animals; Animals, Newborn; Anti-HIV Agents; Female; Lamivudine; Male; Mice; Microscopy, Electron; Mitochondria, Heart; Myocytes, Cardiac; Pregnancy; Zidovudine | 2004 |
Nucleoside analogue use before and during highly active antiretroviral therapy and virus load rebound.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; Cohort Studies; Didanosine; Drug Administration Schedule; Europe; Female; HIV Infections; Humans; Lamivudine; Male; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Viral Load; Zidovudine | 2004 |
Zidovudine, lamivudine, and abacavir have different effects on resting cells infected with human immunodeficiency virus in vitro.
Topics: Anti-HIV Agents; Cells, Cultured; Dideoxynucleosides; Drug Evaluation, Preclinical; HIV Core Protein p24; HIV Infections; Humans; Immunotoxins; Lamivudine; Phytohemagglutinins; Receptors, Interleukin-2; Reverse Transcriptase Inhibitors; Zidovudine | 2004 |
Triple-nucleoside regimens versus efavirenz.
Topics: Alkynes; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Oxazines; Research Design; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2004 |
Triple-nucleoside regimens versus efavirenz.
Topics: Alkynes; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Oxazines; Patient Compliance; Reverse Transcriptase Inhibitors; Zidovudine | 2004 |
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.
Topics: Age Factors; Animals; Animals, Newborn; Anti-HIV Agents; Body Weight; Cardiomyopathies; DNA, Mitochondrial; Drug Interactions; Electrocardiography; Electron Transport Complex IV; Female; Lamivudine; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mutation; Myocardium; Organ Size; Pilot Projects; Pregnancy; Sex Factors; Zidovudine | 2004 |
Simultaneous determination of zidovudine and lamivudine from rat plasma, amniotic fluid and tissues by HPLC.
Topics: Amniotic Fluid; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Female; Fetus; Half-Life; Lamivudine; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Tissue Distribution; Zidovudine | 2004 |
Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy.
Topics: Abnormalities, Drug-Induced; Anti-Retroviral Agents; Female; Gestational Age; Humans; Lamivudine; Maternal-Fetal Exchange; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Stavudine; Zidovudine | 2004 |
Perinatal HIV research unit clarifies nevirapine resistance and transmission issues.
Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Zidovudine | 2004 |
Tenofovir: new indication. For first-line antiretroviral therapy: wait and see.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine | 2004 |
Antiretroviral treatment. HIV infection in adults: better-defined first-line treatment.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Oligopeptides; Organophosphonates; Oxazines; Pregnancy; Pyrimidinones; Ritonavir; Stavudine; Sulfonamides; Treatment Outcome; Viral Load; Zidovudine | 2004 |
[Simplified treatments for HIV infection].
Topics: Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Switzerland; Time Factors; Treatment Outcome; Zidovudine | 2004 |
Effect of concurrent zidovudine use on the resistance pathway selected by abacavir-containing regimens.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Genes, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Point Mutation; Retrospective Studies; Reverse Transcriptase Inhibitors; Zidovudine | 2004 |
Pilot studies of single and combination antiretroviral therapy in patients with primary biliary cirrhosis.
Topics: Adult; Aged; Analysis of Variance; Drug Combinations; Female; Humans; Lamivudine; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Pilot Projects; Retroviridae Infections; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine | 2004 |
Proof of principal studies to assess the role of the human betaretrovirus in patients with primary biliary cirrhosis.
Topics: Autoimmune Diseases; Drug Combinations; Humans; Lamivudine; Liver Cirrhosis, Biliary; Retroviridae Infections; Zidovudine | 2004 |
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine | 2004 |
Long-term efficacy after switch from protease inhibitor-containing highly active antiretroviral therapy to abacavir, lamivudine, and zidovudine.
Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Time Factors; Treatment Failure; Zidovudine | 2004 |
Response to the comparison of generic zidovudine plus lamivudine (Cipla, Duovir) and the GlaxoSmithKline brand (Combivir) tablets.
Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Generic; HIV Infections; Humans; Lamivudine; Tablets; Zidovudine | 2004 |
Fatal inflammatory AIDS-associated PML with high CD4 counts on HAART: a new clinical entity?
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; CD4 Lymphocyte Count; Cidofovir; Cytosine; Dideoxynucleosides; Encephalitis; False Negative Reactions; Fatal Outcome; Humans; Immunocompromised Host; Indinavir; JC Virus; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Substance Abuse, Intravenous; Time Factors; Virus Activation; Zidovudine | 2004 |
Emergence of antiretroviral resistance in HIV-positive women receiving combination antiretroviral therapy in pregnancy.
Topics: Adolescent; Adult; Anti-HIV Agents; Base Sequence; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine | 2005 |
Low rate of treatment failure on antiretroviral therapy with tenofovir, lamivudine and zidovudine.
Topics: Adenine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Failure; Zidovudine | 2005 |
Effects of prenatal exposure to Zidovudine and Lamivudine on brainstem auditory evoked potentials in infants from HIV-infected women.
Topics: Adult; Anti-HIV Agents; Apgar Score; Evoked Potentials, Auditory, Brain Stem; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Zidovudine | 2004 |
Two AIDS medicines back on WHO prequalification list.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Approval; Drugs, Generic; Humans; Lamivudine; Therapeutic Equivalency; World Health Organization; Zidovudine | 2004 |
[Simplification to lamivudine, zidovudine, and abacavir therapy: impact on adherence, clinical outcome, and economic issues].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Costs and Cost Analysis; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Patient Compliance; Retrospective Studies; Zidovudine | 2004 |
Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Drug Stability; HIV; HIV Infections; Humans; Lamivudine; Quality Control; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine | 2005 |
Inhibitory drug levels found in breast milk.
Topics: Anti-Retroviral Agents; Female; HIV Infections; Humans; Infant; Lamivudine; Milk, Human; Nevirapine; Zidovudine | 2004 |
HIV/AIDS following sexual assault in Jamaican children and adolescents: a case for HIV post-exposure prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; Chemoprevention; Child; Child Abuse, Sexual; Drug Therapy, Combination; Female; HIV Infections; Humans; Jamaica; Lamivudine; Male; Rape; Risk Factors; Zidovudine | 2004 |
Simultaneous determination of zidovudine and lamivudine from rat tissues by liquid chromatography/tandem mass spectrometry.
Topics: Amniotic Fluid; Animals; Anti-HIV Agents; Drug Therapy, Combination; Female; Fetus; Injections, Intravenous; Lamivudine; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution; Zidovudine | 2005 |
AIDS treatment. A step toward cheaper anti-HIV therapy.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Developing Countries; Drug Approval; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Humans; Lamivudine; Nevirapine; United States; United States Food and Drug Administration; World Health Organization; Zidovudine | 2005 |
Top stories of 2004. ACTG 5095: efavirenz beats AZT + 3TC + abacavir.
Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Humans; Lamivudine; Oxazines; Viral Load; Zidovudine | 2005 |
Meeting notes from ICAAC. Tenofovir + emtricitabine vs. AZT + 3TC.
Topics: Adenine; CD4 Lymphocyte Count; Deoxycytidine; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Zidovudine | 2005 |
Meeting notes from ICAAC. NRTI-only regimens: making a comeback?
Topics: Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine | 2005 |
Field efficacy of zidovudine, lamivudine and single-dose nevirapine to prevent peripartum HIV transmission.
Topics: Adult; Anti-HIV Agents; Cote d'Ivoire; Developing Countries; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2005 |
Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells.
Topics: Anti-HIV Agents; Base Sequence; Cell Cycle; DNA; DNA Adducts; Gene Expression; HeLa Cells; Humans; Lamivudine; Mutagens; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; S Phase; Zidovudine | 2005 |
Postexposure prophylaxis after sexual assaults: a prospective cohort study.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Brazil; Child; Child, Preschool; Cohort Studies; Drug Administration Schedule; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Compliance; Prospective Studies; Rape; Sexually Transmitted Diseases; Zidovudine | 2005 |
Rapid viral load suppression following generic highly active antiretroviral therapy in Southern Indian HIV-infected patients.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drugs, Generic; Female; HIV Infections; HIV-1; Humans; India; Lamivudine; Male; Middle Aged; Oxazines; Prospective Studies; Tablets; Treatment Outcome; Viral Load; Zidovudine | 2005 |
[Meningeal cryptococcosis as a sign of immune reconstitution syndrome].
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Fluconazole; Flucytosine; HIV Infections; Humans; Immunologic Memory; Lamivudine; Lopinavir; Male; Meningitis, Cryptococcal; Pyrimidinones; Recurrence; Ritonavir; Syndrome; T-Lymphocyte Subsets; Zidovudine | 2005 |
Copackaged drug regimen approved for PEPFAR.
Topics: Adult; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine | 2005 |
Highly active antiretroviral therapy and human immunodeficiency virus encephalitis.
Topics: AIDS Dementia Complex; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Disease Models, Animal; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Viral Load; Zidovudine | 2005 |
Switching from protease inhibitors to a single-class regimen of abacavir/lamivudine/zidovudine plus tenofovir in patients with HIV load suppression.
Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Zidovudine | 2005 |
The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV post-exposure prophylaxis.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chi-Square Distribution; HIV Infections; Humans; Lamivudine; Male; Nelfinavir; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Assessment; Risk-Taking; Stavudine; Tenofovir; Zidovudine | 2005 |
Recurrence of post-traumatic stress disorder and antiretrovirals.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4-Positive T-Lymphocytes; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Oxazines; Recurrence; RNA, Viral; Stress Disorders, Post-Traumatic; Viral Load; Zidovudine | 2005 |
In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Combinations; Drug Interactions; HIV-1; Humans; Lamivudine; Least-Squares Analysis; Models, Theoretical; Nelfinavir; Nevirapine; Phenotype; Stavudine; Thymidine Monophosphate; Virus Replication; Zidovudine | 2005 |
Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cholesterol; Dideoxynucleosides; Drug Combinations; Erythrocyte Indices; Humans; Lamivudine; Organophosphonates; Patient Compliance; Salvage Therapy; Tenofovir; Viral Load; Viremia; Zidovudine | 2005 |
Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001.
Topics: Adolescent; Adult; Anti-HIV Agents; Brazil; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Risk Factors; Viral Load; Zidovudine | 2005 |
Effect of antiretroviral drugs on maternal CD4 lymphocyte counts, HIV-1 RNA levels, and anthropometric parameters of their neonates.
Topics: Adolescent; Adult; Anti-HIV Agents; Birth Weight; Case-Control Studies; CD4 Lymphocyte Count; Female; Fetal Development; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA, Viral; Zidovudine | 2005 |
Simultaneous determination of HIV-protease inhibitors lamivudine and zidovudine in pharmaceutical formulations by micellar electrokinetic chromatography.
Topics: 4-Aminobenzoic Acid; Borates; Boric Acids; Buffers; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis; HIV Protease Inhibitors; Hydrogen-Ion Concentration; Kinetics; Lamivudine; Micelles; Models, Chemical; Pharmaceutical Preparations; Pressure; Reproducibility of Results; Sodium Dodecyl Sulfate; Solvents; Time Factors; Zidovudine | 2005 |
Lack of resistant mutation development after receiving short-course zidovudine plus lamivudine to prevent mother-to-child transmission.
Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 2005 |
Genital HIV-1 viral load is correlated with blood plasma HIV-1 viral load in Brazilian women and is reduced by antiretroviral therapy.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Brazil; Cervix Uteri; Cross-Sectional Studies; Cyclopropanes; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Nelfinavir; Prevalence; Time Factors; Vagina; Viral Load; Zidovudine | 2006 |
Antiretroviral therapy--alternative uses.
Topics: Anti-Retroviral Agents; Breast; Cosmetic Techniques; Drug Combinations; Drug Resistance, Viral; Female; HIV Infections; Humans; Lamivudine; Zidovudine | 2005 |
The effect of long-term storage on measured plasma lactate concentrations and prospective lactate results from a multicenter trial of antiretroviral therapy.
Topics: Acidosis, Lactic; Anti-HIV Agents; Blood Preservation; Blood Specimen Collection; Didanosine; HIV Infections; Humans; Lactates; Lamivudine; Multicenter Studies as Topic; Oxalates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Sodium Fluoride; Specimen Handling; Stavudine; Time Factors; Zidovudine | 2005 |
Adherence to combined Lamivudine + Zidovudine versus individual components: a community-based retrospective medicaid claims analysis.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Epidemiologic Methods; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Medicaid; Middle Aged; Patient Compliance; Zidovudine | 2005 |
Case records of the Massachusetts General Hospital. Case 32-2005. A 34-year-old HIV-positive woman who desired to become pregnant.
Topics: Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Cesarean Section; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Seropositivity; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Papillomaviridae; Papillomavirus Infections; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Uterine Cervicitis; Viral Load; Zidovudine | 2005 |
Life-threatening maternal and fetal macrocytic anemia from antiretroviral therapy.
Topics: Adult; Anemia, Macrocytic; Anti-HIV Agents; Cesarean Section; Drug Therapy, Combination; Female; Fetal Diseases; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Complications, Infectious; Pregnancy Outcome; Viral Load; Zidovudine | 2005 |
Triple nucleoside reverse transcriptase inhibitor- vs. nonnucleoside reverse transcriptase inhibitor-containing regimens as first-line therapy: efficacy and durability in a prospective cohort of French HIV-infected patients.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine | 2005 |
Mass needle stick injury in children from the Western cape.
Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Communicable Disease Control; Environmental Exposure; Hepatitis B; Hepatitis B Vaccines; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Medical Waste; Needlestick Injuries; South Africa; Treatment Outcome; Zidovudine | 2006 |
Hypertriglyceridemia and hypercholesterolemia in human immunodeficiency virus-1-infected children treated with protease inhibitors.
Topics: Adolescent; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Hypertriglyceridemia; Infant; Lamivudine; Male; Ritonavir; Saquinavir; Zidovudine | 2006 |
Bleomycin has antiviral properties against drug-resistant HIV strains and sensitises virus to currently used antiviral agents.
Topics: Anti-HIV Agents; Bleomycin; Cells, Cultured; Drug Resistance, Viral; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Mutation; Zidovudine | 2006 |
[Detection of HIV infection in pregnant women by rapid testing: a successful strategy to reduce its vertical transmission].
Topics: Adolescent; Adult; Anti-HIV Agents; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; HIV Antibodies; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Middle Aged; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prevalence; Uruguay; Zidovudine | 2005 |
Frequency of drug-resistant variants of HIV-1 coexistent with wild-type in treatment-naive patients of India.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; Genes, pol; HIV Infections; HIV-1; Humans; India; Infant; Lamivudine; Male; Middle Aged; Mutation; Zidovudine | 2005 |
Cytokine profiles in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy.
Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Child; Clinical Trials as Topic; Cytokines; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prognosis; Treatment Outcome; Zidovudine | 2005 |
In vitro mutagenicity studies of the antiretrovirals AZT, Didanosine, and 3TC and a plant antiviral extract Secomet-V derived from the Trifollium species.
Topics: Anti-HIV Agents; Antiviral Agents; Didanosine; Lamivudine; Mutagenicity Tests; Phytotherapy; Plant Extracts; Salmonella; Trifolium; Zidovudine | 2005 |
Effectiveness and safety of abacavir, lamivudine, and zidovudine in antiretroviral therapy-naive HIV-infected patients: results from a large multicenter observational cohort.
Topics: Adult; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Hypersensitivity; Lamivudine; Male; Patient Compliance; Retrospective Studies; Spain; Treatment Failure; Zidovudine | 2006 |
Low risk of nevirapine resistance mutations in the prevention of mother-to-child transmission of HIV-1: Agence Nationale de Recherches sur le SIDA Ditrame Plus, Abidjan, Cote d'Ivoire.
Topics: Cote d'Ivoire; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mothers; Mutation; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2006 |
[HIV infection presenting with bilateral optic neuropathy].
Topics: AIDS Serodiagnosis; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Disease Progression; Drug Therapy, Combination; Evoked Potentials, Visual; Facial Nerve Diseases; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Ischemia; Lamivudine; Lopinavir; Male; Meningitis, Viral; Methylprednisolone; Middle Aged; Optic Disk; Optic Nerve Diseases; Polyradiculopathy; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Visual Fields; Zidovudine | 2006 |
Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.
Topics: Animals; DNA; DNA, Mitochondrial; Echocardiography; Genes, pol; HIV Infections; HIV-1; Humans; Immunoblotting; Lamivudine; Membrane Transport Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Models, Molecular; Myocardium; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Stavudine; Zidovudine | 2006 |
Virological response to HIV-1 nucleoside/nucleotide reverse transcriptase inhibitors-based, tenofovir DF-including regimens in the ANRS Aquitaine Cohort.
Topics: Adenine; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; France; HIV Infections; HIV Reverse Transcriptase; HIV-1; Hospitals, University; Humans; Lamivudine; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2006 |
Unrecognized near-fatal hyperlactatemia in an HIV-infected infant exposed to nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Lactates; Lamivudine; Male; Mitochondria; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2007 |
Exposure to HIV and antiretroviral medication as a potential cause of necrotizing enterocolitis in term neonates.
Topics: Anti-HIV Agents; Enterocolitis, Necrotizing; HIV Seropositivity; Humans; Infant, Newborn; Lamivudine; Male; Nevirapine; Risk Factors; Zidovudine | 2006 |
Lung cancer as an immune reconstitution disease in an HIV-1 positive man receiving HAART.
Topics: Adult; Antiretroviral Therapy, Highly Active; Carcinoma, Small Cell; Fatal Outcome; HIV Seropositivity; Humans; Lamivudine; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Ritonavir; Saquinavir; Zidovudine | 2006 |
Relationship between antiretrovirals used as part of a cART regimen and CD4 cell count increases in patients with suppressed viremia.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Viremia; Zidovudine | 2006 |
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
Topics: Adenine; Anti-Retroviral Agents; Bias; Data Interpretation, Statistical; Deoxycytidine; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Research Design; Tenofovir; Zidovudine | 2006 |
Electronic chip fights counterfeiting.
Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Drug Industry; Drug Labeling; Electronics; Fraud; HIV Infections; Humans; Lamivudine; United States; Zidovudine | 2006 |
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
Topics: Adenine; Bone Density; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2006 |
Virological and immunological response to Combivir and emergence of drug resistance mutations in a cohort of HIV-2 patients in The Gambia.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Drug Resistance, Viral; HIV Infections; HIV-2; Humans; Lamivudine; Mutation; Viral Load; Zidovudine | 2006 |
Rapid improvement of liver function in a patient with HIV and hepatitis B coinfection treated with lamivudine and tenofovir.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; Hepatitis; HIV Infections; Humans; Lamivudine; Liver Function Tests; Organophosphonates; Tenofovir; Zidovudine | 2006 |
Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion.
Topics: Acute Disease; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; Follow-Up Studies; Histocompatibility Testing; HIV Seropositivity; HIV-1; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Retrospective Studies; RNA, Viral; Stavudine; Treatment Outcome; Zidovudine | 2006 |
Mitochondrial dysfunction following perinatal exposure to nucleoside analogues.
Topics: Anti-HIV Agents; Child; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Mitochondrial Diseases; Nervous System Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine | 2006 |
[Adherence, pharmacokinetic "tolerance capacity" and HIV resistance development].
Topics: Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Diagnosis, Differential; DNA Mutational Analysis; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Treatment Refusal; Viral Load; Zidovudine | 2006 |
Effect of nanoparticulate polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate on the permeability of zidovudine and lamivudine across the in vitro blood-brain barrier.
Topics: Animals; Anti-HIV Agents; Blood-Brain Barrier; Cattle; Cells, Cultured; Drug Carriers; Enbucrilate; Endothelial Cells; Ethanol; Lamivudine; Methacrylates; Nanoparticles; Particle Size; Permeability; Zidovudine | 2006 |
Long-term safety and tolerability of the lamivudine/abacavir combination as components of highly active antiretroviral therapy.
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Controlled Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Oxazines; Prospective Studies; Time Factors; Treatment Outcome; Zidovudine | 2006 |
[Pneumocystis jirovecii pneumonia: an old disease with a new name].
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents, Urinary; Antifungal Agents; Drug Combinations; Drug Therapy, Combination; Female; Fluconazole; Folic Acid Antagonists; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Middle Aged; Pneumocystis carinii; Pneumonia, Pneumocystis; Radiography, Thoracic; Trimethoprim; Zidovudine | 2006 |
Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis.
Topics: AIDS Dementia Complex; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cells, Cultured; Drug Delivery Systems; Excipients; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Macrophages; Mice; Mice, SCID; Nelfinavir; Poloxalene; Virus Replication; Zidovudine | 2007 |
The effects of prolonged treatment with zidovudine, lamivudine, and abacavir on a T-lymphoblastoid cell line.
Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Deoxycytidine Kinase; Dideoxynucleosides; Drug Resistance, Neoplasm; Humans; Lamivudine; Leukemia, Lymphoid; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; T-Lymphocytes; Thymidine Kinase; Zidovudine | 2006 |
Diminished selection for thymidine-analog mutations associated with the presence of M184V in Ethiopian children infected with HIV subtype C receiving lamivudine-containing therapy.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Inhibitory Concentration 50; Lamivudine; Male; Microbial Sensitivity Tests; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Selection, Genetic; Thymidine; Virus Replication; Zidovudine | 2006 |
Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleosides; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Genotype; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lysine; Mutagenesis, Site-Directed; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; Tenofovir; Thymine Nucleotides; Zidovudine | 2007 |
[Effects of traditional Chinese medicine on CD4 + T cell counts and HIV viral loads during structured treatment interruption in highly active antiretroviral therapy].
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Phytotherapy; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2006 |
Weight and body shape changes in a treatment-naive population after 6 months of nevirapine-based generic highly active antiretroviral therapy in South India.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Body Weight; CD4 Lymphocyte Count; Cohort Studies; Female; HIV Infections; Humans; India; Lamivudine; Male; Nevirapine; Stavudine; Zidovudine | 2007 |
Transcriptional profiling for understanding the basis of mitochondrial involvement in disease and toxicity using the mitochondria-specific MitoChip.
Topics: Animals; Disease Progression; DNA, Mitochondrial; Female; Gene Expression Profiling; Lamivudine; Mice; Mitochondria; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Inhibitors; Zidovudine | 2007 |
Human oral drugs absorption is correlated to their in vitro uptake by brush border membrane vesicles.
Topics: Acetaminophen; Administration, Oral; Animals; Azlocillin; Biological Transport, Active; Cefadroxil; Doxorubicin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Lamivudine; Mannitol; Osmolar Concentration; Ouabain; Pharmaceutical Preparations; Pharmacokinetics; Phenolsulfonphthalein; Rabbits; Zidovudine | 2007 |
Report from the XVI International AIDS Conference. Efavirenz for high viral load and low CD4--a secondary analysis of ACTG 5095.
Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2006 |
Simultaneous measurement of intracellular triphosphate metabolites of zidovudine, lamivudine and abacavir (carbovir) in human peripheral blood mononuclear cells by combined anion exchange solid phase extraction and LC-MS/MS.
Topics: Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Phosphates; Reference Standards; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Zidovudine | 2007 |
Painless periungual pyogenic granulomata associated with reverse transcriptase inhibitor therapy in a patient with human immunodeficiency virus infection.
Topics: Anti-HIV Agents; Drug Combinations; Granuloma, Pyogenic; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nail Diseases; Reverse Transcriptase Inhibitors; Zidovudine | 2007 |
Persistence of lamivudine-sensitive HIV-1 quasispecies in the presence of lamivudine in vitro and in vivo.
Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Kinetics; Lamivudine; Mutation; Retrospective Studies; RNA, Viral; T-Lymphocytes; Time Factors; Viral Load; Virus Replication; Zidovudine | 2007 |
Anti-HIV agents. Abacavir--as good as AZT?
Topics: Adult; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2003 |
Anti-HIV agents. Low rate of early virologic failure seen with a combination of Trizivir and tenofovir.
Topics: Adenine; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Organophosphonates; Tenofovir; Viral Load; Zidovudine | 2004 |
Plasma lopinavir trough levels in a group of pregnant women on lopinavir, ritonavir, zidovudine, and lamivudine.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Pyrimidinones; Ritonavir; Viral Load; Zidovudine | 2007 |
Less sensitive HIV-1 enzyme immunoassay as an adjuvant method for monitoring patients receiving antiretroviral therapy.
Topics: Anti-HIV Agents; Drug Monitoring; HIV Infections; HIV-1; Immunoenzyme Techniques; Indinavir; Lamivudine; Sensitivity and Specificity; Time Factors; Virus Replication; Zidovudine | 2007 |
Evaluating the utility of ion mobility separation in combination with high-pressure liquid chromatography/mass spectrometry to facilitate detection of trace impurities in formulated drug products.
Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Combinations; Drug Contamination; Drug Evaluation, Preclinical; Lamivudine; Microchemistry; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Technology, Pharmaceutical; Zidovudine | 2007 |
[Vitiligo in a black patient associated with HIV infection and repigmentation under antiretroviral therapy].
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Lamivudine; Nevirapine; Treatment Outcome; Vitiligo; Zidovudine | 2007 |
Nevirapine clearance from plasma in African adults stopping therapy: a pharmacokinetic substudy.
Topics: Adult; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Uganda; Zidovudine; Zimbabwe | 2007 |
Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells.
Topics: Adenine; Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Erythrocytes; HIV Infections; Humans; Lamivudine; Nucleosides; Organophosphonates; Phosphorylation; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Zidovudine | 2007 |
Thyrotoxic periodic paralysis in a Polynesian male following highly active antiretroviral therapy for HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Autoimmunity; Diarrhea; Drug Combinations; Genetic Predisposition to Disease; Graves Disease; Hawaii; Humans; Hypokalemic Periodic Paralysis; Iodine Radioisotopes; Lamivudine; Lopinavir; Male; Native Hawaiian or Other Pacific Islander; Polynesia; Pyrimidinones; Thyrotoxicosis; Zidovudine | 2007 |
Hypogonadism in HIV-1-infected men is common and does not resolve during antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Follicle Stimulating Hormone; HIV Infections; HIV-1; Humans; Hypogonadism; Lamivudine; Luteinizing Hormone; Male; Prevalence; Reverse Transcriptase Inhibitors; RNA, Viral; Switzerland; Testosterone; Time Factors; Treatment Outcome; Viral Load; Zidovudine | 2007 |
Evolution of resistance mutations during low-level viral replication in HIV-1-infected patients treated with zidovudine/lamivudine/abacavir as a first-line regimen.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cohort Studies; Dideoxynucleosides; DNA, Viral; Drug Combinations; Drug Monitoring; Drug Resistance, Viral; Follow-Up Studies; Genotype; Germany; HIV Infections; HIV-1; Humans; Lamivudine; Methionine; Mutation; Reverse Transcriptase Inhibitors; Thymidine; Time Factors; Treatment Failure; Valine; Viral Load; Virus Replication; Zidovudine | 2007 |
Assessment of adverse events associated with antiretroviral regimens for postexposure prophylaxis for occupational and nonoccupational exposures to prevent transmission of human immunodeficiency virus.
Topics: Adenine; Adult; Anti-HIV Agents; Chemoprevention; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Middle Aged; New York; Occupational Exposure; Occupational Health Services; Organophosphonates; Patient Compliance; Public Health Administration; Retrospective Studies; Risk Factors; Sex Factors; Student Health Services; Tenofovir; Universities; Zidovudine | 2007 |
Development of mitochondria-specific mouse oligonucleotide microarray and validation of data by real-time PCR.
Topics: Animals; Female; Gene Expression Profiling; Lamivudine; Male; Mice; Mitochondria; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Zidovudine | 2007 |
The HBV drug entecavir - effects on HIV-1 replication and resistance.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Phylogeny; Reverse Transcriptase Inhibitors; Reverse Transcription; RNA, Viral; Virus Replication; Zidovudine | 2007 |
Long-term foscarnet therapy remodels thymidine analogue mutations and alters resistance to zidovudine and lamivudine in HIV-1.
Topics: Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Evolution, Molecular; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Point Mutation; Reverse Transcriptase Inhibitors; Species Specificity; Thymidine; Time Factors; Zidovudine | 2007 |
HPV oral infection. Case report of an HIV-positive Nigerian sex worker.
Topics: Adenine; Adult; Alphapapillomavirus; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Female; HIV Infections; Humans; Italy; Lamivudine; Lopinavir; Mouth Mucosa; Nigeria; Organophosphonates; Papillomavirus Infections; Pyrimidinones; Ritonavir; Sex Work; Stomatitis; Tenofovir; Treatment Refusal; Zidovudine | 2007 |
Rapid and simple liquid chromatography tandem mass spectrometry method for the quantification of zidovudine in rat plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Injections, Intravenous; Lamivudine; Methanol; Rats; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Water; Zidovudine | 2008 |
Antiretroviral agents and acid-base balance at delivery of the neonate.
Topics: Acid-Base Equilibrium; Adult; Anti-HIV Agents; Case-Control Studies; Drug Therapy, Combination; Female; Fetal Blood; HIV Infections; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Outcome; Prospective Studies; Zidovudine | 2007 |
Comparison of the effectiveness of initial combined antiretroviral therapy with nelfinavir or efavirenz at a university-based outpatient service in Brazil.
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Clinical Protocols; Cohort Studies; Cyclopropanes; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Retrospective Studies; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine | 2007 |
Development of a highly efficient extraction technique and specific multiplex assay for measuring antiretroviral drug concentrations in breast milk.
Topics: Chromatography, High Pressure Liquid; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Nevirapine; Postpartum Period; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine | 2007 |
Effects of antiretroviral agents during pregnancy on liver enzymes and amylase in HIV-exposed, uninfected newborn infants.
Topics: Adolescent; Adult; Amylases; Anti-HIV Agents; Cohort Studies; Control Groups; Drug Therapy, Combination; Female; Fetal Blood; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Liver; Male; Nelfinavir; Pregnancy; Prospective Studies; Transaminases; Zidovudine | 2007 |
[Update on HIV infection in Mayotte].
Topics: Adult; Anti-HIV Agents; Comoros; Dideoxynucleosides; Drug Combinations; Female; Heterosexuality; HIV Infections; HIV Seropositivity; Homosexuality; Humans; Lamivudine; Male; Middle Aged; Transfusion Reaction; Viremia; Zidovudine | 2007 |
Prednisolone mediated suppression of HIV-1 viral load strongly correlates with C-C chemokine CCL2: In vivo and in vitro findings.
Topics: Alkynes; Anti-HIV Agents; Anti-Inflammatory Agents; Benzoxazines; Chemokine CCL2; Cyclopropanes; Drug Resistance, Viral; Flow Cytometry; Gene Expression; HIV Infections; HIV-1; Humans; In Vitro Techniques; Interleukin-8; Lamivudine; Male; Prednisolone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Uveitis; Viral Load; Viremia; Zidovudine | 2007 |
Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; CD4 Lymphocyte Count; Cohort Studies; Cote d'Ivoire; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Program Evaluation; Puerperal Disorders; Viral Load; Zidovudine | 2007 |
Concentrations of zidovudine- and lamivudine-triphosphate according to cell type in HIV-seronegative adults.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytidine Triphosphate; Dideoxynucleotides; Drug Administration Schedule; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine | 2007 |
Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis.
Topics: Adenine; Administration, Oral; Adult; Alkynes; Anti-Retroviral Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; Genitalia, Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2007 |
Early virological response of zidovudine/lamivudine/abacavir for patients co-infected with HIV and tuberculosis in Uganda.
Topics: Adult; Antitubercular Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Neutropenia; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Tuberculosis, Pulmonary; Zidovudine | 2007 |
First use of tamoxifen in an HIV patient with encapsulating peritoneal sclerosis.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Estrogen Antagonists; Glucocorticoids; HIV Infections; Humans; Kidney Failure, Chronic; Lamivudine; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneal Diseases; Saquinavir; Sclerosis; Tamoxifen; Zidovudine | 2007 |
Human immunodeficiency virus infection in a child presenting as herpes zoster ophthalmicus.
Topics: Acyclovir; Child; Eye Diseases; Herpes Zoster Ophthalmicus; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Zidovudine | 2007 |
Efficacy of highly active antiretroviral therapy in HIV-1 infected children in Kenya.
Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Weight; CD4 Lymphocyte Count; Child; Child, Preschool; Drugs, Generic; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Kenya; Lamivudine; Male; Nevirapine; Prospective Studies; RNA, Viral; Viral Load; Zidovudine | 2007 |
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zidovudine | 2007 |
[Rapid development of anemia in a HIV-positive patient with alpha-thalassemia after zidovudine therapy].
Topics: Adult; alpha-Thalassemia; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Diagnosis, Differential; Folic Acid; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Zidovudine | 2007 |
Metabolism and pharmacokinetics of the combination Zidovudine plus Lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis.
Topics: Animals; Anti-HIV Agents; Area Under Curve; Chromatography, Liquid; Drug Combinations; Erythrocebus patas; Half-Life; Lamivudine; Metabolic Clearance Rate; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Zidovudine | 2008 |
Non-occupational post exposure prophylaxis as a biobehavioral HIV-prevention intervention.
Topics: Adult; Anti-HIV Agents; Attitude to Health; Drug Combinations; Feasibility Studies; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Risk-Taking; Treatment Outcome; Zidovudine | 2008 |
Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.
Topics: Anti-HIV Agents; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lamivudine; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors; Thermodynamics; Zidovudine | 2008 |
Liver enzymes elevation and immune reconstitution among treatment-naïve HIV-infected patients instituting antiretroviral therapy.
Topics: Adult; Alanine Transaminase; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Aspartate Aminotransferases; Benzoxazines; CD4-Positive T-Lymphocytes; Cyclopropanes; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Linear Models; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Factors; Stavudine; Zidovudine | 2007 |
Predictors of optimal viral suppression in patients switched to abacavir, lamivudine, and zidovudine: the Swiss HIV Cohort Study.
Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cohort Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; Genes, MDR; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Prognosis; Proportional Hazards Models; Reverse Transcriptase Inhibitors; RNA, Viral; Switzerland; Treatment Failure; Viral Load; Zidovudine | 2007 |
Evolution of bone mineral density in AIDS patients on treatment with zidovudine/lamivudine plus abacavir or lopinavir/ritonavir.
Topics: Absorptiometry, Photon; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; Case-Control Studies; Dideoxynucleosides; Femur Neck; HIV Infections; Humans; Lamivudine; Lopinavir; Lumbar Vertebrae; Male; Middle Aged; Prospective Studies; Pyrimidinones; Ritonavir; Zidovudine | 2008 |
Persistence of genotypic resistance to nelfinavir among women exposed to prophylactic antiretroviral therapy during pregnancy.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine | 2007 |
Effect of isolated V118I mutation in reverse transcriptase on response to first-line antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine | 2008 |
Maternal 12-month response to antiretroviral therapy following prevention of mother-to-child transmission of HIV type 1, Ivory Coast, 2003-2006.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cote d'Ivoire; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Microbial Sensitivity Tests; Nevirapine; Pregnancy; RNA, Viral; Treatment Outcome; Treatment Refusal; Viral Load; Zidovudine | 2008 |
18-month effectiveness of short-course antiretroviral regimens combined with alternatives to breastfeeding to prevent HIV mother-to-child transmission.
Topics: Africa; Anti-HIV Agents; Breast Feeding; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Proportional Hazards Models; Survival Rate; Treatment Outcome; Zidovudine | 2008 |
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.
Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine | 2008 |
Nucleoside reverse transcriptase inhibitors (NRTIs)-induced expression profile of mitochondria-related genes in the mouse liver.
Topics: Animals; Citric Acid Cycle; DNA, Mitochondrial; Female; Gene Expression Regulation; Lamivudine; Lipid Metabolism; Liver; Male; Mice; Microarray Analysis; Mitochondria; Oxidative Phosphorylation; Reverse Transcriptase Inhibitors; RNA; RNA, Mitochondrial; Steroids; Zidovudine | 2008 |
HIV/AIDS treatment and physicochemical quality control of medicines: evaluation of non-generic lamivudine + zidovudine tablets manufactured in Brazil.
Topics: Anti-HIV Agents; Brazil; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Industry; Lamivudine; Quality Control; Tablets; Zidovudine | 2007 |
Cost-effectiveness analysis of emtricitabine/tenofovir versus lamivudine/zidovudine, in combination with efavirenz, in antiretroviral-naive, HIV-1-infected patients.
Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cost-Benefit Analysis; Cyclopropanes; Decision Trees; Deoxycytidine; Drug Costs; Emtricitabine; Health Care Costs; Health Resources; HIV Infections; HIV-1; Humans; Lamivudine; Models, Economic; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Time Factors; Treatment Outcome; Zidovudine | 2008 |
Differential extracellular and intracellular concentrations of zidovudine and lamivudine in semen and plasma of HIV-1-infected men.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Area Under Curve; CD4 Lymphocyte Count; Extracellular Fluid; HIV-1; Humans; Intracellular Fluid; Lamivudine; Male; RNA, Viral; Semen; Zidovudine | 2008 |
Noise-induced hearing loss in mice treated with antiretroviral drugs.
Topics: Animals; Anti-Retroviral Agents; Brain Stem; Evoked Potentials, Auditory, Brain Stem; Female; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Lamivudine; Mice; Mice, Inbred CBA; Models, Statistical; Otoacoustic Emissions, Spontaneous; Time Factors; Treatment Outcome; Zidovudine | 2008 |
Prospective cohort study of HIV post-exposure prophylaxis for sexual assault survivors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Ontario; Pyrimidinones; Rape; Risk Factors; Zidovudine | 2008 |
FDA notifications. Tentative approval for generic lamivudine/zidovudine.
Topics: Drug Approval; Drug Combinations; Drugs, Generic; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 2007 |
High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers.
Topics: Anti-HIV Agents; Dideoxynucleotides; Female; Follow-Up Studies; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Leukocytes, Mononuclear; Male; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Thymine Nucleotides; Zidovudine | 2008 |
Rapid scaling-up of antiretroviral therapy in 10,000 adults in Côte d'Ivoire: 2-year outcomes and determinants.
Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cote d'Ivoire; Drug Administration Schedule; Female; Follow-Up Studies; HIV; HIV Infections; HIV-1; HIV-2; Humans; Lamivudine; Male; Nevirapine; Survival Analysis; Treatment Outcome; Zidovudine | 2008 |
New formulations approved for children.
Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Child; Child, Preschool; Dideoxynucleosides; Drug Approval; Drug Combinations; European Union; HIV Infections; Humans; Infant; Infant, Newborn; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine | 2008 |
Targeting only reverse transcriptase with zidovudine/lamivudine/abacavir plus tenofovir in HIV-1-infected patients with multidrug-resistant virus: a multicentre pilot study.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Thymidine; Viral Load; Zidovudine | 2008 |
[Evaluation of antiretroviral therapy in HIV-infected adults in the Department of Haematology, University Hospital of Brazzavllle, Congo].
Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Congo; Cyclopropanes; Didanosine; Drug Evaluation; Drug Therapy, Combination; Female; Hematology; HIV Infections; Hospital Departments; Hospitals, University; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2008 |
Cytokine and sex hormone effects on zidovudine- and lamivudine-triphosphate concentrations in vitro.
Topics: Adipocytes; Cytidine Triphosphate; Cytokines; Dideoxynucleotides; Female; Gonadal Steroid Hormones; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Zidovudine | 2008 |
The nucleoside reverse transcriptase inhibitors didanosine, lamivudine, stavudine and zidovudine show little effect on the virulence of Candida albicans in vitro.
Topics: Antifungal Agents; Biofilms; Candida albicans; Cell Adhesion; Cell Line; Didanosine; Humans; Lamivudine; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Virulence; Zidovudine | 2008 |
FDA notifications. FDA approval for generic lamivudine/zidovudine.
Topics: Drug Approval; Drugs, Generic; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 2008 |
Modelled in vivo HIV fitness under drug selective pressure and estimated genetic barrier towards resistance are predictive for virological response.
Topics: Adult; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Models, Biological; Mutation; Nelfinavir; Predictive Value of Tests; Retrospective Studies; Reverse Transcriptase Inhibitors; Time Factors; Treatment Failure; Viral Load; Zidovudine | 2008 |
[Screening of HIV-1 replication inhibitors by using pseudotyped virus system].
Topics: Anti-HIV Agents; Didanosine; DNA Replication; Drug Evaluation, Preclinical; Genes, Reporter; HIV-1; Humans; Lamivudine; Pseudocowpox Virus; Tumor Cells, Cultured; Virus Replication; Zidovudine | 2008 |
Noncirrhotic portal hypertension in patients with human immunodeficiency virus-1 infection.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; HIV-1; Humans; Hypertension, Portal; Lamivudine; Male; Middle Aged; Risk Factors; Thrombophilia; Viral Load; Zidovudine | 2008 |
Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region.
Topics: Amino Acid Sequence; Anti-HIV Agents; Codon; Crystallography, X-Ray; Deoxycytosine Nucleotides; DNA, Viral; Drug Resistance, Multiple, Viral; Foscarnet; HIV Infections; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Conformation; Reverse Transcriptase Inhibitors; Sequence Alignment; Sequence Deletion; Zidovudine | 2008 |
Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cote d'Ivoire; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Nevirapine; Perinatal Mortality; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Zidovudine | 2008 |
A case of human bite by an 11-year old HIV positive girl in a paediatrics ward.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Bites, Human; Child; Cyclopropanes; Female; HIV Infections; Humans; Inpatients; Lamivudine; Male; Zidovudine | 2008 |
Incidence of abacavir hypersensitivity reactions in euroSIDA.
Topics: Adult; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Europe; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Middle Aged; Poisson Distribution; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine | 2008 |
New depot forms of AZT and 3TC based on their phosphonate derivatives: anti-HIV activity and pharmacokinetic parameters.
Topics: Animals; Antiviral Agents; Cell Line; Dogs; Lamivudine; Mice; Organophosphonates; Zidovudine | 2008 |
Two-year outcomes of children on non-nucleoside reverse transcriptase inhibitor and protease inhibitor regimens in a South African pediatric antiretroviral program.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Lopinavir; Male; Multivariate Analysis; Pyrimidinones; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; South Africa; Stavudine; Treatment Outcome; Zidovudine | 2008 |
Interference of cell cycle progression by zidovudine and lamivudine in NIH 3T3 cells.
Topics: Animals; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Proliferation; Cell Survival; DNA; Flow Cytometry; Lamivudine; Mice; Necrosis; NIH 3T3 Cells; Zidovudine | 2009 |
HIV postexposure prophylaxis after sexual assault: why is it so hard to accomplish?
Topics: Adolescent; Animals; Anti-HIV Agents; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Macaca mulatta; Pyrimidinones; Sex Offenses; Zidovudine | 2008 |
The use of shift reagents in ion mobility-mass spectrometry: studies on the complexation of an active pharmaceutical ingredient with polyethylene glycol excipients.
Topics: Algorithms; Anti-HIV Agents; Cations; Chemistry, Pharmaceutical; Drug Combinations; Excipients; Lamivudine; Polyethylene Glycols; Protons; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Zidovudine | 2009 |
Tolerability of fosamprenavir/ritonavir associated with zidovudine-lamivudine used as postexposure prophylaxis for HIV infection.
Topics: Adult; Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Female; Furans; HIV Infections; Humans; Lamivudine; Male; Organophosphates; Prospective Studies; Ritonavir; Sulfonamides; Zidovudine | 2008 |
[A case of acquired encephalopathy in a child. A cause that we thought had disappeared].
Topics: AIDS Dementia Complex; Anti-HIV Agents; Anti-Infective Agents; Drug Therapy, Combination; Female; Fluconazole; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Polymerase Chain Reaction; Pyrimidinones; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine | 2008 |
Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1.
Topics: Base Sequence; Case-Control Studies; DNA Primers; DNA, Mitochondrial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Mutation; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; RNA, Transfer; Umbilical Cord; Zidovudine | 2009 |
Doxorubicin-induced hyperpigmentation.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Carbamates; Doxorubicin; Drug Combinations; Furans; Humans; Lamivudine; Lip Diseases; Male; Melanosis; Nails, Malformed; Organophosphates; Ritonavir; Sarcoma, Kaposi; Sulfonamides; Tongue Diseases; Zidovudine | 2008 |
Murine cardiac mtDNA: effects of transgenic manipulation of nucleoside phosphorylation.
Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiomyopathy, Dilated; Cell Line; DNA, Mitochondrial; Echocardiography; Female; Heart Ventricles; Hypertrophy, Left Ventricular; Indinavir; Lamivudine; Male; Mice; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; Phosphorylation; Reverse Transcriptase Inhibitors; Thymidine Kinase; Zidovudine | 2009 |
Development of a liquid chromatographic assay for an anti-HIV tablet containing lamivudine, zidovudine and TMC278.HCL.
Topics: Anti-HIV Agents; Biological Assay; Calibration; Chemistry, Pharmaceutical; Chromatography, Liquid; HIV; Humans; Lamivudine; Light; Molecular Structure; Nitriles; Pyrimidines; Reference Standards; Rilpivirine; Scattering, Radiation; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Tablets; Zidovudine | 2009 |
Antiretroviral concentrations in breast-feeding infants of mothers receiving highly active antiretroviral therapy.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood; Breast Feeding; Clinical Trials, Phase II as Topic; Desiccation; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lactation; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Young Adult; Zidovudine | 2009 |
A prospective study evaluating clinical outcomes and costs of three NNRTI-based HAART regimens in Kerala, India.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; India; Lamivudine; Male; Medication Adherence; Nevirapine; Prospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2009 |
Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3.
Topics: Animals; Anti-HIV Agents; Binding Sites; Biological Transport, Active; CHO Cells; Cricetinae; Cricetulus; Dideoxynucleosides; Drug Interactions; Humans; Kinetics; Lamivudine; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Reverse Transcriptase Inhibitors; Transfection; Zidovudine | 2009 |
[Analysis of pre-treatment screening on 160 HIV/AIDS patients receiving highly active antiretroviral therapy ( AZT +3TC + EFV) treatment].
Topics: Adult; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Treatment Outcome; Zidovudine | 2008 |
Switching Combivir to Truvada keeps HIV undetectable, improves blood fats, fails to improve limb fat.
Topics: Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Lamivudine; Lipids; Lipodystrophy; Organophosphorus Compounds; Viral Load; Zidovudine | 2008 |
Improvement of sensitivity and selectivity of high-performance liquid chromatography for anti-retroviral drugs (non-reverse transcriptase inhibitors) by diamond-electrode electrochemical and fluorescence detection.
Topics: Anti-Retroviral Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Electrochemical Techniques; Fluorescence; Humans; Lamivudine; Linear Models; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Water; Zidovudine | 2009 |
Prevention of vaginal simian immunodeficiency virus transmission in macaques by postexposure prophylaxis with zidovudine, lamivudine and indinavir.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Indinavir; Injections, Subcutaneous; Lamivudine; Macaca fascicularis; Sexually Transmitted Diseases, Viral; Simian Acquired Immunodeficiency Syndrome; Vagina; Viral Load; Viremia; Zidovudine | 2009 |
Emergence of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child.
Topics: Adult; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation, Missense; Nelfinavir; Phylogeny; Point Mutation; Pregnancy; Pregnancy Complications, Infectious; Selection, Genetic; Zidovudine | 2009 |
Resistance to antiretrovirals in HIV-infected pregnant women.
Topics: Adult; Anti-HIV Agents; Data Interpretation, Statistical; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Viral Load; Zidovudine | 2009 |
The obstetric face and challenge of HIV/AIDS.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Anti-Infective Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; Developing Countries; Disease Progression; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Maternal Mortality; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Trimethoprim, Sulfamethoxazole Drug Combination; World Health Organization; Zidovudine | 2009 |
Lamivudine/zidovudine: paediatric indication. For certain HIV-infected children.
Topics: Child; Drug Approval; Drug Therapy, Combination; Europe; HIV Infections; Humans; Lamivudine; Zidovudine | 2008 |
[Raised tattoos in a human-immunodeficiency-virus-infected patient].
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiprotozoal Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Hepatitis C, Chronic; Histiocytes; Humans; Lamivudine; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Lopinavir; Male; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Patient Compliance; Pentamidine; Pyrimidinones; Recurrence; Ritonavir; Tattooing; Zidovudine | 2009 |
Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; Gambia; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; Longitudinal Studies; Lopinavir; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Pyrimidinones; Ritonavir; Sequence Analysis, DNA; Treatment Outcome; Viral Load; Zidovudine | 2009 |
Quadruple nucleos(t)ide reverse transcriptase inhibitors-only regimen of tenofovir plus zidovudine/lamivudine/abacavir in heavily pre-treated HIV-1 infected patients: salvage therapy or backbone only?
Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation, Missense; Organophosphonates; Retrospective Studies; Salvage Therapy; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2009 |
Comparison of bidirectional lamivudine and zidovudine transport using MDCK, MDCK-MDR1, and Caco-2 cell monolayers.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Humans; Lamivudine; Tetrahydroisoquinolines; Zidovudine | 2009 |
Virological and immunological stability in HIV infected patients undergoing partial-treatment interruption.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Combinations; Drug Resistance, Viral; Enfuvirtide; Female; HIV Envelope Protein gp41; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Peptide Fragments; Treatment Outcome; Viral Load; Withholding Treatment; Zidovudine | 2009 |
[Tolerance study of a triple first-line antiretroviral combination zidovudine, lamivudine and efavirenz in Dakar, Senegal].
Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anemia; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Drug Tolerance; HIV-1; Humans; Lamivudine; Senegal; Zidovudine | 2009 |
Adherence to antiretroviral drug therapy in children with HIV/AIDS in Jamaica.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; Anti-Retroviral Agents; Biomarkers; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Female; HIV Infections; Humans; Infant; Jamaica; Lamivudine; Male; Medication Adherence; Nevirapine; Surveys and Questionnaires; Young Adult; Zidovudine | 2008 |
The absence of HIV mutations in cerebrospinal fluid and in peripheral blood mononuclear cells during a regimen containing Trizivir plus tenofovir.
Topics: Adenine; Anti-HIV Agents; Cohort Studies; Drug Combinations; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Mutation; Organophosphonates; Prospective Studies; Tenofovir; Viremia; Zidovudine | 2009 |
Confluent molluscum contagiosum covering the eyelids of an HIV-positive child.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child, Preschool; Drug Therapy, Combination; Eye Infections, Viral; Eyelid Diseases; HIV Seropositivity; Humans; Lamivudine; Male; Molluscum Contagiosum; Nevirapine; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Zidovudine | 2009 |
FDA notifications. Generic lamivudine/zidovudine approved.
Topics: Drug Approval; Drug Combinations; Drugs, Generic; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 2009 |
FDA notifications. Lamivudine/zidovudine tab tentatively approved.
Topics: Drug Approval; Drug Combinations; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tablets; United States; United States Food and Drug Administration; Zidovudine | 2009 |
Mother-to-child HIV and HHV-8 transmission in neonates at Saint Camille Medical Centre in Burkina Faso.
Topics: Adult; Anti-HIV Agents; Burkina Faso; CD4 Lymphocyte Count; DNA, Viral; Female; Herpesviridae Infections; Herpesvirus 8, Human; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Young Adult; Zidovudine | 2009 |
Serial knife stabbings with HIV exposure--implications for post-exposure prophylaxis.
Topics: Anti-HIV Agents; Crime Victims; Disease Transmission, Infectious; Drug Combinations; Hepatitis B; Hepatitis C; HIV Infections; Humans; Lamivudine; Lopinavir; Post-Exposure Prophylaxis; Pyrimidinones; Viral Load; Wounds, Stab; Zidovudine | 2010 |
Antiretroviral strategies to prevent mother-to-child transmission of HIV: striking a balance between efficacy, feasibility, and resistance.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 2009 |
Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine | 2010 |
FDA notifications. Tentative approval given for combination of abacavir, lamivudine & zidovudine tablets.
Topics: Dideoxynucleosides; Drug Approval; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tablets; United States; United States Food and Drug Administration; Zidovudine | 2009 |
Satisfactory cross-cultural validity of the ACTG symptom distress module in HIV-1-infected antiretroviral-naive patients.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cultural Competency; Cyclohexanes; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Language; Male; Maraviroc; Middle Aged; Multicenter Studies as Topic; Psychometrics; Randomized Controlled Trials as Topic; Reproducibility of Results; Stress, Psychological; Surveys and Questionnaires; Triazoles; Zidovudine | 2009 |
Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women.
Topics: Anti-HIV Agents; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Longitudinal Studies; Monocytes; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Reference Values; Reverse Transcriptase Inhibitors; Zidovudine | 2009 |
FDA notifications. Lamivudine/zidovudine combination approved for pediatric use.
Topics: Child; Drug Approval; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 2009 |
Development of an allele-specific PCR for detection of the K65R resistance mutation in patients infected with subtype C human immunodeficiency virus type 1.
Topics: Alkynes; Alleles; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Polymerase Chain Reaction; Zidovudine | 2010 |
Low-abundance HIV species and their impact on mutational profiles in patients with virological failure on once-daily abacavir/lamivudine/zidovudine and tenofovir.
Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Organophosphonates; RNA, Viral; Tenofovir; Treatment Failure; Viremia; Young Adult; Zidovudine | 2010 |
Specification of covariance structure in longitudinal data analysis for randomized clinical trials.
Topics: Acquired Immunodeficiency Syndrome; Bias; CD4 Lymphocyte Count; Computer Simulation; Humans; Indinavir; Lamivudine; Longitudinal Studies; Models, Statistical; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Zidovudine | 2010 |
Postmarketing in vitro/in vivo assessment of fixed dose combination products of first line antiretrovirals.
Topics: Antiviral Agents; Area Under Curve; Chromatography, High Pressure Liquid; Clinical Protocols; Confidence Intervals; Drugs, Generic; Humans; Lamivudine; Pharmaceutical Preparations; Tablets; Therapeutic Equivalency; Zidovudine | 2010 |
Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.
Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Oligopeptides; Organophosphonates; Proportional Hazards Models; Prospective Studies; Pyridines; Pyrimidinones; Risk Factors; Switzerland; Tenofovir; Zidovudine | 2010 |
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Echocardiography; Female; Fetus; Heart; Lamivudine; Male; Maternal-Fetal Exchange; Mice; Microscopy, Electron, Transmission; Mitochondria, Heart; Mutation; Myocardium; Organ Size; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Characteristics; Zidovudine | 2010 |
In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.
Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Drug Therapy, Combination; Echocardiography; Electron Transport Chain Complex Proteins; Electrophoresis, Polyacrylamide Gel; Female; Heart; Lamivudine; Luminescent Measurements; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardium; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine | 2010 |
Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase.
Topics: Cell Line; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Ribonuclease H, Human Immunodeficiency Virus; Selection, Genetic; Statistics, Nonparametric; Zidovudine | 2010 |
Analysis of RT sequences of subtype C HIV-type 1 isolates from indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; India; Lamivudine; Molecular Sequence Data; Nevirapine; Polymorphism, Single Nucleotide; Stavudine; Treatment Failure; Zidovudine | 2010 |
Resistance pathways of human immunodeficiency virus type 1 against the combination of zidovudine and lamivudine.
Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Evolution, Molecular; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation, Missense; Point Mutation; RNA, Viral; Selection, Genetic; Zidovudine | 2010 |
[Durability and tolerability of long-term nevirapine-based HAART].
Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Comorbidity; Dideoxynucleosides; Female; Hepatitis, Viral, Human; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lipids; Liver Function Tests; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Viral Load; Young Adult; Zidovudine | 2010 |
Identification, isolation, and characterization of potential degradation products in a triple combination lamivudine, zidovudine, and nevirapine tablet for oral suspension.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Contamination; Indicators and Reagents; Lamivudine; Magnetic Resonance Spectroscopy; Nevirapine; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Suspensions; Tablets; Zidovudine | 2010 |
Simultaneous determination of stavudine and lamivudine in human plasma by high performance liquid chromatography and its application to a bioavailability study.
Topics: Anti-HIV Agents; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Humans; Lamivudine; Reference Standards; Stavudine; Zidovudine | 2010 |
Addition of 7 days of zidovudine plus lamivudine to peripartum single-dose nevirapine effectively reduces nevirapine resistance postpartum in HIV-infected mothers in Malawi.
Topics: Adolescent; Adult; Anti-HIV Agents; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Malawi; Nevirapine; Plasma; Polymerase Chain Reaction; Postpartum Period; Pregnancy; RNA, Viral; Sequence Analysis, DNA; Young Adult; Zidovudine | 2010 |
Immunological response to highly active antiretroviral therapy following treatment for prevention of mother to child transmission of HIV-1: a study in Côte d'Ivoire.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cote d'Ivoire; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Treatment Outcome; Zidovudine | 2010 |
Evolution of drug resistance during 48 weeks of zidovudine/lamivudine/tenofovir in the absence of real-time viral load monitoring.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Genotype; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Tenofovir; Time Factors; Viral Load; Zidovudine | 2010 |
Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs).
Topics: Animals; Animals, Newborn; Cerebral Cortex; Didanosine; Disease Models, Animal; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Lamivudine; Maternal Exposure; Mitochondria, Liver; Oxidative Phosphorylation; Pregnancy; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2010 |
Recent FDA approvals and changes.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Approval; Drug Combinations; Drugs, Generic; HIV Antibodies; HIV Core Protein p24; HIV Infections; HIV-1; HIV-2; Humans; Lamivudine; Nevirapine; Reagent Kits, Diagnostic; Reverse Transcriptase Inhibitors; Tablets; United States; United States Food and Drug Administration; Zidovudine | 2010 |
Genotypic and phenotypic cross-drug resistance of harboring drug-resistant HIV type 1 subtype B' strains from former blood donors in central Chinese provinces.
Topics: Adult; Anti-HIV Agents; Blood Donors; China; Didanosine; Drug Resistance, Multiple, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Phenotype; pol Gene Products, Human Immunodeficiency Virus; RNA, Viral; Sequence Analysis, RNA; Stavudine; Zidovudine | 2010 |
Stavudine toxicity in women is the main reason for treatment change in a 3-year prospective cohort of adult patients started on first-line antiretroviral treatment in Uganda.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Multivariate Analysis; Nevirapine; Prospective Studies; Risk Factors; Sex Factors; Stavudine; Uganda; Zidovudine | 2011 |
Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiretroviral Therapy, Highly Active; Drug Administration Schedule; HIV Protease Inhibitors; Indinavir; Lamivudine; Macaca fascicularis; Male; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Time Factors; Tissue Distribution; Viremia; Zidovudine | 2010 |
Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine | 2010 |
[Human immunodeficiency virus and Chagas disease coinfection treated successfully with benznidazole and a raltegravir-based antiretroviral regimen: a case report].
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Chagas Disease; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Nitroimidazoles; Oligopeptides; Organophosphonates; Paraguay; Pyridines; Pyrrolidinones; Raltegravir Potassium; Ritonavir; Spain; Tenofovir; Trypanocidal Agents; Zidovudine | 2011 |
Reduced dose of stavudine and lipoatrophy in HIV-infected patients in Cameroon.
Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Male; Middle Aged; Nevirapine; Stavudine; Zidovudine | 2010 |
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases.
Topics: Adenine; Anti-HIV Agents; DNA-Directed DNA Polymerase; Humans; Lamivudine; Molecular Structure; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tenofovir; Zidovudine | 2011 |
Determinants of individual variation in intracellular accumulation of anti-HIV nucleoside analog metabolites.
Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cross-Sectional Studies; Deoxycytidine Kinase; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Nucleosides; Polyphosphates; Sex Factors; Stavudine; Thymidine Kinase; Treatment Outcome; Zidovudine | 2011 |
Aminotransferase serum levels decrease after initiating antiretroviral treatment in HIV infected patients.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Lopinavir; Male; Pyrimidinones; Ritonavir; Serum; Transaminases; Zidovudine | 2011 |
[Morphological and physiological analysis of livers and kidneys of pregnant rats and their fetuses treated by the association of zidovudine, lamivudine and ritonavir for the whole period of pregnancy].
Topics: Animals; Anti-HIV Agents; Female; Fetus; Kidney; Lamivudine; Liver; Pregnancy; Rats; Rats, Wistar; Ritonavir; Zidovudine | 2010 |
FDA notifications. FDA tentatively approves fixed-dose lamivudine/zidovudine.
Topics: Drug Approval; Drug Combinations; Drugs, Generic; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 2010 |
Validation of a sensitive LC/MS/MS method for the determination of zidovudine and lamivudine in human plasma.
Topics: Chromatography, Liquid; Drug Stability; Humans; Lamivudine; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Zidovudine | 2012 |
Chronic action of association of zidovudine, lamivudine and ritonavir on pregnant rats. A biologic assay.
Topics: Animals; Animals, Newborn; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Weight; Female; Lamivudine; Litter Size; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar; Ritonavir; Statistics, Nonparametric; Zidovudine | 2011 |
FDA notifications. Fixed dose ART approved by FDA.
Topics: Dose-Response Relationship, Drug; Drug Approval; Drug Combinations; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine | 2011 |
Improving retention in the early infant diagnosis of HIV program in rural Mozambique by better service integration.
Topics: Adult; Anti-HIV Agents; Delivery of Health Care; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mozambique; Nevirapine; Pregnancy; Retrospective Studies; Rural Population; Young Adult; Zidovudine | 2011 |
Joint population pharmacokinetic analysis of zidovudine, lamivudine, and their active intracellular metabolites in HIV patients.
Topics: Adult; Anti-HIV Agents; Chromatography, Liquid; Cytidine Triphosphate; Dideoxynucleotides; Female; Humans; Lamivudine; Male; Middle Aged; Models, Theoretical; Sex Factors; Tandem Mass Spectrometry; Young Adult; Zidovudine | 2011 |
Combination antiretroviral therapy as treatment for human immunodeficiency virus-associated mucosa-associated lymphoid tissue type lymphoma of the nasopharynx.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Humans; Lamivudine; Lopinavir; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Male; Middle Aged; Nasopharyngeal Neoplasms; Pyrimidinones; Radiotherapy, Adjuvant; Remission Induction; Ritonavir; Viral Load; Zidovudine | 2011 |
Evaluation of saliva as an alternative matrix for monitoring plasma Zidovudine, Lamivudine and nevirapine concentrations in Rwanda.
Topics: Adult; Anti-HIV Agents; Cross-Sectional Studies; Drug Monitoring; Feasibility Studies; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Nevirapine; Rwanda; Saliva; Zidovudine | 2011 |
[Comparative study of two anti-antiretroviral protocols used for treatment of a cohort of HIV 1-positive patients followed at the Institute of Public Health and Hygiene in Dakar, Senegal].
Topics: Academies and Institutes; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Seropositivity; HIV-1; Humans; Hygiene; Lamivudine; Nevirapine; Public Health; Quality of Life; Retrospective Studies; Senegal; Survival Analysis; Treatment Outcome; Zidovudine | 2011 |
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine; Diphosphates; Emtricitabine; Humans; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Organophosphonates; Phosphates; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Tenofovir; Zidovudine | 2011 |
Prevention of mother-to-child transmission of HIV and the health-related Millennium Development Goals: time for a public health approach.
Topics: Adult; Anti-HIV Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; Female; Goals; Healthy People Programs; HIV Infections; HIV Seropositivity; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Malawi; Male; Nevirapine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Public Health; United Nations; Zidovudine | 2011 |
[Coinfection with HIV and HCV: abacavir and ribavirine, why not?].
Topics: Anti-HIV Agents; Antiviral Agents; Coinfection; Dideoxynucleosides; Drug Combinations; Drug Interactions; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Ribavirin; Zidovudine | 2012 |
The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC.
Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Resistance, Viral; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Inhibitory Concentration 50; Lamivudine; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Ribonuclease H; Ribonuclease H, Human Immunodeficiency Virus; Zidovudine | 2011 |
Characterization of thermal and rheological properties of zidovudine, lamivudine and plasticizer blends with ethyl cellulose to assess their suitability for hot melt extrusion.
Topics: Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Citrates; Delayed-Action Preparations; Lamivudine; Microscopy, Polarization; Phase Transition; Plasticizers; Polyethylene Glycols; Rheology; Solubility; Thermogravimetry; Transition Temperature; Viscosity; Zidovudine | 2011 |
Management of needlestick injuries: a house officer who has a needlestick.
Topics: Anti-HIV Agents; Blood-Borne Pathogens; Drug Combinations; Emergency Service, Hospital; Health Personnel; HIV Infections; HIV Seropositivity; Humans; Internship and Residency; Lamivudine; Male; Needlestick Injuries; Occupational Exposure; Physicians; Post-Exposure Prophylaxis; Risk; United States; Zidovudine | 2012 |
Successful treatment of aciclovir and foscarnet resistant Herpes simplex virus lesions with topical imiquimod in patients infected with human immunodeficiency virus type 1.
Topics: Acyclovir; Administration, Topical; Adult; Aminoquinolines; Antiviral Agents; Drug Resistance, Viral; Foscarnet; Herpes Simplex; HIV Infections; HIV-1; Humans; Imiquimod; Lamivudine; Male; Middle Aged; Nelfinavir; Simplexvirus; Zidovudine | 2012 |
Pharmacokinetics of antiretroviral drug varies with formulation in the target population of children with HIV-1.
Topics: Administration, Oral; Antirheumatic Agents; Chemistry, Pharmaceutical; Child, Preschool; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Solutions; Tablets; Therapeutic Equivalency; Zidovudine | 2012 |
Costs and benefits of multidrug, multidose antiretroviral therapy for prevention of mother-to-child transmission of HIV in the Dominican Republic.
Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cost-Benefit Analysis; Cyclopropanes; Dominican Republic; Drug Administration Schedule; Drug Costs; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Zidovudine | 2012 |
Lopinavir/ritonavir trough concentrations with the tablet formulation in HIV-1-infected women during the third trimester of pregnancy.
Topics: Adult; Anti-HIV Agents; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Reverse Transcriptase Inhibitors; Ritonavir; Tablets; Treatment Outcome; Young Adult; Zidovudine | 2012 |
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin.
Topics: Acyclovir; Anti-HIV Agents; Cell Line; Drug Resistance, Viral; Drug Synergism; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Nevirapine; Palatine Tonsil; Protease Inhibitors; Ribavirin; T-Lymphocytes; Tissue Culture Techniques; Zidovudine | 2012 |
Recombination between variants from genital tract and plasma: evolution of multidrug-resistant HIV type 1.
Topics: Adult; Anti-HIV Agents; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Nevirapine; Plasma; Recombination, Genetic; RNA, Viral; Sequence Analysis, DNA; Zidovudine | 2012 |
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine | 2012 |
Development and validation of an HPLC-UV method for simultaneous determination of zidovudine, lamivudine, and nevirapine in human plasma and its application to pharmacokinetic study in human volunteers.
Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Humans; Lamivudine; Limit of Detection; Liquid-Liquid Extraction; Nevirapine; Zidovudine | 2013 |
Emergence of minor drug-resistant HIV-1 variants after triple antiretroviral prophylaxis for prevention of vertical HIV-1 transmission.
Topics: Adult; Alleles; Anti-Retroviral Agents; Drug Resistance, Viral; Female; Genetic Variation; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nevirapine; Oligonucleotides; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Tanzania; Zidovudine | 2012 |
Effect of HIV-1 infection and sex on the cellular pharmacology of the antiretroviral drugs zidovudine and lamivudine.
Topics: Adult; Anti-HIV Agents; Black or African American; Cytidine Triphosphate; Dideoxynucleotides; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Prospective Studies; Sex Factors; Thymine Nucleotides; Zidovudine | 2012 |
Comparative studies of lamivudine-zidovudine nanoparticles for the selective uptake by macrophages.
Topics: Animals; Anti-HIV Agents; Drug Carriers; Drug Combinations; Lactic Acid; Lamivudine; Lipids; Macrophages; Male; Mice; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polysorbates; Reverse Transcriptase Inhibitors; Surface-Active Agents; Tissue Distribution; Zidovudine | 2012 |
Simultaneous determination of lamivudine, lopinavir, ritonavir, and zidovudine concentration in plasma of HIV-infected patients by HPLC-MS/MS.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; HIV Infections; Humans; Lamivudine; Limit of Detection; Lopinavir; Reference Standards; Reproducibility of Results; Ritonavir; Tandem Mass Spectrometry; Zidovudine | 2012 |
Impact of short-term HAART initiated during the chronic stage or shortly post-exposure on SIV infection of male genital organs.
Topics: Animals; Antiretroviral Therapy, Highly Active; Genitalia, Male; Indinavir; Lamivudine; Macaca fascicularis; Male; RNA, Viral; Semen; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Viral Load; Zidovudine | 2012 |
Response to valacyclovir in an HIV-infected girl with Epstein Barr infection.
Topics: Acyclovir; Alkynes; Antiretroviral Therapy, Highly Active; Antiviral Agents; Benzoxazines; Child; Cyclopropanes; Epstein-Barr Virus Infections; Female; HIV Infections; Humans; Lamivudine; Valacyclovir; Valine; Zidovudine | 2012 |
Evaluation of different antiretroviral drug protocols on naturally infected feline immunodeficiency virus (FIV) cats in the late phase of the asymptomatic stage of infection.
Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cat Diseases; Cats; CD4-CD8 Ratio; Evoked Potentials, Auditory; Evoked Potentials, Visual; Feline Acquired Immunodeficiency Syndrome; Female; Interferon-alpha; Lamivudine; Male; Treatment Outcome; Viral Load; Zidovudine | 2012 |
Trends in HIV-1 reverse transcriptase resistance-associated mutations and antiretroviral prescription data from 2003-2010.
Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Prescriptions; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Prevalence; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Zidovudine | 2012 |
Monitoring of HAART regime antiretrovirals in serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chromatography, Liquid; Cyclopropanes; Drug Monitoring; Humans; Lamivudine; Organophosphonates; Stavudine; Tenofovir; Zidovudine | 2012 |
Evaluating the cost-effectiveness of combination antiretroviral therapy for the prevention of mother-to-child transmission of HIV in Uganda.
Topics: Anti-HIV Agents; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Uganda; Zidovudine | 2012 |
Differential in vitro kinetics of drug resistance mutation acquisition in HIV-1 RT of subtypes B and C.
Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Zidovudine | 2012 |
Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes.
Topics: Adipocytes; Adipogenesis; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 5; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Chromones; Flow Cytometry; Humans; Lamivudine; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Mitochondria; Morpholines; Nocodazole; Phagosomes; Reverse Transcriptase Inhibitors; RNA, Small Interfering; Stavudine; Wortmannin; Zidovudine | 2013 |
Synergistic antivirus effect of combined administration of Combivir with Angelica polysaccharide sulfate.
Topics: Animals; Anti-HIV Agents; Bone Marrow Cells; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Humans; Lamivudine; Lethal Dose 50; Leukemia Virus, Murine; Mice; Mice, Inbred BALB C; Organ Size; Polysaccharides; Thymus Gland; Viral Load; Virus Replication; Zidovudine | 2013 |
[Acute hemolytic anemia in an HIV patient after inhalation of amyl nitrite].
Topics: Administration, Inhalation; Adult; Amyl Nitrite; Anemia, Hemolytic; Anti-HIV Agents; Diagnosis, Differential; Dideoxynucleosides; HIV Infections; Humans; Illicit Drugs; Inhalant Abuse; Iraq; Lamivudine; Male; Travel; Zidovudine | 2012 |
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria.
Topics: Adult; Alanine Transaminase; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Coinfection; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Nevirapine; Nigeria; Organophosphorus Compounds; RNA, Viral; Stavudine; Zidovudine | 2013 |
[A case of vitiligo occurring after initiation of antiretroviral treatment and disappearing during this treatment: autoimmune IRIS syndrome?].
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Follow-Up Studies; HIV Seropositivity; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Male; Viral Load; Vitiligo; Zidovudine | 2012 |
Comparative analysis of genetic toxicity of antiretroviral combinations in somatic cells of Drosophila melanogaster.
Topics: Animals; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA Damage; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Combinations; Female; Lamivudine; Male; Mitosis; Mutation; Recombinant Proteins; Wings, Animal; Zidovudine | 2013 |
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cells, Cultured; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Enzyme Activation; Female; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Regression Analysis; Reverse Transcriptase Inhibitors; Risk Factors; Telomerase; Telomere; Telomere Shortening; Tenofovir; Time Factors; Young Adult; Zidovudine | 2013 |
Risk adapted transmission prophylaxis to prevent vertical HIV-1 transmission: effectiveness and safety of an abbreviated regimen of postnatal oral zidovudine.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Risk Factors; Treatment Outcome; Zidovudine | 2013 |
Toxicology and carcinogenesis studies of mixtures of 3'-azido-3'-deoxythymidine (AZT), lamivudine (3TC), nevirapine (NVP), and nelfinavir mesylate (NFV) (Cas Nos. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice (transplacental exposure s
Topics: Administration, Oral; Animals; Anti-Retroviral Agents; DNA; Drug Therapy, Combination; Escherichia coli; Female; Lamivudine; Longevity; Male; Maternal Exposure; Mice; Mice, Inbred Strains; Nelfinavir; Nevirapine; Pregnancy; Prenatal Exposure Delayed Effects; Salmonella typhimurium; Skin Neoplasms; Zidovudine | 2013 |
High throughput LC-MS/MS method for simultaneous determination of zidovudine, lamivudine and nevirapine in human plasma.
Topics: Anti-HIV Agents; Chromatography, Liquid; Humans; Lamivudine; Male; Nevirapine; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Zidovudine | 2013 |
Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion.
Topics: Anti-HIV Agents; Calcitriol; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Reverse Transcriptase; Humans; Infant; Lamivudine; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Vitamins; Zidovudine | 2013 |
Tropical spastic paraparesis treated with Combivir (lamivudine-zidovudine).
Topics: Aged; Drug Combinations; Female; Human T-lymphotropic virus 1; Humans; Lamivudine; Paraparesis, Tropical Spastic; Severity of Illness Index; Treatment Outcome; Zidovudine | 2013 |
The stress response resolution assay. II. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.
Topics: Amphotericin B; Animals; Cell Cycle Checkpoints; Cell Death; Cell Line; Cell Proliferation; Cell Shape; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Ethylnitrosourea; Guanine Nucleotides; Humans; Hypoxanthine Phosphoribosyltransferase; Lamivudine; Mice; Mutagens; Mutation; Phenotype; Stress, Physiological; Thionucleotides; Toxicity Tests; Zidovudine | 2013 |
The stress response resolution assay. I. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.
Topics: Amphotericin B; Animals; Calibration; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Pollutants; Epithelial Cells; Epithelium; Ethylnitrosourea; Guanine Nucleotides; Humans; Lamivudine; Mice; Mutagens; Stress, Physiological; Thionucleotides; Toxicity Tests; Zidovudine | 2013 |
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine | 2013 |
Talk of HIV cure goes viral.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Child, Preschool; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Male; Nevirapine; Primary Prevention; Ritonavir; Secondary Prevention; Time Factors; Zidovudine | 2013 |
Left ventricular hypertrophy detected by echocardiography in HIV-infected patients.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Carbamates; Comorbidity; Cross-Sectional Studies; Cyclopropanes; Diabetes Mellitus; Drug Combinations; Dyslipidemias; Echocardiography; Female; Furans; HIV Infections; Humans; Hypertension; Hypertrophy, Left Ventricular; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Ritonavir; Smoking; Spain; Sulfonamides; Tenofovir; Zidovudine | 2013 |
Antiretroviral drugs in Africa: a public health versus a market approach.
Topics: Africa; Anti-HIV Agents; Drug Packaging; Health Resources; Health Services Accessibility; HIV Infections; Humans; Lamivudine; Nevirapine; Public Health; Zidovudine | 2013 |
Drug-resistance development differs between HIV-1-infected patients failing first-line antiretroviral therapy containing nonnucleoside reverse transcriptase inhibitors with and without thymidine analogues.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Tenofovir; Thymidine; Treatment Failure; Viral Load; Zidovudine | 2013 |
Characterization of antiviral activity of benzamide derivative AH0109 against HIV-1 infection.
Topics: Active Transport, Cell Nucleus; CD4-Positive T-Lymphocytes; DNA, Viral; Drug Evaluation, Preclinical; HEK293 Cells; HIV Integrase Inhibitors; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Morphinans; Nevirapine; Reverse Transcriptase Inhibitors; Reverse Transcription; Virus Replication; Zidovudine | 2013 |
Baseline CD4 cell counts and outcomes among adult treatment naive HIV patients after taking fixed dose combination GPO-VIR-S and GPO-VIR-Z in Thailand.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Female; Hematologic Tests; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Kaplan-Meier Estimate; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Thailand; Treatment Outcome; Viral Load; Zidovudine | 2013 |
Economic evaluation of 3-drug antiretroviral regimens for the prevention of mother-to-child HIV transmission in Thailand.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cost-Benefit Analysis; Cyclopropanes; Drug Therapy, Combination; Female; Health Services; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Models, Econometric; Mothers; Nevirapine; Pregnancy; Thailand; Zidovudine | 2015 |
Adherence to antiretroviral therapy among HIV infected children measured by caretaker report, medication return, and drug level in Dar Es Salaam, Tanzania.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Caregivers; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Drug Administration Schedule; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Medication Adherence; Middle Aged; Nevirapine; Odds Ratio; Stavudine; Surveys and Questionnaires; Tanzania; Young Adult; Zidovudine | 2013 |
Clinical experience of raltegravir with abacavir/lamivudine or zidovudine/lamivudine in HIV-infected Korean adults.
Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lipids; Male; Middle Aged; Prospective Studies; Pyrrolidinones; Raltegravir Potassium; Republic of Korea; Retrospective Studies; Treatment Outcome; Viral Load; Young Adult; Zidovudine | 2013 |
HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Resistance, Viral; Epidemiological Monitoring; Female; Ghana; HIV Infections; HIV Protease; HIV-1; Humans; Infant; Lamivudine; Male; Middle Aged; Molecular Epidemiology; Molecular Typing; Mutation, Missense; Nevirapine; Prevalence; Sequence Analysis, DNA; Stavudine; Zidovudine | 2013 |
Anemia and risk factors in HAART naïve and HAART experienced HIV positive persons in south west Ethiopia: a comparative study.
Topics: Adolescent; Adult; Anemia; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nevirapine; Risk Factors; Social Class; Surveys and Questionnaires; Zidovudine | 2013 |
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa.
Topics: Adolescent; Adult; Alkynes; Analysis of Variance; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Outcome Assessment, Health Care; Prevalence; South Africa; Stavudine; Young Adult; Zidovudine | 2013 |
Child cured of HIV: can this be repeated?
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine | 2013 |
[Evaluation of tolerance of zidovudine-lamivudine-nevirapine combination in HIV 1 patients in Fann Teaching Hospital in Dakar].
Topics: Adult; Anti-HIV Agents; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Senegal; Zidovudine | 2013 |
Continuous wavelet transforms for the simultaneous quantitative analysis and dissolution testing of lamivudine-zidovudine tablets.
Topics: Anti-HIV Agents; Drug Combinations; Lamivudine; Solubility; Tablets; Wavelet Analysis; Zidovudine | 2013 |
Trends in clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Shanghai from 2006 to 2011.
Topics: Adolescent; Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; China; Cross-Sectional Studies; Female; HIV Infections; Humans; Immune Tolerance; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Viral Load; Zidovudine | 2014 |
Preliminary study of quinine pharmacokinetics in pregnant women with malaria-HIV co-infection.
Topics: Adult; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Coinfection; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria, Falciparum; Nevirapine; Parasite Load; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Quinidine; Quinine; Stavudine; Treatment Outcome; Young Adult; Zidovudine | 2014 |
Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy.
Topics: Adolescent; Adult; Amodiaquine; Anti-Retroviral Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria; Male; Middle Aged; Nevirapine; Nigeria; Plasma; Young Adult; Zidovudine | 2014 |
Long-term exposure of mice to nucleoside analogues disrupts mitochondrial DNA maintenance in cortical neurons.
Topics: Animals; Antimetabolites; Cells, Cultured; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Liver; Mice; Mitochondria; Muscle, Skeletal; Neurons; Stavudine; Zidovudine | 2014 |
Clinical profile and response to first-line ARV in HIV patients from Eastern UP and Bihar: a retrospective study.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Young Adult; Zidovudine | 2013 |
Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes.
Topics: Adult; Alkynes; Area Under Curve; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genotype; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Mutation; Pharmacogenetics; Reverse Transcriptase Inhibitors; Treatment Outcome; Uganda; Zidovudine | 2014 |
Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2) in Genetically Modified C3B6.129F1-Trp53(tm1Brd) N12 Haploinsufficient Mice (in u
Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Anti-HIV Agents; Body Weight; Chemistry, Pharmaceutical; Drug Combinations; Female; Haploinsufficiency; Intubation, Gastrointestinal; Lamivudine; Litter Size; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Nevirapine; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Reverse Transcriptase Inhibitors; Survival; Zidovudine | 2013 |
Hepatitis B and C co-infection among HIV-infected adults while on antiretroviral treatment: long-term survival, CD4 cell count recovery and antiretroviral toxicity in Cambodia.
Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cambodia; CD4 Lymphocyte Count; Coinfection; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Liver; Logistic Models; Male; Middle Aged; Nevirapine; Proportional Hazards Models; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2014 |
Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Case-Control Studies; Drug Combinations; Drug Therapy, Combination; Genome-Wide Association Study; Genotype; Humans; Lamivudine; Multicenter Studies as Topic; Peripheral Nervous System Diseases; Polymorphism, Genetic; Principal Component Analysis; Randomized Controlled Trials as Topic; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine | 2014 |
Challenges of antiretroviral treatment monitoring in rural and remote-access regions in Africa.
Topics: Acquired Immunodeficiency Syndrome; Adult; Africa; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Monitoring; Drug Resistance, Viral; Female; HIV-1; Hospitals, Rural; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Rural Health Services; Rural Population; Stavudine; Treatment Outcome; Zidovudine | 2014 |
New dinucleoside phosphonate derivatives as prodrugs of 3'-azido-3'-deoxythymidine and β-L-2',3'-dideoxy-3'-thiacytidine: synthesis and anti-HIV properties.
Topics: Anti-HIV Agents; Cell Line; Drug Stability; HIV-1; Humans; Hydrolysis; Lamivudine; Microbial Sensitivity Tests; Nuclear Magnetic Resonance, Biomolecular; Prodrugs; Zidovudine | 2014 |
The financial and service implications of splitting fixed-dose antiretroviral drugs - a case study.
Topics: Adult; Aged; Anti-HIV Agents; Cost-Benefit Analysis; Costs and Cost Analysis; Drug Combinations; Drug Substitution; Female; Health Care Costs; HIV Infections; Humans; Lamivudine; Male; Treatment Outcome; Viral Load; Zidovudine | 2015 |
Spectra resolution for simultaneous spectrophotometric determination of lamivudine and zidovudine components in pharmaceutical formulation of human immunodeficiency virus drug based on using continuous wavelet transform and derivative transform techniques
Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Combinations; Lamivudine; Spectrophotometry, Ultraviolet; Wavelet Analysis; Zidovudine | 2014 |
Presence of HIV drug resistance in antiretroviral therapy-naive and -experienced patients from Papua New Guinea.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dried Blood Spot Testing; Drug Resistance, Viral; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Papua New Guinea; Reverse Transcriptase Inhibitors; Stavudine; Treatment Failure; Viral Load; Young Adult; Zidovudine | 2014 |
Clinical manifestations and treatment outcomes in HIV-1-infected children receiving antiretroviral therapy in Karachi, Pakistan.
Topics: Anti-HIV Agents; Body Height; Body Weight; CD4 Lymphocyte Count; Child, Preschool; Drug Resistance, Viral; Female; Genotype; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Pakistan; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine | 2014 |
Sustained increase of serum creatine phosphokinase levels and progressive muscle abnormalities associated with raltegravir use during 32-week follow-up in an HIV-1 experienced patient on simplified HAART regimen, intolerant to protease inhibitors and abac
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Creatine Kinase; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Muscle Weakness; Myalgia; Pyrrolidinones; Raltegravir Potassium; Zidovudine | 2013 |
Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).
Topics: Alkynes; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Benzoxazines; Cell Line; Cognition Disorders; Cyclopropanes; Female; HIV Infections; Humans; Lamivudine; Mice; Oxidative Stress; Phagocytosis; Reverse Transcriptase Inhibitors; Zidovudine | 2014 |
Extensive pulmonary involvement with raltegravir-induced DRESS syndrome in a postpartum woman with HIV.
Topics: Adolescent; Anti-HIV Agents; Drug Combinations; Drug Hypersensitivity Syndrome; Female; HIV Infections; HIV Integrase Inhibitors; Humans; Lamivudine; Lopinavir; Pleural Effusion; Postpartum Period; Pyrrolidinones; Radiography; Raltegravir Potassium; Respiratory Distress Syndrome; Ritonavir; Zidovudine | 2014 |
MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Drug Resistance, Viral; Female; Gene Expression Regulation; HIV; Humans; Lamivudine; Leukocytes, Mononuclear; Male; MicroRNAs; Nevirapine; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 2014 |
SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Cell Line; Dideoxynucleotides; Gene Expression; Genes, Reporter; HIV Reverse Transcriptase; HIV-1; Host-Pathogen Interactions; Humans; Lamivudine; Luciferases; Monocytes; Monomeric GTP-Binding Proteins; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; SAM Domain and HD Domain-Containing Protein 1; Stavudine; Tenofovir; Virus Replication; Zidovudine | 2014 |
Impact of Y181C and/or H221Y mutation patterns of HIV-1 reverse transcriptase on phenotypic resistance to available non-nucleoside and nucleoside inhibitors in China.
Topics: Alkynes; Benzoxazines; China; Cyclopropanes; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2014 |
A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.
Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Humans; In Vitro Techniques; Lamivudine; Palatine Tonsil; Thymine Nucleotides; Virus Replication; Zidovudine | 2014 |
Side effects and tolerability of post-exposure prophylaxis with zidovudine, lamivudine, and lopinavir/ritonavir: a comparative study with HIV/AIDS patients.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Post-Exposure Prophylaxis; Retrospective Studies; Ritonavir; Zidovudine | 2014 |
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine | 2014 |
Pure red cell aplasia induced by lamivudine without the influence of zidovudine in a patient infected with human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Biopsy, Needle; Bone Marrow; Diagnosis, Differential; HIV Infections; Humans; Lamivudine; Male; Platelet Count; Red-Cell Aplasia, Pure; Young Adult; Zidovudine | 2014 |
Overexpression of mitochondrial antioxidant manganese superoxide dismutase (MnSOD) provides protection against AZT- or 3TC-induced endothelial dysfunction.
Topics: Animals; Anti-HIV Agents; Antioxidants; Aorta, Thoracic; Female; HIV Infections; Humans; Lamivudine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Superoxide Dismutase; Zidovudine | 2014 |
Lopinavir/ritonavir plus lamivudine and abacavir or zidovudine dose ratios for paediatric fixed-dose combinations.
Topics: Administration, Oral; Adolescent; Age Factors; Antiretroviral Therapy, Highly Active; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic; Computer Simulation; Dideoxynucleosides; Drug Combinations; Drug Dosage Calculations; Drug Monitoring; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Male; Models, Statistical; Ritonavir; Silybin; Silymarin; Viral Load; Zidovudine | 2015 |
Impact of combination antiretroviral therapy in the NOD.c3c4 mouse model of autoimmune biliary disease.
Topics: Amino Acid Sequence; Animals; Anti-Retroviral Agents; Biomarkers; Cholangitis; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Lamivudine; Liver Cirrhosis, Biliary; Lopinavir; Mammary Tumor Virus, Mouse; Mice, Inbred NOD; Molecular Sequence Data; Protease Inhibitors; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Time Factors; Tumor Virus Infections; Viral Load; Zidovudine | 2015 |
Persistent production of an integrase-deleted HIV-1 variant with no resistance mutation and wild-type proviral DNA in a treated patient.
Topics: Anti-HIV Agents; Base Sequence; Defective Viruses; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Immune Evasion; Integrases; Lamivudine; Leukocytes, Mononuclear; Lopinavir; Molecular Sequence Data; Proviruses; Sequence Analysis, DNA; Sequence Deletion; Viral Load; Zidovudine | 2015 |
Human immunodeficiency virus post-exposure prophylaxis: primum non nocere.
Topics: Adult; Antiviral Agents; Bipolar Disorder; Cytochrome P-450 CYP3A Inhibitors; Dihydroergotamine; Drug Synergism; Drug Therapy, Combination; Ergotism; Female; HIV Infections; Humans; Hypotension, Orthostatic; Lamivudine; Lopinavir; Post-Exposure Prophylaxis; Ritonavir; Vasoconstrictor Agents; Zidovudine | 2015 |
Is zidovudine first-line therapy virologically comparable to tenofovir in resource-limited settings?
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; Health Resources; HIV; HIV Infections; Humans; Lamivudine; Lesotho; Logistic Models; Male; Middle Aged; Organophosphonates; Tenofovir; Viral Load; Zidovudine | 2015 |
Follow-up on long-term antiretroviral therapy for cats infected with feline immunodeficiency virus.
Topics: Animals; Cat Diseases; Cats; CD8-Positive T-Lymphocytes; Feline Acquired Immunodeficiency Syndrome; Follow-Up Studies; Immunodeficiency Virus, Feline; Lamivudine; Molecular Sequence Data; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2016 |
[Analysis on HIV suppression effect after initiating antiretroviral treatment and related factors among AIDS patients in Henan province during 2008 and 2013].
Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; Health Facilities; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Stavudine; Time-to-Treatment; Treatment Outcome; Zidovudine | 2015 |
Time trends of baseline demographics and clinical characteristics of HIV infected children enrolled in care and treatment service in Dar es Salaam, Tanzania.
Topics: Adolescent; Age Distribution; Alkynes; Ambulatory Care Facilities; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Comorbidity; Cyclopropanes; Female; HIV Infections; Humans; Infant; Lamivudine; Linear Models; Male; Nevirapine; Severity of Illness Index; Tanzania; Tuberculosis; Zidovudine | 2015 |
Progress Toward Eliminating Mother to Child Transmission of HIV in Kenya: Review of Treatment Guideline Uptake and Pediatric Transmission at Four Government Hospitals Between 2010 and 2012.
Topics: Adult; Anti-HIV Agents; Child; Cohort Studies; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Early Diagnosis; Female; Gestational Age; Government; Guideline Adherence; HIV Infections; Hospitals, Public; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Kenya; Lamivudine; Medication Adherence; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Zidovudine | 2016 |
[Comparative and evolutionary profile of people infected with HIV on antiretroviral therapy in Kinshasa, Democratic Republic of Congo].
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Democratic Republic of the Congo; Disease Progression; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Ritonavir; Zidovudine | 2014 |
Serious adverse events are uncommon with combination neonatal antiretroviral prophylaxis: a retrospective case review.
Topics: Anemia; Anti-HIV Agents; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Neutropenia; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Thrombocytopenia; Zidovudine | 2015 |
Mitochondrial DNA D-loop AG/TC transition mutation in cortical neurons of mice after long-term exposure to nucleoside analogues.
Topics: Animals; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Laser Capture Microdissection; Mice; Mice, Inbred BALB C; Mutation; Neurons; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2015 |
Comparative Application of PLS and PCR Methods to Simultaneous Quantitative Estimation and Simultaneous Dissolution Test of Zidovudine - Lamivudine Tablets.
Topics: Anti-HIV Agents; Drug Combinations; Lamivudine; Least-Squares Analysis; Principal Component Analysis; Reverse Transcriptase Inhibitors; Solubility; Tablets; Zidovudine | 2015 |
Adverse events and adherence to HIV post-exposure prophylaxis: a cohort study at the Korle-Bu Teaching Hospital in Accra, Ghana.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Drug Combinations; Female; Ghana; HIV Infections; Hospitals, Teaching; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Middle Aged; Occupational Exposure; Post-Exposure Prophylaxis; Young Adult; Zidovudine | 2015 |
Pharmacokinetic Modeling of Lamivudine and Zidovudine Triphosphates Predicts Differential Pharmacokinetics in Seminal Mononuclear Cells and Peripheral Blood Mononuclear Cells.
Topics: Adult; Anti-HIV Agents; Biological Availability; Biological Transport; Blood Cells; Computer Simulation; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Models, Statistical; Semen; Thymine Nucleotides; Time Factors; Zidovudine | 2015 |
Prevalence of drug resistance mutations in HAART patients infected with HIV-1 CRF06_cpx in Estonia.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Estonia; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Prevalence; Reverse Transcriptase Inhibitors; Zidovudine | 2016 |
Photolysis of three antiviral drugs acyclovir, zidovudine and lamivudine in surface freshwater and seawater.
Topics: Acyclovir; Antiviral Agents; Fresh Water; Lamivudine; Models, Theoretical; Nitrates; Oxidation-Reduction; Photolysis; Risk Assessment; Seawater; Sunlight; Water Pollutants, Chemical; Zidovudine | 2015 |
Longitudinal Analysis of Adherence to First-Line Antiretroviral Therapy: Evidence of Treatment Sustainability from an Indian HIV Cohort.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Female; HIV Infections; Humans; India; Lamivudine; Longitudinal Studies; Male; Medication Adherence; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2016 |
Role of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine.
Topics: Acridines; Animals; Anti-HIV Agents; ATP-Binding Cassette Transporters; Dogs; Drug Interactions; Female; In Vitro Techniques; Indomethacin; Lamivudine; Madin Darby Canine Kidney Cells; Multidrug Resistance-Associated Protein 2; Placenta; Pregnancy; Rats, Wistar; Tetrahydroisoquinolines; Zidovudine | 2016 |
Which Clinician Questions Elicit Accurate Disclosure of Antiretroviral Non-adherence When Talking to Patients?
Topics: Adult; Anti-HIV Agents; Attitude of Health Personnel; Communication; Disclosure; Drug Combinations; Female; HIV Infections; Humans; Interviews as Topic; Lamivudine; Male; Medication Adherence; Middle Aged; Office Visits; Patient Care; Physician-Patient Relations; Zidovudine | 2016 |
Effect of abacavir on sustained virologic response to HCV treatment in HIV/HCV co-infected patients, Cohere in Eurocoord.
Topics: Adult; Anti-HIV Agents; Cohort Studies; Coinfection; Dideoxynucleosides; Drug Combinations; Emtricitabine; Europe; Female; Hepacivirus; Hepatitis C; HIV Infections; Humans; Interferon-alpha; Lamivudine; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribavirin; Tenofovir; Zidovudine | 2015 |
Adherence to Post-Exposure Prophylaxis (PEP) and Incidence of HIV Seroconversion in a Major North American Cohort.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV Seropositivity; Humans; Incidence; Lamivudine; Lopinavir; Male; Medication Adherence; Middle Aged; Post-Exposure Prophylaxis; Quebec; Ritonavir; Tenofovir; Young Adult; Zidovudine | 2015 |
Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV-1 Infection.
Topics: Animals; Anti-HIV Agents; Dideoxynucleosides; Drug Therapy, Combination; Hep G2 Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mice; Nanogels; Polyethylene Glycols; Polyethyleneimine; Polylysine; Reverse Transcriptase Inhibitors; Zidovudine | 2015 |
Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-infected Patients Treated with Highly Active Antiretroviral Therapy (HAART).
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; Case-Control Studies; Cyclopropanes; DNA, Mitochondrial; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Lopinavir; Male; Middle Aged; Mitochondria; Nelfinavir; Predictive Value of Tests; Ritonavir; ROC Curve; Stavudine; Zidovudine | 2015 |
Low Prolactin and High 20-α-Hydroxysteroid Dehydrogenase Levels Contribute to Lower Progesterone Levels in HIV-Infected Pregnant Women Exposed to Protease Inhibitor-Based Combination Antiretroviral Therapy.
Topics: 20-alpha-Hydroxysteroid Dehydrogenase; Animals; Anti-HIV Agents; Cells, Cultured; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Mice; Mice, Inbred C57BL; Placenta; Pregnancy; Pregnancy Complications, Infectious; Progesterone; Prolactin; Ritonavir; Trophoblasts; Zidovudine | 2016 |
Improved pregnancy outcomes with increasing antiretroviral coverage in South Africa.
Topics: Adolescent; Adult; Anti-Retroviral Agents; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Care; South Africa; Stavudine; Young Adult; Zidovudine | 2016 |
Hyaluronic Acid-Based Biocompatible Supramolecular Assembly for Sustained Release of Antiretroviral Drug.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; beta-Cyclodextrins; Biocompatible Materials; Cells, Cultured; Delayed-Action Preparations; Drug Delivery Systems; HIV-1; Humans; Hyaluronic Acid; Lamivudine; Polylysine; Zidovudine | 2016 |
CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population.
Topics: Adult; Africa South of the Sahara; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Coinfection; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Rifampin; Tuberculosis; Viral Load; Zidovudine | 2016 |
Treatment of vitiligo with antiretroviral therapy in a child with HIV infection.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Drug Therapy, Combination; Follow-Up Studies; HIV-1; Humans; Lamivudine; Male; Nevirapine; Treatment Outcome; Vitiligo; Zidovudine | 2016 |
Zidovudine, abacavir and lamivudine increase the radiosensitivity of human esophageal squamous cancer cell lines.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Dideoxynucleosides; DNA Damage; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Lamivudine; Radiation Tolerance; Radiation-Sensitizing Agents; Telomerase; Telomere; Zidovudine | 2016 |
Theoretical and experimental studies of the stability of drug-drug interact.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Interactions; Drug Stability; Hydrogen Bonding; Lamivudine; Molecular Docking Simulation; Molecular Dynamics Simulation; Thermodynamics; Zidovudine | 2016 |
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Coinfection; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Ethiopia; Female; Genetic Variation; Genome, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Immune Evasion; Lamivudine; Male; Mutation; Stavudine; Viral Load; Zidovudine | 2017 |
Treatment Outcomes and Resistance Patterns of Children and Adolescents on Second-Line Antiretroviral Therapy in Asia.
Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Indonesia; Lamivudine; Male; Prospective Studies; Ritonavir; Thailand; Treatment Outcome; Vietnam; Viral Load; Zidovudine | 2016 |
Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.
Topics: Animals; Anti-HIV Agents; Bone Marrow Cells; Brain; Dideoxynucleosides; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Gestational Age; Heart; Lamivudine; Mitochondria; Mitochondria, Heart; Oxygen Consumption; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine | 2016 |
Improved Adherence to Antiretroviral Therapy Observed Among HIV-Infected Children Whose Caregivers had Positive Beliefs in Medicine in Sub-Saharan Africa.
Topics: Africa South of the Sahara; Alkynes; Anti-HIV Agents; Attitude to Health; Benzoxazines; Caregivers; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; Humans; Infant; Lamivudine; Linear Models; Logistic Models; Male; Medication Adherence; Multivariate Analysis; Nevirapine; Randomized Controlled Trials as Topic; Stavudine; Surveys and Questionnaires; Uganda; Zambia; Zidovudine | 2017 |
Genotoxic and Cytotoxic Effects of Antiretroviral Combinations in Mice Bone Marrow.
Topics: Animals; Antiretroviral Therapy, Highly Active; Bone Marrow; Comet Assay; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Lamivudine; Mice; Micronuclei, Chromosome-Defective; Tenofovir; Zidovudine | 2016 |
Survival Outcomes in a Pediatric Antiretroviral Treatment Cohort in Southern Malawi.
Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Dideoxynucleotides; Female; HIV Infections; HIV Wasting Syndrome; Humans; Infant; Lamivudine; Malawi; Male; Proportional Hazards Models; Retrospective Studies; Rural Population; Stavudine; Survival Analysis; Tuberculosis, Pulmonary; Zidovudine | 2016 |
Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus.
Topics: Animals; Anti-HIV Agents; Chlorocebus aethiops; Ebolavirus; Guinea Pigs; HeLa Cells; Hemorrhagic Fever, Ebola; Humans; Lamivudine; Macrophages; Pilot Projects; Vero Cells; Virus Replication; Zidovudine | 2016 |
Triple Drug Combination of Zidovudine, Efavirenz and Lamivudine Loaded Lactoferrin Nanoparticles: an Effective Nano First-Line Regimen for HIV Therapy.
Topics: Alkynes; Animals; Anti-Retroviral Agents; Benzoxazines; Cell Line, Tumor; Cyclopropanes; Drug Combinations; Female; Half-Life; HIV Infections; HIV-1; Humans; Lactoferrin; Lamivudine; Male; Nanoparticles; Rats; Rats, Wistar; Tissue Distribution; Zidovudine | 2017 |
Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Lamivudine; Lopinavir; Male; Nevirapine; Phylogeny; Ritonavir; Zidovudine | 2016 |
Antiretrovirals causing severe pre-eclampsia.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Delivery, Obstetric; Female; HIV Infections; Humans; Infant, Extremely Low Birth Weight; Infant, Newborn; Lamivudine; Nevirapine; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Infectious; Tenofovir; Zidovudine | 2016 |
Safety of zidovudine/lamivudine scored tablets in children with HIV infection in Europe and Thailand.
Topics: Anti-HIV Agents; Child; Europe; HIV Infections; Humans; Lamivudine; Tablets; Thailand; Zidovudine | 2017 |
Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa.
Topics: Adult; Africa South of the Sahara; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Polymerase Chain Reaction; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Thymidine; Treatment Failure; Viral Load; Zidovudine | 2017 |
Triple-drug antiretroviral therapy results in lower HIV maternal-fetal transmission rates but increased adverse effects compared with zidovudine alone.
Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy Complications, Infectious; Zidovudine | 2017 |
Modelling CD4 T Cell Recovery in Hepatitis C and HIV Co-infected Children Receiving Antiretroviral Therapy.
Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Cohort Studies; Coinfection; Drug Combinations; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Interferon-alpha; Lamivudine; Lopinavir; Male; Models, Immunological; Polyethylene Glycols; Recombinant Proteins; Recovery of Function; Ribavirin; Ritonavir; Time-to-Treatment; Zidovudine | 2017 |
Factors associated with loss to follow-up after occupational HIV exposure in Cape Town, South Africa: a retrospective cohort study.
Topics: Adult; Anti-HIV Agents; Emtricitabine; Female; Health Personnel; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Lost to Follow-Up; Male; Occupational Exposure; Post-Exposure Prophylaxis; Retrospective Studies; South Africa; Stavudine; Tenofovir; Young Adult; Zidovudine | 2017 |
On assessing bioequivalence and interchangeability between generics based on indirect comparisons.
Topics: Anti-HIV Agents; Antimalarials; Artemether; Artemisinins; Computer Simulation; Confidence Intervals; Drugs, Generic; Ethanolamines; Fluorenes; HIV Infections; Humans; Lamivudine; Lumefantrine; Malaria; Models, Statistical; Therapeutic Equivalency; Zidovudine | 2017 |
Multi-state models for the analysis of time-to-treatment modification among HIV patients under highly active antiretroviral therapy in Southwest Ethiopia.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Ethiopia; Female; HIV Infections; Humans; Lamivudine; Male; Models, Theoretical; Nevirapine; Pregnancy; Retrospective Studies; Stavudine; Tenofovir; Time-to-Treatment; Treatment Failure; Zidovudine | 2017 |
Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; Genotype; Heterocyclic Compounds, 3-Ring; HIV-1; Lamivudine; Lopinavir; Nelfinavir; Oxazines; Piperazines; Pyridones; Reverse Transcriptase Inhibitors; Ritonavir; Zidovudine | 2017 |
Efficacy and safety of switching from branded to generic antiretrovirals in virologically suppressed HIV-infected patients.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Patient Safety; Poisson Distribution; RNA, Viral; Treatment Outcome; Zidovudine | 2017 |
Accumulation of HIV-1 drug resistance in patients on a standard thymidine analogue-based first line antiretroviral therapy after virological failure: implications for the activity of next-line regimens from a longitudinal study in Mozambique.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Male; Mozambique; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Viral Load; Zidovudine | 2017 |
Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.
Topics: Anti-HIV Agents; Cell Line, Tumor; Endogenous Retroviruses; Genome, Viral; Humans; Integrase Inhibitors; Lamivudine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Reverse Transcription; Stavudine; Virus Replication; Zidovudine | 2017 |
Bullseye Retinopathy from Antiretroviral Therapy.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Humans; Lamivudine; Male; Middle Aged; Retinal Diseases; Reverse Transcriptase Inhibitors; Zidovudine | 2017 |
Concomitant AIDS cholangiopathy and Fanconi syndrome as complications of HIV in a single patient.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cholangitis; Fanconi Syndrome; Female; HIV Infections; Humans; Lamivudine; Middle Aged; Tenofovir; Zidovudine | 2017 |
Motives for change of first-line antiretroviral therapy regimens in an unselected cohort of HIV/AIDS patients at a major referral centre in South-west Cameroon.
Topics: Adult; Anti-HIV Agents; Cameroon; Cohort Studies; Cross-Sectional Studies; Drug Combinations; Drug Substitution; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Referral and Consultation; Stavudine; Zidovudine | 2017 |
Different Degrees of Immune Recovery Using Antiretroviral Regimens with Vonavir or Zidovudine/Lamivudine/Efavirenz in HIVPositive Patients Receiving First Line Treatment in Iran.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Immunity, Cellular; Iran; Lamivudine; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; Sex Factors; Time Factors; Zidovudine | 2018 |
Simultaneous quantification of four antiretroviral drugs in breast milk samples from HIV-positive women by an ultra-high performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; Calibration; Chromatography, High Pressure Liquid; Colostrum; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Milk, Human; Pregnancy; Pregnancy Complications, Infectious; Reference Standards; Reproducibility of Results; Ritonavir; Tandem Mass Spectrometry; Young Adult; Zidovudine | 2018 |
A prospective study of adverse events to antiretroviral therapy in HIV- infected adults in Ekiti State, Nigeria.
Topics: Abdominal Pain; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nausea; Nevirapine; Nigeria; Prospective Studies; Sleep Initiation and Maintenance Disorders; Tenofovir; Young Adult; Zidovudine | 2016 |
Antiretroviral treatment Long-Term (ALT) cohort: a prospective cohort of 10 years of ART-experienced patients in Uganda.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; RNA, Viral; Time; Uganda; Viral Load; Zidovudine | 2018 |
Comparison of adherence to generic multi-tablet regimens vs. brand multi-tablet and brand single-tablet regimens likely to incorporate generic antiretroviral drugs by breaking or not fixed-dose combinations in HIV-infected patients.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Drugs, Generic; Female; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Tablets; Viral Load; Zidovudine | 2018 |
Could antiretrovirals be treating EBV in MS? A case report.
Topics: Adult; Brain; Drug Combinations; Epstein-Barr Virus Infections; Fatigue; Female; Humans; Immunologic Factors; Lamivudine; Multiple Sclerosis, Relapsing-Remitting; Reverse Transcriptase Inhibitors; Zidovudine | 2018 |
One-by-one imprinting in two eccentric layers of hollow core-shells: Sequential electroanalysis of anti-HIV drugs.
Topics: Anti-HIV Agents; Biosensing Techniques; Electrochemical Techniques; Graphite; Humans; Lamivudine; Limit of Detection; Molecular Imprinting; Polymers; Zidovudine | 2018 |
Birth Outcomes for Pregnant Women with HIV Using Tenofovir-Emtricitabine.
Topics: Adult; Anti-HIV Agents; Cohort Studies; Disease Transmission, Infectious; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Infant, Low Birth Weight; Infant, Newborn; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Premature Birth; Risk; Ritonavir; Tenofovir; Zidovudine | 2018 |
Short Communication: Reduced Nevirapine Concentrations Among HIV-Positive Women Receiving Mefloquine for Intermittent Preventive Treatment for Malaria Control During Pregnancy.
Topics: Adult; Anti-HIV Agents; Antimalarials; Cross-Sectional Studies; Drug Interactions; Female; Fetal Blood; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Kenya; Lamivudine; Malaria; Mefloquine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Zidovudine | 2018 |
Assessment of complex genomic alterations induced by AZT, 3TC, and the combination AZT +3TC.
Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CHO Cells; Cricetulus; DNA Damage; Lamivudine; Mutagenesis; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 2020 |
Patterns of adverse drug reaction signals in NAFDAC pharmacovigilance activities from January to June 2015: safety of drug use in Nigeria.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Anti-HIV Agents; Child; Child, Preschool; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Pharmacovigilance; Sex Factors; Young Adult; Zidovudine | 2018 |
Zidovudine-Mediated Autophagy Inhibition Enhances Mitochondrial Toxicity in Muscle Cells.
Topics: Anti-HIV Agents; Autophagy; Cell Line; Cell Survival; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mitochondria; Muscle Cells; Reactive Oxygen Species; Reverse Transcriptase Inhibitors; Zidovudine | 2019 |
Toxicity and genotoxicity induced by abacavir antiretroviral medication alone or in combination with zidovudine and/or lamivudine in Drosophila melanogaster.
Topics: Animals; Anti-HIV Agents; Dideoxynucleosides; DNA Damage; Drosophila melanogaster; Drug Synergism; Lamivudine; Mutation; Recombination, Genetic; Zidovudine | 2019 |
Adherence, virological outcome, and drug resistance in Chinese HIV patients receiving first-line antiretroviral therapy from 2011 to 2015.
Topics: Adult; Anti-HIV Agents; China; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Retrospective Studies; Stavudine; Sustained Virologic Response; Tenofovir; Zidovudine | 2018 |
Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome
Topics: Autoimmune Diseases of the Nervous System; Cerebrovascular Circulation; Dideoxynucleosides; Drug Combinations; France; Gene Expression; Humans; Interferons; Lamivudine; Nervous System Malformations; Pilot Projects; Reverse Transcriptase Inhibitors; Zidovudine | 2018 |
Antiretroviral Drug Concentrations in Breastmilk, Maternal HIV Viral Load, and HIV Transmission to the Infant: Results From the BAN Study.
Topics: Adolescent; Adult; Anti-HIV Agents; Breast Feeding; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Middle Aged; Milk, Human; Pregnancy; Ritonavir; RNA, Viral; Viral Load; Young Adult; Zidovudine | 2019 |
Rates of HBV, HCV, HDV and HIV type 1 among pregnant women and HIV type 1 drug resistance-associated mutations in breastfeeding women on antiretroviral therapy.
Topics: Adolescent; Adult; Anti-HIV Agents; Breast Feeding; Cameroon; Coinfection; Drug Resistance, Viral; Female; Health Knowledge, Attitudes, Practice; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Vaccines; Hepatitis C; Hepatitis C Antibodies; Hepatitis D; HIV Seroprevalence; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Vaccination; Young Adult; Zidovudine | 2018 |
Risk of false conformity decisions of multicomponent items controlled by correlated measurement results due to the sharing of analytical steps.
Topics: Chromatography, High Pressure Liquid; Decision Making; Lamivudine; Monte Carlo Method; Tablets; Uncertainty; Zidovudine | 2019 |
Zidovudine, tenofovir or abacavir? Different adverse effect profiles.
Topics: Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2016 |
Rate of viral load change and adherence of HIV adult patients treated with Efavirenz or Nevirapine antiretroviral regimens at 24 and 48 weeks in Yaoundé, Cameroon: a longitudinal cohort study.
Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cameroon; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nevirapine; Patient Compliance; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine | 2019 |
Incidence and types of HIV-1 drug resistance mutation among patients failing first-line antiretroviral therapy.
Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Antiviral Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Stavudine; Tenofovir; Treatment Failure; Viral Load; Zidovudine | 2019 |
Neurodevelopmental effects of ante-partum and post-partum antiretroviral exposure in HIV-exposed and uninfected children versus HIV-unexposed and uninfected children in Uganda and Malawi: a prospective cohort study.
Topics: Anti-Retroviral Agents; Breast Feeding; Child, Preschool; Cohort Studies; Drug Combinations; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Malawi; Male; Post-Exposure Prophylaxis; Postpartum Period; Pre-Exposure Prophylaxis; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Ritonavir; Uganda; Zidovudine | 2019 |
Safety of 6-week Neonatal Triple-combination Antiretroviral Postexposure Prophylaxis in High-risk HIV-exposed Infants.
Topics: Anti-Retroviral Agents; Chemoprevention; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Post-Exposure Prophylaxis; Prospective Studies; Thailand; Treatment Outcome; Zidovudine | 2019 |
Effects of Highly Active Antiretroviral Therapy on Albuminuria in HIVinfected Persons.
Topics: Adolescent; Adult; Age Factors; Albuminuria; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; Glomerular Filtration Rate; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; Sex Factors; Tenofovir; Young Adult; Zidovudine | 2020 |
Trend of HIV transmitted drug resistance before and after implementation of HAART regimen restriction in the treatment of HIV-1 infected patients in southern Taiwan.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Prevalence; Reverse Transcriptase Inhibitors; Taiwan; Zidovudine | 2019 |
Formulation, Development and Scale-Up of Fixed-Dose Combination Tablets Containing Zidovudine, Lamivudine and Nevirapine.
Topics: Anti-HIV Agents; Drug Combinations; Drug Compounding; Drug Development; Drug Stability; Lamivudine; Nevirapine; Tablets; Technology, Pharmaceutical; Zidovudine | 2019 |
Zidovudine and Lamivudine as Potential Agents to Combat HIV-Associated Neurocognitive Disorder.
Topics: Animals; Anti-HIV Agents; Chromatography, Liquid; Female; HIV Infections; Injections, Intraperitoneal; Lamivudine; Neurocognitive Disorders; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution; Zidovudine | 2019 |
HIV Drug Resistance after Failure of 6 Month First-line Therapy in a Hospital: A Case Series.
Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Tenofovir; Treatment Failure; Viral Load; Zidovudine | 2019 |
Association of maternal antiretroviral use with microcephaly in children who are HIV-exposed but uninfected (SMARTT): a prospective cohort study.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Microcephaly; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Puerto Rico; Tenofovir; Young Adult; Zidovudine | 2020 |
Effects of dissolved organic matter derived from freshwater and seawater on photodegradation of three antiviral drugs.
Topics: Acyclovir; Antiviral Agents; Fresh Water; Humic Substances; Lamivudine; Photolysis; Seawater; Water Pollutants, Chemical; Zidovudine | 2020 |
Descriptive analysis of World Health Organization-recommended second-line antiretroviral treatment: A retrospective cohort data analysis.
Topics: Adult; Age Factors; CD4 Lymphocyte Count; Databases, Factual; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Lost to Follow-Up; Male; Medication Adherence; Middle Aged; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Sex Factors; Tenofovir; Treatment Failure; Viral Load; World Health Organization; Zidovudine | 2019 |
Safety and Efficacy of Starting Antiretroviral Therapy in the First Week of Life.
Topics: Anti-HIV Agents; Botswana; Child; Child, Preschool; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Zidovudine | 2021 |
Cryptococcal meningitis and immune reconstitution inflammatory syndrome in a pediatric patient with HIV after switching to second line antiretroviral therapy: a case report.
Topics: AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antifungal Agents; Antigens, Fungal; Benzoxazines; Child; Cryptococcus neoformans; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Female; Fluconazole; HIV; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Lopinavir; Meningitis, Cryptococcal; Ritonavir; Treatment Outcome; Viral Load; Zidovudine | 2020 |
Incidence and predictors of loss to follow up among adult HIV patients on antiretroviral therapy in University of Gondar Comprehensive Specialized Hospital: A competing risk regression modeling.
Topics: Adolescent; Adult; Ambulatory Care; Anti-Retroviral Agents; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Hospitals, Special; Humans; Incidence; Lamivudine; Lost to Follow-Up; Male; Nevirapine; Regression Analysis; Retrospective Studies; Risk Factors; Young Adult; Zidovudine | 2020 |
The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains.
Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Mutation Rate; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Virus Replication; Zidovudine | 2020 |
Antiretroviral Prophylaxis: A Digestive Complication to Know.
Topics: Anti-HIV Agents; Child; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Zidovudine | 2021 |
Influence of a herbal preparation on the pharmacokinetics of highly active antiretroviral therapy drugs in rats.
Topics: Alkynes; Animals; Benzoxazines; Cyclopropanes; Herb-Drug Interactions; Lamivudine; Male; Rats; Zidovudine | 2020 |
Simple thin layer chromatography-ultraviolet spectrophotometric method for quality assessment of binary fixed-dose-combinations of lamivudine/tenofovir disoproxil fumarate and lamivudine/zidovudine in tablet formulations.
Topics: Anti-HIV Agents; Chromatography, Thin Layer; Drug Combinations; Drug Compounding; Lamivudine; Molecular Structure; Spectrophotometry, Ultraviolet; Tablets; Tenofovir; Zidovudine | 2020 |
Perinatal Antiretroviral Intensification to Prevent Intrapartum HIV Transmission When Antenatal Antiretroviral Therapy Is Initiated Less Than 8 Weeks Before Delivery.
Topics: Adult; Anti-HIV Agents; Bayes Theorem; Drug Combinations; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mothers; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Thailand; Viral Load; Young Adult; Zidovudine | 2020 |
Movement disorder in a patient with Human Immunodeficiency Virus on an anti-retroviral therapy: A Case Report.
Topics: AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Benzoxazines; Blood-Brain Barrier; Brain Stem; Cerebellar Ataxia; Cerebellum; Cyclopropanes; Drug Substitution; Female; Gait Ataxia; HIV Infections; Humans; Lamivudine; Magnetic Resonance Imaging; Mesencephalon; Middle Aged; Neurodegenerative Diseases; Nystagmus, Pathologic; Panic Disorder; Pons; Postural Balance; Sensation Disorders; Tenofovir; Zidovudine | 2020 |
Assessment of lamivudine, zidovudine, lopinavir, and ritonavir plasma levels in HIV-positive pregnant women: Drug monitoring application to improve patient safety.
Topics: Adult; Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Female; HIV Seropositivity; Humans; Lamivudine; Lopinavir; Patient Safety; Pregnancy; Ritonavir; Tandem Mass Spectrometry; Viral Load; Zidovudine | 2020 |
Zidovudine and lamivudine reach higher concentrations in ventricular than in lumbar human cerebrospinal fluid.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; RNA, Viral; Spinal Puncture; Stavudine; Viral Load; Zidovudine | 2020 |
Importance of early identification of PrEP breakthrough infections in a generalized HIV epidemic: a case report from a PrEP demonstration project in South Africa.
Topics: Administration, Oral; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Resistance, Viral; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Epidemics; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Pre-Exposure Prophylaxis; Retrospective Studies; South Africa; Treatment Outcome; Viral Load; Young Adult; Zidovudine | 2020 |
Case report: one case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a normal CD4
Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Betacoronavirus; C-Reactive Protein; CD4 Lymphocyte Count; Chills; Coronavirus Infections; COVID-19; Cyclopropanes; Fatigue; Female; Fever; HIV; HIV Infections; Humans; Immunocompromised Host; Immunoglobulin M; Lamivudine; Middle Aged; Pandemics; Pharyngitis; Pneumonia, Viral; Real-Time Polymerase Chain Reaction; SARS-CoV-2; Sputum; Time Factors; Tomography, X-Ray Computed; Virus Shedding; Zidovudine | 2020 |
Effect of combination antiretroviral therapy on human immunodeficiency virus 1 specific antibody responses in subtype-C infected children.
Topics: Anti-HIV Agents; Antibodies, Neutralizing; Antibody-Dependent Cell Cytotoxicity; Antiretroviral Therapy, Highly Active; Child, Preschool; Cohort Studies; Dideoxynucleosides; Drug Combinations; HIV Antibodies; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Ritonavir; Viral Load; Zidovudine | 2020 |
Risk factors for delayed viral suppression on first-line antiretroviral therapy among persons living with HIV in Haiti, 2013-2017.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Female; Haiti; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Risk Factors; Viral Load; Young Adult; Zidovudine | 2020 |
Prevalence and evaluation of risk factors of anti-retroviral therapy failure among human immunodeficiency virus/acquired immune deficiency syndrome patients in North India.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; HIV; HIV Infections; Humans; India; Lamivudine; Male; Prevalence; Risk Factors; Viral Load; Zidovudine | 2021 |
In utero and peripartum antiretroviral exposure as predictor of cognition in 6- to 10-year-old HIV-exposed Ugandan children - a prospective cohort study.
Topics: Anti-HIV Agents; Child; Cognition; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Uganda; Zidovudine | 2021 |
A Combination of Amino Acid Mutations Leads to Resistance to Multiple Nucleoside Analogs in Reverse Transcriptases from HIV-1 Subtypes B and C.
Topics: Amino Acids; Anti-HIV Agents; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine | 2022 |
Nevirapine hair and plasma concentrations and HIV-1 viral suppression among HIV infected ante-partum and post-partum women attended in a mother and child prevention program in Maputo city, Mozambique.
Topics: Adolescent; Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Drug Combinations; Female; Hair; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Medication Adherence; Mozambique; Nevirapine; Postpartum Period; Pregnancy; Prospective Studies; Viral Load; Young Adult; Zidovudine | 2022 |
Developmental Disorder Probability Scores at 6-18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children.
Topics: Adolescent; Anti-HIV Agents; Anti-Retroviral Agents; Autism Spectrum Disorder; Child; Developmental Disabilities; Female; HIV Infections; Humans; Lamivudine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Probability; Uganda; Zidovudine | 2022 |
Patterns and prognosis of holding regimens for people living with HIV in Asian countries.
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Prognosis; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine | 2022 |
Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon.
Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cameroon; Chemical and Drug Induced Liver Injury; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Risk Factors; Young Adult; Zidovudine | 2022 |
Selective modulation of placental and fetal MDR transporters by chronic in utero exposure to NRTIs in Sprague-Dawley rats: Importance for fetoprotection.
Topics: Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Resistance, Multiple; Female; Fetus; Lamivudine; Neoplasm Proteins; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Zidovudine | 2022 |
Minimal Cross-resistance to Tenofovir in Children and Adolescents Failing ART Makes Them Eligible for Tenofovir-Lamivudine-Dolutegravir Treatment.
Topics: Adolescent; Anti-HIV Agents; Child; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Lamivudine; Oxazines; Piperazines; Protease Inhibitors; Pyridones; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 2022 |
Serum Interleukin-6 and Weight Loss in Antiretroviral-naïve and Antiretroviral-treated Patients with HIV/AIDS: Relationships and Predictors.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Emtricitabine; HIV Infections; Humans; Interleukin-6; Lamivudine; Middle Aged; Nevirapine; Tenofovir; Weight Loss; Zidovudine | 2022 |
Rate of virological failure and HIV-1 drug resistance among HIV-infected adolescents in routine follow-up on health facilities in Cameroon.
Topics: Adolescent; Anti-HIV Agents; Cameroon; Drug Resistance, Viral; Follow-Up Studies; Health Facilities; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nevirapine; Retrospective Studies; Viral Load; Zidovudine | 2022 |
Rapid simultaneous analysis of anti human immunodeficiency virus drugs in pharmaceutical formulation by smart spectrophotometry based on multivariate calibration and least squares support vector machine methods.
Topics: Calibration; Drug Compounding; HIV; Lamivudine; Least-Squares Analysis; Spectrophotometry; Support Vector Machine; Zidovudine | 2023 |
Growth differences by school-age and adolescence according to in utero and peripartum antiretroviral therapy exposure among Ugandan children.
Topics: Adolescent; Anti-HIV Agents; Anti-Retroviral Agents; Child; Cohort Studies; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Uganda; Zidovudine | 2023 |
Short-term toxicity assessment of combined use of zidovudine, lamivudine and lopinavir/ritonavir in vitro and in vivo.
Topics: Animals; Anti-HIV Agents; Female; HIV Infections; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Male; Mammals; Mice; Rats; Ritonavir; Zidovudine | 2023 |
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket.
Topics: Anti-HIV Agents; Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication | 2016 |
1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus.
Topics: Animals; Antiviral Agents; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; HIV-1; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Uracil | 2016 |
Exploiting the hydrophobic channel of the NNIBP: Discovery of novel diarylpyrimidines as HIV-1 NNRTIs against wild-type and K103N mutant viruses.
Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2021 |