Page last updated: 2024-08-24

lamivudine and zidovudine

lamivudine has been researched along with zidovudine in 1507 studies

Research

Studies (1,507)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's429 (28.47)18.2507
2000's715 (47.45)29.6817
2010's316 (20.97)24.3611
2020's47 (3.12)2.80

Authors

AuthorsStudies
Beach, JW; Choi, BG; Chu, CK; Chun, MW; Chung, WK; Jeong, LS; Kim, HO; Nampalli, S; Schinazi, RF; Shanmuganathan, K1
Alves, AJ; Beach, JW; Chu, CK; Jeong, LS; Kim, HO; Mathis, R; McMillan, A; Nampalli, S; Schinazi, RF; Shanmuganathan, K1
Cha, SH; Endou, H; Kanai, Y; Kimura, M; Sekine, T; Tsuda, M; Wada, S1
Bader, JP; Cragg, GM; Newman, DJ; Yang, SS1
Gochfeld, DJ; Hamann, MT1
D'Aquila, RT; De Pasquale, MP; Olson, DP; Scadden, DT1
Choi, Y; Chong, Y; Choo, H; Chu, CK; Mathew, J; Schinazi, RF1
Akiyama, S; Baba, M; Furukawa, T; Nitanda, T; Okamoto, M; Sugimoto, Y; Wang, X1
Chong, Y; Chu, CK; Gumina, G; Mathew, JS; Schinazi, RF1
Chong, Y; Choo, H; Chu, CK; Mathews, J; Schinazi, RF; Zhu, W1
Chong, Y; Chu, CK; Gumina, G; Schinazi, RF; Wang, J; Zhou, W1
Cheng, YC; Drach, JC; Gullen, E; Kern, ER; Matsumi, S; Mitsuya, H; Zemlicka, J; Zhou, S1
Bennett, M; Chu, CK; Jin, Y; Rapp, KL; Schinazi, RF; Wang, J1
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Cheng, YC; Drach, JC; Gullen, E; Kern, ER; Mitsuya, H; Tamiya, S; Zemlicka, J; Zhou, S1
Baba, M; De Clercq, E; Shi, M; Takao, S; Wang, X1
Capparelli, E; Flynn, PM; Heckman, B; Knapp, KM; Lindsey, JC; Martinez, J; McNamara, J; Robbins, B; Rodman, J; Rodriguez, JF; Serchuck, L1
Andricopulo, AD; Moda, TL; Montanari, CA1
Ainsworth, J; Booth, C; Bradshaw, D; Geretti, AM; Malik, S; Pattery, T; Van Houtte, M; Waters, A1
Anderson, DJ; Gottlieb, GS; Preston, BD; Pyrak, CL; Smith, RA1
Beadle, JR; Bradley, M; Farasati, NA; Hostetler, KY; Huang, Y; Meier, C; Randhawa, P; Sauerbrei, A; Zemlicka, J1
Colonno, R; Dicker, I; Fan, L; Gali, V; Higley, H; Krystal, M; Lin, PF; Nowicka-Sans, B; Parkin, N; Tenney, D; Terry, B; Wang, C; Zhang, S1
Chen, JJ; Cheng, P; Jiang, ZY; Ma, YB; Yan, MH; Yang, LM; Zhang, FX; Zhang, XM; Zheng, YT1
Lombardo, F; Obach, RS; Waters, NJ1
Haas, RH; Naviaux, RK; Saitoh, A; Salva, NG; Spector, SA; Wong, JK1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Bachmann, MH; Fessel, WJ; Kagan, RM; Mitsuya, Y; Shafer, RW; Shahriar, R; Varghese, V1
Chen, YC; Dumond, JB; Fiscus, SA; Horton, AL; Kashuba, AD; Patterson, KB; Rezk, NL; Tappouni, HL; Tien, HC; Vourvahis, M; Yeh, RF1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N1
Baba, M; Cheng, YC; Dutschman, GE; Grill, SP; Hamasaki, T; Paintsil, E; Tanaka, H; Wang, CJ; Wang, J; Yang, G1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Almond, MR; Buckheit, RW; Hartman, T; Keilholz, L; Lampert, BM; Lanier, ER; Mankowski, MK; Osterling, MC; Painter, GR; Ptak, RG1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Balestrieri, E; Chiacchio, MA; Ferlazzo, A; Giofrè, SV; Iannazzo, D; Macchi, B; Mastino, A; Piperno, A; Pizzimenti, F; Romeo, R1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Bassit, L; Coats, SJ; Detorio, M; Herman, BD; Mellors, JW; Nettles, JH; Obikhod, A; Schinazi, RF; Sluis-Cremer, N; Solomon, S; Tao, SJ; Zhang, HW1
Hamburger, M; Hamy, F; Klimkait, T; Louvel, S; Mojarrab, M; Potterat, O; Sanglier, JJ; Vidal, V1
Agarwal, HK; Chhikara, BS; Doncel, GF; Parang, K; Quiterio, M1
Agarwal, HK; Buckheit, KW; Buckheit, RW; Parang, K1
Chavre, SN; Chu, CK; Govindarajan, R; Hung, W; Korba, B; Rawal, RK; Singh, US; Sugiyama, M; Tanaka, Y; Wang, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Balzarini, J; Bourdin, C; Chamberlain, S; Derudas, M; Hamon, N; Hinsinger, K; Introini, A; Kandil, S; Kolykhalov, A; Madela, K; Margolis, L; McGuigan, C; Meneghesso, S; Pertusati, F; Serpi, M; Slusarczyk, M; Vanpouille, C; Vernachio, J1
Chen, FE; Chen, WX; De Clercq, E; He, QQ; Pannecouque, C; Piao, HR; Wu, HQ; Wu, Y; Yan, ZH1
Costa, J; Dumontet, V; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Retailleau, P; Roussi, F1
Balzarini, J; Chen, F; Chen, W; De Clercq, E; Liu, Y; Meng, G; Pannecouque, C; Zheng, A1
Chen, W; De Clercq, E; Liu, X; Liu, Z; Pannecouque, C; Zhan, P1
Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yao, J1
Balzarini, J; Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Yu, M; Zhan, P1
Ashok, P; Balzarini, J; Chander, S; Murugesan, S; Pannecouque, C1
Chen, W; De Clercq, E; Fu, L; Huang, B; Li, C; Li, X; Liang, X; Liu, H; Liu, T; Liu, X; Pannecouque, C; Sun, Y; Zhan, P1
Girard-Valenciennes, E; Grondin, I; Leyssen, P; Litaudon, M; Neyts, J; Olivon, F; Palenzuela, H; Pannecouque, C; Roussi, F1
Arumugam, SR; Badri, KR; He, JJ; Visalli, RJ; Zhang, X; Zhao, H; Ziobrowski, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gray, LR; Hammarskjold, ML; Rekosh, D; Santos, WL; Tebit, DM; Wynn, JE; Zhang, W1
Bhatt, HG; Pannecouque, C; Patel, BD; Patel, SB1
Chen, W; Daelemans, D; De Clercq, E; Huang, B; Liu, X; Pannecouque, C; Yang, J; Zhan, P1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Daelemans, D; De Clercq, E; Ding, X; Fang, Z; Huang, B; Kang, D; Li, Z; Liu, X; Lu, X; Pannecouque, C; Xu, H; Zhan, P; Zhang, H; Zhou, Z1
Agarwal, HK; Chhikara, BS; Doncel, GF; Parang, K1
Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R1
Chen, FE; Gu, SX; Liu, GY; Meng, G; Pannecouque, C; Tang, JF; Wu, FS; Xiao, T; Xu, ZQ; Zhu, YY1
Cherukupalli, S; De Clercq, E; Feng, D; Fu, Z; Jiang, X; Kang, D; Liu, X; Pannecouque, C; Wang, Z; Zhan, P1
De Clercq, E; Huang, B; Jiang, X; Kang, D; Li, J; Liu, X; Olotu, FA; Pannecouque, C; Soliman, MES; Wang, Z; Zhan, P1
Chen, FE; De Clercq, E; Jin, X; Pannecouque, C; Piao, HR; Zhuang, C1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Cannon, D; Furman, PA; Lloyd, RM; Mathis, R; McMillan, A; Peck, A; Schinazi, RF; Sommadossi, JP; St Clair, M; Wilson, J1
Boehme, RE; Cameron, JM; Cammack, N; Coates, JA; Marr, CL; Penn, CR; Reid, PJ; Rouse, P1
Beach, JW; Cannon, D; Choi, WB; Chu, CK; Jeong, LS; Mathis, R; McMillan, A; Peck, A; Schinazi, RF; Yeola, S1
Cameron, JM; Cammack, N; Coates, JA; Jenkinson, HJ; Jowett, AJ; Jowett, MI; Pearson, BA; Penn, CR; Rouse, PL; Viner, KC1
Gao, Q; Li, XG; Parniak, MA; Rooke, R; Soudeyns, H; Tremblay, M; Wainberg, MA; Yao, XJ1
Belleau, B; Gao, Q; Kraus, JL; Nguyen-Ba, N; Soudeyns, H; Spira, B; Wainberg, MA; Yao, XI1
Portegies, P1
Benoit, SL; Eron, JJ; Fallon, MA; Jemsek, J; Kuritzkes, DR; MacArthur, RD; Quinn, JB; Rubin, M; Santana, J1
Merigan, TC1
Mitsuya, H1
Cameron, J; Fang, H; Gao, Q; Goldberg, E; Gu, Z; Parniak, MA; Salomon, H; Wainberg, MA1
Belmonte, A; Gelfand, M; Gu, Z; Nguyen, K; Salomon, H; Wainberg, MA1
Beardsley, T2
Harrigan, PR; Kemp, SD; Larder, BA1
Barry, DW; Pennington, KN; Rooney, J; St Clair, MH1
Faust, EA; Gao, Q; Gu, Z; Wainberg, MA1
Gunnarsson, G; Hammer, SM1
Kemp, SD; Larder, BA; Parry, NR; Tisdale, M1
Dudley, MN1
Cohen, J3
Balzarini, J1
Costigliola, P; Degrassi, A; Facchini, A; Lisignoli, G; Monaco, MC; Ricchi, E; Toneguzzi, S1
Arts, EJ; Boulerice, F; Geleziunas, R; Goldman, H; Wainberg, MA1
Arts, EJ; Gu, Z; Le Grice, SF; Marois, JP; Wainberg, MA1
Brenner, B; Lalonde, R; Mercure, L; Phaneuf, D; Wainberg, MA1
Hui, F; Kavlick, MF; Kojima, E; Mitsuya, H; Pluda, JM; Shirasaka, T; Yarchoan, R1
Gataric, N; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Schechter, MT; Yip, B1
Staszewski, S3
Danner, SA; Dellarnonica, P; Harrigan, PR; Hill, AM; Johnson, MA; Loveday, C; McDade, H; Picazo, JJ; Skinhøj, P; Staszewski, S; Verity, L1
Clumeck, N; Hill, AM; Ingrand, D; Johnson, M; Katlama, C; Loveday, C; Mallolas, J; McDade, H; Pearce, G; Staszewski, S1
Bartlett, JA; Benoit, SL; Ehmann, WC; Fallon, MA; Johnson, VA; Quinn, JB; Rubin, M; Self, PL; Sepulveda, GE; Tsoukas, C1
Rowe, PM1
Costes, O; Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C1
Bloor, S; Harrigan, PR; Kemp, SD; Kinghorn, I; Kohli, A; Larder, BA; Nájera, I1
Andries, K; De Brabander, M; De Crée, J; De Raeymaeker, M; Miller, V; Moeremans, M; Pearce, G; Peeters, M; Rehmet, S; Stark, T; Staszewski, S; Stoffels, P; Van den Broeck, R; Verbiest, W1
Back, DJ; Barry, MG; Hoggard, PG; Khoo, S; Veal, GJ1
Gerberding, JL1
Costes, O; Djediouane, A; Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C1
Chikami, GK; Piazza-Hepp, TD; Styrt, BA1
Lane, HC; Masur, H; Spooner, KM1
Coen, DM1
Bartlett, JA; Eron, JJ; Hill, AM; Johnson, J; Phillips, AN; Price, S; Rubin, M; Self, P1
Bakhtiari, M; Benoit, SL; Eron, JJ; Fallon, MA; Griffin, A; Kuritzkes, DR; Poticha, D; Quinn, JB; Rubin, M; Shugarts, DL1
Slavkin, HC1
Faulds, D; Lea, AP1
Schattner, A1
Cameron, JM; Cammack, N; Goulden, MG; Hopewell, PL; Penn, CR1
Mörike, EM1
Carr, A; Cooper, DA; Emery, S; Kelleher, A; Law, M1
Balagué, M; Cabrera, C; Clotet, B; De Clercq, E; Martínez-Picado, J; Puig, T; Romeu, J; Ruiz, L; Schmit, JC; Segura, A; Sirera, G; Tural, C; Vandamme, AM1
Boucher, CA; De Boer, RJ; De Jong, MD; Schuurman, R; Stilianakis, NI; Van Leeuwen, R1
Berkhout, B; Boucher, C; Keulen, W; Nijhuis, M; Schuurman, R1
Patrick, DM1
Cox, S; Palmer, S1
Bartlett, J; Eron, J; Gilbert, C; Hill, AM; Johnson, J; Johnson, VA; Keller, A; Kuritzkes, DR; Phillips, AN1
Lafeuillade, A; Pellegrino, P; Poggi, C; Profizi, N; Sayada, C1
Back, D; Barry, M; Gibbons, S; Merry, C; Mulcahy, F1
Eron, JJ1
Stephenson, J1
Belohradsky, BH; Eberle, J; Gürtler, L; Notheis, G; Sölder, B; Wintergerst, U1
Aguirrebengoa, K; Mallolas, J; Torres Tortosa, M; Uriz, J1
Bonhoeffer, S; Coffin, JM; Nowak, MA1
Bawdon, RE; Bloom, SL; Dias, KM; Gilstrap, LC1
Macready, N1
Baba, M; Nakade, K; Piras, G; Yuasa, S1
Bartlett, J; Eron, JJ; Hill, AM; Johnson, J; Katlama, C; McDade, H; Sawyer, W; Staszewski, S1
Hirschel, B; Rutschmann, O1
Back, DJ; Barry, MG; Khoo, SH; Veal, GJ1
Boulton, A1
Heins, JR1
Iversen, AK; Merigan, TC; Shafer, RW; Winters, MA1
Costes, O; Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C; Tourres, C1
Cavert, W; Danner, SA; Gebhard, K; Goudsmit, J; Haase, AT; Henry, K; McDade, H; Mills, R; Notermans, DW; Schuwirth, CM; Staskus, K; Wietgrefe, SW; Zhang, ZQ; Zupancic, M1
Cao, Y; Essunger, P; Ho, DD; Hurley, A; Markowitz, M; Perelson, AS; Saksela, K; Vesanen, M1
Costello, CE; Nelson, MR; Walsh, JC1
Ohta, Y; Shinkai, I1
Jacobson, MA; O'Donnell, JJ; Owens, S; Pavan, PR; Pollard, R; Rao, N; Sattler, F; Zegans, M1
Eisen, JA; Katzenstein, DA; Merigan, TC; Shafer, RW1
Fantini, J; Lafeuillade, A; Poggi, C; Tamalet, C; Yahi, N1
Wainberg, MA1
Bader, JP; Buckheit, RW; Gussio, R; Pallansch, L; Pattabiraman, N; Yang, SS1
Ahle, D; Bushnell, S; Chang, C; Collins, ML; Detmer, J; Fine, E; Ho, DD; Horn, T; Irvine, B; Kolberg, J; Shen, LP; Tyner, D; Urdea, MS; Zayati, C1
Böhler, T; Debatin, KM; Geiss, M; Haas, J; Herr, I1
Boucher, CA; Danner, S; de Groot, T; de Jong, D; Keulen, W; Lange, J; Nijhuis, M; Schuurman, R; van Leeuwen, R1
Collins, DO; Sakamoto, A1
Goody, RS; Immendörfer, U; Krebs, R; Thrall, SH; Wöhrl, BM1
Clavel, F; Dupont, B; Fournier, S; Moulignier, A; Pialoux, G; Poveda, JD1
Chenoweth, CE; Gobetti, JP1
Balfour, HH; Chodakewitz, JA; Currier, JS; Demeter, LM; Deyton, LR; Eron, JJ; Feinberg, JE; Fischl, MA; Grimes, JM; Hammer, SM; Hughes, MD; Squires, KE1
Chodakewitz, JA; Emini, EA; Eron, JJ; Gonzalez, C; Gulick, RM; Havlir, D; Jonas, L; McMahon, D; Meibohm, A; Mellors, JW; Richman, DD; Valentine, FT1
Lafeuillade, A; Poggi, C; Profizi, N; Tamalet, C1
Bulgheroni, E; Citterio, P; d'Arminio-Monforte, A; De Pasquale, MP; Galli, M; Kurtagic, S; Milazzo, L; Rusconi, S1
Escribano Hernández, A1
Gómez-Cano, M; Holguín, A; Mas, A; Soriano, V; Villalba, N1
Back, DJ; Barry, MG; Hoggard, PG; Kewn, S; Veal, GJ1
Feingold, A; Meislich, D; Rudy, B; Rutstein, RM; Word, B1
Cottalorda, J; Lefbvre, JC; Mariani, R; Monpoux, F; Sirvent, N1
Emini, E; Günthard, HF; Haase, AT; Havlir, DV; Ignacio, CC; Kwok, S; Richman, DD; Wong, JK; Zhang, ZQ1
Balzarini, J; De Clercq, E; Kleim, JP; Pelemans, H; Riess, G; Roesner, M; Winkler, I2
Günthard, HF; Havlir, DV; Hezareh, M; Ignacio, CC; Richman, DD; Spina, CA; Wong, JK1
Böhlen, L; Braathen, LR; Furrer, H; Hurni, MA1
Baba, M; Makino, M; Piras, G1
Izopet, J; Marchou, B; Massip, P; Pasquier, C; Puel, J; Sandres, K; Tamalet, C1
Hauri, D; John, H; Müller, NJ; Opravil, M1
Gisslén, M; Hagberg, L; Norkrans, G; Svennerholm, B1
Alaeus, A; Albert, J; Cox, S; Palmer, S1
Goldstein, H; Katopodis, NF; Kim, A; Kollmann, TR; Pettoello-Mantovani, M; Raker, C; Wiltshire, H; Yurasov, S1
Edelstein, RE; Frenkel, LM; Manns-Arcuino, LA; Nickerson, DA; Tobe, VO1
Cavert, W; Danner, SA; de Jong, JJ; de Wolf, F; Foudraine, NA; Goodwin, C; Goudsmit, J; Jurriaans, S; Kauffmann, RH; Leonard, JM; McDade, H; Meenhorst, PL; Notermans, DW; Schuwirth, CM1
Chapanduka, ZC; Matchaba, PT1
Back, DJ; Barry, MG; Hoggard, PG; Manion, V1
Collins-Jones, TL; Davis, KF; Farley, JJ; Houck, DL; Rothman, MI; Tepper, VJ; Wachtel, RC1
Barton, S; Blaxhult, A; Clotet, B; Goebel, FD; Hirschel, B; Katlama, C; Lundgren, JD; Pedersen, C; Phillips, AN; Vella, S1
North, TW; Preston, BD; Remington, KM; Schinazi, RF; Smith, RA1
Guatelli, JC; Günthard, HF; Havlir, DV; Ignacio, CC; Richman, DD; Riggs, NL; Wong, JK1
Beuers, U; Mühlhöfer, A; Samtleben, W; Thoenes, GH; von Appen, K; Weiss, M1
Gómez-Cano, M; Soriano, V1
Conway, B; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Rhone, SA; Schechter, MT; Sherlock, C; Yip, B1
Hester, EK; Peacock, JE1
DeMasi, R; Hill, AM; Montaner, JS1
Adams, O; Horneff, G; Wahn, V1
Ortega-Larrocea, G; Rutzen, AR; Tanguilig, GG1
Koopmans, PP; ter Hofstede, HJ; van Haelst, UJ1
Boswell, SL1
Bloor, S; Harrigan, PR; Kemp, SD; Larder, BA; Mellors, JW; Shi, C1
Gray, CM; Merigan, TC; Schapiro, JM; Winters, MA1
Clement, JG; Pardridge, WM; Wu, D1
Bai, J; Daar, ES; Giorgi, JV; Hausner, MA; Majchrowicz, M; Tamaddon, M1
Burt, MS; Mills, RJ; Scott-Lennox, JA1
Bloor, S; de Béthune, MP; Harrigan, PR; Hertogs, K; Kemp, SD; Larder, BA; Miller, V; Pauwels, R; Phillips, A; Rottmann, C; Staszewski, S1
Stevens, TP; Watson, WJ; Weinberg, GA1
Blanchard, G; Blum, L; Calvo, F; Danne, O; Lebbé, C; Morel, P; Pellet, C; Vérola, O1
Bloor, S; de Béthune, MP; Gröschel, B; Harrigan, PR; Hertogs, K; Kemp, SD; Larder, BA; Miller, V; Pauwels, R; Staszewski, S; Stürmer, M1
Aboulker, JP; Batisse, D; Belec, L; Castiel, P; Gilquin, J; Gonzalez-Canali, G; Jayle, D; Karmochkine, M; Kazatchkine, MD; Piketty, C; Si Mohamed, A; Weiss, L1
Batisse, D; Belec, L; Karmochkine, M; Kazatchkine, MD; Piketty, C; Si Mohamed, A1
Duchatelle, V; Durand, F; Hermine, O; Karras, A; Rabian, C; Valla, D; Viard, JP; Zylberberg, H1
Kaiser, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Theisen, A1
Kahn, JG; Marseille, E; Saba, J1
Balis, FM; Brouwers, P; Deutsch, PJ; Jarosinski, PF; Ju, W; Mistry, G; Mueller, BU; Nelson, RP; Pizzo, PA; Sei, S; Sleasman, J; Smith, S; Steinberg, SM; Winchell, G; Wood, LV; Zeichner, S; Zwerski, S1
Dalod, M; Deschemin, JC; Dumon, B; Gomard, E; Harzic, M; Hoen, B; Levy, JP; Pellegrin, I; Sereni, D; Venet, A1
Chiozzi, MH; Connick, E; Fox, L; Kessler, H; Kotzin, BL; Kuritzkes, DR; Landay, A; Lederman, MM; Leonard, JM; Martinez, A; Roe, JD; Rousseau, F; Spritzler, J; St Clair, M; Wade, M1
Belohradsky, BH; Eberle, J; Gürtler, L; Hoffmann, F; Notheis, G; Petropoulou, T; Sölder, B; Wintergerst, U1
Jürgens, H; Pollmann, H; Richter, H1
Chodakewitz, JA; Condra, JH; Emini, EA; Eron, JJ; Gonzalez, C; Gulick, RM; Havlir, D; Holder, D; Isaacs, R; Jonas, L; McMahon, D; Meibohm, A; Mellors, JW; Richman, DD; Schleif, WA1
Clotet, B; Gómez-Cano, M; Leal, M; Pérez-Olmeda, M; Pineda, JA; Puig, T; Rubio, A; Ruiz, L; Soriano, V; Xaus, N; Zamora, L1
Frothingham, R1
Berrey, MM; Chun, TW; Corey, L; Engel, D; Fauci, AS; Shea, T1
Boeri, E; Carrera, P; Gianotti, N; Lazzarin, A; Tambussi, G1
Clotet, B; De Clercq, E; Desmyter, J; Puig, T; Rossau, R; Ruiz, L; Schmit, JC; Stuyver, L; Van Laethem, K; Vandamme, AM; Vanderlinden, I1
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Ebeshi, BU; Elei, S; Kashimawo, AJ; Orubu, S; Soyinka, JO; Vaikosen, EN1
Amzal, B; Cressey, TR; Jarupanich, T; Jourdain, G; Kanjanavikai, P; Klinbuayaem, V; Koetsawang, S; Lallemant, M; Le Coeur, S; Ngo-Giang-Huong, N; Rawangban, B; Sabsanong, P; Siriwachirachai, T; Sripan, P; Urien, S; Wanasiri, P1
Azmi, M; Baber, ZU; Badlani, S; Dodani, SK; Nasim, A; Sheerani, M1
Anthony, P; Best, BM; Cahn, P; Chakhtoura, N; Chokephaibulkit, K; Cressey, TR; de Lourdes B Teixeira, M; Essack, Z; Frenkel, LM; Fuller, TL; Gouvèa, MIS; Hennessy, R; João, EC; Laimon, L; Mathiba, R; Mirochnick, M; Mmbaga, BT; Moreira, LF; Morrison, RL; Ngocho, JS; Njau, BN; Pilotto, JHS; Prommas, S; Rolon, MJ; Shapiro, DE; Siberry, GK; Violari, A; Werarak, P1
Domínguez-Castro, M; Figueroa-Damián, R; Galindo-Sevilla, N; Hernández-Pineda, J; Irles, C; Jung-Cook, HH; Katende-Kyenda, NL; Ramírez-Ramírez, A; Romo-Yañéz, J1
Eggers, C; Hoetelmans, R; Läer, S1
Abdool Karim, Q; Dawood, H; Mansoor, LE; Matten, D; Naicker, CL; Naidoo, K; Singo, D; Williamson, C1
Jianwei, L; Menghua, W; Qinwei, Y; Xin, Z; Yu, Z1
Batra, H; Chawla, H; Das, BK; Hussain, AW; Kabra, SK; Katpara, S; Kumar, S; Lodha, R; Luthra, K; Singh, R; Singh, S1
Bae, J; Cook, RL; Delcher, C; Francois, K; Joseph, N; Pessoa-Brandão, L; Puttkammer, N; Rich, SN; Robin, E; Yaghjyan, L1
Aweeka, F; Bradford, S; Browning, R; Coletti, A; Costello, D; Graham, B; Hughes, E; Kamthunzi, P; Kawalazira, R; Mmbaga, BT; Moye, J; Musoke, P; Nathoo, K; Norman, J; Owor, M; Purdue, L; Reding, C; Tierney, C; Whalen, ME; Wiesner, L; Ziemba, L1
Basu, A; Biswas, A; Das, BK; Nischal, N; Soneja, M; Sood, R; Wig, N1
Boivin, MJ; Ezeamama, AE; Giordani, B; Musoke, PM; Sikorskii, A; Tuke, R; Zalwango, SK1
Benamor Teixeira, ML; Chakhtoura, N; Coombs, RW; Frenkel, LM; Fuller, TL; Gouvêa, MI; Hennessey, R; João, EC; Mirochnick, M; Morrison, RL; Shapiro, DE; Whitson, K1
Boyer, PL; Caplan, MR; Clark, P; Dewar, R; Ferris, AL; Hughes, SH; Johnson, A; Maldarelli, F; Mican, J; Rehm, CA; Sneller, MC1
Bhatt, N; Couto, A; Cuco, RM; Degomme, O; Juga, A; Loquiha, O; Meggi, B; Osman, N; Sevene, E; Sidat, M; Temermam, M; Vubil, A1
Egger, M; Goldstein, F; Hauser, A; Kouyos, RD; Reichmuth, ML; Riou, J; Wandeler, G1
Awadu, JE; Coventry, A; Ezeamama, AE; Giordani, B; Sikorskii, A; Zalwango, S1
Avihingsanon, A; Azwa, I; Chaiwarith, R; Chan, YJ; Choi, JY; Ditangco, R; Do, CD; Gani, YM; Huy, BV; Jiamsakul, A; Khusuwan, S; Kiertiburanakul, S; Kim, JH; Kumarasamy, N; Lee, MP; Ly, PS; Merati, TP; Ng, OT; Pujari, S; Ross, J; Tanuma, J; Yunihastuti, E; Zhang, F1
Asienzo, J; Ategeka, G; Balyegisawa, A; Borok, M; Castelnuovo, B; Hoppe, A; Kaimal, A; Kambugu, A; Kiragga, A; Kityo, C; Lugemwa, A; Mirembe, G; Mugerwa, H; Musaazi, J; Odongpiny, ELA; Paton, NI; Siika, A; Walimbwa, S1
Ahmed, FO; Aning, BD; Ansah, RO; Ayisi-Boateng, NK; Enimil, AK; Ojuang, DA; Okeke, CB; Opoku, S; Sakyi, SA; Sarfo, AD; Senu, E; Wekesa, DN1
Bhattacharya, D; Butler, K; Chakhtoura, N; Currier, JS; Dula, D; Fowler, MG; George, K; Govender, V; Kiweewa, FM; Mohtashemi, N; Moodley, D; Musoke, P; Peters, MG; Ship, H; Tierney, C; Vhembo, T1
Abongwa, LE; Bella, S; Charles, F; Domkam, I; Emmanuel, N; Eyongetah, M; Jude, B; Moungang, EC; Mua, FH; Ngum, V; Nyamache, AK; Okemo, P; Tamboh, TC; Torimiro, J1
Copello, GJ; De Fino, FT; Filia, MF; Minoia, JM; Peroni, RN; Roma, MI1
Evans, D; Hans, L; Levin, L; Steegen, K; Technau, KG1
Adebisi, SA; Adedeji, NO; Adedeji, TA; Ajeigbe, AK; Ajose, AO; Akande, AA; Fawale, MB; Jeje, OA; Okesina, BA; Smith, OS1
Aghokeng, A; Ateba Ndongo, F; Bilong, S; Djeuda, ABD; Eboumbou Moukoko, CE; Eyoum Bille, B; Fokam, J; Grace, N; Koki Ndombo, P; Moukoko Mbonjo, M; Ndjolo, A; Penda, CI1
Motiee, F; Sohrabi, MR; Valaee, M1
Awadu, JE; Bovin, MJ; Ezeamama, AE; Giordani, B; Musoke, PM; Sikorskii, A; Zalwango, SK1
Chen, H; Deng, Y; Gao, Y; Ge, X; Ge, Y; Lan, G; Li, B; Li, S; Liu, S; Luo, H; Luo, L; Meng, Q; Qin, G; Qin, H; Wang, Y; Wen, P; Wu, X; Yang, H; Zhu, J; Zhu, Q1
Eleje, GU; Ikechebelu, JI; Nwagha, UI; Okafor, HU; Ugwu, AO; Ugwu, EO; Umeh, UA1
Chen, X; Daelemans, D; De Clercq, E; Huang, B; Kang, D; Li, W; Liu, X; Meng, Q; Pannecouque, C; Zhan, P1
Chizhov, AO; Geisman, AN; Khandazhinskaya, AL; Kochetkov, SN; Naesens, L; Novikov, MS; Ozerov, AA; Pannecouque, C; Seley-Radtke, KL; Valuev-Elliston, VT1
Cherukupalli, S; De Clercq, E; Fu, Z; Gao, S; Kang, D; Liu, X; Pannecouque, C; Sun, L; Zhan, P; Zhang, T; Zhou, Z1

Reviews

81 review(s) available for lamivudine and zidovudine

ArticleYear
Natural product-based anti-HIV drug discovery and development facilitated by the NCI developmental therapeutics program.
    Journal of natural products, 2001, Volume: 64, Issue:2

    Topics: Amino Acid Sequence; Anti-HIV Agents; HIV-1; Models, Biological; Models, Chemical; Molecular Sequence Data; National Institutes of Health (U.S.); Retrospective Studies; United States; Virus Replication

2001
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
An approach to antiretroviral treatment of HIV disease. Nucleoside monotherapy.
    Hospital practice (1995), 1995, Volume: 30 Suppl 1

    Topics: Antiviral Agents; Didanosine; HIV Infections; HIV-1; Humans; Lamivudine; Nucleosides; Stavudine; Zalcitabine; Zidovudine

1995
Clinical pharmacokinetics of nucleoside antiretroviral agents.
    The Journal of infectious diseases, 1995, Volume: 171 Suppl 2

    Topics: Animals; Didanosine; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1995
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.
    Pharmacy world & science : PWS, 1994, Apr-15, Volume: 16, Issue:2

    Topics: Animals; Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; Humans; Lamivudine; Purines; Pyrimidines; Retroviridae; Spiro Compounds; Stavudine; Thymidine; Uridine; Zalcitabine; Zidovudine

1994
Prophylaxis for occupational exposure to HIV.
    Annals of internal medicine, 1996, Sep-15, Volume: 125, Issue:6

    Topics: Antiviral Agents; Health Personnel; HIV Infections; Humans; Lamivudine; Occupational Exposure; Protease Inhibitors; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
Clinical toxicity of antiretroviral nucleoside analogs.
    Antiviral research, 1996, Volume: 31, Issue:3

    Topics: Animals; Antiviral Agents; Didanosine; Humans; Lamivudine; Mitochondria; Nucleosides; Stavudine; Zalcitabine; Zidovudine

1996
Guide to major clinical trials of antiretroviral therapy administered to patients infected with human immunodeficiency virus.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23, Issue:1

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Meta-Analysis as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1996
Wheel keeps turning for antiviral combination chemotherapy.
    Trends in microbiology, 1996, Volume: 4, Issue:2

    Topics: Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Lamivudine; Virus Diseases; Zidovudine

1996
Ritonavir.
    Drugs, 1996, Volume: 52, Issue:4

    Topics: Administration, Oral; Anti-HIV Agents; Biological Availability; CD4-Positive T-Lymphocytes; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Leukocyte Count; Randomized Controlled Trials as Topic; Ritonavir; RNA, Messenger; Zalcitabine; Zidovudine

1996
[Nucleoside analogs inhibiting reverse transcriptase: use in adult patient with HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14 Suppl 1

    Topics: Adult; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1996
Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments: a meta-analysis of controlled trials.
    AIDS (London, England), 1997, Mar-15, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Disease Progression; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; United States; Zidovudine

1997
Antiretroviral therapy: a guide to the most important trials.
    Schweizerische medizinische Wochenschrift, 1997, Mar-15, Volume: 127, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Viral Load; Zalcitabine; Zidovudine

1997
[Antiretroviral treatment and resistance].
    Revista clinica espanola, 1997, Volume: 197, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Drug Resistance, Microbial; HIV-1; Humans; Lamivudine; Mutation; Mycobacterium tuberculosis; Retroviridae Infections; Reverse Transcriptase Inhibitors; Zidovudine

1997
[Resistance to antiretroviral drugs].
    Medicina clinica, 1997, Oct-25, Volume: 109, Issue:14

    Topics: Antiviral Agents; Drug Resistance; Drug Resistance, Multiple; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nevirapine; Point Mutation; Retroviridae; Retroviridae Infections; Zidovudine

1997
Platelet dysfunction as the cause of spontaneous bleeding in two haemophilic patients taking HIV protease inhibitors.
    Thrombosis and haemostasis, 1998, Volume: 79, Issue:6

    Topics: Adolescent; Adult; Anti-HIV Agents; Hemophilia A; Hemorrhage; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Reverse Transcriptase Inhibitors; Zidovudine

1998
[Antiretroviral treatment in human immunodeficiency virus infection].
    Annales de dermatologie et de venereologie, 1997, Volume: 124, Issue:9

    Topics: Antiviral Agents; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Ritonavir; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine

1997
Antiretroviral chemotherapy.
    Current clinical topics in infectious diseases, 1998, Volume: 18

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1998
Toxicity of antiretroviral agents.
    The American journal of medicine, 1997, May-19, Volume: 102, Issue:5B

    Topics: Anti-HIV Agents; Didanosine; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1997
Prevalence and incidence of resistance to zidovudine and other antiretroviral drugs.
    The American journal of medicine, 1997, May-19, Volume: 102, Issue:5B

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Prevalence; Reverse Transcriptase Inhibitors; Risk Factors; Saquinavir; Stavudine; Time Factors; Zidovudine

1997
Combined treatment with zidovudine, lamivudine, nelfinavir and ganciclovir in an infant with human immunodeficiency virus type 1 infection and cytomegalovirus encephalitis: case report and review of the literature.
    The Pediatric infectious disease journal, 1999, Volume: 18, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cytomegalovirus Infections; Diseases in Twins; Drug Therapy, Combination; Encephalitis, Viral; Female; Ganciclovir; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lamivudine; Nelfinavir; Zidovudine

1999
HIV-associated pityriasis rubra pilaris responsive to triple antiretroviral therapy.
    The British journal of dermatology, 1999, Volume: 140, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Lamivudine; Pityriasis Rubra Pilaris; Saquinavir; Zidovudine

1999
Antiretrovirals.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine

1999
Review of NNRTIs: 'today and tomorrow'.
    International journal of clinical practice. Supplement, 1999, Volume: 103

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; Zidovudine

1999
Coming therapies: abacavir.
    International journal of clinical practice. Supplement, 1999, Volume: 103

    Topics: Anti-HIV Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Zidovudine

1999
Finding a role for zalcitabine in the HAART era.
    Antiviral therapy, 1998, Volume: 3, Issue:3

    Topics: Anti-HIV Agents; Drug Resistance; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Saquinavir; Zalcitabine; Zidovudine

1998
[Early treatment of sexual exposure to human immunodeficiency virus].
    Annales de dermatologie et de venereologie, 2000, Volume: 127, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Combinations; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Nelfinavir; Probability; Risk Factors; Sexual Behavior; Sexual Partners; Time Factors; Zidovudine

2000
Stavudine plus a non-thymidine nucleoside reverse transcriptase inhibitor as a backbone for highly active antiretroviral therapy.
    Antiviral therapy, 1998, Volume: 3 Suppl 4

    Topics: Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1998
Transgenic mice as a chemotherapeutic model for hepatitis B virus infection.
    Antiviral therapy, 1998, Volume: 3, Issue:Suppl 3

    Topics: Administration, Oral; Animals; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Genome, Viral; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B Virus, Woodchuck; Humans; Interferon-alpha; Lamivudine; Mice; Mice, Transgenic; Polymerase Chain Reaction; Sex Factors; Time Factors; Viral Load; Virus Replication; Zidovudine

1998
Intracellular studies of the nucleoside reverse transcriptase inhibitor active metabolites: a review.
    Puerto Rico health sciences journal, 2000, Volume: 19, Issue:1

    Topics: Adult; Aged; Anti-HIV Agents; Antimetabolites; Cells, Cultured; Child; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phosphates; Phosphorylation; Polyphosphates; Radioimmunoassay; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

2000
Mother-to-child HIV-1 transmission: state of the art and implications for public policy.
    Puerto Rico health sciences journal, 2000, Volume: 19, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Cesarean Section; Clinical Trials as Topic; Female; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Monitoring, Physiologic; Pregnancy; Pregnancy Complications, Infectious; Public Policy; Registries; Reverse Transcriptase Inhibitors; Risk Factors; RNA, Viral; Viral Load; Zidovudine

2000
Recurrence of the acute HIV syndrome after interruption of antiretroviral therapy in a patient with chronic HIV infection: A case report.
    Annals of internal medicine, 2000, Sep-19, Volume: 133, Issue:6

    Topics: Acute Disease; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Chronic Disease; Disease Progression; Drug Therapy, Combination; Fever; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Recurrence; Reverse Transcriptase Inhibitors; RNA, Viral; Syndrome; Viral Load; Zidovudine

2000
Occupational exposure to HIV and post-exposure prophylaxis in healthcare workers.
    Occupational medicine (Oxford, England), 2000, Volume: 50, Issue:6

    Topics: Anti-HIV Agents; Health Personnel; HIV Infections; HIV Seropositivity; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Exposure; Reverse Transcriptase Inhibitors; United Kingdom; Zidovudine

2000
Management of the infant born to a mother infected with human immunodeficiency virus type 1 (HIV-1): current concepts.
    American journal of perinatology, 2000, Volume: 17, Issue:8

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Zidovudine

2000
International perspectives on antiretroviral resistance. Nucleoside reverse transcriptase inhibitor resistance.
    Journal of acquired immune deficiency syndromes (1999), 2001, Mar-01, Volume: 26 Suppl 1

    Topics: Dideoxynucleosides; Disease Progression; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

2001
Anti-retroviral treatment in Nigeria: a review.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2000, Volume: 6, Issue:4

    Topics: Anti-HIV Agents; Clinical Trials as Topic; HIV Infections; Humans; Lamivudine; Nigeria; Zidovudine

2000
Primary biliary cirrhosis: new thoughts on pathophysiology and treatment.
    Current gastroenterology reports, 2002, Volume: 4, Issue:1

    Topics: Alkaline Phosphatase; Autoimmunity; DNA; Drug Combinations; Humans; Lamivudine; Liver; Liver Cirrhosis, Biliary; Pilot Projects; Retroviridae; Retroviridae Infections; Reverse Transcriptase Inhibitors; Zidovudine

2002
HIV vaccine evaluation center in Rio de Janeiro, Brazil.
    Vaccine, 2002, May-06, Volume: 20, Issue:15

    Topics: Adolescent; Adult; AIDS Vaccines; Anti-HIV Agents; Behavior Therapy; Bisexuality; Brazil; Clinical Trials, Phase II as Topic; Disease Transmission, Infectious; Enzyme-Linked Immunosorbent Assay; Follow-Up Studies; HIV Antibodies; HIV Envelope Protein gp120; HIV Infections; HIV Seropositivity; Homosexuality; Humans; Incidence; Lamivudine; Male; Middle Aged; Safety; Sensitivity and Specificity; Zidovudine

2002
Trizivir.
    Expert opinion on pharmacotherapy, 2002, Volume: 3, Issue:5

    Topics: Antiretroviral Therapy, Highly Active; Biological Availability; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; Drug Evaluation; HIV Infections; HIV-1; Humans; Intestinal Absorption; Lamivudine; Zidovudine

2002
[Complete auriculoventricular block in a patient treatment with Lopinavir/Ritonavir].
    Enfermedades infecciosas y microbiologia clinica, 2002, Volume: 20, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Aryl Hydrocarbon Hydroxylases; Bundle-Branch Block; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Inhibitors; Heart; Heart Block; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Oxidoreductases, N-Demethylating; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Syncope; Zidovudine

2002
Antiretroviral therapy-induced psychosis: case report and brief review of the literature.
    HIV medicine, 2003, Volume: 4, Issue:2

    Topics: Adult; Antipsychotic Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Female; Hallucinations; HIV Seropositivity; Humans; Lamivudine; Nevirapine; Psychoses, Substance-Induced; Zidovudine

2003
Effects of nucleoside-based antiretroviral chemotherapy on human T cell leukaemia/lymphotropic virus type 1 (HTLV-1) infection in vitro.
    The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:6

    Topics: Animals; Anti-Retroviral Agents; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Lamivudine; Nucleosides; Zidovudine

2003
Lamivudine/zidovudine/abacavir: triple combination tablet.
    Drugs, 2003, Volume: 63, Issue:11

    Topics: Administration, Oral; Anti-HIV Agents; Biological Availability; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine

2003
Where now for Trizivir? Role of the triple-NRTI pill post-ACTG 5095.
    The AIDS reader, 2003, Volume: 13, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Chemistry, Pharmaceutical; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Humans; Lamivudine; Patient Selection; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine

2003
The continuing evolution of HIV therapy.
    The AIDS reader, 2003, Volume: 13, Issue:12

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cyclopropanes; Delayed-Action Preparations; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Monitoring; Emtricitabine; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Oligopeptides; Organophosphates; Organophosphonates; Organophosphorus Compounds; Oxazines; Pyridines; Randomized Controlled Trials as Topic; Stavudine; Sulfonamides; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2003
Evolution of HIV-1-related conjunctival molluscum contagiosum under HAART: report of a bilaterally manifesting case and literature review.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2004, Volume: 242, Issue:11

    Topics: Adult; Antiretroviral Therapy, Highly Active; Conjunctival Diseases; Drug Combinations; Eye Infections, Viral; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Molluscum Contagiosum; Zidovudine

2004
Prognostic factors in lactic acidosis syndrome caused by nucleoside reverse transcriptase inhibitors: report of eight cases and review of the literature.
    AIDS patient care and STDs, 2004, Volume: 18, Issue:7

    Topics: Acidosis, Lactic; Adult; Didanosine; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; New York; Reverse Transcriptase Inhibitors; Stavudine; Syndrome; Zidovudine

2004
Antiretroviral therapy during pregnancy and early neonatal life: consequences for HIV-exposed, uninfected children.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2004, Volume: 8, Issue:2

    Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Zidovudine

2004
Nucleoside reverse transcriptase inhibitors, mitochondrial DNA and AIDS therapy.
    Antiviral therapy, 2005, Volume: 10 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; DNA Replication; DNA, Mitochondrial; Humans; Lamivudine; Mitochondria; Nucleosides; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2005
Piloting post-exposure prophylaxis in Kenya raises specific concerns for the management of childhood rape.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Body Weight; Child; Child Abuse, Sexual; Child, Preschool; Feasibility Studies; Female; HIV Infections; Humans; Infant; Kenya; Lamivudine; Male; Pilot Projects; Practice Guidelines as Topic; Rape; Risk Factors; Rural Health; Sexually Transmitted Diseases; Zidovudine

2006
Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa?
    AIDS (London, England), 2005, Nov-04, Volume: 19, Issue:16

    Topics: Adult; Anti-HIV Agents; Breast Feeding; Drug Combinations; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Perinatal Care; Randomized Controlled Trials as Topic; Regression Analysis; Risk Factors; Treatment Outcome; Zidovudine

2005
[The treatment of HIV infection].
    Presse medicale (Paris, France : 1983), 2005, Nov-19, Volume: 34, Issue:20 Pt 2

    Topics: Adenine; Anti-Retroviral Agents; Carbamates; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Therapy, Combination; Furans; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Sulfonamides; Tenofovir; Zidovudine

2005
Triple-nucleoside analog antiretroviral therapy: is there still a role in clinical practice? A review.
    MedGenMed : Medscape general medicine, 2005, Jun-02, Volume: 7, Issue:2

    Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prognosis; Treatment Outcome; Zidovudine

2005
Evidence behind the WHO guidelines: hospital care for children: what antiretroviral agents and regimens are effective in the prevention of mother-to-child transmission of HIV?
    Journal of tropical pediatrics, 2006, Volume: 52, Issue:4

    Topics: Anti-HIV Agents; Breast Feeding; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; World Health Organization; Zidovudine

2006
Evolving simplified treatment strategies for HIV infection: the role of a single-class quadruple-nucleoside/nucleotide regimen of trizivir and tenofovir.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:16

    Topics: Adenine; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2006
Computational models of antiviral toxicity.
    Current opinion in drug discovery & development, 2007, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Computer Simulation; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Molecular Structure; Stavudine; Zidovudine

2007
Abacavir sulfate/lamivudine/zidovudine fixed combination in the treatment of HIV infection.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Treatment Outcome; Zidovudine

2007
Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:3

    Topics: Anti-HIV Agents; Antimetabolites; Antiretroviral Therapy, Highly Active; Child; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Outcome; Zidovudine

2007
Quadruple nucleoside therapy with zidovudine, lamivudine, abacavir and tenofovir in the treatment of HIV.
    Antiviral therapy, 2007, Volume: 12, Issue:5

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine

2007
[Adipose tissue hypertrophy after Lipostructure in HIV patient with antiretroviral treatment. Case report and literature review].
    Annales de chirurgie plastique et esthetique, 2009, Volume: 54, Issue:4

    Topics: Adipose Tissue; Adult; Anti-Retroviral Agents; Drug Combinations; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Hypertrophy; Lamivudine; Male; Postoperative Complications; Zidovudine

2009
Non-occupational postexposure prophylaxis for HIV: a systematic review.
    Health technology assessment (Winchester, England), 2009, Volume: 13, Issue:14

    Topics: Anti-HIV Agents; Cost-Benefit Analysis; Databases, Bibliographic; Drug Combinations; Drug Therapy, Combination; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Lopinavir; Premedication; Pyrimidinones; Ritonavir; Substance Abuse, Intravenous; Time Factors; Treatment Outcome; Unsafe Sex; Zidovudine

2009
[The "induction-maintenance" strategy].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 16

    Topics: Adipose Tissue; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Viral Load; Virus Replication; Zidovudine

2008
A combination drug of abacavir-lamivudine-zidovudine (Trizivir) for treating HIV infection and AIDS.
    The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Drug Combinations; HIV Infections; Humans; Lamivudine; Nelfinavir; Oligopeptides; Pyridines; Randomized Controlled Trials as Topic; Zidovudine

2009
Tenofovir or zidovudine in three-drug combination therapy with one nucleoside reverse transcriptase inhibitor and one non-nucleoside reverse transcriptase inhibitor for initial treatment of HIV infection in antiretroviral-naïve individuals.
    The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2010
Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection.
    The Cochrane database of systematic reviews, 2011, Jul-06, Issue:7

    Topics: Anti-HIV Agents; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Zidovudine

2011
HIV-1-resistance-associated mutations after failure of first-line antiretroviral treatment among children in resource-poor regions: a systematic review.
    The Lancet. Infectious diseases, 2011, Volume: 11, Issue:10

    Topics: Adolescent; Africa; Alkynes; Anti-HIV Agents; Asia; Benzoxazines; Child; Child, Preschool; Cross-Sectional Studies; Cyclopropanes; Developing Countries; Drug Resistance, Viral; Female; Health Resources; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Latin America; Lopinavir; Male; Mutation; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Treatment Failure; Viral Load; Zidovudine

2011
Pharmacokinetics of antiretroviral drugs in anatomical sanctuary sites: the fetal compartment (placenta and amniotic fluid).
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Adenine; Adult; Amniotic Fluid; Anti-HIV Agents; Cyclohexanes; Enfuvirtide; Female; Fetal Blood; Fetus; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Maraviroc; Nevirapine; Organophosphonates; Peptide Fragments; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrrolidinones; Raltegravir Potassium; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Viral Load; Zidovudine

2011
Antiretrovirals for HIV Exposure Prophylaxis.
    Current medicinal chemistry, 2012, Volume: 19, Issue:35

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012
Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS.
    The Cochrane database of systematic reviews, 2013, Mar-28, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Nelfinavir; Oligopeptides; Pyridines; Randomized Controlled Trials as Topic; Zidovudine

2013
A randomized pahse I bioequivalence clinincal trial of a paediatric fixed-dose combination antiretroviral reconstitutable suspension in healthy adult volunteers.
    Antiviral therapy, 2013, Volume: 18, Issue:2

    Topics: Adult; Anti-HIV Agents; Cross-Over Studies; Drug Combinations; Female; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Therapeutic Equivalency; Young Adult; Zidovudine

2013
Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV.
    The Cochrane database of systematic reviews, 2013, Jun-05, Issue:6

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lipids; Maintenance Chemotherapy; Middle Aged; Nevirapine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Treatment Failure; Viral Load; Young Adult; Zidovudine

2013
Choice of antiretroviral drugs for postexposure prophylaxis for children: a systematic review.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Jun-01, Volume: 60 Suppl 3

    Topics: Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Nevirapine; Post-Exposure Prophylaxis; Pregnancy; Prospective Studies; Randomized Controlled Trials as Topic; Ritonavir; Zidovudine

2015
Combination antiretroviral studies for patients with primary biliary cirrhosis.
    World journal of gastroenterology, 2016, Jan-07, Volume: 22, Issue:1

    Topics: Animals; Anti-Retroviral Agents; Betaretrovirus; Clinical Trials as Topic; Drug Therapy, Combination; Emtricitabine; Humans; Lamivudine; Liver Cirrhosis, Biliary; Lopinavir; Mammary Tumor Virus, Mouse; Mice; Tenofovir; Zidovudine

2016
Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis.
    BMJ open, 2017, Sep-11, Volume: 7, Issue:9

    Topics: Adult; Anti-Retroviral Agents; Drug Combinations; Emtricitabine; Female; Hepatitis B; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Ritonavir; Tenofovir; Young Adult; Zidovudine

2017
Zidovudine/Lamivudine vs. Abacavir/Lamivudine vs. Tenofovir/Emtricitabine in fixed-dose combinations as initial treatment for HIV patients: a systematic review and network meta-analysis.
    Colombia medica (Cali, Colombia), 2017, Jun-30, Volume: 48, Issue:2

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Lamivudine; Network Meta-Analysis; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine

2017
Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Abnormalities, Drug-Induced; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Congenital Abnormalities; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Network Meta-Analysis; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Stavudine; Stillbirth; Zidovudine

2018
Regression of human immunodeficiency virus-associated oral Kaposi sarcoma with combined antiretroviral therapy: A case report and literature review.
    Head & neck, 2019, Volume: 41, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Combinations; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Mouth Neoplasms; Ritonavir; Sarcoma, Kaposi; Zidovudine

2019
Acquired HIV drug resistance mutations on first-line antiretroviral therapy in Southern Africa: Systematic review and Bayesian evidence synthesis.
    Journal of clinical epidemiology, 2022, Volume: 148

    Topics: Adult; Anti-Retroviral Agents; Bayes Theorem; Drug Resistance, Viral; Emtricitabine; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Tenofovir; Viral Load; Zidovudine

2022
Factors associated with viral suppression and rebound among adult HIV patients on treatment: a retrospective study in Ghana.
    AIDS research and therapy, 2022, 05-25, Volume: 19, Issue:1

    Topics: Adult; Anti-HIV Agents; Ghana; HIV Infections; Humans; Lamivudine; Nevirapine; Retrospective Studies; Viral Load; Zidovudine

2022
Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus.
    The Cochrane database of systematic reviews, 2023, 06-12, Volume: 6

    Topics: Antiviral Agents; Coinfection; DNA, Viral; Emtricitabine; Female; Hepatitis B e Antigens; Hepatitis B virus; HIV; HIV Infections; HIV Seropositivity; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnant Women; Ritonavir; Tenofovir; Zidovudine

2023

Trials

399 trial(s) available for lamivudine and zidovudine

ArticleYear
Intracellular pharmacokinetics of once versus twice daily zidovudine and lamivudine in adolescents.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10

    Topics: Adolescent; Adult; Anti-HIV Agents; Area Under Curve; CD4 Lymphocyte Count; Child; Cross-Over Studies; Drug Combinations; Female; Half-Life; Humans; Lamivudine; Male; Monocytes; Phosphorylation; Zidovudine

2007
Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. North American HIV Working Party.
    The New England journal of medicine, 1995, Dec-21, Volume: 333, Issue:25

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zalcitabine; Zidovudine

1995
Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy.
    Science (New York, N.Y.), 1995, Aug-04, Volume: 269, Issue:5224

    Topics: Antiviral Agents; Base Sequence; CD4 Lymphocyte Count; Cell Line; Codon; Drug Resistance, Microbial; Drug Therapy, Combination; HeLa Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Serial Passage; Zalcitabine; Zidovudine

1995
Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (--)-2',3'-dideoxy-3'-thiacytidine.
    Antiviral research, 1995, Volume: 28, Issue:2

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Resistance, Microbial; Genotype; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phenotype; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1995
Zidovudine and lamivudine: results of phase III studies.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Volume: 10 Suppl 1

    Topics: Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine

1995
Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group.
    JAMA, 1996, Jul-10, Volume: 276, Issue:2

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine

1996
Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group.
    JAMA, 1996, Jul-10, Volume: 276, Issue:2

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Zalcitabine; Zidovudine

1996
Lamivudine plus zidovudine compared with zalcitabine plus zidovudine in patients with HIV infection. A randomized, double-blind, placebo-controlled trial. North American HIV Working Party.
    Annals of internal medicine, 1996, Aug-01, Volume: 125, Issue:3

    Topics: Adult; Antiviral Agents; beta 2-Microglobulin; Biopterins; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Core Protein p24; HIV Infections; Humans; Lamivudine; Male; Neopterin; Polymerase Chain Reaction; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Outcome; Zalcitabine; Zidovudine

1996
Virological and immunological analysis of a triple combination pilot study with loviride, lamivudine and zidovudine in HIV-1-infected patients.
    AIDS (London, England), 1996, Volume: 10, Issue:5

    Topics: Acetamides; Acetophenones; Adult; Antiviral Agents; Case-Control Studies; CD4 Lymphocyte Count; Cross-Over Studies; DNA Mutational Analysis; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; Pilot Projects; RNA, Viral; Zalcitabine; Zidovudine

1996
HIV-1 RNA levels and the development of clinical disease. North American Lamivudine HIV Working Group.
    AIDS (London, England), 1996, Volume: 10, Issue:8

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Predictive Value of Tests; Proportional Hazards Models; RNA, Viral; Zidovudine

1996
Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients.
    AIDS (London, England), 1996, Volume: 10, Issue:9

    Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Genes, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Virus Replication; Zidovudine

1996
CD8+ lymphocyte responses to antiretroviral therapy of HIV infection.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1996, Dec-01, Volume: 13, Issue:4

    Topics: Acetamides; Acetophenones; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Lamivudine; Lymphocyte Count; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zalcitabine; Zidovudine

1996
Efficacy of triple combination therapy with zidovudine (ZDV) plus zalcitabine (ddC) plus lamivudine (3TC) versus double (ZDV+3TC) combination therapy in patients previously treated with ZDV+ddC.
    AIDS (London, England), 1996, Volume: 10, Issue:14

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Viral Load; Zalcitabine; Zidovudine

1996
The treatment of antiretroviral-naive subjects with the 3TC/zidovudine combination: a review of North American (NUCA 3001) and European (NUCB 3001) trials.
    AIDS (London, England), 1996, Volume: 10 Suppl 5

    Topics: Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Europe; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; North America; Viral Load; Zidovudine

1996
Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments: a meta-analysis of controlled trials.
    AIDS (London, England), 1997, Mar-15, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Disease Progression; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; United States; Zidovudine

1997
Effects of a combination of zidovudine, didanosine, and lamivudine on primary human immunodeficiency virus type 1 infection.
    The Journal of infectious diseases, 1997, Volume: 175, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4-CD8 Ratio; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocytes; Male; Pilot Projects; Proviruses; RNA, Viral; Zidovudine

1997
Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection.
    Science (New York, N.Y.), 1997, May-09, Volume: 276, Issue:5314

    Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Dendritic Cells; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Image Processing, Computer-Assisted; In Situ Hybridization; Kinetics; Lamivudine; Leukocytes, Mononuclear; Macrophages; Palatine Tonsil; Proviruses; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Viral Load; Virus Replication; Zidovudine

1997
Randomised trial of addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens for patients with HIV-1 infection: the CAESAR trial.
    Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063

    Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Health Services; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1997
Cytomegalovirus retinitis after initiation of highly active antiretroviral therapy.
    Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Saquinavir; Zidovudine

1997
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.
    The New England journal of medicine, 1997, Sep-11, Volume: 337, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine

1997
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy.
    The New England journal of medicine, 1997, Sep-11, Volume: 337, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; RNA, Viral; Viral Load; Zidovudine

1997
Stavudine, lamivudine and indinavir in children with advanced HIV-1 infection: preliminary experience.
    AIDS (London, England), 1997, Volume: 11, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pilot Projects; Retrospective Studies; Stavudine; Zidovudine

1997
Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Nov-11, Volume: 94, Issue:23

    Topics: Anti-HIV Agents; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymph Nodes; RNA, Viral; Viral Load; Zidovudine

1997
Quantification of HIV-1 proviral DNA by a standardized colorimetric PCR-based assay.
    Journal of medical virology, 1998, Volume: 54, Issue:1

    Topics: Adult; Anti-HIV Agents; Colorimetry; Didanosine; DNA, Viral; Evaluation Studies as Topic; Female; HIV-1; Humans; Indinavir; Lamivudine; Male; Polymerase Chain Reaction; Proviruses; Ritonavir; RNA, Viral; Transcription, Genetic; Zalcitabine; Zidovudine

1998
Decrease of HIV-1 RNA levels in lymphoid tissue and peripheral blood during treatment with ritonavir, lamivudine and zidovudine. Ritonavir/3TC/ZDV Study Group.
    AIDS (London, England), 1998, Jan-22, Volume: 12, Issue:2

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphoid Tissue; Male; Palatine Tonsil; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

1998
Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy.
    Journal of virology, 1998, Volume: 72, Issue:3

    Topics: Amino Acid Sequence; Base Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Lymph Nodes; Molecular Sequence Data; Mutation; RNA, Viral; Viral Load; Virus Replication; Zidovudine

1998
Antiviral effect of double and triple drug combinations amongst HIV-infected adults: lessons from the implementation of viral load-driven antiretroviral therapy.
    AIDS (London, England), 1998, Feb-12, Volume: 12, Issue:3

    Topics: Adult; Anti-HIV Agents; Cohort Studies; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Multivariate Analysis; Stavudine; Viral Load; Zalcitabine; Zidovudine

1998
The effects of lamivudine treatment on HIV-1 disease progression are highly correlated with plasma HIV-1 RNA and CD4 cell count.
    AIDS (London, England), 1998, Mar-26, Volume: 12, Issue:5

    Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; RNA, Viral; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine

1998
Pilot study of zidovudine-lamivudine combination therapy in vertically HIV-infected antiretroviral-naive children.
    AIDS (London, England), 1998, Mar-26, Volume: 12, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pilot Projects; RNA, Viral; Viral Load; Zidovudine

1998
Impact of zidovudine plus lamivudine or zalcitabine on health-related quality of life.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Quality of Life; Treatment Outcome; Zalcitabine; Zidovudine

1998
A phase I/II study of the protease inhibitor indinavir in children with HIV infection.
    Pediatrics, 1998, Volume: 102, Issue:1 Pt 1

    Topics: Adolescent; Adult; Biological Availability; Capsules; CD4 Lymphocyte Count; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infant; Lamivudine; Male; Suspensions; Viral Load; Virus Replication; Zidovudine

1998
Evolution of cytotoxic T lymphocyte responses to human immunodeficiency virus type 1 in patients with symptomatic primary infection receiving antiretroviral triple therapy.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:1

    Topics: Anti-HIV Agents; Cell Line, Transformed; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; T-Lymphocytes, Cytotoxic; Viral Load; Zidovudine

1998
Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical Trials Group Protocol 315.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:1

    Topics: Adult; Anti-HIV Agents; Antigens; B-Lymphocytes; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Antigens; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hypersensitivity, Delayed; Lamivudine; Lymphocyte Activation; Lymphocyte Count; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; T-Lymphocyte Subsets; Time Factors; Zidovudine

1998
Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up.
    JAMA, 1998, Jul-01, Volume: 280, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Viral Load; Zidovudine

1998
Rate of HIV-1 decline following antiretroviral therapy is related to viral load at baseline and drug regimen.
    AIDS (London, England), 1998, Aug-20, Volume: 12, Issue:12

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Models, Theoretical; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

1998
An open randomized controlled trial of zidovudine plus lamivudine versus stavudine plus lamivudine.
    AIDS (London, England), 1998, Aug-20, Volume: 12, Issue:12

    Topics: Adult; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Homosexuality, Male; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1998
Treatment response and durability of a double protease inhibitor therapy with saquinavir and ritonavir in an observational cohort of HIV-1-infected individuals.
    AIDS (London, England), 1998, Sep-10, Volume: 12, Issue:13

    Topics: Adult; Anti-HIV Agents; CD4-CD8 Ratio; Cohort Studies; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Observation; Risk Factors; Ritonavir; Saquinavir; Treatment Failure; Viral Load; Zidovudine

1998
Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Amniotic Fluid; Anti-HIV Agents; Black People; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Pregnancy; Random Allocation; RNA, Viral; South Africa; Viral Load; Zidovudine

1998
Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-HIV Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Humans; Lamivudine; Male; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Rifabutin; Stavudine; Zidovudine

1998
A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team.
    The Journal of pediatrics, 1998, Volume: 133, Issue:4

    Topics: Adolescent; Anti-HIV Agents; CD4 Antigens; Child; Child, Preschool; Didanosine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Neurodegenerative Diseases; Polymerase Chain Reaction; RNA, Viral; Survival Rate; Zidovudine

1998
Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy. AIDS Clinical Trials Group Study 343 Team.
    The New England journal of medicine, 1998, 10-29, Volume: 339, Issue:18

    Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Multivariate Analysis; Remission Induction; RNA, Viral; Treatment Failure; Viral Load; Zidovudine

1998
A randomized trial of three maintenance regimens given after three months of induction therapy with zidovudine, lamivudine, and indinavir in previously untreated HIV-1-infected patients. Trilège (Agence Nationale de Recherches sur le SIDA 072) Study Team.
    The New England journal of medicine, 1998, Oct-29, Volume: 339, Issue:18

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Remission Induction; RNA, Viral; Treatment Failure; Viral Load; Zidovudine

1998
A randomized double-blind trial of the addition of lamivudine or matching placebo to current nucleoside analogue reverse transcriptase inhibitor therapy in HIV-infected children: the PENTA-4 trial. Paediatric European Network for Treatment of AIDS.
    AIDS (London, England), 1998, Oct-01, Volume: 12, Issue:14

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine

1998
A dose-ranging study to evaluate the safety and efficacy of abacavir alone or in combination with zidovudine and lamivudine in antiretroviral treatment-naive subjects.
    AIDS (London, England), 1998, Nov-12, Volume: 12, Issue:16

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; HIV-1; Humans; Lamivudine; RNA, Viral; Time Factors; Viral Load; Zidovudine

1998
Highly active antiretroviral therapy results in a decrease in CD8+ T cell activation and preferential reconstitution of the peripheral CD4+ T cell population with memory rather than naive cells.
    Antiviral research, 1998, Volume: 39, Issue:3

    Topics: Anti-HIV Agents; Antigens, CD; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Flow Cytometry; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Immunophenotyping; Indinavir; Lamivudine; Lymphocyte Activation; Statistics, Nonparametric; T-Lymphocyte Subsets; Viral Load; Zidovudine

1998
Human immunodeficiency virus type 1 expressing the lamivudine-associated M184V mutation in reverse transcriptase shows increased susceptibility to adefovir and decreased replication capability in vitro.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:1

    Topics: Adenine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Lamivudine; Organophosphonates; Point Mutation; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1999
Randomized, controlled phase II trial of subcutaneous interleukin-2 in combination with highly active antiretroviral therapy (HAART) in HIV patients.
    AIDS (London, England), 1998, Dec-03, Volume: 12, Issue:17

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Injections, Subcutaneous; Interleukin-2; Lamivudine; Male; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; Saquinavir; Viral Load; Zidovudine

1998
Prolonged suppression of human immunodeficiency virus type 1 (HIV-1) viremia in persons with advanced disease results in enhancement of CD4 T cell reactivity to microbial antigens but not to HIV-1 antigens.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antigens, Bacterial; CD4-Positive T-Lymphocytes; Cell Division; Chemokines; Cytokines; Double-Blind Method; Female; HIV Antigens; HIV-1; Humans; Indinavir; Lamivudine; Male; Mitogens; RNA, Viral; Viremia; Zidovudine

1999
The effect of commencing combination antiretroviral therapy soon after human immunodeficiency virus type 1 infection on viral replication and antiviral immune responses.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV-1; Homosexuality, Male; Humans; Lamivudine; Male; Middle Aged; Pilot Projects; Ritonavir; RNA, Viral; T-Lymphocytes, Cytotoxic; Time Factors; Viremia; Virus Replication; Zidovudine

1999
Initial multicenter experience with double nucleoside therapy for human immunodeficiency virus infection during pregnancy.
    Infectious diseases in obstetrics and gynecology, 1998, Volume: 6, Issue:6

    Topics: Adult; Anti-HIV Agents; Canada; Confidence Intervals; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prospective Studies; Statistics, Nonparametric; Treatment Outcome; United States; Zidovudine

1998
[Increased serum level of naive CD8+-T-cells during intensive antiretroviral therapy].
    Nederlands tijdschrift voor geneeskunde, 1998, Oct-03, Volume: 142, Issue:40

    Topics: Antiviral Agents; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Lymphocyte Count; Male; Saquinavir; Zidovudine

1998
Treatment with amprenavir alone or amprenavir with zidovudine and lamivudine in adults with human immunodeficiency virus infection. AIDS Clinical Trials Group 347 Study Team.
    The Journal of infectious diseases, 1999, Volume: 179, Issue:4

    Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Furans; HIV Infections; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Sulfonamides; Zidovudine

1999
Clinical cross-resistance between the HIV-1 protease inhibitors saquinavir and indinavir and correlations with genotypic mutations.
    AIDS (London, England), 1999, Feb-25, Volume: 13, Issue:3

    Topics: CD4 Lymphocyte Count; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Viral Load; Zidovudine

1999
[Experiences with antiretroviral combination therapy].
    Ugeskrift for laeger, 1999, Mar-22, Volume: 161, Issue:12

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; N-Glycosyl Hydrolases; Retrospective Studies; Ritonavir; RNA, Viral; Zidovudine

1999
Cerebrospinal-fluid HIV-1 RNA and drug concentrations after treatment with lamivudine plus zidovudine or stavudine.
    Lancet (London, England), 1998, May-23, Volume: 351, Issue:9115

    Topics: Adult; AIDS Dementia Complex; Analysis of Variance; Anti-HIV Agents; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Drug Combinations; Follow-Up Studies; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; RNA, Viral; Spinal Puncture; Stavudine; Zidovudine

1998
Lamivudine/zidovudine as a combined formulation tablet: bioequivalence compared with lamivudine and zidovudine administered concurrently and the effect of food on absorption.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:6

    Topics: Absorption; Adolescent; Adult; Anti-HIV Agents; Area Under Curve; Cross-Over Studies; Eating; Fasting; Female; Food-Drug Interactions; Headache; Humans; Lamivudine; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Tablets; Therapeutic Equivalency; Zidovudine

1999
Randomized trial comparing saquinavir soft gelatin capsules versus indinavir as part of triple therapy (CHEESE study).
    AIDS (London, England), 1999, May-07, Volume: 13, Issue:7

    Topics: Adult; Anti-HIV Agents; Capsules; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Gelatin; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Treatment Outcome; Zidovudine

1999
Single-dose pharmacokinetics and safety of abacavir (1592U89), zidovudine, and lamivudine administered alone and in combination in adults with human immunodeficiency virus infection.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:7

    Topics: Adolescent; Adult; Anti-HIV Agents; Cross-Over Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Zidovudine

1999
Safety and efficacy of ritonavir and saquinavir in combination with zidovudine and lamivudine.
    Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Genotype; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Mutation; Pilot Projects; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Severity of Illness Index; Time Factors; Viral Load; Zidovudine

1999
Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cohort Studies; DNA, Viral; Drug Therapy, Combination; HIV Antibodies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Prospective Studies; RNA, Viral; T-Lymphocyte Subsets; Viremia; Zidovudine

1999
The ALBI trial: a randomized controlled trial comparing stavudine plus didanosine with zidovudine plus lamivudine and a regimen alternating both combinations in previously untreated patients infected with human immunodeficiency virus.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viremia; Zidovudine

1999
HIV-1 rebound during interruption of highly active antiretroviral therapy has no deleterious effect on reinitiated treatment. Comet Study Group.
    AIDS (London, England), 1999, Apr-16, Volume: 13, Issue:6

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1999
Lamivudine in combination with zidovudine, stavudine, or didanosine in patients with HIV-1 infection. A randomized, double-blind, placebo-controlled trial. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group Protocol 306 Invest
    AIDS (London, England), 1999, Apr-16, Volume: 13, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Viral Load; Zidovudine

1999
HIV infection perturbs DNA content of lymphoid cells: partial correction after 'suppression' of virus replication.
    AIDS (London, England), 1999, Jul-09, Volume: 13, Issue:10

    Topics: Anti-HIV Agents; Apoptosis; Cell Cycle; Cross-Sectional Studies; DNA; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Ritonavir; RNA, Viral; Viral Load; Virus Replication; Zidovudine

1999
A randomized, controlled trial of indinavir, zidovudine, and lamivudine in adults with advanced human immunodeficiency virus type 1 infection and prior antiretroviral therapy.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Survival Rate; Zidovudine

1999
Cerebrospinal fluid human immunodeficiency virus type 1 (HIV-1) suppression and efavirenz drug concentrations in HIV-1-infected patients receiving combination therapy.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Viral Load; Zidovudine

1999
Immune reconstitution after 2 years of successful potent antiretroviral therapy in previously untreated human immunodeficiency virus type 1-infected adults.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Follow-Up Studies; HIV-1; Humans; Immunologic Memory; Lamivudine; Lymphocyte Count; Lymphocytes; Reference Values; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; T-Lymphocytes; Time Factors; Viral Load; Zidovudine

1999
Highly active antiretroviral treatment initiated early in the course of symptomatic primary HIV-1 infection: results of the ANRS 053 trial.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:4

    Topics: Anti-HIV Agents; Confidence Intervals; Drug Therapy, Combination; Female; France; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Male; Ritonavir; RNA, Viral; Viral Load; Zidovudine

1999
Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients.
    AIDS research and human retroviruses, 1999, Sep-01, Volume: 15, Issue:13

    Topics: Adult; Anti-HIV Agents; Cytokines; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hypersensitivity, Delayed; Interleukin-2; Lamivudine; Lymphocyte Activation; Male; T-Lymphocytes; Thalidomide; Viral Load; Zidovudine

1999
Long-term effects of antiretroviral combination therapy on HIV type 1 DNA levels.
    AIDS research and human retroviruses, 1999, Sep-20, Volume: 15, Issue:14

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Data Interpretation, Statistical; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Polymerase Chain Reaction; RNA, Viral; Stavudine; Time Factors; Zidovudine

1999
Cell-associated HIV-1 messenger RNA and DNA in T-helper cell and monocytes in asymptomatic HIV-1-infected subjects on HAART plus an inactivated HIV-1 immunogen.
    AIDS (London, England), 1999, Sep-10, Volume: 13, Issue:13

    Topics: AIDS Vaccines; Anti-HIV Agents; CD4 Lymphocyte Count; Combined Modality Therapy; DNA, Viral; Drug Therapy, Combination; Freund's Adjuvant; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Monocytes; Pilot Projects; RNA, Viral; T-Lymphocytes, Helper-Inducer; Viral Load; Zidovudine

1999
Preliminary experiences with triple therapy including nelfinavir and two reverse transcriptase inhibitors in previously untreated HIV-infected children.
    AIDS (London, England), 1999, Sep-10, Volume: 13, Issue:13

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nelfinavir; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine

1999
Evidence of stavudine-related phenotypic resistance among zidovudine-pretreated HIV-1-infected subjects receiving a therapeutic regimen of stavudine plus lamivudine.
    Journal of acquired immune deficiency syndromes (1999), 1999, Sep-01, Volume: 22, Issue:1

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Phenotype; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Zidovudine

1999
Lamivudine reduces healthcare resource use when added to zidovudine-containing regimens in patients with HIV infection.
    PharmacoEconomics, 1999, Volume: 15 Suppl 1

    Topics: Adult; Ambulatory Care; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Length of Stay; Male; Zidovudine

1999
A prospective cost-consequence analysis of adding lamivudine to zidovudine-containing antiretroviral treatment regimens for HIV infection in the US.
    PharmacoEconomics, 1999, Volume: 15 Suppl 1

    Topics: Adult; Ambulatory Care; Anti-HIV Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Female; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Length of Stay; Male; Middle Aged; Prospective Studies; United States; Zidovudine

1999
A prospective evaluation of the cost effectiveness of adding lamivudine to zidovudine-containing antiretroviral treatment regimens in HIV infection. European perspective.
    PharmacoEconomics, 1999, Volume: 15 Suppl 1

    Topics: Adult; Ambulatory Care; Anti-HIV Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Europe; Female; Health Care Costs; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Male; Prospective Studies; Zidovudine

1999
An evaluation of the cost effectiveness of adding lamivudine to zidovudine-containing regimens in HIV infection. Canadian perspective.
    PharmacoEconomics, 1999, Volume: 15 Suppl 1

    Topics: Adult; Ambulatory Care; Anti-HIV Agents; Canada; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Female; Health Care Costs; Health Resources; HIV Infections; Hospitalization; Humans; Lamivudine; Male; Prospective Studies; Zidovudine

1999
Quality of life and treatment satisfaction after the addition of lamivudine or lamivudine plus loviride to zidovudine-containing regimens in treatment-experienced patients with HIV infection.
    PharmacoEconomics, 1999, Volume: 15 Suppl 1

    Topics: Acetamides; Acetophenones; Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Patient Satisfaction; Quality of Life; Zidovudine

1999
A randomized study comparing triple versus double antiretroviral therapy or no treatment in HIV-1-infected patients in very early stage disease: the Spanish Earth-1 study.
    AIDS (London, England), 1999, Dec-03, Volume: 13, Issue:17

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-CD8 Ratio; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Palatine Tonsil; Ritonavir; RNA, Viral; Spain; Stavudine; Viremia; Zalcitabine; Zidovudine

1999
A phase II safety and efficacy study of amprenavir in combination with zidovudine and lamivudine in HIV-infected patients with limited antiretroviral experience. Amprenavir PROAB2002 Study Team.
    AIDS (London, England), 1999, Dec-03, Volume: 13, Issue:17

    Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Female; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nausea; RNA, Viral; Safety; Sulfonamides; Time Factors; Viremia; Zidovudine

1999
Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team.
    The New England journal of medicine, 1999, Dec-16, Volume: 341, Issue:25

    Topics: Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1999
Alteration of complement protein levels after antiretroviral therapy in HIV-infected persons.
    AIDS research and human retroviruses, 1999, Dec-10, Volume: 15, Issue:18

    Topics: Anti-HIV Agents; Complement Pathway, Classical; Complement System Proteins; Drug Administration Schedule; Drug Therapy, Combination; HIV Antibodies; HIV Antigens; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine

1999
T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART).
    Blood, 2000, Jan-01, Volume: 95, Issue:1

    Topics: Anti-HIV Agents; Antigens, CD; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; HIV Seronegativity; HIV-1; Humans; Indinavir; Ki-67 Antigen; Lamivudine; Longitudinal Studies; Lymphocyte Activation; RNA, Viral; Saquinavir; T-Lymphocyte Subsets; T-Lymphocytes; Viral Load; Zidovudine

2000
Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic response.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:1

    Topics: Anti-HIV Agents; Candida; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; Humans; Hypersensitivity, Delayed; Immune System; Lamivudine; Mumps virus; Ritonavir; RNA, Viral; Zidovudine

2000
Update on study 006--EFV + AZT + 3TC versus the current 'standard of care' IDV + AZT + 3TC.
    International journal of clinical practice. Supplement, 1999, Volume: 103

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Humans; Indinavir; Lamivudine; Lipid Metabolism; Oxazines; Viral Load; Zidovudine

1999
Interruption of reverse transcriptase inhibitors or a switch from reverse transcriptase to protease inhibitors resulted in a fast reappearance of virus strains with a reverse transcriptase inhibitor-sensitive genotype.
    AIDS (London, England), 1999, Dec-24, Volume: 13, Issue:18

    Topics: Amino Acid Substitution; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Zidovudine

1999
Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy. Trilège (Agence Nationale de Recherches sur le SIDA 072) Study Team).
    JAMA, 2000, Jan-12, Volume: 283, Issue:2

    Topics: Anti-HIV Agents; Case-Control Studies; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Patient Compliance; Treatment Failure; Viral Load; Zidovudine

2000
Cerebrospinal fluid beta2-microglobulin, monocyte chemotactic protein-1, and soluble tumour necrosis factor alpha receptors before and after treatment with lamivudine plus zidovudine or stavudine.
    Journal of neuroimmunology, 2000, Jan-24, Volume: 102, Issue:2

    Topics: Adult; Anti-HIV Agents; beta 2-Microglobulin; Chemokine CCL2; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Middle Aged; Receptors, Tumor Necrosis Factor; Solubility; Stavudine; Zidovudine

2000
Nucleoside analogs plus ritonavir in stable antiretroviral therapy-experienced HIV-infected children: a randomized controlled trial. Pediatric AIDS Clinical Trials Group 338 Study Team.
    JAMA, 2000, Jan-26, Volume: 283, Issue:4

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Stavudine; Viral Load; Zidovudine

2000
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine-lamivudine-ritonavir: genotypic analysis of human immunodeficiency virus type 1 isolates from AIDS clinical trials group protocol 315.ACTG Protocol 315 Team.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:2

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Viral Load; Zidovudine

2000
RANTES production by T cells and CD8-mediated inhibition of human immunodeficiency virus gene expression before initiation of potent antiretroviral therapy predict sustained suppression of viral replication.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Chemokine CCL5; Gene Expression; HIV Infections; HIV Long Terminal Repeat; HIV-1; Humans; Lamivudine; Predictive Value of Tests; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Single-Blind Method; T-Lymphocytes; Viral Load; Virus Replication; Zidovudine

2000
Human immunodeficiency virus-infected persons with mutations conferring resistance to zidovudine show reduced virologic responses to hydroxyurea and stavudine-lamivudine.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:2

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Hydroxyurea; Lamivudine; Logistic Models; Mutation; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine

2000
Prediction of HIV-1 RNA suppression and its durability during treatment with zidovudine/lamivudine.
    Antiviral therapy, 1998, Volume: 3, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV-1; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; RNA, Viral; Zidovudine

1998
Zidovudine resensitization and dual HIV-1 resistance to zidovudine and lamivudine in the delta lamivudine roll-over study.
    Antiviral therapy, 1999, Volume: 4, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Resistance; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Phenotype; RNA, Viral; Zidovudine

1999
AVANTI 1: randomized, double-blind trial to evaluate the efficacy and safety of zidovudine plus lamivudine versus zidovudine plus lamivudine plus loviride in HIV-infected antiretroviral-naive patients. AVANTI Study Group.
    Antiviral therapy, 1999, Volume: 4, Issue:2

    Topics: Acetamides; Acetophenones; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Zidovudine

1999
Effects of early antiretroviral treatment on HIV-1 RNA in blood and lymphoid tissue: a randomized trial of double versus triple therapy. Swiss HIV Cohort Study.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jan-01, Volume: 23, Issue:1

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphoid Tissue; Male; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Time Factors; Viral Load; Zidovudine

2000
HIV-1 reverse transcriptase (RT) genotype and susceptibility to RT inhibitors during abacavir monotherapy and combination therapy.
    AIDS (London, England), 2000, Jan-28, Volume: 14, Issue:2

    Topics: Cohort Studies; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2000
Response to immunization with recall and neoantigens after prolonged administration of an HIV-1 protease inhibitor-containing regimen. ACTG 375 team. AIDS Clinical Trials Group.
    AIDS (London, England), 2000, Jan-07, Volume: 14, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination; Female; Hemocyanins; Hepatitis A Vaccines; HIV-1; Humans; Hypersensitivity, Delayed; Injections, Intradermal; Lamivudine; Male; Middle Aged; Ritonavir; T-Lymphocytes; Tetanus Toxoid; Thymus Gland; Vaccination; Viral Hepatitis Vaccines; Zidovudine

2000
AVANTI 2. Randomized, double-blind trial to evaluate the efficacy and safety of zidovudine plus lamivudine versus zidovudine plus lamivudine plus indinavir in HIV-infected antiretroviral-naive patients.
    AIDS (London, England), 2000, Mar-10, Volume: 14, Issue:4

    Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Patient Compliance; Placebos; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2000
The effects of protease inhibitor therapy on human immunodeficiency virus type 1 levels in semen (AIDS clinical trials group protocol 850).
    The Journal of infectious diseases, 2000, Volume: 181, Issue:5

    Topics: Adult; Carbamates; Double-Blind Method; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Regression Analysis; RNA, Viral; Semen; Sulfonamides; Virus Shedding; Zidovudine

2000
Efficacy, safety, and adherence with a twice-daily combination lamivudine/zidovudine tablet formulation, plus a protease inhibitor, in HIV infection.
    AIDS (London, England), 2000, Apr-14, Volume: 14, Issue:6

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Patient Compliance; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2000
A randomized, controlled, phase II trial comparing escalating doses of subcutaneous interleukin-2 plus antiretrovirals versus antiretrovirals alone in human immunodeficiency virus-infected patients with CD4+ cell counts >/=350/mm3.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:5

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Injections, Subcutaneous; Interleukin-2; Lamivudine; Lymphocyte Count; Male; Nelfinavir; Nevirapine; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Zalcitabine; Zidovudine

2000
Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease.
    AIDS (London, England), 2000, May-05, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cytokines; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load; Virus Replication; Zidovudine

2000
Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapy.
    AIDS (London, England), 2000, May-05, Volume: 14, Issue:7

    Topics: Adult; Alleles; Anti-HIV Agents; Chemokine CXCL12; Chemokines, CXC; Drug Therapy, Combination; Female; Gene Frequency; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Linkage Disequilibrium; Male; Polymorphism, Genetic; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, Cytokine; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine

2000
Dual nucleoside regimens in nonadvanced HIV infection: prospective follow-up of 130 patients, Aquitaine Cohort, 1996 to 1998. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine (GECSA).
    Journal of acquired immune deficiency syndromes (1999), 2000, Mar-01, Volume: 23, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Multivariate Analysis; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Zalcitabine; Zidovudine

2000
Clinical and virologic response to combination treatment with indinavir, zidovudine, and lamivudine in children with human immunodeficiency virus-1 infection: a multicenter study in the Netherlands. On behalf of the Dutch Study Group for Children with HIV
    The Journal of pediatrics, 2000, Volume: 136, Issue:6

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Netherlands; Prospective Studies; Zidovudine

2000
Improved prognosis in patients with acquired immunodeficiency syndrome-related lymphoma.
    Cancer biotherapy & radiopharmaceuticals, 1999, Volume: 14, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease-Free Survival; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lymphoma, AIDS-Related; Male; Middle Aged; Mitoxantrone; Prognosis; Survival Rate; Vincristine; Zidovudine

1999
Effect of two different combinations of antiretrovirals (AZT+ddI and AZT+3TC) on cytokine production and apoptosis in asymptomatic HIV infection.
    Antiviral research, 2000, Volume: 46, Issue:3

    Topics: Anti-HIV Agents; Apoptosis; CD4 Lymphocyte Count; CD4-CD8 Ratio; Cytokines; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Prospective Studies; Reverse Transcriptase Inhibitors; Th1 Cells; Viremia; Zidovudine

2000
3-year suppression of HIV viremia with indinavir, zidovudine, and lamivudine.
    Annals of internal medicine, 2000, Jul-04, Volume: 133, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Genotype; HIV; HIV Infections; Humans; Indinavir; Kidney Calculi; Lamivudine; Male; Middle Aged; RNA, Viral; Viral Load; Viremia; Zidovudine

2000
A randomised, open-label comparison of three highly active antiretroviral therapy regimens including two nucleoside analogues and indinavir for previously untreated HIV-1 infection: the OzCombo1 study.
    AIDS (London, England), 2000, Jun-16, Volume: 14, Issue:9

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Stavudine; Viral Load; Zidovudine

2000
Absence of zidovudine resistance in antiretroviral-naive patients following zidovudine/lamivudine/protease inhibitor combination therapy: virological evaluation of the AVANTI 2 and AVANTI 3 studies.
    AIDS (London, England), 2000, Jun-16, Volume: 14, Issue:9

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Microbial; Female; Genotype; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; RNA, Viral; Viral Load; Zidovudine

2000
Recovery of replication-competent virus from CD4 T cell reservoirs and change in coreceptor use in human immunodeficiency virus type 1-infected children responding to highly active antiretroviral therapy.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:3

    Topics: Adolescent; CD4-Positive T-Lymphocytes; Cell Differentiation; Child; Coculture Techniques; Female; HIV Infections; HIV-1; Humans; Immunophenotyping; Infant; Lamivudine; Leukocytes, Mononuclear; Male; Nelfinavir; Prospective Studies; Receptors, CCR5; Receptors, CXCR4; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Virus Replication; Zidovudine

2000
Virological and immunological effects of combination antiretroviral therapy with zidovudine, lamivudine, and indinavir during primary human immunodeficiency virus type 1 infection.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:3

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Core Protein p24; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Patient Compliance; Zidovudine

2000
Positive influence of the Delta32CCR5 allele on response to highly active antiretroviral therapy (HAART) in HIV-1 infected patients.
    European journal of medical research, 2000, Aug-18, Volume: 5, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Alleles; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Resistance, Microbial; Female; HIV-1; Humans; Lamivudine; Male; Receptors, CCR5; Zidovudine

2000
Comparison of a point mutation assay with a line probe assay for the detection of the major mutations in the HIV-1 reverse transcriptase gene associated with reduced susceptibility to nucleoside analogues.
    Journal of virological methods, 2000, Volume: 88, Issue:2

    Topics: Acetamides; Acetophenones; Anti-HIV Agents; Codon; DNA; DNA Mutational Analysis; Drug Resistance, Microbial; Drug Therapy, Combination; Evaluation Studies as Topic; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

2000
Continued lamivudine versus delavirdine in combination with indinavir and zidovudine or stavudine in lamivudine-experienced patients: results of Adult AIDS Clinical Trials Group protocol 370.
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Delavirdine; Female; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Viral Load; Zidovudine

2000
A comparison of stavudine plus lamivudine versus zidovudine plus lamivudine in combination with indinavir in antiretroviral naive individuals with HIV infection: selection of thymidine analog regimen therapy (START I).
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Thymidine; Zidovudine

2000
A comparison of stavudine, didanosine and indinavir with zidovudine, lamivudine and indinavir for the initial treatment of HIV-1 infected individuals: selection of thymidine analog regimen therapy (START II).
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Viral Load; Zidovudine

2000
Comparative studies of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine.
    AIDS (London, England), 2000, Sep-08, Volume: 14, Issue:13

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Administration Schedule; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2000
Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine.
    AIDS research and human retroviruses, 2000, Sep-20, Volume: 16, Issue:14

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zalcitabine; Zidovudine

2000
Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.
    AIDS (London, England), 2000, Sep-29, Volume: 14, Issue:14

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine

2000
Comparison of immunologic restoration and virologic response in plasma, tonsillar tissue, and cerebrospinal fluid in HIV-1-infected patients treated with double versus triple antiretroviral therapy in very early stages: The Spanish EARTH-2 Study. Early An
    Journal of acquired immune deficiency syndromes (1999), 2000, Sep-01, Volume: 25, Issue:1

    Topics: Adult; Blood; CD4 Lymphocyte Count; Cell Count; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Palatine Tonsil; Point Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Stavudine; Time Factors; Viral Load; Zidovudine

2000
HAART tolerability: post-exposure prophylaxis in healthcare workers versus treatment in HIV-infected patients.
    Antiviral therapy, 2000, Volume: 5, Issue:3

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chemoprevention; Female; Health Personnel; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine

2000
Amprenavir in combination with lamivudine and zidovudine versus lamivudine and zidovudine alone in HIV-1-infected antiretroviral-naive adults. Amprenavir PROAB3001 International Study Team.
    Antiviral therapy, 2000, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Furans; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Sulfonamides; Zidovudine

2000
Altered viral fitness of HIV-1 following failure of protease inhibitor-based therapy.
    Journal of acquired immune deficiency syndromes (1999), 2000, Dec-01, Volume: 25, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antigens, Viral; Base Sequence; CD4-Positive T-Lymphocytes; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Mice; Mice, SCID; Molecular Sequence Data; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Sequence Analysis, DNA; Viral Load; Zidovudine

2000
Dose-finding study of once-daily indinavir/ritonavir plus zidovudine and lamivudine in HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2000, Nov-01, Volume: 25, Issue:3

    Topics: Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Pilot Projects; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine

2000
Pharmacological basis for concentration-controlled therapy with zidovudine, lamivudine, and indinavir.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:1

    Topics: Adult; Algorithms; Anti-HIV Agents; Area Under Curve; Drug Therapy, Combination; Female; Half-Life; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Patient Compliance; Zidovudine

2001
A randomized, double-blind study of triple nucleoside therapy of abacavir, lamivudine, and zidovudine versus lamivudine and zidovudine in previously treated human immunodeficiency virus type 1-infected children. The CNAA3006 Study Team.
    Pediatrics, 2001, Volume: 107, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Confidence Intervals; Dideoxynucleosides; Disease Progression; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Growth; HIV-1; Humans; Infant; Lamivudine; Male; RNA, Viral; Zidovudine

2001
Plasma population pharmacokinetics and penetration into cerebrospinal fluid of indinavir in combination with zidovudine and lamivudine in HIV-1-infected patients.
    AIDS (London, England), 2000, Dec-22, Volume: 14, Issue:18

    Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine

2000
Twice-daily triple nucleoside intensification treatment with lamivudine-zidovudine plus abacavir sustains suppression of human immunodeficiency virus type 1: results of the TARGET Study.
    The Journal of infectious diseases, 2001, Feb-15, Volume: 183, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2001
Virologic and CD4 cell response to zidovudine or zidovudine and lamivudine following didanosine treatment of human immunodeficiency virus infection.
    AIDS research and human retroviruses, 2001, Feb-10, Volume: 17, Issue:3

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine

2001
Alterations in T cell phenotype and human immunodeficiency virus type 1-specific cytotoxicity after potent antiretroviral therapy.
    The Journal of infectious diseases, 2001, Mar-01, Volume: 183, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Epitopes, T-Lymphocyte; Flow Cytometry; HIV Infections; HIV-1; HLA-DR Antigens; Humans; Immunodominant Epitopes; Immunohistochemistry; Immunophenotyping; Indinavir; Lamivudine; Leukocyte Common Antigens; Prospective Studies; Protein Tyrosine Phosphatase, Non-Receptor Type 1; T-Lymphocytes, Cytotoxic; Viral Load; Zidovudine

2001
Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial.
    JAMA, 2001, Mar-07, Volume: 285, Issue:9

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Resistance, Microbial; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Indinavir; Lamivudine; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Survival Analysis; Therapeutic Equivalency; Viral Load; Zidovudine

2001
Long-term virologic and immunologic responses in human immunodeficiency virus type 1-infected children treated with indinavir, zidovudine, and lamivudine.
    The Journal of infectious diseases, 2001, Apr-01, Volume: 183, Issue:7

    Topics: Adolescent; Anti-HIV Agents; CD4 Antigens; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Leukocyte Common Antigens; Male; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RNA, Viral; Viral Load; Zidovudine

2001
Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection.
    AIDS (London, England), 2001, Mar-09, Volume: 15, Issue:4

    Topics: Adult; Anti-HIV Agents; Central Nervous System Diseases; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Motor Skills; Stavudine; Zalcitabine; Zidovudine

2001
Abacavir/lamivudine/zidovudine as a combined formulation tablet: bioequivalence compared with each component administered concurrently and the effect of food on absorption.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:3

    Topics: Absorption; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Eating; Fasting; Female; Half-Life; Humans; Lamivudine; Male; Mass Spectrometry; Middle Aged; Reverse Transcriptase Inhibitors; Therapeutic Equivalency; Zidovudine

2001
An open-label randomized trial to evaluate different therapeutic strategies of combination therapy in HIV-1 infection: design, rationale, and methods of the initio trial.
    Controlled clinical trials, 2001, Volume: 22, Issue:2

    Topics: Adult; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Selection; Randomized Controlled Trials as Topic; Research Design; Ritonavir; Sample Size; Saquinavir; Stavudine; Zidovudine

2001
A comparison of the steady-state pharmacokinetics and safety of abacavir, lamivudine, and zidovudine taken as a triple combination tablet and as abacavir plus a lamivudine-zidovudine double combination tablet by HIV-1-infected adults.
    Pharmacotherapy, 2001, Volume: 21, Issue:4

    Topics: Adult; Area Under Curve; Cross-Over Studies; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Half-Life; HIV Infections; HIV-1; Humans; Lamivudine; Male; Metabolic Clearance Rate; Reverse Transcriptase Inhibitors; Tablets; Zidovudine

2001
Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1.
    JAMA, 2001, Apr-25, Volume: 285, Issue:16

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Multivariate Analysis; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine

2001
Challenges of antiretroviral treatment in transient and drug-using populations: the SUN study.
    AIDS patient care and STDs, 2001, Volume: 15, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; Capsules; CD4 Lymphocyte Count; Chemistry, Pharmaceutical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Mental Disorders; Patient Compliance; Pilot Projects; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Saquinavir; Substance Abuse, Intravenous; Transients and Migrants; Treatment Outcome; Viral Load; Zidovudine

2001
Open-label phase II trial of amprenavir, abacavir, and fixed-dose zidovudine/lamivudine in newly and chronically HIV-1--infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2001, Apr-01, Volume: 26, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Chronic Disease; Dideoxynucleosides; Digestive System; Drug Synergism; Ethnicity; Female; Furans; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Subsets; Male; Pregnancy; Research Design; RNA, Viral; Sulfonamides; Treatment Refusal; Zidovudine

2001
Loss of antiviral effect owing to zidovudine and lamivudine double resistance in HIV-1-infected patients in an ongoing open-label trial.
    Antiviral therapy, 1997, Volume: 2, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV-1; Humans; Lamivudine; Mutation; Phenotype; RNA, Viral; Zidovudine

1997
Combination shows reduction in viral levels.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; HIV Seropositivity; Humans; Indinavir; Lamivudine; Time Factors; Zidovudine

1996
Drug combination shows benefits for AIDS patients with history of taking AZT.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; HIV; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Zidovudine

1996
Phase II/III Trials of Viracept start.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:3

    Topics: Anti-HIV Agents; Blood; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Pilot Projects; Reverse Transcriptase Inhibitors; Stavudine; Sulfonic Acids; Time Factors; Zidovudine

1996
Research study of combination AIDS therapies underway.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:1

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Nevirapine; Pyridines; Zidovudine

1996
Final CESARE trial results show continued clinical and survival benefit.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:2

    Topics: Acetamides; Acetophenones; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Survival Rate; Zalcitabine; Zidovudine

1997
Preliminary data on 141W94 reported.
    AIDS patient care and STDs, 1998, Volume: 12, Issue:1

    Topics: Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sulfonamides; Zidovudine

1998
Phase III results presented on amprenavir triple combination.
    AIDS patient care and STDs, 1998, Volume: 12, Issue:12

    Topics: Anti-HIV Agents; Carbamates; Drug Administration Schedule; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sulfonamides; Zidovudine

1998
Merck protease inhibitor trial seeks persons with CD4 count under 50.
    AIDS treatment news, 1995, Jun-16, Issue:no 225

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Industry; Drug Therapy, Combination; HIV Protease Inhibitors; Hotlines; Humans; Indinavir; Lamivudine; Patient Selection; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1995
New protease inhibitor studies.
    Treatment review, 1995, Issue:no 18

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Randomized Controlled Trials as Topic; Zalcitabine; Zidovudine

1995
Treatment for primary infection.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:12

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Cohort Studies; Controlled Clinical Trials as Topic; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Placebos; Pyridines; Ritonavir; Thiazoles; Valine; Zalcitabine; Zidovudine

1995
New double vs. triple antiviral combination study, CD4 200-500, no prior treatment.
    AIDS treatment news, 1995, Dec-01, Issue:no 236

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1995
Agouron starts phase III protease inhibitor studies.
    AIDS treatment news, 1996, Feb-09, Issue:no 240

    Topics: Adolescent; Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Placebos; Zalcitabine; Zidovudine

1996
Antiretroviral combination treatment prolongs life in people with HIV/AIDS.
    AmFAR report, 1996

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
Protease inhibitors: major study stopped when 3-drug arm proves superior.
    AIDS treatment news, 1997, Mar-07, Issue:No 266

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Treatment Outcome; Zidovudine

1997
Major pediatric study stopped early: combination treatment better.
    AIDS treatment news, 1997, Jul-04, Issue:No 274

    Topics: Anti-HIV Agents; Child; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine

1997
Combination therapies improve outlook for children with HIV disease.
    NIAID AIDS agenda, 1997

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Infant; Lamivudine; Zidovudine

1997
Delavirdine combination and viral load.
    AIDS treatment news, 1997, Oct-17, Issue:No 281

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Delavirdine; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1997
Lactic acid levels in children perinatally treated with antiretroviral agents to prevent HIV transmission.
    AIDS (London, England), 2001, May-25, Volume: 15, Issue:8

    Topics: Anti-HIV Agents; Cross-Sectional Studies; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lactic Acid; Lamivudine; Male; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2001
Low incidence of genotypic and phenotypic resistance in paediatric HIV-infected patients on long-term first-line antiretroviral triple therapy.
    AIDS (London, England), 2001, May-25, Volume: 15, Issue:8

    Topics: Adolescent; Child; Child, Preschool; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Ritonavir; Time; Viral Load; Zidovudine

2001
A randomized, open-label, comparative trial of zidovudine plus lamivudine versus zidovudine plus lamivudine plus didanosine in antiretroviral-naive HIV-1-infected Thai patients.
    Journal of acquired immune deficiency syndromes (1999), 2001, Jun-01, Volume: 27, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Thailand; Treatment Outcome; Zidovudine

2001
Durable HIV-1 suppression with indinavir after failing lamivudine-containing double nucleoside therapy: a randomized controlled trial.
    Antiviral therapy, 2001, Volume: 6, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; Follow-Up Studies; HIV-1; Humans; Indinavir; Lamivudine; Middle Aged; Prospective Studies; RNA, Viral; Zidovudine

2001
Long-term protease inhibitor-containing therapy results in limited improvement in T cell function but not restoration of interleukin-12 production in pediatric patients with AIDS.
    The Journal of infectious diseases, 2001, Jul-15, Volume: 184, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Antigens; HIV Protease Inhibitors; Humans; Indinavir; Interleukin-12; Lamivudine; Male; Phytohemagglutinins; T-Lymphocytes; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2001
Pharmacokinetics of zidovudine and lamivudine in neonates following coadministration of oral doses every 12 hours.
    Journal of clinical pharmacology, 2001, Volume: 41, Issue:7

    Topics: Adult; Area Under Curve; Breast Feeding; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Female; Half-Life; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Metabolic Clearance Rate; Pregnancy; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2001
AVANTI 3: a randomized, double-blind trial to compare the efficacy and safety of lamivudine plus zidovudine versus lamivudine plus zidovudine plus nelfinavir in HIV-1-infected antiretroviral-naive patients.
    Antiviral therapy, 2001, Volume: 6, Issue:2

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Clinical Protocols; Diarrhea; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nausea; Nelfinavir; Patient Compliance; RNA, Viral; Zidovudine

2001
Treatment intensification with abacavir in HIV-infected patients with at least 12 weeks previous lamivudine/zidovudine treatment.
    Antiviral therapy, 2001, Volume: 6, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Time Factors; Zidovudine

2001
Effects of treatment intensification with hydroxyurea in HIV-infected patients with virologic suppression.
    AIDS (London, England), 2001, Jul-27, Volume: 15, Issue:11

    Topics: Adolescent; Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; Drug Therapy, Combination; Enzyme Inhibitors; Female; HIV Infections; Humans; Hydroxyurea; Indinavir; Lamivudine; Male; Nucleic Acid Synthesis Inhibitors; Pancreatitis; Prospective Studies; Survival Analysis; Treatment Failure; Viral Load; Zidovudine

2001
Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine.
    The Journal of infectious diseases, 2001, Sep-15, Volume: 184, Issue:6

    Topics: Adult; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Phenotype; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2001
The effect of antiretroviral therapy on HTLV infection.
    Virus research, 2001, Oct-30, Volume: 78, Issue:1-2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deltaretrovirus Infections; DNA, Viral; Drug Therapy, Combination; Female; HIV-1; Human T-lymphotropic virus 1; Human T-lymphotropic virus 2; Humans; Lamivudine; Male; Middle Aged; Proviruses; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2001
Triple nuke therapy--results after one year.
    TreatmentUpdate, 2001,Winter, Volume: 12, Issue:10

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2001
Potential adverse effects of structured therapeutic interruptions on the pool of HIV-infected cells.
    Journal of acquired immune deficiency syndromes (1999), 2001, Oct-01, Volume: 28, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Disease Progression; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Morbidity; Prognosis; Ritonavir; RNA, Viral; Saquinavir; Viral Load; Zidovudine

2001
Randomized, double-blind comparison of two nelfinavir doses plus nucleosides in HIV-infected patients (Agouron study 511).
    AIDS (London, England), 2001, Oct-19, Volume: 15, Issue:15

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine

2001
Predictors of virologic and clinical outcomes in HIV-1-infected patients receiving concurrent treatment with indinavir, zidovudine, and lamivudine. AIDS Clinical Trials Group Protocol 320.
    Annals of internal medicine, 2001, Dec-04, Volume: 135, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Protocols; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Logistic Models; Male; Middle Aged; RNA, Viral; Viral Load; Zidovudine

2001
Failure of stavudine-lamivudine combination therapy in antiretroviral-naive patients with AZT-like HIV-1 resistance mutations.
    Journal of medical virology, 2001, Volume: 65, Issue:4

    Topics: Anti-HIV Agents; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Mutation; Stavudine; Treatment Failure; Zidovudine

2001
Response to lamivudine-zidovudine plus abacavir twice daily in antiretroviral-naive, incarcerated patients with HIV infection taking directly observed treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Feb-15, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Therapy, Combination; Female; Health Care Costs; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Treatment Outcome; Zidovudine

2002
Evidence of immune reconstitution in antiretroviral drug-experienced patients with advanced HIV disease.
    AIDS research and human retroviruses, 2002, Jan-20, Volume: 18, Issue:2

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cyclopropanes; Didanosine; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2002
Concentration-controlled compared with conventional antiretroviral therapy for HIV infection.
    AIDS (London, England), 2002, Mar-08, Volume: 16, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Feasibility Studies; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

2002
Final analysis of the Trilège induction-maintenance trial: results at 18 months.
    AIDS (London, England), 2002, Mar-08, Volume: 16, Issue:4

    Topics: Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Multivariate Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2002
Results of 2 years of treatment with protease-inhibitor--containing antiretroviral therapy in dutch children infected with human immunodeficiency virus type 1.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Apr-01, Volume: 34, Issue:7

    Topics: Adolescent; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Netherlands; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine

2002
Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial.
    Lancet (London, England), 2002, Mar-02, Volume: 359, Issue:9308

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2002
[A clinical trial using zidovudine and lamivudine plus indinavir triple therapy in Chinese individuals with human immunodeficiency virus infection].
    Zhonghua nei ke za zhi, 2002, Volume: 41, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; China; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Count; Male; Middle Aged; RNA, Viral; Time Factors; Treatment Outcome; Viremia; Zidovudine

2002
Efficacy of three short-course regimens of zidovudine and lamivudine in preventing early and late transmission of HIV-1 from mother to child in Tanzania, South Africa, and Uganda (Petra study): a randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2002, Apr-06, Volume: 359, Issue:9313

    Topics: Adult; Anti-HIV Agents; Breast Feeding; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Multicenter Studies as Topic; Pregnancy; Risk Factors; South Africa; Tanzania; Treatment Outcome; Uganda; Zidovudine

2002
Therapeutic vaccination in primary HIV infection, the Quest trial.
    Vaccine, 2002, May-06, Volume: 20, Issue:15

    Topics: AIDS Vaccines; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Carbamates; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Defective Viruses; Dideoxynucleosides; Furans; HIV Infections; Humans; Immunotherapy, Active; Lamivudine; Lymphocyte Count; Sulfonamides; T-Lymphocyte Subsets; Vaccination; Vaccinia virus; Viral Load; Viral Vaccines; Viremia; Zidovudine

2002
A randomized trial of simplified maintenance therapy with abacavir, lamivudine, and zidovudine in human immunodeficiency virus infection.
    The Journal of infectious diseases, 2002, May-01, Volume: 185, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV-1; Humans; Lamivudine; Lipids; Male; Prospective Studies; RNA, Viral; Treatment Failure; Viral Load; Zidovudine

2002
Observations of HIV-1 genotypic drug resistance in a trial of four reverse transcriptase inhibitors (Quattro Trial).
    Antiviral therapy, 2002, Volume: 7, Issue:1

    Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Viral Load; Zalcitabine; Zidovudine

2002
Mutations in HIV-1 reverse transcriptase during therapy with abacavir, lamivudine and zidovudine in HIV-1-infected adults with no prior antiretroviral therapy.
    Antiviral therapy, 2002, Volume: 7, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Zidovudine

2002
Efficacy of zidovudine compared to stavudine, both in combination with lamivudine and indinavir, in human immunodeficiency virus-infected nucleoside-experienced patients with no prior exposure to lamivudine, stavudine, or protease inhibitors (novavir tria
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:6

    Topics: Adult; Anti-HIV Agents; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2002
Effect of combination antiretroviral therapy on cerebrospinal fluid HIV RNA, HIV resistance, and clinical manifestations of encephalopathy.
    The Journal of pediatrics, 2002, Volume: 141, Issue:1

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Child; Child, Preschool; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; HIV-1; Humans; Infant; Lamivudine; RNA, Viral; Statistics, Nonparametric; Viral Load; Zidovudine

2002
Anti-HIV agents. Indinavir--3 years and still going strong.
    TreatmentUpdate, 2000, Volume: 12, Issue:6

    Topics: Adipose Tissue; Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Viral Load; Zidovudine

2000
The pharmacokinetics of amprenavir, zidovudine, and lamivudine in the genital tracts of men infected with human immunodeficiency virus type 1 (AIDS clinical trials group study 850).
    The Journal of infectious diseases, 2002, Jul-15, Volume: 186, Issue:2

    Topics: Adult; Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; Genitalia, Male; HIV Infections; HIV-1; Humans; Lamivudine; Male; RNA, Viral; Semen; Statistics, Nonparametric; Sulfonamides; Zidovudine

2002
Safety and efficacy of saquinavir soft-gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission.
    Journal of acquired immune deficiency syndromes (1999), 2002, Aug-01, Volume: 30, Issue:4

    Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Safety; Saquinavir; Thailand; United Kingdom; Viremia; Zidovudine

2002
A phase II randomized study of the virologic and immunologic effect of zidovudine + stavudine versus stavudine alone and zidovudine + lamivudine in patients with >300 CD4 cells who were antiretroviral naive (ACTG 298).
    AIDS research and human retroviruses, 2002, Jul-01, Volume: 18, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Stavudine; Zidovudine

2002
A randomized, open-label, comparative trial of BID and TID dosing of saquinavir enhanced oral formulation as part of a triple therapy for advanced AIDS patients.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, Volume: 85, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Female; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Zidovudine

2002
Adherence to antiretroviral therapy and outcomes in HIV-infected patients enrolled in an induction/maintenance randomized trial.
    Antiviral therapy, 2002, Volume: 7, Issue:2

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Patient Compliance; RNA, Viral; Treatment Outcome; Zidovudine

2002
A randomized clinical trial comparing nelfinavir or nevirapine associated to zidovudine/lamivudine in HIV-infected naive patients (the Combine Study).
    Antiviral therapy, 2002, Volume: 7, Issue:2

    Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Argentina; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Nevirapine; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Treatment Outcome; Zidovudine

2002
The efficacy of combined zidovudine and lamivudine compared with that of combined zidovudine, lamivudine and nelfinavir in asymptomatic and early symptomatic HIV-infected children.
    The Southeast Asian journal of tropical medicine and public health, 2002, Volume: 33, Issue:2

    Topics: CD4 Lymphocyte Count; Child, Preschool; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Thailand; Treatment Outcome; Viral Load; Zidovudine

2002
Efficacy and safety of a quadruple combination Combivir + abacavir + efavirenz regimen in antiretroviral treatment-naive HIV-1-infected adults: La Francilienne.
    Journal of acquired immune deficiency syndromes (1999), 2002, Oct-01, Volume: 31, Issue:2

    Topics: Administration, Oral; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; France; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2002
Short-course therapy with zidovudine plus lamivudine for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Thailand.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Dec-01, Volume: 35, Issue:11

    Topics: Adolescent; Adult; Anti-HIV Agents; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Prospective Studies; Thailand; Zidovudine

2002
Time-dependent changes in HIV nucleoside analogue phosphorylation and the effect of hydroxyurea.
    AIDS (London, England), 2002, Dec-06, Volume: 16, Issue:18

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Interactions; Drug Resistance, Viral; Female; HIV Infections; Humans; Hydroxyurea; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Nevirapine; Nucleosides; Phosphorylation; Reverse Transcriptase Inhibitors; Zidovudine

2002
Increased risk of lipoatrophy under stavudine in HIV-1-infected patients: results of a substudy from a comparative trial.
    AIDS (London, England), 2002, Dec-06, Volume: 16, Issue:18

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Constitution; Body Mass Index; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Indinavir; Lamivudine; Male; Middle Aged; Risk Factors; Stavudine; Zidovudine

2002
Effect of zidovudine resistance mutations on virologic response to treatment with zidovudine or stavudine, each in combination with lamivudine and indinavir.
    Journal of acquired immune deficiency syndromes (1999), 2002, Dec-15, Volume: 31, Issue:5

    Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mutation; Patient Compliance; RNA, Viral; Stavudine; Viral Load; Zidovudine

2002
Evolution of antiretroviral phenotypic and genotypic drug resistance in antiretroviral-naive HIV-1-infected children treated with abacavir/lamivudine, zidovudine/lamivudine or abacavir/zidovudine, with or without nelfinavir (the PENTA 5 trial).
    Antiviral therapy, 2002, Volume: 7, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Child; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV-1; Humans; Lamivudine; Nelfinavir; Phenotype; RNA, Viral; Zidovudine

2002
A multicenter randomized controlled trial of nevirapine versus a combination of zidovudine and lamivudine to reduce intrapartum and early postpartum mother-to-child transmission of human immunodeficiency virus type 1.
    The Journal of infectious diseases, 2003, Mar-01, Volume: 187, Issue:5

    Topics: Adult; Anti-HIV Agents; Delivery, Obstetric; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Labor, Obstetric; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine

2003
Genotype and phenotype at baseline and at failure in human immunodeficiency virus-infected antiretroviral-naive patients in a randomized trial comparing zidovudine and lamivudine plus nelfinavir or nevirapine.
    The Journal of infectious diseases, 2003, Feb-15, Volume: 187, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Argentina; Cohort Studies; Drug Therapy, Combination; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Middle Aged; Mutation; Nelfinavir; Nevirapine; Phenotype; Reverse Transcriptase Inhibitors; Spain; Treatment Failure; Zidovudine

2003
Greater reversal of CD4+ cell abnormalities and viral load reduction after initiation of antiretroviral therapy with zidovudine, lamivudine, and nelfinavir before complete HIV type 1 seroconversion.
    AIDS research and human retroviruses, 2003, Volume: 19, Issue:3

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Prospective Studies; RNA, Viral; Viral Load; Zidovudine

2003
TRIZAL study: switching from successful HAART to Trizivir (abacavir-lamivudine-zidovudine combination tablet): 48 weeks efficacy, safety and adherence results.
    HIV medicine, 2003, Volume: 4, Issue:2

    Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Antiviral Agents; Chi-Square Distribution; Cholesterol; Dideoxynucleosides; Drug Combinations; Drug Hypersensitivity; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Protease Inhibitors; RNA, Viral; Statistics, Nonparametric; Triglycerides; Viral Load; Zidovudine

2003
Triple nucleoside combination zidovudine/lamivudine/abacavir versus zidovudine/lamivudine/nelfinavir as first-line therapy in HIV-1-infected adults: a randomized trial.
    Antiviral therapy, 2003, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Zidovudine

2003
Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2003, May-01, Volume: 33, Issue:1

    Topics: Adult; Body Composition; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Stavudine; Zidovudine

2003
Comparison of metabolic abnormalities 48 weeks after switching from highly active antiretroviral therapy containing a non-nucleoside reverse transcriptase inhibitor to Trizivir versus continued highly active antiretroviral therapy.
    AIDS (London, England), 2003, Aug-15, Volume: 17, Issue:12

    Topics: Antiretroviral Therapy, Highly Active; Cholesterol; Dideoxynucleosides; Drug Combinations; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine

2003
Feeding risk cut for HIV-infected women.
    Lancet (London, England), 2003, Jul-26, Volume: 362, Issue:9380

    Topics: Anti-HIV Agents; Breast Feeding; Didanosine; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Rwanda; Uganda; Zidovudine

2003
Nucleoside analogue mutations and Q151M in HIV-1 subtype A/E infection treated with nucleoside reverse transcriptase inhibitors.
    AIDS (London, England), 2003, Sep-05, Volume: 17, Issue:13

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Multiple; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2003
Antiviral dynamics and sex differences of zidovudine and lamivudine triphosphate concentrations in HIV-infected individuals.
    AIDS (London, England), 2003, Oct-17, Volume: 17, Issue:15

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Female; Half-Life; HIV Infections; Humans; Immunoassay; Lamivudine; Male; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Severity of Illness Index; Sex Factors; Zidovudine

2003
Long-term efficacy, safety, and tolerability of indinavir-based therapy in protease inhibitor-naive adults with advanced HIV infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Oct-15, Volume: 37, Issue:8

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; RNA, Viral; Zidovudine

2003
Impact of an educational program on efficacy and adherence with a twice-daily lamivudine/zidovudine/abacavir regimen in underrepresented HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2003, Oct-01, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Patient Compliance; Patient Education as Topic; RNA, Viral; Zidovudine

2003
Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine.
    AIDS (London, England), 2003, Nov-07, Volume: 17, Issue:16

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2003
Field evaluation of an improved assay using a heat-dissociated p24 antigen for adults mainly infected with HIV-1 CRF02_AG strains in Côte d'Ivoire, West Africa.
    Journal of acquired immune deficiency syndromes (1999), 2003, Nov-01, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Cote d'Ivoire; Drug Combinations; Enzyme-Linked Immunosorbent Assay; HIV Antibodies; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Middle Aged; Prospective Studies; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Sensitivity and Specificity; Zidovudine

2003
MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study.
    Journal of acquired immune deficiency syndromes (1999), 2003, Nov-01, Volume: 34, Issue:3

    Topics: Adult; Alleles; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; Female; Genes, MDR; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Ritonavir; RNA, Viral; Zidovudine

2003
Twice-daily Trizivir versus Combivir-abacavir in antiretroviral-experienced adults with human immunodeficiency virus-1 infection: a formulation-switch trial.
    Pharmacotherapy, 2003, Volume: 23, Issue:11

    Topics: Adolescent; Adult; Analysis of Variance; Anti-HIV Agents; Chemistry, Pharmaceutical; Confidence Intervals; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Zidovudine

2003
A pilot study to evaluate the safety and feasibility of the administration of AZT/3TC fixed dose combination to HIV infected pregnant women and their infants in Rio de Janeiro, Brazil.
    Sexually transmitted infections, 2003, Volume: 79, Issue:6

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Brazil; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine

2003
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection.
    The New England journal of medicine, 2003, Dec-11, Volume: 349, Issue:24

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Oxazines; RNA, Viral; Stavudine; Time Factors; Treatment Failure; Zidovudine

2003
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection.
    The New England journal of medicine, 2003, Dec-11, Volume: 349, Issue:24

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nelfinavir; Oxazines; Stavudine; Time Factors; Treatment Failure; Zidovudine

2003
Meeting notes from the 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment. Trizivir vs. efavirenz: results from ACTG 5095.
    AIDS clinical care, 2003, Volume: 15, Issue:9

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Oxazines; Placebos; Viral Load; Zidovudine

2003
TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen.
    AIDS (London, England), 2003, Dec-05, Volume: 17, Issue:18

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine

2003
Detection of drug-resistant minority variants of HIV-1 during virologic failure of indinavir, lamivudine, and zidovudine.
    The Journal of infectious diseases, 2004, Mar-15, Volume: 189, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Resistance, Viral; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Mutation; RNA, Viral; Zidovudine

2004
Elective cesarean delivery plus short-course lamivudine and zidovudine for the prevention of mother-to-child transmission of human immunodeficiency virus type 1.
    American journal of obstetrics and gynecology, 2004, Volume: 190, Issue:3

    Topics: Adult; Anti-HIV Agents; Cesarean Section; Female; HIV Infections; HIV-1; Humans; Incidence; Infant, Newborn; Infant, Newborn, Diseases; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Viral Load; Zidovudine

2004
Rate of thymidine analogue resistance mutation accumulation with zidovudine- or stavudine-based regimens.
    Journal of acquired immune deficiency syndromes (1999), 2004, May-01, Volume: 36, Issue:1

    Topics: Drug Resistance, Multiple, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2004
Pharmacokinetic characteristics of ritonavir, zidovudine, lamivudine, and stavudine in children with human immunodeficiency virus infection.
    Pharmacotherapy, 2004, Volume: 24, Issue:4

    Topics: Adolescent; Anti-HIV Agents; Area Under Curve; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; HIV Infections; Humans; Lamivudine; Male; Metabolic Clearance Rate; Ritonavir; Stavudine; Zidovudine

2004
Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection.
    The New England journal of medicine, 2004, Apr-29, Volume: 350, Issue:18

    Topics: Adult; Aged; Alkynes; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

2004
Immune restoration in HIV-positive, antiretroviral-naive patients after 1 year of zidovudine/lamivudine plus nelfinavir or nevirapine.
    Antiviral therapy, 2004, Volume: 9, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Lamivudine; Lymphocyte Activation; Male; Middle Aged; Nelfinavir; Nevirapine; Reverse Transcriptase Inhibitors; T-Lymphocyte Subsets; Zidovudine

2004
A rapid and sensitive method for simultaneous determination of lamivudine and zidovudine in human serum by on-line solid-phase extraction coupled to liquid chromatography/tandem mass spectrometry detection.
    Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:10

    Topics: Adult; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Therapeutic Equivalency; Zidovudine

2004
Three-year durability of dual-nucleoside versus triple-nucleoside therapy in a Thai population with HIV infection.
    Journal of acquired immune deficiency syndromes (1999), 2004, Jun-01, Volume: 36, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Didanosine; Dideoxynucleosides; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; RNA, Viral; Stavudine; Thailand; Time Factors; Zidovudine

2004
Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose zidovudine and lamivudine, as initial therapy for patients infected with HIV.
    Journal of acquired immune deficiency syndromes (1999), 2004, Aug-15, Volume: 36, Issue:5

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Double-Blind Method; Drug Administration Schedule; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Oligopeptides; Oxazines; Pyridines; RNA, Viral; Zidovudine

2004
Triple nucleoside treatment with abacavir plus the lamivudine/zidovudine combination tablet (COM) compared to indinavir/COM in antiretroviral therapy-naïve adults: results of a 48-week open-label, equivalence trial (CNA3014).
    Current medical research and opinion, 2004, Volume: 20, Issue:7

    Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Patient Compliance; Reverse Transcriptase Inhibitors; RNA; Surveys and Questionnaires; Therapeutic Equivalency; Treatment Outcome; Zidovudine

2004
Predictors of adherence and virologic outcome in HIV-infected patients treated with abacavir- or indinavir-based triple combination HAART also containing lamivudine/zidovudine.
    Current medical research and opinion, 2004, Volume: 20, Issue:7

    Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Patient Compliance; Reverse Transcriptase Inhibitors; Risk Factors; Treatment Outcome; Zidovudine

2004
Once-daily versus twice-daily lamivudine, in combination with zidovudine and efavirenz, for the treatment of antiretroviral-naive adults with HIV infection: a randomized equivalence trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Aug-01, Volume: 39, Issue:3

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2004
Impact of indinavir on the quality of life in patients with advanced HIV infection treated with zidovudine and lamivudine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Aug-01, Volume: 39, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Quality of Life; Reverse Transcriptase Inhibitors; Sickness Impact Profile; Survival Analysis; Zidovudine

2004
HIV-1 drug resistance in subjects with advanced HIV-1 infection in whom antiretroviral combination therapy is failing: a substudy of AIDS Clinical Trials Group Protocol 388.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Aug-15, Volume: 39, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Phenotype; Stavudine; Treatment Failure; Zidovudine

2004
Abacavir versus zidovudine combined with lamivudine and efavirenz, for the treatment of antiretroviral-naive HIV-infected adults.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Oct-01, Volume: 39, Issue:7

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Oxazines; RNA, Viral; Zidovudine

2004
New once-daily HIV combination better tolerated.
    Expert review of anti-infective therapy, 2004, Volume: 2, Issue:6

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Oxazines; Tenofovir; Zidovudine

2004
Persistent antiretroviral activity of nucleoside analogues after prolonged zidovudine and lamivudine therapy as demonstrated by rapid loss of activity after discontinuation.
    Journal of acquired immune deficiency syndromes (1999), 2004, Dec-15, Volume: 37, Issue:5

    Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Zidovudine

2004
A randomized study comparing a three- and four-drug HAART regimen in first-line therapy (QUAD study).
    The Journal of antimicrobial chemotherapy, 2005, Volume: 55, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Lamivudine; Oxazines; Viral Load; Zidovudine

2005
Tolerability of postexposure prophylaxis with the combination of zidovudine-lamivudine and lopinavir-ritonavir for HIV infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Jan-15, Volume: 40, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; Viral Load; Zidovudine

2005
Tenofovir regimen compared with Combivir.
    AIDS patient care and STDs, 2005, Volume: 19, Issue:1

    Topics: Adenine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Europe; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Maximum Tolerated Dose; Organophosphonates; Risk Assessment; Severity of Illness Index; Single-Blind Method; Tenofovir; Treatment Outcome; United States; Viral Load; Zidovudine

2005
Efficacy of tenofovir as intensification of zidovudine/lamivudine/abacavir fixed-dose combination in the treatment of HIV-positive patients.
    Journal of acquired immune deficiency syndromes (1999), 2005, Apr-15, Volume: 38, Issue:5

    Topics: CD4 Lymphocyte Count; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; RNA, Viral; Viral Load; Zidovudine

2005
Field assessment of generic antiretroviral drugs: a prospective cohort study in Cameroon.
    Antiviral therapy, 2005, Volume: 10, Issue:2

    Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Drugs, Generic; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2005
Spontaneous recovery of hemoglobin and neutrophil levels in Japanese patients on a long-term Combivir containing regimen.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2005, Volume: 33, Issue:3

    Topics: Adult; Aged; Anti-HIV Agents; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; HIV Infections; Humans; Japan; Lamivudine; Leukocyte Count; Male; Middle Aged; Neutrophils; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome; Zidovudine

2005
Induction with abacavir/lamivudine/zidovudine plus efavirenz for 48 weeks followed by 48-week maintenance with abacavir/lamivudine/zidovudine alone in antiretroviral-naive HIV-1-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2005, Jul-01, Volume: 39, Issue:3

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Patient Compliance; RNA, Viral; Zidovudine

2005
Antiretroviral treatment simplification with 3 NRTIs or 2 NRTIs plus nevirapine in HIV-1-infected patients treated with successful first-line HAART.
    Journal of acquired immune deficiency syndromes (1999), 2005, Jul-01, Volume: 39, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Patient Compliance; Patient Satisfaction; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

2005
Results of the ALBI trial: a randomized comparison of stavudine/didanosine, zidovudine/lamivudine and alternating treatment in antiretroviral-naive patients.
    Antiviral therapy, 1999, Volume: 4 Suppl 3

    Topics: Anti-HIV Agents; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1999
Effects on immunological and virological outcome of patients using one protease inhibitor or one non-nucleoside reverse transcriptase inhibitor in a triple antiretroviral therapy: normal clinical practice versus clinical trial findings.
    Current HIV research, 2005, Volume: 3, Issue:3

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Oxazines; Retrospective Studies; Treatment Outcome; Tunisia; Viremia; Zidovudine

2005
Antiretroviral concentrations in breast-feeding infants of women in Botswana receiving antiretroviral treatment.
    The Journal of infectious diseases, 2005, Sep-01, Volume: 192, Issue:5

    Topics: Adult; Anti-HIV Agents; Botswana; Breast Feeding; Female; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lactation; Lamivudine; Milk, Human; Nevirapine; Reverse Transcriptase Inhibitors; Statistics, Nonparametric; Zidovudine

2005
Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of age.
    The Pediatric infectious disease journal, 2005, Volume: 24, Issue:9

    Topics: Age Factors; Antiretroviral Therapy, Highly Active; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Lamivudine; Male; Maximum Tolerated Dose; Prospective Studies; Risk Assessment; Ritonavir; Severity of Illness Index; Single-Blind Method; Survival Rate; Treatment Outcome; Zidovudine

2005
Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:10

    Topics: Adult; Area Under Curve; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribavirin; Stavudine; Time Factors; Zidovudine

2005
Brain mitochondrial injury in human immunodeficiency virus-seropositive (HIV+) individuals taking nucleoside reverse transcriptase inhibitors.
    Journal of neurovirology, 2005, Volume: 11, Issue:4

    Topics: Adult; Aspartic Acid; Brain; Cell Respiration; Didanosine; Female; HIV Infections; Humans; Lamivudine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondria; Mitochondrial Diseases; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine

2005
Body fat and other metabolic effects of atazanavir and efavirenz, each administered in combination with zidovudine plus lamivudine, in antiretroviral-naive HIV-infected patients.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, Jan-15, Volume: 42, Issue:2

    Topics: Adiposity; Adult; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Oligopeptides; Oxazines; Pyridines; Zidovudine

2006
A randomized crossover study to determine bioequivalence of generic and brand name nevirapine, zidovudine, and lamivudine in HIV-negative women in India.
    Journal of acquired immune deficiency syndromes (1999), 2006, Feb-01, Volume: 41, Issue:2

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Cohort Studies; Confidence Intervals; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Female; HIV Infections; HIV Seronegativity; Humans; India; Lamivudine; Nevirapine; Tablets; Therapeutic Equivalency; Zidovudine

2006
A prospective, 96-week study of the impact of Trizivir, Combivir/nelfinavir, and lamivudine/stavudine/nelfinavir on lipids, metabolic parameters and efficacy in antiretroviral-naive patients: effect of sex and ethnicity.
    HIV medicine, 2006, Volume: 7, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Black or African American; CD4 Lymphocyte Count; Cholesterol; Dideoxynucleosides; Drug Combinations; Female; Hispanic or Latino; HIV Infections; HIV-1; Humans; Hyperlipidemias; Lactic Acid; Lamivudine; Male; Nelfinavir; Nevirapine; Prospective Studies; Sex Factors; Stavudine; Treatment Outcome; Triglycerides; Zidovudine

2006
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV.
    The New England journal of medicine, 2006, Jan-19, Volume: 354, Issue:3

    Topics: Adenine; Adolescent; Adult; Aged; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Oxazines; Prospective Studies; RNA, Viral; Tenofovir; Zidovudine

2006
An open-label, randomized comparative pilot study of a single-class quadruple therapy regimen versus a 2-class triple therapy regimen for individuals initiating antiretroviral therapy.
    Antiviral therapy, 2006, Volume: 11, Issue:1

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Organophosphonates; Oxazines; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Zidovudine

2006
[Clinical trial comparing efficacy and safety of four highly active antiretroviral therapy (HAART) in antiretroviral-naive treatment with advanced HIV infection].
    Revista clinica espanola, 2006, Volume: 206, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Didanosine; Disease Progression; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Ritonavir; Stavudine; Zidovudine

2006
Boosted versus unboosted indinavir with zidovudine and lamivudine in nucleoside pre-treated patients: a randomized, open-label trial with 112 weeks of follow-up (HIV-NAT 005).
    Antiviral therapy, 2006, Volume: 11, Issue:2

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Ritonavir; RNA, Viral; Time Factors; Viral Load; Zidovudine

2006
Virological response to a triple nucleoside/nucleotide analogue regimen over 48 weeks in HIV-1-infected adults in Africa.
    AIDS (London, England), 2006, Jun-26, Volume: 20, Issue:10

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Developing Countries; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; RNA, Viral; Tenofovir; Treatment Outcome; Uganda; Viral Load; Zidovudine; Zimbabwe

2006
Pharmacogenetic characteristics of indinavir, zidovudine, and lamivudine therapy in HIV-infected adults: a pilot study.
    Journal of acquired immune deficiency syndromes (1999), 2006, Aug-01, Volume: 42, Issue:4

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Black People; Cytochrome P-450 CYP3A; DNA Primers; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Mitochondrial Proteins; Multidrug Resistance-Associated Proteins; Pharmacogenetics; Pilot Projects; Retrospective Studies; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Zidovudine

2006
Postexposure prophylaxis for HIV in children and adolescents after sexual assault: a prospective observational study in an urban medical center.
    Sexually transmitted diseases, 2007, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Anti-HIV Agents; Child; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; New York City; Patient Compliance; Prospective Studies; Regression Analysis; Sex Offenses; Zidovudine

2007
Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana.
    AIDS (London, England), 2006, Jun-12, Volume: 20, Issue:9

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Botswana; Drug Administration Schedule; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Nevirapine; Postpartum Period; Treatment Outcome; Zidovudine

2006
Pharmacokinetics of a once-daily regimen of lopinavir/ritonavir in HIV-1-infected children.
    Antiviral therapy, 2006, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Male; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Zidovudine

2006
Initiation of antiretroviral treatment with dual nucleoside reverse transcriptase inhibitors in human immunodeficiency virus-infected infants with less advanced disease in a resource-limited setting: a multi-center study in Thailand 1998-2000.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88 Suppl 8

    Topics: Developing Countries; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine

2005
Three- vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial.
    JAMA, 2006, Aug-16, Volume: 296, Issue:7

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; RNA, Messenger; Viral Load; Zidovudine

2006
Zidovudine plus lamivudine in Human T-Lymphotropic Virus type-I-associated myelopathy: a randomised trial.
    Retrovirology, 2006, Sep-19, Volume: 3

    Topics: Aged; Anti-HIV Agents; Cell Proliferation; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; Paraparesis, Tropical Spastic; Placebos; Viral Load; Zidovudine

2006
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic, immunologic, and morphologic changes--a 96-week analysis.
    Journal of acquired immune deficiency syndromes (1999), 2006, Dec-15, Volume: 43, Issue:5

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Oxazines; RNA, Viral; Tenofovir; Time Factors; Viral Load; Zidovudine

2006
Virologic response of zidovudine, lamivudine, and tenofovir disoproxil fumarate combination in antiretroviral-naive HIV-1-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2006, Dec-15, Volume: 43, Issue:5

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Tenofovir; Viral Load; Zidovudine

2006
Triple antiretroviral prophylaxis administered during pregnancy and after delivery significantly reduces breast milk viral load: a study within the Drug Resource Enhancement Against AIDS and Malnutrition Program.
    Journal of acquired immune deficiency syndromes (1999), 2007, Mar-01, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV; HIV Infections; Humans; Lamivudine; Milk, Human; Nevirapine; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; RNA, Viral; Stavudine; Zidovudine

2007
Two-year morbidity-mortality and alternatives to prolonged breast-feeding among children born to HIV-infected mothers in Côte d'Ivoire.
    PLoS medicine, 2007, Volume: 4, Issue:1

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; Cohort Studies; Cote d'Ivoire; Female; HIV Infections; Humans; Infant; Infant Formula; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Morbidity; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Time Factors; Treatment Outcome; Zidovudine

2007
Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095).
    Journal of acquired immune deficiency syndromes (1999), 2007, Apr-15, Volume: 44, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Blood Glucose; Body Composition; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Insulin Resistance; Lactic Acid; Lamivudine; Lipids; Male; Reverse Transcriptase Inhibitors; Zidovudine

2007
Changes in the peripheral blood mtDNA levels in naive patients treated by different nucleoside reverse transcriptase inhibitor combinations and their association with subsequent lipodystrophy.
    AIDS research and human retroviruses, 2007, Volume: 23, Issue:1

    Topics: Adult; Anti-HIV Agents; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Leukocytes, Mononuclear; Logistic Models; Male; Reverse Transcriptase Inhibitors; Stavudine; Surveys and Questionnaires; Time Factors; Zidovudine

2007
Antiretroviral efficacy and virological profile of a zidovudine/lamivudine/tenofovir disoproxil fumarate combination therapy in antiretroviral-naive patients.
    Antiviral therapy, 2006, Volume: 11, Issue:6

    Topics: Adenine; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Mutation; Organophosphonates; Pilot Projects; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Treatment Outcome; Zidovudine

2006
Exploratory study comparing the metabolic toxicities of a lopinavir/ritonavir plus saquinavir dual protease inhibitor regimen versus a lopinavir/ritonavir plus zidovudine/lamivudine nucleoside regimen.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:5

    Topics: Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Pyrimidinones; Ritonavir; Saquinavir; Zidovudine

2007
Plasma HIV-1 RNA dynamics in antiretroviral-naive subjects receiving either triple-nucleoside or efavirenz-containing regimens: ACTG A5166s.
    The Journal of infectious diseases, 2007, Apr-15, Volume: 195, Issue:8

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Prospective Studies; Regression Analysis; RNA, Viral; Time Factors; Zidovudine

2007
In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children.
    AIDS (London, England), 2007, May-11, Volume: 21, Issue:8

    Topics: Anti-HIV Agents; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Reverse Transcriptase; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Maternal-Fetal Exchange; Mitochondrial Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Factors; Zidovudine

2007
Lamivudine/abacavir maintains virological superiority over zidovudine/lamivudine and zidovudine/abacavir beyond 5 years in children.
    AIDS (London, England), 2007, May-11, Volume: 21, Issue:8

    Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Dideoxynucleosides; Drug Resistance, Viral; Follow-Up Studies; Growth; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2007
Effects of potent antiretroviral therapy on free testosterone levels and fat-free mass in men in a prospective, randomized trial: A5005s, a substudy of AIDS Clinical Trials Group Study 384.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Jul-01, Volume: 45, Issue:1

    Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Didanosine; Double-Blind Method; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Nelfinavir; Prospective Studies; Stavudine; Testosterone; Zidovudine

2007
Long-term body fat outcomes in antiretroviral-naive participants randomized to nelfinavir or efavirenz or both plus dual nucleosides. Dual X-ray absorptiometry results from A5005s, a substudy of Adult Clinical Trials Group 384.
    Journal of acquired immune deficiency syndromes (1999), 2007, Aug-15, Volume: 45, Issue:5

    Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Body Composition; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Prospective Studies; Stavudine; Time Factors; Treatment Outcome; United States; Zidovudine

2007
Population pharmacokinetic analysis of lamivudine, stavudine and zidovudine in controlled HIV-infected patients on HAART.
    European journal of clinical pharmacology, 2007, Volume: 63, Issue:11

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Interactions; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Models, Biological; Nelfinavir; Reverse Transcriptase Inhibitors; Stavudine; Tissue Distribution; Zidovudine

2007
A comparison of three initial antiretroviral AIDS regimens.
    The New England journal of medicine, 2007, Sep-06, Volume: 357, Issue:10

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; HIV; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

2007
144-week data released on Gilead's study 934.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:8

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Time Factors; Viral Load; Zidovudine

2007
Pharmacokinetics of lamivudine, zidovudine, and nevirapine administered as a fixed-dose combination formulation versus coadministration of the individual products.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:11

    Topics: Adolescent; Adult; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine

2007
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis.
    Journal of acquired immune deficiency syndromes (1999), 2008, Jan-01, Volume: 47, Issue:1

    Topics: Adenine; Adult; Alkynes; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2008
Antiretroviral therapy using zidovudine, lamivudine, and efavirenz in South Africa: tolerability and clinical events.
    AIDS (London, England), 2008, Jan-02, Volume: 22, Issue:1

    Topics: Adult; Alkynes; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cohort Studies; Cyclopropanes; Developing Countries; Dizziness; Drug Tolerance; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nausea; Neutropenia; Prospective Studies; South Africa; Treatment Outcome; Viral Load; Vomiting; Zidovudine

2008
Zidovudine/lamivudine contributes to insulin resistance within 3 months of starting combination antiretroviral therapy.
    AIDS (London, England), 2008, Jan-11, Volume: 22, Issue:2

    Topics: Adiponectin; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Glucose; Glycerol; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Hyperinsulinism; Insulin Resistance; Lamivudine; Lipid Metabolism; Lipids; Lopinavir; Male; Middle Aged; Pyrimidinones; Time Factors; Treatment Outcome; Zidovudine

2008
Induction therapy with trizivir plus efavirenz or lopinavir/ritonavir followed by trizivir alone in naive HIV-1-infected adults.
    AIDS (London, England), 2008, Jan-30, Volume: 22, Issue:3

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Failure; Treatment Outcome; Zidovudine

2008
Lopinavir/ritonavir monotherapy or plus zidovudine and lamivudine in antiretroviral-naive HIV-infected patients.
    AIDS (London, England), 2008, Jan-30, Volume: 22, Issue:3

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease; HIV-1; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2008
Twenty-four-week safety and tolerability of nevirapine vs. abacavir in combination with zidovudine/lamivudine as first-line antiretroviral therapy: a randomized double-blind trial (NORA).
    Tropical medicine & international health : TM & IH, 2008, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Treatment Outcome; Uganda; Zidovudine

2008
Tolerability and effectiveness of first-line regimens combining nevirapine and lamivudine plus zidovudine or stavudine in Cameroon.
    AIDS research and human retroviruses, 2008, Volume: 24, Issue:3

    Topics: Adult; Anemia; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Multivariate Analysis; Nevirapine; Patient Compliance; Peripheral Nervous System Diseases; Prospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2008
Effect of maraviroc on the pharmacokinetics of midazolam, lamivudine/zidovudine, and ethinyloestradiol/levonorgestrel in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Anti-HIV Agents; CCR5 Receptor Antagonists; Contraceptives, Oral; Cyclohexanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Ethinyl Estradiol; Female; HIV Infections; Humans; Lamivudine; Levonorgestrel; Male; Maraviroc; Midazolam; Middle Aged; Statistics as Topic; Triazoles; Zidovudine

2008
Absence of HIV-1 shedding in male genital tract after 1 year of first-line lopinavir/ritonavir alone or in combination with zidovudine/lamivudine.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:6

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Genitalia, Male; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Lopinavir; Male; Plasma; Pyrimidinones; Ritonavir; RNA, Viral; Semen; Time Factors; Virus Shedding; Zidovudine

2008
Pharmacokinetics of zidovudine and lamivudine during oral uridine supplementation with NucleomaxX.
    Journal of acquired immune deficiency syndromes (1999), 2008, May-01, Volume: 48, Issue:1

    Topics: Administration, Oral; Area Under Curve; Double-Blind Method; Female; HIV Infections; Humans; Lamivudine; Male; Placebos; Reverse Transcriptase Inhibitors; Uridine; Zidovudine

2008
Long-term subcutaneous tissue changes among antiretroviral-naive persons initiating stavudine, zidovudine, or abacavir with lamivudine.
    Journal of acquired immune deficiency syndromes (1999), 2008, May-01, Volume: 48, Issue:1

    Topics: Adult; Cohort Studies; Dideoxynucleosides; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Subcutaneous Fat; Zidovudine

2008
Antiviral activity and safety of aplaviroc with lamivudine/zidovudine in HIV-infected, therapy-naive patients: the ASCENT (CCR102881) study.
    Antiviral therapy, 2008, Volume: 13, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Benzoates; Diketopiperazines; Double-Blind Method; Drug Therapy, Combination; Female; HIV Fusion Inhibitors; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Piperazines; Reverse Transcriptase Inhibitors; Spiro Compounds; Treatment Outcome; Zidovudine

2008
Changes in antioxidant profile among HIV-infected individuals on generic highly active antiretroviral therapy in southern India.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2008, Volume: 12, Issue:6

    Topics: Adult; Albumins; Alkynes; Anti-HIV Agents; Antioxidants; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Drugs, Generic; Female; Glutathione Peroxidase; Glutathione Reductase; HIV Infections; Humans; India; Lamivudine; Male; Oxidative Stress; Reverse Transcriptase Inhibitors; Stavudine; Uric Acid; Young Adult; Zidovudine

2008
Clinical trial: randomized controlled study of zidovudine and lamivudine for patients with primary biliary cirrhosis stabilized on ursodiol.
    Alimentary pharmacology & therapeutics, 2008, Oct-01, Volume: 28, Issue:7

    Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Antiviral Agents; Aspartate Aminotransferases; Betaretrovirus; Cholagogues and Choleretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamivudine; Liver Cirrhosis, Biliary; Male; Middle Aged; Retroviridae Infections; Treatment Outcome; Tumor Virus Infections; Ursodeoxycholic Acid; Zidovudine

2008
Zidovudine/lamivudine/abacavir plus tenofovir in HIV-infected naive patients: a 96-week prospective one-arm pilot study.
    AIDS research and human retroviruses, 2008, Volume: 24, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Endpoint Determination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Prospective Studies; Spain; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2008
Effect of lopinavir/ritonavir monotherapy on quality of life and self-reported symptoms among antiretroviral-naive patients: results of the MONARK trial.
    Antiviral therapy, 2008, Volume: 13, Issue:4

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Pyrimidinones; Quality of Life; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Viral Load; Zidovudine

2008
Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s.
    Journal of the American College of Cardiology, 2008, Aug-12, Volume: 52, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Brachial Artery; CD4 Lymphocyte Count; Cyclopropanes; Endothelium, Vascular; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Tenofovir; Time Factors; Zidovudine

2008
A randomized trial of combination hepatitis B therapy in HIV/HBV coinfected antiretroviral naïve individuals in Thailand.
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:4

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; DNA, Viral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir; Thailand; Treatment Outcome; Zidovudine

2008
Didanosine, lamivudine, and efavirenz versus zidovudine, lamivudine, and efavirenz for the initial treatment of HIV type 1 infection: final analysis (48 weeks) of a prospective, randomized, noninferiority clinical trial, GESIDA 3903.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Oct-15, Volume: 47, Issue:8

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; RNA, Viral; Severity of Illness Index; Treatment Outcome; Viral Load; Zidovudine

2008
Phase II study of vicriviroc versus efavirenz (both with zidovudine/lamivudine) in treatment-naive subjects with HIV-1 infection.
    The Journal of infectious diseases, 2008, Oct-15, Volume: 198, Issue:8

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Piperazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2008
Highly active antiretroviral therapy versus zidovudine/nevirapine effects on early breast milk HIV type-1 Rna: a phase II randomized clinical trial.
    Antiviral therapy, 2008, Volume: 13, Issue:6

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral; Treatment Outcome; Zidovudine

2008
Early antiretroviral therapy and mortality among HIV-infected infants.
    The New England journal of medicine, 2008, Nov-20, Volume: 359, Issue:21

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; Treatment Failure; Zidovudine

2008
Development of fixed dose combination tablets containing zidovudine and lamivudine for paediatric applications.
    International journal of pharmaceutics, 2009, Mar-31, Volume: 370, Issue:1-2

    Topics: Adult; Anti-HIV Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Compounding; Female; Humans; Lamivudine; Male; Middle Aged; Pediatrics; Reverse Transcriptase Inhibitors; Solubility; Tablets; Zidovudine

2009
Virologic failure in first-line human immunodeficiency virus therapy with a CCR5 entry inhibitor, aplaviroc, plus a fixed-dose combination of lamivudine-zidovudine: nucleoside reverse transcriptase inhibitor resistance regardless of envelope tropism.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Anti-HIV Agents; Benzoates; Diketopiperazines; Drug Combinations; Drug Resistance, Viral; env Gene Products, Human Immunodeficiency Virus; HIV Infections; HIV-1; Humans; Lamivudine; Phylogeny; Piperazines; Receptors, CCR5; Reverse Transcriptase Inhibitors; Spiro Compounds; Treatment Failure; Tropism; Zidovudine

2009
A randomized, open-label study of a nucleoside analogue reverse transcriptase inhibitor-sparing regimen in antiretroviral-naive HIV-infected patients.
    Journal of acquired immune deficiency syndromes (1999), 2009, Mar-01, Volume: 50, Issue:3

    Topics: Adult; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Male; Nevirapine; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine

2009
Predictors of loss of virologic response in subjects who simplified to lopinavir/ritonavir monotherapy from lopinavir/ritonavir plus zidovudine/lamivudine.
    AIDS research and human retroviruses, 2009, Volume: 25, Issue:3

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Medication Adherence; Plasma; Pyrimidinones; Ritonavir; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2009
First line zidovudine/lamivudine/lopinavir/ritonavir leads to greater bone loss compared to nevirapine/lopinavir/ritonavir.
    AIDS (London, England), 2009, Jul-17, Volume: 23, Issue:11

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Osteoporosis; Pyrimidinones; Ritonavir; Young Adult; Zidovudine

2009
Protease inhibitor resistance analysis in the MONARK trial comparing first-line lopinavir-ritonavir monotherapy to lopinavir-ritonavir plus zidovudine and lamivudine triple therapy.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Drug Resistance, Viral; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Pyrimidinones; Ritonavir; Treatment Outcome; Zidovudine

2009
Zidovudine/lamivudine for HIV-1 infection contributes to limb fat loss.
    PloS one, 2009, May-21, Volume: 4, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Biomarkers; Body Composition; Glucose; HIV Infections; HIV-1; Humans; Lamivudine; Lipids; Lipodystrophy; Lopinavir; Male; Middle Aged; Pyrimidinones; Zidovudine

2009
Loss of bone mineral density after antiretroviral therapy initiation, independent of antiretroviral regimen.
    Journal of acquired immune deficiency syndromes (1999), 2009, Aug-15, Volume: 51, Issue:5

    Topics: Absorptiometry, Photon; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Bone Density; Cyclopropanes; Female; HIV Infections; Humans; Inflammation Mediators; Lamivudine; Lopinavir; Male; Middle Aged; Osteoporosis; Prospective Studies; Pyrimidinones; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Risk Factors; Ritonavir; Zidovudine

2009
Switch from a ZDV/3TC-based regimen to a completely once daily (QD) regimen of emtricitabine/tenofovir DF fixed dose combination plus a third QD agent (SONETT).
    European journal of medical research, 2009, May-14, Volume: 14, Issue:5

    Topics: Adenine; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Emtricitabine; Female; Hemoglobins; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load; Young Adult; Zidovudine

2009
A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals.
    Journal of acquired immune deficiency syndromes (1999), 2009, Aug-15, Volume: 51, Issue:5

    Topics: Adenine; Adipose Tissue; Adult; Aged; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Extremities; Female; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lipids; Male; Middle Aged; Organophosphonates; Tenofovir; Young Adult; Zidovudine

2009
Modulation of K65R selection by zidovudine inclusion: analysis of HIV resistance selection in subjects with virologic failure receiving once-daily abacavir/lamivudine/zidovudine and tenofovir DF (study COL40263).
    AIDS research and human retroviruses, 2009, Volume: 25, Issue:7

    Topics: Adenine; Adult; Amino Acid Substitution; Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; RNA, Viral; Tenofovir; Treatment Failure; Zidovudine

2009
Interindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidation.
    Journal of clinical pharmacology, 2009, Volume: 49, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Female; Ghana; Glucuronides; Glucuronosyltransferase; Half-Life; HIV Infections; Humans; Lamivudine; Liver; Male; Middle Aged; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Stavudine; Tuberculosis; Zidovudine

2009
Development of HIV-1 drug resistance through 144 weeks in antiretroviral-naïve subjects on emtricitabine, tenofovir disoproxil fumarate, and efavirenz compared with lamivudine/zidovudine and efavirenz in study GS-01-934.
    Journal of acquired immune deficiency syndromes (1999), 2009, Oct-01, Volume: 52, Issue:2

    Topics: Adenine; Alkynes; Amino Acid Substitution; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genome, Viral; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Mutation, Missense; Organophosphonates; Tenofovir; Treatment Failure; Zidovudine

2009
Long-term (96-week) follow-up of antiretroviral-naïve HIV-infected patients treated with first-line lopinavir/ritonavir monotherapy in the MONARK trial.
    HIV medicine, 2010, Volume: 11, Issue:2

    Topics: Antiretroviral Therapy, Highly Active; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Intention to Treat Analysis; Lamivudine; Lopinavir; Male; Medication Adherence; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome; Zidovudine

2010
96-Week MERIT ES analysis shows efficacy of Celsentri=Selzentry.
    AIDS patient care and STDs, 2009, Volume: 23, Issue:8

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Maraviroc; Reverse Transcriptase Inhibitors; Time Factors; Treatment Outcome; Triazoles; Zidovudine

2009
Pharmacokinetics and 48 week efficacy of low-dose lopinavir/ritonavir in HIV-infected children.
    The Journal of antimicrobial chemotherapy, 2009, Volume: 64, Issue:5

    Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Plasma; Pyrimidinones; Ritonavir; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2009
Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trial.
    PLoS medicine, 2009, Volume: 6, Issue:10

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Viral Load; Zidovudine

2009
Insulin sensitivity in multiple pathways is differently affected during zidovudine/lamivudine-containing compared with NRTI-sparing combination antiretroviral therapy.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 53, Issue:2

    Topics: Adult; Anti-HIV Agents; Blood Glucose; Body Composition; Drug Therapy, Combination; HIV Infections; Humans; Insulin Resistance; Intra-Abdominal Fat; Lamivudine; Lipids; Lipolysis; Liver; Male; Middle Aged; Zidovudine

2010
Viral rebound and emergence of drug resistance in the absence of viral load testing: a randomized comparison between zidovudine-lamivudine plus Nevirapine and zidovudine-lamivudine plus Abacavir.
    The Journal of infectious diseases, 2010, Jan-01, Volume: 201, Issue:1

    Topics: Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Mutation; Nevirapine; RNA, Viral; Uganda; Viral Load; Zidovudine

2010
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
    Lancet (London, England), 2009, Dec-19, Volume: 374, Issue:9707

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine

2009
Early versus delayed fixed dose combination abacavir/lamivudine/zidovudine in patients with HIV and tuberculosis in Tanzania.
    AIDS research and human retroviruses, 2009, Volume: 25, Issue:12

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Male; Pilot Projects; Tanzania; Tuberculosis; Viral Load; Zidovudine

2009
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial.
    Lancet (London, England), 2010, Jan-09, Volume: 375, Issue:9709

    Topics: Adenine; Adolescent; Adult; Africa; Aged; Anemia; Anti-Retroviral Agents; CD4 Lymphocyte Count; Creatinine; Dideoxynucleosides; Disease Progression; Drug Monitoring; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Middle Aged; Neutropenia; Neutrophils; Nevirapine; Organophosphonates; RNA, Viral; Tenofovir; Urea; Viral Load; Zidovudine

2010
Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months.
    Antiviral therapy, 2009, Volume: 14, Issue:8

    Topics: Adenine; Adipocytes; Adipose Tissue; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cell Differentiation; Cyclopropanes; Drug Therapy, Combination; Fatty Acids; Female; Gene Expression; Genes, Mitochondrial; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Male; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Up-Regulation; Zidovudine

2009
The impact of once-nightly versus twice-daily dosing and baseline beliefs about HAART on adherence to efavirenz-based HAART over 48 weeks: the NOCTE study.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 53, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Culture; Cyclopropanes; Didanosine; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Surveys and Questionnaires; Zidovudine

2010
Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts.
    HIV medicine, 2010, Volume: 11, Issue:5

    Topics: Adult; Body Weight; CD4 Lymphocyte Count; Dideoxynucleosides; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Nevirapine; Recurrence; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Uganda; Viral Load; Zidovudine

2010
Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection.
    The Journal of infectious diseases, 2010, Mar-15, Volume: 201, Issue:6

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Antiviral Agents; Benzoxazines; CCR5 Receptor Antagonists; Cyclohexanes; Cyclopropanes; Double-Blind Method; Drug Combinations; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Maraviroc; Middle Aged; Receptors, CCR5; Treatment Outcome; Triazoles; Viral Load; Viral Tropism; Young Adult; Zidovudine

2010
Lack of minority K65R-resistant viral populations detected after repeated treatment interruptions of tenofovir/zidovudine and lamivudine in a resource-limited setting.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 54, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Viral Load; Zidovudine

2010
Abacavir/lamivudine/zidovudine maintenance after standard induction in antiretroviral therapy-naïve patients: FREE randomized trial interim results.
    AIDS patient care and STDs, 2010, Volume: 24, Issue:6

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Young Adult; Zidovudine

2010
Maternal or infant antiretroviral drugs to reduce HIV-1 transmission.
    The New England journal of medicine, 2010, Jun-17, Volume: 362, Issue:24

    Topics: Adult; Anti-Retroviral Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV Infections; HIV Seronegativity; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Kaplan-Meier Estimate; Lamivudine; Male; Neutropenia; Nevirapine; Pregnancy; Risk Factors; Stevens-Johnson Syndrome; Young Adult; Zidovudine

2010
Bone mineral density changes in protease inhibitor-sparing vs. nucleoside reverse transcriptase inhibitor-sparing highly active antiretroviral therapy: data from a randomized trial.
    HIV medicine, 2011, Volume: 12, Issue:3

    Topics: Absorptiometry, Photon; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Bone Density; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; Zidovudine

2011
Safety and effectiveness of antiretroviral drugs during pregnancy, delivery and breastfeeding for prevention of mother-to-child transmission of HIV-1: the Kesho Bora Multicentre Collaborative Study rationale, design, and implementation challenges.
    Contemporary clinical trials, 2011, Volume: 32, Issue:1

    Topics: Africa, Eastern; Africa, Southern; Africa, Western; Anti-Retroviral Agents; Breast Feeding; Child, Preschool; Clinical Protocols; Cohort Studies; Delivery, Obstetric; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Mothers; Nevirapine; Pregnancy; Pyrimidinones; Research Design; Ritonavir; Zidovudine

2011
A randomized factorial trial comparing 4 treatment regimens in treatment-naive HIV-infected persons with AIDS and/or a CD4 cell count <200 cells/μL in South Africa.
    The Journal of infectious diseases, 2010, Nov-15, Volume: 202, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Ritonavir; RNA, Viral; South Africa; Stavudine; Treatment Outcome; Zidovudine

2010
Long-term effectiveness and safety of didanosine combined with lamivudine and efavirenz or nevirapine in antiretroviral-naive patients: a 9-year cohort study in Senegal.
    Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Treatment Outcome; Viral Load; Zidovudine

2011
Evaluation of steady-state pharmacokinetic interactions between ritonavir-boosted BILR 355, a non-nucleoside reverse transcriptase inhibitor, and lamivudine/zidovudine in healthy subjects.
    Journal of clinical pharmacy and therapeutics, 2012, Volume: 37, Issue:1

    Topics: Adult; Anti-HIV Agents; Area Under Curve; Azepines; Drug Combinations; Drug Interactions; Female; Half-Life; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Young Adult; Zidovudine

2012
Fat tissue distribution changes in HIV-infected patients treated with lopinavir/ritonavir. Results of the MONARK trial.
    Current HIV research, 2011, Volume: 9, Issue:1

    Topics: Absorptiometry, Photon; Adult; Anti-HIV Agents; Body Fat Distribution; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Pyrimidinones; Ritonavir; Zidovudine

2011
Beliefs about antiretroviral therapy, treatment adherence and quality of life in a 48-week randomised study of continuation of zidovudine/lamivudine or switch to tenofovir DF/emtricitabine, each with efavirenz.
    AIDS care, 2011, Volume: 23, Issue:6

    Topics: Adenine; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Substitution; Drug Therapy, Combination; Emtricitabine; Female; Health Knowledge, Attitudes, Practice; HIV Infections; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Organophosphonates; Quality of Life; Tenofovir; Treatment Outcome; Young Adult; Zidovudine

2011
Timing of initiation of antiretroviral therapy in human immunodeficiency virus (HIV)--associated tuberculous meningitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011, Volume: 52, Issue:11

    Topics: Adult; Alkynes; Anti-HIV Agents; Anti-Inflammatory Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; Benzoxazines; Cyclopropanes; Dexamethasone; Double-Blind Method; Female; HIV Infections; Humans; Lamivudine; Male; Placebos; Time Factors; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Meningeal; Zidovudine

2011
Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; HIV Infections; Lamivudine; Lopinavir; Protease Inhibitors; Ritonavir; Stavudine; Zidovudine

2011
Residual activity of two HIV antiretroviral regimens prescribed without virological monitoring.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Lamivudine; Nevirapine; RNA, Viral; Viral Load; Zidovudine

2011
A randomized trial of punctuated antiretroviral therapy in Ugandan HIV-seropositive adults with pulmonary tuberculosis and CD4⁺ T-cell counts of ≥ 350 cells/μL.
    The Journal of infectious diseases, 2011, Sep-15, Volume: 204, Issue:6

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antitubercular Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Dideoxynucleosides; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Survival Analysis; Treatment Outcome; Tuberculosis, Pulmonary; Uganda; Young Adult; Zidovudine

2011
Glomerular dysfunction and associated risk factors over 4-5 years following antiretroviral therapy initiation in Africa.
    Antiviral therapy, 2011, Volume: 16, Issue:7

    Topics: Adenine; Adult; Africa; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Creatinine; Dideoxynucleosides; Female; Glomerular Filtration Rate; HIV Infections; Humans; Kidney Diseases; Kidney Glomerulus; Lamivudine; Male; Nevirapine; Organophosphonates; Risk Factors; Tenofovir; Time Factors; Zidovudine

2011
Pharmacokinetics and safety of a new paediatric fixed-dose combination of zidovudine/lamivudine/nevirapine in HIV-infected children.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Anti-HIV Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biological Availability; Body Weight; Child; Child, Preschool; Cytochrome P-450 CYP2B6; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Oxidoreductases, N-Demethylating; Reverse Transcriptase Inhibitors; Tablets; Zidovudine

2011
Short-course Combivir after single-dose nevirapine reduces but does not eliminate the emergence of nevirapine resistance in women.
    Antiviral therapy, 2012, Volume: 17, Issue:2

    Topics: Anti-HIV Agents; Drug Combinations; Drug Resistance, Viral; Female; Genotype; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral; Viral Load; Zidovudine

2012
Post-exposure prophylaxis for HIV infection: a clinical trial comparing lopinavir/ritonavir versus atazanavir each with zidovudine/lamivudine.
    Antiviral therapy, 2012, Volume: 17, Issue:2

    Topics: Adult; Anti-HIV Agents; Atazanavir Sulfate; Drug Combinations; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Oligopeptides; Post-Exposure Prophylaxis; Pyridines; Ritonavir; Zidovudine

2012
Effect of gender and race on the week 48 findings in treatment-naïve, HIV-1-infected patients enrolled in the randomized, phase III trials ECHO and THRIVE.
    HIV medicine, 2012, Volume: 13, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Black or African American; CD4 Lymphocyte Count; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Sex Factors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2012
A comparison of measured and estimated glomerular filtration rate in successfully treated HIV-patients with preserved renal function.
    Clinical nephrology, 2012, Volume: 77, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Body Mass Index; Deoxycytidine; Emtricitabine; Female; Glomerular Filtration Rate; HIV Infections; Humans; Lamivudine; Linear Models; Male; Middle Aged; Netherlands; Organophosphonates; Pilot Projects; Research Design; Statistics, Nonparametric; Tenofovir; Treatment Outcome; Zidovudine

2012
Maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission: 48-week follow-up of the BAN randomised controlled trial.
    Lancet (London, England), 2012, Jun-30, Volume: 379, Issue:9835

    Topics: Adult; Anti-Retroviral Agents; Breast Feeding; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Young Adult; Zidovudine

2012
Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial.
    PLoS medicine, 2012, Volume: 9, Issue:5

    Topics: Abortion, Spontaneous; Adenine; Adult; Anti-HIV Agents; Body Height; Body Weight; Breast Feeding; Burns; Cause of Death; Child, Preschool; Congenital Abnormalities; Drug Combinations; Female; Follow-Up Studies; Fractures, Bone; Growth; HIV Infections; HIV Seropositivity; Humans; Infant; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Measles; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prevalence; Respiratory Tract Infections; Tenofovir; Uganda; Zidovudine; Zimbabwe

2012
Three postpartum antiretroviral regimens to prevent intrapartum HIV infection.
    The New England journal of medicine, 2012, Jun-21, Volume: 366, Issue:25

    Topics: Anti-Retroviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant Formula; Infant, Newborn; Infectious Disease Transmission, Vertical; Kaplan-Meier Estimate; Lamivudine; Male; Nelfinavir; Nevirapine; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2012
Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children.
    The New England journal of medicine, 2012, Jun-21, Volume: 366, Issue:25

    Topics: Anti-Retroviral Agents; CD4 Lymphocyte Count; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Kaplan-Meier Estimate; Lamivudine; Lopinavir; Male; Nevirapine; Ritonavir; RNA, Viral; Zidovudine

2012
Treatment outcomes among HIV-1 and HIV-2 infected children initiating antiretroviral therapy in a concentrated low prevalence setting in West Africa.
    BMC pediatrics, 2012, Jul-08, Volume: 12

    Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; Gambia; HIV Infections; HIV-1; HIV-2; Humans; Infant; Kaplan-Meier Estimate; Lamivudine; Lopinavir; Male; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Treatment Outcome; Viral Load; Zidovudine

2012
Zidovudine/lamivudine but not nevirapine in combination with lopinavir/ritonavir decreases subcutaneous adipose tissue mitochondrial DNA.
    AIDS (London, England), 2012, Nov-13, Volume: 26, Issue:17

    Topics: Absorptiometry, Photon; Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Anti-HIV Agents; Atrophy; CD4 Lymphocyte Count; DNA, Mitochondrial; Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Prospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Subcutaneous Fat; Treatment Outcome; Young Adult; Zidovudine

2012
Population-based sequencing of the V3-loop can predict the virological response to maraviroc in treatment-naive patients of the MERIT trial.
    Journal of acquired immune deficiency syndromes (1999), 2012, Nov-01, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Cyclohexanes; Drug Combinations; Drug Therapy, Combination; Female; Genotype; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Male; Maraviroc; Middle Aged; Polymerase Chain Reaction; Retrospective Studies; Sequence Analysis, DNA; Triazoles; Viral Load; Viral Tropism; Young Adult; Zidovudine

2012
Anaemia in HIV-infected children: severity, types and effect on response to HAART.
    BMC pediatrics, 2012, Oct-31, Volume: 12

    Topics: Adolescent; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Cross-Sectional Studies; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Logistic Models; Male; Nevirapine; Prevalence; Prospective Studies; Severity of Illness Index; Treatment Outcome; Uganda; Zidovudine

2012
Therapeutic levels of lopinavir in late pregnancy and abacavir passage into breast milk in the Mma Bana Study, Botswana.
    Antiviral therapy, 2013, Volume: 18, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Botswana; Breast Feeding; Dideoxynucleosides; Female; HIV Infections; HIV-1; Humans; Infant; Lactation; Lamivudine; Lopinavir; Middle Aged; Milk, Human; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine

2013
A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine.
    Antiviral therapy, 2012, Volume: 17, Issue:8

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Diet; Drug Administration Schedule; Drug Substitution; Female; Glomerular Filtration Rate; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Peripheral Nervous System Diseases; Stavudine; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2012
Pharmacokinetic interactions between lersivirine and zidovudine, tenofovir disoproxil fumarate/emtricitabine and abacavir/lamivudine.
    Antiviral therapy, 2013, Volume: 18, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Interactions; Emtricitabine; Female; Healthy Volunteers; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nitriles; Organophosphonates; Pyrazoles; Tenofovir; Young Adult; Zidovudine

2013
A randomized pahse I bioequivalence clinincal trial of a paediatric fixed-dose combination antiretroviral reconstitutable suspension in healthy adult volunteers.
    Antiviral therapy, 2013, Volume: 18, Issue:2

    Topics: Adult; Anti-HIV Agents; Cross-Over Studies; Drug Combinations; Female; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Therapeutic Equivalency; Young Adult; Zidovudine

2013
Health outcomes of HIV-exposed uninfected African infants.
    AIDS (London, England), 2013, Mar-13, Volume: 27, Issue:5

    Topics: Anti-Retroviral Agents; Antiviral Agents; Breast Feeding; Cause of Death; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Infant; Infant Mortality; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Malawi; Morbidity; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Proportional Hazards Models; Zidovudine

2013
A simplified combination antiretroviral therapy regimen enhances adherence, treatment satisfaction and quality of life: results of a randomized clinical trial.
    HIV medicine, 2014, Volume: 15, Issue:5

    Topics: Adult; Antiretroviral Therapy, Highly Active; Belgium; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Medication Adherence; Middle Aged; Netherlands; Odds Ratio; Patient Satisfaction; Quality of Life; Ritonavir; Zidovudine

2014
High rate of HIV resuppression after viral failure on first-line antiretroviral therapy in the absence of switch to second-line therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Volume: 58, Issue:7

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Nevirapine; Viral Load; Viremia; Zidovudine

2014
Effectiveness of option B highly active antiretroviral therapy (HAART) prevention of mother-to-child transmission (PMTCT) in pregnant HIV women.
    BMC research notes, 2014, Jan-21, Volume: 7

    Topics: Administration, Oral; Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Counseling; Drug Administration Schedule; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Infusions, Intravenous; Kenya; Lamivudine; Medication Adherence; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Socioeconomic Factors; Viral Load; Viremia; Young Adult; Zidovudine

2014
High level of viral suppression and low switch rate to second-line antiretroviral therapy among HIV-infected adult patients followed over five years: retrospective analysis of the DART trial.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cross-Sectional Studies; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Probability; Retrospective Studies; RNA, Viral; Tenofovir; Uganda; Viral Load; Zidovudine

2014
Anthropometric measurements and lipid profiles to detect early lipodystrophy in antiretroviral therapy experienced HIV-infected children in the CHAPAS-3 trial.
    Antiviral therapy, 2014, Volume: 19, Issue:3

    Topics: Anthropometry; Anti-HIV Agents; Child; Child, Preschool; Cross-Sectional Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lipid Metabolism; Lipodystrophy; Lipoproteins, HDL; Lipoproteins, LDL; Male; Nevirapine; Stavudine; Triglycerides; Viral Load; Zidovudine

2014
Lipid levels and changes in body fat distribution in treatment-naive, HIV-1-Infected adults treated with rilpivirine or Efavirenz for 96 weeks in the ECHO and THRIVE trials.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Aug-01, Volume: 59, Issue:3

    Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Aged, 80 and over; Alkynes; Anti-HIV Agents; Benzoxazines; Body Fat Distribution; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Young Adult; Zidovudine

2014
Relationship of vitamin D insufficiency to AIDS-associated Kaposi's sarcoma outcomes: retrospective analysis of a prospective clinical trial in Zimbabwe.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 24

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Dideoxynucleosides; Disease Progression; Female; Herpesvirus 8, Human; HIV-1; Humans; Lamivudine; Male; Middle Aged; Odds Ratio; Pilot Projects; Prospective Studies; RNA, Viral; Sarcoma, Kaposi; Survival Analysis; Treatment Outcome; Vitamin D; Vitamin D Deficiency; Zidovudine; Zimbabwe

2014
First-line antiretroviral therapy with nevirapine versus lopinavir-ritonavir based regimens in a resource-limited setting.
    AIDS (London, England), 2014, May-15, Volume: 28, Issue:8

    Topics: Adenine; Adult; CD4 Lymphocyte Count; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Organophosphonates; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2014
Efficacy and safety of darunavir/ritonavir at 48 weeks in treatment-naïve, HIV-1-infected adolescents: results from a phase 2 open-label trial (DIONE).
    The Pediatric infectious disease journal, 2014, Volume: 33, Issue:9

    Topics: Adolescent; Anemia; CD4 Lymphocyte Count; Darunavir; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Nausea; Neutropenia; Reverse Transcriptase Inhibitors; Ritonavir; Sulfonamides; Time Factors; Viral Load; Vomiting; Zidovudine

2014
Pre-antiretroviral therapy serum selenium concentrations predict WHO stages 3, 4 or death but not virologic failure post-antiretroviral therapy.
    Nutrients, 2014, Nov-13, Volume: 6, Issue:11

    Topics: Adult; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Body Mass Index; C-Reactive Protein; CD4 Lymphocyte Count; Cyclopropanes; Deoxycytidine; Didanosine; Disease Progression; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Multivariate Analysis; Oligopeptides; Prospective Studies; Pyridines; Risk Factors; Selenium; World Health Organization; Zidovudine

2014
A randomized controlled trial of single-class maintenance therapy with abacavir/lamivudine/zidovudine after standard triple antiretroviral induction therapy: final 96-week results from the FREE study.
    HIV medicine, 2015, Volume: 16, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Belgium; CD4 Lymphocyte Count; Clinical Protocols; Dideoxynucleosides; Disease Progression; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lipids; Male; Middle Aged; Netherlands; Prospective Studies; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2015
Switching from zidovudine/lamivudine to tenofovir/emtricitabine improves fat distribution as measured by fat mass ratio.
    HIV medicine, 2015, Volume: 16, Issue:6

    Topics: Absorptiometry, Photon; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Fat Distribution; Drug Combinations; Drug Substitution; Emtricitabine; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Regression Analysis; Tenofovir; Zidovudine

2015
In utero exposure to zidovudine and heart anomalies in the ANRS French perinatal cohort and the nested PRIMEVA randomized trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Jul-15, Volume: 61, Issue:2

    Topics: Adult; Anti-HIV Agents; Drug Combinations; Echocardiography; Female; Follow-Up Studies; France; Heart Defects, Congenital; Heart Septal Defects, Ventricular; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Sex Factors; Uterus; Young Adult; Zidovudine

2015
Dual treatment with atazanavir-ritonavir plus lamivudine versus triple treatment with atazanavir-ritonavir plus two nucleos(t)ides in virologically stable patients with HIV-1 (SALT): 48 week results from a randomised, open-label, non-inferiority trial.
    The Lancet. Infectious diseases, 2015, Volume: 15, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Deoxycytidine; Drug Substitution; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oligopeptides; Organophosphonates; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Tenofovir; Viral Load; Zidovudine

2015
Safety of zidovudine dose reduction in treatment-naïve HIV infected patients. A randomized controlled study (MiniZID).
    HIV medicine, 2016, Volume: 17, Issue:3

    Topics: Adult; Anemia; Anti-HIV Agents; Cameroon; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; Treatment Outcome; Zidovudine

2016
Abacavir, zidovudine, or stavudine as paediatric tablets for African HIV-infected children (CHAPAS-3): an open-label, parallel-group, randomised controlled trial.
    The Lancet. Infectious diseases, 2016, Volume: 16, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Stavudine; Tablets; Uganda; Zambia; Zidovudine

2016
Contribution of different antiretroviral regimens containing zidovudine, lamivudine and ritonavir-boosted lopinavir on HIV viral load reduction during pregnancy.
    Antiviral therapy, 2016, Volume: 21, Issue:5

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Ritonavir; Thailand; Viral Load; Zidovudine

2016
In vitro-in vivo Pharmacokinetic correlation model for quality assurance of antiretroviral drugs.
    Colombia medica (Cali, Colombia), 2015, Sep-30, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Caco-2 Cells; Humans; Lamivudine; Male; Models, Biological; Permeability; Rabbits; Solubility; Species Specificity; Stavudine; Young Adult; Zidovudine

2015
Bleeding patterns of HIV-infected women using an etonogestrel-releasing contraceptive implant and efavirenz-based or lopinavir/ritonavir-based antiretroviral therapy.
    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2016, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Alkynes; Amenorrhea; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Desogestrel; Drug Combinations; Drug Implants; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Metrorrhagia; Prospective Studies; Ritonavir; Young Adult; Zidovudine

2016
Efficacy and safety of tenofovir-containing antiretroviral therapy in women who acquired HIV while enrolled in tenofovir gel prophylaxis trials.
    Antiviral therapy, 2017, Volume: 22, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Emtricitabine; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Patient Safety; Pregnancy; Primary Prevention; RNA, Viral; South Africa; Tenofovir; Treatment Outcome; Vaginal Creams, Foams, and Jellies; Viral Load; Zidovudine

2017
A randomized two-way crossover bioequivalence study in healthy adult volunteers of paediatric zidovudine/lamivudine/nevirapine fast-disintegrating fixed-dose combination tablet.
    The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:4

    Topics: Adult; Cross-Over Studies; Drug Combinations; Female; Healthy Volunteers; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Solubility; Tablets; Therapeutic Equivalency; Young Adult; Zidovudine

2017
Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor- Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Antimalarials; CD4 Lymphocyte Count; Child; Child, Preschool; Coinfection; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Malaria, Falciparum; Malawi; Male; Nevirapine; Plasmodium falciparum; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine

2016
Insulin-Like Growth Factor Is Associated with Changes in Body Composition with Antiretroviral Therapy Initiation.
    AIDS research and human retroviruses, 2017, Volume: 33, Issue:9

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Body Composition; Cyclopropanes; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Insulin-Like Growth Factor I; Lamivudine; Male; Prospective Studies; Tenofovir; Zidovudine

2017
Assessment of Nevirapine Prophylactic and Therapeutic Dosing Regimens for Neonates.
    Journal of acquired immune deficiency syndromes (1999), 2017, 08-15, Volume: 75, Issue:5

    Topics: Anti-HIV Agents; Breast Feeding; Chemoprevention; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Thailand; World Health Organization; Zidovudine

2017
Variability of efavirenz plasma concentrations among pediatric HIV patients treated with efavirenz based combination antiretroviral therapy in Dar es Salaam, Tanzania.
    BMC pharmacology & toxicology, 2018, Oct-23, Volume: 19, Issue:1

    Topics: Adolescent; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Biological Variation, Population; Child; Child, Preschool; Cyclopropanes; Drug Monitoring; Female; HIV Infections; Humans; Lamivudine; Male; Tanzania; Zidovudine

2018
Association between HIV antiretroviral therapy and preterm birth based on antenatal ultrasound gestational age determination: a comparative analysis.
    AIDS (London, England), 2019, 12-01, Volume: 33, Issue:15

    Topics: Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Emtricitabine; Female; Gestational Age; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Lopinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Premature Birth; Risk; Ritonavir; Tenofovir; Ultrasonography, Prenatal; Young Adult; Zidovudine

2019
Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial.
    The lancet. HIV, 2020, Volume: 7, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Integrase Inhibitors; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Outcome Assessment, Health Care; Pregnancy; Pregnancy Complications, Infectious; Raltegravir Potassium; Viral Load; Young Adult; Zidovudine

2020
Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092.
    The Pediatric infectious disease journal, 2021, 05-01, Volume: 40, Issue:5

    Topics: Africa South of the Sahara; Anti-HIV Agents; Area Under Curve; Child, Preschool; Chromatography, Liquid; Cohort Studies; Drug Combinations; Drug Elimination Routes; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Lopinavir; Male; Patient Safety; Ritonavir; Severe Acute Malnutrition; Tandem Mass Spectrometry; Zidovudine

2021
Brief Report: Vaginal Viral Shedding With Undetectable Plasma HIV Viral Load in Pregnant Women Receiving 2 Different Antiretroviral Regimens: A Randomized Clinical Trial.
    Journal of acquired immune deficiency syndromes (1999), 2021, 12-01, Volume: 88, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Raltegravir Potassium; Vigna; Viral Load; Virus Shedding; Zidovudine

2021
Efficacy and safety of dolutegravir or darunavir in combination with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection (NADIA): week 96 results from a prospective, multicentre, open-label, factorial, randomised, non
    The lancet. HIV, 2022, Volume: 9, Issue:6

    Topics: Anti-HIV Agents; Darunavir; Drug Therapy, Combination; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV-1; Humans; Lamivudine; Oxazines; Piperazines; Prospective Studies; Pyridones; Ritonavir; RNA; Tenofovir; Viral Load; Zidovudine

2022
Brief Report: Impact of Antiretroviral Regimen on Pregnancy and Infant Outcomes in Women With HIV/ HBV Coinfection.
    Journal of acquired immune deficiency syndromes (1999), 2022, 09-01, Volume: 91, Issue:1

    Topics: Adult; Anti-HIV Agents; Anti-Retroviral Agents; Coinfection; Emtricitabine; Female; Hepatitis B e Antigens; HIV Infections; Humans; Infant, Newborn; Lamivudine; Pregnancy; Pregnancy Outcome; Tenofovir; Zidovudine

2022

Other Studies

1029 other study(ies) available for lamivudine and zidovudine

ArticleYear
Structure-activity relationships of beta-D-(2S,5R)- and alpha-D-(2S,5S)-1,3-oxathiolanyl nucleosides as potential anti-HIV agents.
    Journal of medicinal chemistry, 1993, Sep-03, Volume: 36, Issue:18

    Topics: Antiviral Agents; Cytosine; HIV-1; Humans; Hypoxanthines; Leukocytes, Mononuclear; Molecular Conformation; Molecular Structure; Purines; Structure-Activity Relationship; Uracil

1993
Asymmetric synthesis and biological evaluation of beta-L-(2R,5S)- and alpha-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential anti-HIV agents.
    Journal of medicinal chemistry, 1993, Jan-22, Volume: 36, Issue:2

    Topics: Antiviral Agents; Blood; Cells, Cultured; Heterocyclic Compounds; HIV-1; Humans; Magnetic Resonance Spectroscopy; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Thiophenes

1993
Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Acyclovir; Animals; Anion Transport Proteins; Antiviral Agents; Carrier Proteins; Didanosine; In Vitro Techniques; Lamivudine; Oocytes; Rats; Stavudine; Transfection; Trifluridine; Xenopus laevis; Zalcitabine; Zidovudine

2000
Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp.
    Journal of natural products, 2001, Volume: 64, Issue:11

    Topics: Animals; Antimalarials; Bromobenzenes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Dioxanes; Gas Chromatography-Mass Spectrometry; Hepatitis B; HIV; Humans; Jamaica; Lactones; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Mycobacterium tuberculosis; Neoplasms, Unknown Primary; Nuclear Magnetic Resonance, Biomolecular; Plasmodium berghei; Plasmodium falciparum; Porifera; Spectrometry, Mass, Electrospray Ionization; Tumor Cells, Cultured

2001
The protease inhibitor ritonavir inhibits the functional activity of the multidrug resistance related-protein 1 (MRP-1).
    AIDS (London, England), 2002, Sep-06, Volume: 16, Issue:13

    Topics: Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Etoposide; Flow Cytometry; HIV Protease Inhibitors; Humans; Multidrug Resistance-Associated Proteins; Probenecid; Reverse Transcriptase Inhibitors; Ritonavir; Tumor Cells, Cultured

2002
Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.
    Journal of medicinal chemistry, 2002, Oct-24, Volume: 45, Issue:22

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; Binding Sites; Cell Line; Chlorocebus aethiops; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Models, Molecular; Mutation; Purine Nucleosides; Pyrimidine Nucleosides; Quantum Theory; Stereoisomerism; Zalcitabine

2002
Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors.
    Molecular pharmacology, 2003, Volume: 63, Issue:1

    Topics: Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; CD4-Positive T-Lymphocytes; Cells, Cultured; Doxorubicin; Drug Resistance, Neoplasm; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Lamivudine; Microbial Sensitivity Tests; Neoplasm Proteins; Reverse Transcriptase Inhibitors; Zidovudine

2003
l-2',3'-Didehydro-2',3'-dideoxy-3'-fluoronucleosides: synthesis, anti-HIV activity, chemical and enzymatic stability, and mechanism of resistance.
    Journal of medicinal chemistry, 2003, Jul-17, Volume: 46, Issue:15

    Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Resistance, Viral; Drug Stability; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Lamivudine; Leukocytes, Mononuclear; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleosides; Point Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2003
Synthesis, structure-activity relationships, and mechanism of drug resistance of D- and L-beta-3'-fluoro-2',3'-unsaturated-4'-thionucleosides as anti-HIV agents.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Mutation; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Thionucleosides

2004
Synthesis, structure-activity relationships, and drug resistance of beta-d-3'-fluoro-2',3'-unsaturated nucleosides as anti-HIV Agents.
    Journal of medicinal chemistry, 2004, Jun-17, Volume: 47, Issue:13

    Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Stability; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Nucleosides; Structure-Activity Relationship

2004
(Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a new class of methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
    Journal of medicinal chemistry, 2004, Dec-30, Volume: 47, Issue:27

    Topics: Adenosine Deaminase; Antiviral Agents; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 4, Human; Nucleosides; Virus Replication

2004
Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
    Journal of medicinal chemistry, 2005, Jun-02, Volume: 48, Issue:11

    Topics: Adenine; Anti-HIV Agents; Cells, Cultured; Cyclopentanes; Dideoxynucleosides; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Lamivudine; Leukocytes, Mononuclear; Models, Molecular; Molecular Conformation; Mutation; Stereoisomerism; Structure-Activity Relationship

2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
    Journal of medicinal chemistry, 2006, Oct-05, Volume: 49, Issue:20

    Topics: Adenine; Adenosine Deaminase; Antiviral Agents; Cyclopropanes; Cytomegalovirus; Cytopathogenic Effect, Viral; Guanine; Hepatitis B virus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV-1; Humans; Purine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Viral Plaque Assay

2006
Selective inhibition of porcine endogenous retrovirus replication in human cells by acyclic nucleoside phosphonates.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Catalysis; Cell Line; Dose-Response Relationship, Drug; Endogenous Retroviruses; HIV-1; Humans; Kidney; Molecular Sequence Data; Organophosphonates; Polymerase Chain Reaction; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Stavudine; Swine; Swine, Miniature; Tenofovir; Virus Replication; Zidovudine

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Novel drug resistance pattern associated with the mutations K70G and M184V in human immunodeficiency virus type 1 reverse transcriptase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Adenine; Amino Acid Substitution; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2007
Human immunodeficiency virus types 1 and 2 exhibit comparable sensitivities to Zidovudine and other nucleoside analog inhibitors in vitro.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Anti-HIV Agents; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Zidovudine

2008
Anti-BK virus activity of nucleoside analogs.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Adenine; BK Virus; Esters; Fatty Acids; Humans; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Virus Replication

2008
Entecavir exhibits inhibitory activity against human immunodeficiency virus under conditions of reduced viral challenge.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Antiviral Agents; Cell Line; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans

2008
Periglaucines A-D, anti-HBV and -HIV-1 alkaloids from Pericampylus glaucus.
    Journal of natural products, 2008, Volume: 71, Issue:5

    Topics: Alkaloids; Anti-HIV Agents; Antiviral Agents; Crystallography, X-Ray; Drugs, Chinese Herbal; Hepatitis B virus; HIV-1; Humans; Inhibitory Concentration 50; Menispermaceae; Molecular Conformation; Molecular Structure; Plants, Medicinal

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Impact of nucleoside reverse transcriptase inhibitors on mitochondrial DNA and RNA in human skeletal muscle cells.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Cell Proliferation; Cells, Cultured; Dideoxynucleosides; DNA, Mitochondrial; Humans; Lamivudine; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Nucleosides; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Mitochondrial; Stavudine; Zidovudine

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Human immunodeficiency virus type 1 isolates with the reverse transcriptase (RT) mutation Q145M retain nucleoside and nonnucleoside RT inhibitor susceptibility.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Amino Acid Sequence; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors

2009
Genital tract, cord blood, and amniotic fluid exposures of seven antiretroviral drugs during and after pregnancy in human immunodeficiency virus type 1-infected women.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amniotic Fluid; Anti-HIV Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Fetal Blood; Genitalia, Female; HIV-1; Humans; Hydrocortisone; Pregnancy; Pregnancy Complications, Infectious; RNA, Viral

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors

2009
Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: Anti-HIV Agents; Computer Simulation; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors; Stavudine

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Adenine; Anti-HIV Agents; Cell Survival; Cells, Cultured; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Macrophages; Nucleosides; Nucleotides; Organophosphonates; Tenofovir

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Antiviral activity of seed extract from Citrus bergamia towards human retroviruses.
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Benzoxepins; Citrus; HIV Reverse Transcriptase; HIV-1; Humans; Limonins; Reverse Transcriptase Inhibitors; Seeds

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3'-azido-2',3'-dideoxypurine nucleosides.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antiviral Agents; Cell Line; Glycosylation; Hepatitis B virus; HIV-1; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Models, Molecular; Nucleosides; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Electrospray Ionization

2011
Library-based discovery and characterization of daphnane diterpenes as potent and selective HIV inhibitors in Daphne gnidium.
    Journal of natural products, 2012, Mar-23, Volume: 75, Issue:3

    Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Daphne; Diterpenes; Heterocyclic Compounds, 4 or More Rings; Mediterranean Region; Molecular Structure; Receptors, CXCR4

2012
Synthesis and anti-HIV activities of glutamate and peptide conjugates of nucleoside reverse transcriptase inhibitors.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Acetates; Anti-HIV Agents; Cell Line; Drug Resistance, Multiple, Viral; Esters; Glutamates; HIV-1; Humans; Myristic Acids; Nucleosides; Oligopeptides; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2012
Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17

    Topics: Anti-HIV Agents; Cell Line; Dicarboxylic Acids; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2012
2'-Fluoro-6'-methylene-carbocyclic adenosine phosphoramidate (FMCAP) prodrug: in vitro anti-HBV activity against the lamivudine-entecavir resistant triple mutant and its mechanism of action.
    Bioorganic & medicinal chemistry letters, 2013, Jan-15, Volume: 23, Issue:2

    Topics: Adenosine; Antiviral Agents; Binding Sites; Cells, Cultured; Drug Resistance, Viral; Guanine; Hepatitis B virus; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Lamivudine; Models, Molecular; Molecular Structure; Mutation; Prodrugs; Thermodynamics

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
    European journal of medicinal chemistry, 2013, Volume: 70

    Topics: Anti-HIV Agents; Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HeLa Cells; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Prodrugs; Structure-Activity Relationship

2013
Synthesis and biological evaluation of CHX-DAPYs as HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry, 2014, Jun-15, Volume: 22, Issue:12

    Topics: Anti-HIV Agents; Benzamides; Cell Survival; Cells, Cultured; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Nitriles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured; Virus Replication

2014
Jatrophane diterpenes as inhibitors of chikungunya virus replication: structure-activity relationship and discovery of a potent lead.
    Journal of natural products, 2014, Jun-27, Volume: 77, Issue:6

    Topics: Alphavirus Infections; Antiviral Agents; Chikungunya Fever; Chikungunya virus; Diterpenes; Euphorbia; France; HIV-1; HIV-2; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Semliki forest virus; Sindbis Virus; Structure-Activity Relationship; Virus Replication

2014
Design and synthesis of a new series of modified CH-diarylpyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2014
Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Anti-HIV Agents; Catalytic Domain; Dose-Response Relationship, Drug; Drug Design; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Molecular Structure; Niacinamide; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured

2014
Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry, 2015, Feb-01, Volume: 23, Issue:3

    Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Heterocyclic Compounds; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Nitrogen; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Sulfones

2015
Design, synthesis of new β-carboline derivatives and their selective anti-HIV-2 activity.
    Bioorganic & medicinal chemistry letters, 2015, Mar-15, Volume: 25, Issue:6

    Topics: Carbolines; Drug Design; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Piperazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Anti-HIV Agents; Chemistry Techniques, Synthetic; Computational Biology; Drug Design; HIV Reverse Transcriptase; HIV-1; Imidazoles; Molecular Docking Simulation; Protein Conformation; Pyrazines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata.
    Journal of natural products, 2015, May-22, Volume: 78, Issue:5

    Topics: Antiviral Agents; Chikungunya virus; Diterpenes; Euphorbiaceae; France; HCT116 Cells; HIV-1; HIV-2; Humans; Macrocyclic Compounds; MCF-7 Cells; Molecular Structure; Semliki forest virus; Sindbis Virus; Virus Replication

2015
Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2015, Aug-15, Volume: 25, Issue:16

    Topics: Acyclovir; Animals; Antiviral Agents; Betulinic Acid; Chlorocebus aethiops; Herpesvirus 2, Human; HIV Reverse Transcriptase; HIV-1; Humans; Pentacyclic Triterpenes; Triterpenes; Vero Cells; Virus Replication

2015
Characterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNA.
    Bioorganic & medicinal chemistry, 2016, 09-01, Volume: 24, Issue:17

    Topics: Anti-HIV Agents; Boronic Acids; HeLa Cells; HIV Core Protein p24; HIV-1; Humans; Integrase Inhibitors; Lamivudine; Nucleic Acid Conformation; Peptide Library; Peptides; Quinolones; Raltegravir Potassium; Response Elements; RNA, Viral; Structure-Activity Relationship; Virus Replication; Zidovudine

2016
Design, synthesis and anti-HIV activity of novel quinoxaline derivatives.
    European journal of medicinal chemistry, 2016, Jul-19, Volume: 117

    Topics: Animals; Anti-HIV Agents; Chlorocebus aethiops; Computer Simulation; Drug Design; HIV Integrase; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Quinoxalines; Vero Cells

2016
Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket.
    European journal of medicinal chemistry, 2016, Oct-04, Volume: 121

    Topics: Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; Molecular Docking Simulation; Protein Conformation; Pyridines; Pyrimidines; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Water

2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles.
    Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17

    Topics: Animals; Anti-HIV Agents; Cell Line, Tumor; Drug Resistance, Viral; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Molecular Docking Simulation; Mutation; Pyrimidines; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfonamides; Thiophenes

2016
Synthesis and anti-HIV activities of unsymmetrical long chain dicarboxylate esters of dinucleoside reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry letters, 2017, 05-01, Volume: 27, Issue:9

    Topics: Anti-HIV Agents; Dicarboxylic Acids; Esters; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Nucleosides; Reverse Transcriptase Inhibitors

2017
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship

2017
Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities.
    European journal of medicinal chemistry, 2020, Jan-15, Volume: 186

    Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV; HIV Reverse Transcriptase; Humans; Indazoles; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2020
Targeting dual tolerant regions of binding pocket: Discovery of novel morpholine-substituted diarylpyrimidines as potent HIV-1 NNRTIs with significantly improved water solubility.
    European journal of medicinal chemistry, 2020, Nov-15, Volume: 206

    Topics: Binding Sites; HIV Reverse Transcriptase; HIV-1; Morpholines; Mutation; Pyrimidines; Reverse Transcriptase Inhibitors; Solubility; Structure-Activity Relationship; Water

2020
Exploiting the tolerant region I of the non-nucleoside reverse transcriptase inhibitor (NNRTI) binding pocket. Part 2: Discovery of diarylpyrimidine derivatives as potent HIV-1 NNRTIs with high Fsp
    European journal of medicinal chemistry, 2021, Mar-05, Volume: 213

    Topics: Anti-HIV Agents; Binding Sites; Drug Design; HIV-1; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2021
Design of the naphthyl-diarylpyrimidines as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) via structure-based extension into the entrance channel.
    European journal of medicinal chemistry, 2021, Dec-15, Volume: 226

    Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Naphthalenes; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Antiviral Agents; Emtricitabine; HIV; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine; Zidovudine

1992
Cellular metabolism of (-) enantiomeric 2'-deoxy-3'-thiacytidine.
    Biochemical pharmacology, 1992, May-28, Volume: 43, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Blood Platelets; Cells, Cultured; Humans; Lamivudine; Lymphocytes; Pentosyltransferases; Phosphorylation; Pyrimidine Phosphorylases; Stereoisomerism; Thymidine Phosphorylase; Zalcitabine; Zidovudine

1992
Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:3

    Topics: Antiviral Agents; HIV-1; Humans; Lamivudine; Lymphocytes; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship; Zalcitabine; Zidovudine

1992
(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:4

    Topics: Cell Death; Cells, Cultured; Didanosine; Giant Cells; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; RNA-Directed DNA Polymerase; Tritium; Virus Replication; Zalcitabine; Zidovudine

1992
Biological comparison of wild-type and zidovudine-resistant isolates of human immunodeficiency virus type 1 from the same subjects: susceptibility and resistance to other drugs.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytosine; Drug Resistance, Microbial; HIV-1; Humans; Lamivudine; Nucleosides; Viral Plaque Assay; Virus Replication; Zalcitabine; Zidovudine

1991
Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:7

    Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cytosine; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Monocytes; T-Lymphocytes; Virus Replication; Zidovudine

1991
HIV-1, the brain, and combination therapy.
    Lancet (London, England), 1995, Nov-11, Volume: 346, Issue:8985

    Topics: Adult; AIDS Dementia Complex; Antiviral Agents; Child; Didanosine; Drug Combinations; HIV-1; Humans; Lamivudine; Neuroprotective Agents; Stavudine; Zalcitabine; Zidovudine

1995
A quarter-century of antiviral therapy.
    The New England journal of medicine, 1995, Dec-21, Volume: 333, Issue:25

    Topics: Antiviral Agents; Drug Therapy, Combination; Hepatitis B; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Zalcitabine; Zidovudine

1995
[AIDS therapy with reverse transcriptase inhibitors].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

1993
Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Codon; Didanosine; DNA Primers; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1994
Comparison of cord blood and peripheral blood mononuclear cells as targets for viral isolation and drug sensitivity studies involving human immunodeficiency virus type 1.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:8

    Topics: Antiviral Agents; Dose-Response Relationship, Drug; Fetal Blood; HIV Core Protein p24; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Microbial Sensitivity Tests; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

1994
Fighting all the time.
    Scientific American, 1995, Volume: 272, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Virus Replication; Zalcitabine; Zidovudine

1995
In vitro comparison of selected triple-drug combinations for suppression of HIV-1 replication: the Inter-Company Collaboration Protocol.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1995, Volume: 10 Suppl 2

    Topics: Antiviral Agents; Cell Line, Transformed; Cytopathogenic Effect, Viral; Didanosine; Drug Synergism; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nevirapine; Pyridines; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; Virus Replication; Zalcitabine; Zidovudine

1995
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine

1995
Possible involvement of cell fusion and viral recombination in generation of human immunodeficiency virus variants that display dual resistance to AZT and 3TC.
    The Journal of general virology, 1995, Volume: 76 ( Pt 10)

    Topics: Antiviral Agents; Base Sequence; Cell Fusion; Cell Line; Coculture Techniques; DNA Mutational Analysis; Drug Resistance, Multiple; Genes, pol; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; Recombination, Genetic; T-Lymphocytes; Virus Cultivation; Zalcitabine; Zidovudine

1995
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jun-15, Volume: 90, Issue:12

    Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Conserved Sequence; Deoxycytidine; Drug Resistance, Microbial; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Structure-Activity Relationship; T-Lymphocytes; Thionucleosides; Zalcitabine; Zidovudine

1993
AIDS mood upbeat--for a change.
    Science (New York, N.Y.), 1995, Feb-17, Volume: 267, Issue:5200

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Gene Products, nef; Herpesviridae; HIV; Humans; Lamivudine; nef Gene Products, Human Immunodeficiency Virus; Sarcoma, Kaposi; Simian Immunodeficiency Virus; Virus Replication; Zalcitabine; Zidovudine

1995
In vitro immunotoxicity of +/- 2'-deoxy-3'-thiacytidine, a new anti-HIV agent.
    Clinical and experimental immunology, 1993, Volume: 92, Issue:3

    Topics: Antiviral Agents; B-Lymphocytes; CD3 Complex; Cytokines; Female; HIV Infections; HIV-1; Humans; Immunoglobulins; Lamivudine; Lymphocyte Activation; Male; Phytohemagglutinins; T-Lymphocytes; Zalcitabine; Zidovudine

1993
Effect of 3'-azido-3'-deoxythymidine on human immunodeficiency virus type 1 replication in human fetal brain macrophages.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Brain; Cells, Cultured; DNA, Viral; Fetus; HIV Core Protein p24; HIV-1; Humans; Lamivudine; Macrophages; RNA, Messenger; Stereoisomerism; Time Factors; Virus Replication; Zalcitabine; Zidovudine

1993
Effects of 3'-deoxynucleoside 5'-triphosphate concentrations on chain termination by nucleoside analogs during human immunodeficiency virus type 1 reverse transcription of minus-strand strong-stop DNA.
    Journal of virology, 1996, Volume: 70, Issue:2

    Topics: Antiviral Agents; Base Sequence; Cells, Cultured; Didanosine; Dideoxynucleotides; DNA, Viral; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosides; Nucleotides; Phytohemagglutinins; RNA, Viral; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine

1996
Inhibitory effect of 3'-azido-3'-deoxythymidine on proliferative responsiveness of CD8+ lymphocytes to interleukin-2.
    Clinical and diagnostic laboratory immunology, 1994, Volume: 1, Issue:4

    Topics: Antiviral Agents; CD8-Positive T-Lymphocytes; Cell Division; Didanosine; Humans; Interleukin-2; Lamivudine; Lymphocyte Activation; Zalcitabine; Zidovudine

1994
A new HIV/AIDS drug.
    The Journal of the Arkansas Medical Society, 1996, Volume: 92, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Zalcitabine; Zidovudine

1996
Increased zidovudine prescribing associated with lamivudine availability.
    JAMA, 1996, Feb-28, Volume: 275, Issue:8

    Topics: Antiviral Agents; British Columbia; Drug Utilization; Humans; Lamivudine; Zalcitabine; Zidovudine

1996
Lamivudine as adjunct therapy in HIV.
    American family physician, 1996, Feb-01, Volume: 53, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zalcitabine; Zidovudine

1996
New nucleoside analogue, lamivudine, released for HIV therapy.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Jan-15, Volume: 53, Issue:2

    Topics: Antiviral Agents; Drug Therapy, Combination; HIV Infections; Lamivudine; Zalcitabine; Zidovudine

1996
New guidelines set for occupational HIV exposure.
    Lancet (London, England), 1996, Jul-06, Volume: 348, Issue:9019

    Topics: Accidents, Occupational; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Practice Guidelines as Topic; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
Human immunodeficiency virus type 1 kinetics in lymph nodes compared with plasma.
    The Journal of infectious diseases, 1996, Volume: 174, Issue:2

    Topics: Antiviral Agents; Biopsy; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Kinetics; Lamivudine; Lymph Nodes; RNA, Viral; Viremia; Zalcitabine; Zidovudine

1996
HIV's Achilles' heel. Drugs and education are starting to slow the AIDS virus.
    Scientific American, 1996, Volume: 275, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; Health Education; Humans; Indinavir; Lamivudine; Pyridines; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

1996
Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility.
    Journal of virology, 1996, Volume: 70, Issue:9

    Topics: Antiviral Agents; Codon; Drug Therapy, Combination; Genetic Variation; HeLa Cells; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Point Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zalcitabine; Zidovudine

1996
Interaction between lamivudine (3TC) and other nucleoside analogues for intracellular phosphorylation.
    AIDS (London, England), 1996, Volume: 10, Issue:5

    Topics: Antiviral Agents; Humans; Lamivudine; Phosphorylation; Zalcitabine; Zidovudine

1996
Kinetics of viral clearance in plasma, peripheral blood mononuclear cells and lymph nodes.
    AIDS (London, England), 1996, Volume: 10, Issue:7

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymph Nodes; Male; Plasma; RNA, Viral; Time Factors; Zidovudine

1996
New combinations of drug therapies for the treatment of the human immunodeficiency virus (HIV)
    The Journal of the American Osteopathic Association, 1996, Volume: 96, Issue:8

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Protease Inhibitors; Time Factors; Zidovudine

1996
An update on HIV/AIDS.
    Journal of the American Dental Association (1939), 1996, Volume: 127, Issue:9

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; United States; Viremia; Zidovudine

1996
Lamivudine-zidovudine treatment and clinical end points.
    JAMA, 1996, Nov-27, Volume: 276, Issue:20

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine

1996
Selection in vitro of an HIV-1 variant resistant to both lamivudine (3TC) and zidovudine.
    AIDS (London, England), 1996, Volume: 10, Issue:1

    Topics: Drug Resistance, Microbial; Genetic Variation; HIV-1; Lamivudine; Zidovudine

1996
[Lamivudine-zidovudine combination treatment].
    Deutsche medizinische Wochenschrift (1946), 1996, Oct-04, Volume: 121, Issue:40

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine

1996
Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model.
    Journal of virology, 1997, Volume: 71, Issue:1

    Topics: Drug Resistance, Microbial; Genetic Variation; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mathematical Computing; Models, Biological; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

1997
[HIV: less resistance due to combined treatment].
    Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49

    Topics: Adult; Anti-HIV Agents; Computer Graphics; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Time Factors; Zidovudine

1996
[HIV: to administer protease inhibitors early].
    Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Time Factors; Zalcitabine; Zidovudine

1996
Reverse transcriptase fidelity and HIV-1 variation.
    Science (New York, N.Y.), 1997, Jan-10, Volume: 275, Issue:5297

    Topics: Anti-HIV Agents; Cells, Cultured; Drug Resistance, Microbial; Drug Therapy, Combination; Genetic Variation; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

1997
HIV postexposure prophylaxis: new recommendations.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1997, Jan-15, Volume: 156, Issue:2

    Topics: Anti-HIV Agents; Blood-Borne Pathogens; Chemoprevention; Drug Combinations; Guidelines as Topic; Health Personnel; HIV Infections; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Diseases; Zidovudine

1997
Increased activation of the combination of 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine in the presence of hydroxyurea.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:2

    Topics: Anti-HIV Agents; Cell Line; Deoxycytosine Nucleotides; Drug Synergism; Hydroxyurea; Lamivudine; Phosphorylation; Thymine Nucleotides; Zidovudine

1997
Correspondence between the effect of zidovudine plus lamivudine on plasma HIV level/CD4 lymphocyte count and the incidence of clinical disease in infected individuals. North American Lamivudine HIV Working Group.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

1997
Focusing on the second phase of plasma HIV-1 RNA clearance.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Anti-HIV Agents; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Virus Replication; Zidovudine

1997
Saquinavir interaction with midazolam: pharmacokinetic considerations when prescribing protease inhibitors for patients with HIV disease.
    AIDS (London, England), 1997, Volume: 11, Issue:2

    Topics: Adult; Anti-HIV Agents; Cytochrome P-450 Enzyme System; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Hypnotics and Sedatives; Lamivudine; Liver; Male; Midazolam; Saquinavir; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

1997
The art of 'HAART': researchers probe the potential and limits of aggressive HIV treatments.
    JAMA, 1997, Feb-26, Volume: 277, Issue:8

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine

1997
Effect of antiretroviral combination therapy (zidovudine/didanosine or zidovudine/lamivudine) on quantitative plasma human immunodeficiency virus-ribonucleic acid in children and adolescents infected with human immunodeficiency virus.
    The Journal of pediatrics, 1997, Volume: 130, Issue:2

    Topics: Adolescent; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; RNA, Viral; Time Factors; Viral Load; Viremia; Zidovudine

1997
Human immunodeficiency virus drug therapy and virus load.
    Journal of virology, 1997, Volume: 71, Issue:4

    Topics: Anti-HIV Agents; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1997
[Antiretroviral drugs in the primary and secondary prevention of HIV infection].
    Praxis, 1997, Jan-21, Volume: 86, Issue:4

    Topics: Antiviral Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Zidovudine

1997
The maternal-fetal transfer of lamivudine in the ex vivo human placenta.
    American journal of obstetrics and gynecology, 1997, Volume: 176, Issue:2

    Topics: Anti-HIV Agents; Female; Humans; Lamivudine; Maternal-Fetal Exchange; Pregnancy; Zidovudine

1997
Investigators study morning-after AIDS treatment.
    Lancet (London, England), 1997, Mar-15, Volume: 349, Issue:9054

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Coitus; Contraceptives, Postcoital; Female; Health Knowledge, Attitudes, Practice; HIV-1; Humans; Lamivudine; Zidovudine

1997
Three-drug combination of MKC-442, lamivudine and zidovudine in vitro: potential approach towards effective chemotherapy against HIV-1.
    AIDS (London, England), 1997, Mar-15, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; Cell Line, Transformed; Cells, Cultured; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Uracil; Zidovudine

1997
In vitro screening of nucleoside analog combinations for potential use in anti-HIV therapy.
    AIDS research and human retroviruses, 1997, Apr-10, Volume: 13, Issue:6

    Topics: Anti-HIV Agents; Biotransformation; Drug Evaluation, Preclinical; Drug Interactions; Humans; Lamivudine; Phosphorylation; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1997
HIV trial stopped early after good results.
    BMJ (Clinical research ed.), 1997, Mar-08, Volume: 314, Issue:7082

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Zidovudine

1997
Treatment options for human immunodeficiency virus.
    South Dakota journal of medicine, 1996, Volume: 49, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Drug Approval; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Lamivudine; Male; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1996
Genotypic and phenotypic changes during culture of a multinucleoside-resistant human immunodeficiency virus type 1 strain in the presence and absence of additional reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12

    Topics: Antiviral Agents; Cell Line; Cells, Cultured; Didanosine; Drug Interactions; Drug Resistance, Microbial; Drug Resistance, Multiple; Genotype; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

1996
Decay characteristics of HIV-1-infected compartments during combination therapy.
    Nature, 1997, May-08, Volume: 387, Issue:6629

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; Half-Life; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Isoquinolines; Lamivudine; Leukocytes, Mononuclear; Macrophages; Mathematics; Models, Biological; Nelfinavir; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Sulfonic Acids; Viral Load; Viremia; Virus Latency; Zidovudine

1997
Response of HIV-associated thrombocytopenia to triple agent antiretroviral therapy.
    AIDS (London, England), 1997, Volume: 11, Issue:3

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Saquinavir; Thrombocytopenia; Zalcitabine; Zidovudine

1997
New drugs--reports of new drugs recently approved by the FDA. Lamivudine.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:4

    Topics: Administration, Oral; Anti-HIV Agents; Area Under Curve; Biological Availability; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

1997
Sequence and drug susceptibility of subtype C reverse transcriptase from human immunodeficiency virus type 1 seroconverters in Zimbabwe.
    Journal of virology, 1997, Volume: 71, Issue:7

    Topics: Adult; Amino Acid Sequence; Base Sequence; Didanosine; DNA, Viral; Female; Genes, env; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Nevirapine; Nucleic Acid Heteroduplexes; Phylogeny; Pyridines; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Zidovudine; Zimbabwe

1997
Quantification of HIV-1 viral load in lymphoid and blood cells: assessment during four-drug combination therapy.
    AIDS (London, England), 1997, Volume: 11, Issue:7

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymph Nodes; Male; Polymerase Chain Reaction; RNA, Viral; Saquinavir; Viral Load; Viremia; Zidovudine

1997
Increased fidelity of drug-selected M184V mutated HIV-1 reverse transcriptase as the basis for the effectiveness of 3TC in HIV clinical trials.
    Leukemia, 1997, Volume: 11 Suppl 3

    Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Microbial; Female; Genes, env; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Microbial Sensitivity Tests; Point Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1997
Cross-resistance analysis and molecular modeling of nonnucleoside reverse transcriptase inhibitors targeting drug-resistance mutations in the reverse transcriptase of human immunodeficiency virus.
    Leukemia, 1997, Volume: 11 Suppl 3

    Topics: Drug Resistance, Microbial; Genetic Variation; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Models, Molecular; Molecular Conformation; Point Mutation; Protein Conformation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine

1997
A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml.
    Nucleic acids research, 1997, Aug-01, Volume: 25, Issue:15

    Topics: Adenosine; Anti-HIV Agents; Cytidine; DNA; DNA, Viral; Drug Therapy, Combination; Guanosine; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Nelfinavir; Nucleic Acid Hybridization; RNA, Viral; Sulfonic Acids; Zidovudine

1997
Downregulation of increased CD95 (APO-1/Fas) ligand in T cells from human immunodeficiency virus-type 1-infected children after antiretroviral therapy.
    Blood, 1997, Jul-15, Volume: 90, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Therapy, Combination; Fas Ligand Protein; fas Receptor; Gene Expression Regulation; HIV Infections; HIV-1; Humans; Lamivudine; Membrane Glycoproteins; Reverse Transcriptase Inhibitors; RNA, Messenger; T-Lymphocytes; Time Factors; Transcription, Genetic; Zalcitabine; Zidovudine

1997
Lamivudine-resistant human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-resistant to zidovudine in vivo.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:2

    Topics: Amino Acid Sequence; Anti-HIV Agents; CD4 Lymphocyte Count; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; RNA, Viral; Zidovudine

1997
Cure or control of HIV/AIDS?
    Medical hypotheses, 1997, Volume: 48, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1997
Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.
    Biochemistry, 1997, Aug-19, Volume: 36, Issue:33

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Kinetics; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

1997
Central nervous system as a sanctuary for HIV-1 infection despite treatment with zidovudine, lamivudine and indinavir.
    AIDS (London, England), 1997, Volume: 11, Issue:10

    Topics: Anti-HIV Agents; Central Nervous System; Dideoxynucleosides; Drug Therapy, Combination; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine

1997
Postexposure chemoprophylaxis for occupational exposure to HIV in the dental office.
    Journal of the American Dental Association (1939), 1997, Volume: 128, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-HIV Agents; Chemoprevention; Child; Dental Auxiliaries; Dentists; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Diseases; Occupational Exposure; Practice Guidelines as Topic; Risk Factors; United States; United States Public Health Service; Universal Precautions; Zidovudine

1997
Human immunodeficiency virus type 1 dynamics in different lymphoid tissue compartments.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:3

    Topics: Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphoid Tissue; Male; RNA, Viral; Zidovudine

1997
In vitro effects of continuous pressure with zidovudine (ZDV) and lamivudine on a ZDV-resistant HIV-1 isolate.
    AIDS (London, England), 1997, Volume: 11, Issue:11

    Topics: Anti-HIV Agents; Cells, Cultured; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Core Protein p24; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Phytohemagglutinins; Tumor Cells, Cultured; Zidovudine

1997
[The management of the occupational exposures of health workers to HIV].
    Atencion primaria, 1997, Jun-15, Volume: 20, Issue:1

    Topics: Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Health Personnel; HIV Infections; HIV-1; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Exposure; Saquinavir; Zidovudine

1997
Lamivudine (3TC) phosphorylation and drug interactions in vitro.
    Biochemical pharmacology, 1997, Sep-01, Volume: 54, Issue:5

    Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Dideoxynucleosides; Drug Interactions; Humans; Kinetics; Lamivudine; Lymphocyte Activation; Lymphocytes; Mitogens; Models, Chemical; Monocytes; Phosphorylation; Stavudine; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1997
Protease inhibitor therapy in children with perinatally acquired HIV infection.
    AIDS (London, England), 1997, Volume: 11, Issue:12

    Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Protease Inhibitors; Retrospective Studies; Ritonavir; Saquinavir; Stavudine; Zidovudine

1997
The good news about AIDS.
    Indian journal of medical sciences, 1997, Volume: 51, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Humans; Lamivudine; Models, Theoretical; Protease Inhibitors; Time Factors; Zidovudine

1997
Zidovudine-resistant human immunodeficiency virus type 1 strains subcultured in the presence of both lamivudine and quinoxaline HBY 097 retain marked sensitivity to HBY 097 but not to lamivudine.
    The Journal of infectious diseases, 1997, Volume: 176, Issue:5

    Topics: Anti-HIV Agents; Antiviral Agents; Cells, Cultured; Drug Resistance; HIV-1; Humans; Lamivudine; Mutation; Quinoxalines; Reverse Transcriptase Inhibitors; Zidovudine

1997
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia.
    Science (New York, N.Y.), 1997, Nov-14, Volume: 278, Issue:5341

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Coculture Techniques; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Lymphocyte Activation; Mutation; RNA, Viral; T-Lymphocyte Subsets; Viral Load; Viremia; Virus Activation; Virus Latency; Virus Replication; Zidovudine

1997
Two-in-one tablet eases 'pill burden'.
    The American journal of nursing, 1997, Volume: 97, Issue:11

    Topics: Anti-HIV Agents; Drug Combinations; HIV Seropositivity; Humans; Lamivudine; Zidovudine

1997
[HIV-therapy: as early and as intensive as possible].
    Deutsche medizinische Wochenschrift (1946), 1997, Oct-10, Volume: 122, Issue:41

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Treatment Outcome; Zidovudine

1997
Complete regression of giant molluscum contagiosum lesions in an HIV-infected patient following combined antiretroviral therapy with saquinavir, zidovudine and lamivudine.
    AIDS (London, England), 1997, Nov-15, Volume: 11, Issue:14

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination; Humans; Lamivudine; Male; Molluscum Contagiosum; Saquinavir; Zidovudine

1997
First combination drug for patients with HIV.
    American family physician, 1997, Volume: 56, Issue:9

    Topics: Anti-HIV Agents; Drug Combinations; HIV Infections; Humans; Lamivudine; Zidovudine

1997
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 1997, Dec-12, Volume: 39, Issue:1015

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Delavirdine; Diarrhea; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Virus Replication; Zalcitabine; Zidovudine

1997
Sho-saiko-to, a traditional Kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro.
    Microbiology and immunology, 1997, Volume: 41, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; HIV Core Protein p24; HIV-1; Humans; Lamivudine; Monocytes; Virus Replication; Zidovudine

1997
Indinavir urinary stones as origin of upper urinary tract obstruction.
    Urologia internationalis, 1997, Volume: 59, Issue:4

    Topics: Aged; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Ureteral Calculi; Ureteral Obstruction; Zidovudine

1997
HIV-1 RNA detectable with ultrasensitive quantitative polymerase chain reaction in plasma but not in cerebrospinal fluid during combination treatment with zidovudine, lamivudine and indinavir.
    AIDS (London, England), 1998, Jan-01, Volume: 12, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Monitoring; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Polymerase Chain Reaction; RNA, Viral; Zidovudine

1998
Drug susceptibility of subtypes A,B,C,D, and E human immunodeficiency virus type 1 primary isolates.
    AIDS research and human retroviruses, 1998, Jan-20, Volume: 14, Issue:2

    Topics: Anti-HIV Agents; Cell Line, Transformed; Cells, Cultured; Didanosine; Foscarnet; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Zidovudine

1998
thy/liv-SCID-hu mice: a system for investigating the in vivo effects of multidrug therapy on plasma viremia and human immunodeficiency virus replication in lymphoid tissues.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:2

    Topics: Animals; Anti-HIV Agents; Chronic Disease; Drug Resistance, Microbial; Drug Therapy, Combination; Fetal Tissue Transplantation; Flow Cytometry; HIV Infections; HIV-1; Lamivudine; Leukocytes, Mononuclear; Liver Transplantation; Mice; Mice, SCID; Recurrence; Ritonavir; RNA, Viral; Saquinavir; Thymus Gland; Viremia; Zidovudine

1998
Oligonucleotide ligation assay for detecting mutations in the human immunodeficiency virus type 1 pol gene that are associated with resistance to zidovudine, didanosine, and lamivudine.
    Journal of clinical microbiology, 1998, Volume: 36, Issue:2

    Topics: Anti-HIV Agents; Codon; Didanosine; Drug Resistance, Microbial; Genes, pol; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; RNA, Viral; Sensitivity and Specificity; Sequence Analysis, DNA; Zidovudine

1998
Paediatric AIDS--is now not the right time to act?
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1997, Volume: 87, Issue:10

    Topics: Adult; Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

1997
Effect of protease inhibitors on nucleoside analogue phosphorylation in vitro.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:2

    Topics: Anti-HIV Agents; Cell Count; Cell Survival; Didanosine; Drug Interactions; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Phosphorylation; Protease Inhibitors; Ritonavir; Saquinavir; Stavudine; Trypan Blue; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1998
Neurodevelopmental/neuroradiologic recovery of a child infected with HIV after treatment with combination antiretroviral therapy using the HIV-specific protease inhibitor ritonavir.
    Pediatrics, 1998, Volume: 101, Issue:3

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Brain; CD4 Lymphocyte Count; Child; Cognition Disorders; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Magnetic Resonance Imaging; Male; Psychological Tests; Ritonavir; Virus Replication; Zidovudine

1998
Survival in 2367 zidovudine-treated patients according to use of other nucleoside analogue drugs. The EuroSIDA Study Group.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Mar-01, Volume: 17, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Dideoxynucleosides; Disease Progression; Drug Therapy, Combination; Europe; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Stavudine; Survival Analysis; Zalcitabine; Zidovudine

1998
A novel point mutation at position 156 of reverse transcriptase from feline immunodeficiency virus confers resistance to the combination of (-)-beta-2',3'-dideoxy-3'-thiacytidine and 3'-azido-3'-deoxythymidine.
    Journal of virology, 1998, Volume: 72, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cats; Cell Line; Drug Interactions; Drug Resistance, Microbial; Immunodeficiency Virus, Feline; Lamivudine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Proline; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Serine; Viral Plaque Assay; Zidovudine

1998
[Chronic HIV- and chronic HBV infection with hematuria and proteinuria].
    Deutsche medizinische Wochenschrift (1946), 1998, Feb-13, Volume: 123, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Chronic Disease; Environmental Monitoring; Erythrocyte Count; Hazardous Substances; Hematuria; Hepatitis B; HIV-1; Humans; Lamivudine; Male; Occupational Exposure; Proteinuria; Zidovudine

1998
Retention of marked sensitivity to (S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3,4-di hydroquin oxaline-2(1H)-thione (HBY 097) by an azidothymidine (AZT)-resistant human immunodeficiency virus type 1 (HIV-1) strain subcultured in the combined
    Biochemical pharmacology, 1998, Mar-01, Volume: 55, Issue:5

    Topics: Anti-HIV Agents; Antiviral Agents; Benzodiazepines; Cell Line; Delavirdine; Drug Resistance, Microbial; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Lamivudine; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mutation; Nevirapine; Quinoxalines; Recombinant Proteins; Reverse Transcriptase Inhibitors; Zidovudine

1998
Glaxo cuts HIV drug cost for developing world.
    Nature, 1998, Mar-12, Volume: 392, Issue:6672

    Topics: Anti-HIV Agents; Costs and Cost Analysis; Developing Countries; Drug Industry; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Zidovudine

1998
Profound and unanticipated anemia with lamivudine-zidovudine combination therapy in zidovudine-experienced patients with HIV infection.
    AIDS (London, England), 1998, Mar-05, Volume: 12, Issue:4

    Topics: Adult; Anemia; Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Zidovudine

1998
Regression of cytomegalovirus retinitis associated with protease-inhibitor treatment in patients with AIDS.
    American journal of ophthalmology, 1998, Volume: 125, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Saquinavir; Stavudine; Zidovudine

1998
[Hepatic steatosis during treatment with zidovudine and lamivudine in an HIV-positive patient].
    Nederlands tijdschrift voor geneeskunde, 1998, Feb-21, Volume: 142, Issue:8

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Fatty Liver; HIV Seropositivity; Humans; Lamivudine; Male; Transaminases; Zidovudine

1998
Early intervention to block HIV.
    Health news (Waltham, Mass.), 1998, Apr-20, Volume: 4, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Zidovudine

1998
Drug shows potency against HIV.
    Dentistry today, 1996, Volume: 15, Issue:5

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Zidovudine

1996
A novel polymorphism at codon 333 of human immunodeficiency virus type 1 reverse transcriptase can facilitate dual resistance to zidovudine and L-2',3'-dideoxy-3'-thiacytidine.
    Journal of virology, 1998, Volume: 72, Issue:6

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Polymorphism, Genetic; Zidovudine

1998
Changes in CD4+ and CD8+ T cell subsets in response to highly active antiretroviral therapy in HIV type 1-infected patients with prior protease inhibitor experience.
    AIDS research and human retroviruses, 1998, May-01, Volume: 14, Issue:7

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Lymphocyte Activation; Lymphocyte Count; Middle Aged; Prospective Studies; Receptors, Antigen, T-Cell, alpha-beta; RNA, Viral; T-Lymphocyte Subsets; Viral Load; Zidovudine

1998
Low blood-brain barrier permeability to azidothymidine (AZT), 3TC, and thymidine in the rat.
    Brain research, 1998, Apr-27, Volume: 791, Issue:1-2

    Topics: Animals; Anti-HIV Agents; Blood-Brain Barrier; Drug Evaluation, Preclinical; Lamivudine; Male; Rats; Rats, Sprague-Dawley; Thymidine; Zidovudine

1998
Acute HIV syndrome after discontinuation of antiretroviral therapy in a patient treated before seroconversion.
    Annals of internal medicine, 1998, May-15, Volume: 128, Issue:10

    Topics: Adult; Anti-HIV Agents; CD4-CD8 Ratio; Drug Therapy, Combination; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Male; Ritonavir; RNA, Viral; T-Lymphocytes, Cytotoxic; Zidovudine

1998
Dual resistance to zidovudine and lamivudine in patients treated with zidovudine-lamivudine combination therapy: association with therapy failure.
    The Journal of infectious diseases, 1998, Volume: 177, Issue:6

    Topics: Anti-HIV Agents; Cross-Sectional Studies; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Failure; Zidovudine

1998
Profound anemia in a newborn infant of a mother receiving antiretroviral therapy.
    The Pediatric infectious disease journal, 1998, Volume: 17, Issue:5

    Topics: Adult; Anemia; Anti-HIV Agents; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Leukocyte Count; Male; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zalcitabine; Zidovudine

1998
Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sarcoma, Kaposi; Stavudine; Treatment Outcome; Viral Load; Viremia; Zalcitabine; Zidovudine

1998
The M184V mutation in HIV-1 reverse transcriptase (RT) conferring lamivudine resistance does not result in broad cross-resistance to nucleoside analogue RT inhibitors.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Anti-HIV Agents; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Methionine; Point Mutation; Reverse Transcriptase Inhibitors; Stavudine; Valine; Zalcitabine; Zidovudine

1998
Discrepant responses to triple combination antiretroviral therapy in advanced HIV disease.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Adult; Aged; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine

1998
Persistence of HIV-1 variants harbouring the zidovudine resistance mutation at pol codon 215 in patients who respond to triple combination therapy.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Adult; Anti-HIV Agents; Codon; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Virus Latency; Zidovudine

1998
Severe anoxic hepatic necrosis in an HIV-1-hepatitis C virus-co-infected patient starting antiretroviral triple combination therapy.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination; Hepatitis C; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Necrosis; Red-Cell Aplasia, Pure; Reverse Transcriptase Inhibitors; Zidovudine

1998
Antiretroviral triple therapy decreases HIV viral load but does not alter hepatitis C virus (HCV) serum levels in HIV-HCV-co-infected haemophiliacs.
    AIDS (London, England), 1998, May-07, Volume: 12, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Hemophilia A; Hepacivirus; Hepatitis C; HIV; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zidovudine

1998
Cost-effectiveness of antiviral drug therapy to reduce mother-to-child HIV transmission in sub-Saharan Africa.
    AIDS (London, England), 1998, May-28, Volume: 12, Issue:8

    Topics: Africa South of the Sahara; Anti-HIV Agents; Breast Feeding; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Health Care Costs; HIV Infections; HIV Seroprevalence; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Zidovudine

1998
[HIV infection: DuPont Pharma presents the results of its antiretroviral agent].
    Allergie et immunologie, 1998, Volume: 30, Issue:4

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Evaluation; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viremia; Zidovudine

1998
Comparison of two antiretroviral triple combinations including the protease inhibitor indinavir in children infected with human immunodeficiency virus.
    The Pediatric infectious disease journal, 1998, Volume: 17, Issue:6

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infant; Lamivudine; Male; Reverse Transcriptase Inhibitors; Statistics, Nonparametric; Viral Load; Zidovudine

1998
Prevalence of genotypic resistance to nucleoside analogues in antiretroviral-naive and antiretroviral-experienced HIV-infected patients in Spain.
    AIDS (London, England), 1998, Jun-18, Volume: 12, Issue:9

    Topics: Adult; Anti-HIV Agents; Cross-Sectional Studies; Didanosine; Dideoxynucleosides; Drug Resistance, Microbial; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zalcitabine; Zidovudine

1998
Cost-effectiveness of chemoprophylaxis after occupational exposure to HIV.
    Archives of internal medicine, 1998, Jul-13, Volume: 158, Issue:13

    Topics: Anti-HIV Agents; Cost-Benefit Analysis; HIV Infections; Humans; Indinavir; Lamivudine; Occupational Exposure; United States; Zidovudine

1998
Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jul-21, Volume: 95, Issue:15

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Virus Integration; Virus Latency; Virus Replication; Zidovudine

1998
Prevalence of mutation associated to resistance with nucleoside analogues in a cohort of naïve HIV-1 positive subjects during the period 1984-1997.
    Journal of biological regulators and homeostatic agents, 1998, Volume: 12, Issue:1-2 Suppl

    Topics: Adult; Drug Resistance, Microbial; Female; HIV Infections; HIV Reverse Transcriptase; Humans; Lamivudine; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

1998
Therapeutic and other interventions to reduce the risk of mother-to-child transmission of HIV-1 in Europe. The European Collaborative Study.
    British journal of obstetrics and gynaecology, 1998, Volume: 105, Issue:7

    Topics: Adult; Anti-HIV Agents; Breast Feeding; Cesarean Section; Cohort Studies; Didanosine; Europe; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Prospective Studies; Risk Factors; Zidovudine

1998
Comparison of the LiPA HIV-1 RT test, selective PCR and direct solid phase sequencing for the detection of HIV-1 drug resistance mutations.
    Journal of virological methods, 1998, Volume: 73, Issue:1

    Topics: Anti-HIV Agents; Codon; Didanosine; DNA Probes; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; Zalcitabine; Zidovudine

1998
Analysis of antiretroviral nucleosides by electrospray ionization mass spectrometry and collision induced dissociation.
    Nucleosides & nucleotides, 1998, Volume: 17, Issue:5

    Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Gas Chromatography-Mass Spectrometry; Lamivudine; Models, Chemical; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Secondary Ion; Zalcitabine; Zidovudine

1998
Alternative multidrug regimen provides improved suppression of HIV-1 replication over triple therapy.
    AIDS (London, England), 1998, Jul-30, Volume: 12, Issue:11

    Topics: Adult; Anti-HIV Agents; Data Interpretation, Statistical; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Virus Replication; Zidovudine

1998
Clinical experience with adding delavirdine to combination therapy in patients in whom multiple antiretroviral treatment including protease inhibitors has failed.
    AIDS (London, England), 1998, Jul-30, Volume: 12, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Delavirdine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine

1998
Occupational exposure to blood and body fluids: new postexposure prophylaxis recommendations. United States Occupational Safety and Health Administration.
    Journal of the California Dental Association, 1998, Volume: 26, Issue:4

    Topics: Anti-HIV Agents; Blood-Borne Pathogens; Dental Staff; Dentistry; HIV Infections; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Mandatory Reporting; Occupational Exposure; Risk Factors; Risk Management; Surveys and Questionnaires; Zidovudine

1998
Chemoprophylaxis after occupational exposure to human immunodeficiency virus in forensic autopsy.
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1998, Volume: 52, Issue:2

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Forensic Medicine; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Occupational Exposure; Zidovudine

1998
Neurological efficacy of stavudine, zidovudine, and lamivudine.
    Lancet (London, England), 1998, Aug-01, Volume: 352, Issue:9125

    Topics: AIDS Dementia Complex; Anti-HIV Agents; beta 2-Microglobulin; Blood-Brain Barrier; Brain; HIV-1; Humans; Lamivudine; Meninges; RNA, Viral; Stavudine; Virus Shedding; Zidovudine

1998
Neurological efficacy of stavudine, zidovudine, and lamivudine.
    Lancet (London, England), 1998, Aug-01, Volume: 352, Issue:9125

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Brain; Female; Follow-Up Studies; HIV-1; Humans; Indinavir; Lamivudine; Neopterin; RNA, Viral; Stavudine; Viral Load; Virus Replication; Zidovudine

1998
Cerebrospinal fluid levels of antiretroviral medications: abstract and commentary.
    JAMA, 1998, Sep-09, Volume: 280, Issue:10

    Topics: Anti-HIV Agents; Blood-Brain Barrier; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Zidovudine

1998
Clozapine treatment of HIV-associated psychosis--too much bone marrow toxicity?
    Pharmacopsychiatry, 1998, Volume: 31, Issue:4

    Topics: Adult; Anti-HIV Agents; Antipsychotic Agents; Clozapine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Neutropenia; Psychotic Disorders; Zidovudine

1998
Development of a new cartridge radioimmunoassay for determination of intracellular levels of lamivudine triphosphate in the peripheral blood mononuclear cells of human immunodeficiency virus-infected patients.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:10

    Topics: Animals; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Rabbits; Radioimmunoassay; Zidovudine

1998
Taste and smell complaints in HIV-infected patients.
    AIDS (London, England), 1998, Sep-10, Volume: 12, Issue:13

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Clarithromycin; Didanosine; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Quality of Life; Ritonavir; Smell; Surveys and Questionnaires; Taste; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

1998
Progressive multifocal leukoencephalopathy following initiation of highly active antiretroviral therapy.
    AIDS (London, England), 1998, Sep-10, Volume: 12, Issue:13

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Seropositivity; Humans; Indinavir; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Male; Viral Load; Zidovudine

1998
[Weak antiviral effect of changing two nucleoside analogues combined with antiretroviral agents. 3TC and d4T after ZDU and ddi or ddc].
    Presse medicale (Paris, France : 1983), 1998, Feb-28, Volume: 27, Issue:8

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine

1998
Effect of antiretroviral therapy and viral load on the perceived risk of HIV transmission and the need for safer sexual practices.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Oct-01, Volume: 19, Issue:2

    Topics: Anti-HIV Agents; Attitude to Health; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Lamivudine; Male; Protease Inhibitors; Reverse Transcriptase Inhibitors; Risk Factors; Sexual Behavior; Sexual Partners; Sexually Transmitted Diseases, Viral; Surveys and Questionnaires; Viral Load; Zidovudine

1998
Cost of preventing HIV infection after sexual exposure.
    The Journal of family practice, 1998, Volume: 47, Issue:4

    Topics: Anti-HIV Agents; Cost-Benefit Analysis; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Models, Theoretical; Reproducibility of Results; Sexual Behavior; Zidovudine

1998
Precipitous declines in hemoglobin levels associated with combination zidovudine and lamivudine therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:4

    Topics: Adult; Anemia; Anti-HIV Agents; Drug Therapy, Combination; Female; Hemoglobins; HIV Infections; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zidovudine

1998
Acute generalized exanthematous pustulosis: a cutaneous adverse effect due to prophylactic antiviral therapy with protease inhibitor.
    Archives of internal medicine, 1998, Oct-26, Volume: 158, Issue:19

    Topics: Acute Disease; Adult; Anti-HIV Agents; Diagnosis, Differential; Drug Eruptions; Exanthema; HIV Infections; Humans; Lamivudine; Male; Protease Inhibitors; Skin Diseases, Vesiculobullous; Zidovudine

1998
Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:4

    Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Atrophy; Brain; Female; Humans; Ibuprofen; Indinavir; Lamivudine; Magnetic Resonance Imaging; Neurons; Neurotoxins; Nitric Oxide; Quinolinic Acid; Toxicity Tests; Tumor Necrosis Factor-alpha; Zidovudine

1998
Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study.
    AIDS (London, England), 1998, Nov-12, Volume: 12, Issue:16

    Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation; Biomarkers; Female; HIV Infections; HLA-DR Antigens; Humans; Lamivudine; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Count; Male; Membrane Glycoproteins; NAD+ Nucleosidase; Prospective Studies; Ritonavir; RNA, Viral; T-Lymphocytes; Viral Load; Zidovudine

1998
Phase III results of second-generation HIV protease inhibitor reported.
    Oncology (Williston Park, N.Y.), 1998, Volume: 12, Issue:11

    Topics: Anti-HIV Agents; Carbamates; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Sulfonamides; Viral Load; Zidovudine

1998
Decay of HIV-1 DNA in patients receiving suppressive antiretroviral therapy.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Dec-15, Volume: 19, Issue:5

    Topics: Adult; Amino Acid Sequence; Anti-HIV Agents; Base Sequence; CD4 Lymphocyte Count; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, pol; Genotype; Half-Life; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Longitudinal Studies; Male; Molecular Sequence Data; Mutation; Retrospective Studies; RNA, Viral; Zidovudine

1998
HIV-1 peripheral neuropathy and combination antiretroviral therapy.
    Lancet (London, England), 1998, Dec-12, Volume: 352, Issue:9144

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nelfinavir; Nevirapine; Peripheral Nervous System Diseases; Saquinavir; Zidovudine

1998
Report updates recommendations for health workers exposed to HIV.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Sep-01, Volume: 55, Issue:17

    Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Health Personnel; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Occupational Exposure; Practice Guidelines as Topic; United States; United States Public Health Service; Zidovudine

1998
Immunologic and virologic response of HIV-2 infection to antiretroviral therapy.
    AIDS (London, England), 1998, Dec-24, Volume: 12, Issue:18

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-2; Humans; Indinavir; Lamivudine; Male; Proviruses; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1998
[Clinical case of the month. Apropos of pancytopenia in a seropositive patient].
    Revue medicale de Liege, 1998, Volume: 53, Issue:12

    Topics: Adult; Anemia, Aplastic; Anti-HIV Agents; Bone Marrow; HIV Infections; HIV Seropositivity; HIV-1; Humans; Indinavir; Lamivudine; Male; Pancytopenia; Stavudine; Zidovudine

1998
Persistent parvovirus B19 related anemia of seven years' duration in an HIV-infected patient: complete remission associated with highly active antiretroviral therapy.
    American journal of hematology, 1999, Volume: 60, Issue:2

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Erythrocyte Transfusion; HIV Infections; Humans; Immunoglobulins, Intravenous; Lamivudine; Male; Parvoviridae Infections; Parvovirus B19, Human; Red-Cell Aplasia, Pure; Remission Induction; Ritonavir; Saquinavir; Zidovudine

1999
Genotypic and phenotypic resistance under zidovudine and lamivudine therapy in human immunodeficiency virus-infected children.
    European journal of pediatrics, 1999, Volume: 158, Issue:1

    Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Resistance; Female; Genotype; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Phenotype; Zidovudine

1999
Inhibition of human immunodeficiency virus type 1 replication by combination of transcription inhibitor K-12 and other antiretroviral agents in acutely and chronically infected cells.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3

    Topics: Alkaloids; Anti-HIV Agents; Anti-Infective Agents; Benzylisoquinolines; Cell Line; Drug Synergism; Fluoroquinolones; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Nelfinavir; Nevirapine; NF-kappa B; Piperazines; Reverse Transcriptase Inhibitors; Tumor Necrosis Factor-alpha; Virus Replication; Zidovudine

1999
Cheap treatment cuts HIV transmission.
    Science (New York, N.Y.), 1999, Feb-12, Volume: 283, Issue:5404

    Topics: Africa; Anti-HIV Agents; Controlled Clinical Trials as Topic; Drug Therapy, Combination; Ethics, Medical; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Labor, Obstetric; Lamivudine; Placebos; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

1999
Antiretroviral drugs: new agents, new combinations line up against HIV.
    Hospital technology series, 1996, Volume: 15, Issue:1

    Topics: Antiviral Agents; Australia; Didanosine; Drug Therapy, Combination; Europe; HIV; HIV Infections; Humans; Lamivudine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine

1996
PHS recommends preventive drugs for HIV exposures.
    OR manager, 1996, Volume: 12, Issue:8

    Topics: Antiviral Agents; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Pyridines; United States; United States Public Health Service; Virus Replication; Zalcitabine; Zidovudine

1996
I have learned to hope.
    Newsweek, 1996, Dec-02, Volume: 128, Issue:23

    Topics: Acquired Immunodeficiency Syndrome; Attitude to Death; Attitude to Health; Boston; Fear; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Radio; Reverse Transcriptase Inhibitors; Survivors; Zidovudine

1996
Modelling the cost effectiveness of lamivudine/zidovudine combination therapy in HIV infection.
    PharmacoEconomics, 1997, Volume: 12, Issue:1

    Topics: Adult; Cost-Benefit Analysis; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Models, Economic; Zidovudine

1997
AIDS: the new drug war.
    Fortune, 1998, Apr-27, Volume: 137, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Black or African American; Dideoxynucleosides; Drug Combinations; Drug Industry; Humans; Investments; Lamivudine; Stavudine; United States; Zidovudine

1998
The cost-effectiveness of treatment with lamivudine and zidovudine compared with zidovudine alone: a comparison of Markov model and trial data estimates.
    The American journal of managed care, 1998, Volume: 4, Issue:7

    Topics: Cost-Benefit Analysis; Drug Therapy, Combination; Health Care Costs; HIV Infections; Humans; Lamivudine; Markov Chains; Models, Econometric; Reverse Transcriptase Inhibitors; United States; Zidovudine

1998
Early lipodystrophy occurring during post-exposure prophylaxis.
    Sexually transmitted infections, 1998, Volume: 74, Issue:6

    Topics: Adult; Anti-HIV Agents; HIV Infections; Homosexuality, Male; Humans; Lamivudine; Lipodystrophy; Male; Rape; Zidovudine

1998
Persistent alterations in T-cell repertoire, cytokine and chemokine receptor gene expression after 1 year of highly active antiretroviral therapy.
    AIDS (London, England), 1999, Feb-04, Volume: 13, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytokines; Female; Gene Expression; HIV Infections; HIV Protease Inhibitors; Humans; Interferon-gamma; Interleukin-10; Interleukin-13; Interleukin-2; Interleukin-4; Lamivudine; Longitudinal Studies; Male; Receptors, CCR3; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Interleukin; Receptors, Interleukin-12; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Messenger; Saquinavir; Zidovudine

1999
Combination antiretroviral therapy including ritonavir in children infected with human immunodeficiency.
    AIDS (London, England), 1999, Jan-14, Volume: 13, Issue:1

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Zidovudine

1999
Highly active antiretroviral therapy used to treat concurrent hepatitis B and human immunodeficiency virus infections.
    Journal of gastroenterology, 1999, Volume: 34, Issue:2

    Topics: Adult; Anti-HIV Agents; Biopsy, Needle; Drug Therapy, Combination; Gene Products, pol; Hepatitis B Antibodies; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Liver; Male; Zidovudine

1999
[AZT and 3TC treatment in a pregnant woman with HIV infection].
    Medicina clinica, 1999, Mar-13, Volume: 112, Issue:9

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

1999
Modeling the long-term outcomes and costs of HIV antiretroviral therapy using HIV RNA levels: application to a clinical trial.
    AIDS research and human retroviruses, 1999, Apr-10, Volume: 15, Issue:6

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Cost-Benefit Analysis; Costs and Cost Analysis; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Models, Biological; Models, Economic; Outcome and Process Assessment, Health Care; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Zidovudine

1999
[Infectious diseases in 1998].
    La Revue de medecine interne, 1999, Volume: 20, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-HIV Agents; Antiviral Agents; Bacterial Vaccines; Blood Donors; Clinical Trials as Topic; Drug Therapy, Combination; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Interferons; Lamivudine; Middle Aged; Multicenter Studies as Topic; Pneumonia, Pneumococcal; Randomized Controlled Trials as Topic; Ribavirin; Streptococcus pneumoniae; Transfusion Reaction; Zidovudine

1999
Salvage therapy with ritonavir-saquinavir plus two nucleoside reverse transcriptase inhibitors in patients failing with amprenavir-zidovudine-lamivudine.
    AIDS (London, England), 1999, May-07, Volume: 13, Issue:7

    Topics: Adult; Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; Salvage Therapy; Saquinavir; Sulfonamides; Zidovudine

1999
Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro.
    AIDS research and human retroviruses, 1999, Jun-10, Volume: 15, Issue:9

    Topics: Anti-HIV Agents; Deoxyadenine Nucleotides; Didanosine; Dideoxynucleotides; Drug Interactions; Guanosine; Humans; Hydroxyurea; Inosine; Intracellular Fluid; Lamivudine; Pentoxifylline; Stavudine; U937 Cells; Zidovudine

1999
Utilization of transgenic mice replicating high levels of hepatitis B virus for antiviral evaluation of lamivudine.
    Antiviral research, 1999, Volume: 42, Issue:2

    Topics: Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis, Viral, Animal; Humans; Lamivudine; Male; Mice; Mice, Transgenic; Time Factors; Treatment Outcome; Virus Replication; Zidovudine

1999
Needle-stick injuries and HIV infection: a surgeon's personal experience and review of postexposure prophylaxis. St. Paul's Ocular AIDS Group.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1999, Volume: 34, Issue:4

    Topics: Anti-HIV Agents; Dacryocystorhinostomy; Drug Therapy, Combination; HIV Infections; HIV Seropositivity; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Middle Aged; Needlestick Injuries; Occupational Exposure; Ophthalmology; Primary Prevention; Risk Factors; Zidovudine

1999
Complete regression of AIDS-related Kaposi's sarcoma in a child treated with highly active antiretroviral therapy.
    AIDS (London, England), 1999, Jun-18, Volume: 13, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Child, Preschool; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Sarcoma, Kaposi; Treatment Outcome; Zidovudine

1999
Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy.
    Journal of virology, 1999, Volume: 73, Issue:8

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytotoxicity, Immunologic; Drug Therapy, Combination; Epitopes, T-Lymphocyte; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Longitudinal Studies; Reverse Transcriptase Inhibitors; Stavudine; T-Lymphocytes, Cytotoxic; Viral Load; Viremia; Zidovudine

1999
Multiple drug resistance genotype causing failure of antiretroviral treatment in an HIV-infected patient heavily exposed to nucleoside analogues.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1999, Volume: 18, Issue:5

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Resistance, Multiple; Drug Therapy, Combination; Genes, MDR; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nucleosides; Point Mutation; Zidovudine

1999
Development and significance of the HIV-1 reverse transcriptase M184V mutation during combination therapy with lamivudine, zidovudine, and protease inhibitors.
    Journal of acquired immune deficiency syndromes (1999), 1999, Jul-01, Volume: 21, Issue:3

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Methionine; Point Mutation; Retrospective Studies; Reverse Transcriptase Inhibitors; Valine; Zidovudine

1999
Antiviral effect of AZT versus stavudine in combination with lamivudine and indinavir in the context of a populational study.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21, Issue:4

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Stavudine; Viremia; Zidovudine

1999
Phenotypic changes in drug susceptibility associated with failure of human immunodeficiency virus type 1 (HIV-1) triple combination therapy.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Nelfinavir; Phenotype; Salvage Therapy; Time Factors; Transfection; Treatment Failure; Zidovudine

1999
IAS position paper on prevention of HIV 1 mother-to-child transmission. International Aids Society.
    AIDS (London, England), 1999, Jul-30, Volume: 13, Issue:11

    Topics: Anti-HIV Agents; Child, Preschool; Developing Countries; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Program Development; Reverse Transcriptase Inhibitors; Societies, Medical; Zidovudine

1999
Quality of life in asymptomatic patients with early HIV infection initiating antiretroviral therapy. Swiss HIV Cohort Study.
    AIDS (London, England), 1999, Aug-20, Volume: 13, Issue:12

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Quality of Life; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Ritonavir; Sickness Impact Profile; Zidovudine

1999
The use of human immunodeficiency virus postexposure prophylaxis after successful artificial insemination.
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:3

    Topics: Adult; Antiviral Agents; Female; HIV Infections; HIV Seropositivity; Humans; Indinavir; Insemination, Artificial, Heterologous; Lamivudine; Male; Pregnancy; Tissue Donors; Zidovudine

1999
Rapid development of genotypic resistance to lamivudine when combined with zidovudine in pregnancy.
    Journal of medical virology, 1999, Volume: 59, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA-Directed DNA Polymerase; Viral Load; Zidovudine

1999
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues.
    Lancet (London, England), 1999, Sep-25, Volume: 354, Issue:9184

    Topics: Acidosis, Lactic; Anti-HIV Agents; Child, Preschool; DNA, Mitochondrial; Female; France; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Maternal-Fetal Exchange; Mitochondrial Encephalomyopathies; Pregnancy; Prenatal Exposure Delayed Effects; Reference Values; Retrospective Studies; Zidovudine

1999
Predictors of optimal virological response to potent antiretroviral therapy.
    AIDS (London, England), 1999, Oct-01, Volume: 13, Issue:14

    Topics: Adult; Anti-HIV Agents; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV Seropositivity; Humans; Lamivudine; Male; Nelfinavir; Outcome Assessment, Health Care; Predictive Value of Tests; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load; Zidovudine

1999
Pharmacokinetics of nelfinavir in an HIV patient with renal insufficiency.
    AIDS (London, England), 1999, Oct-01, Volume: 13, Issue:14

    Topics: Anti-HIV Agents; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Renal Insufficiency; Reverse Transcriptase Inhibitors; Zidovudine

1999
Nucleoside analogues achieve high concentrations in seminal plasma: relationship between drug concentration and virus burden.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:6

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; RNA, Viral; Semen; Viral Load; Zidovudine

1999
[Pustulous psoriasis resistant to conventional treatment].
    Enfermedades infecciosas y microbiologia clinica, 1999, Volume: 17, Issue:8

    Topics: Adult; Antiviral Agents; Drug Resistance; Drug Therapy, Combination; HIV Seropositivity; Humans; Lamivudine; Male; Psoriasis; Saquinavir; Zidovudine

1999
Severe anemia as a newly recognized side-effect caused by lamivudine.
    AIDS (London, England), 1999, Nov-12, Volume: 13, Issue:16

    Topics: Anemia; Anti-HIV Agents; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Zidovudine

1999
Saquinavir hard gel suppresses viral load insufficiently in HIV-infected patients naive to anti-retroviral therapy: a retrospective cohort study.
    Scandinavian journal of infectious diseases, 1999, Volume: 31, Issue:5

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Controlled Clinical Trials as Topic; Denmark; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Multicenter Studies as Topic; Retrospective Studies; Ritonavir; RNA, Viral; Saquinavir; Viral Load; Zidovudine

1999
Highly active anti-retroviral therapy (HAART) is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients.
    Clinical and experimental immunology, 1999, Volume: 118, Issue:3

    Topics: Adult; Aged; Anti-HIV Agents; Apoptosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Stavudine; Viral Load; Zalcitabine; Zidovudine

1999
Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection.
    AIDS (London, England), 1999, Dec-03, Volume: 13, Issue:17

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Adult; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; HIV Infections; HIV-1; HLA-DR Antigens; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Male; Membrane Glycoproteins; NAD+ Nucleosidase; Palatine Tonsil; Proviruses; T-Lymphocyte Subsets; Time Factors; Viremia; Virus Replication; Zidovudine

1999
Advanced Hodgkin's disease in a pregnant HIV seropositive woman: favorable mother and baby outcome following combined anticancer and antiretroviral therapy.
    American journal of hematology, 2000, Volume: 63, Issue:1

    Topics: Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Female; HIV Seropositivity; Hodgkin Disease; Humans; Lamivudine; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Remission Induction; Stavudine; Zidovudine

2000
Incidence and predictors of virologic failure of antiretroviral triple-drug therapy in a community-based cohort.
    AIDS research and human retroviruses, 1999, Dec-10, Volume: 15, Issue:18

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Disease Progression; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Ritonavir; RNA, Viral; Salvage Therapy; Saquinavir; Stavudine; Switzerland; Treatment Failure; Viral Load; Zalcitabine; Zidovudine

1999
Effect of combination antiretroviral therapy on T-cell immunity in acute human immunodeficiency virus type 1 infection.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:1

    Topics: Acute Disease; Adult; Anti-HIV Agents; Candida; CD4 Lymphocyte Count; Chronic Disease; Cytokines; Cytotoxicity, Immunologic; Drug Therapy, Combination; Female; HIV Antigens; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Male; Middle Aged; Prospective Studies; T-Lymphocytes; Tetanus Toxoid; Viral Load; Zidovudine

2000
Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, lamivudine, and ritonavir therapy.
    The Journal of infectious diseases, 2000, Volume: 181, Issue:1

    Topics: Adult; Aged; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocytes; Male; Middle Aged; Ritonavir; T-Lymphocyte Subsets; Thymus Gland; Tomography; Zidovudine

2000
Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site.
    The Journal of biological chemistry, 2000, Jan-07, Volume: 275, Issue:1

    Topics: Catalytic Domain; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Proline; Reverse Transcriptase Inhibitors; Thionucleosides; Thiophenes; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine

2000
Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens.
    JAMA, 2000, Jan-12, Volume: 283, Issue:2

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Phenotype; RNA, Viral; Treatment Failure; Viral Load; Zidovudine

2000
Hydroxyurea interferes with antigen-dependent T-cell activation in vitro.
    European journal of clinical investigation, 2000, Volume: 30, Issue:2

    Topics: Candida albicans; HIV-1; Humans; Hydroxyurea; Lamivudine; Lymphocyte Activation; Phytohemagglutinins; Reverse Transcriptase Inhibitors; T-Lymphocytes; Zidovudine

2000
Effortless unintentional smoking cessation after lamivudine-zidovudine-indinavir post-exposure anti-HIV chemoprophylaxis.
    Addiction (Abingdon, England), 1999, Volume: 94, Issue:1

    Topics: Adult; Anti-HIV Agents; HIV Infections; Humans; Indinavir; Lamivudine; Male; Smoking; Smoking Cessation; Zidovudine

1999
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
    Neurology, 2000, Jan-25, Volume: 54, Issue:2

    Topics: AIDS Dementia Complex; Animals; Cells, Cultured; Didanosine; Dideoxynucleosides; Disease Models, Animal; HIV-1; Humans; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Reverse Transcriptase Inhibitors; Stavudine; Virus Replication; Zidovudine

2000
A novel human immunodeficiency virus type 1 reverse transcriptase mutational pattern confers phenotypic lamivudine resistance in the absence of mutation 184V.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3

    Topics: Anti-HIV Agents; Drug Resistance, Microbial; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutagenesis, Site-Directed; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Zidovudine

2000
Induction and maintenance treatment regimens for HIV-1 infection in vitro.
    Antiviral therapy, 1999, Volume: 4, Issue:1

    Topics: Anti-HIV Agents; Cell Line; DNA, Viral; HIV-1; Humans; Indinavir; Lamivudine; Zidovudine

1999
Presence of genotypic resistance in nucleoside analogue-treated HIV-1-infected patients with undetectable viral load.
    Antiviral therapy, 1999, Volume: 4, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance; Genes, pol; Genotype; HIV-1; Humans; Lamivudine; Point Mutation; RNA, Viral; Zalcitabine; Zidovudine

1999
Loss of lamivudine resistance in a zidovudine and lamivudine dual-resistant HIV-1 isolate after discontinuation of in vitro lamivudine drug pressure.
    Antiviral therapy, 1998, Volume: 3, Issue:4

    Topics: Anti-HIV Agents; Codon; Drug Resistance; Genotype; HIV-1; Humans; Lamivudine; Phenotype; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Virus Replication; Zidovudine

1998
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 2000, Jan-10, Volume: 42, Issue:1069

    Topics: Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Costs; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine; Zidovudine

2000
Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor beta chain repertoire and reduces the level of T-cell oligoclonality.
    Blood, 2000, Mar-01, Volume: 95, Issue:5

    Topics: Acute Disease; Anti-HIV Agents; Clone Cells; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Saquinavir; T-Lymphocytes, Cytotoxic; Viremia; Zidovudine

2000
A model of HIV-1 pathogenesis that includes an intracellular delay.
    Mathematical biosciences, 2000, Volume: 163, Issue:2

    Topics: Anti-HIV Agents; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Biological; Numerical Analysis, Computer-Assisted; Reverse Transcriptase Inhibitors; Zidovudine

2000
Tolerability and side-effects of post-exposure prophylaxis for HIV infection.
    Lancet (London, England), 2000, Feb-26, Volume: 355, Issue:9205

    Topics: Anti-HIV Agents; Drug Combinations; Drug Tolerance; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; London; Needlestick Injuries; Patient Compliance; Personnel, Hospital; Retrospective Studies; Zidovudine

2000
Emergence of dual resistance to zidovudine and lamivudine in HIV-1-infected patients treated with zidovudine plus lamivudine as initial therapy.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jan-01, Volume: 23, Issue:1

    Topics: Amino Acid Sequence; Anti-HIV Agents; Codon; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Zidovudine

2000
Normalization of CD4+ cell numbers and reduced levels of memory CD8+ cells in blood and tonsillar tissue after highly active antiretroviral therapy in early HIV type-1 infection.
    AIDS research and human retroviruses, 2000, Feb-10, Volume: 16, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Immunologic Memory; Indinavir; Lamivudine; Male; Palatine Tonsil; Reverse Transcriptase Inhibitors; T-Lymphocyte Subsets; Time Factors; Viremia; Zidovudine

2000
Early immune reconstitution after potent antiretroviral therapy in HIV-infected children correlates with the increase in thymus volume.
    AIDS (London, England), 2000, Feb-18, Volume: 14, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Cohort Studies; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Organ Size; Reverse Transcriptase Inhibitors; Stavudine; Thymus Gland; Viral Load; Zidovudine

2000
The triple combination indinavir-zidovudine-lamivudine is highly synergistic.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:4

    Topics: Anti-HIV Agents; Cells, Cultured; Coloring Agents; Drug Synergism; HIV-1; Humans; Indinavir; Lamivudine; Tetrazolium Salts; Zidovudine

2000
[First HIV triple therapy with one tablet].
    Deutsche medizinische Wochenschrift (1946), 2000, Feb-25, Volume: 125, Issue:8

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tablets; Zidovudine

2000
Predicting the duration of antiviral treatment needed to suppress plasma HIV-1 RNA.
    The Journal of clinical investigation, 2000, Volume: 105, Issue:6

    Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cohort Studies; Dideoxynucleosides; Furans; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lymph Nodes; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Sulfonamides; Time Factors; Viral Load; Viremia; Zidovudine

2000
The M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1 impairs rescue of chain-terminated DNA synthesis.
    Journal of virology, 2000, Volume: 74, Issue:8

    Topics: Adenosine Triphosphate; Anti-HIV Agents; Base Sequence; Diphosphates; DNA, Viral; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Templates, Genetic; Zidovudine

2000
Mitigation of hepato-cellular injury caused by HAART with glycyrrhizin compound in patients co-infected with HIV and HCV.
    Japanese journal of infectious diseases, 1999, Volume: 52, Issue:6

    Topics: Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Combinations; Drug Therapy, Combination; Glycine; Glycyrrhetinic Acid; Hemophilia A; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zalcitabine; Zidovudine

1999
[A two-year follow-up of zidovudine plus lamivudine combined with indinavir in antivival naive HIV-infected patients].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2000, Volume: 74, Issue:2

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine

2000
Amprenavir study results released.
    AIDS patient care and STDs, 1999, Volume: 13, Issue:12

    Topics: Anti-HIV Agents; Carbamates; Clinical Trials, Phase III as Topic; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Sulfonamides; Viral Load; Zidovudine

1999
Anti-human immunodeficiency virus type 1 (HIV-1) CD8(+) T-lymphocyte reactivity during combination antiretroviral therapy in HIV-1-infected patients with advanced immunodeficiency.
    Journal of virology, 2000, Volume: 74, Issue:9

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cell Lineage; Drug Therapy, Combination; Gene Products, gag; Gene Products, pol; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Interferon-gamma; Lamivudine; Longitudinal Studies; Lymphocyte Activation; Peptides; Phenotype; Phosphoproteins; Reverse Transcriptase Inhibitors; T-Lymphocytes, Cytotoxic; Viral Load; Viral Matrix Proteins; Zidovudine

2000
The efficacy and tolerability of combination antiretroviral therapy in pregnancy: infant and maternal outcome.
    International journal of STD & AIDS, 2000, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Treatment Outcome; Zidovudine

2000
Immune repopulation after HAART in previously untreated HIV-1-infected children. Paediatric European Network for Treatment of AIDS (PENTA) Steering Committee.
    Lancet (London, England), 2000, Apr-15, Volume: 355, Issue:9212

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Dideoxynucleosides; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Immunologic Memory; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nelfinavir; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine

2000
Baseline HIV type 1 genotypic resistance to a newly added nucleoside analog is predictive of virologic failure of the new therapy.
    AIDS research and human retroviruses, 2000, Apr-10, Volume: 16, Issue:6

    Topics: CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Polymerase Chain Reaction; Predictive Value of Tests; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zalcitabine; Zidovudine

2000
Efavirenz in HIV infection.
    The New England journal of medicine, 2000, Apr-27, Volume: 342, Issue:17

    Topics: Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Oxazines; Research Design; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2000
Highly active antiretroviral therapy inhibits cytokine production in HIV-uninfected subjects.
    AIDS (London, England), 2000, Apr-14, Volume: 14, Issue:6

    Topics: Adult; Anti-HIV Agents; Child; Cytokines; Drug Therapy, Combination; HIV Infections; HIV Seronegativity; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine

2000
[A case of HIV encephalopathy with dementia which showed significant improvement after the combination antiretroviral therapy].
    Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:2

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Treatment Outcome; Zidovudine

2000
HE2000 shows efficacy.
    AIDS patient care and STDs, 1999, Volume: 13, Issue:6

    Topics: Animals; Anti-HIV Agents; Disease Models, Animal; Drugs, Investigational; Haplorhini; Lamivudine; Ritonavir; Simian Acquired Immunodeficiency Syndrome; Survival Analysis; Viral Load; Zidovudine

1999
Cutaneous side effects induced by indinavir.
    European journal of dermatology : EJD, 2000, Volume: 10, Issue:4

    Topics: Adult; Alopecia; Didanosine; Drug Eruptions; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Middle Aged; Pruritus; Pyoderma Gangrenosum; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Scalp Dermatoses; Skin; Stavudine; Zalcitabine; Zidovudine

2000
Zidovudine + lamivudine: new preparation. Fewer tablets required.
    Prescrire international, 1999, Volume: 8, Issue:40

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine

1999
Simultaneous determination of zidovudine and lamivudine in human serum using HPLC with tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2000, Volume: 22, Issue:6

    Topics: Anti-HIV Agents; Antibody Specificity; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Isotope Labeling; Lamivudine; Mass Spectrometry; Radioimmunoassay; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Zidovudine

2000
Prevalence of primary resistance to zidovudine and lamivudine in drug-naive human immunodeficiency virus type-1 infected patients: high proportion of reverse transcriptase codon 215 mutant in circulating lymphocytes and free virus.
    Journal of medical virology, 2000, Volume: 61, Issue:3

    Topics: Anti-HIV Agents; Codon; DNA, Viral; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lymphocytes; Nucleic Acid Hybridization; Polymerase Chain Reaction; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2000
Failure to develop HIV infection after receipt of HIV-contaminated blood and postexposure prophylaxis.
    Annals of internal medicine, 2000, Jul-04, Volume: 133, Issue:1

    Topics: Adolescent; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Transfusion Reaction; Zidovudine

2000
Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, May-26, Volume: 742, Issue:1

    Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Mass Spectrometry; Reference Standards; Reverse Transcriptase Inhibitors; Semen; Zidovudine

2000
Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir.
    AIDS (London, England), 2000, Jun-16, Volume: 14, Issue:9

    Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Disease Reservoirs; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Semen; Stavudine; Viral Load; Zidovudine

2000
Onset of HIV-1 antibody production after highly active antiretroviral therapy in a seronegative HIV-1-infected child.
    AIDS (London, England), 2000, Jun-16, Volume: 14, Issue:9

    Topics: Anti-HIV Agents; Antibody Formation; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Antibodies; HIV Infections; HIV Seronegativity; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Viremia; Zidovudine

2000
[Human immunodeficiency virus: current pregnancy aspects].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2000, Volume: 7 Suppl 2

    Topics: Anti-HIV Agents; Cesarean Section; Drug Therapy, Combination; Female; HIV Infections; HIV-1; HIV-2; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2000
[Antiretroviral drugs and pregnancy: apropos of an alert regarding mitochondrial pathology and nucleoside analogs].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2000, Volume: 7 Suppl 2

    Topics: Abnormalities, Drug-Induced; Animals; Anti-HIV Agents; Female; HIV Infections; Humans; Lamivudine; Mitochondrial Myopathies; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Risk; Zidovudine

2000
Correlation between human immunodeficiency virus genotypic resistance and virologic response in patients receiving nelfinavir monotherapy or nelfinavir with lamivudine and zidovudine.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; Genotype; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Mutation; Nelfinavir; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Zidovudine

2000
Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.
    AIDS (London, England), 2000, Jul-07, Volume: 14, Issue:10

    Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; HIV Wasting Syndrome; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Stavudine; Time Factors; Zidovudine

2000
In vivo fluctuation of HTLV-I and HTLV-II proviral load in patients receiving antiretroviral drugs.
    Journal of acquired immune deficiency syndromes (1999), 2000, Jun-01, Volume: 24, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV-1; HTLV-I Infections; HTLV-II Infections; Human T-lymphotropic virus 1; Human T-lymphotropic virus 2; Humans; Lamivudine; Middle Aged; Proviruses; T-Lymphocytes; Viral Load; Zidovudine

2000
[Evaluation of the effect of early and massive tritherapy on the expression of cellular factors potentially implicated in antiretroviral therapy resistance].
    Pathologie-biologie, 2000, Volume: 48, Issue:5

    Topics: Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Microbial; Gene Expression; Indinavir; Lamivudine; Macaca fascicularis; Male; Nucleoside-Phosphate Kinase; RNA, Messenger; Simian Acquired Immunodeficiency Syndrome; Thymidine Kinase; Zidovudine

2000
[Conditions of "thymidine analog mutations" (TAMs) in naive patients treated with different combinations of d4T].
    Pathologie-biologie, 2000, Volume: 48, Issue:5

    Topics: Anti-HIV Agents; Drug Resistance; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zidovudine

2000
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].
    Antiviral chemistry & chemotherapy, 2000, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Drug Combinations; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Molecular Structure; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; T-Lymphocytes; Thionucleosides; Zidovudine

2000
The effect of highly active antiretroviral therapy on binding and neutralizing antibody responses to human immunodeficiency virus type 1 infection.
    The Journal of infectious diseases, 2000, Volume: 182, Issue:3

    Topics: Anti-HIV Agents; Carbamates; Dideoxynucleosides; Furans; HIV Antibodies; HIV Core Protein p24; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Lamivudine; Neutralization Tests; Ritonavir; Sulfonamides; Zidovudine

2000
Esophageal ulcer caused by cytomegalovirus: resolution during combination antiretroviral therapy for acquired immunodeficiency syndrome.
    Southern medical journal, 2000, Volume: 93, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Biopsy; CD4 Lymphocyte Count; Cytomegalovirus Infections; Drug Therapy, Combination; Endoscopy, Digestive System; Esophagitis; Humans; In Situ Hybridization; Lamivudine; Male; Nelfinavir; Ulcer; Wound Healing; Zidovudine

2000
Intensification of background antiretroviral therapy with abacavir during low-level failure may restore optimal suppression.
    Antiviral therapy, 2000, Volume: 5, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Dideoxynucleosides; Drug Resistance; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Failure; Viral Load; Zidovudine

2000
Dynamics of HIV-1 viral load rebound among patients with previous suppression of viral replication.
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Models, Biological; Predictive Value of Tests; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Virus Replication; Zidovudine

2000
Mitochondrial and peroxisomal dysfunction following perinatal exposure to antiretroviral drugs.
    AIDS (London, England), 2000, Jul-28, Volume: 14, Issue:11

    Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Mitochondria; Perinatal Care; Peroxisomes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine

2000
Immune reconstitution syndromes in human immuno-deficiency virus infection following effective antiretroviral therapy.
    Immunobiology, 2000, Volume: 202, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cytomegalovirus Retinitis; Female; Hepatitis C; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Mycobacterium avium-intracellulare Infection; Reverse Transcriptase Inhibitors; Zidovudine

2000
[Cost effectiveness analysis of highly active antiretroviral therapy in HIV asymptomatic patients].
    Medicina clinica, 2000, Volume: 114 Suppl 3

    Topics: Adult; Anti-HIV Agents; Cost-Benefit Analysis; Didanosine; Drug Therapy, Combination; Female; HIV Seropositivity; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nevirapine; Sickness Impact Profile; Spain; Stavudine; Viral Load; Zidovudine

2000
3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.
    Journal of virology, 2000, Volume: 74, Issue:20

    Topics: Animals; Anti-HIV Agents; COS Cells; Dose-Response Relationship, Drug; Drug Resistance; Genetic Vectors; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Zidovudine

2000
Postexposure prophylaxis for HIV after sexual assault.
    JAMA, 2000, Sep-27, Volume: 284, Issue:12

    Topics: Adult; Anti-HIV Agents; Chemoprevention; Female; HIV Infections; Humans; Lamivudine; Male; Retrospective Studies; San Francisco; Sex Offenses; Zidovudine

2000
Assessing efficacy by measuring CD(4) counts and quality of life of AIDS patients treated with ritonavir, AZT and 3TC.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2000, Volume: 4, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Body Weight; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Quality of Life; Ritonavir; Viral Load; Zidovudine

2000
Abacavir: new preparation. Risks limit the value.
    Prescrire international, 2000, Volume: 9, Issue:47

    Topics: Adult; Antiviral Agents; Child; Clinical Trials as Topic; Cost-Benefit Analysis; Dideoxynucleosides; Drug Hypersensitivity; Drug Interactions; Drug Therapy, Combination; France; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Risk Assessment; Treatment Outcome; Zidovudine

2000
Prevention of mother-child HIV transmission: progress and problems.
    Prescrire international, 2000, Volume: 9, Issue:47

    Topics: Africa; Antiviral Agents; Breast Feeding; Cesarean Section; Clinical Trials as Topic; Cohort Studies; Developing Countries; Drug Therapy, Combination; Europe; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mitochondrial Myopathies; Nervous System Diseases; Nevirapine; Pregnancy; Pregnancy Trimester, Third; Reverse Transcriptase Inhibitors; Thailand; United States; Zidovudine

2000
Brief report: effect of antiretroviral agents on T-lymphocyte subset counts in healthy HIV-negative individuals. The Italian Registry on Antiretroviral Postexposure Prophylaxis.
    Journal of acquired immune deficiency syndromes (1999), 2000, Aug-15, Volume: 24, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Health Personnel; HIV Infections; HIV Seronegativity; Humans; Lamivudine; Longitudinal Studies; Lymphocyte Count; Male; Occupational Diseases; Retrospective Studies; T-Lymphocyte Subsets; Zidovudine

2000
Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11

    Topics: Anti-HIV Agents; Chromatography, Ion Exchange; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; Humans; Lamivudine; Reference Standards; Thymine Nucleotides; Zidovudine

2000
Antiviral resistance of biologic HIV-2 clones obtained from individuals on nucleoside reverse transcriptase inhibitor therapy.
    Journal of acquired immune deficiency syndromes (1999), 2000, Sep-01, Volume: 25, Issue:1

    Topics: Adult; Amino Acid Sequence; Consensus Sequence; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Genes, Viral; Genotype; HIV Infections; HIV-2; Humans; Lamivudine; Male; Molecular Sequence Data; Phenotype; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zidovudine

2000
A genotypic analysis of patients receiving Zidovudine with either Lamivudine, Didanosine or Zalcitabine dual therapy using the LiPA point mutation assay to detect genotypic variation at codons 41, 69, 70, 74, 184 and 215.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2000, Volume: 19, Issue:3

    Topics: Anti-HIV Agents; Codon; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nucleic Acid Hybridization; Point Mutation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Zalcitabine; Zidovudine

2000
[Prevalence of primary mutations in human immunodeficiency virus with resistance to nucleoside analogues in previously untreated patients from Andalusia. Andalusian Group for the Study of Infectious diseases (GAEI)].
    Medicina clinica, 2000, Oct-07, Volume: 115, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4 Antigens; Codon; Data Interpretation, Statistical; DNA, Viral; Drug Resistance, Microbial; Female; Genotype; HIV; HIV Infections; Humans; Lamivudine; Male; Mutation; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Spain; Viral Load; Zidovudine

2000
Multicenter review of protease inhibitors in 89 pregnancies.
    Journal of acquired immune deficiency syndromes (1999), 2000, Dec-01, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Antiretroviral Therapy, Highly Active; Apgar Score; CD4-Positive T-Lymphocytes; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Linear Models; Multicenter Studies as Topic; Pregnancy; Pregnancy Complications, Infectious; Puerto Rico; Regression Analysis; Retrospective Studies; Reverse Transcriptase Inhibitors; Surveys and Questionnaires; United States; Viral Load; Zidovudine

2000
Sustained responses to dual nucleoside therapy in women.
    Journal of acquired immune deficiency syndromes (1999), 2000, Dec-01, Volume: 25, Issue:4

    Topics: Adult; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Viral Load; Zidovudine

2000
Simultaneous quantitation of the 5'-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2000, Volume: 11, Issue:12

    Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Mass Spectrometry; Monocytes; Reference Standards; Sensitivity and Specificity; Stavudine; Thymine Nucleotides; Zidovudine

2000
Oral lesions in HIV/AIDS patients undergoing highly active antiretroviral treatment including protease inhibitors: a new face of oral AIDS?
    AIDS patient care and STDs, 2000, Volume: 14, Issue:12

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Candidiasis, Oral; Case-Control Studies; CD4 Lymphocyte Count; Female; Gingivitis; Herpes Labialis; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Leukoplakia, Hairy; Male; Middle Aged; Mouth Diseases; Periodontitis; Prevalence; Viral Load; Xerostomia; Zidovudine

2000
Selective expansion of a minor proportion of drug-resistant HIV-1 by antiretroviral pressure in vitro.
    AIDS (London, England), 2000, Dec-01, Volume: 14, Issue:17

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Drug Resistance, Microbial; Genetic Variation; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Oligonucleotide Array Sequence Analysis; Phenotype; Reverse Transcriptase Inhibitors; Selection, Genetic; Zidovudine

2000
Reduction in CD8+ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Depression, Chemical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Hydroxyurea; Immunity, Cellular; Indinavir; Lamivudine; Lymphocyte Count; Male; Middle Aged; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Stavudine; Treatment Refusal; Viral Load; Viremia; Zidovudine

2001
From the food and drug administration.
    JAMA, 2001, Jan-03, Volume: 285, Issue:1

    Topics: Administrative Personnel; Anti-HIV Agents; Brachytherapy; Catheterization; Coronary Disease; Dideoxynucleosides; Drug Combinations; Equipment and Supplies; Humans; Lamivudine; Recurrence; Stents; Technology, Radiologic; United States; United States Food and Drug Administration; Zidovudine

2001
Protease inhibitor therapy in HIV-infected children.
    AIDS patient care and STDs, 2000, Volume: 14, Issue:11

    Topics: Adolescent; Age Factors; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Patient Compliance; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2000
Effects of prenatal AZT+3TC treatment on open field behavior and responsiveness to scopolamine in adult mice.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:3

    Topics: Animals; Behavior, Animal; Female; Lamivudine; Male; Mice; Muscarinic Antagonists; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Scopolamine; Zidovudine

2000
Trizivir on the market.
    Trends in microbiology, 2001, Volume: 9, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

2001
Prenatal exposure to anti-HIV drugs: neurobehavioral effects of zidovudine (AZT) + lamivudine (3TC) treatment in mice.
    Teratology, 2001, Volume: 63, Issue:1

    Topics: Animals; Anti-HIV Agents; Avoidance Learning; Body Weight; Female; Gestational Age; Hand Strength; Homing Behavior; Lamivudine; Male; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Reflex; Social Behavior; Zidovudine

2001
Primary HIV-1 drug resistance in Spain before and after the introduction of protease inhibitors.
    Journal of medical virology, 2001, Volume: 63, Issue:2

    Topics: Anti-HIV Agents; Codon; Drug Resistance, Microbial; Genotype; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Lamivudine; Mutation; Polymorphism, Genetic; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zidovudine

2001
Analysis of HIV-1 mutation patterns in patients failing antiretroviral therapy.
    Journal of clinical laboratory analysis, 2001, Volume: 15, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Mutation; Nelfinavir; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Saquinavir; Treatment Failure; Zidovudine

2001
Indinavir, zidovudine, lamivudine: 3-year follow-up.
    Annals of internal medicine, 2001, Jan-16, Volume: 134, Issue:2

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Kidney Calculi; Lamivudine; Risk Factors; Zidovudine

2001
Feasibility of postexposure prophylaxis (PEP) against human immunodeficiency virus infection after sexual or injection drug use exposure: the San Francisco PEP Study.
    The Journal of infectious diseases, 2001, Mar-01, Volume: 183, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Contact Tracing; Counseling; Didanosine; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Compliance; Reverse Transcriptase Inhibitors; Risk Factors; Risk-Taking; Sexually Transmitted Diseases, Viral; Substance Abuse, Intravenous; Time Factors; Zidovudine

2001
Increased turnover of CCR5+ and redistribution of CCR5- CD4 T lymphocytes during primary human immunodeficiency virus type 1 infection.
    The Journal of infectious diseases, 2001, Mar-01, Volume: 183, Issue:5

    Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Dideoxynucleosides; Epstein-Barr Virus Infections; Flow Cytometry; Furans; Genotype; HIV Infections; HIV-1; Humans; Immunoglobulin M; Lamivudine; Longitudinal Studies; Male; Proto-Oncogene Proteins c-bcl-2; Receptors, CCR5; Sulfonamides; Time Factors; Zidovudine

2001
Association between high serum prolactin levels and concomitant infections in HIV-infected patients.
    Human immunology, 2001, Volume: 62, Issue:2

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Anti-Infective Agents; CD4-CD8 Ratio; Female; HIV Infections; Humans; Immunoglobulins; Indinavir; Lamivudine; Male; Prolactin; Sex Factors; T-Lymphocyte Subsets; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Zidovudine

2001
FDA approves Trizivir for HIV infection.
    The AIDS reader, 2000, Volume: 10, Issue:12

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Approval; Drug Combinations; HIV Infections; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine

2000
Triple-drug tablet approved for HIV infection.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001, Jan-01, Volume: 58, Issue:1

    Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Dideoxynucleosides; Drug Combinations; Drug Labeling; HIV Infections; Humans; Lamivudine; Tablets; Zidovudine

2001
Serious adverse events attributed to nevirapine regimens for postexposure prophylaxis after HIV exposures--worldwide, 1997-2000.
    MMWR. Morbidity and mortality weekly report, 2001, Jan-05, Volume: 49, Issue:51-52

    Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; HIV Infections; Humans; Lamivudine; Liver Failure; Male; Nevirapine; Occupational Exposure; Reverse Transcriptase Inhibitors; Rhabdomyolysis; Zidovudine

2001
Treatment interruption after one year of triple nucleoside analogue therapy for primary HIV infection.
    AIDS (London, England), 2001, Jan-26, Volume: 15, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Time Factors; Viral Load; Zidovudine

2001
[Acquired immunodeficiency syndrome-associated progressive multifocal leukoencephalopathy treated with highly active anti-retroviral therapy].
    Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Aged; Antiretroviral Therapy, Highly Active; Humans; Indinavir; JC Virus; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Male; Treatment Outcome; Zidovudine

2000
In vitro evolution of the human immunodeficiency virus type 1 gag-protease region and maintenance of reverse transcriptase resistance following prolonged drug exposure.
    Journal of clinical microbiology, 2001, Volume: 39, Issue:3

    Topics: Drug Resistance, Microbial; Drug Resistance, Multiple; Evolution, Molecular; Gene Products, gag; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Microbial Sensitivity Tests; Molecular Sequence Data; Reverse Transcriptase Inhibitors; Zidovudine

2001
Quantification of HIV-1 proviral DNA in patients with undetectable plasma viremia over long-term highly active antiretroviral therapy.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2000, Volume: 4, Issue:4

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; DNA, Viral; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Polymerase Chain Reaction; Proviruses; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viremia; Zidovudine

2000
Primary genotypic and phenotypic HIV-1 drug resistance in recent seroconverters in Madrid.
    Journal of acquired immune deficiency syndromes (1999), 2001, Feb-01, Volume: 26, Issue:2

    Topics: Drug Resistance, Microbial; Drug Resistance, Multiple; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV Seropositivity; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Protease Inhibitors; Reverse Transcriptase Inhibitors; Spain; Viral Load; Zidovudine

2001
Prenatal AZT or 3TC and mouse development of locomotor activity and hot-plate responding upon administration of the GABA(A) receptor agonist muscimol.
    Psychopharmacology, 2001, Volume: 153, Issue:4

    Topics: Animals; Anti-HIV Agents; Female; GABA Agonists; GABA-A Receptor Agonists; Habituation, Psychophysiologic; Lamivudine; Male; Mice; Motor Activity; Muscimol; Pain Measurement; Pregnancy; Prenatal Exposure Delayed Effects; Reaction Time; Time Factors; Zidovudine

2001
[Bilateral hip necrosis, corticoids, and human immunodeficiency virus protease inhibitors].
    Enfermedades infecciosas y microbiologia clinica, 2001, Volume: 19, Issue:1

    Topics: Aged; Antiretroviral Therapy, Highly Active; Dexamethasone; Didanosine; Femur Head Necrosis; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Prednisone; Zidovudine

2001
Failure of postexposure prophylaxis after sexual exposure to HIV.
    AIDS (London, England), 2001, Feb-16, Volume: 15, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; Copulation; Female; HIV Antibodies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Treatment Failure; Viral Load; Zidovudine

2001
Residual human immunodeficiency virus (HIV) Type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years.
    The Journal of infectious diseases, 2001, May-01, Volume: 183, Issue:9

    Topics: Cohort Studies; DNA, Viral; Female; Genitalia; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Longitudinal Studies; Lymph Nodes; Male; Molecular Sequence Data; Randomized Controlled Trials as Topic; RNA, Viral; Time Factors; Viral Load; Viremia; Virus Replication; Zidovudine

2001
Reduced HIV-stimulated T-helper cell reactivity in cord blood with short-course antiretroviral treatment for prevention of maternal-infant transmission.
    Clinical and experimental immunology, 2001, Volume: 123, Issue:3

    Topics: Amino Acid Sequence; Anti-HIV Agents; Clinical Trials as Topic; Female; Fetal Blood; Gene Products, env; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Molecular Sequence Data; Peptide Fragments; South Africa; T-Lymphocytes, Helper-Inducer; Zidovudine

2001
[Management of pregnant women infected with HIV at Bichat Hospital between 1990 and 1998: analysis of 202 pregnancies].
    Gynecologie, obstetrique & fertilite, 2001, Volume: 29, Issue:3

    Topics: Africa South of the Sahara; Antiviral Agents; Cesarean Section; Female; France; Hepatitis B; Hepatitis C; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Papillomaviridae; Papillomavirus Infections; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Sexually Transmitted Diseases; Zidovudine

2001
Viral excretion in cervicovaginal secretions of HIV-1-infected women receiving antiretroviral therapy.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Viral; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Longitudinal Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Statistics, Nonparametric; Viral Load; Viremia; Virus Shedding; Zidovudine

2001
Combination prophylaxis for prevention of maternal-infant HIV transmission: beyond 076.
    JAMA, 2001, Apr-25, Volume: 285, Issue:16

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2001
Vertical HIV-1 transmission: prophylaxis and paediatric follow-up.
    Placenta, 2001, Volume: 22 Suppl A

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-HIV Agents; Didanosine; Drug Therapy, Combination; Female; Follow-Up Studies; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Ritonavir; Viral Load; Zidovudine

2001
Tolerability of postexposure prophylaxis with zidovudine, lamivudine, and nelfinavir for human immunodeficiency virus infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, May-15, Volume: 32, Issue:10

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Nelfinavir; Prospective Studies; Reverse Transcriptase Inhibitors; Zidovudine

2001
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
    The Journal of biological chemistry, 2001, Jun-29, Volume: 276, Issue:26

    Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Thymine Nucleotides; Zalcitabine; Zidovudine

2001
Impact of antiretroviral therapy on hepatitis C viraemia in HIV-infected patients.
    Antiviral therapy, 1996, Volume: 1, Issue:3

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Hepatitis C; HIV Infections; Humans; Lamivudine; RNA, Viral; Viremia; Zidovudine

1996
Results of long-term follow-up of HIV-infected patients treated with lamivudine monotherapy, followed by a combination of lamivudine and zidovudine.
    Antiviral therapy, 1997, Volume: 2, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Zidovudine

1997
Hypercholesterolemia in a health care worker receiving thyroxine after postexposure prophylaxis for human immunodeficiency virus infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jun-01, Volume: 32, Issue:11

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Interactions; Female; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Indinavir; Lamivudine; Nelfinavir; Occupational Exposure; Reverse Transcriptase Inhibitors; Thyroxine; Zidovudine

2001
AIDS treatments seek to eradicate virus, restore immunity.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:4

    Topics: Adjuvants, Immunologic; Anti-HIV Agents; Combined Modality Therapy; HIV Infections; Humans; Lamivudine; Ritonavir; Thymus Gland; Viral Load; Zidovudine

1996
3TC approved.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Drug Approval; Drug Therapy, Combination; Humans; Lamivudine; Zidovudine

1996
Research study of combination AIDS therapies underway.
    AIDS patient care and STDs, 1996, Volume: 10, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; Humans; Lamivudine; Zidovudine

1996
ACTG 315 drug cocktail restores immune function.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:3

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Ritonavir; RNA, Viral; Viral Load; Zidovudine

1997
Undetectable HIV levels after triple therapy with indinavir.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; RNA, Viral; Viral Load; Zidovudine

1997
ACTG 320 trial halted as three-drug arm proves superior.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; United States; Zidovudine

1997
Anti-HIV effects of nelfinavir reported after ten months of combination therapy.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:4

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphoid Tissue; Nelfinavir; Zidovudine

1997
HAART therapy: dividing the epidemic?
    AIDS patient care and STDs, 1997, Volume: 11, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Zidovudine

1997
First clinical data presented on FortovAse.
    AIDS patient care and STDs, 1997, Volume: 11, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Saquinavir; Zidovudine

1997
Ritonavir pediatric study results reported.
    AIDS patient care and STDs, 1998, Volume: 12, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Ritonavir; Zidovudine

1998
Head-to-head study of protease inhibitors.
    AIDS patient care and STDs, 1998, Volume: 12, Issue:1

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Zidovudine

1998
Data in from first head-to-head protease inhibitor.
    AIDS patient care and STDs, 1998, Volume: 12, Issue:4

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Viral Load; Zidovudine

1998
Double protease inhibitor regimens with amprenavir show promise.
    AIDS patient care and STDs, 1998, Volume: 12, Issue:4

    Topics: Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Sulfonamides; Viral Load; Zidovudine

1998
AZT studies reinforce benefits of combination.
    AIDS alert, 1995, Volume: 10, Issue:1

    Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Didanosine; Drug Synergism; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Lymphocyte Count; Zalcitabine; Zidovudine

1995
Combination 3TC/AZT therapy shows promise.
    AIDS clinical care, 1995, Volume: 7, Issue:3

    Topics: CD4 Lymphocyte Count; Codon; Drug Resistance; Drug Therapy, Combination; Drug Tolerance; HIV Infections; Humans; Lamivudine; Mutation; Zalcitabine; Zidovudine

1995
Clinical progress and transmission perils stressed at second human retroviruses conference.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:2

    Topics: Acyclovir; AIDS Vaccines; AIDS-Related Opportunistic Infections; Antineoplastic Agents; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Herpesviridae; HIV Infections; Humans; Interleukin-2; Lamivudine; Lymphoma, Non-Hodgkin; Retroviridae; Sarcoma, Kaposi; Zalcitabine; Zidovudine

1995
AIDS task force grapples with faster access to protease drugs.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Approval; Drug Design; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Treatment Outcome; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1995
AZT + 3TC: early results promising.
    Common factor (Stoughton, Mass.), 1995, Issue:no 10

    Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamivudine; Zalcitabine; Zidovudine

1995
Treatment briefs.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:4

    Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Industry; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Nerve Growth Factors; Nervous System Diseases; Pyridines; Recombinant Proteins; Stavudine; Zalcitabine; Zidovudine

1995
3TC: the good news and the bad news.
    PI perspective, 1995, Issue:no 16

    Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; Europe; HIV Infections; Humans; Lamivudine; United States; Zalcitabine; Zidovudine

1995
What we know about anti-HIV drugs.
    Treatment review, 1995, Issue:no 18

    Topics: Antiviral Agents; Didanosine; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Zalcitabine; Zidovudine

1995
Lamivudine useful against hepatitis B-HIV co-infection.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:5

    Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Hepatitis B; Hepatitis B virus; HIV Infections; Humans; Lamivudine; Virus Replication; Zalcitabine; Zidovudine

1995
Combination antiretroviral treatment: new views, evolving practices.
    AIDS treatment news, 1995, Jul-07, Issue:no 226

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Cells, Cultured; Clinical Trials as Topic; Drug Administration Schedule; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1995
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Jul-07, Issue:no 226

    Topics: Acyclovir; Administration, Oral; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1995
Combination treatment and single drugs: interview with Margaret Poscher, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Jul-21, Issue:no 227

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Approval; Drug Combinations; Drug Therapy, Combination; Health Services Accessibility; Humans; Insurance, Health; Lamivudine; Managed Care Programs; United States; Zalcitabine; Zidovudine

1995
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
    AIDS treatment news, 1995, Aug-04, Issue:no 228

    Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1995
3TC: now available again up to CD4 of 300.
    AIDS treatment news, 1995, Aug-04, Issue:no 228

    Topics: Acquired Immunodeficiency Syndrome; CD4 Lymphocyte Count; Drug Industry; Drug Therapy, Combination; Humans; Lamivudine; Patient Selection; United States; Zalcitabine; Zidovudine

1995
A closer look at 3TC. Interview by Mark Mascolini.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:6

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Hepatitis B; HIV Infections; Humans; Lamivudine; Zalcitabine; Zidovudine

1995
Antiretroviral drug resistance.
    AIDS clinical care, 1995, Volume: 7, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; RNA, Viral; Stavudine; Viremia; Zalcitabine; Zidovudine

1995
A Lisbon traviata. Are clinicians ready to sing addio to monotherapy and libiamo to combinations?
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; HIV; HIV Infections; Humans; Hydroxyurea; Indinavir; Interleukin-2; Lamivudine; Mutation; Pyridines; RNA, Viral; Zalcitabine; Zidovudine

1995
Update on clinical trials of combination therapies for HIV infection.
    NIAID AIDS agenda, 1995

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; RNA-Directed DNA Polymerase; Stavudine; Zalcitabine; Zidovudine

1995
Protease inhibitors and prevention of cross resistance.
    AIDS treatment news, 1995, Oct-06, Issue:no 232

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Carbamates; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nelfinavir; Pyridines; Quinolines; Saquinavir; Sulfonamides; Zalcitabine; Zidovudine

1995
3TC and saquinavir: we need them now.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1995

    Topics: Antiviral Agents; Drug Approval; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1995
Conference looks at HIV drug resistance.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:9

    Topics: Antiviral Agents; Carbamates; CD4 Lymphocyte Count; Drug Resistance, Microbial; Furans; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Sulfonamides; Thiazoles; Valine; Viremia; Zalcitabine; Zidovudine

1995
Roaches of inner space.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Lamivudine; Mutation; T-Lymphocytes, Cytotoxic; Virulence; Virus Replication; Zalcitabine; Zidovudine

1995
An interview with Charles A.B. Boucher, MD, PhD. Interview by Mark Mascolini.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:10

    Topics: Antiviral Agents; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Mutation; RNA, Viral; Zalcitabine; Zidovudine

1995
FDA triple header. Food and Drug Administration.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Mutation; Quinolines; Salvage Therapy; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1995
3TC/AZT: just another combination.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:12

    Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Zalcitabine; Zidovudine

1995
Combination therapy increases survival.
    Treatment review, 1995, Issue:no 20

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1995
Lamivudine (3TC) approved for combination use with AZT.
    AIDS treatment news, 1995, Dec-01, Issue:no 236

    Topics: Adult; Antiviral Agents; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Zalcitabine; Zidovudine

1995
To treat or not to treat--approaches to antiretroviral therapy. Interview by Anthony J. Japour.
    AIDS clinical care, 1996, Volume: 8, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Didanosine; Drug Therapy, Combination; HIV; Humans; Lamivudine; Practice Patterns, Physicians'; RNA, Viral; Zalcitabine; Zidovudine

1996
Major protease inhibitor triple combination trial begins soon: CD4 under 200, AZT experienced, 3TC naive.
    AIDS treatment news, 1995, Dec-22, Issue:no 237

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Zalcitabine; Zidovudine

1995
3TC approved: now for the tough questions.
    Journal of the International Association of Physicians in AIDS Care, 1995, Volume: 1, Issue:11

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Zalcitabine; Zidovudine

1995
Merck protease inhibitor: more news from Retroviruses Conference.
    AIDS treatment news, 1996, Feb-16, Issue:no 241

    Topics: CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Zalcitabine; Zidovudine

1996
Potent new AIDS drugs underscore promise of combination therapy.
    AIDS alert, 1996, Volume: 11, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Approval; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine

1996
Clinicians experiment with post-exposure drug pairs.
    AIDS alert, 1996, Volume: 11, Issue:2

    Topics: Antiviral Agents; Drug Synergism; Drug Therapy, Combination; Health Personnel; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Needlestick Injuries; Occupational Exposure; Zalcitabine; Zidovudine

1996
Protease inhibitors shine in triple combinations.
    AIDS alert, 1996, Volume: 11, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Pyridines; Ritonavir; Thiazoles; Valine; Zalcitabine; Zidovudine

1996
Europe out of step with the US.
    Journal of the International Association of Physicians in AIDS Care, 1996, Volume: 2, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Costs; Europe; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Ritonavir; Saquinavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine

1996
Back to the nukes.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:2

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1996
A surprisingly potent nucleoside analogue.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:2

    Topics: Adult; Antiviral Agents; HIV Infections; HIV-1; Humans; Lamivudine; Nucleosides; RNA, Viral; Zalcitabine; Zidovudine

1996
AZT and 3TC.
    Treatment review, 1996, Issue:no 21

    Topics: CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zalcitabine; Zidovudine

1996
CDC takes aggressive stance on postexposure prophylaxis. Centers for Disease Control and Prevention.
    AIDS alert, 1996, Volume: 11, Issue:7

    Topics: Antiviral Agents; Blood-Borne Pathogens; Centers for Disease Control and Prevention, U.S.; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Exposure; Pyridines; Risk Factors; United States; Zalcitabine; Zidovudine

1996
Nipping HIV in the bud.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:8

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine

1996
Top AIDS researchers' strategy for antiretroviral treatment.
    AIDS alert, 1996, Volume: 11, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Patient Compliance; Practice Guidelines as Topic; RNA, Viral; Stavudine; Zalcitabine; Zidovudine

1996
3TC: combination trial stopped early as clinical benefit shown.
    AIDS treatment news, 1996, Aug-02, Issue:no 252

    Topics: Antiviral Agents; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Placebos; Treatment Failure; Zalcitabine; Zidovudine

1996
Eradication of HIV: the cutting edge of clinical trial design.
    Critical Path AIDS project, 1996,Fall, Issue:No 31

    Topics: Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Pyridines; Zalcitabine; Zidovudine

1996
Outdated yet out-of-reach: AIDS society treatment guidelines at the International Conference.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Decision Making; Didanosine; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Zalcitabine; Zidovudine

1996
Update on antivirals.
    PI perspective, 1996, Issue:No 19

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

1996
New findings bring hope to Vancouver AIDS conference.
    NIAID AIDS agenda, 1996

    Topics: Adult; AIDS Vaccines; Antiviral Agents; Clinical Trials as Topic; Developing Countries; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Viral Load; Zidovudine

1996
ddI and d4T plus protease inhibitors.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:11

    Topics: Anti-HIV Agents; Didanosine; HIV Infections; Humans; Lamivudine; Stavudine; Zalcitabine; Zidovudine

1996
Dethroning AZT.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Hydroxyurea; Lamivudine; Oxazines; Stavudine; Viral Load; Zidovudine

1997
Study shows three drugs better than two.
    AIDS alert, 1997, Volume: 12, Issue:4

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Stavudine; United States; Zidovudine

1997
Study confirms that protease inhibitor cocktail can delay HIV disease progression and death.
    NIAID AIDS agenda, 1997

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; United States; Zidovudine

1997
NIAID researchers present new findings at retrovirus meeting. National Institute of Allergy and Infectious Diseases.
    NIAID AIDS agenda, 1997

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Chemokines; Clinical Trials as Topic; Clone Cells; Dendritic Cells; Didanosine; Disease Progression; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Interleukin-10; Killer Cells, Natural; Lamivudine; Male; Nevirapine; Pyridines; Receptors, Cytokine; Reverse Transcriptase Inhibitors; Ritonavir; Virus Replication; Zalcitabine; Zidovudine

1997
Nelfinavir at six months.
    PI perspective, 1997, Issue:No 21

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Sulfonic Acids; Viral Load; Zidovudine

1997
ACTG 320: last of the body count trials?
    PI perspective, 1997, Issue:No 21

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; Ethics, Medical; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zidovudine

1997
Nelfinavir - major trial results at retroviruses conference.
    AIDS treatment news, 1997, Feb-21, Issue:No 265

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Stavudine; Sulfonic Acids; Viral Load; Zidovudine

1997
New recommendations on health care worker exposure to HIV.
    STEP perspective, 1996,Fall, Volume: 8, Issue:3

    Topics: Anti-HIV Agents; Disease Transmission, Infectious; Drug Therapy, Combination; Guidelines as Topic; Health Personnel; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Risk Factors; Viral Load; Zidovudine

1996
Spring cleaning in trial land.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:3

    Topics: Anti-HIV Agents; Brazil; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Stavudine; United States; Viral Load; Zidovudine

1997
Newly approved PI provides treatment options.
    AIDS alert, 1997, Volume: 12, Issue:6

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Nelfinavir; Sulfonic Acids; Viral Load; Zidovudine

1997
Treating a survivor.
    AIDS clinical care, 1997, Volume: 9, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Counseling; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mycobacterium avium-intracellulare Infection; Pneumonia, Pneumocystis; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine

1997
3-drug therapy reduces deaths and new AIDS-related illnesses by 50%.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1997

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

1997
Nelfinavir (Viracept).
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1997

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Approval; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Isoquinolines; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Sulfonic Acids; United States; United States Food and Drug Administration; Viral Load; Virus Replication; Zidovudine

1997
141 (Vertex-478).
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1997

    Topics: Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Clinical Trials, Phase II as Topic; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Sulfonamides; Viral Load; Zidovudine

1997
Experience with PEP finds most patients stop early.
    AIDS alert, 1997, Volume: 12, Issue:9

    Topics: Anti-HIV Agents; British Columbia; Drug Therapy, Combination; Female; Health Services Accessibility; HIV Infections; Homosexuality, Male; Humans; Lamivudine; Male; Occupational Diseases; Patient Compliance; Sexually Transmitted Diseases; Time Factors; United States; Zidovudine

1997
Combo therapy for children and adolescents.
    Treatment review, 1997, Issue:No 25

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Clinical Trials as Topic; Didanosine; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Infant; Lamivudine; Zidovudine

1997
Two drugs better than one for children.
    AIDS alert, 1997, Volume: 12, Issue:10

    Topics: Anti-HIV Agents; Child; Disease Progression; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Zidovudine

1997
What you need to know about Combivir.
    AIDS alert, 1998, Volume: 13, Issue:1

    Topics: Anti-HIV Agents; Drug Combinations; Guidelines as Topic; HIV Infections; Humans; Lamivudine; Patient Compliance; Zidovudine

1998
ACTG 343: three drugs better than two for maintaining HIV suppression.
    NIAID AIDS agenda, 1998

    Topics: AIDS Vaccines; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Viral Load; Zidovudine

1998
New ways to take old drugs.
    STEP perspective, 1998,Winter, Volume: 98, Issue:1

    Topics: Anti-HIV Agents; Biological Availability; Drug Combinations; Drug Storage; HIV Infections; Humans; Lamivudine; Saquinavir; Zidovudine

1998
Reevaluating initial therapy.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1998, Volume: 12, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Polymerase Chain Reaction; Stavudine; Viral Load; Zidovudine

1998
New drugs: amprenavir and abacavir.
    TreatmentUpdate, 1998, Volume: 10, Issue:2

    Topics: Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Sulfonamides; Viral Load; Zidovudine

1998
New guidelines issued for occupational exposures.
    AIDS policy & law, 1998, May-29, Volume: 13, Issue:10

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Occupational Exposure; Practice Guidelines as Topic; United States; United States Public Health Service; Zidovudine

1998
Giving improper dose of HIV drug is not proof of indifference.
    AIDS policy & law, 1998, Jun-26, Volume: 13, Issue:12

    Topics: Anti-HIV Agents; Disabled Persons; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Prisoners; Reverse Transcriptase Inhibitors; Texas; Zidovudine

1998
Updated postexposure guidelines stress need for expert advice.
    AIDS alert, 1998, Volume: 13, Issue:7

    Topics: Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Drug Therapy, Combination; Female; Guidelines as Topic; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Occupational Diseases; Occupational Exposure; Pregnancy; Registries; United States; Zidovudine

1998
Registry finds 3 drugs most favored PEP regimen.
    AIDS alert, 1998, Volume: 13, Issue:7

    Topics: Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Drug Combinations; Drug Therapy, Combination; Guidelines as Topic; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Diseases; Occupational Exposure; Registries; United States; Zidovudine

1998
New drugs on the horizon.
    Project Inform perspective, 1998, Issue:24

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; Sulfonamides; United States; Zidovudine

1998
Lower dose maintenance therapy?
    Project Inform perspective, 1998, Issue:24

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; RNA, Viral; Viral Load; Zidovudine

1998
First once-daily drug simplifies dosing, offers new options in HIV-1 treatment.
    AIDS alert, 1998, Volume: 13, Issue:11

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Cyclopropanes; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Oxazines; Patient Compliance; Reverse Transcriptase Inhibitors; Zidovudine

1998
A new approach to initial antiretroviral therapy: protease-sparing combination regimens.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998

    Topics: Alkynes; Anti-HIV Agents; Antineoplastic Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Drugs, Investigational; HIV Infections; HIV Protease Inhibitors; Humans; Hydroxyurea; Lamivudine; Lipodystrophy; Oxazines; Reverse Transcriptase Inhibitors; Time Factors; Zidovudine

1998
Triple-drug therapy may mean lifelong commitment.
    AIDS alert, 1999, Volume: 14, Issue:1

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; France; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Patient Compliance; United States; Zidovudine

1999
A new HAART on the horizon says the proof is in the potency.
    AIDS alert, 1999, Volume: 14, Issue:4

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Oxazines; Patient Compliance; Pregnancy; Reverse Transcriptase Inhibitors; Zidovudine

1999
New study shows efavirenz effective with d4T and 3TC.
    AIDS alert, 1999, Volume: 14, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cerebrospinal Fluid; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Oxazines; Reverse Transcriptase Inhibitors; Stavudine; Vagina; Viral Load; Zidovudine

1999
Promising findings from the PETRA study of perinatal transmission.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1999, Volume: 12, Issue:2

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Randomized Controlled Trials as Topic; South Africa; Tanzania; Uganda; Zidovudine

1999
Antiretrovirals for HIV nephropathy?
    AIDS clinical care, 1999, Volume: 11, Issue:6

    Topics: Adult; AIDS-Associated Nephropathy; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Kidney Function Tests; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

1999
Nukes alone.
    TreatmentUpdate, 1999, Aug-01, Volume: 11, Issue:6

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Administration Schedule; Drug Therapy, Combination; France; HIV Infections; Humans; Lamivudine; Zidovudine

1999
[A rare etiology of hepatic steatosis associated with lactic acidosis: the toxicity of antiviral nucleoside analogues].
    Annales de pathologie, 2001, Volume: 21, Issue:2

    Topics: Acidosis, Lactic; Adult; Anti-HIV Agents; Antimetabolites; Didanosine; Fatal Outcome; Fatty Liver; Female; HIV Seropositivity; Humans; Lamivudine; Microscopy, Electron; Mitochondria, Liver; Stavudine; Zidovudine

2001
[Compact therapy with 2 tablets daily. Initial triple combination tablet simplifies HIV therapy].
    MMW Fortschritte der Medizin, 2001, Apr-02, Volume: 143 Suppl 1

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; HIV Infections; Humans; Lamivudine; Patient Compliance; Zidovudine

2001
[Results of the TRIZAL Study. Therapy change with positive concomitant effect].
    MMW Fortschritte der Medizin, 2001, Apr-02, Volume: 143 Suppl 1

    Topics: Anti-HIV Agents; Cholesterol; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Treatment Outcome; Triglycerides; Zidovudine

2001
Residual human immunodeficiency virus type 1 infection in lymphoid tissue during highly active antiretroviral therapy: quantitation and virus characterization.
    AIDS research and human retroviruses, 2001, May-01, Volume: 17, Issue:7

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Disease Progression; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Longitudinal Studies; Lymphoid Tissue; Phenotype; Proviruses; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Viral Load; Viremia; Virus Replication; Zidovudine

2001
CT appearances of HIV-related lipodystrophy syndrome.
    The British journal of radiology, 2001, Volume: 74, Issue:880

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Mass Index; HIV Infections; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Tomography, X-Ray Computed; Treatment Outcome; Zidovudine

2001
Choosing which nuke to use first.
    The AIDS reader, 2001, Volume: 11, Issue:5

    Topics: Didanosine; Dideoxynucleosides; Drug Administration Schedule; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2001
Domestic cat model for predicting human nucleoside analogue pharmacokinetics in blood and seminal plasma.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:7

    Topics: Animals; Anti-HIV Agents; Cats; Humans; Lamivudine; Male; Models, Animal; Semen; Zidovudine

2001
Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs.
    AIDS research and human retroviruses, 2001, Jun-10, Volume: 17, Issue:9

    Topics: Amino Acid Sequence; Anti-HIV Agents; Base Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Evolution, Molecular; Genetic Heterogeneity; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Insertional; Phylogeny; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Time Factors; Zidovudine

2001
[Symptomatic hyperlactemia in patients infected with the human immunodeficiency virus treated with nucleoside analogs].
    Medicina clinica, 2001, Jun-09, Volume: 117, Issue:1

    Topics: Adult; Anti-HIV Agents; Didanosine; Female; HIV Infections; HIV Reverse Transcriptase; Humans; Lactic Acid; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zidovudine

2001
Prevalence and predictive value of intermittent viremia with combination hiv therapy.
    JAMA, 2001, Jul-11, Volume: 286, Issue:2

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Microbial; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Predictive Value of Tests; Prevalence; Proportional Hazards Models; Retrospective Studies; RNA, Viral; Viral Load; Viremia; Virus Replication; Zidovudine

2001
Long-term evaluation of T-cell subset changes after effective combination antiretroviral therapy during asymptomatic HIV-infection.
    Journal of acquired immune deficiency syndromes (1999), 2001, Jul-01, Volume: 27, Issue:3

    Topics: Anti-HIV Agents; Case-Control Studies; Female; HIV Infections; HLA-DR Antigens; Humans; Lamivudine; Leukocyte Common Antigens; Longitudinal Studies; Lymphocyte Count; Male; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Ritonavir; T-Lymphocyte Subsets; Viral Load; Zidovudine

2001
Potent antiretroviral therapy initiates normalization of hypergammaglobulinemia and a decline in HIV type 1-specific antibody responses.
    AIDS research and human retroviruses, 2001, Jul-20, Volume: 17, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV Antibodies; HIV Core Protein p24; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Hypergammaglobulinemia; Immunoglobulin G; Lamivudine; Male; Middle Aged; Retrospective Studies; Ritonavir; RNA, Viral; Treatment Failure; Viral Load; Zidovudine

2001
Lipid abnormalities in a healthcare worker receiving HIV prophylaxis.
    International journal of STD & AIDS, 2001, Volume: 12, Issue:8

    Topics: Adult; Allied Health Personnel; Anti-HIV Agents; Cholesterol; Cholesterol, LDL; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Lamivudine; Needlestick Injuries; Nelfinavir; Practice Guidelines as Topic; Renal Dialysis; Reverse Transcriptase Inhibitors; Zidovudine

2001
Neurological disorders after zidovudine exposure in utero.
    Prescrire international, 1999, Volume: 8, Issue:44

    Topics: Female; France; HIV Infections; Humans; Infant, Newborn; Lamivudine; Mitochondria; Neurotoxicity Syndromes; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies; United States; Zidovudine

1999
Differential susceptibility of retroviruses to nucleoside analogues.
    Antiviral chemistry & chemotherapy, 2001, Volume: 12, Issue:2

    Topics: Animals; Antiviral Agents; Cell Line; Cricetinae; Didanosine; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lamivudine; Mink; Nucleosides; Retroviridae; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Zalcitabine; Zidovudine

2001
Antiretroviral rounds. When success is a pain.
    AIDS clinical care, 2001, Volume: 13, Issue:8

    Topics: Abdominal Pain; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Oxazines; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2001
Approval comes with warning.
    AIDS patient care and STDs, 2001, Volume: 15, Issue:2

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Approval; Drug Combinations; Drug Hypersensitivity; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine

2001
An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy.
    Neurology, 2001, Sep-25, Volume: 57, Issue:6

    Topics: Adult; Anti-HIV Agents; Brain; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Magnetic Resonance Imaging; Motor Neuron Disease; Nelfinavir; Neurologic Examination; Treatment Outcome; Zidovudine

2001
[Acceptance of antiretroviral therapy. HIV-infected patients assess convenient triple combination].
    MMW Fortschritte der Medizin, 2001, Sep-06, Volume: 143, Issue:35-36

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Patient Acceptance of Health Care; Patient Compliance; Zidovudine

2001
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.
    The Journal of infectious diseases, 2001, Nov-15, Volume: 184, Issue:10

    Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; HIV Infections; HIV-1; Lamivudine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Thymine Nucleotides; Transfection; Zidovudine

2001
Combined effect of zidovudine (ZDV), lamivudine (3TC) and abacavir (ABC) antiretroviral therapy in suppressing in vitro FIV replication.
    Antiviral research, 2002, Volume: 53, Issue:1

    Topics: Animals; Anti-HIV Agents; Cats; Cell Line; Dideoxynucleosides; Drug Synergism; Drug Therapy, Combination; Feline Acquired Immunodeficiency Syndrome; Humans; Hydroxyurea; Immunodeficiency Virus, Feline; Kidney; Lamivudine; Reverse Transcriptase Inhibitors; Virus Replication; Zidovudine

2002
Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice.
    Laboratory investigation; a journal of technical methods and pathology, 2001, Volume: 81, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atrial Natriuretic Factor; Calcium-Transporting ATPases; Cardiomyopathies; Drug Therapy, Combination; Echocardiography; Gene Expression; HIV Protease Inhibitors; Indinavir; Lactic Acid; Lamivudine; Mice; Mice, Transgenic; Microscopy, Electron; Myocardium; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Zidovudine

2001
Absolute lymphocyte count as surrogate for CD4+ cell count in monitoring response to antiretroviral therapy.
    The Nigerian postgraduate medical journal, 2001, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Lamivudine; Lymphocyte Count; Male; Middle Aged; Sensitivity and Specificity; Time Factors; Zidovudine

2001
A case of lipodystrophy after the initiation of zidovudine, lamivudine and efavirenz in an asymptomatic HIV-1-infected patient.
    HIV medicine, 2000, Volume: 1, Issue:3

    Topics: Abdomen; Adipose Tissue; Adult; Alkynes; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Lipodystrophy; Male; Oxazines; Reverse Transcriptase Inhibitors; Tomography, X-Ray Computed; Zidovudine

2000
Prediction of abacavir resistance from genotypic data: impact of zidovudine and lamivudine resistance in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1

    Topics: Algorithms; Anti-HIV Agents; Dideoxynucleosides; Drug Resistance, Microbial; Gene Frequency; Genotype; HIV; Humans; Lamivudine; Microbial Sensitivity Tests; Zidovudine

2002
Summaries for patients. Predictors of outcomes in patients with HIV infection treated with indinavir, zidovudine, and lamivudine.
    Annals of internal medicine, 2001, Dec-04, Volume: 135, Issue:11

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Protocols; Disease Progression; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; RNA, Viral; Viral Load; Zidovudine

2001
Prevalence and genetic heterogeneity of the reverse transcriptase T69S-S-X insertion in pretreated HIV-infected patients.
    Intervirology, 2001, Volume: 44, Issue:6

    Topics: Anti-HIV Agents; Didanosine; Drug Resistance, Viral; Genetic Heterogeneity; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Mutagenesis; Prevalence; Reverse Transcriptase Inhibitors; Spain; Zidovudine

2001
Complete remission of AIDS/Kaposi's sarcoma after treatment with a combination of two nucleoside reverse transcriptase inhibitors and one non-nucleoside reverse transcriptase inhibitor.
    AIDS (London, England), 2002, Jan-25, Volume: 16, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; HIV-1; Homosexuality, Male; Humans; Lamivudine; Male; Nucleosides; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Sarcoma, Kaposi; Treatment Outcome; Viral Load; Zidovudine

2002
Low-rate emergence of thymidine analogue mutations and multi-drug resistance mutations in the HIV-1 reverse transcriptase gene in therapy-naive patients receiving stavudine plus lamivudine combination therapy.
    Antiviral therapy, 2001, Volume: 6, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Genotype; HIV Reverse Transcriptase; Humans; Lamivudine; Mutation; Stavudine; Viral Load; Zidovudine

2001
Clinical trials group: two studies are now open to patients who qualify.
    HIV clinician, 2000,Winter, Volume: 12, Issue:1

    Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Oxazines; Patient Selection; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Zidovudine

2000
Resistance to antiretroviral treatment in Gabon: need for implementation of guidelines on antiretroviral therapy use and HIV-1 drug resistance monitoring in developing countries.
    Journal of acquired immune deficiency syndromes (1999), 2002, Feb-01, Volume: 29, Issue:2

    Topics: Anti-HIV Agents; Developing Countries; Didanosine; Drug Resistance, Viral; Gabon; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Population Surveillance; Practice Guidelines as Topic; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2002
Regression of HIV-associated pulmonary arterial hypertension and long-term survival during antiretroviral therapy.
    Swiss medical weekly, 2001, Dec-01, Volume: 131, Issue:45-46

    Topics: Adult; Anti-HIV Agents; Anticoagulants; Drug Therapy, Combination; Echocardiography; Follow-Up Studies; HIV Infections; Humans; Hypertension, Pulmonary; Lamivudine; Male; Nelfinavir; Severity of Illness Index; Stavudine; Treatment Outcome; Zidovudine

2001
Recurrent hypersensitivity to Combivir.
    International journal of STD & AIDS, 2002, Volume: 13, Issue:3

    Topics: Adult; Anti-HIV Agents; Drug Combinations; Drug Hypersensitivity; Female; HIV Infections; HIV-1; Humans; Lamivudine; Recurrence; Zidovudine

2002
Mycobacterium xenopi pulmonary infection in an HIV infected patient under highly active antiretroviral treatment.
    Sexually transmitted infections, 2002, Volume: 78, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Combinations; Female; Humans; Immunocompromised Host; Lamivudine; Lung Diseases; Mycobacterium Infections, Nontuberculous; Mycobacterium xenopi; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

2002
Parallel decline of CD8+/CD38++ T cells and viraemia in response to quadruple highly active antiretroviral therapy in primary HIV infection.
    AIDS (London, England), 2002, Mar-08, Volume: 16, Issue:4

    Topics: Adult; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Biomarkers; Carbamates; CD48 Antigen; CD8-Positive T-Lymphocytes; Dideoxynucleosides; Female; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymphocyte Count; Male; Middle Aged; Reverse Transcriptase Inhibitors; Sulfonamides; T-Lymphocyte Subsets; Treatment Outcome; Viral Load; Viremia; Zidovudine

2002
The pharmacokinetics of methadone following co-administration with a lamivudine/zidovudine combination tablet in opiate-dependent subjects.
    The American journal on addictions, 2002,Winter, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Drug Combinations; Female; HIV Seropositivity; Humans; Lamivudine; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Zidovudine

2002
Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys.
    Journal of acquired immune deficiency syndromes (1999), 2002, Apr-01, Volume: 29, Issue:4

    Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; DNA; DNA Damage; Erythrocebus patas; Female; Fetus; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Maternal-Fetal Exchange; Placenta; Pregnancy; Reverse Transcriptase Inhibitors; Telomere; Zidovudine

2002
Is AZT/3TC therapy effective against FIV infection or immunopathogenesis?
    Veterinary immunology and immunopathology, 2002, Volume: 85, Issue:3-4

    Topics: Animals; Anti-HIV Agents; Antibodies, Viral; Cat Diseases; Cats; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Synergism; Drug Therapy, Combination; Feline Acquired Immunodeficiency Syndrome; Flow Cytometry; Immunodeficiency Virus, Feline; Lamivudine; Random Allocation; Viral Load; Zidovudine

2002
Switching to zidovudine plus lamivudine plus abacavir maintains viral suppression in patients with high viral load before antiretroviral therapy: a retrospective clinical cohort analysis.
    AIDS (London, England), 2002, May-03, Volume: 16, Issue:7

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Dideoxynucleosides; Drug Evaluation; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; London; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Viremia; Zidovudine

2002
[Post-exposure prophylaxis in Zambia; the experiences of a tropical disease specialist following a cut accidentally incurred while operating on an HIV positive patient].
    Nederlands tijdschrift voor geneeskunde, 2002, Mar-30, Volume: 146, Issue:13

    Topics: Adult; Anti-HIV Agents; Health Personnel; HIV Infections; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Reverse Transcriptase Inhibitors; Zambia; Zidovudine

2002
DPC 817: a cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variants.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:5

    Topics: Animals; Anti-HIV Agents; Cytidine; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Macaca mulatta; Nucleosides; Reverse Transcriptase Inhibitors; Zalcitabine; Zidovudine

2002
The human 26S proteasome is a target of antiretroviral agents.
    AIDS (London, England), 2002, Mar-29, Volume: 16, Issue:5

    Topics: Anti-HIV Agents; DNA-Binding Proteins; Drug Delivery Systems; HIV Protease Inhibitors; Humans; I-kappa B Proteins; Indinavir; Jurkat Cells; Lamivudine; NF-kappa B; NF-KappaB Inhibitor alpha; Peptide Hydrolases; Proteasome Endopeptidase Complex; Reverse Transcriptase Inhibitors; Ubiquitin; Zidovudine

2002
Improved long-term suppression of HIV-1 replication with a triple-class multidrug regimen compared with standard of care antiretroviral therapy.
    AIDS (London, England), 2002, Mar-29, Volume: 16, Issue:5

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Follow-Up Studies; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load; Virus Replication; Zidovudine

2002
Genotypic drug resistance during HIV-1 primary infection in France (1996-1999): frequency and response to treatment.
    AIDS (London, England), 2002, Mar-29, Volume: 16, Issue:5

    Topics: Adult; Antiretroviral Therapy, Highly Active; Cohort Studies; Drug Resistance, Viral; Female; France; Genotype; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Ritonavir; RNA, Viral; Viral Load; Zidovudine

2002
[Drug combination therapy for children infected with HIV/AIDS--own experience].
    Przeglad epidemiologiczny, 2001, Volume: 55 Suppl 3

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Didanosine; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Nelfinavir; Poland; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2001
Needlestick transmission of hepatitis C.
    JAMA, 2002, May-08, Volume: 287, Issue:18

    Topics: Accidents, Occupational; Acute Disease; Adult; Anti-HIV Agents; Antiviral Agents; Asthenia; Exanthema; Hepacivirus; Hepatitis C; Hepatitis C Antibodies; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Interferon alpha-2; Interferon-alpha; Internship and Residency; Lamivudine; Needlestick Injuries; Nelfinavir; Occupational Exposure; Physicians; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Viremia; Zidovudine

2002
Delayed recovery of effector memory CD4+ T cells by highly active antiretroviral therapy in a patient with HIV-1 infection.
    The Tohoku journal of experimental medicine, 2002, Volume: 196, Issue:3

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Immunologic Memory; Lamivudine; Lymphocyte Count; Male; Nelfinavir; Time Factors; Zidovudine

2002
Normalization of liver enzymes in an HIV-hepatitis C virus-co-infected patient after potent antiretroviral therapy.
    AIDS (London, England), 2002, May-24, Volume: 16, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Alanine Transaminase; Alkynes; Anti-HIV Agents; Aspartate Aminotransferases; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Female; Hepatitis C; Humans; Lamivudine; Liver; Oxazines; RNA, Viral; Zidovudine

2002
Determination of zidovudine/lamivudine/nevirapine in human plasma using ion-pair HPLC.
    Journal of pharmaceutical and biomedical analysis, 2002, Jun-01, Volume: 28, Issue:5

    Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamivudine; Nevirapine; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Zidovudine

2002
Pressure of zidovudine accelerates the reversion of lamivudine resistance-conferring M184V mutation in the reverse transcriptase of human immunodeficiency virus type 1.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:7

    Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Virus Replication; Zidovudine

2002
Transmission of drug-resistant HIV after an occupational exposure despite postexposure prophylaxis with a combination drug regimen.
    Infection control and hospital epidemiology, 2002, Volume: 23, Issue:6

    Topics: Adult; Anti-HIV Agents; Health Personnel; HIV; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Needlestick Injuries; Occupational Exposure; Treatment Failure; Zidovudine

2002
Human immunodeficiency virus 1 strains resistant to nucleoside inhibitors of reverse transcriptase in isolates from the Czech Republic as monitored by line probe assay and nucleotide sequencing.
    Acta virologica, 2001, Volume: 45, Issue:5-6

    Topics: Base Sequence; Codon; Czech Republic; Didanosine; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Probe Techniques; Molecular Sequence Data; Mutation; Phylogeny; Prevalence; Reverse Transcriptase Inhibitors; Sequence Analysis, DNA; Zalcitabine; Zidovudine

2001
Counterfit drugs: check Combivir, Serostim, Epogen.
    AIDS treatment news, 2002, May-31, Issue:380

    Topics: Crime; Drug Combinations; Drug Labeling; Epoetin Alfa; Erythropoietin; Growth Hormone; Human Growth Hormone; Lamivudine; Recombinant Proteins; United States; United States Food and Drug Administration; Zidovudine

2002
A case of flare syndrome.
    Le infezioni in medicina, 2001, Volume: 9, Issue:3

    Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Indinavir; Lamivudine; Male; Organophosphonates; Organophosphorus Compounds; Zidovudine

2001
Anti-HIV agents. Trizivir--three drugs in one pill.
    TreatmentUpdate, 2000, Volume: 12, Issue:1

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Zidovudine

2000
Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11.
    The Biochemical journal, 2002, Nov-15, Volume: 368, Issue:Pt 1

    Topics: Anti-HIV Agents; ATP-Binding Cassette Transporters; Biological Transport; Deoxycytidine Kinase; Drug Resistance, Multiple; HIV; Humans; Lamivudine; Multidrug Resistance-Associated Proteins; Nucleosides; T-Lymphocytes; Tumor Cells, Cultured; Zidovudine

2002
Immunophenotypic analyses of CD34(+) cell subsets in bone marrow from HIV-infected patients during highly- active antiretroviral therapy.
    European journal of clinical investigation, 2002, Volume: 32, Issue:7

    Topics: Adult; Antigens, CD34; Antiretroviral Therapy, Highly Active; beta 2-Microglobulin; Bone Marrow Cells; Case-Control Studies; Female; Flow Cytometry; HIV Infections; HIV Protease Inhibitors; Humans; Immunoglobulin G; Immunophenotyping; Indinavir; Lamivudine; Leukocyte Count; Male; Middle Aged; Stavudine; T-Lymphocyte Subsets; Zidovudine

2002
Antiretroviral rounds. Personal and public consequences.
    AIDS clinical care, 2000, Volume: 12, Issue:1

    Topics: Adult; Alcohol Drinking; Candidiasis, Oral; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Pneumonia, Bacterial; Sexual Partners; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Zidovudine

2000
"Trizivir" approved: three existing drugs in one.
    AIDS treatment news, 2000, Nov-17, Issue:355

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Approval; Drug Combinations; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine

2000
Geotrichum proctitis after HIV postexposure prophylaxis.
    AIDS (London, England), 2002, Aug-16, Volume: 16, Issue:12

    Topics: Drug Therapy, Combination; Female; Geotrichosis; HIV Infections; Humans; Lamivudine; Middle Aged; Proctitis; Reverse Transcriptase Inhibitors; Zidovudine

2002
HIV-1 infection in women.
    The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2000, Volume: 12, Issue:4

    Topics: CD4 Lymphocyte Count; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Male; Sexual Behavior; Sexually Transmitted Diseases; Thailand; Viral Load; Zidovudine

2000
New drugs.
    The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2001, Volume: 13, Issue:1

    Topics: Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Approval; Drug Combinations; Humans; Lamivudine; Lopinavir; Pyrimidinones; Ritonavir; Zidovudine

2001
Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies.
    Journal of virology, 2002, Volume: 76, Issue:18

    Topics: Animals; Anti-HIV Agents; COS Cells; Dose-Response Relationship, Drug; Drug Resistance, Viral; Genetic Vectors; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Thymidine; Virus Replication; Zidovudine

2002
Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine.
    Carcinogenesis, 2002, Volume: 23, Issue:9

    Topics: Animals; Anti-HIV Agents; Bone Marrow; Bromodeoxyuridine; Drug Interactions; Drug Resistance, Neoplasm; Erythrocytes; Female; Gene Frequency; Hypoxanthine Phosphoribosyltransferase; Lamivudine; Loss of Heterozygosity; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronuclei, Chromosome-Defective; Mutation; Thymidine Kinase; Zidovudine

2002
Prevalence of G333D/E in naive and pretreated HIV-infected patients.
    AIDS research and human retroviruses, 2002, Aug-10, Volume: 18, Issue:12

    Topics: Amino Acid Sequence; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

2002
Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
    Journal of virology, 2002, Volume: 76, Issue:19

    Topics: Adenosine Triphosphate; Anti-HIV Agents; Codon; Crystallization; Drug Resistance, Viral; HIV Reverse Transcriptase; Lamivudine; Mutation; Protein Conformation; Zidovudine

2002
[Cytomegalovirus retinitis after highly active antiretroviral therapy: a case report].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Didanosine; Ganciclovir; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Retinal Hemorrhage; Reverse Transcriptase Inhibitors; Risk; Saquinavir; Stavudine; Substance Abuse, Intravenous; Zidovudine

2002
Highlights of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).
    The Body positive, 2002, Volume: 15, Issue:3

    Topics: Adenine; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Drug Therapy; Epoetin Alfa; Erythropoietin; Hepatitis C; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Saquinavir; Tenofovir; Zidovudine

2002
Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach.
    Antiviral chemistry & chemotherapy, 2002, Volume: 13, Issue:2

    Topics: Anti-HIV Agents; Binding Sites; Dioxolanes; Drug Resistance; Guanosine; HIV-1; Lamivudine; Models, Molecular; Mutation, Missense; Protein Binding; Purine Nucleosides; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Zidovudine

2002
Development of a pharmacodynamic model for HIV treatment with nucleoside reverse transcriptase and protease inhibitors.
    Antiviral research, 2002, Volume: 56, Issue:2

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Statistical; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Viral Load; Zidovudine

2002
Cost price drugs for developing countries are found in Belgian pharmacies.
    BMJ (Clinical research ed.), 2002, Oct-12, Volume: 325, Issue:7368

    Topics: Anti-HIV Agents; Belgium; Crime; Developing Countries; Drug Combinations; Humans; Lamivudine; Pharmacies; Zidovudine

2002
Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors.
    Journal of molecular biology, 2002, Oct-18, Volume: 323, Issue:2

    Topics: Amino Acid Sequence; Deoxycytidine Monophosphate; Diphosphates; DNA; DNA Primers; DNA Replication; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; Humans; Lamivudine; Molecular Sequence Data; Recombinant Proteins; Reverse Transcriptase Inhibitors; Sequence Alignment; Thymidine Monophosphate; Zalcitabine; Zidovudine

2002
Metabolic activation of nucleoside and nucleotide reverse transcriptase inhibitors in dendritic and Langerhans cells.
    AIDS (London, England), 2002, Nov-08, Volume: 16, Issue:16

    Topics: Adenine; Anti-HIV Agents; Cell Line; Cells, Cultured; Dendritic Cells; Humans; Lamivudine; Langerhans Cells; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; T-Lymphocytes; Tenofovir; Zidovudine

2002
[Factors predicting lack of adherence to highly active antiretroviral treatment].
    Enfermedades infecciosas y microbiologia clinica, 2002, Volume: 20, Issue:10

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Data Collection; Drug Combinations; Drug Utilization Review; HIV Infections; Humans; Lamivudine; Outpatient Clinics, Hospital; Patient Compliance; Patient Dropouts; Registries; Sensitivity and Specificity; Spain; Treatment Refusal; Zidovudine

2002
Phenotypic and genotypic analysis of biologically cloned human immunodeficiency virus type 1 isolates from patients treated with zidovudine and lamivudine.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:12

    Topics: Clone Cells; Drug Resistance, Viral; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Zidovudine

2002
Mean cell volume (MCV) changes in HIV-positive patients taking nucleoside reverse transcriptase inhibitors (NRTIs): a surrogate marker for adherence.
    International journal of STD & AIDS, 2002, Volume: 13, Issue:11

    Topics: Biomarkers; Erythrocyte Indices; HIV Infections; Humans; Lamivudine; Patient Compliance; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine

2002
High prevalence of genotypic resistance to nucleoside reverse transcriptase inhibitors among therapy-naive individuals from the Warsaw cohort.
    Infection, 2002, Volume: 30, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Cohort Studies; Drug Resistance, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

2002
Impact of stavudine phenotype and thymidine analogues mutations on viral response to stavudine plus lamivudine in ALTIS 2 ANRS trial.
    Antiviral therapy, 2002, Volume: 7, Issue:3

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Lamivudine; Male; Middle Aged; Molecular Sequence Data; Mutation; Phenotype; RNA, Viral; Stavudine; Zidovudine

2002
Therapeutic responses to AZT + 3TC + EFV in advanced antiretroviral naive HIV type 1-infected Ugandan patients.
    AIDS research and human retroviruses, 2002, Nov-01, Volume: 18, Issue:16

    Topics: Adult; Alkynes; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Oxazines; Patient Compliance; Reverse Transcriptase Inhibitors; Uganda; Viral Load; Zidovudine

2002
Effect of co-formulated zidovudine, lamivudine and abacavir (Trizivir) on antiretroviral-naive patients presenting with advanced HIV-1 infection.
    AIDS (London, England), 2003, Feb-14, Volume: 17, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; Viral Load; Zidovudine

2003
Indirect hyperbilirubinemia with indinavir.
    The Journal of the Association of Physicians of India, 2002, Volume: 50

    Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Hyperbilirubinemia; India; Indinavir; Lamivudine; Liver Function Tests; Needlestick Injuries; Prognosis; Risk Assessment; Severity of Illness Index; Zidovudine

2002
Estimating the length of the first antiretroviral therapy regiment durability in São Paulo, Brazil.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2002, Volume: 6, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brazil; Cohort Studies; Drug Administration Schedule; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Compliance; Retrospective Studies; Time Factors; Zidovudine

2002
Multiple relapses of human cytomegalovirus retinitis during HAART in an AIDS patient with reconstitution of CD4+ T cell count in the absence of HCMV-specific CD4+ T cell response.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 26, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cytomegalovirus Retinitis; Didanosine; Follow-Up Studies; Ganciclovir; HIV Protease Inhibitors; Humans; Lamivudine; Lymphocyte Activation; Male; Nevirapine; Recurrence; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2003
HIV--a personal perspective.
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2000, Volume: 55, Issue:12

    Topics: Anti-HIV Agents; HIV Infections; Humans; Lamivudine; Needlestick Injuries; Zidovudine

2000
Preventing HIV transmission.
    Lancet (London, England), 2003, Mar-08, Volume: 361, Issue:9360

    Topics: Anti-HIV Agents; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Zidovudine

2003
FDA notifications. Product tampering labels Ziagen as Combivir.
    AIDS alert, 2002, Volume: 17, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Dideoxynucleosides; Drug Combinations; Drug Labeling; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine

2002
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: Acquired Immunodeficiency Syndrome; Cytidine Triphosphate; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Dideoxynucleotides; Dioxolanes; DNA, Viral; Drug Resistance, Viral; Guanosine; Guanosine Triphosphate; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine

2003
Negligence. Liver transplant patient too late to sue Viramune maker.
    AIDS policy & law, 2003, Mar-28, Volume: 18, Issue:6

    Topics: Drug Combinations; Drug Industry; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Liver Failure; Liver Transplantation; Malpractice; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine

2003
Abacavir arm stopped in clinical trial.
    AIDS treatment news, 2003, Apr-04, Issue:390

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Viral Load; Zidovudine

2003
AIDS drug in halted trial less effective as monotherapy.
    The AIDS reader, 2003, Volume: 13, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Humans; Lamivudine; Oxazines; Viral Load; Zidovudine

2003
Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.
    Journal of molecular biology, 2003, May-23, Volume: 329, Issue:1

    Topics: Amino Acid Sequence; Anti-HIV Agents; Baculoviridae; Binding Sites; DNA Polymerase gamma; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Electrophoretic Mobility Shift Assay; Humans; Lamivudine; Mitochondria; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Stavudine; Zalcitabine; Zidovudine

2003
[Measuring the HIV viral load with LCx (Abbott): importance for the therapeutic follow-up of 3 patients infected by type O HIV].
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2003, Volume: 10, Issue:2

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Oxazines; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; Stavudine; Viral Load; Viremia; Zidovudine

2003
Management of severely immunocompromised human immunodeficiency virus type 1-infected African orphans with structured treatment interruption: another kind of salvage therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Jun-01, Volume: 36, Issue:11

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Dideoxynucleosides; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Salvage Therapy; Zidovudine

2003
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
    Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:1

    Topics: Adenine; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Didanosine; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Transfection; Zalcitabine; Zidovudine

2003
Mutations E44D and V118I in the reverse transcriptase of HIV-1 play distinct mechanistic roles in dual resistance to AZT and 3TC.
    The Journal of biological chemistry, 2003, Sep-05, Volume: 278, Issue:36

    Topics: Adenosine Triphosphate; Anti-HIV Agents; Base Sequence; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Resistance, Viral; HIV Reverse Transcriptase; Inhibitory Concentration 50; Kinetics; Lamivudine; Molecular Sequence Data; Mutation; Phenotype; Time Factors; Zidovudine

2003
Selection of resistance mutations in pregnant women receiving zidovudine and lamivudine to prevent HIV perinatal transmission.
    AIDS (London, England), 2003, Jul-04, Volume: 17, Issue:10

    Topics: Anti-HIV Agents; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Pregnancy; Retrospective Studies; Zidovudine

2003
Trizivir trial halted.
    AIDS patient care and STDs, 2003, Volume: 17, Issue:5

    Topics: Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Zidovudine

2003
[Observational study on the efficacy of the application of two classical regimens of triple antiretroviral therapy].
    Anales de medicina interna (Madrid, Spain : 1984), 2003, Volume: 20, Issue:5

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Didanosine; Drug Evaluation; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2003
Sequential cutaneous drug reactions to protease inhibitors in the context of occupational post-exposure prophylaxis.
    AIDS (London, England), 2003, Jul-25, Volume: 17, Issue:11

    Topics: Adult; Drug Hypersensitivity; Female; Guideline Adherence; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Needlestick Injuries; Occupational Diseases; Occupational Exposure; Zidovudine

2003
[Opiates withdrawal syndrome after treatment with zidovudine + lamivudine + abcavir in patients with positivity for HIV and treated with methadone].
    Revista clinica espanola, 2003, Volume: 203, Issue:8

    Topics: Adult; Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Male; Methadone; Opioid-Related Disorders; Reverse Transcriptase Inhibitors; Substance Withdrawal Syndrome; Treatment Outcome; Zidovudine

2003
Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors.
    The Journal of infectious diseases, 2003, Aug-01, Volume: 188, Issue:3

    Topics: Adenine; Cell Line; Dideoxynucleosides; Human T-lymphotropic virus 1; Humans; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Virus Replication; Zalcitabine; Zidovudine

2003
Vertical transmission of HIV in Rio de Janeiro, Brazil.
    AIDS (London, England), 2003, Aug-15, Volume: 17, Issue:12

    Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; Brazil; Cohort Studies; Developing Countries; Female; HIV Infections; Humans; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Pregnancy; Pregnancy Complications, Infectious; Risk Factors; Zidovudine

2003
pol gene sequence variation in Swedish HIV-2 patients failing antiretroviral therapy.
    AIDS research and human retroviruses, 2003, Volume: 19, Issue:7

    Topics: Adolescent; Adult; Africa, Western; Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; Codon; Drug Resistance, Multiple, Viral; Evolution, Molecular; Female; Genes, pol; Genetic Variation; HIV Infections; HIV Protease Inhibitors; HIV-1; HIV-2; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Nelfinavir; Prospective Studies; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Sequence Alignment; Sequence Homology, Amino Acid; Sweden; Treatment Failure; Viremia; Zidovudine

2003
[Antiviral agents for reduction of mother-to-child transmission of HIV infection].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2003, Aug-14, Volume: 123, Issue:15

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Evidence-Based Medicine; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Zidovudine

2003
[Inhibitory effect of telomerase inhibitors combined with X-irradiation on bone marrow hematopoiesis in mice].
    Zhongguo shi yan xue ye xue za zhi, 2003, Volume: 11, Issue:4

    Topics: Animals; Bone Marrow; Enzyme Inhibitors; Female; Hematopoiesis; Lamivudine; Mice; Mice, Inbred BALB C; Telomerase; X-Rays; Zidovudine

2003
AIDS foundation seeks withdrawal of approval for HIV drug combination.
    The Lancet. Infectious diseases, 2003, Volume: 3, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Anti-HIV Agents; Clinical Trials as Topic; Dideoxynucleosides; Drug Approval; Drug Combinations; Foundations; Humans; Lamivudine; United States; United States Food and Drug Administration; Zidovudine

2003
[Hypersensitive reaction to abacavir or syphilitic hepatitis?].
    Presse medicale (Paris, France : 1983), 2003, Oct-11, Volume: 32, Issue:33

    Topics: Adult; Anti-HIV Agents; Chemical and Drug Induced Liver Injury; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Ethylenediamines; HIV Seropositivity; Humans; Lamivudine; Male; Syphilis; Zidovudine

2003
Studies of molecular mechanism of tenofovir against 3TC- and AZT-resistance mutant HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2003, Nov-17, Volume: 13, Issue:22

    Topics: Adenine; Amino Acid Sequence; Drug Resistance, Viral; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Mutagenesis, Site-Directed; Organophosphonates; Organophosphorus Compounds; Protein Conformation; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2003
Safety and efficacy of switching to alternative nucleoside analogues following symptomatic hyperlactatemia and lactic acidosis.
    AIDS (London, England), 2003, Nov-21, Volume: 17, Issue:17

    Topics: Acidosis, Lactic; Adult; Alanine Transaminase; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lactates; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Zidovudine

2003
Liquid chromatographic-mass spectrometric determination of the metabolism and disposition of the anti-retroviral nucleoside analogs zidovudine and lamivudine in C57BL/6N and B6C3F1 mice.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Dec-05, Volume: 798, Issue:1

    Topics: Animals; Area Under Curve; Chromatography, Liquid; Female; Fetus; Lamivudine; Mass Spectrometry; Mice; Mice, Inbred Strains; Reproducibility of Results; Reverse Transcriptase Inhibitors; Zidovudine

2003
AACTG A5095, Trizivir, and the role of all-nucleoside regimens: an editorial.
    The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2003, Volume: 15, Issue:4

    Topics: CD4 Lymphocyte Count; Clinical Trials as Topic; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2003
Abandon Trizivir when it's working well? A rebuttal.
    The Hopkins HIV report : a bimonthly newsletter for healthcare providers, 2003, Volume: 15, Issue:4

    Topics: Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2003
GSK and Boehringer agree to generic AIDS drugs deal.
    Lancet (London, England), 2003, Dec-20, Volume: 362, Issue:9401

    Topics: Acquired Immunodeficiency Syndrome; Africa South of the Sahara; Anti-Retroviral Agents; Commerce; Drug Industry; Drugs, Generic; Humans; Lamivudine; Legislation, Drug; South Africa; Zidovudine

2003
Treatment of primary HIV-1 infection with nonnucleoside reverse transcriptase inhibitor-based therapy is effective and well tolerated.
    HIV medicine, 2004, Volume: 5, Issue:1

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4-CD8 Ratio; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Flow Cytometry; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Activation; Lymphocyte Subsets; Male; Middle Aged; Oxazines; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2004
HIVNET 012 and Petra.
    Lancet (London, England), 2004, Jan-17, Volume: 363, Issue:9404

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine

2004
Comment: Reasons for early abacavir discontinuation in HIV-infected patients.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Treatment Refusal; Zidovudine

2004
Conference report - antiretroviral therapy update from the 9th European AIDS Conference.
    MedGenMed : Medscape general medicine, 2003, Dec-12, Volume: 5, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Age Factors; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Botswana; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; HIV Infections; Humans; Lamivudine; Middle Aged; Pulse Therapy, Drug; Reverse Transcriptase Inhibitors; Salvage Therapy; Viral Load; Zidovudine

2003
Efficacy and safety of ritonavir/indinavir 100/400 mg twice daily in combination with two nucleoside analogues in antiretroviral treatment-naive HIV-infected individuals.
    Antiviral therapy, 2003, Volume: 8, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Ritonavir; Stavudine; Zidovudine

2003
Antiretroviral therapy influences cellular susceptibility to apoptosis in vivo.
    Frontiers in bioscience : a journal and virtual library, 2004, Jan-01, Volume: 9

    Topics: Adult; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Apoptosis; Drug Combinations; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Zidovudine

2004
In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates.
    Arzneimittel-Forschung, 2004, Volume: 54, Issue:1

    Topics: Cells, Cultured; Dideoxynucleotides; Drug Resistance, Viral; Genotype; HIV; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Neutrophils; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Thymidine Monophosphate; Viral Plaque Assay; Zidovudine

2004
Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Mar-01, Volume: 38, Issue:5

    Topics: Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Interactions; Epilepsy, Complex Partial; HIV Infections; Humans; Lamivudine; Male; Valproic Acid; Zidovudine

2004
Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine.
    AIDS research and human retroviruses, 2004, Volume: 20, Issue:1

    Topics: Animals; Anti-HIV Agents; Brain; DNA, Mitochondrial; Erythrocebus patas; Female; Fetus; Lamivudine; Maternal-Fetal Exchange; Microscopy, Electron; Mitochondria; Muscle, Skeletal; Myocardium; Organ Specificity; Placenta; Pregnancy; Reverse Transcriptase Inhibitors; Zidovudine

2004
[Ensuring high adherence. Clever combination assures therapeutic success].
    MMW Fortschritte der Medizin, 2003, Apr-28, Volume: 145 Spec No 1

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Humans; Lamivudine; Oxazines; Patient Compliance; Randomized Controlled Trials as Topic; Treatment Outcome; Zidovudine

2003
[Long-term tolerance. Preventing lipoatrophy].
    MMW Fortschritte der Medizin, 2003, Apr-28, Volume: 145 Spec No 1

    Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Dideoxynucleosides; DNA, Mitochondrial; Drug Combinations; HIV-Associated Lipodystrophy Syndrome; Humans; Lamivudine; Long-Term Care; Risk Factors; Stavudine; Zidovudine

2003
Purifying selection masks the mutational flexibility of HIV-1 reverse transcriptase.
    The Journal of biological chemistry, 2004, Jun-18, Volume: 279, Issue:25

    Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Anti-Retroviral Agents; Cell Line; Cloning, Molecular; Conserved Sequence; DNA Mutational Analysis; Genetic Techniques; Genetic Variation; HeLa Cells; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Virus Replication; Zidovudine

2004
Behavioral impact, acceptability, and HIV incidence among homosexual men with access to postexposure chemoprophylaxis for HIV.
    Journal of acquired immune deficiency syndromes (1999), 2004, Apr-15, Volume: 35, Issue:5

    Topics: Adult; Anti-HIV Agents; Brazil; Chemoprevention; Cohort Studies; HIV Infections; HIV Seropositivity; Homosexuality, Male; Humans; Lamivudine; Male; Patient Acceptance of Health Care; Sexual Behavior; Surveys and Questionnaires; Zidovudine

2004
Comparison of generic zidovudine + lamivudine (Cipla, Duovir) and the GlaxoSmithKline brand (Combivir) tablets.
    Journal of acquired immune deficiency syndromes (1999), 2004, Apr-15, Volume: 35, Issue:5

    Topics: Chromatography, High Pressure Liquid; Costs and Cost Analysis; Drug Combinations; Drugs, Generic; HIV Infections; Humans; Lamivudine; Tablets; Zidovudine

2004
Derivative-differential UV spectrophotometry and compensation technique for the simultaneous determination of zidovudine and lamivudine in human serum.
    Die Pharmazie, 2004, Volume: 59, Issue:2

    Topics: Adult; Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Drug Combinations; Humans; Lamivudine; Male; Reference Standards; Spectrophotometry, Ultraviolet; Tablets; Zidovudine

2004
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir.
    AIDS (London, England), 2004, Apr-30, Volume: 18, Issue:7

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Mitochondrial; Drug Combinations; Female; Fetal Blood; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Maternal-Fetal Exchange; Microscopy, Electron; Mitochondria; Pilot Projects; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Umbilical Cord; Zidovudine

2004
Buffalo hump: what the experts suggest.
    AIDS clinical care, 2004, Volume: 16, Issue:3

    Topics: Adult; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Lipodystrophy; Male; Reverse Transcriptase Inhibitors; Zidovudine

2004
Lamivudine 300 mg in HIV infection: dose change. Once-a-day dosing.
    Prescrire international, 2004, Volume: 13, Issue:70

    Topics: Adult; Child; Drug Therapy, Combination; France; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Protease Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2004
Hemophagocytic syndrome as a presenting sign of transformation of smoldering to acute adult T-cell leukemia/lymphoma: efficacy of anti-retroviral and interferon therapy.
    American journal of hematology, 2004, Volume: 76, Issue:2

    Topics: Antineoplastic Agents; Antiviral Agents; Drug Therapy, Combination; Female; Histiocytosis; Humans; Interferon-alpha; Lamivudine; Leukemia-Lymphoma, Adult T-Cell; Middle Aged; Zidovudine

2004
[Antiretroviral therapy of acute HIV-infection].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Combinations; Female; HIV Infections; HIV Seropositivity; Humans; Lamivudine; Lymphocyte Count; Male; Nevirapine; Viral Load; Zidovudine

2004
Benefits of a rapid HIV test for evaluation of the source patient after occupational exposure of healthcare workers.
    The Journal of hospital infection, 2004, Volume: 57, Issue:2

    Topics: AIDS Serodiagnosis; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood-Borne Pathogens; Chemoprevention; Diagnostic Tests, Routine; Health Personnel; HIV Infections; Humans; Immunoenzyme Techniques; Infectious Disease Transmission, Patient-to-Professional; Italy; Lamivudine; Occupational Exposure; Pilot Projects; Zidovudine

2004
WHO pulls two generic AIDS drugs from approved list.
    BMJ (Clinical research ed.), 2004, Jun-26, Volume: 328, Issue:7455

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Approval; Drugs, Generic; Formularies as Topic; Humans; Lamivudine; Therapeutic Equivalency; World Health Organization; Zidovudine

2004
Mitochondrial damage revealed by morphometric and semiquantitative analysis of mouse pup cardiomyocytes following in utero and postnatal exposure to zidovudine and lamivudine.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:2

    Topics: Animals; Animals, Newborn; Anti-HIV Agents; Female; Lamivudine; Male; Mice; Microscopy, Electron; Mitochondria, Heart; Myocytes, Cardiac; Pregnancy; Zidovudine

2004
Nucleoside analogue use before and during highly active antiretroviral therapy and virus load rebound.
    The Journal of infectious diseases, 2004, Aug-15, Volume: 190, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Australia; Cohort Studies; Didanosine; Drug Administration Schedule; Europe; Female; HIV Infections; Humans; Lamivudine; Male; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Stavudine; Time Factors; Viral Load; Zidovudine

2004
Zidovudine, lamivudine, and abacavir have different effects on resting cells infected with human immunodeficiency virus in vitro.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:8

    Topics: Anti-HIV Agents; Cells, Cultured; Dideoxynucleosides; Drug Evaluation, Preclinical; HIV Core Protein p24; HIV Infections; Humans; Immunotoxins; Lamivudine; Phytohemagglutinins; Receptors, Interleukin-2; Reverse Transcriptase Inhibitors; Zidovudine

2004
Triple-nucleoside regimens versus efavirenz.
    The New England journal of medicine, 2004, Aug-12, Volume: 351, Issue:7

    Topics: Alkynes; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Oxazines; Research Design; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2004
Triple-nucleoside regimens versus efavirenz.
    The New England journal of medicine, 2004, Aug-12, Volume: 351, Issue:7

    Topics: Alkynes; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Oxazines; Patient Compliance; Reverse Transcriptase Inhibitors; Zidovudine

2004
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.
    Cardiovascular toxicology, 2004, Volume: 4, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Anti-HIV Agents; Body Weight; Cardiomyopathies; DNA, Mitochondrial; Drug Interactions; Electrocardiography; Electron Transport Complex IV; Female; Lamivudine; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mutation; Myocardium; Organ Size; Pilot Projects; Pregnancy; Sex Factors; Zidovudine

2004
Simultaneous determination of zidovudine and lamivudine from rat plasma, amniotic fluid and tissues by HPLC.
    Biomedical chromatography : BMC, 2004, Volume: 18, Issue:9

    Topics: Amniotic Fluid; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Female; Fetus; Half-Life; Lamivudine; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Tissue Distribution; Zidovudine

2004
Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy.
    American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:3

    Topics: Abnormalities, Drug-Induced; Anti-Retroviral Agents; Female; Gestational Age; Humans; Lamivudine; Maternal-Fetal Exchange; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Prospective Studies; Risk Factors; Stavudine; Zidovudine

2004
Perinatal HIV research unit clarifies nevirapine resistance and transmission issues.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2004, Volume: 94, Issue:9

    Topics: Anti-HIV Agents; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Zidovudine

2004
Tenofovir: new indication. For first-line antiretroviral therapy: wait and see.
    Prescrire international, 2004, Volume: 13, Issue:73

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Controlled Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Zidovudine

2004
Antiretroviral treatment. HIV infection in adults: better-defined first-line treatment.
    Prescrire international, 2004, Volume: 13, Issue:72

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Dideoxynucleosides; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Oligopeptides; Organophosphonates; Oxazines; Pregnancy; Pyrimidinones; Ritonavir; Stavudine; Sulfonamides; Treatment Outcome; Viral Load; Zidovudine

2004
[Simplified treatments for HIV infection].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:10

    Topics: Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Randomized Controlled Trials as Topic; Switzerland; Time Factors; Treatment Outcome; Zidovudine

2004
Effect of concurrent zidovudine use on the resistance pathway selected by abacavir-containing regimens.
    HIV medicine, 2004, Volume: 5, Issue:6

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Resistance, Viral; Drug Therapy, Combination; Genes, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Phenotype; Point Mutation; Retrospective Studies; Reverse Transcriptase Inhibitors; Zidovudine

2004
Pilot studies of single and combination antiretroviral therapy in patients with primary biliary cirrhosis.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:12

    Topics: Adult; Aged; Analysis of Variance; Drug Combinations; Female; Humans; Lamivudine; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Pilot Projects; Retroviridae Infections; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine

2004
Proof of principal studies to assess the role of the human betaretrovirus in patients with primary biliary cirrhosis.
    The American journal of gastroenterology, 2004, Volume: 99, Issue:12

    Topics: Autoimmune Diseases; Drug Combinations; Humans; Lamivudine; Liver Cirrhosis, Biliary; Retroviridae Infections; Zidovudine

2004
The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
    AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16

    Topics: 3T3-L1 Cells; Adenine; Adipocytes; Animals; Apoptosis; Cell Differentiation; Didanosine; Dideoxynucleosides; HIV-1; HIV-Associated Lipodystrophy Syndrome; Lamivudine; Lipid Metabolism; Mice; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Zidovudine

2004
Long-term efficacy after switch from protease inhibitor-containing highly active antiretroviral therapy to abacavir, lamivudine, and zidovudine.
    AIDS (London, England), 2004, Nov-05, Volume: 18, Issue:16

    Topics: Adult; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Time Factors; Treatment Failure; Zidovudine

2004
Response to the comparison of generic zidovudine plus lamivudine (Cipla, Duovir) and the GlaxoSmithKline brand (Combivir) tablets.
    Journal of acquired immune deficiency syndromes (1999), 2004, Dec-01, Volume: 37, Issue:4

    Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Generic; HIV Infections; Humans; Lamivudine; Tablets; Zidovudine

2004
Fatal inflammatory AIDS-associated PML with high CD4 counts on HAART: a new clinical entity?
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; CD4 Lymphocyte Count; Cidofovir; Cytosine; Dideoxynucleosides; Encephalitis; False Negative Reactions; Fatal Outcome; Humans; Immunocompromised Host; Indinavir; JC Virus; Lamivudine; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Male; Organophosphonates; Substance Abuse, Intravenous; Time Factors; Virus Activation; Zidovudine

2004
Emergence of antiretroviral resistance in HIV-positive women receiving combination antiretroviral therapy in pregnancy.
    AIDS (London, England), 2005, Jan-03, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Base Sequence; Cohort Studies; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Reverse Transcriptase Inhibitors; RNA, Viral; Zidovudine

2005
Low rate of treatment failure on antiretroviral therapy with tenofovir, lamivudine and zidovudine.
    AIDS (London, England), 2005, Jan-03, Volume: 19, Issue:1

    Topics: Adenine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Treatment Failure; Zidovudine

2005
Effects of prenatal exposure to Zidovudine and Lamivudine on brainstem auditory evoked potentials in infants from HIV-infected women.
    Proceedings of the Western Pharmacology Society, 2004, Volume: 47

    Topics: Adult; Anti-HIV Agents; Apgar Score; Evoked Potentials, Auditory, Brain Stem; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Zidovudine

2004
Two AIDS medicines back on WHO prequalification list.
    Releve epidemiologique hebdomadaire, 2004, Dec-10, Volume: 79, Issue:50

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Approval; Drugs, Generic; Humans; Lamivudine; Therapeutic Equivalency; World Health Organization; Zidovudine

2004
[Simplification to lamivudine, zidovudine, and abacavir therapy: impact on adherence, clinical outcome, and economic issues].
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2004, Volume: 28, Issue:6 Suppl 1

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Costs and Cost Analysis; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Patient Compliance; Retrospective Studies; Zidovudine

2004
Simultaneous determination of the HIV nucleoside analogue reverse transcriptase inhibitors lamivudine, didanosine, stavudine, zidovudine and abacavir in human plasma by reversed phase high performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Feb-25, Volume: 816, Issue:1-2

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Drug Stability; HIV; HIV Infections; Humans; Lamivudine; Quality Control; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine

2005
Inhibitory drug levels found in breast milk.
    AIDS patient care and STDs, 2004, Volume: 18, Issue:12

    Topics: Anti-Retroviral Agents; Female; HIV Infections; Humans; Infant; Lamivudine; Milk, Human; Nevirapine; Zidovudine

2004
HIV/AIDS following sexual assault in Jamaican children and adolescents: a case for HIV post-exposure prophylaxis.
    The West Indian medical journal, 2004, Volume: 53, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; Chemoprevention; Child; Child Abuse, Sexual; Drug Therapy, Combination; Female; HIV Infections; Humans; Jamaica; Lamivudine; Male; Rape; Risk Factors; Zidovudine

2004
Simultaneous determination of zidovudine and lamivudine from rat tissues by liquid chromatography/tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2005, Volume: 19, Issue:4

    Topics: Amniotic Fluid; Animals; Anti-HIV Agents; Drug Therapy, Combination; Female; Fetus; Injections, Intravenous; Lamivudine; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution; Zidovudine

2005
AIDS treatment. A step toward cheaper anti-HIV therapy.
    Science (New York, N.Y.), 2005, Feb-04, Volume: 307, Issue:5710

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Developing Countries; Drug Approval; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Humans; Lamivudine; Nevirapine; United States; United States Food and Drug Administration; World Health Organization; Zidovudine

2005
Top stories of 2004. ACTG 5095: efavirenz beats AZT + 3TC + abacavir.
    AIDS clinical care, 2005, Volume: 17, Issue:1

    Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Humans; Lamivudine; Oxazines; Viral Load; Zidovudine

2005
Meeting notes from ICAAC. Tenofovir + emtricitabine vs. AZT + 3TC.
    AIDS clinical care, 2005, Volume: 17, Issue:1

    Topics: Adenine; CD4 Lymphocyte Count; Deoxycytidine; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Zidovudine

2005
Meeting notes from ICAAC. NRTI-only regimens: making a comeback?
    AIDS clinical care, 2005, Volume: 17, Issue:1

    Topics: Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Humans; Lamivudine; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

2005
Field efficacy of zidovudine, lamivudine and single-dose nevirapine to prevent peripartum HIV transmission.
    AIDS (London, England), 2005, Feb-18, Volume: 19, Issue:3

    Topics: Adult; Anti-HIV Agents; Cote d'Ivoire; Developing Countries; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2005
Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells.
    Mutagenesis, 2005, Volume: 20, Issue:2

    Topics: Anti-HIV Agents; Base Sequence; Cell Cycle; DNA; DNA Adducts; Gene Expression; HeLa Cells; Humans; Lamivudine; Mutagens; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; S Phase; Zidovudine

2005
Postexposure prophylaxis after sexual assaults: a prospective cohort study.
    Sexually transmitted diseases, 2005, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Brazil; Child; Child, Preschool; Cohort Studies; Drug Administration Schedule; Female; HIV Infections; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Compliance; Prospective Studies; Rape; Sexually Transmitted Diseases; Zidovudine

2005
Rapid viral load suppression following generic highly active antiretroviral therapy in Southern Indian HIV-infected patients.
    AIDS (London, England), 2005, Mar-24, Volume: 19, Issue:6

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drugs, Generic; Female; HIV Infections; HIV-1; Humans; India; Lamivudine; Male; Middle Aged; Oxazines; Prospective Studies; Tablets; Treatment Outcome; Viral Load; Zidovudine

2005
[Meningeal cryptococcosis as a sign of immune reconstitution syndrome].
    Enfermedades infecciosas y microbiologia clinica, 2005, Volume: 23, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Fluconazole; Flucytosine; HIV Infections; Humans; Immunologic Memory; Lamivudine; Lopinavir; Male; Meningitis, Cryptococcal; Pyrimidinones; Recurrence; Ritonavir; Syndrome; T-Lymphocyte Subsets; Zidovudine

2005
Copackaged drug regimen approved for PEPFAR.
    AIDS alert, 2005, Volume: 20, Issue:4

    Topics: Adult; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine

2005
Highly active antiretroviral therapy and human immunodeficiency virus encephalitis.
    Annals of neurology, 2005, Volume: 57, Issue:6

    Topics: AIDS Dementia Complex; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Brain; Disease Models, Animal; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Mice; Mice, SCID; Monocytes; Viral Load; Zidovudine

2005
Switching from protease inhibitors to a single-class regimen of abacavir/lamivudine/zidovudine plus tenofovir in patients with HIV load suppression.
    AIDS (London, England), 2005, May-20, Volume: 19, Issue:8

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Zidovudine

2005
The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV post-exposure prophylaxis.
    HIV medicine, 2005, Volume: 6, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Chi-Square Distribution; HIV Infections; Humans; Lamivudine; Male; Nelfinavir; Organophosphonates; Reverse Transcriptase Inhibitors; Risk Assessment; Risk-Taking; Stavudine; Tenofovir; Zidovudine

2005
Recurrence of post-traumatic stress disorder and antiretrovirals.
    Scandinavian journal of infectious diseases, 2005, Volume: 37, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4-Positive T-Lymphocytes; Cyclopropanes; Female; HIV Infections; HIV-1; Humans; Lamivudine; Oxazines; Recurrence; RNA, Viral; Stress Disorders, Post-Traumatic; Viral Load; Zidovudine

2005
In vitro anti-HIV potency of stampidine alone and in combination with standard anti-HIV drugs.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:4

    Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Combinations; Drug Interactions; HIV-1; Humans; Lamivudine; Least-Squares Analysis; Models, Theoretical; Nelfinavir; Nevirapine; Phenotype; Stavudine; Thymidine Monophosphate; Virus Replication; Zidovudine

2005
Adherence to trizivir and tenofovir as a simplified salvage regimen is associated with suppression of viraemia and a decreased cholesterol.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cholesterol; Dideoxynucleosides; Drug Combinations; Erythrocyte Indices; Humans; Lamivudine; Organophosphonates; Patient Compliance; Salvage Therapy; Tenofovir; Viral Load; Viremia; Zidovudine

2005
Prospective study on the prevention of vertical transmission of HIV in Campo Grande, Mato Grosso do Sul, Brazil, from 1996 to 2001.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2005, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Brazil; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Risk Factors; Viral Load; Zidovudine

2005
Effect of antiretroviral drugs on maternal CD4 lymphocyte counts, HIV-1 RNA levels, and anthropometric parameters of their neonates.
    Clinics (Sao Paulo, Brazil), 2005, Volume: 60, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Birth Weight; Case-Control Studies; CD4 Lymphocyte Count; Female; Fetal Development; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; RNA, Viral; Zidovudine

2005
Simultaneous determination of HIV-protease inhibitors lamivudine and zidovudine in pharmaceutical formulations by micellar electrokinetic chromatography.
    Journal of pharmaceutical and biomedical analysis, 2005, Sep-15, Volume: 39, Issue:3-4

    Topics: 4-Aminobenzoic Acid; Borates; Boric Acids; Buffers; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis; HIV Protease Inhibitors; Hydrogen-Ion Concentration; Kinetics; Lamivudine; Micelles; Models, Chemical; Pharmaceutical Preparations; Pressure; Reproducibility of Results; Sodium Dodecyl Sulfate; Solvents; Time Factors; Zidovudine

2005
Lack of resistant mutation development after receiving short-course zidovudine plus lamivudine to prevent mother-to-child transmission.
    AIDS (London, England), 2005, Jul-22, Volume: 19, Issue:11

    Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2005
Genital HIV-1 viral load is correlated with blood plasma HIV-1 viral load in Brazilian women and is reduced by antiretroviral therapy.
    The Journal of infection, 2006, Volume: 52, Issue:4

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Brazil; Cervix Uteri; Cross-Sectional Studies; Cyclopropanes; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Nelfinavir; Prevalence; Time Factors; Vagina; Viral Load; Zidovudine

2006
Antiretroviral therapy--alternative uses.
    Sexually transmitted infections, 2005, Volume: 81, Issue:4

    Topics: Anti-Retroviral Agents; Breast; Cosmetic Techniques; Drug Combinations; Drug Resistance, Viral; Female; HIV Infections; Humans; Lamivudine; Zidovudine

2005
The effect of long-term storage on measured plasma lactate concentrations and prospective lactate results from a multicenter trial of antiretroviral therapy.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:9

    Topics: Acidosis, Lactic; Anti-HIV Agents; Blood Preservation; Blood Specimen Collection; Didanosine; HIV Infections; Humans; Lactates; Lamivudine; Multicenter Studies as Topic; Oxalates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Sodium Fluoride; Specimen Handling; Stavudine; Time Factors; Zidovudine

2005
Adherence to combined Lamivudine + Zidovudine versus individual components: a community-based retrospective medicaid claims analysis.
    AIDS care, 2005, Volume: 17, Issue:8

    Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Epidemiologic Methods; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Medicaid; Middle Aged; Patient Compliance; Zidovudine

2005
Case records of the Massachusetts General Hospital. Case 32-2005. A 34-year-old HIV-positive woman who desired to become pregnant.
    The New England journal of medicine, 2005, Oct-20, Volume: 353, Issue:16

    Topics: Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Cesarean Section; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Seropositivity; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Papillomaviridae; Papillomavirus Infections; Pregnancy; Pregnancy Complications, Infectious; Prenatal Care; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Uterine Cervicitis; Viral Load; Zidovudine

2005
Life-threatening maternal and fetal macrocytic anemia from antiretroviral therapy.
    Obstetrics and gynecology, 2005, Volume: 106, Issue:5 Pt 2

    Topics: Adult; Anemia, Macrocytic; Anti-HIV Agents; Cesarean Section; Drug Therapy, Combination; Female; Fetal Diseases; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Complications, Infectious; Pregnancy Outcome; Viral Load; Zidovudine

2005
Triple nucleoside reverse transcriptase inhibitor- vs. nonnucleoside reverse transcriptase inhibitor-containing regimens as first-line therapy: efficacy and durability in a prospective cohort of French HIV-infected patients.
    HIV medicine, 2005, Volume: 6, Issue:6

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Oxazines; Prospective Studies; Reverse Transcriptase Inhibitors; Treatment Failure; Treatment Outcome; Viral Load; Zidovudine

2005
Mass needle stick injury in children from the Western cape.
    Journal of tropical pediatrics, 2006, Volume: 52, Issue:3

    Topics: Adolescent; Anti-HIV Agents; Child; Child, Preschool; Communicable Disease Control; Environmental Exposure; Hepatitis B; Hepatitis B Vaccines; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Medical Waste; Needlestick Injuries; South Africa; Treatment Outcome; Zidovudine

2006
Hypertriglyceridemia and hypercholesterolemia in human immunodeficiency virus-1-infected children treated with protease inhibitors.
    Archives of medical research, 2006, Volume: 37, Issue:1

    Topics: Adolescent; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Hypertriglyceridemia; Infant; Lamivudine; Male; Ritonavir; Saquinavir; Zidovudine

2006
Bleomycin has antiviral properties against drug-resistant HIV strains and sensitises virus to currently used antiviral agents.
    International journal of antimicrobial agents, 2006, Volume: 27, Issue:1

    Topics: Anti-HIV Agents; Bleomycin; Cells, Cultured; Drug Resistance, Viral; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Mutation; Zidovudine

2006
[Detection of HIV infection in pregnant women by rapid testing: a successful strategy to reduce its vertical transmission].
    Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2005, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; HIV Antibodies; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Middle Aged; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prevalence; Uruguay; Zidovudine

2005
Frequency of drug-resistant variants of HIV-1 coexistent with wild-type in treatment-naive patients of India.
    MedGenMed : Medscape general medicine, 2005, Jul-27, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Viral; Female; Genes, pol; HIV Infections; HIV-1; Humans; India; Infant; Lamivudine; Male; Middle Aged; Mutation; Zidovudine

2005
Cytokine profiles in human immunodeficiency virus-infected children treated with highly active antiretroviral therapy.
    MedGenMed : Medscape general medicine, 2005, May-03, Volume: 7, Issue:2

    Topics: Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Child; Clinical Trials as Topic; Cytokines; Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Practice Guidelines as Topic; Practice Patterns, Physicians'; Prognosis; Treatment Outcome; Zidovudine

2005
In vitro mutagenicity studies of the antiretrovirals AZT, Didanosine, and 3TC and a plant antiviral extract Secomet-V derived from the Trifollium species.
    Annals of the New York Academy of Sciences, 2005, Volume: 1056

    Topics: Anti-HIV Agents; Antiviral Agents; Didanosine; Lamivudine; Mutagenicity Tests; Phytotherapy; Plant Extracts; Salmonella; Trifolium; Zidovudine

2005
Effectiveness and safety of abacavir, lamivudine, and zidovudine in antiretroviral therapy-naive HIV-infected patients: results from a large multicenter observational cohort.
    Journal of acquired immune deficiency syndromes (1999), 2006, Feb-01, Volume: 41, Issue:2

    Topics: Adult; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Hypersensitivity; Lamivudine; Male; Patient Compliance; Retrospective Studies; Spain; Treatment Failure; Zidovudine

2006
Low risk of nevirapine resistance mutations in the prevention of mother-to-child transmission of HIV-1: Agence Nationale de Recherches sur le SIDA Ditrame Plus, Abidjan, Cote d'Ivoire.
    The Journal of infectious diseases, 2006, Feb-15, Volume: 193, Issue:4

    Topics: Cote d'Ivoire; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mothers; Mutation; Nevirapine; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2006
[HIV infection presenting with bilateral optic neuropathy].
    Revue neurologique, 2006, Volume: 162, Issue:1

    Topics: AIDS Serodiagnosis; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Disease Progression; Drug Therapy, Combination; Evoked Potentials, Visual; Facial Nerve Diseases; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Ischemia; Lamivudine; Lopinavir; Male; Meningitis, Viral; Methylprednisolone; Middle Aged; Optic Disk; Optic Nerve Diseases; Polyradiculopathy; Pyrimidinones; Reverse Transcriptase Inhibitors; Ritonavir; Visual Fields; Zidovudine

2006
Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.
    AIDS (London, England), 2006, Mar-21, Volume: 20, Issue:5

    Topics: Animals; DNA; DNA, Mitochondrial; Echocardiography; Genes, pol; HIV Infections; HIV-1; Humans; Immunoblotting; Lamivudine; Membrane Transport Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Models, Molecular; Myocardium; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Stavudine; Zidovudine

2006
Virological response to HIV-1 nucleoside/nucleotide reverse transcriptase inhibitors-based, tenofovir DF-including regimens in the ANRS Aquitaine Cohort.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, Volume: 36, Issue:2

    Topics: Adenine; Cohort Studies; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; France; HIV Infections; HIV Reverse Transcriptase; HIV-1; Hospitals, University; Humans; Lamivudine; Mutation; Organophosphonates; Retrospective Studies; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2006
Unrecognized near-fatal hyperlactatemia in an HIV-infected infant exposed to nucleoside reverse transcriptase inhibitors.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2007, Volume: 11, Issue:1

    Topics: Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Lactates; Lamivudine; Male; Mitochondria; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2007
Exposure to HIV and antiretroviral medication as a potential cause of necrotizing enterocolitis in term neonates.
    AIDS (London, England), 2006, Apr-24, Volume: 20, Issue:7

    Topics: Anti-HIV Agents; Enterocolitis, Necrotizing; HIV Seropositivity; Humans; Infant, Newborn; Lamivudine; Male; Nevirapine; Risk Factors; Zidovudine

2006
Lung cancer as an immune reconstitution disease in an HIV-1 positive man receiving HAART.
    Postepy higieny i medycyny doswiadczalnej (Online), 2006, Volume: 60

    Topics: Adult; Antiretroviral Therapy, Highly Active; Carcinoma, Small Cell; Fatal Outcome; HIV Seropositivity; Humans; Lamivudine; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Ritonavir; Saquinavir; Zidovudine

2006
Relationship between antiretrovirals used as part of a cART regimen and CD4 cell count increases in patients with suppressed viremia.
    AIDS (London, England), 2006, May-12, Volume: 20, Issue:8

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Viral Load; Viremia; Zidovudine

2006
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
    The New England journal of medicine, 2006, Jun-08, Volume: 354, Issue:23

    Topics: Adenine; Anti-Retroviral Agents; Bias; Data Interpretation, Statistical; Deoxycytidine; Emtricitabine; HIV Infections; Humans; Lamivudine; Organophosphonates; Research Design; Tenofovir; Zidovudine

2006
Electronic chip fights counterfeiting.
    AIDS patient care and STDs, 2006, Volume: 20, Issue:5

    Topics: Anti-HIV Agents; Dideoxynucleosides; Drug Combinations; Drug Industry; Drug Labeling; Electronics; Fraud; HIV Infections; Humans; Lamivudine; United States; Zidovudine

2006
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
    The New England journal of medicine, 2006, Jun-08, Volume: 354, Issue:23

    Topics: Adenine; Bone Density; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2006
Virological and immunological response to Combivir and emergence of drug resistance mutations in a cohort of HIV-2 patients in The Gambia.
    AIDS (London, England), 2006, Jun-26, Volume: 20, Issue:10

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Combinations; Drug Resistance, Viral; HIV Infections; HIV-2; Humans; Lamivudine; Mutation; Viral Load; Zidovudine

2006
Rapid improvement of liver function in a patient with HIV and hepatitis B coinfection treated with lamivudine and tenofovir.
    Infection, 2006, Volume: 34, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; Hepatitis; HIV Infections; Humans; Lamivudine; Liver Function Tests; Organophosphonates; Tenofovir; Zidovudine

2006
Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion.
    European journal of medical research, 2006, Jul-31, Volume: 11, Issue:7

    Topics: Acute Disease; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; Follow-Up Studies; Histocompatibility Testing; HIV Seropositivity; HIV-1; Humans; Lamivudine; Lopinavir; Male; Pyrimidinones; Retrospective Studies; RNA, Viral; Stavudine; Treatment Outcome; Zidovudine

2006
Mitochondrial dysfunction following perinatal exposure to nucleoside analogues.
    AIDS (London, England), 2006, Aug-22, Volume: 20, Issue:13

    Topics: Anti-HIV Agents; Child; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Lamivudine; Mitochondrial Diseases; Nervous System Diseases; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Zidovudine

2006
[Adherence, pharmacokinetic "tolerance capacity" and HIV resistance development].
    Praxis, 2006, Aug-16, Volume: 95, Issue:33

    Topics: Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Diagnosis, Differential; DNA Mutational Analysis; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Treatment Refusal; Viral Load; Zidovudine

2006
Effect of nanoparticulate polybutylcyanoacrylate and methylmethacrylate-sulfopropylmethacrylate on the permeability of zidovudine and lamivudine across the in vitro blood-brain barrier.
    International journal of pharmaceutics, 2006, Dec-11, Volume: 327, Issue:1-2

    Topics: Animals; Anti-HIV Agents; Blood-Brain Barrier; Cattle; Cells, Cultured; Drug Carriers; Enbucrilate; Endothelial Cells; Ethanol; Lamivudine; Methacrylates; Nanoparticles; Particle Size; Permeability; Zidovudine

2006
Long-term safety and tolerability of the lamivudine/abacavir combination as components of highly active antiretroviral therapy.
    Drug safety, 2006, Volume: 29, Issue:9

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Controlled Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Oxazines; Prospective Studies; Time Factors; Treatment Outcome; Zidovudine

2006
[Pneumocystis jirovecii pneumonia: an old disease with a new name].
    Medicina (Kaunas, Lithuania), 2006, Volume: 42, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents, Urinary; Antifungal Agents; Drug Combinations; Drug Therapy, Combination; Female; Fluconazole; Folic Acid Antagonists; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Middle Aged; Pneumocystis carinii; Pneumonia, Pneumocystis; Radiography, Thoracic; Trimethoprim; Zidovudine

2006
Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:5

    Topics: AIDS Dementia Complex; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cells, Cultured; Drug Delivery Systems; Excipients; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Macrophages; Mice; Mice, SCID; Nelfinavir; Poloxalene; Virus Replication; Zidovudine

2007
The effects of prolonged treatment with zidovudine, lamivudine, and abacavir on a T-lymphoblastoid cell line.
    AIDS research and human retroviruses, 2006, Volume: 22, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Deoxycytidine Kinase; Dideoxynucleosides; Drug Resistance, Neoplasm; Humans; Lamivudine; Leukemia, Lymphoid; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; T-Lymphocytes; Thymidine Kinase; Zidovudine

2006
Diminished selection for thymidine-analog mutations associated with the presence of M184V in Ethiopian children infected with HIV subtype C receiving lamivudine-containing therapy.
    The Pediatric infectious disease journal, 2006, Volume: 25, Issue:11

    Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Infant; Inhibitory Concentration 50; Lamivudine; Male; Microbial Sensitivity Tests; Mutation; Phenotype; Reverse Transcriptase Inhibitors; Selection, Genetic; Thymidine; Virus Replication; Zidovudine

2006
Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleosides; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Genotype; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lysine; Mutagenesis, Site-Directed; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; Tenofovir; Thymine Nucleotides; Zidovudine

2007
[Effects of traditional Chinese medicine on CD4 + T cell counts and HIV viral loads during structured treatment interruption in highly active antiretroviral therapy].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2006, Volume: 28, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Phytotherapy; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2006
Weight and body shape changes in a treatment-naive population after 6 months of nevirapine-based generic highly active antiretroviral therapy in South India.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Jan-15, Volume: 44, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Composition; Body Weight; CD4 Lymphocyte Count; Cohort Studies; Female; HIV Infections; Humans; India; Lamivudine; Male; Nevirapine; Stavudine; Zidovudine

2007
Transcriptional profiling for understanding the basis of mitochondrial involvement in disease and toxicity using the mitochondria-specific MitoChip.
    Mutation research, 2007, Mar-01, Volume: 616, Issue:1-2

    Topics: Animals; Disease Progression; DNA, Mitochondrial; Female; Gene Expression Profiling; Lamivudine; Mice; Mitochondria; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Inhibitors; Zidovudine

2007
Human oral drugs absorption is correlated to their in vitro uptake by brush border membrane vesicles.
    International journal of pharmaceutics, 2007, May-04, Volume: 336, Issue:1

    Topics: Acetaminophen; Administration, Oral; Animals; Azlocillin; Biological Transport, Active; Cefadroxil; Doxorubicin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Lamivudine; Mannitol; Osmolar Concentration; Ouabain; Pharmaceutical Preparations; Pharmacokinetics; Phenolsulfonphthalein; Rabbits; Zidovudine

2007
Report from the XVI International AIDS Conference. Efavirenz for high viral load and low CD4--a secondary analysis of ACTG 5095.
    AIDS clinical care, 2006, Volume: 18, Issue:11

    Topics: Alkynes; Benzoxazines; CD4 Lymphocyte Count; Clinical Trials as Topic; Cyclopropanes; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Oxazines; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2006
Simultaneous measurement of intracellular triphosphate metabolites of zidovudine, lamivudine and abacavir (carbovir) in human peripheral blood mononuclear cells by combined anion exchange solid phase extraction and LC-MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, May-01, Volume: 850, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Dideoxynucleosides; HIV Infections; Humans; Lamivudine; Phosphates; Reference Standards; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Zidovudine

2007
Painless periungual pyogenic granulomata associated with reverse transcriptase inhibitor therapy in a patient with human immunodeficiency virus infection.
    The British journal of dermatology, 2007, Volume: 156, Issue:1

    Topics: Anti-HIV Agents; Drug Combinations; Granuloma, Pyogenic; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nail Diseases; Reverse Transcriptase Inhibitors; Zidovudine

2007
Persistence of lamivudine-sensitive HIV-1 quasispecies in the presence of lamivudine in vitro and in vivo.
    Journal of acquired immune deficiency syndromes (1999), 2007, Apr-01, Volume: 44, Issue:4

    Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Kinetics; Lamivudine; Mutation; Retrospective Studies; RNA, Viral; T-Lymphocytes; Time Factors; Viral Load; Virus Replication; Zidovudine

2007
Anti-HIV agents. Abacavir--as good as AZT?
    TreatmentUpdate, 2003, Volume: 15, Issue:6

    Topics: Adult; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2003
Anti-HIV agents. Low rate of early virologic failure seen with a combination of Trizivir and tenofovir.
    TreatmentUpdate, 2004, Volume: 16, Issue:2

    Topics: Adenine; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Organophosphonates; Tenofovir; Viral Load; Zidovudine

2004
Plasma lopinavir trough levels in a group of pregnant women on lopinavir, ritonavir, zidovudine, and lamivudine.
    AIDS (London, England), 2007, Mar-12, Volume: 21, Issue:5

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Pyrimidinones; Ritonavir; Viral Load; Zidovudine

2007
Less sensitive HIV-1 enzyme immunoassay as an adjuvant method for monitoring patients receiving antiretroviral therapy.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:2

    Topics: Anti-HIV Agents; Drug Monitoring; HIV Infections; HIV-1; Immunoenzyme Techniques; Indinavir; Lamivudine; Sensitivity and Specificity; Time Factors; Virus Replication; Zidovudine

2007
Evaluating the utility of ion mobility separation in combination with high-pressure liquid chromatography/mass spectrometry to facilitate detection of trace impurities in formulated drug products.
    Rapid communications in mass spectrometry : RCM, 2007, Volume: 21, Issue:7

    Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Combinations; Drug Contamination; Drug Evaluation, Preclinical; Lamivudine; Microchemistry; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Technology, Pharmaceutical; Zidovudine

2007
[Vitiligo in a black patient associated with HIV infection and repigmentation under antiretroviral therapy].
    Annales de dermatologie et de venereologie, 2007, Volume: 134, Issue:3 Pt 1

    Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Lamivudine; Nevirapine; Treatment Outcome; Vitiligo; Zidovudine

2007
Nevirapine clearance from plasma in African adults stopping therapy: a pharmacokinetic substudy.
    AIDS (London, England), 2007, Mar-30, Volume: 21, Issue:6

    Topics: Adult; Cohort Studies; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Uganda; Zidovudine; Zimbabwe

2007
Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Adenine; Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Erythrocytes; HIV Infections; Humans; Lamivudine; Nucleosides; Organophosphonates; Phosphorylation; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Zidovudine

2007
Thyrotoxic periodic paralysis in a Polynesian male following highly active antiretroviral therapy for HIV infection.
    Hawaii medical journal, 2007, Volume: 66, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Autoimmunity; Diarrhea; Drug Combinations; Genetic Predisposition to Disease; Graves Disease; Hawaii; Humans; Hypokalemic Periodic Paralysis; Iodine Radioisotopes; Lamivudine; Lopinavir; Male; Native Hawaiian or Other Pacific Islander; Polynesia; Pyrimidinones; Thyrotoxicosis; Zidovudine

2007
Hypogonadism in HIV-1-infected men is common and does not resolve during antiretroviral therapy.
    Antiviral therapy, 2007, Volume: 12, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Drug Therapy, Combination; Follicle Stimulating Hormone; HIV Infections; HIV-1; Humans; Hypogonadism; Lamivudine; Luteinizing Hormone; Male; Prevalence; Reverse Transcriptase Inhibitors; RNA, Viral; Switzerland; Testosterone; Time Factors; Treatment Outcome; Viral Load; Zidovudine

2007
Evolution of resistance mutations during low-level viral replication in HIV-1-infected patients treated with zidovudine/lamivudine/abacavir as a first-line regimen.
    Antiviral therapy, 2007, Volume: 12, Issue:1

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cohort Studies; Dideoxynucleosides; DNA, Viral; Drug Combinations; Drug Monitoring; Drug Resistance, Viral; Follow-Up Studies; Genotype; Germany; HIV Infections; HIV-1; Humans; Lamivudine; Methionine; Mutation; Reverse Transcriptase Inhibitors; Thymidine; Time Factors; Treatment Failure; Valine; Viral Load; Virus Replication; Zidovudine

2007
Assessment of adverse events associated with antiretroviral regimens for postexposure prophylaxis for occupational and nonoccupational exposures to prevent transmission of human immunodeficiency virus.
    Infection control and hospital epidemiology, 2007, Volume: 28, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Chemoprevention; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Middle Aged; New York; Occupational Exposure; Occupational Health Services; Organophosphonates; Patient Compliance; Public Health Administration; Retrospective Studies; Risk Factors; Sex Factors; Student Health Services; Tenofovir; Universities; Zidovudine

2007
Development of mitochondria-specific mouse oligonucleotide microarray and validation of data by real-time PCR.
    Mitochondrion, 2007, Volume: 7, Issue:5

    Topics: Animals; Female; Gene Expression Profiling; Lamivudine; Male; Mice; Mitochondria; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Zidovudine

2007
The HBV drug entecavir - effects on HIV-1 replication and resistance.
    The New England journal of medicine, 2007, Jun-21, Volume: 356, Issue:25

    Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B virus; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Phylogeny; Reverse Transcriptase Inhibitors; Reverse Transcription; RNA, Viral; Virus Replication; Zidovudine

2007
Long-term foscarnet therapy remodels thymidine analogue mutations and alters resistance to zidovudine and lamivudine in HIV-1.
    Antiviral therapy, 2007, Volume: 12, Issue:3

    Topics: Amino Acid Substitution; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Evolution, Molecular; Foscarnet; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Point Mutation; Reverse Transcriptase Inhibitors; Species Specificity; Thymidine; Time Factors; Zidovudine

2007
HPV oral infection. Case report of an HIV-positive Nigerian sex worker.
    Le infezioni in medicina, 2007, Volume: 15, Issue:2

    Topics: Adenine; Adult; Alphapapillomavirus; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Female; HIV Infections; Humans; Italy; Lamivudine; Lopinavir; Mouth Mucosa; Nigeria; Organophosphonates; Papillomavirus Infections; Pyrimidinones; Ritonavir; Sex Work; Stomatitis; Tenofovir; Treatment Refusal; Zidovudine

2007
Rapid and simple liquid chromatography tandem mass spectrometry method for the quantification of zidovudine in rat plasma.
    Biomedical chromatography : BMC, 2008, Volume: 22, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Injections, Intravenous; Lamivudine; Methanol; Rats; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Water; Zidovudine

2008
Antiretroviral agents and acid-base balance at delivery of the neonate.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:7

    Topics: Acid-Base Equilibrium; Adult; Anti-HIV Agents; Case-Control Studies; Drug Therapy, Combination; Female; Fetal Blood; HIV Infections; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nelfinavir; Pregnancy; Pregnancy Outcome; Prospective Studies; Zidovudine

2007
Comparison of the effectiveness of initial combined antiretroviral therapy with nelfinavir or efavirenz at a university-based outpatient service in Brazil.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:7

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Clinical Protocols; Cohort Studies; Cyclopropanes; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Retrospective Studies; RNA, Viral; Treatment Outcome; Viral Load; Zidovudine

2007
Development of a highly efficient extraction technique and specific multiplex assay for measuring antiretroviral drug concentrations in breast milk.
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:4

    Topics: Chromatography, High Pressure Liquid; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Nevirapine; Postpartum Period; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stavudine; Zidovudine

2007
Effects of antiretroviral agents during pregnancy on liver enzymes and amylase in HIV-exposed, uninfected newborn infants.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2007, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Amylases; Anti-HIV Agents; Cohort Studies; Control Groups; Drug Therapy, Combination; Female; Fetal Blood; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Liver; Male; Nelfinavir; Pregnancy; Prospective Studies; Transaminases; Zidovudine

2007
[Update on HIV infection in Mayotte].
    Medecine tropicale : revue du Corps de sante colonial, 2007, Volume: 67, Issue:2

    Topics: Adult; Anti-HIV Agents; Comoros; Dideoxynucleosides; Drug Combinations; Female; Heterosexuality; HIV Infections; HIV Seropositivity; Homosexuality; Humans; Lamivudine; Male; Middle Aged; Transfusion Reaction; Viremia; Zidovudine

2007
Prednisolone mediated suppression of HIV-1 viral load strongly correlates with C-C chemokine CCL2: In vivo and in vitro findings.
    Clinical immunology (Orlando, Fla.), 2007, Volume: 125, Issue:1

    Topics: Alkynes; Anti-HIV Agents; Anti-Inflammatory Agents; Benzoxazines; Chemokine CCL2; Cyclopropanes; Drug Resistance, Viral; Flow Cytometry; Gene Expression; HIV Infections; HIV-1; Humans; In Vitro Techniques; Interleukin-8; Lamivudine; Male; Prednisolone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Uveitis; Viral Load; Viremia; Zidovudine

2007
Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach.
    PLoS medicine, 2007, Volume: 4, Issue:8

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; CD4 Lymphocyte Count; Cohort Studies; Cote d'Ivoire; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Program Evaluation; Puerperal Disorders; Viral Load; Zidovudine

2007
Concentrations of zidovudine- and lamivudine-triphosphate according to cell type in HIV-seronegative adults.
    AIDS (London, England), 2007, Sep-12, Volume: 21, Issue:14

    Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytidine Triphosphate; Dideoxynucleotides; Drug Administration Schedule; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

2007
Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis.
    AIDS (London, England), 2007, Sep-12, Volume: 21, Issue:14

    Topics: Adenine; Administration, Oral; Adult; Alkynes; Anti-Retroviral Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; Genitalia, Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Oligopeptides; Organophosphonates; Pyridines; Pyrimidinones; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2007
Early virological response of zidovudine/lamivudine/abacavir for patients co-infected with HIV and tuberculosis in Uganda.
    AIDS (London, England), 2007, Sep-12, Volume: 21, Issue:14

    Topics: Adult; Antitubercular Agents; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Hypersensitivity; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Neutropenia; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Tuberculosis, Pulmonary; Zidovudine

2007
First use of tamoxifen in an HIV patient with encapsulating peritoneal sclerosis.
    Clinical drug investigation, 2007, Volume: 27, Issue:10

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Estrogen Antagonists; Glucocorticoids; HIV Infections; Humans; Kidney Failure, Chronic; Lamivudine; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneal Diseases; Saquinavir; Sclerosis; Tamoxifen; Zidovudine

2007
Human immunodeficiency virus infection in a child presenting as herpes zoster ophthalmicus.
    Journal of the Indian Medical Association, 2007, Volume: 105, Issue:4

    Topics: Acyclovir; Child; Eye Diseases; Herpes Zoster Ophthalmicus; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Zidovudine

2007
Efficacy of highly active antiretroviral therapy in HIV-1 infected children in Kenya.
    Pediatrics, 2007, Volume: 120, Issue:4

    Topics: Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Weight; CD4 Lymphocyte Count; Child; Child, Preschool; Drugs, Generic; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Kenya; Lamivudine; Male; Nevirapine; Prospective Studies; RNA, Viral; Viral Load; Zidovudine

2007
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy.
    Antiviral therapy, 2007, Volume: 12, Issue:6

    Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zidovudine

2007
[Rapid development of anemia in a HIV-positive patient with alpha-thalassemia after zidovudine therapy].
    Mikrobiyoloji bulteni, 2007, Volume: 41, Issue:3

    Topics: Adult; alpha-Thalassemia; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Diagnosis, Differential; Folic Acid; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Zidovudine

2007
Metabolism and pharmacokinetics of the combination Zidovudine plus Lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis.
    Toxicology and applied pharmacology, 2008, Jan-15, Volume: 226, Issue:2

    Topics: Animals; Anti-HIV Agents; Area Under Curve; Chromatography, Liquid; Drug Combinations; Erythrocebus patas; Half-Life; Lamivudine; Metabolic Clearance Rate; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Zidovudine

2008
Non-occupational post exposure prophylaxis as a biobehavioral HIV-prevention intervention.
    AIDS care, 2008, Volume: 20, Issue:3

    Topics: Adult; Anti-HIV Agents; Attitude to Health; Drug Combinations; Feasibility Studies; Female; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Risk-Taking; Treatment Outcome; Zidovudine

2008
Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Anti-HIV Agents; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lamivudine; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors; Thermodynamics; Zidovudine

2008
Liver enzymes elevation and immune reconstitution among treatment-naïve HIV-infected patients instituting antiretroviral therapy.
    The American journal of the medical sciences, 2007, Volume: 334, Issue:5

    Topics: Adult; Alanine Transaminase; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Aspartate Aminotransferases; Benzoxazines; CD4-Positive T-Lymphocytes; Cyclopropanes; Drug Therapy, Combination; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Linear Models; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Factors; Stavudine; Zidovudine

2007
Predictors of optimal viral suppression in patients switched to abacavir, lamivudine, and zidovudine: the Swiss HIV Cohort Study.
    AIDS (London, England), 2007, Oct-18, Volume: 21, Issue:16

    Topics: Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cohort Studies; Dideoxynucleosides; Drug Therapy, Combination; Female; Genes, MDR; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Prognosis; Proportional Hazards Models; Reverse Transcriptase Inhibitors; RNA, Viral; Switzerland; Treatment Failure; Viral Load; Zidovudine

2007
Evolution of bone mineral density in AIDS patients on treatment with zidovudine/lamivudine plus abacavir or lopinavir/ritonavir.
    HIV medicine, 2008, Volume: 9, Issue:2

    Topics: Absorptiometry, Photon; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; Case-Control Studies; Dideoxynucleosides; Femur Neck; HIV Infections; Humans; Lamivudine; Lopinavir; Lumbar Vertebrae; Male; Middle Aged; Prospective Studies; Pyrimidinones; Ritonavir; Zidovudine

2008
Persistence of genotypic resistance to nelfinavir among women exposed to prophylactic antiretroviral therapy during pregnancy.
    AIDS research and human retroviruses, 2007, Volume: 23, Issue:12

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nelfinavir; Pregnancy; Pregnancy Complications, Infectious; Viral Load; Zidovudine

2007
Effect of isolated V118I mutation in reverse transcriptase on response to first-line antiretroviral therapy.
    AIDS (London, England), 2008, Jan-30, Volume: 22, Issue:3

    Topics: Adult; Anti-HIV Agents; Case-Control Studies; CD4 Lymphocyte Count; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine

2008
Maternal 12-month response to antiretroviral therapy following prevention of mother-to-child transmission of HIV type 1, Ivory Coast, 2003-2006.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Feb-15, Volume: 46, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cote d'Ivoire; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Microbial Sensitivity Tests; Nevirapine; Pregnancy; RNA, Viral; Treatment Outcome; Treatment Refusal; Viral Load; Zidovudine

2008
18-month effectiveness of short-course antiretroviral regimens combined with alternatives to breastfeeding to prevent HIV mother-to-child transmission.
    PloS one, 2008, Feb-20, Volume: 3, Issue:2

    Topics: Africa; Anti-HIV Agents; Breast Feeding; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Proportional Hazards Models; Survival Rate; Treatment Outcome; Zidovudine

2008
Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.
    Journal of neurovirology, 2008, Volume: 14, Issue:1

    Topics: Adenine; Adult; AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Anticonvulsants; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cerebrospinal Fluid; Cyclopropanes; Didanosine; HIV-1; Humans; Indinavir; Lamivudine; Male; Nelfinavir; Nevirapine; Oligopeptides; Organophosphonates; Pyridines; Ritonavir; Seizures; Stavudine; Tenofovir; Viral Load; Virus Replication; Zidovudine

2008
Nucleoside reverse transcriptase inhibitors (NRTIs)-induced expression profile of mitochondria-related genes in the mouse liver.
    Mitochondrion, 2008, Volume: 8, Issue:2

    Topics: Animals; Citric Acid Cycle; DNA, Mitochondrial; Female; Gene Expression Regulation; Lamivudine; Lipid Metabolism; Liver; Male; Mice; Microarray Analysis; Mitochondria; Oxidative Phosphorylation; Reverse Transcriptase Inhibitors; RNA; RNA, Mitochondrial; Steroids; Zidovudine

2008
HIV/AIDS treatment and physicochemical quality control of medicines: evaluation of non-generic lamivudine + zidovudine tablets manufactured in Brazil.
    The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2007, Volume: 11, Issue:6

    Topics: Anti-HIV Agents; Brazil; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Industry; Lamivudine; Quality Control; Tablets; Zidovudine

2007
Cost-effectiveness analysis of emtricitabine/tenofovir versus lamivudine/zidovudine, in combination with efavirenz, in antiretroviral-naive, HIV-1-infected patients.
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cost-Benefit Analysis; Cyclopropanes; Decision Trees; Deoxycytidine; Drug Costs; Emtricitabine; Health Care Costs; Health Resources; HIV Infections; HIV-1; Humans; Lamivudine; Models, Economic; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Time Factors; Treatment Outcome; Zidovudine

2008
Differential extracellular and intracellular concentrations of zidovudine and lamivudine in semen and plasma of HIV-1-infected men.
    Journal of acquired immune deficiency syndromes (1999), 2008, Jun-01, Volume: 48, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Area Under Curve; CD4 Lymphocyte Count; Extracellular Fluid; HIV-1; Humans; Intracellular Fluid; Lamivudine; Male; RNA, Viral; Semen; Zidovudine

2008
Noise-induced hearing loss in mice treated with antiretroviral drugs.
    Hearing research, 2008, Volume: 239, Issue:1-2

    Topics: Animals; Anti-Retroviral Agents; Brain Stem; Evoked Potentials, Auditory, Brain Stem; Female; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Lamivudine; Mice; Mice, Inbred CBA; Models, Statistical; Otoacoustic Emissions, Spontaneous; Time Factors; Treatment Outcome; Zidovudine

2008
Prospective cohort study of HIV post-exposure prophylaxis for sexual assault survivors.
    Antiviral therapy, 2008, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Child; Child, Preschool; Cohort Studies; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Ontario; Pyrimidinones; Rape; Risk Factors; Zidovudine

2008
FDA notifications. Tentative approval for generic lamivudine/zidovudine.
    AIDS alert, 2007, Volume: 22, Issue:10

    Topics: Drug Approval; Drug Combinations; Drugs, Generic; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

2007
High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Anti-HIV Agents; Dideoxynucleotides; Female; Follow-Up Studies; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Leukocytes, Mononuclear; Male; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Thymine Nucleotides; Zidovudine

2008
Rapid scaling-up of antiretroviral therapy in 10,000 adults in Côte d'Ivoire: 2-year outcomes and determinants.
    AIDS (London, England), 2008, Apr-23, Volume: 22, Issue:7

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cote d'Ivoire; Drug Administration Schedule; Female; Follow-Up Studies; HIV; HIV Infections; HIV-1; HIV-2; Humans; Lamivudine; Male; Nevirapine; Survival Analysis; Treatment Outcome; Zidovudine

2008
New formulations approved for children.
    AIDS patient care and STDs, 2008, Volume: 22, Issue:1

    Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Child; Child, Preschool; Dideoxynucleosides; Drug Approval; Drug Combinations; European Union; HIV Infections; Humans; Infant; Infant, Newborn; Lamivudine; Reverse Transcriptase Inhibitors; Zidovudine

2008
Targeting only reverse transcriptase with zidovudine/lamivudine/abacavir plus tenofovir in HIV-1-infected patients with multidrug-resistant virus: a multicentre pilot study.
    HIV medicine, 2008, Volume: 9, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Pilot Projects; Reverse Transcriptase Inhibitors; RNA, Viral; Tenofovir; Thymidine; Viral Load; Zidovudine

2008
[Evaluation of antiretroviral therapy in HIV-infected adults in the Department of Haematology, University Hospital of Brazzavllle, Congo].
    Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:2

    Topics: Adolescent; Adult; Aged; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Congo; Cyclopropanes; Didanosine; Drug Evaluation; Drug Therapy, Combination; Female; Hematology; HIV Infections; Hospital Departments; Hospitals, University; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2008
Cytokine and sex hormone effects on zidovudine- and lamivudine-triphosphate concentrations in vitro.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 62, Issue:4

    Topics: Adipocytes; Cytidine Triphosphate; Cytokines; Dideoxynucleotides; Female; Gonadal Steroid Hormones; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Zidovudine

2008
The nucleoside reverse transcriptase inhibitors didanosine, lamivudine, stavudine and zidovudine show little effect on the virulence of Candida albicans in vitro.
    International journal of antimicrobial agents, 2008, Volume: 32, Issue:2

    Topics: Antifungal Agents; Biofilms; Candida albicans; Cell Adhesion; Cell Line; Didanosine; Humans; Lamivudine; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors; Stavudine; Virulence; Zidovudine

2008
FDA notifications. FDA approval for generic lamivudine/zidovudine.
    AIDS alert, 2008, Volume: 23, Issue:1

    Topics: Drug Approval; Drugs, Generic; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

2008
Modelled in vivo HIV fitness under drug selective pressure and estimated genetic barrier towards resistance are predictive for virological response.
    Antiviral therapy, 2008, Volume: 13, Issue:3

    Topics: Adult; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Models, Biological; Mutation; Nelfinavir; Predictive Value of Tests; Retrospective Studies; Reverse Transcriptase Inhibitors; Time Factors; Treatment Failure; Viral Load; Zidovudine

2008
[Screening of HIV-1 replication inhibitors by using pseudotyped virus system].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:3

    Topics: Anti-HIV Agents; Didanosine; DNA Replication; Drug Evaluation, Preclinical; Genes, Reporter; HIV-1; Humans; Lamivudine; Pseudocowpox Virus; Tumor Cells, Cultured; Virus Replication; Zidovudine

2008
Noncirrhotic portal hypertension in patients with human immunodeficiency virus-1 infection.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:10

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Female; HIV Infections; HIV-1; Humans; Hypertension, Portal; Lamivudine; Male; Middle Aged; Risk Factors; Thrombophilia; Viral Load; Zidovudine

2008
Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region.
    Journal of molecular biology, 2008, Oct-03, Volume: 382, Issue:2

    Topics: Amino Acid Sequence; Anti-HIV Agents; Codon; Crystallography, X-Ray; Deoxycytosine Nucleotides; DNA, Viral; Drug Resistance, Multiple, Viral; Foscarnet; HIV Infections; HIV Reverse Transcriptase; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Conformation; Reverse Transcriptase Inhibitors; Sequence Alignment; Sequence Deletion; Zidovudine

2008
Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire.
    AIDS (London, England), 2008, Sep-12, Volume: 22, Issue:14

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cote d'Ivoire; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Infant, Low Birth Weight; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Nevirapine; Perinatal Mortality; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Zidovudine

2008
A case of human bite by an 11-year old HIV positive girl in a paediatrics ward.
    African journal of medicine and medical sciences, 2008, Volume: 37, Issue:1

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Bites, Human; Child; Cyclopropanes; Female; HIV Infections; Humans; Inpatients; Lamivudine; Male; Zidovudine

2008
Incidence of abacavir hypersensitivity reactions in euroSIDA.
    Antiviral therapy, 2008, Volume: 13, Issue:5

    Topics: Adult; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Europe; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Middle Aged; Poisson Distribution; Reverse Transcriptase Inhibitors; Treatment Outcome; Zidovudine

2008
New depot forms of AZT and 3TC based on their phosphonate derivatives: anti-HIV activity and pharmacokinetic parameters.
    Nucleic acids symposium series (2004), 2008, Issue:52

    Topics: Animals; Antiviral Agents; Cell Line; Dogs; Lamivudine; Mice; Organophosphonates; Zidovudine

2008
Two-year outcomes of children on non-nucleoside reverse transcriptase inhibitor and protease inhibitor regimens in a South African pediatric antiretroviral program.
    The Pediatric infectious disease journal, 2008, Volume: 27, Issue:11

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Cohort Studies; Didanosine; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Lopinavir; Male; Multivariate Analysis; Pyrimidinones; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; South Africa; Stavudine; Treatment Outcome; Zidovudine

2008
Interference of cell cycle progression by zidovudine and lamivudine in NIH 3T3 cells.
    Mutagenesis, 2009, Volume: 24, Issue:2

    Topics: Animals; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Proliferation; Cell Survival; DNA; Flow Cytometry; Lamivudine; Mice; Necrosis; NIH 3T3 Cells; Zidovudine

2009
HIV postexposure prophylaxis after sexual assault: why is it so hard to accomplish?
    Sexually transmitted diseases, 2008, Volume: 35, Issue:12

    Topics: Adolescent; Animals; Anti-HIV Agents; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Macaca mulatta; Pyrimidinones; Sex Offenses; Zidovudine

2008
The use of shift reagents in ion mobility-mass spectrometry: studies on the complexation of an active pharmaceutical ingredient with polyethylene glycol excipients.
    Journal of the American Society for Mass Spectrometry, 2009, Volume: 20, Issue:1

    Topics: Algorithms; Anti-HIV Agents; Cations; Chemistry, Pharmaceutical; Drug Combinations; Excipients; Lamivudine; Polyethylene Glycols; Protons; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Zidovudine

2009
Tolerability of fosamprenavir/ritonavir associated with zidovudine-lamivudine used as postexposure prophylaxis for HIV infection.
    Journal of acquired immune deficiency syndromes (1999), 2008, Nov-01, Volume: 49, Issue:3

    Topics: Adult; Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Female; Furans; HIV Infections; Humans; Lamivudine; Male; Organophosphates; Prospective Studies; Ritonavir; Sulfonamides; Zidovudine

2008
[A case of acquired encephalopathy in a child. A cause that we thought had disappeared].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2008, Volume: 15, Issue:12

    Topics: AIDS Dementia Complex; Anti-HIV Agents; Anti-Infective Agents; Drug Therapy, Combination; Female; Fluconazole; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Polymerase Chain Reaction; Pyrimidinones; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine

2008
Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1.
    Environmental and molecular mutagenesis, 2009, Volume: 50, Issue:1

    Topics: Base Sequence; Case-Control Studies; DNA Primers; DNA, Mitochondrial; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Mutation; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; RNA, Transfer; Umbilical Cord; Zidovudine

2009
Doxorubicin-induced hyperpigmentation.
    Dermatology online journal, 2008, Oct-15, Volume: 14, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Carbamates; Doxorubicin; Drug Combinations; Furans; Humans; Lamivudine; Lip Diseases; Male; Melanosis; Nails, Malformed; Organophosphates; Ritonavir; Sarcoma, Kaposi; Sulfonamides; Tongue Diseases; Zidovudine

2008
Murine cardiac mtDNA: effects of transgenic manipulation of nucleoside phosphorylation.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:2

    Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cardiomyopathy, Dilated; Cell Line; DNA, Mitochondrial; Echocardiography; Female; Heart Ventricles; Hypertrophy, Left Ventricular; Indinavir; Lamivudine; Male; Mice; Mice, Transgenic; Mitochondria, Heart; Myocytes, Cardiac; Phosphorylation; Reverse Transcriptase Inhibitors; Thymidine Kinase; Zidovudine

2009
Development of a liquid chromatographic assay for an anti-HIV tablet containing lamivudine, zidovudine and TMC278.HCL.
    Journal of pharmaceutical and biomedical analysis, 2009, Feb-20, Volume: 49, Issue:2

    Topics: Anti-HIV Agents; Biological Assay; Calibration; Chemistry, Pharmaceutical; Chromatography, Liquid; HIV; Humans; Lamivudine; Light; Molecular Structure; Nitriles; Pyrimidines; Reference Standards; Rilpivirine; Scattering, Radiation; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet; Tablets; Zidovudine

2009
Antiretroviral concentrations in breast-feeding infants of mothers receiving highly active antiretroviral therapy.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Blood; Breast Feeding; Clinical Trials, Phase II as Topic; Desiccation; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lactation; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Young Adult; Zidovudine

2009
A prospective study evaluating clinical outcomes and costs of three NNRTI-based HAART regimens in Kerala, India.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; India; Lamivudine; Male; Medication Adherence; Nevirapine; Prospective Studies; Stavudine; Treatment Outcome; Zidovudine

2009
Transport of lamivudine [(-)-beta-L-2',3'-dideoxy-3'-thiacytidine] and high-affinity interaction of nucleoside reverse transcriptase inhibitors with human organic cation transporters 1, 2, and 3.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Animals; Anti-HIV Agents; Binding Sites; Biological Transport, Active; CHO Cells; Cricetinae; Cricetulus; Dideoxynucleosides; Drug Interactions; Humans; Kinetics; Lamivudine; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Reverse Transcriptase Inhibitors; Transfection; Zidovudine

2009
[Analysis of pre-treatment screening on 160 HIV/AIDS patients receiving highly active antiretroviral therapy ( AZT +3TC + EFV) treatment].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2008, Volume: 29, Issue:11

    Topics: Adult; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Treatment Outcome; Zidovudine

2008
Switching Combivir to Truvada keeps HIV undetectable, improves blood fats, fails to improve limb fat.
    Project Inform perspective, 2008, Issue:47

    Topics: Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Lamivudine; Lipids; Lipodystrophy; Organophosphorus Compounds; Viral Load; Zidovudine

2008
Improvement of sensitivity and selectivity of high-performance liquid chromatography for anti-retroviral drugs (non-reverse transcriptase inhibitors) by diamond-electrode electrochemical and fluorescence detection.
    Journal of chromatography. A, 2009, Apr-10, Volume: 1216, Issue:15

    Topics: Anti-Retroviral Agents; Chromatography, High Pressure Liquid; Didanosine; Dideoxynucleosides; Electrochemical Techniques; Fluorescence; Humans; Lamivudine; Linear Models; Reproducibility of Results; Reverse Transcriptase Inhibitors; Sensitivity and Specificity; Water; Zidovudine

2009
Prevention of vaginal simian immunodeficiency virus transmission in macaques by postexposure prophylaxis with zidovudine, lamivudine and indinavir.
    AIDS (London, England), 2009, Feb-20, Volume: 23, Issue:4

    Topics: Administration, Oral; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Indinavir; Injections, Subcutaneous; Lamivudine; Macaca fascicularis; Sexually Transmitted Diseases, Viral; Simian Acquired Immunodeficiency Syndrome; Vagina; Viral Load; Viremia; Zidovudine

2009
Emergence of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child.
    PloS one, 2009, Volume: 4, Issue:3

    Topics: Adult; Antiretroviral Therapy, Highly Active; Didanosine; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation, Missense; Nelfinavir; Phylogeny; Point Mutation; Pregnancy; Pregnancy Complications, Infectious; Selection, Genetic; Zidovudine

2009
Resistance to antiretrovirals in HIV-infected pregnant women.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, Volume: 45, Issue:1

    Topics: Adult; Anti-HIV Agents; Data Interpretation, Statistical; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Viral Load; Zidovudine

2009
The obstetric face and challenge of HIV/AIDS.
    Clinical obstetrics and gynecology, 2009, Volume: 52, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Anti-Infective Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; Developing Countries; Disease Progression; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Maternal Mortality; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Trimethoprim, Sulfamethoxazole Drug Combination; World Health Organization; Zidovudine

2009
Lamivudine/zidovudine: paediatric indication. For certain HIV-infected children.
    Prescrire international, 2008, Volume: 17, Issue:98

    Topics: Child; Drug Approval; Drug Therapy, Combination; Europe; HIV Infections; Humans; Lamivudine; Zidovudine

2008
[Raised tattoos in a human-immunodeficiency-virus-infected patient].
    Enfermedades infecciosas y microbiologia clinica, 2009, Volume: 27, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiprotozoal Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Hepatitis C, Chronic; Histiocytes; Humans; Lamivudine; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Lopinavir; Male; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Patient Compliance; Pentamidine; Pyrimidinones; Recurrence; Ritonavir; Tattooing; Zidovudine

2009
Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants.
    Journal of clinical microbiology, 2009, Volume: 47, Issue:7

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; Gambia; HIV Infections; HIV Protease; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Lamivudine; Longitudinal Studies; Lopinavir; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Pyrimidinones; Ritonavir; Sequence Analysis, DNA; Treatment Outcome; Viral Load; Zidovudine

2009
Quadruple nucleos(t)ide reverse transcriptase inhibitors-only regimen of tenofovir plus zidovudine/lamivudine/abacavir in heavily pre-treated HIV-1 infected patients: salvage therapy or backbone only?
    Current HIV research, 2009, Volume: 7, Issue:3

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count; Dideoxynucleosides; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation, Missense; Organophosphonates; Retrospective Studies; Salvage Therapy; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2009
Comparison of bidirectional lamivudine and zidovudine transport using MDCK, MDCK-MDR1, and Caco-2 cell monolayers.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:11

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Humans; Lamivudine; Tetrahydroisoquinolines; Zidovudine

2009
Virological and immunological stability in HIV infected patients undergoing partial-treatment interruption.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, Volume: 45, Issue:4

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Drug Combinations; Drug Resistance, Viral; Enfuvirtide; Female; HIV Envelope Protein gp41; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Peptide Fragments; Treatment Outcome; Viral Load; Withholding Treatment; Zidovudine

2009
[Tolerance study of a triple first-line antiretroviral combination zidovudine, lamivudine and efavirenz in Dakar, Senegal].
    Bulletin de la Societe de pathologie exotique (1990), 2009, Volume: 102, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Anemia; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Drug Tolerance; HIV-1; Humans; Lamivudine; Senegal; Zidovudine

2009
Adherence to antiretroviral drug therapy in children with HIV/AIDS in Jamaica.
    The West Indian medical journal, 2008, Volume: 57, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Anti-HIV Agents; Anti-Retroviral Agents; Biomarkers; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Female; HIV Infections; Humans; Infant; Jamaica; Lamivudine; Male; Medication Adherence; Nevirapine; Surveys and Questionnaires; Young Adult; Zidovudine

2008
The absence of HIV mutations in cerebrospinal fluid and in peripheral blood mononuclear cells during a regimen containing Trizivir plus tenofovir.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:4

    Topics: Adenine; Anti-HIV Agents; Cohort Studies; Drug Combinations; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Mutation; Organophosphonates; Prospective Studies; Tenofovir; Viremia; Zidovudine

2009
Confluent molluscum contagiosum covering the eyelids of an HIV-positive child.
    Clinical & experimental ophthalmology, 2009, Volume: 37, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Child, Preschool; Drug Therapy, Combination; Eye Infections, Viral; Eyelid Diseases; HIV Seropositivity; Humans; Lamivudine; Male; Molluscum Contagiosum; Nevirapine; Trimethoprim, Sulfamethoxazole Drug Combination; Viral Load; Zidovudine

2009
FDA notifications. Generic lamivudine/zidovudine approved.
    AIDS alert, 2009, Volume: 24, Issue:7

    Topics: Drug Approval; Drug Combinations; Drugs, Generic; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

2009
FDA notifications. Lamivudine/zidovudine tab tentatively approved.
    AIDS alert, 2009, Volume: 24, Issue:7

    Topics: Drug Approval; Drug Combinations; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tablets; United States; United States Food and Drug Administration; Zidovudine

2009
Mother-to-child HIV and HHV-8 transmission in neonates at Saint Camille Medical Centre in Burkina Faso.
    Pakistan journal of biological sciences : PJBS, 2009, Jun-15, Volume: 12, Issue:12

    Topics: Adult; Anti-HIV Agents; Burkina Faso; CD4 Lymphocyte Count; DNA, Viral; Female; Herpesviridae Infections; Herpesvirus 8, Human; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Young Adult; Zidovudine

2009
Serial knife stabbings with HIV exposure--implications for post-exposure prophylaxis.
    The Journal of infection, 2010, Volume: 60, Issue:1

    Topics: Anti-HIV Agents; Crime Victims; Disease Transmission, Infectious; Drug Combinations; Hepatitis B; Hepatitis C; HIV Infections; Humans; Lamivudine; Lopinavir; Post-Exposure Prophylaxis; Pyrimidinones; Viral Load; Wounds, Stab; Zidovudine

2010
Antiretroviral strategies to prevent mother-to-child transmission of HIV: striking a balance between efficacy, feasibility, and resistance.
    PLoS medicine, 2009, Volume: 6, Issue:10

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2009
Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy.
    AIDS (London, England), 2010, Jan-02, Volume: 24, Issue:1

    Topics: Adult; Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Zidovudine

2010
FDA notifications. Tentative approval given for combination of abacavir, lamivudine & zidovudine tablets.
    AIDS alert, 2009, Volume: 24, Issue:9

    Topics: Dideoxynucleosides; Drug Approval; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tablets; United States; United States Food and Drug Administration; Zidovudine

2009
Satisfactory cross-cultural validity of the ACTG symptom distress module in HIV-1-infected antiretroviral-naive patients.
    Clinical trials (London, England), 2009, Volume: 6, Issue:6

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cultural Competency; Cyclohexanes; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Language; Male; Maraviroc; Middle Aged; Multicenter Studies as Topic; Psychometrics; Randomized Controlled Trials as Topic; Reproducibility of Results; Stress, Psychological; Surveys and Questionnaires; Triazoles; Zidovudine

2009
Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women.
    Pediatrics, 2009, Volume: 124, Issue:6

    Topics: Anti-HIV Agents; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Longitudinal Studies; Monocytes; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Prenatal Exposure Delayed Effects; Reference Values; Reverse Transcriptase Inhibitors; Zidovudine

2009
FDA notifications. Lamivudine/zidovudine combination approved for pediatric use.
    AIDS alert, 2009, Volume: 24, Issue:9

    Topics: Child; Drug Approval; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

2009
Development of an allele-specific PCR for detection of the K65R resistance mutation in patients infected with subtype C human immunodeficiency virus type 1.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2

    Topics: Alkynes; Alleles; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Polymerase Chain Reaction; Zidovudine

2010
Low-abundance HIV species and their impact on mutational profiles in patients with virological failure on once-daily abacavir/lamivudine/zidovudine and tenofovir.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; Organophosphonates; RNA, Viral; Tenofovir; Treatment Failure; Viremia; Young Adult; Zidovudine

2010
Specification of covariance structure in longitudinal data analysis for randomized clinical trials.
    Statistics in medicine, 2010, Feb-20, Volume: 29, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Bias; CD4 Lymphocyte Count; Computer Simulation; Humans; Indinavir; Lamivudine; Longitudinal Studies; Models, Statistical; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Zidovudine

2010
Postmarketing in vitro/in vivo assessment of fixed dose combination products of first line antiretrovirals.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:6

    Topics: Antiviral Agents; Area Under Curve; Chromatography, High Pressure Liquid; Clinical Protocols; Confidence Intervals; Drugs, Generic; Humans; Lamivudine; Pharmaceutical Preparations; Tablets; Therapeutic Equivalency; Zidovudine

2010
Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.
    Archives of internal medicine, 2010, Jan-11, Volume: 170, Issue:1

    Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Oligopeptides; Organophosphonates; Proportional Hazards Models; Prospective Studies; Pyridines; Pyrimidinones; Risk Factors; Switzerland; Tenofovir; Zidovudine

2010
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:1

    Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Echocardiography; Female; Fetus; Heart; Lamivudine; Male; Maternal-Fetal Exchange; Mice; Microscopy, Electron, Transmission; Mitochondria, Heart; Mutation; Myocardium; Organ Size; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Sex Characteristics; Zidovudine

2010
In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:2

    Topics: Animals; Anti-HIV Agents; DNA, Mitochondrial; Drug Interactions; Drug Therapy, Combination; Echocardiography; Electron Transport Chain Complex Proteins; Electrophoresis, Polyacrylamide Gel; Female; Heart; Lamivudine; Luminescent Measurements; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardium; Oxidative Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors; Zidovudine

2010
Epidemiological and biological evidence for a compensatory effect of connection domain mutation N348I on M184V in HIV-1 reverse transcriptase.
    The Journal of infectious diseases, 2010, Apr-01, Volume: 201, Issue:7

    Topics: Cell Line; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Ribonuclease H, Human Immunodeficiency Virus; Selection, Genetic; Statistics, Nonparametric; Zidovudine

2010
Analysis of RT sequences of subtype C HIV-type 1 isolates from indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines.
    AIDS research and human retroviruses, 2010, Volume: 26, Issue:3

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; India; Lamivudine; Molecular Sequence Data; Nevirapine; Polymorphism, Single Nucleotide; Stavudine; Treatment Failure; Zidovudine

2010
Resistance pathways of human immunodeficiency virus type 1 against the combination of zidovudine and lamivudine.
    The Journal of general virology, 2010, Volume: 91, Issue:Pt 8

    Topics: Anti-HIV Agents; Drug Resistance, Viral; Drug Therapy, Combination; Evolution, Molecular; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation, Missense; Point Mutation; RNA, Viral; Selection, Genetic; Zidovudine

2010
[Durability and tolerability of long-term nevirapine-based HAART].
    Le infezioni in medicina, 2010, Volume: 18, Issue:1

    Topics: Adult; Aged; Antiretroviral Therapy, Highly Active; Comorbidity; Dideoxynucleosides; Female; Hepatitis, Viral, Human; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lipids; Liver Function Tests; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Viral Load; Young Adult; Zidovudine

2010
Identification, isolation, and characterization of potential degradation products in a triple combination lamivudine, zidovudine, and nevirapine tablet for oral suspension.
    Die Pharmazie, 2010, Volume: 65, Issue:5

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Contamination; Indicators and Reagents; Lamivudine; Magnetic Resonance Spectroscopy; Nevirapine; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Suspensions; Tablets; Zidovudine

2010
Simultaneous determination of stavudine and lamivudine in human plasma by high performance liquid chromatography and its application to a bioavailability study.
    The Southeast Asian journal of tropical medicine and public health, 2010, Volume: 41, Issue:2

    Topics: Anti-HIV Agents; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Humans; Lamivudine; Reference Standards; Stavudine; Zidovudine

2010
Addition of 7 days of zidovudine plus lamivudine to peripartum single-dose nevirapine effectively reduces nevirapine resistance postpartum in HIV-infected mothers in Malawi.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Anti-HIV Agents; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Malawi; Nevirapine; Plasma; Polymerase Chain Reaction; Postpartum Period; Pregnancy; RNA, Viral; Sequence Analysis, DNA; Young Adult; Zidovudine

2010
Immunological response to highly active antiretroviral therapy following treatment for prevention of mother to child transmission of HIV-1: a study in Côte d'Ivoire.
    Journal of the International AIDS Society, 2010, Aug-02, Volume: 13

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cote d'Ivoire; Female; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Treatment Outcome; Zidovudine

2010
Evolution of drug resistance during 48 weeks of zidovudine/lamivudine/tenofovir in the absence of real-time viral load monitoring.
    Journal of acquired immune deficiency syndromes (1999), 2010, Volume: 55, Issue:2

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Genotype; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Tenofovir; Time Factors; Viral Load; Zidovudine

2010
Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs).
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:1

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Didanosine; Disease Models, Animal; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Lamivudine; Maternal Exposure; Mitochondria, Liver; Oxidative Phosphorylation; Pregnancy; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2010
Recent FDA approvals and changes.
    AIDS patient care and STDs, 2010, Volume: 24, Issue:8

    Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Approval; Drug Combinations; Drugs, Generic; HIV Antibodies; HIV Core Protein p24; HIV Infections; HIV-1; HIV-2; Humans; Lamivudine; Nevirapine; Reagent Kits, Diagnostic; Reverse Transcriptase Inhibitors; Tablets; United States; United States Food and Drug Administration; Zidovudine

2010
Genotypic and phenotypic cross-drug resistance of harboring drug-resistant HIV type 1 subtype B' strains from former blood donors in central Chinese provinces.
    AIDS research and human retroviruses, 2010, Volume: 26, Issue:9

    Topics: Adult; Anti-HIV Agents; Blood Donors; China; Didanosine; Drug Resistance, Multiple, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Phenotype; pol Gene Products, Human Immunodeficiency Virus; RNA, Viral; Sequence Analysis, RNA; Stavudine; Zidovudine

2010
Stavudine toxicity in women is the main reason for treatment change in a 3-year prospective cohort of adult patients started on first-line antiretroviral treatment in Uganda.
    Journal of acquired immune deficiency syndromes (1999), 2011, Jan-01, Volume: 56, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Female; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Multivariate Analysis; Nevirapine; Prospective Studies; Risk Factors; Sex Factors; Stavudine; Uganda; Zidovudine

2011
Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion.
    Retrovirology, 2010, Sep-26, Volume: 7

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiretroviral Therapy, Highly Active; Drug Administration Schedule; HIV Protease Inhibitors; Indinavir; Lamivudine; Macaca fascicularis; Male; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Time Factors; Tissue Distribution; Viremia; Zidovudine

2010
Evaluating patients for second-line antiretroviral therapy in India: the role of targeted viral load testing.
    Journal of acquired immune deficiency syndromes (1999), 2010, Dec-15, Volume: 55, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Female; HIV; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; RNA, Viral; Stavudine; Treatment Failure; Viral Load; Zidovudine

2010
[Human immunodeficiency virus and Chagas disease coinfection treated successfully with benznidazole and a raltegravir-based antiretroviral regimen: a case report].
    Medicina clinica, 2011, Sep-10, Volume: 137, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Chagas Disease; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Nitroimidazoles; Oligopeptides; Organophosphonates; Paraguay; Pyridines; Pyrrolidinones; Raltegravir Potassium; Ritonavir; Spain; Tenofovir; Trypanocidal Agents; Zidovudine

2011
Reduced dose of stavudine and lipoatrophy in HIV-infected patients in Cameroon.
    Antiviral therapy, 2010, Volume: 15, Issue:7

    Topics: Adult; Anti-HIV Agents; Cameroon; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Male; Middle Aged; Nevirapine; Stavudine; Zidovudine

2010
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1

    Topics: Adenine; Anti-HIV Agents; DNA-Directed DNA Polymerase; Humans; Lamivudine; Molecular Structure; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tenofovir; Zidovudine

2011
Determinants of individual variation in intracellular accumulation of anti-HIV nucleoside analog metabolites.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2

    Topics: Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cross-Sectional Studies; Deoxycytidine Kinase; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Nucleosides; Polyphosphates; Sex Factors; Stavudine; Thymidine Kinase; Treatment Outcome; Zidovudine

2011
Aminotransferase serum levels decrease after initiating antiretroviral treatment in HIV infected patients.
    Current HIV research, 2011, Volume: 9, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Lopinavir; Male; Pyrimidinones; Ritonavir; Serum; Transaminases; Zidovudine

2011
[Morphological and physiological analysis of livers and kidneys of pregnant rats and their fetuses treated by the association of zidovudine, lamivudine and ritonavir for the whole period of pregnancy].
    Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2010, Volume: 32, Issue:11

    Topics: Animals; Anti-HIV Agents; Female; Fetus; Kidney; Lamivudine; Liver; Pregnancy; Rats; Rats, Wistar; Ritonavir; Zidovudine

2010
FDA notifications. FDA tentatively approves fixed-dose lamivudine/zidovudine.
    AIDS alert, 2010, Volume: 25, Issue:12

    Topics: Drug Approval; Drug Combinations; Drugs, Generic; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

2010
Validation of a sensitive LC/MS/MS method for the determination of zidovudine and lamivudine in human plasma.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:1

    Topics: Chromatography, Liquid; Drug Stability; Humans; Lamivudine; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Zidovudine

2012
Chronic action of association of zidovudine, lamivudine and ritonavir on pregnant rats. A biologic assay.
    Clinical and experimental obstetrics & gynecology, 2011, Volume: 38, Issue:1

    Topics: Animals; Animals, Newborn; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Body Weight; Female; Lamivudine; Litter Size; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Wistar; Ritonavir; Statistics, Nonparametric; Zidovudine

2011
FDA notifications. Fixed dose ART approved by FDA.
    AIDS alert, 2011, Volume: 26, Issue:3

    Topics: Dose-Response Relationship, Drug; Drug Approval; Drug Combinations; Humans; Lamivudine; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

2011
Improving retention in the early infant diagnosis of HIV program in rural Mozambique by better service integration.
    Journal of acquired immune deficiency syndromes (1999), 2011, Sep-01, Volume: 58, Issue:1

    Topics: Adult; Anti-HIV Agents; Delivery of Health Care; Drug Therapy, Combination; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mozambique; Nevirapine; Pregnancy; Retrospective Studies; Rural Population; Young Adult; Zidovudine

2011
Joint population pharmacokinetic analysis of zidovudine, lamivudine, and their active intracellular metabolites in HIV patients.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Adult; Anti-HIV Agents; Chromatography, Liquid; Cytidine Triphosphate; Dideoxynucleotides; Female; Humans; Lamivudine; Male; Middle Aged; Models, Theoretical; Sex Factors; Tandem Mass Spectrometry; Young Adult; Zidovudine

2011
Combination antiretroviral therapy as treatment for human immunodeficiency virus-associated mucosa-associated lymphoid tissue type lymphoma of the nasopharynx.
    Internal medicine journal, 2011, Volume: 41, Issue:5

    Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Humans; Lamivudine; Lopinavir; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Male; Middle Aged; Nasopharyngeal Neoplasms; Pyrimidinones; Radiotherapy, Adjuvant; Remission Induction; Ritonavir; Viral Load; Zidovudine

2011
Evaluation of saliva as an alternative matrix for monitoring plasma Zidovudine, Lamivudine and nevirapine concentrations in Rwanda.
    Current HIV research, 2011, Volume: 9, Issue:4

    Topics: Adult; Anti-HIV Agents; Cross-Sectional Studies; Drug Monitoring; Feasibility Studies; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Nevirapine; Rwanda; Saliva; Zidovudine

2011
[Comparative study of two anti-antiretroviral protocols used for treatment of a cohort of HIV 1-positive patients followed at the Institute of Public Health and Hygiene in Dakar, Senegal].
    Medecine tropicale : revue du Corps de sante colonial, 2011, Volume: 71, Issue:2

    Topics: Academies and Institutes; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; HIV Seropositivity; HIV-1; Humans; Hygiene; Lamivudine; Nevirapine; Public Health; Quality of Life; Retrospective Studies; Senegal; Survival Analysis; Treatment Outcome; Zidovudine

2011
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
    Journal of pharmaceutical and biomedical analysis, 2011, Sep-10, Volume: 56, Issue:2

    Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine; Diphosphates; Emtricitabine; Humans; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Organophosphonates; Phosphates; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Tenofovir; Zidovudine

2011
Prevention of mother-to-child transmission of HIV and the health-related Millennium Development Goals: time for a public health approach.
    Lancet (London, England), 2011, Jul-16, Volume: 378, Issue:9787

    Topics: Adult; Anti-HIV Agents; Breast Feeding; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; Female; Goals; Healthy People Programs; HIV Infections; HIV Seropositivity; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Malawi; Male; Nevirapine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Public Health; United Nations; Zidovudine

2011
[Coinfection with HIV and HCV: abacavir and ribavirine, why not?].
    Revista clinica espanola, 2012, Volume: 212, Issue:1

    Topics: Anti-HIV Agents; Antiviral Agents; Coinfection; Dideoxynucleosides; Drug Combinations; Drug Interactions; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Ribavirin; Zidovudine

2012
The effects of RNase H inhibitors and nevirapine on the susceptibility of HIV-1 to AZT and 3TC.
    Virology, 2011, Oct-25, Volume: 419, Issue:2

    Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Resistance, Viral; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Inhibitory Concentration 50; Lamivudine; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Ribonuclease H; Ribonuclease H, Human Immunodeficiency Virus; Zidovudine

2011
Characterization of thermal and rheological properties of zidovudine, lamivudine and plasticizer blends with ethyl cellulose to assess their suitability for hot melt extrusion.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Nov-20, Volume: 44, Issue:4

    Topics: Calorimetry, Differential Scanning; Cellulose; Chemistry, Pharmaceutical; Citrates; Delayed-Action Preparations; Lamivudine; Microscopy, Polarization; Phase Transition; Plasticizers; Polyethylene Glycols; Rheology; Solubility; Thermogravimetry; Transition Temperature; Viscosity; Zidovudine

2011
Management of needlestick injuries: a house officer who has a needlestick.
    JAMA, 2012, Jan-04, Volume: 307, Issue:1

    Topics: Anti-HIV Agents; Blood-Borne Pathogens; Drug Combinations; Emergency Service, Hospital; Health Personnel; HIV Infections; HIV Seropositivity; Humans; Internship and Residency; Lamivudine; Male; Needlestick Injuries; Occupational Exposure; Physicians; Post-Exposure Prophylaxis; Risk; United States; Zidovudine

2012
Successful treatment of aciclovir and foscarnet resistant Herpes simplex virus lesions with topical imiquimod in patients infected with human immunodeficiency virus type 1.
    Journal of medical virology, 2012, Volume: 84, Issue:2

    Topics: Acyclovir; Administration, Topical; Adult; Aminoquinolines; Antiviral Agents; Drug Resistance, Viral; Foscarnet; Herpes Simplex; HIV Infections; HIV-1; Humans; Imiquimod; Lamivudine; Male; Middle Aged; Nelfinavir; Simplexvirus; Zidovudine

2012
Pharmacokinetics of antiretroviral drug varies with formulation in the target population of children with HIV-1.
    Clinical pharmacology and therapeutics, 2012, Volume: 91, Issue:2

    Topics: Administration, Oral; Antirheumatic Agents; Chemistry, Pharmaceutical; Child, Preschool; Dideoxynucleosides; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Male; Solutions; Tablets; Therapeutic Equivalency; Zidovudine

2012
Costs and benefits of multidrug, multidose antiretroviral therapy for prevention of mother-to-child transmission of HIV in the Dominican Republic.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2012, Volume: 116, Issue:3

    Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cost-Benefit Analysis; Cyclopropanes; Dominican Republic; Drug Administration Schedule; Drug Costs; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Zidovudine

2012
Lopinavir/ritonavir trough concentrations with the tablet formulation in HIV-1-infected women during the third trimester of pregnancy.
    Scandinavian journal of infectious diseases, 2012, Volume: 44, Issue:5

    Topics: Adult; Anti-HIV Agents; Drug Combinations; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Reverse Transcriptase Inhibitors; Ritonavir; Tablets; Treatment Outcome; Young Adult; Zidovudine

2012
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5

    Topics: Acyclovir; Anti-HIV Agents; Cell Line; Drug Resistance, Viral; Drug Synergism; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Nevirapine; Palatine Tonsil; Protease Inhibitors; Ribavirin; T-Lymphocytes; Tissue Culture Techniques; Zidovudine

2012
Recombination between variants from genital tract and plasma: evolution of multidrug-resistant HIV type 1.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:12

    Topics: Adult; Anti-HIV Agents; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Nevirapine; Plasma; Recombination, Genetic; RNA, Viral; Sequence Analysis, DNA; Zidovudine

2012
Adverse drug reactions to antiretroviral therapy (ARVs): incidence, type and risk factors in Nigeria.
    BMC clinical pharmacology, 2012, Feb-27, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Organophosphonates; Pain; Retrospective Studies; Risk Factors; Stavudine; Tenofovir; Zidovudine

2012
Development and validation of an HPLC-UV method for simultaneous determination of zidovudine, lamivudine, and nevirapine in human plasma and its application to pharmacokinetic study in human volunteers.
    Drug testing and analysis, 2013, Volume: 5, Issue:6

    Topics: Anti-HIV Agents; Chromatography, High Pressure Liquid; Humans; Lamivudine; Limit of Detection; Liquid-Liquid Extraction; Nevirapine; Zidovudine

2013
Emergence of minor drug-resistant HIV-1 variants after triple antiretroviral prophylaxis for prevention of vertical HIV-1 transmission.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Adult; Alleles; Anti-Retroviral Agents; Drug Resistance, Viral; Female; Genetic Variation; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nevirapine; Oligonucleotides; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Tanzania; Zidovudine

2012
Effect of HIV-1 infection and sex on the cellular pharmacology of the antiretroviral drugs zidovudine and lamivudine.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Adult; Anti-HIV Agents; Black or African American; Cytidine Triphosphate; Dideoxynucleotides; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Prospective Studies; Sex Factors; Thymine Nucleotides; Zidovudine

2012
Comparative studies of lamivudine-zidovudine nanoparticles for the selective uptake by macrophages.
    Current drug delivery, 2012, Volume: 9, Issue:5

    Topics: Animals; Anti-HIV Agents; Drug Carriers; Drug Combinations; Lactic Acid; Lamivudine; Lipids; Macrophages; Male; Mice; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polysorbates; Reverse Transcriptase Inhibitors; Surface-Active Agents; Tissue Distribution; Zidovudine

2012
Simultaneous determination of lamivudine, lopinavir, ritonavir, and zidovudine concentration in plasma of HIV-infected patients by HPLC-MS/MS.
    IUBMB life, 2012, Volume: 64, Issue:5

    Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; HIV Infections; Humans; Lamivudine; Limit of Detection; Lopinavir; Reference Standards; Reproducibility of Results; Ritonavir; Tandem Mass Spectrometry; Zidovudine

2012
Impact of short-term HAART initiated during the chronic stage or shortly post-exposure on SIV infection of male genital organs.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Animals; Antiretroviral Therapy, Highly Active; Genitalia, Male; Indinavir; Lamivudine; Macaca fascicularis; Male; RNA, Viral; Semen; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Viral Load; Zidovudine

2012
Response to valacyclovir in an HIV-infected girl with Epstein Barr infection.
    Indian pediatrics, 2012, Volume: 49, Issue:5

    Topics: Acyclovir; Alkynes; Antiretroviral Therapy, Highly Active; Antiviral Agents; Benzoxazines; Child; Cyclopropanes; Epstein-Barr Virus Infections; Female; HIV Infections; Humans; Lamivudine; Valacyclovir; Valine; Zidovudine

2012
Evaluation of different antiretroviral drug protocols on naturally infected feline immunodeficiency virus (FIV) cats in the late phase of the asymptomatic stage of infection.
    Viruses, 2012, Volume: 4, Issue:6

    Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cat Diseases; Cats; CD4-CD8 Ratio; Evoked Potentials, Auditory; Evoked Potentials, Visual; Feline Acquired Immunodeficiency Syndrome; Female; Interferon-alpha; Lamivudine; Male; Treatment Outcome; Viral Load; Zidovudine

2012
Trends in HIV-1 reverse transcriptase resistance-associated mutations and antiretroviral prescription data from 2003-2010.
    Antiviral therapy, 2012, Volume: 17, Issue:6

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Prescriptions; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Prevalence; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Zidovudine

2012
Monitoring of HAART regime antiretrovirals in serum of acquired immunodeficiency syndrome patients by micellar liquid chromatography.
    The Analyst, 2012, Sep-21, Volume: 137, Issue:18

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Chromatography, Liquid; Cyclopropanes; Drug Monitoring; Humans; Lamivudine; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012
Evaluating the cost-effectiveness of combination antiretroviral therapy for the prevention of mother-to-child transmission of HIV in Uganda.
    Bulletin of the World Health Organization, 2012, Aug-01, Volume: 90, Issue:8

    Topics: Anti-HIV Agents; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Uganda; Zidovudine

2012
Differential in vitro kinetics of drug resistance mutation acquisition in HIV-1 RT of subtypes B and C.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Anti-HIV Agents; Cell Line; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Zidovudine

2012
Thymidine analogues suppress autophagy and adipogenesis in cultured adipocytes.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:1

    Topics: Adipocytes; Adipogenesis; Androstadienes; Animals; Autophagy; Autophagy-Related Protein 5; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Chromones; Flow Cytometry; Humans; Lamivudine; Mice; Microscopy, Fluorescence; Microtubule-Associated Proteins; Mitochondria; Morpholines; Nocodazole; Phagosomes; Reverse Transcriptase Inhibitors; RNA, Small Interfering; Stavudine; Wortmannin; Zidovudine

2013
Synergistic antivirus effect of combined administration of Combivir with Angelica polysaccharide sulfate.
    International journal of biological macromolecules, 2013, Volume: 53

    Topics: Animals; Anti-HIV Agents; Bone Marrow Cells; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Humans; Lamivudine; Lethal Dose 50; Leukemia Virus, Murine; Mice; Mice, Inbred BALB C; Organ Size; Polysaccharides; Thymus Gland; Viral Load; Virus Replication; Zidovudine

2013
[Acute hemolytic anemia in an HIV patient after inhalation of amyl nitrite].
    Medecine et maladies infectieuses, 2012, Volume: 42, Issue:12

    Topics: Administration, Inhalation; Adult; Amyl Nitrite; Anemia, Hemolytic; Anti-HIV Agents; Diagnosis, Differential; Dideoxynucleosides; HIV Infections; Humans; Illicit Drugs; Inhalant Abuse; Iraq; Lamivudine; Male; Travel; Zidovudine

2012
Impact of hepatitis C virus on HIV response to antiretroviral therapy in Nigeria.
    Journal of acquired immune deficiency syndromes (1999), 2013, Feb-01, Volume: 62, Issue:2

    Topics: Adult; Alanine Transaminase; Alkynes; Anti-Retroviral Agents; Benzoxazines; Chemical and Drug Induced Liver Injury; Coinfection; Cyclopropanes; Deoxycytidine; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Nevirapine; Nigeria; Organophosphorus Compounds; RNA, Viral; Stavudine; Zidovudine

2013
[A case of vitiligo occurring after initiation of antiretroviral treatment and disappearing during this treatment: autoimmune IRIS syndrome?].
    Annales de dermatologie et de venereologie, 2012, Volume: 139, Issue:11

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Follow-Up Studies; HIV Seropositivity; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Male; Viral Load; Vitiligo; Zidovudine

2012
Comparative analysis of genetic toxicity of antiretroviral combinations in somatic cells of Drosophila melanogaster.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA Damage; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Combinations; Female; Lamivudine; Male; Mitosis; Mutation; Recombinant Proteins; Wings, Animal; Zidovudine

2013
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
    The Journal of infectious diseases, 2013, Volume: 207, Issue:7

    Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cells, Cultured; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Enzyme Activation; Female; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Regression Analysis; Reverse Transcriptase Inhibitors; Risk Factors; Telomerase; Telomere; Telomere Shortening; Tenofovir; Time Factors; Young Adult; Zidovudine

2013
Risk adapted transmission prophylaxis to prevent vertical HIV-1 transmission: effectiveness and safety of an abbreviated regimen of postnatal oral zidovudine.
    BMC pregnancy and childbirth, 2013, Jan-24, Volume: 13

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Risk Factors; Treatment Outcome; Zidovudine

2013
Toxicology and carcinogenesis studies of mixtures of 3'-azido-3'-deoxythymidine (AZT), lamivudine (3TC), nevirapine (NVP), and nelfinavir mesylate (NFV) (Cas Nos. 30516-87-1, 134678-17-4, 129618-40-2, 159989-65-8) in B6C3F1 Mice (transplacental exposure s
    National Toxicology Program technical report series, 2013, Issue:569

    Topics: Administration, Oral; Animals; Anti-Retroviral Agents; DNA; Drug Therapy, Combination; Escherichia coli; Female; Lamivudine; Longevity; Male; Maternal Exposure; Mice; Mice, Inbred Strains; Nelfinavir; Nevirapine; Pregnancy; Prenatal Exposure Delayed Effects; Salmonella typhimurium; Skin Neoplasms; Zidovudine

2013
High throughput LC-MS/MS method for simultaneous determination of zidovudine, lamivudine and nevirapine in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Mar-15, Volume: 921-922

    Topics: Anti-HIV Agents; Chromatography, Liquid; Humans; Lamivudine; Male; Nevirapine; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Zidovudine

2013
Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion.
    AIDS (London, England), 2013, Jun-01, Volume: 27, Issue:9

    Topics: Anti-HIV Agents; Calcitriol; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Female; HIV Reverse Transcriptase; Humans; Infant; Lamivudine; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Myoblasts; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Vitamins; Zidovudine

2013
Tropical spastic paraparesis treated with Combivir (lamivudine-zidovudine).
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013, Volume: 20, Issue:5

    Topics: Aged; Drug Combinations; Female; Human T-lymphotropic virus 1; Humans; Lamivudine; Paraparesis, Tropical Spastic; Severity of Illness Index; Treatment Outcome; Zidovudine

2013
The stress response resolution assay. II. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.
    Environmental and molecular mutagenesis, 2013, Volume: 54, Issue:4

    Topics: Amphotericin B; Animals; Cell Cycle Checkpoints; Cell Death; Cell Line; Cell Proliferation; Cell Shape; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Ethylnitrosourea; Guanine Nucleotides; Humans; Hypoxanthine Phosphoribosyltransferase; Lamivudine; Mice; Mutagens; Mutation; Phenotype; Stress, Physiological; Thionucleotides; Toxicity Tests; Zidovudine

2013
The stress response resolution assay. I. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.
    Environmental and molecular mutagenesis, 2013, Volume: 54, Issue:4

    Topics: Amphotericin B; Animals; Calibration; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Pollutants; Epithelial Cells; Epithelium; Ethylnitrosourea; Guanine Nucleotides; Humans; Lamivudine; Mice; Mutagens; Stress, Physiological; Thionucleotides; Toxicity Tests; Zidovudine

2013
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
    Lipids in health and disease, 2013, Apr-10, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine

2013
Talk of HIV cure goes viral.
    The Lancet. Infectious diseases, 2013, Volume: 13, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Child, Preschool; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Male; Nevirapine; Primary Prevention; Ritonavir; Secondary Prevention; Time Factors; Zidovudine

2013
Left ventricular hypertrophy detected by echocardiography in HIV-infected patients.
    European journal of internal medicine, 2013, Volume: 24, Issue:6

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Carbamates; Comorbidity; Cross-Sectional Studies; Cyclopropanes; Diabetes Mellitus; Drug Combinations; Dyslipidemias; Echocardiography; Female; Furans; HIV Infections; Humans; Hypertension; Hypertrophy, Left Ventricular; Lamivudine; Lopinavir; Male; Middle Aged; Nevirapine; Organophosphates; Organophosphonates; Risk Factors; Ritonavir; Smoking; Spain; Sulfonamides; Tenofovir; Zidovudine

2013
Antiretroviral drugs in Africa: a public health versus a market approach.
    Journal of acquired immune deficiency syndromes (1999), 2013, Jun-01, Volume: 63, Issue:2

    Topics: Africa; Anti-HIV Agents; Drug Packaging; Health Resources; Health Services Accessibility; HIV Infections; Humans; Lamivudine; Nevirapine; Public Health; Zidovudine

2013
Drug-resistance development differs between HIV-1-infected patients failing first-line antiretroviral therapy containing nonnucleoside reverse transcriptase inhibitors with and without thymidine analogues.
    HIV medicine, 2013, Volume: 14, Issue:9

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Tenofovir; Thymidine; Treatment Failure; Viral Load; Zidovudine

2013
Characterization of antiviral activity of benzamide derivative AH0109 against HIV-1 infection.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:8

    Topics: Active Transport, Cell Nucleus; CD4-Positive T-Lymphocytes; DNA, Viral; Drug Evaluation, Preclinical; HEK293 Cells; HIV Integrase Inhibitors; HIV-1; Humans; Lamivudine; Microbial Sensitivity Tests; Morphinans; Nevirapine; Reverse Transcriptase Inhibitors; Reverse Transcription; Virus Replication; Zidovudine

2013
Baseline CD4 cell counts and outcomes among adult treatment naive HIV patients after taking fixed dose combination GPO-VIR-S and GPO-VIR-Z in Thailand.
    The Southeast Asian journal of tropical medicine and public health, 2013, Volume: 44, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Female; Hematologic Tests; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Kaplan-Meier Estimate; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Thailand; Treatment Outcome; Viral Load; Zidovudine

2013
Economic evaluation of 3-drug antiretroviral regimens for the prevention of mother-to-child HIV transmission in Thailand.
    Asia-Pacific journal of public health, 2015, Volume: 27, Issue:2

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cost-Benefit Analysis; Cyclopropanes; Drug Therapy, Combination; Female; Health Services; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Models, Econometric; Mothers; Nevirapine; Pregnancy; Thailand; Zidovudine

2015
Adherence to antiretroviral therapy among HIV infected children measured by caretaker report, medication return, and drug level in Dar Es Salaam, Tanzania.
    BMC pediatrics, 2013, Jun-15, Volume: 13

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Caregivers; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Drug Administration Schedule; Drug Combinations; Female; HIV Infections; Humans; Lamivudine; Logistic Models; Male; Medication Adherence; Middle Aged; Nevirapine; Odds Ratio; Stavudine; Surveys and Questionnaires; Tanzania; Young Adult; Zidovudine

2013
Clinical experience of raltegravir with abacavir/lamivudine or zidovudine/lamivudine in HIV-infected Korean adults.
    Japanese journal of infectious diseases, 2013, Volume: 66, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Humans; Lamivudine; Lipids; Male; Middle Aged; Prospective Studies; Pyrrolidinones; Raltegravir Potassium; Republic of Korea; Retrospective Studies; Treatment Outcome; Viral Load; Young Adult; Zidovudine

2013
HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Resistance, Viral; Epidemiological Monitoring; Female; Ghana; HIV Infections; HIV Protease; HIV-1; Humans; Infant; Lamivudine; Male; Middle Aged; Molecular Epidemiology; Molecular Typing; Mutation, Missense; Nevirapine; Prevalence; Sequence Analysis, DNA; Stavudine; Zidovudine

2013
Anemia and risk factors in HAART naïve and HAART experienced HIV positive persons in south west Ethiopia: a comparative study.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Anemia; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Cross-Sectional Studies; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nevirapine; Risk Factors; Social Class; Surveys and Questionnaires; Zidovudine

2013
High-levels of acquired drug resistance in adult patients failing first-line antiretroviral therapy in a rural HIV treatment programme in KwaZulu-Natal, South Africa.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Alkynes; Analysis of Variance; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Outcome Assessment, Health Care; Prevalence; South Africa; Stavudine; Young Adult; Zidovudine

2013
Child cured of HIV: can this be repeated?
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:17

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Infant, Newborn; Lamivudine; Nevirapine; Reverse Transcriptase Inhibitors; Zidovudine

2013
[Evaluation of tolerance of zidovudine-lamivudine-nevirapine combination in HIV 1 patients in Fann Teaching Hospital in Dakar].
    Bulletin de la Societe de pathologie exotique (1990), 2013, Volume: 106, Issue:4

    Topics: Adult; Anti-HIV Agents; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; HIV-1; Hospitals, Teaching; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Senegal; Zidovudine

2013
Continuous wavelet transforms for the simultaneous quantitative analysis and dissolution testing of lamivudine-zidovudine tablets.
    Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:12

    Topics: Anti-HIV Agents; Drug Combinations; Lamivudine; Solubility; Tablets; Wavelet Analysis; Zidovudine

2013
Trends in clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Shanghai from 2006 to 2011.
    International journal of STD & AIDS, 2014, Volume: 25, Issue:7

    Topics: Adolescent; Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; China; Cross-Sectional Studies; Female; HIV Infections; Humans; Immune Tolerance; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Stavudine; Viral Load; Zidovudine

2014
Preliminary study of quinine pharmacokinetics in pregnant women with malaria-HIV co-infection.
    The American journal of tropical medicine and hygiene, 2014, Volume: 90, Issue:3

    Topics: Adult; Anti-HIV Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Coinfection; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria, Falciparum; Nevirapine; Parasite Load; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Quinidine; Quinine; Stavudine; Treatment Outcome; Young Adult; Zidovudine

2014
Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapy.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Amodiaquine; Anti-Retroviral Agents; Antimalarials; Antiretroviral Therapy, Highly Active; Artemisinins; Artesunate; Chromatography, High Pressure Liquid; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Malaria; Male; Middle Aged; Nevirapine; Nigeria; Plasma; Young Adult; Zidovudine

2014
Long-term exposure of mice to nucleoside analogues disrupts mitochondrial DNA maintenance in cortical neurons.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Antimetabolites; Cells, Cultured; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Liver; Mice; Mitochondria; Muscle, Skeletal; Neurons; Stavudine; Zidovudine

2014
Clinical profile and response to first-line ARV in HIV patients from Eastern UP and Bihar: a retrospective study.
    The Journal of the Association of Physicians of India, 2013, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Female; HIV Infections; Humans; India; Lamivudine; Male; Middle Aged; Nevirapine; Retrospective Studies; Reverse Transcriptase Inhibitors; Stavudine; Treatment Outcome; Young Adult; Zidovudine

2013
Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adult; Alkynes; Area Under Curve; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoxazines; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genotype; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Mutation; Pharmacogenetics; Reverse Transcriptase Inhibitors; Treatment Outcome; Uganda; Zidovudine

2014
Toxicology and Carcinogenesis Studies of Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine (3TC), and Nevirapine (NVP) (CAS Nos. 30516-87-1, 134678-17-4, 129618-40-2) in Genetically Modified C3B6.129F1-Trp53(tm1Brd) N12 Haploinsufficient Mice (in u
    National Toxicology Program genetically modified model report, 2013, Issue:16

    Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Anti-HIV Agents; Body Weight; Chemistry, Pharmaceutical; Drug Combinations; Female; Haploinsufficiency; Intubation, Gastrointestinal; Lamivudine; Litter Size; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Nevirapine; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Reverse Transcriptase Inhibitors; Survival; Zidovudine

2013
Hepatitis B and C co-infection among HIV-infected adults while on antiretroviral treatment: long-term survival, CD4 cell count recovery and antiretroviral toxicity in Cambodia.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Cambodia; CD4 Lymphocyte Count; Coinfection; Cyclopropanes; Female; Hepatitis B; Hepatitis C; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Liver; Logistic Models; Male; Middle Aged; Nevirapine; Proportional Hazards Models; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine

2014
Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.
    Journal of neurovirology, 2014, Volume: 20, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Case-Control Studies; Drug Combinations; Drug Therapy, Combination; Genome-Wide Association Study; Genotype; Humans; Lamivudine; Multicenter Studies as Topic; Peripheral Nervous System Diseases; Polymorphism, Genetic; Principal Component Analysis; Randomized Controlled Trials as Topic; Retrospective Studies; Stavudine; Treatment Outcome; Zidovudine

2014
Challenges of antiretroviral treatment monitoring in rural and remote-access regions in Africa.
    AIDS research and human retroviruses, 2014, Volume: 30, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Africa; Alkynes; Anti-HIV Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Drug Monitoring; Drug Resistance, Viral; Female; HIV-1; Hospitals, Rural; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Rural Health Services; Rural Population; Stavudine; Treatment Outcome; Zidovudine

2014
New dinucleoside phosphonate derivatives as prodrugs of 3'-azido-3'-deoxythymidine and β-L-2',3'-dideoxy-3'-thiacytidine: synthesis and anti-HIV properties.
    Nucleosides, nucleotides & nucleic acids, 2014, Volume: 33, Issue:2

    Topics: Anti-HIV Agents; Cell Line; Drug Stability; HIV-1; Humans; Hydrolysis; Lamivudine; Microbial Sensitivity Tests; Nuclear Magnetic Resonance, Biomolecular; Prodrugs; Zidovudine

2014
The financial and service implications of splitting fixed-dose antiretroviral drugs - a case study.
    International journal of STD & AIDS, 2015, Volume: 26, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Cost-Benefit Analysis; Costs and Cost Analysis; Drug Combinations; Drug Substitution; Female; Health Care Costs; HIV Infections; Humans; Lamivudine; Male; Treatment Outcome; Viral Load; Zidovudine

2015
Spectra resolution for simultaneous spectrophotometric determination of lamivudine and zidovudine components in pharmaceutical formulation of human immunodeficiency virus drug based on using continuous wavelet transform and derivative transform techniques
    Talanta, 2014, Volume: 122

    Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Combinations; Lamivudine; Spectrophotometry, Ultraviolet; Wavelet Analysis; Zidovudine

2014
Presence of HIV drug resistance in antiretroviral therapy-naive and -experienced patients from Papua New Guinea.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dried Blood Spot Testing; Drug Resistance, Viral; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Papua New Guinea; Reverse Transcriptase Inhibitors; Stavudine; Treatment Failure; Viral Load; Young Adult; Zidovudine

2014
Clinical manifestations and treatment outcomes in HIV-1-infected children receiving antiretroviral therapy in Karachi, Pakistan.
    Journal of infection in developing countries, 2014, Apr-15, Volume: 8, Issue:4

    Topics: Anti-HIV Agents; Body Height; Body Weight; CD4 Lymphocyte Count; Child, Preschool; Drug Resistance, Viral; Female; Genotype; HIV; HIV Infections; Humans; Infant; Lamivudine; Male; Nevirapine; Pakistan; Retrospective Studies; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load; Zidovudine

2014
Sustained increase of serum creatine phosphokinase levels and progressive muscle abnormalities associated with raltegravir use during 32-week follow-up in an HIV-1 experienced patient on simplified HAART regimen, intolerant to protease inhibitors and abac
    The West Indian medical journal, 2013, Volume: 62, Issue:4

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Creatine Kinase; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Muscle Weakness; Myalgia; Pyrrolidinones; Raltegravir Potassium; Zidovudine

2013
Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND).
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Alkynes; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Benzoxazines; Cell Line; Cognition Disorders; Cyclopropanes; Female; HIV Infections; Humans; Lamivudine; Mice; Oxidative Stress; Phagocytosis; Reverse Transcriptase Inhibitors; Zidovudine

2014
Extensive pulmonary involvement with raltegravir-induced DRESS syndrome in a postpartum woman with HIV.
    BMJ case reports, 2014, May-05, Volume: 2014

    Topics: Adolescent; Anti-HIV Agents; Drug Combinations; Drug Hypersensitivity Syndrome; Female; HIV Infections; HIV Integrase Inhibitors; Humans; Lamivudine; Lopinavir; Pleural Effusion; Postpartum Period; Pyrrolidinones; Radiography; Raltegravir Potassium; Respiratory Distress Syndrome; Ritonavir; Zidovudine

2014
MicroRNA-150 is a potential biomarker of HIV/AIDS disease progression and therapy.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; CD4 Lymphocyte Count; Cyclopropanes; Disease Progression; Drug Resistance, Viral; Female; Gene Expression Regulation; HIV; Humans; Lamivudine; Leukocytes, Mononuclear; Male; MicroRNAs; Nevirapine; Stavudine; Treatment Outcome; Viral Load; Zidovudine

2014
SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Adenine; Cell Line; Dideoxynucleotides; Gene Expression; Genes, Reporter; HIV Reverse Transcriptase; HIV-1; Host-Pathogen Interactions; Humans; Lamivudine; Luciferases; Monocytes; Monomeric GTP-Binding Proteins; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; SAM Domain and HD Domain-Containing Protein 1; Stavudine; Tenofovir; Virus Replication; Zidovudine

2014
Impact of Y181C and/or H221Y mutation patterns of HIV-1 reverse transcriptase on phenotypic resistance to available non-nucleoside and nucleoside inhibitors in China.
    BMC infectious diseases, 2014, May-05, Volume: 14

    Topics: Alkynes; Benzoxazines; China; Cyclopropanes; Drug Resistance, Multiple, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Nevirapine; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2014
A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.
    Antiviral research, 2014, Volume: 109

    Topics: Anti-HIV Agents; Dideoxynucleotides; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Humans; In Vitro Techniques; Lamivudine; Palatine Tonsil; Thymine Nucleotides; Virus Replication; Zidovudine

2014
Side effects and tolerability of post-exposure prophylaxis with zidovudine, lamivudine, and lopinavir/ritonavir: a comparative study with HIV/AIDS patients.
    Chinese medical journal, 2014, Volume: 127, Issue:14

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; HIV Infections; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Post-Exposure Prophylaxis; Retrospective Studies; Ritonavir; Zidovudine

2014
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine

2014
Pure red cell aplasia induced by lamivudine without the influence of zidovudine in a patient infected with human immunodeficiency virus.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:15

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Biopsy, Needle; Bone Marrow; Diagnosis, Differential; HIV Infections; Humans; Lamivudine; Male; Platelet Count; Red-Cell Aplasia, Pure; Young Adult; Zidovudine

2014
Overexpression of mitochondrial antioxidant manganese superoxide dismutase (MnSOD) provides protection against AZT- or 3TC-induced endothelial dysfunction.
    Antiviral research, 2014, Volume: 111

    Topics: Animals; Anti-HIV Agents; Antioxidants; Aorta, Thoracic; Female; HIV Infections; Humans; Lamivudine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Superoxide Dismutase; Zidovudine

2014
Lopinavir/ritonavir plus lamivudine and abacavir or zidovudine dose ratios for paediatric fixed-dose combinations.
    Antiviral therapy, 2015, Volume: 20, Issue:2

    Topics: Administration, Oral; Adolescent; Age Factors; Antiretroviral Therapy, Highly Active; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic; Computer Simulation; Dideoxynucleosides; Drug Combinations; Drug Dosage Calculations; Drug Monitoring; Female; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Male; Models, Statistical; Ritonavir; Silybin; Silymarin; Viral Load; Zidovudine

2015
Impact of combination antiretroviral therapy in the NOD.c3c4 mouse model of autoimmune biliary disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:4

    Topics: Amino Acid Sequence; Animals; Anti-Retroviral Agents; Biomarkers; Cholangitis; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; Lamivudine; Liver Cirrhosis, Biliary; Lopinavir; Mammary Tumor Virus, Mouse; Mice, Inbred NOD; Molecular Sequence Data; Protease Inhibitors; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Time Factors; Tumor Virus Infections; Viral Load; Zidovudine

2015
Persistent production of an integrase-deleted HIV-1 variant with no resistance mutation and wild-type proviral DNA in a treated patient.
    AIDS research and human retroviruses, 2015, Volume: 31, Issue:1

    Topics: Anti-HIV Agents; Base Sequence; Defective Viruses; DNA, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Immune Evasion; Integrases; Lamivudine; Leukocytes, Mononuclear; Lopinavir; Molecular Sequence Data; Proviruses; Sequence Analysis, DNA; Sequence Deletion; Viral Load; Zidovudine

2015
Human immunodeficiency virus post-exposure prophylaxis: primum non nocere.
    The American journal of medicine, 2015, Volume: 128, Issue:4

    Topics: Adult; Antiviral Agents; Bipolar Disorder; Cytochrome P-450 CYP3A Inhibitors; Dihydroergotamine; Drug Synergism; Drug Therapy, Combination; Ergotism; Female; HIV Infections; Humans; Hypotension, Orthostatic; Lamivudine; Lopinavir; Post-Exposure Prophylaxis; Ritonavir; Vasoconstrictor Agents; Zidovudine

2015
Is zidovudine first-line therapy virologically comparable to tenofovir in resource-limited settings?
    Tropical medicine & international health : TM & IH, 2015, Volume: 20, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; Health Resources; HIV; HIV Infections; Humans; Lamivudine; Lesotho; Logistic Models; Male; Middle Aged; Organophosphonates; Tenofovir; Viral Load; Zidovudine

2015
Follow-up on long-term antiretroviral therapy for cats infected with feline immunodeficiency virus.
    Journal of feline medicine and surgery, 2016, Volume: 18, Issue:4

    Topics: Animals; Cat Diseases; Cats; CD8-Positive T-Lymphocytes; Feline Acquired Immunodeficiency Syndrome; Follow-Up Studies; Immunodeficiency Virus, Feline; Lamivudine; Molecular Sequence Data; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2016
[Analysis on HIV suppression effect after initiating antiretroviral treatment and related factors among AIDS patients in Henan province during 2008 and 2013].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2015, Volume: 49, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Female; Health Facilities; HIV Infections; Humans; Lamivudine; Male; Nevirapine; Stavudine; Time-to-Treatment; Treatment Outcome; Zidovudine

2015
Time trends of baseline demographics and clinical characteristics of HIV infected children enrolled in care and treatment service in Dar es Salaam, Tanzania.
    BMC infectious diseases, 2015, Mar-26, Volume: 15

    Topics: Adolescent; Age Distribution; Alkynes; Ambulatory Care Facilities; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Comorbidity; Cyclopropanes; Female; HIV Infections; Humans; Infant; Lamivudine; Linear Models; Male; Nevirapine; Severity of Illness Index; Tanzania; Tuberculosis; Zidovudine

2015
Progress Toward Eliminating Mother to Child Transmission of HIV in Kenya: Review of Treatment Guideline Uptake and Pediatric Transmission at Four Government Hospitals Between 2010 and 2012.
    AIDS and behavior, 2016, Volume: 20, Issue:11

    Topics: Adult; Anti-HIV Agents; Child; Cohort Studies; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Early Diagnosis; Female; Gestational Age; Government; Guideline Adherence; HIV Infections; Hospitals, Public; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Kenya; Lamivudine; Medication Adherence; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Zidovudine

2016
[Comparative and evolutionary profile of people infected with HIV on antiretroviral therapy in Kinshasa, Democratic Republic of Congo].
    The Pan African medical journal, 2014, Volume: 19

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Democratic Republic of the Congo; Disease Progression; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Ritonavir; Zidovudine

2014
Serious adverse events are uncommon with combination neonatal antiretroviral prophylaxis: a retrospective case review.
    PloS one, 2015, Volume: 10, Issue:5

    Topics: Anemia; Anti-HIV Agents; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Neutropenia; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Thrombocytopenia; Zidovudine

2015
Mitochondrial DNA D-loop AG/TC transition mutation in cortical neurons of mice after long-term exposure to nucleoside analogues.
    Journal of neurovirology, 2015, Volume: 21, Issue:5

    Topics: Animals; Cerebral Cortex; Didanosine; DNA, Mitochondrial; Lamivudine; Laser Capture Microdissection; Mice; Mice, Inbred BALB C; Mutation; Neurons; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2015
Comparative Application of PLS and PCR Methods to Simultaneous Quantitative Estimation and Simultaneous Dissolution Test of Zidovudine - Lamivudine Tablets.
    Acta chimica Slovenica, 2015, Volume: 62, Issue:2

    Topics: Anti-HIV Agents; Drug Combinations; Lamivudine; Least-Squares Analysis; Principal Component Analysis; Reverse Transcriptase Inhibitors; Solubility; Tablets; Zidovudine

2015
Adverse events and adherence to HIV post-exposure prophylaxis: a cohort study at the Korle-Bu Teaching Hospital in Accra, Ghana.
    BMC public health, 2015, Jun-20, Volume: 15

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Drug Combinations; Female; Ghana; HIV Infections; Hospitals, Teaching; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Male; Middle Aged; Occupational Exposure; Post-Exposure Prophylaxis; Young Adult; Zidovudine

2015
Pharmacokinetic Modeling of Lamivudine and Zidovudine Triphosphates Predicts Differential Pharmacokinetics in Seminal Mononuclear Cells and Peripheral Blood Mononuclear Cells.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: Adult; Anti-HIV Agents; Biological Availability; Biological Transport; Blood Cells; Computer Simulation; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Models, Statistical; Semen; Thymine Nucleotides; Time Factors; Zidovudine

2015
Prevalence of drug resistance mutations in HAART patients infected with HIV-1 CRF06_cpx in Estonia.
    Journal of medical virology, 2016, Volume: 88, Issue:3

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Didanosine; Dideoxynucleosides; Drug Resistance, Viral; Estonia; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Prevalence; Reverse Transcriptase Inhibitors; Zidovudine

2016
Photolysis of three antiviral drugs acyclovir, zidovudine and lamivudine in surface freshwater and seawater.
    Chemosphere, 2015, Volume: 138

    Topics: Acyclovir; Antiviral Agents; Fresh Water; Lamivudine; Models, Theoretical; Nitrates; Oxidation-Reduction; Photolysis; Risk Assessment; Seawater; Sunlight; Water Pollutants, Chemical; Zidovudine

2015
Longitudinal Analysis of Adherence to First-Line Antiretroviral Therapy: Evidence of Treatment Sustainability from an Indian HIV Cohort.
    Current HIV research, 2016, Volume: 14, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Administration Schedule; Female; HIV Infections; Humans; India; Lamivudine; Longitudinal Studies; Male; Medication Adherence; Middle Aged; Nevirapine; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine

2016
Role of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine.
    Biopharmaceutics & drug disposition, 2016, Volume: 37, Issue:1

    Topics: Acridines; Animals; Anti-HIV Agents; ATP-Binding Cassette Transporters; Dogs; Drug Interactions; Female; In Vitro Techniques; Indomethacin; Lamivudine; Madin Darby Canine Kidney Cells; Multidrug Resistance-Associated Protein 2; Placenta; Pregnancy; Rats, Wistar; Tetrahydroisoquinolines; Zidovudine

2016
Which Clinician Questions Elicit Accurate Disclosure of Antiretroviral Non-adherence When Talking to Patients?
    AIDS and behavior, 2016, Volume: 20, Issue:5

    Topics: Adult; Anti-HIV Agents; Attitude of Health Personnel; Communication; Disclosure; Drug Combinations; Female; HIV Infections; Humans; Interviews as Topic; Lamivudine; Male; Medication Adherence; Middle Aged; Office Visits; Patient Care; Physician-Patient Relations; Zidovudine

2016
Effect of abacavir on sustained virologic response to HCV treatment in HIV/HCV co-infected patients, Cohere in Eurocoord.
    BMC infectious diseases, 2015, Nov-04, Volume: 15

    Topics: Adult; Anti-HIV Agents; Cohort Studies; Coinfection; Dideoxynucleosides; Drug Combinations; Emtricitabine; Europe; Female; Hepacivirus; Hepatitis C; HIV Infections; Humans; Interferon-alpha; Lamivudine; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribavirin; Tenofovir; Zidovudine

2015
Adherence to Post-Exposure Prophylaxis (PEP) and Incidence of HIV Seroconversion in a Major North American Cohort.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Adolescent; Adult; Aged; Anti-HIV Agents; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV Seropositivity; Humans; Incidence; Lamivudine; Lopinavir; Male; Medication Adherence; Middle Aged; Post-Exposure Prophylaxis; Quebec; Ritonavir; Tenofovir; Young Adult; Zidovudine

2015
Nanogel-Conjugated Reverse Transcriptase Inhibitors and Their Combinations as Novel Antiviral Agents with Increased Efficacy against HIV-1 Infection.
    Molecular pharmaceutics, 2015, Dec-07, Volume: 12, Issue:12

    Topics: Animals; Anti-HIV Agents; Dideoxynucleosides; Drug Therapy, Combination; Hep G2 Cells; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mice; Nanogels; Polyethylene Glycols; Polyethyleneimine; Polylysine; Reverse Transcriptase Inhibitors; Zidovudine

2015
Plasma Mitochondrial DNA Levels as a Biomarker of Lipodystrophy Among HIV-infected Patients Treated with Highly Active Antiretroviral Therapy (HAART).
    Current molecular medicine, 2015, Volume: 15, Issue:10

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Biomarkers; Case-Control Studies; Cyclopropanes; DNA, Mitochondrial; Drug Combinations; Female; HIV; HIV Infections; Humans; Lamivudine; Lipodystrophy; Lopinavir; Male; Middle Aged; Mitochondria; Nelfinavir; Predictive Value of Tests; Ritonavir; ROC Curve; Stavudine; Zidovudine

2015
Low Prolactin and High 20-α-Hydroxysteroid Dehydrogenase Levels Contribute to Lower Progesterone Levels in HIV-Infected Pregnant Women Exposed to Protease Inhibitor-Based Combination Antiretroviral Therapy.
    The Journal of infectious diseases, 2016, May-15, Volume: 213, Issue:10

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; Animals; Anti-HIV Agents; Cells, Cultured; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Mice; Mice, Inbred C57BL; Placenta; Pregnancy; Pregnancy Complications, Infectious; Progesterone; Prolactin; Ritonavir; Trophoblasts; Zidovudine

2016
Improved pregnancy outcomes with increasing antiretroviral coverage in South Africa.
    BMC pregnancy and childbirth, 2016, Feb-11, Volume: 16

    Topics: Adolescent; Adult; Anti-Retroviral Agents; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Prenatal Care; South Africa; Stavudine; Young Adult; Zidovudine

2016
Hyaluronic Acid-Based Biocompatible Supramolecular Assembly for Sustained Release of Antiretroviral Drug.
    Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:9

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; beta-Cyclodextrins; Biocompatible Materials; Cells, Cultured; Delayed-Action Preparations; Drug Delivery Systems; HIV-1; Humans; Hyaluronic Acid; Lamivudine; Polylysine; Zidovudine

2016
CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population.
    Pharmacogenomics, 2016, Volume: 17, Issue:6

    Topics: Adult; Africa South of the Sahara; Alkynes; Anti-HIV Agents; Antitubercular Agents; Benzoxazines; Coinfection; Cyclopropanes; Cytochrome P-450 CYP2B6; Female; Genotype; HIV Infections; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; Rifampin; Tuberculosis; Viral Load; Zidovudine

2016
Treatment of vitiligo with antiretroviral therapy in a child with HIV infection.
    AIDS (London, England), 2016, 05-15, Volume: 30, Issue:8

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Drug Therapy, Combination; Follow-Up Studies; HIV-1; Humans; Lamivudine; Male; Nevirapine; Treatment Outcome; Vitiligo; Zidovudine

2016
Zidovudine, abacavir and lamivudine increase the radiosensitivity of human esophageal squamous cancer cell lines.
    Oncology reports, 2016, Volume: 36, Issue:1

    Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Dideoxynucleosides; DNA Damage; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Lamivudine; Radiation Tolerance; Radiation-Sensitizing Agents; Telomerase; Telomere; Zidovudine

2016
Theoretical and experimental studies of the stability of drug-drug interact.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, Nov-05, Volume: 168

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Interactions; Drug Stability; Hydrogen Bonding; Lamivudine; Molecular Docking Simulation; Molecular Dynamics Simulation; Thermodynamics; Zidovudine

2016
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia.
    Antiviral therapy, 2017, Volume: 22, Issue:2

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Coinfection; Cyclopropanes; DNA, Viral; Drug Resistance, Viral; Ethiopia; Female; Genetic Variation; Genome, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Immune Evasion; Lamivudine; Male; Mutation; Stavudine; Viral Load; Zidovudine

2017
Treatment Outcomes and Resistance Patterns of Children and Adolescents on Second-Line Antiretroviral Therapy in Asia.
    Journal of acquired immune deficiency syndromes (1999), 2016, 08-01, Volume: 72, Issue:4

    Topics: Adolescent; Anti-HIV Agents; CD4 Lymphocyte Count; Child; Child, Preschool; Dideoxynucleosides; Drug Resistance, Multiple, Viral; Female; HIV Infections; HIV-1; Humans; Indonesia; Lamivudine; Male; Prospective Studies; Ritonavir; Thailand; Treatment Outcome; Vietnam; Viral Load; Zidovudine

2016
Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:7

    Topics: Animals; Anti-HIV Agents; Bone Marrow Cells; Brain; Dideoxynucleosides; DNA, Mitochondrial; Drug Therapy, Combination; Erythrocebus patas; Female; Gestational Age; Heart; Lamivudine; Mitochondria; Mitochondria, Heart; Oxygen Consumption; Pregnancy; Prenatal Exposure Delayed Effects; Zidovudine

2016
Improved Adherence to Antiretroviral Therapy Observed Among HIV-Infected Children Whose Caregivers had Positive Beliefs in Medicine in Sub-Saharan Africa.
    AIDS and behavior, 2017, Volume: 21, Issue:2

    Topics: Africa South of the Sahara; Alkynes; Anti-HIV Agents; Attitude to Health; Benzoxazines; Caregivers; Child; Child, Preschool; Cyclopropanes; Dideoxynucleosides; Female; HIV Infections; Humans; Infant; Lamivudine; Linear Models; Logistic Models; Male; Medication Adherence; Multivariate Analysis; Nevirapine; Randomized Controlled Trials as Topic; Stavudine; Surveys and Questionnaires; Uganda; Zambia; Zidovudine

2017
Genotoxic and Cytotoxic Effects of Antiretroviral Combinations in Mice Bone Marrow.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Animals; Antiretroviral Therapy, Highly Active; Bone Marrow; Comet Assay; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Lamivudine; Mice; Micronuclei, Chromosome-Defective; Tenofovir; Zidovudine

2016
Survival Outcomes in a Pediatric Antiretroviral Treatment Cohort in Southern Malawi.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adolescent; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Child; Child, Preschool; Cohort Studies; Cyclopropanes; Dideoxynucleotides; Female; HIV Infections; HIV Wasting Syndrome; Humans; Infant; Lamivudine; Malawi; Male; Proportional Hazards Models; Retrospective Studies; Rural Population; Stavudine; Survival Analysis; Tuberculosis, Pulmonary; Zidovudine

2016
Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Animals; Anti-HIV Agents; Chlorocebus aethiops; Ebolavirus; Guinea Pigs; HeLa Cells; Hemorrhagic Fever, Ebola; Humans; Lamivudine; Macrophages; Pilot Projects; Vero Cells; Virus Replication; Zidovudine

2016
Triple Drug Combination of Zidovudine, Efavirenz and Lamivudine Loaded Lactoferrin Nanoparticles: an Effective Nano First-Line Regimen for HIV Therapy.
    Pharmaceutical research, 2017, Volume: 34, Issue:2

    Topics: Alkynes; Animals; Anti-Retroviral Agents; Benzoxazines; Cell Line, Tumor; Cyclopropanes; Drug Combinations; Female; Half-Life; HIV Infections; HIV-1; Humans; Lactoferrin; Lamivudine; Male; Nanoparticles; Rats; Rats, Wistar; Tissue Distribution; Zidovudine

2017
Early antiretroviral treatment (eART) limits viral diversity over time in a long-term HIV viral suppressed perinatally infected child.
    BMC infectious diseases, 2016, Dec-09, Volume: 16, Issue:1

    Topics: Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Lamivudine; Lopinavir; Male; Nevirapine; Phylogeny; Ritonavir; Zidovudine

2016
Antiretrovirals causing severe pre-eclampsia.
    Pregnancy hypertension, 2016, Volume: 6, Issue:4

    Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Delivery, Obstetric; Female; HIV Infections; Humans; Infant, Extremely Low Birth Weight; Infant, Newborn; Lamivudine; Nevirapine; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Infectious; Tenofovir; Zidovudine

2016
Safety of zidovudine/lamivudine scored tablets in children with HIV infection in Europe and Thailand.
    European journal of clinical pharmacology, 2017, Volume: 73, Issue:4

    Topics: Anti-HIV Agents; Child; Europe; HIV Infections; Humans; Lamivudine; Tablets; Thailand; Zidovudine

2017
Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa.
    The Journal of antimicrobial chemotherapy, 2017, 05-01, Volume: 72, Issue:5

    Topics: Adult; Africa South of the Sahara; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Polymerase Chain Reaction; Retrospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Thymidine; Treatment Failure; Viral Load; Zidovudine

2017
Triple-drug antiretroviral therapy results in lower HIV maternal-fetal transmission rates but increased adverse effects compared with zidovudine alone.
    The Journal of pediatrics, 2017, Volume: 182

    Topics: Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy Complications, Infectious; Zidovudine

2017
Modelling CD4 T Cell Recovery in Hepatitis C and HIV Co-infected Children Receiving Antiretroviral Therapy.
    The Pediatric infectious disease journal, 2017, Volume: 36, Issue:5

    Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Cohort Studies; Coinfection; Drug Combinations; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Interferon-alpha; Lamivudine; Lopinavir; Male; Models, Immunological; Polyethylene Glycols; Recombinant Proteins; Recovery of Function; Ribavirin; Ritonavir; Time-to-Treatment; Zidovudine

2017
Factors associated with loss to follow-up after occupational HIV exposure in Cape Town, South Africa: a retrospective cohort study.
    AIDS research and therapy, 2017, Apr-21, Volume: 14, Issue:1

    Topics: Adult; Anti-HIV Agents; Emtricitabine; Female; Health Personnel; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Lost to Follow-Up; Male; Occupational Exposure; Post-Exposure Prophylaxis; Retrospective Studies; South Africa; Stavudine; Tenofovir; Young Adult; Zidovudine

2017
On assessing bioequivalence and interchangeability between generics based on indirect comparisons.
    Statistics in medicine, 2017, Aug-30, Volume: 36, Issue:19

    Topics: Anti-HIV Agents; Antimalarials; Artemether; Artemisinins; Computer Simulation; Confidence Intervals; Drugs, Generic; Ethanolamines; Fluorenes; HIV Infections; Humans; Lamivudine; Lumefantrine; Malaria; Models, Statistical; Therapeutic Equivalency; Zidovudine

2017
Multi-state models for the analysis of time-to-treatment modification among HIV patients under highly active antiretroviral therapy in Southwest Ethiopia.
    BMC infectious diseases, 2017, 06-27, Volume: 17, Issue:1

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Therapy, Combination; Ethiopia; Female; HIV Infections; Humans; Lamivudine; Male; Models, Theoretical; Nevirapine; Pregnancy; Retrospective Studies; Stavudine; Tenofovir; Time-to-Treatment; Treatment Failure; Zidovudine

2017
Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Resistance, Viral; Genotype; Heterocyclic Compounds, 3-Ring; HIV-1; Lamivudine; Lopinavir; Nelfinavir; Oxazines; Piperazines; Pyridones; Reverse Transcriptase Inhibitors; Ritonavir; Zidovudine

2017
Efficacy and safety of switching from branded to generic antiretrovirals in virologically suppressed HIV-infected patients.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cohort Studies; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Drug Therapy, Combination; Drugs, Generic; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Patient Safety; Poisson Distribution; RNA, Viral; Treatment Outcome; Zidovudine

2017
Accumulation of HIV-1 drug resistance in patients on a standard thymidine analogue-based first line antiretroviral therapy after virological failure: implications for the activity of next-line regimens from a longitudinal study in Mozambique.
    BMC infectious diseases, 2017, 09-05, Volume: 17, Issue:1

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Longitudinal Studies; Male; Mozambique; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2017
Susceptibility of Human Endogenous Retrovirus Type K to Reverse Transcriptase Inhibitors.
    Journal of virology, 2017, 12-01, Volume: 91, Issue:23

    Topics: Anti-HIV Agents; Cell Line, Tumor; Endogenous Retroviruses; Genome, Viral; Humans; Integrase Inhibitors; Lamivudine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Reverse Transcription; Stavudine; Virus Replication; Zidovudine

2017
Bullseye Retinopathy from Antiretroviral Therapy.
    Ophthalmology, 2017, Volume: 124, Issue:10

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Humans; Lamivudine; Male; Middle Aged; Retinal Diseases; Reverse Transcriptase Inhibitors; Zidovudine

2017
Concomitant AIDS cholangiopathy and Fanconi syndrome as complications of HIV in a single patient.
    BMJ case reports, 2017, Nov-21, Volume: 2017

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cholangitis; Fanconi Syndrome; Female; HIV Infections; Humans; Lamivudine; Middle Aged; Tenofovir; Zidovudine

2017
Motives for change of first-line antiretroviral therapy regimens in an unselected cohort of HIV/AIDS patients at a major referral centre in South-west Cameroon.
    BMC research notes, 2017, Nov-28, Volume: 10, Issue:1

    Topics: Adult; Anti-HIV Agents; Cameroon; Cohort Studies; Cross-Sectional Studies; Drug Combinations; Drug Substitution; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Referral and Consultation; Stavudine; Zidovudine

2017
Different Degrees of Immune Recovery Using Antiretroviral Regimens with Vonavir or Zidovudine/Lamivudine/Efavirenz in HIVPositive Patients Receiving First Line Treatment in Iran.
    Infectious disorders drug targets, 2018, Volume: 18, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cohort Studies; Cyclopropanes; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Immunity, Cellular; Iran; Lamivudine; Male; Retrospective Studies; Reverse Transcriptase Inhibitors; Sex Factors; Time Factors; Zidovudine

2018
Simultaneous quantification of four antiretroviral drugs in breast milk samples from HIV-positive women by an ultra-high performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method.
    PloS one, 2018, Volume: 13, Issue:1

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Breast Feeding; Calibration; Chromatography, High Pressure Liquid; Colostrum; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Milk, Human; Pregnancy; Pregnancy Complications, Infectious; Reference Standards; Reproducibility of Results; Ritonavir; Tandem Mass Spectrometry; Young Adult; Zidovudine

2018
A prospective study of adverse events to antiretroviral therapy in HIV- infected adults in Ekiti State, Nigeria.
    African journal of medicine and medical sciences, 2016, Volume: 45, Issue:2

    Topics: Abdominal Pain; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Substitution; Drug Therapy, Combination; Female; HIV Infections; Humans; Incidence; Lamivudine; Male; Middle Aged; Nausea; Nevirapine; Nigeria; Prospective Studies; Sleep Initiation and Maintenance Disorders; Tenofovir; Young Adult; Zidovudine

2016
Antiretroviral treatment Long-Term (ALT) cohort: a prospective cohort of 10 years of ART-experienced patients in Uganda.
    BMJ open, 2018, 02-21, Volume: 8, Issue:2

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nevirapine; Prospective Studies; RNA, Viral; Time; Uganda; Viral Load; Zidovudine

2018
Comparison of adherence to generic multi-tablet regimens vs. brand multi-tablet and brand single-tablet regimens likely to incorporate generic antiretroviral drugs by breaking or not fixed-dose combinations in HIV-infected patients.
    Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:4

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Drugs, Generic; Female; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Tablets; Viral Load; Zidovudine

2018
Could antiretrovirals be treating EBV in MS? A case report.
    Multiple sclerosis and related disorders, 2018, Volume: 22

    Topics: Adult; Brain; Drug Combinations; Epstein-Barr Virus Infections; Fatigue; Female; Humans; Immunologic Factors; Lamivudine; Multiple Sclerosis, Relapsing-Remitting; Reverse Transcriptase Inhibitors; Zidovudine

2018
One-by-one imprinting in two eccentric layers of hollow core-shells: Sequential electroanalysis of anti-HIV drugs.
    Biosensors & bioelectronics, 2018, Jul-15, Volume: 111

    Topics: Anti-HIV Agents; Biosensing Techniques; Electrochemical Techniques; Graphite; Humans; Lamivudine; Limit of Detection; Molecular Imprinting; Polymers; Zidovudine

2018
Birth Outcomes for Pregnant Women with HIV Using Tenofovir-Emtricitabine.
    The New England journal of medicine, 2018, 04-26, Volume: 378, Issue:17

    Topics: Adult; Anti-HIV Agents; Cohort Studies; Disease Transmission, Infectious; Drug Administration Schedule; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; Humans; Infant, Low Birth Weight; Infant, Newborn; Lamivudine; Lopinavir; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Premature Birth; Risk; Ritonavir; Tenofovir; Zidovudine

2018
Short Communication: Reduced Nevirapine Concentrations Among HIV-Positive Women Receiving Mefloquine for Intermittent Preventive Treatment for Malaria Control During Pregnancy.
    AIDS research and human retroviruses, 2018, Volume: 34, Issue:11

    Topics: Adult; Anti-HIV Agents; Antimalarials; Cross-Sectional Studies; Drug Interactions; Female; Fetal Blood; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Kenya; Lamivudine; Malaria; Mefloquine; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Zidovudine

2018
Assessment of complex genomic alterations induced by AZT, 3TC, and the combination AZT +3TC.
    Drug and chemical toxicology, 2020, Volume: 43, Issue:4

    Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CHO Cells; Cricetulus; DNA Damage; Lamivudine; Mutagenesis; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

2020
Patterns of adverse drug reaction signals in NAFDAC pharmacovigilance activities from January to June 2015: safety of drug use in Nigeria.
    Pharmacology research & perspectives, 2018, Volume: 6, Issue:5

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Anti-HIV Agents; Child; Child, Preschool; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Lamivudine; Male; Middle Aged; Nevirapine; Nigeria; Pharmacovigilance; Sex Factors; Young Adult; Zidovudine

2018
Zidovudine-Mediated Autophagy Inhibition Enhances Mitochondrial Toxicity in Muscle Cells.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:1

    Topics: Anti-HIV Agents; Autophagy; Cell Line; Cell Survival; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mitochondria; Muscle Cells; Reactive Oxygen Species; Reverse Transcriptase Inhibitors; Zidovudine

2019
Toxicity and genotoxicity induced by abacavir antiretroviral medication alone or in combination with zidovudine and/or lamivudine in Drosophila melanogaster.
    Human & experimental toxicology, 2019, Volume: 38, Issue:4

    Topics: Animals; Anti-HIV Agents; Dideoxynucleosides; DNA Damage; Drosophila melanogaster; Drug Synergism; Lamivudine; Mutation; Recombination, Genetic; Zidovudine

2019
Adherence, virological outcome, and drug resistance in Chinese HIV patients receiving first-line antiretroviral therapy from 2011 to 2015.
    Medicine, 2018, Volume: 97, Issue:50

    Topics: Adult; Anti-HIV Agents; China; Drug Resistance, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Medication Adherence; Middle Aged; Retrospective Studies; Stavudine; Sustained Virologic Response; Tenofovir; Zidovudine

2018
Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome
    The New England journal of medicine, 2018, 12-06, Volume: 379, Issue:23

    Topics: Autoimmune Diseases of the Nervous System; Cerebrovascular Circulation; Dideoxynucleosides; Drug Combinations; France; Gene Expression; Humans; Interferons; Lamivudine; Nervous System Malformations; Pilot Projects; Reverse Transcriptase Inhibitors; Zidovudine

2018
Antiretroviral Drug Concentrations in Breastmilk, Maternal HIV Viral Load, and HIV Transmission to the Infant: Results From the BAN Study.
    Journal of acquired immune deficiency syndromes (1999), 2019, 04-01, Volume: 80, Issue:4

    Topics: Adolescent; Adult; Anti-HIV Agents; Breast Feeding; Female; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Middle Aged; Milk, Human; Pregnancy; Ritonavir; RNA, Viral; Viral Load; Young Adult; Zidovudine

2019
Rates of HBV, HCV, HDV and HIV type 1 among pregnant women and HIV type 1 drug resistance-associated mutations in breastfeeding women on antiretroviral therapy.
    BMC pregnancy and childbirth, 2018, Dec-22, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Breast Feeding; Cameroon; Coinfection; Drug Resistance, Viral; Female; Health Knowledge, Attitudes, Practice; Hepatitis B; Hepatitis B Antibodies; Hepatitis B Vaccines; Hepatitis C; Hepatitis C Antibodies; Hepatitis D; HIV Seroprevalence; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mutation; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Vaccination; Young Adult; Zidovudine

2018
Risk of false conformity decisions of multicomponent items controlled by correlated measurement results due to the sharing of analytical steps.
    Talanta, 2019, May-01, Volume: 196

    Topics: Chromatography, High Pressure Liquid; Decision Making; Lamivudine; Monte Carlo Method; Tablets; Uncertainty; Zidovudine

2019
Zidovudine, tenofovir or abacavir? Different adverse effect profiles.
    Prescrire international, 2016, Volume: 25, Issue:173

    Topics: Dideoxynucleosides; Drug Combinations; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2016
Rate of viral load change and adherence of HIV adult patients treated with Efavirenz or Nevirapine antiretroviral regimens at 24 and 48 weeks in Yaoundé, Cameroon: a longitudinal cohort study.
    BMC infectious diseases, 2019, Feb-26, Volume: 19, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cameroon; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nevirapine; Patient Compliance; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome; Viral Load; Zidovudine

2019
Incidence and types of HIV-1 drug resistance mutation among patients failing first-line antiretroviral therapy.
    Journal of pharmacological sciences, 2019, Volume: 139, Issue:4

    Topics: Adult; Alkynes; Antiretroviral Therapy, Highly Active; Antiviral Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Incidence; Lamivudine; Male; Middle Aged; Mutation; Nevirapine; Stavudine; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2019
Neurodevelopmental effects of ante-partum and post-partum antiretroviral exposure in HIV-exposed and uninfected children versus HIV-unexposed and uninfected children in Uganda and Malawi: a prospective cohort study.
    The lancet. HIV, 2019, Volume: 6, Issue:8

    Topics: Anti-Retroviral Agents; Breast Feeding; Child, Preschool; Cohort Studies; Drug Combinations; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Malawi; Male; Post-Exposure Prophylaxis; Postpartum Period; Pre-Exposure Prophylaxis; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Ritonavir; Uganda; Zidovudine

2019
Safety of 6-week Neonatal Triple-combination Antiretroviral Postexposure Prophylaxis in High-risk HIV-exposed Infants.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:10

    Topics: Anti-Retroviral Agents; Chemoprevention; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Nevirapine; Post-Exposure Prophylaxis; Prospective Studies; Thailand; Treatment Outcome; Zidovudine

2019
Effects of Highly Active Antiretroviral Therapy on Albuminuria in HIVinfected Persons.
    Infectious disorders drug targets, 2020, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Age Factors; Albuminuria; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Drug Combinations; Drug Therapy, Combination; Female; Glomerular Filtration Rate; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Prospective Studies; Sex Factors; Tenofovir; Young Adult; Zidovudine

2020
Trend of HIV transmitted drug resistance before and after implementation of HAART regimen restriction in the treatment of HIV-1 infected patients in southern Taiwan.
    BMC infectious diseases, 2019, Aug-23, Volume: 19, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Mutation; Nevirapine; Prevalence; Reverse Transcriptase Inhibitors; Taiwan; Zidovudine

2019
Formulation, Development and Scale-Up of Fixed-Dose Combination Tablets Containing Zidovudine, Lamivudine and Nevirapine.
    Current HIV research, 2019, Volume: 17, Issue:5

    Topics: Anti-HIV Agents; Drug Combinations; Drug Compounding; Drug Development; Drug Stability; Lamivudine; Nevirapine; Tablets; Technology, Pharmaceutical; Zidovudine

2019
Zidovudine and Lamivudine as Potential Agents to Combat HIV-Associated Neurocognitive Disorder.
    Assay and drug development technologies, 2019, Volume: 17, Issue:7

    Topics: Animals; Anti-HIV Agents; Chromatography, Liquid; Female; HIV Infections; Injections, Intraperitoneal; Lamivudine; Neurocognitive Disorders; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tissue Distribution; Zidovudine

2019
HIV Drug Resistance after Failure of 6 Month First-line Therapy in a Hospital: A Case Series.
    Acta medica Indonesiana, 2019, Volume: 51, Issue:3

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Tenofovir; Treatment Failure; Viral Load; Zidovudine

2019
Association of maternal antiretroviral use with microcephaly in children who are HIV-exposed but uninfected (SMARTT): a prospective cohort study.
    The lancet. HIV, 2020, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Child; Child, Preschool; Cyclopropanes; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Microcephaly; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Puerto Rico; Tenofovir; Young Adult; Zidovudine

2020
Effects of dissolved organic matter derived from freshwater and seawater on photodegradation of three antiviral drugs.
    Environmental pollution (Barking, Essex : 1987), 2020, Volume: 258

    Topics: Acyclovir; Antiviral Agents; Fresh Water; Humic Substances; Lamivudine; Photolysis; Seawater; Water Pollutants, Chemical; Zidovudine

2020
Descriptive analysis of World Health Organization-recommended second-line antiretroviral treatment: A retrospective cohort data analysis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2019, Nov-27, Volume: 109, Issue:12

    Topics: Adult; Age Factors; CD4 Lymphocyte Count; Databases, Factual; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Lost to Follow-Up; Male; Medication Adherence; Middle Aged; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Sex Factors; Tenofovir; Treatment Failure; Viral Load; World Health Organization; Zidovudine

2019
Safety and Efficacy of Starting Antiretroviral Therapy in the First Week of Life.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 02-01, Volume: 72, Issue:3

    Topics: Anti-HIV Agents; Botswana; Child; Child, Preschool; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nevirapine; Zidovudine

2021
Cryptococcal meningitis and immune reconstitution inflammatory syndrome in a pediatric patient with HIV after switching to second line antiretroviral therapy: a case report.
    BMC infectious diseases, 2020, Jan-21, Volume: 20, Issue:1

    Topics: AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antifungal Agents; Antigens, Fungal; Benzoxazines; Child; Cryptococcus neoformans; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Female; Fluconazole; HIV; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Lopinavir; Meningitis, Cryptococcal; Ritonavir; Treatment Outcome; Viral Load; Zidovudine

2020
Incidence and predictors of loss to follow up among adult HIV patients on antiretroviral therapy in University of Gondar Comprehensive Specialized Hospital: A competing risk regression modeling.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Ambulatory Care; Anti-Retroviral Agents; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; Hospitals, Special; Humans; Incidence; Lamivudine; Lost to Follow-Up; Male; Nevirapine; Regression Analysis; Retrospective Studies; Risk Factors; Young Adult; Zidovudine

2020
The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains.
    BMC infectious diseases, 2020, Feb-11, Volume: 20, Issue:1

    Topics: Anti-HIV Agents; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Mutation Rate; Polymorphism, Genetic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Failure; Virus Replication; Zidovudine

2020
Antiretroviral Prophylaxis: A Digestive Complication to Know.
    Pediatric emergency care, 2021, Dec-01, Volume: 37, Issue:12

    Topics: Anti-HIV Agents; Child; Drug-Related Side Effects and Adverse Reactions; HIV Infections; Humans; Lamivudine; Zidovudine

2021
Influence of a herbal preparation on the pharmacokinetics of highly active antiretroviral therapy drugs in rats.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:1

    Topics: Alkynes; Animals; Benzoxazines; Cyclopropanes; Herb-Drug Interactions; Lamivudine; Male; Rats; Zidovudine

2020
Simple thin layer chromatography-ultraviolet spectrophotometric method for quality assessment of binary fixed-dose-combinations of lamivudine/tenofovir disoproxil fumarate and lamivudine/zidovudine in tablet formulations.
    Journal of separation science, 2020, Volume: 43, Issue:11

    Topics: Anti-HIV Agents; Chromatography, Thin Layer; Drug Combinations; Drug Compounding; Lamivudine; Molecular Structure; Spectrophotometry, Ultraviolet; Tablets; Tenofovir; Zidovudine

2020
Perinatal Antiretroviral Intensification to Prevent Intrapartum HIV Transmission When Antenatal Antiretroviral Therapy Is Initiated Less Than 8 Weeks Before Delivery.
    Journal of acquired immune deficiency syndromes (1999), 2020, 07-01, Volume: 84, Issue:3

    Topics: Adult; Anti-HIV Agents; Bayes Theorem; Drug Combinations; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Mothers; Nevirapine; Pregnancy; Pregnancy Complications, Infectious; Thailand; Viral Load; Young Adult; Zidovudine

2020
Movement disorder in a patient with Human Immunodeficiency Virus on an anti-retroviral therapy: A Case Report.
    JPMA. The Journal of the Pakistan Medical Association, 2020, Volume: 70, Issue:4

    Topics: AIDS Dementia Complex; Alkynes; Anti-HIV Agents; Benzoxazines; Blood-Brain Barrier; Brain Stem; Cerebellar Ataxia; Cerebellum; Cyclopropanes; Drug Substitution; Female; Gait Ataxia; HIV Infections; Humans; Lamivudine; Magnetic Resonance Imaging; Mesencephalon; Middle Aged; Neurodegenerative Diseases; Nystagmus, Pathologic; Panic Disorder; Pons; Postural Balance; Sensation Disorders; Tenofovir; Zidovudine

2020
Assessment of lamivudine, zidovudine, lopinavir, and ritonavir plasma levels in HIV-positive pregnant women: Drug monitoring application to improve patient safety.
    Medicine, 2020, May-29, Volume: 99, Issue:22

    Topics: Adult; Anti-HIV Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Female; HIV Seropositivity; Humans; Lamivudine; Lopinavir; Patient Safety; Pregnancy; Ritonavir; Tandem Mass Spectrometry; Viral Load; Zidovudine

2020
Zidovudine and lamivudine reach higher concentrations in ventricular than in lumbar human cerebrospinal fluid.
    AIDS (London, England), 2020, 11-01, Volume: 34, Issue:13

    Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; RNA, Viral; Spinal Puncture; Stavudine; Viral Load; Zidovudine

2020
Importance of early identification of PrEP breakthrough infections in a generalized HIV epidemic: a case report from a PrEP demonstration project in South Africa.
    BMC infectious diseases, 2020, Jul-22, Volume: 20, Issue:1

    Topics: Administration, Oral; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Combinations; Drug Resistance, Viral; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Epidemics; Female; HIV Seropositivity; HIV-1; Humans; Lamivudine; Pre-Exposure Prophylaxis; Retrospective Studies; South Africa; Treatment Outcome; Viral Load; Young Adult; Zidovudine

2020
Case report: one case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a normal CD4
    AIDS research and therapy, 2020, 07-23, Volume: 17, Issue:1

    Topics: Alkynes; Anti-Retroviral Agents; Benzoxazines; Betacoronavirus; C-Reactive Protein; CD4 Lymphocyte Count; Chills; Coronavirus Infections; COVID-19; Cyclopropanes; Fatigue; Female; Fever; HIV; HIV Infections; Humans; Immunocompromised Host; Immunoglobulin M; Lamivudine; Middle Aged; Pandemics; Pharyngitis; Pneumonia, Viral; Real-Time Polymerase Chain Reaction; SARS-CoV-2; Sputum; Time Factors; Tomography, X-Ray Computed; Virus Shedding; Zidovudine

2020
Effect of combination antiretroviral therapy on human immunodeficiency virus 1 specific antibody responses in subtype-C infected children.
    The Journal of general virology, 2020, Volume: 101, Issue:12

    Topics: Anti-HIV Agents; Antibodies, Neutralizing; Antibody-Dependent Cell Cytotoxicity; Antiretroviral Therapy, Highly Active; Child, Preschool; Cohort Studies; Dideoxynucleosides; Drug Combinations; HIV Antibodies; HIV Infections; HIV-1; Humans; Infant; Lamivudine; Lopinavir; Ritonavir; Viral Load; Zidovudine

2020
Risk factors for delayed viral suppression on first-line antiretroviral therapy among persons living with HIV in Haiti, 2013-2017.
    PloS one, 2020, Volume: 15, Issue:10

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Female; Haiti; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nevirapine; Risk Factors; Viral Load; Young Adult; Zidovudine

2020
Prevalence and evaluation of risk factors of anti-retroviral therapy failure among human immunodeficiency virus/acquired immune deficiency syndrome patients in North India.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2021, 09-03, Volume: 115, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; HIV; HIV Infections; Humans; India; Lamivudine; Male; Prevalence; Risk Factors; Viral Load; Zidovudine

2021
In utero and peripartum antiretroviral exposure as predictor of cognition in 6- to 10-year-old HIV-exposed Ugandan children - a prospective cohort study.
    HIV medicine, 2021, Volume: 22, Issue:7

    Topics: Anti-HIV Agents; Child; Cognition; Female; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Uganda; Zidovudine

2021
A Combination of Amino Acid Mutations Leads to Resistance to Multiple Nucleoside Analogs in Reverse Transcriptases from HIV-1 Subtypes B and C.
    Antimicrobial agents and chemotherapy, 2022, 01-18, Volume: 66, Issue:1

    Topics: Amino Acids; Anti-HIV Agents; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Zidovudine

2022
Nevirapine hair and plasma concentrations and HIV-1 viral suppression among HIV infected ante-partum and post-partum women attended in a mother and child prevention program in Maputo city, Mozambique.
    PloS one, 2022, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Drug Combinations; Female; Hair; HIV Infections; HIV-1; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Logistic Models; Medication Adherence; Mozambique; Nevirapine; Postpartum Period; Pregnancy; Prospective Studies; Viral Load; Young Adult; Zidovudine

2022
Developmental Disorder Probability Scores at 6-18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children.
    International journal of environmental research and public health, 2022, 03-21, Volume: 19, Issue:6

    Topics: Adolescent; Anti-HIV Agents; Anti-Retroviral Agents; Autism Spectrum Disorder; Child; Developmental Disabilities; Female; HIV Infections; Humans; Lamivudine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Probability; Uganda; Zidovudine

2022
Patterns and prognosis of holding regimens for people living with HIV in Asian countries.
    PloS one, 2022, Volume: 17, Issue:3

    Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Prognosis; Reverse Transcriptase Inhibitors; Viral Load; Zidovudine

2022
Risk factors of severe hepatotoxicity among HIV-1 infected individuals initiated on highly active antiretroviral therapy in the Northwest Region of Cameroon.
    BMC gastroenterology, 2022, Jun-03, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cameroon; Chemical and Drug Induced Liver Injury; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Risk Factors; Young Adult; Zidovudine

2022
Selective modulation of placental and fetal MDR transporters by chronic in utero exposure to NRTIs in Sprague-Dawley rats: Importance for fetoprotection.
    Toxicology and applied pharmacology, 2022, 09-01, Volume: 450

    Topics: Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Resistance, Multiple; Female; Fetus; Lamivudine; Neoplasm Proteins; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Zidovudine

2022
Minimal Cross-resistance to Tenofovir in Children and Adolescents Failing ART Makes Them Eligible for Tenofovir-Lamivudine-Dolutegravir Treatment.
    The Pediatric infectious disease journal, 2022, 10-01, Volume: 41, Issue:10

    Topics: Adolescent; Anti-HIV Agents; Child; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Lamivudine; Oxazines; Piperazines; Protease Inhibitors; Pyridones; Retrospective Studies; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2022
Serum Interleukin-6 and Weight Loss in Antiretroviral-naïve and Antiretroviral-treated Patients with HIV/AIDS: Relationships and Predictors.
    Current HIV research, 2022, Volume: 20, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Emtricitabine; HIV Infections; Humans; Interleukin-6; Lamivudine; Middle Aged; Nevirapine; Tenofovir; Weight Loss; Zidovudine

2022
Rate of virological failure and HIV-1 drug resistance among HIV-infected adolescents in routine follow-up on health facilities in Cameroon.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Adolescent; Anti-HIV Agents; Cameroon; Drug Resistance, Viral; Follow-Up Studies; Health Facilities; HIV Infections; HIV Seropositivity; HIV-1; Humans; Lamivudine; Nevirapine; Retrospective Studies; Viral Load; Zidovudine

2022
Rapid simultaneous analysis of anti human immunodeficiency virus drugs in pharmaceutical formulation by smart spectrophotometry based on multivariate calibration and least squares support vector machine methods.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2023, Apr-05, Volume: 290

    Topics: Calibration; Drug Compounding; HIV; Lamivudine; Least-Squares Analysis; Spectrophotometry; Support Vector Machine; Zidovudine

2023
Growth differences by school-age and adolescence according to in utero and peripartum antiretroviral therapy exposure among Ugandan children.
    Medicine, 2023, Jan-27, Volume: 102, Issue:4

    Topics: Adolescent; Anti-HIV Agents; Anti-Retroviral Agents; Child; Cohort Studies; Female; HIV Infections; Humans; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Peripartum Period; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Uganda; Zidovudine

2023
Short-term toxicity assessment of combined use of zidovudine, lamivudine and lopinavir/ritonavir in vitro and in vivo.
    Basic & clinical pharmacology & toxicology, 2023, Volume: 133, Issue:1

    Topics: Animals; Anti-HIV Agents; Female; HIV Infections; Infectious Disease Transmission, Vertical; Lamivudine; Lopinavir; Male; Mammals; Mice; Rats; Ritonavir; Zidovudine

2023
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket.
    European journal of medicinal chemistry, 2016, Jun-10, Volume: 115

    Topics: Anti-HIV Agents; Binding Sites; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Virus Replication

2016
1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus.
    Bioorganic & medicinal chemistry, 2016, 06-01, Volume: 24, Issue:11

    Topics: Animals; Antiviral Agents; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; HIV-1; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Uracil

2016
Exploiting the hydrophobic channel of the NNIBP: Discovery of novel diarylpyrimidines as HIV-1 NNRTIs against wild-type and K103N mutant viruses.
    Bioorganic & medicinal chemistry, 2021, 07-15, Volume: 42

    Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Discovery; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Mutation; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2021