lamivudine has been researched along with saquinavir in 120 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 70 (58.33) | 18.2507 |
2000's | 38 (31.67) | 29.6817 |
2010's | 11 (9.17) | 24.3611 |
2020's | 1 (0.83) | 2.80 |
Authors | Studies |
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Bethell, RC; Cammack, N; Charon, D; Dodic, N; Dumaitre, B; Evans, DN; Green, DV; Hopewell, PL; Humber, DC; Wyatt, PG | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Hamburger, M; Hamy, F; Klimkait, T; Louvel, S; Mojarrab, M; Potterat, O; Sanglier, JJ; Vidal, V | 1 |
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
Nelson, H | 1 |
Barry, DW; Pennington, KN; Rooney, J; St Clair, MH | 1 |
Borkow, G; Castriota, G; Drosopoulos, WC; Gu, Z; Hsu, M; Islam, S; Manne, J; Parniak, M; Prasad, VR; Salomon, H; Song, Q; Wainberg, MA | 1 |
Back, D; Barry, M; Gibbons, S; Merry, C; Mulcahy, F | 1 |
Hirschel, B; Rutschmann, O | 1 |
Heins, JR | 1 |
Craib, K; Gataric, N; Hogg, RS; Montaner, JS; O'Shaughnessy, MV; Schechter, MT; Yip, B | 1 |
Costello, CE; Nelson, MR; Walsh, JC | 1 |
Heylen, R; Miller, R | 1 |
Jacobson, MA; O'Donnell, JJ; Owens, S; Pavan, PR; Pollard, R; Rao, N; Sattler, F; Zegans, M | 1 |
Fantini, J; Lafeuillade, A; Poggi, C; Tamalet, C; Yahi, N | 1 |
Mueller, BU | 1 |
Collins, DO; Sakamoto, A | 1 |
Escribano Hernández, A | 1 |
Feingold, A; Meislich, D; Rudy, B; Rutstein, RM; Word, B | 1 |
Böhlen, L; Braathen, LR; Furrer, H; Hurni, MA | 1 |
Feregrino-Goyos, M; Ortega-Larrocea, G | 1 |
Goldstein, H; Katopodis, NF; Kim, A; Kollmann, TR; Pettoello-Mantovani, M; Raker, C; Wiltshire, H; Yurasov, S | 1 |
Back, DJ; Barry, MG; Hoggard, PG; Manion, V | 1 |
Ortega-Larrocea, G; Rutzen, AR; Tanguilig, GG | 1 |
Blanchard, G; Blum, L; Calvo, F; Danne, O; Lebbé, C; Morel, P; Pellet, C; Vérola, O | 1 |
Kaiser, R; Rockstroh, JK; Sauerbruch, T; Spengler, U; Theisen, A | 1 |
Bachmeyer, C; Blum, L | 1 |
Beveridge, A; Carr, A; Cooper, DA; Cunningham, P; Duncombe, C; French, M; Kaufmann, GR; Sayer, D | 1 |
Saag, MS; Schooley, RT | 1 |
Gitterman, SR; Pratt, RD; Struble, KA | 1 |
Mayers, DL | 1 |
Brew, BJ; Markus, R | 1 |
Beckmann, A; Berger, A; Borchard, C; Dötterer, H; Eppner, MT; Esser, S; Exner, V; Fiedler, M; Goos, M; Hengge, UR; Müller, K; Wiehler, H | 1 |
Dickinson, BP; Flanigan, T; Mega, A; Mileno, MD; Mylonakis, E; Rich, JD; Schiffman, FJ | 1 |
Bruisten, SM; de Wolf, F; Frissen, PH; Jurriaans, S; Lange, JM; Mulder, JW; Reijers, MH; Schuitemaker, H; ten Kate, RW; van Leeuwen, R; Weigel, HM; Weverling, GJ; Wit, FW | 1 |
Borleffs, JC; Boucher, CA; Cohen Stuart, JW; Hamman, D; Miedema, F; Roos, M | 1 |
Lawrence, J; Merigan, TC; Schapiro, JM; Winters, MA | 1 |
Delfraissy, JF; Goujard, C; Guillet, JG; Lantz, O; Lefebvre, P; Martinon, F; Michelet, C; Peguillet, I; Taoufik, Y | 1 |
Del Villar, A; González-López, A; Pozo, T; Velasco, E | 1 |
Borleffs, JC; Boucher, CA; Bravenboer, B; Burger, DM; Cohen Stuart, JW; Hamann, D; Hoetelmans, RM; Juttmann, JR; Koopmans, PP; Kroon, FP; Meenhorst, PL; Richter, C; Schuurman, R; Sprenger, HG | 1 |
Cassano, P; Clumeck, N; De Wit, S; Gerard, M; Hermans, P; Kabeya, K; O'Doherty, E | 1 |
Arvieux, C; Bazin, C; Bellissant, E; Cartier, F; Chauvin, JP; Delfraissy, JF; Dohin, E; Michelet, C; Raffi, F; Renard, I; Ruffault, A; Sébille, V | 1 |
Kuznetsov, SL; Nikitin, IG; Storozhakov, GI; Strochenovskiĭ, AB | 1 |
Gill, MJ; Johns, DG | 1 |
Duro, G; García, C; Hernández-Burruezo, JJ; Martín-Rubio, A; Omar, M; Romero, MD | 1 |
Black, FT; Blaxhult, A; Gerstoft, J; Jensen-Fangel, S; Kirk, O; Larsen, L; Lundgren, JD; Obel, N; Pedersen, C | 1 |
Kikuchi, Y; Oka, S; Tachikawa, N; Yasuoka, A; Yoshizawa, S | 1 |
Temesgen, Z; Wright, AJ | 1 |
Flepp, M; Jost, J; Ledergerber, B; Opravil, M; Paris, D; Ruef, C; Weber, R; Zimmerli, S | 1 |
Borleffs, JC; Boucher, CA; de Boer, RJ; Hamann, D; Hazenberg, MD; Miedema, F; Otto, SA; Stuart, JW | 1 |
Copeland, KF; Fransen, S; Rosenthal, KL; Smaill, F; Smieja, M | 1 |
Gazzard, BG; Moyle, GJ | 1 |
Campi, G; Casorati, G; Corey, L; Demarest, JF; Kaufmann, D; Lazzarin, A; Lenge, C; Pantaleo, G; Rizzardi, GP; Soudeyns, H; Tambussi, G | 1 |
Hart, AA; Hoetelmans, RM; Lange, JM; Mulder, JW; Reijers, MH; Reiss, P; Schuitemaker, H; Ten Kate, RW; Weigel, HM; Weverling, GJ | 1 |
Bart, PA; Chapuis, A; De Boer, RJ; Fox, CH; Halkic, N; Hoover, S; Lange, JM; Lazzarin, A; Miller, V; Notermans, DW; Pantaleo, G; Perrin, L; Rizzardi, GP; Staszewski, S; Tambussi, G | 1 |
Butler, KM; Clarke, SM; Condon, S; Healy, CM; Mulcahy, F | 1 |
Allende, MC; Belloso, WH; Benetucci, JA; Cahn, PE; Davey, RT; Emery, S; Lane, HC; Lasala, MC; Law, MG; Lopardo, G; Losso, MH; Nelson, E; Salomon, H; Saracco, M | 1 |
Danner, SA; Gisolf, EH; Hoetelmans, RW; van Heeswijk, RP | 1 |
Ahmed, PS; Bedard, J; Bowlin, TL; Chambers, P; Clarke, J; Kelly, LA; Rando, RF; Taylor, DL; Tyms, AS; Wood, LJ | 1 |
Belohradsky, BH; Rolinski, B; Stojanov, S; Wintergerst, U | 1 |
Parkin, N; Resch, W; Stuelke, EL; Swanstrom, R; Watkins, T | 1 |
Barreiro, P; Gonzalez-Lahoz, J; Soriano, V | 1 |
Airoldi, M; Carosi, G; Castelli, F; Patroni, A; Quiros-Roldan, E; Signorini, S; Torti, C | 1 |
Hoetelmans, RM; Jurriaans, S; Lange, JM; Mulder, JW; Reijers, MH; Richter, C; Roos, MT; Schuitemaker, H; Sprenger, H; Ten Kate, RW; Ter Hofstede, HJ; Weigel, HM; Weverling, GJ; Wit, FW | 1 |
Bartley, PB; Boots, RJ; Hyland, VJ; Lawson, M; Potter, JM; Westacott, L; Woods, ML | 1 |
Farthing, C; Graham, E; Pilson, RS; Sension, MG; Shaffer, AG; Siemon-Hryczyk, P | 1 |
Conant, M | 1 |
Levin, J | 1 |
Baker, R | 2 |
Chang, HE | 1 |
Smart, T | 2 |
Alcorn, K | 1 |
Coppedge, B | 1 |
Gilden, D | 1 |
Bowersox, J | 1 |
Miller, G | 1 |
Gomez, E | 1 |
Danner, SA; de Boer, RJ; Goudsmit, J; Huismans, R; Jebbink, MF; Lukashov, VV | 1 |
Aaron, L; Carnot, F; Pialoux, G | 1 |
Chadapaud, S; Chouraqui, M; Delbeke, E; Hittinger, G; Lafeuillade, A; Poggi, C | 1 |
Chadapaud, S; Halfon, P; Hittinger, G; Khiri, H; Lafeuillade, A; Poggi, C | 1 |
Post, JJ | 1 |
Chantawuttinan, T; Dabtham, K; Hawkins, D; Hill, AM; Kanshana, S; Moyle, GJ; Sirichthaporn, P; Somburanasin, P; Supajatura, V; Vithayasai, V; Wattanatchariya, N | 1 |
Anunnatsiri, S; Boonyaprawit, P; Chetchotisakd, P; Mootsikapun, P; Wankun, J | 1 |
Aldamiz-Etxebarría, M; Andonegui Navarro, J | 1 |
Prescott, LM | 1 |
Livrozet, JM; Miossec, P; Touraine, JL; Wegrzyn, J | 1 |
Macher, A; Paul, SM; Thomas, D | 1 |
Katano, H; Kimura, S; Niino, H; Oka, S; Teruya, K; Yamamoto, Y; Yasuoka, A | 1 |
Azuaje, C; Domingo, P; Falco, V; Gatell, JM; Lopez, RM; Lopez-Colomes, JL; Mallolas, J; Ocaña, I; Pahissa, A; Pou, L; Ribera, E; Sambea, MA; Sánchez, P; Soriano, A | 1 |
Gochicoa Rangel, LG; Miranda Novales, MG; Palacios Saucedo, G; Solórzano Santos, F; Vázquez Rosales, G | 1 |
Gładysz, A; Knysz, B; Rzeszutko, M; Zalewska, M | 1 |
Becker, S; Bernstein, B; Calhoun, D; Cameron, DW; da Silva, B; Foit, C; Hanna, GJ; King, MS; Klein, C; Tokimoto, D | 1 |
Dratwa, M; Guillaume, MP; Mesquita, M | 1 |
Ananworanich, J; Côté, HC; Hill, A; Hirschel, B; Jupimai, T; Kerr, SJ; Laopraynak, N; Nuesch, R; Ruxrungtham, K; Saenawat, S | 1 |
Bickel, M; Bodtländer, A; Gute, P; Klauke, S; Knecht, GK; Kurowski, M; Lutz, T; Stephan, C; von Hentig, N | 1 |
Boonchawalit, S; Harada, S; Matsushita, S; Yamaguchi, A; Yoshimura, K; Yusa, K | 1 |
Garner, O; Iardino, A; Lorusso, G; Lotta, F | 1 |
13 review(s) available for lamivudine and saquinavir
Article | Year |
---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antiretroviral therapy: a guide to the most important trials.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Clinical Trials as Topic; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Viral Load; Zalcitabine; Zidovudine | 1997 |
Adverse effects and drug interactions of medications commonly used in the treatment of adult HIV positive patients: Part 2.
Topics: Adolescent; Adult; Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Ritonavir; Saquinavir | 1997 |
Antiviral chemotherapy.
Topics: Adult; Antiviral Agents; Child; HIV Infections; Humans; Indinavir; Lamivudine; Nevirapine; Protease Inhibitors; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine | 1997 |
[Antiretroviral treatment in human immunodeficiency virus infection].
Topics: Antiviral Agents; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Ritonavir; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zalcitabine; Zidovudine | 1997 |
Antiretroviral chemotherapy.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1998 |
Toxicity of antiretroviral agents.
Topics: Anti-HIV Agents; Didanosine; Health Personnel; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Occupational Exposure; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
Prevalence and incidence of resistance to zidovudine and other antiretroviral drugs.
Topics: Anti-HIV Agents; Drug Resistance, Microbial; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Prevalence; Reverse Transcriptase Inhibitors; Risk Factors; Saquinavir; Stavudine; Time Factors; Zidovudine | 1997 |
HIV-associated pityriasis rubra pilaris responsive to triple antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; HIV Protease Inhibitors; Humans; Lamivudine; Pityriasis Rubra Pilaris; Saquinavir; Zidovudine | 1999 |
Antiretrovirals.
Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine | 1999 |
Finding a role for zalcitabine in the HAART era.
Topics: Anti-HIV Agents; Drug Resistance; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Saquinavir; Zalcitabine; Zidovudine | 1998 |
Contraindicated antiretroviral drug combinations.
Topics: Anti-Retroviral Agents; Contraindications; Didanosine; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Zalcitabine | 2003 |
24 trial(s) available for lamivudine and saquinavir
Article | Year |
---|---|
Cytomegalovirus retinitis after initiation of highly active antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Saquinavir; Zidovudine | 1997 |
Treatment response and durability of a double protease inhibitor therapy with saquinavir and ritonavir in an observational cohort of HIV-1-infected individuals.
Topics: Adult; Anti-HIV Agents; CD4-CD8 Ratio; Cohort Studies; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Observation; Risk Factors; Ritonavir; Saquinavir; Treatment Failure; Viral Load; Zidovudine | 1998 |
Randomized, controlled phase II trial of subcutaneous interleukin-2 in combination with highly active antiretroviral therapy (HAART) in HIV patients.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Injections, Subcutaneous; Interleukin-2; Lamivudine; Male; Prospective Studies; Quality of Life; Reverse Transcriptase Inhibitors; Saquinavir; Viral Load; Zidovudine | 1998 |
[Amsterdam duration of antiretroviral medication (ADAM)--study: induction-suppression treatment in HIV-I infection, preliminary results].
Topics: Antiviral Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Nelfinavir; Pilot Projects; Saquinavir; Stavudine; Treatment Outcome; Viral Load | 1998 |
[Increased serum level of naive CD8+-T-cells during intensive antiretroviral therapy].
Topics: Antiviral Agents; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Lamivudine; Lymphocyte Count; Male; Saquinavir; Zidovudine | 1998 |
Clinical cross-resistance between the HIV-1 protease inhibitors saquinavir and indinavir and correlations with genotypic mutations.
Topics: CD4 Lymphocyte Count; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Mutation; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Viral Load; Zidovudine | 1999 |
Randomized trial comparing saquinavir soft gelatin capsules versus indinavir as part of triple therapy (CHEESE study).
Topics: Adult; Anti-HIV Agents; Capsules; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Gelatin; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Treatment Outcome; Zidovudine | 1999 |
Safety and efficacy of ritonavir and saquinavir in combination with zidovudine and lamivudine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Female; Genotype; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Mutation; Pilot Projects; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Severity of Illness Index; Time Factors; Viral Load; Zidovudine | 1999 |
[Combined polychemotherapy of patients with chronic hepatitis C].
Topics: Adolescent; Adult; Antibodies, Viral; Antiviral Agents; Chronic Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis C, Chronic; HIV Protease Inhibitors; Humans; Interferon-alpha; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Saquinavir | 1999 |
Saquinavir therapy in patients with the advanced HIV infection and liver cirrhosis.
Topics: Adult; Drug Therapy, Combination; Hemophilia A; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Liver Cirrhosis; Ritonavir; Saquinavir; Stavudine | 1999 |
T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART).
Topics: Anti-HIV Agents; Antigens, CD; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Therapy, Combination; HIV Infections; HIV Seronegativity; HIV-1; Humans; Indinavir; Ki-67 Antigen; Lamivudine; Longitudinal Studies; Lymphocyte Activation; RNA, Viral; Saquinavir; T-Lymphocyte Subsets; T-Lymphocytes; Viral Load; Zidovudine | 2000 |
RANTES production by T cells and CD8-mediated inhibition of human immunodeficiency virus gene expression before initiation of potent antiretroviral therapy predict sustained suppression of viral replication.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Chemokine CCL5; Gene Expression; HIV Infections; HIV Long Terminal Repeat; HIV-1; Humans; Lamivudine; Predictive Value of Tests; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Single-Blind Method; T-Lymphocytes; Viral Load; Virus Replication; Zidovudine | 2000 |
Toxicity and drug exposure in a quadruple drug regimen in HIV-1 infected patients participating in the ADAM study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Diarrhea; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Liver; Male; Middle Aged; Nausea; Nelfinavir; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine | 2000 |
A randomized, controlled, phase II trial comparing escalating doses of subcutaneous interleukin-2 plus antiretrovirals versus antiretrovirals alone in human immunodeficiency virus-infected patients with CD4+ cell counts >/=350/mm3.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Didanosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; Humans; Indinavir; Injections, Subcutaneous; Interleukin-2; Lamivudine; Lymphocyte Count; Male; Nelfinavir; Nevirapine; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 2000 |
The ADAM study continued: maintenance therapy after 50 weeks of induction therapy.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Time Factors; Treatment Outcome; Viral Load | 2001 |
An open-label randomized trial to evaluate different therapeutic strategies of combination therapy in HIV-1 infection: design, rationale, and methods of the initio trial.
Topics: Adult; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Patient Selection; Randomized Controlled Trials as Topic; Research Design; Ritonavir; Sample Size; Saquinavir; Stavudine; Zidovudine | 2001 |
Challenges of antiretroviral treatment in transient and drug-using populations: the SUN study.
Topics: Adult; Antiretroviral Therapy, Highly Active; Capsules; CD4 Lymphocyte Count; Chemistry, Pharmaceutical; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Mental Disorders; Patient Compliance; Pilot Projects; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Saquinavir; Substance Abuse, Intravenous; Transients and Migrants; Treatment Outcome; Viral Load; Zidovudine | 2001 |
HIV-1 induction-maintenance at the lymph node level: the "Apollo-97" Study.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biopsy; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; France; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lymph Nodes; Lymphocyte Subsets; Lymphocytes; Male; Polymerase Chain Reaction; Ritonavir; RNA, Viral; Saquinavir; Time Factors; Viral Load; Viremia; Virus Replication | 2001 |
Potential adverse effects of structured therapeutic interruptions on the pool of HIV-infected cells.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Didanosine; Disease Progression; HIV Infections; HIV-1; Humans; Lamivudine; Lymphocyte Count; Morbidity; Prognosis; Ritonavir; RNA, Viral; Saquinavir; Viral Load; Zidovudine | 2001 |
Safety and efficacy of saquinavir soft-gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission.
Topics: Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Safety; Saquinavir; Thailand; United Kingdom; Viremia; Zidovudine | 2002 |
A randomized, open-label, comparative trial of BID and TID dosing of saquinavir enhanced oral formulation as part of a triple therapy for advanced AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Female; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Zidovudine | 2002 |
Once-daily regimen of saquinavir, ritonavir, didanosine, and lamivudine in HIV-infected patients with standard tuberculosis therapy (TBQD Study).
Topics: Adult; Anti-HIV Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Pilot Projects; Ritonavir; Saquinavir; Spain; Treatment Outcome; Tuberculosis | 2005 |
Exploratory study comparing the metabolic toxicities of a lopinavir/ritonavir plus saquinavir dual protease inhibitor regimen versus a lopinavir/ritonavir plus zidovudine/lamivudine nucleoside regimen.
Topics: Adult; Anti-HIV Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Lopinavir; Male; Middle Aged; Pyrimidinones; Ritonavir; Saquinavir; Zidovudine | 2007 |
Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy.
Topics: Absorptiometry, Photon; Adenine; Adult; Anti-HIV Agents; Body Fat Distribution; Didanosine; DNA, Mitochondrial; HIV Infections; Humans; Lamivudine; Lipids; Liver Function Tests; Organophosphonates; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Tenofovir; Thailand | 2008 |
83 other study(ies) available for lamivudine and saquinavir
Article | Year |
---|---|
Benzophenone derivatives: a novel series of potent and selective inhibitors of human immunodeficiency virus type 1 reverse transcriptase.
Topics: Benzophenones; Cell Line; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 1995 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Library-based discovery and characterization of daphnane diterpenes as potent and selective HIV inhibitors in Daphne gnidium.
Topics: Anti-HIV Agents; CCR5 Receptor Antagonists; Daphne; Diterpenes; Heterocyclic Compounds, 4 or More Rings; Mediterranean Region; Molecular Structure; Receptors, CXCR4 | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
FDA advised to license three anti-HIV agents.
Topics: Adult; Antiviral Agents; Child; Drug Approval; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine | 1995 |
In vitro comparison of selected triple-drug combinations for suppression of HIV-1 replication: the Inter-Company Collaboration Protocol.
Topics: Antiviral Agents; Cell Line, Transformed; Cytopathogenic Effect, Viral; Didanosine; Drug Synergism; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nevirapine; Pyridines; Quinolines; Reverse Transcriptase Inhibitors; Saquinavir; Virus Replication; Zalcitabine; Zidovudine | 1995 |
New drugs for HIV infection.
Topics: Antiviral Agents; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Zalcitabine | 1996 |
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase.
Topics: Antiviral Agents; Base Composition; Base Sequence; Deoxyribonucleotides; Drug Resistance, Microbial; HIV Antibodies; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Isoquinolines; Lamivudine; Molecular Sequence Data; Mutation; Neutralization Tests; Quinolines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Saquinavir; Virus Replication; Zalcitabine | 1996 |
[HIV: to administer protease inhibitors early].
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Time Factors; Zalcitabine; Zidovudine | 1996 |
Saquinavir interaction with midazolam: pharmacokinetic considerations when prescribing protease inhibitors for patients with HIV disease.
Topics: Adult; Anti-HIV Agents; Cytochrome P-450 Enzyme System; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Hypnotics and Sedatives; Lamivudine; Liver; Male; Midazolam; Saquinavir; Trimethoprim, Sulfamethoxazole Drug Combination; Zidovudine | 1997 |
Treatment options for human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Child; Didanosine; Drug Approval; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant, Newborn; Lamivudine; Male; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
Decline in deaths from AIDS due to new antiretrovirals.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; British Columbia; CD4 Lymphocyte Count; Drug Therapy, Combination; Humans; Indinavir; Lamivudine; Mortality; Saquinavir; Stavudine | 1997 |
Response of HIV-associated thrombocytopenia to triple agent antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Male; Saquinavir; Thrombocytopenia; Zalcitabine; Zidovudine | 1997 |
Quantification of HIV-1 viral load in lymphoid and blood cells: assessment during four-drug combination therapy.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Lymph Nodes; Male; Polymerase Chain Reaction; RNA, Viral; Saquinavir; Viral Load; Viremia; Zidovudine | 1997 |
Cure or control of HIV/AIDS?
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; Humans; Indinavir; Lamivudine; Models, Biological; Nevirapine; Pyridines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1997 |
[The management of the occupational exposures of health workers to HIV].
Topics: Anti-HIV Agents; Drug Interactions; Drug Therapy, Combination; Health Personnel; HIV Infections; HIV-1; Humans; Indinavir; Infectious Disease Transmission, Patient-to-Professional; Lamivudine; Occupational Exposure; Saquinavir; Zidovudine | 1997 |
Protease inhibitor therapy in children with perinatally acquired HIV infection.
Topics: Anti-HIV Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Male; Protease Inhibitors; Retrospective Studies; Ritonavir; Saquinavir; Stavudine; Zidovudine | 1997 |
Complete regression of giant molluscum contagiosum lesions in an HIV-infected patient following combined antiretroviral therapy with saquinavir, zidovudine and lamivudine.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Drug Therapy, Combination; Humans; Lamivudine; Male; Molluscum Contagiosum; Saquinavir; Zidovudine | 1997 |
Drugs for HIV infection.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Delavirdine; Diarrhea; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Virus Replication; Zalcitabine; Zidovudine | 1997 |
Nonprogressive CMV retinitis in AIDS patients with protease inhibitors therapy for AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Drug Therapy, Combination; Fundus Oculi; Ganciclovir; HIV Protease Inhibitors; Humans; Lamivudine; Male; Ritonavir; Saquinavir | 1997 |
thy/liv-SCID-hu mice: a system for investigating the in vivo effects of multidrug therapy on plasma viremia and human immunodeficiency virus replication in lymphoid tissues.
Topics: Animals; Anti-HIV Agents; Chronic Disease; Drug Resistance, Microbial; Drug Therapy, Combination; Fetal Tissue Transplantation; Flow Cytometry; HIV Infections; HIV-1; Lamivudine; Leukocytes, Mononuclear; Liver Transplantation; Mice; Mice, SCID; Recurrence; Ritonavir; RNA, Viral; Saquinavir; Thymus Gland; Viremia; Zidovudine | 1998 |
Effect of protease inhibitors on nucleoside analogue phosphorylation in vitro.
Topics: Anti-HIV Agents; Cell Count; Cell Survival; Didanosine; Drug Interactions; Humans; Indinavir; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Phosphorylation; Protease Inhibitors; Ritonavir; Saquinavir; Stavudine; Trypan Blue; Tumor Cells, Cultured; Zalcitabine; Zidovudine | 1998 |
Regression of cytomegalovirus retinitis associated with protease-inhibitor treatment in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cytomegalovirus Retinitis; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Saquinavir; Stavudine; Zidovudine | 1998 |
Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Didanosine; Dideoxynucleosides; Drug Therapy, Combination; Female; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Middle Aged; Prospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sarcoma, Kaposi; Stavudine; Treatment Outcome; Viral Load; Viremia; Zalcitabine; Zidovudine | 1998 |
Antiretroviral triple therapy decreases HIV viral load but does not alter hepatitis C virus (HCV) serum levels in HIV-HCV-co-infected haemophiliacs.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cohort Studies; Drug Therapy, Combination; Hemophilia A; Hepacivirus; Hepatitis C; HIV; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Treatment Outcome; Viral Load; Zidovudine | 1998 |
HIV-1 peripheral neuropathy and combination antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Male; Middle Aged; Nelfinavir; Nevirapine; Peripheral Nervous System Diseases; Saquinavir; Zidovudine | 1998 |
Persistent parvovirus B19 related anemia of seven years' duration in an HIV-infected patient: complete remission associated with highly active antiretroviral therapy.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Erythrocyte Transfusion; HIV Infections; Humans; Immunoglobulins, Intravenous; Lamivudine; Male; Parvoviridae Infections; Parvovirus B19, Human; Red-Cell Aplasia, Pure; Remission Induction; Ritonavir; Saquinavir; Zidovudine | 1999 |
Persistent alterations in T-cell repertoire, cytokine and chemokine receptor gene expression after 1 year of highly active antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytokines; Female; Gene Expression; HIV Infections; HIV Protease Inhibitors; Humans; Interferon-gamma; Interleukin-10; Interleukin-13; Interleukin-2; Interleukin-4; Lamivudine; Longitudinal Studies; Male; Receptors, CCR3; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Interleukin; Receptors, Interleukin-12; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Messenger; Saquinavir; Zidovudine | 1999 |
Salvage therapy with ritonavir-saquinavir plus two nucleoside reverse transcriptase inhibitors in patients failing with amprenavir-zidovudine-lamivudine.
Topics: Adult; Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; Salvage Therapy; Saquinavir; Sulfonamides; Zidovudine | 1999 |
Avascular necrosis in HIV infection.
Topics: Adult; Anti-HIV Agents; Follow-Up Studies; HIV Infections; Humans; Lamivudine; Male; Osteonecrosis; Reverse Transcriptase Inhibitors; Saquinavir | 1999 |
[Pustulous psoriasis resistant to conventional treatment].
Topics: Adult; Antiviral Agents; Drug Resistance; Drug Therapy, Combination; HIV Seropositivity; Humans; Lamivudine; Male; Psoriasis; Saquinavir; Zidovudine | 1999 |
Saquinavir hard gel suppresses viral load insufficiently in HIV-infected patients naive to anti-retroviral therapy: a retrospective cohort study.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Controlled Clinical Trials as Topic; Denmark; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Male; Multicenter Studies as Topic; Retrospective Studies; Ritonavir; RNA, Viral; Saquinavir; Viral Load; Zidovudine | 1999 |
Incidence and predictors of virologic failure of antiretroviral triple-drug therapy in a community-based cohort.
Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Didanosine; Disease Progression; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Incidence; Indinavir; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Risk Factors; Ritonavir; RNA, Viral; Salvage Therapy; Saquinavir; Stavudine; Switzerland; Treatment Failure; Viral Load; Zalcitabine; Zidovudine | 1999 |
Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor beta chain repertoire and reduces the level of T-cell oligoclonality.
Topics: Acute Disease; Anti-HIV Agents; Clone Cells; Didanosine; Drug Administration Schedule; Drug Therapy, Combination; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indinavir; Lamivudine; Lymphocyte Activation; Polymerase Chain Reaction; RNA-Directed DNA Polymerase; Saquinavir; T-Lymphocytes, Cytotoxic; Viremia; Zidovudine | 2000 |
Predicting the duration of antiviral treatment needed to suppress plasma HIV-1 RNA.
Topics: Adult; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cohort Studies; Dideoxynucleosides; Furans; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lymph Nodes; Nelfinavir; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Stavudine; Sulfonamides; Time Factors; Viral Load; Viremia; Zidovudine | 2000 |
The efficacy and tolerability of combination antiretroviral therapy in pregnancy: infant and maternal outcome.
Topics: Adolescent; Adult; Anti-HIV Agents; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Infant; Lamivudine; Male; Nelfinavir; Nevirapine; Pregnancy; Pregnancy Outcome; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Treatment Outcome; Zidovudine | 2000 |
Decreased exposure to saquinavir in HIV-1-infected patients after long-term antiretroviral therapy including ritonavir and saquinavir.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Saquinavir; Stavudine; Time Factors | 2000 |
Drug resistance and drug combination features of the human immunodeficiency virus inhibitor, BCH-10652 [(+/-)-2'-deoxy-3'-oxa-4'-thiocytidine, dOTC].
Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Didanosine; Drug Combinations; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Molecular Structure; Mutation; Nevirapine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; T-Lymphocytes; Thionucleosides; Zidovudine | 2000 |
Mitochondrial and peroxisomal dysfunction following perinatal exposure to antiretroviral drugs.
Topics: Anti-HIV Agents; Female; HIV Infections; HIV Protease Inhibitors; Humans; Infant; Lamivudine; Male; Mitochondria; Perinatal Care; Peroxisomes; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Zidovudine | 2000 |
A multiple-site-specific heteroduplex tracking assay as a tool for the study of viral population dynamics.
Topics: Antiviral Agents; Base Sequence; Cross-Sectional Studies; DNA Probes; Drug Resistance, Microbial; Evolution, Molecular; Genetic Variation; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Longitudinal Studies; Nevirapine; Nucleic Acid Heteroduplexes; Point Mutation; Reproducibility of Results; Reverse Transcriptase Inhibitors; RNA, Viral; Saquinavir; Selection, Genetic; Sensitivity and Specificity | 2001 |
Induction-maintenance (5 --> 3 drugs) in HIV-infected patients with high viral load.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; HIV Infections; Humans; Lamivudine; Nelfinavir; Nitriles; Prospective Studies; Pyrrolidines; Remission Induction; Saquinavir; Stavudine; Treatment Outcome; Viral Load | 2000 |
Analysis of HIV-1 mutation patterns in patients failing antiretroviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Mutation; Nelfinavir; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Saquinavir; Treatment Failure; Zidovudine | 2001 |
Large hepatic mitochondrial DNA deletions associated with L-lactic acidosis and highly active antiretroviral therapy.
Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; DNA, Mitochondrial; Humans; Lamivudine; Male; Middle Aged; Saquinavir; Sequence Deletion; Stavudine | 2001 |
First clinical data presented on FortovAse.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Lamivudine; Saquinavir; Zidovudine | 1997 |
Head-to-head study of protease inhibitors.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Zidovudine | 1998 |
Data in from first head-to-head protease inhibitor.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Viral Load; Zidovudine | 1998 |
Double protease inhibitor regimens with amprenavir show promise.
Topics: Anti-HIV Agents; Carbamates; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Sulfonamides; Viral Load; Zidovudine | 1998 |
New antiretroviral strategies: interview with Marcus Conant, M.D. Interview by John S. James.
Topics: Antiviral Agents; CD4 Lymphocyte Count; DNA, Viral; Drug Therapy, Combination; HIV; HIV Infections; Humans; Isoquinolines; Lamivudine; Peripheral Nervous System Diseases; Protease Inhibitors; Quinolines; Saquinavir; Stavudine; Zalcitabine; Zidovudine | 1995 |
Protease inhibitors and prevention of cross resistance.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Carbamates; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Furans; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Isoquinolines; Lamivudine; Nelfinavir; Pyridines; Quinolines; Saquinavir; Sulfonamides; Zalcitabine; Zidovudine | 1995 |
3TC and saquinavir: we need them now.
Topics: Antiviral Agents; Drug Approval; HIV Infections; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
Conference looks at HIV drug resistance.
Topics: Antiviral Agents; Carbamates; CD4 Lymphocyte Count; Drug Resistance, Microbial; Furans; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Sulfonamides; Thiazoles; Valine; Viremia; Zalcitabine; Zidovudine | 1995 |
FDA triple header. Food and Drug Administration.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4 Lymphocyte Count; Child; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Mutation; Quinolines; Salvage Therapy; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1995 |
FDA approves 3TC and saquinavir. Food and Drug Administration.
Topics: Antiviral Agents; Drug Approval; Drug Resistance, Microbial; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine | 1995 |
FDA antiviral advisory hearings on lamivudine (Epivir, 3TC), saquinavir (Invirase), stavudine (Zerit, d4T), November 6-8. Food and Drug Administration.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Resistance, Microbial; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; Stavudine; United States; United States Food and Drug Administration; Zalcitabine | 1995 |
Potent new AIDS drugs underscore promise of combination therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; CD4 Lymphocyte Count; Drug Approval; Drug Resistance; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Seropositivity; Humans; Isoquinolines; Lamivudine; Quinolines; Saquinavir; United States; United States Food and Drug Administration; Zalcitabine; Zidovudine | 1996 |
Europe out of step with the US.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Didanosine; Drug Costs; Europe; HIV Protease Inhibitors; Humans; Isoquinolines; Lamivudine; Quinolines; Ritonavir; Saquinavir; Thiazoles; United States; Valine; Zalcitabine; Zidovudine | 1996 |
Nipping HIV in the bud.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Didanosine; DNA, Viral; Drug Resistance, Microbial; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Isoquinolines; Lamivudine; Pyridines; Quinolines; Ritonavir; Saquinavir; Stavudine; Thiazoles; Valine; Virus Replication; Zalcitabine; Zidovudine | 1996 |
ICAAC update.
Topics: Acetamides; Acetophenones; Anti-HIV Agents; Carbamates; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; Drugs, Investigational; Furans; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Sulfonamides; Viral Load | 1996 |
Spring cleaning in trial land.
Topics: Anti-HIV Agents; Brazil; CD4 Lymphocyte Count; Clinical Trials as Topic; Disease Progression; Drug Resistance, Microbial; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Saquinavir; Stavudine; United States; Viral Load; Zidovudine | 1997 |
ACTG 343: three drugs better than two for maintaining HIV suppression.
Topics: AIDS Vaccines; Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Lamivudine; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Viral Load; Zidovudine | 1998 |
New ways to take old drugs.
Topics: Anti-HIV Agents; Biological Availability; Drug Combinations; Drug Storage; HIV Infections; Humans; Lamivudine; Saquinavir; Zidovudine | 1998 |
Any toxic relief in sight? The induction/maintenance approach to therapy.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Nelfinavir; Saquinavir; Stavudine; T-Lymphocytes; Viral Load; Virus Replication | 1998 |
Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs.
Topics: Amino Acid Sequence; Anti-HIV Agents; Base Sequence; DNA, Viral; Drug Resistance, Microbial; Drug Resistance, Multiple; Evolution, Molecular; Genetic Heterogeneity; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Molecular Sequence Data; Mutagenesis, Insertional; Phylogeny; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Time Factors; Zidovudine | 2001 |
[HIV-HBV coinfection and the liver].
Topics: Biopsy; Didanosine; Drug Therapy, Combination; Hepatitis B; HIV Infections; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Ritonavir; Saquinavir; Stavudine | 2001 |
Gynaecomastia associated with combination antiretroviral therapy including protease inhibitors for human immunodeficiency virus infection.
Topics: Anti-HIV Agents; Diagnosis, Differential; Drug Therapy, Combination; Gynecomastia; HIV Infections; HIV Protease Inhibitors; HIV-1; Homosexuality, Male; Humans; Lamivudine; Male; Middle Aged; Ritonavir; Saquinavir; Stavudine | 1999 |
[Cytomegalovirus retinitis after highly active antiretroviral therapy: a case report].
Topics: Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cytomegalovirus Retinitis; Didanosine; Ganciclovir; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Retinal Hemorrhage; Reverse Transcriptase Inhibitors; Risk; Saquinavir; Stavudine; Substance Abuse, Intravenous; Zidovudine | 2002 |
Highlights of the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).
Topics: Adenine; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Drug Therapy; Epoetin Alfa; Erythropoietin; Hepatitis C; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins; Saquinavir; Tenofovir; Zidovudine | 2002 |
Rheumatoid arthritis after 9 years of human immunodeficiency virus infection: possible contribution of tritherapy.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Arthritis, Reactive; HIV; HIV Infections; Humans; Immunocompromised Host; Lamivudine; Male; Saquinavir; Stavudine; Treatment Outcome | 2002 |
Rapidly progressive human herpesvirus 8-associated solid anaplastic lymphoma in a patient with AIDS--associated Kaposi sarcoma.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Cyclophosphamide; Disease Progression; Doxorubicin; Epstein-Barr Virus Infections; Fatal Outcome; Gastrointestinal Neoplasms; Herpesviridae Infections; Herpesvirus 4, Human; Herpesvirus 8, Human; HIV-1; Humans; Lamivudine; Lymphoma, AIDS-Related; Lymphoma, Large B-Cell, Diffuse; Male; Neoplasms, Second Primary; Prednisone; Ritonavir; Saquinavir; Sarcoma, Kaposi; Skin Neoplasms; Stavudine; Tumor Virus Infections; Vincristine | 2003 |
Hypertriglyceridemia and hypercholesterolemia in human immunodeficiency virus-1-infected children treated with protease inhibitors.
Topics: Adolescent; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; Female; Follow-Up Studies; HIV Infections; HIV Protease Inhibitors; Humans; Hypercholesterolemia; Hypertriglyceridemia; Infant; Lamivudine; Male; Ritonavir; Saquinavir; Zidovudine | 2006 |
Lung cancer as an immune reconstitution disease in an HIV-1 positive man receiving HAART.
Topics: Adult; Antiretroviral Therapy, Highly Active; Carcinoma, Small Cell; Fatal Outcome; HIV Seropositivity; Humans; Lamivudine; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Ritonavir; Saquinavir; Zidovudine | 2006 |
First use of tamoxifen in an HIV patient with encapsulating peritoneal sclerosis.
Topics: Anti-HIV Agents; Drug Therapy, Combination; Estrogen Antagonists; Glucocorticoids; HIV Infections; Humans; Kidney Failure, Chronic; Lamivudine; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneal Diseases; Saquinavir; Sclerosis; Tamoxifen; Zidovudine | 2007 |
Once-daily treatment with saquinavir mesylate (2000 mg) and ritonavir (100 mg) together with a fixed-dose combination of abacavir/lamivudine (600/300 mg) or tenofovir/emtricitabine (245/200 mg) in HIV-1-infected patients.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Area Under Curve; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Plasma; Ritonavir; RNA, Viral; Saquinavir; Tenofovir; Treatment Outcome; Viral Load | 2009 |
Impact of antiretroviral pressure on selection of primary human immunodeficiency virus type 1 envelope sequences in vitro.
Topics: Amino Acid Sequence; Anti-HIV Agents; Base Sequence; Cyclohexanes; DNA, Viral; Genetic Variation; Genotype; Glycosylation; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Lamivudine; Maraviroc; Molecular Sequence Data; Phylogeny; Pyrrolidinones; Raltegravir Potassium; Receptors, CCR5; Receptors, CXCR4; Saquinavir; Sequence Analysis, DNA; Triazoles; Viral Tropism | 2013 |
Headache in an HIV-Positive Patient: Dangerous Interaction.
Topics: Adult; Anti-HIV Agents; Anticoagulants; Cilostazol; Cytochrome P-450 CYP3A Inhibitors; Dideoxynucleosides; Drug Combinations; Drug Interactions; Enoxaparin; Ergotamine; Ergotism; Headache; HIV Infections; Humans; Ischemia; Lamivudine; Lower Extremity; Male; Nitroglycerin; Ritonavir; Saquinavir; Tetrazoles; Tibial Arteries; Ultrasonography, Doppler, Color; Vasoconstrictor Agents; Vasodilator Agents | 2018 |