laminaran and pimagedine

laminaran has been researched along with pimagedine* in 1 studies

Other Studies

1 other study(ies) available for laminaran and pimagedine

Article	Year
Macrophage cytotoxicity against murine meth A sarcoma involves nitric oxide-mediated apoptosis. Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3 We have studied the cytotoxic effect of stimulated macrophages on Meth A tumor cells in vitro. When stimulated with interferon-gamma and soluble beta-1,3-D-glucan, macrophages exerted cytotoxicity towards syngeneic Meth A tumor cells. This cytotoxicity was associated with a high level of nitric oxide production. Both cell death and nitric oxide production were significantly inhibited by the addition of aminoguanidine, a specific inhibitor of inducible nitric oxide synthase (iNOS), to the culture medium. The cytotoxic effect was accompanied by internucleosomal cleavage of DNA as shown by electrophoresis and DNA fragmentation assay. Topics: Animals; Apoptosis; beta-Glucans; Cells, Cultured; Coculture Techniques; Female; Glucans; Guanidines; Interferon Inducers; Interferon-gamma; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Electron; Microscopy, Electron, Scanning; Nitric Oxide; Nitrites; Nitroprusside; Recombinant Proteins; Sarcoma, Experimental; Tumor Cells, Cultured	1996

Article

Year

Macrophage cytotoxicity against murine meth A sarcoma involves nitric oxide-mediated apoptosis.

Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3

We have studied the cytotoxic effect of stimulated macrophages on Meth A tumor cells in vitro. When stimulated with interferon-gamma and soluble beta-1,3-D-glucan, macrophages exerted cytotoxicity towards syngeneic Meth A tumor cells. This cytotoxicity was associated with a high level of nitric oxide production. Both cell death and nitric oxide production were significantly inhibited by the addition of aminoguanidine, a specific inhibitor of inducible nitric oxide synthase (iNOS), to the culture medium. The cytotoxic effect was accompanied by internucleosomal cleavage of DNA as shown by electrophoresis and DNA fragmentation assay.

Topics: Animals; Apoptosis; beta-Glucans; Cells, Cultured; Coculture Techniques; Female; Glucans; Guanidines; Interferon Inducers; Interferon-gamma; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Electron; Microscopy, Electron, Scanning; Nitric Oxide; Nitrites; Nitroprusside; Recombinant Proteins; Sarcoma, Experimental; Tumor Cells, Cultured

1996