Page last updated: 2024-08-17

lactose and stearic acid

lactose has been researched along with stearic acid in 139 studies

Research

Studies (139)

TimeframeStudies, this research(%)All Research%
pre-19904 (2.88)18.7374
1990's11 (7.91)18.2507
2000's28 (20.14)29.6817
2010's87 (62.59)24.3611
2020's9 (6.47)2.80

Authors

AuthorsStudies
Augsburger, LL; Marshall, K; Shah, KB1
Bolhuis, GK; Lerk, CF; Smallenbroek, AJ1
Ghaly, ES; Malavé, MI; Martí, A; Rivera, WJ1
Armstrong, NA; Barnett, MI; Britten, JR1
Drennen, JK; Wargo, DJ1
Flachowsky, G; Lebzien, P; Möckel, P; Wagner, K1
Bertoni, M; Bolhuis, GK; Bonferoni, CM; Caramella, C; Ferrari, F; Rossi, S1
Eliasen, H; Kristensen, HG; Schaefer, T2
Ghaly, ES; Vargas, CI1
Badiello, R; Ceschel, GC; Maffei, P1
Vashchuk, VV1
Franceschinis, E; Moneghini, M; Perissutti, B; Voinovich, D1
Matsuda, Y; Otsuka, M; Sato, M1
Arratia, P; Duong, NH; Lange, A; Muzzio, F; Reynolds, S; Timmermans, J1
Mraz, FR; Waibel, PE1
Tove, SB1
Filipovic-Grcic, J; Franceschinis, E; Grassi, M; Perissutti, B; Voinovich, D1
Bowtell, RW; Köckenberger, W; MacRae, RJ; Melia, CD; Ross, AC; Stevens, HN; Sutch, JC1
Lovato, D; Marchitto, L; Martelli, S; Palmieri, GF; Zanchetta, A1
Muzíková, J; Páleník, L1
Jiang, RG; Liu, H; Pan, WS; Wang, CL; Wang, LQ; Zhang, PW1
Gray, A; Hasenzahl, S; Jonat, S; Schmidt, PC1
Lee, J2
Jahn, T; Steffens, KJ1
Cobb, J; Saracovan, I; Swaminathan, V1
Corrigan, OI; Killen, BU1
Otsuka, M; Yamane, I1
Bunker, MJ; Davies, MC; James, MB; Roberts, CJ1
Ando, M; Kojima, S; Nabeshima, T; Nakayama, Y; Ozeki, Y1
Faqih, A; Levin, M; Llusa, M; Mehrotra, A; Muzzio, FJ1
Faqih, AM; Hammond, SV; Mehrotra, A; Muzzio, FJ1
Davies, PN; Newton, JM; Podczeck, F; Worthington, HE1
Ando, M; Nakayama, Y; Shimizu, K1
Heilweil, EJ; Hussain, AS; Khan, MA; Wu, H1
Frei, M; Guchardi, R; John, E; Kaerger, JS1
Kojima, M; Kuno, Y; Nakagami, H; Terada, K; Yonemochi, E1
Kumon, M; Kusai, A; Machida, S; Suzuki, M; Terada, K; Yonemochi, E1
Alvarez-Nunez, FA; Chang, CK; Magnusson, LE; Rinella, JV; Sueda, K1
Badillo, N; Ghaly, ES1
Irisawa, Y; Okimoto, K; Okuda, Y; Osawa, T; Yamashita, S1
Armstrong, B; Larson, I; Morton, DA; Stewart, PJ; Zhou, Q1
Bariya, SH; Gohel, M1
Heng, PW; Karande, AD; Liew, CV3
Huang, WH; Liu, L; Wong, YF; Wu, H; Yang, ZJ; Zhao, ZZ1
Dittgen, M; Jouma, M; Neubert, RH; Rajab, M1
Antikainen, O; Colarte, AI; Heinämäki, J; Mir, VG; Nieto, OM; Revoredo, OB; Sandler, N; Yliruusi, J1
Kushner, J; Moore, F1
Bertrand, F; Chaouki, J; Perrault, M1
Cuitino, A; Lewis, D; Mendez, R; Michniak-Kohn, B; Muzzio, F; Pingali, K1
Colón, Y; Johnson-Restrepo, B; Romañach, RJ; Ropero, J1
Amigo, JM; Coello, J; Franch-Lage, F; Maspoch, S; Skibsted, E1
Das, S; Denman, JA; Gengenbach, T; Larson, I; Morton, DAV; Qu, L; Stewart, PJ; Zhang, H; Zhou, QT1
Denman, JA; Gengenbach, T; Larson, I; Morton, DA; Qu, L; Stewart, PJ; Zhou, QT1
Carvajal, MT; Ely, DR1
Das, SC; Larson, I; Morton, DA; Stewart, PJ; Zhou, Q1
Dawes, J; Gamble, JF; Greenwood, R; Robbins, P; Tobyn, M1
Kumar, RV; Sinha, VR1
Heng, PW; Ng, KY; Samanta, AK1
Early, W; Gao, Z; Jerzewski, R; Levin, M; Miller, R; Nesarikar, VV; Pandey, P; Patel, C; Sprockel, O; Vatsaraj, N1
Kushner, J1
Elkes, R; Jin, L; Lalloo, AK; McConnell, EL; Seiler, C; Wu, Y1
de Monte, M; Diot, P; Guillemain, J; Guillon, A; Montharu, J; Roseau, G; Schubnel, V; Vecellio, L1
Abebe, A; Akseli, I; Cuitiño, AM; Kottala, N; Nikfar, F; Sprockel, O1
Busignies, V; Diarra, H; Mazel, V; Tchoreloff, P1
Das, SC; Stewart, PJ1
Abebe, A; Bergum, J; Cuitiño, AM; Kottala, N; Nikfar, F; Sprockel, O1
Aher, AA; Desai, SS; Kadaskar, PT1
Avalle, P; Jastrzemska, A; Pritchard, J; Pygall, SR1
Borchert, S; Hoehe, W; Järvinen, K; Järvinen, M; Juuti, M; Poutiainen, S1
Ilič, I; Kása, P; Papós, K; Pintye-Hódi, K; Sovány, T; Srčič, S1
Möschwitzer, JP; Müller, RH; Salazar, J1
Cetinkaya, C; Hancock, BC; Krishna Prasad Vallabh, C; Saeedi Vahdat, A1
Drake, KR; Newton, JM; Podczeck, F1
Bodmeier, R; Hosseini, A; Körber, M1
Muzzio, FJ; Osorio, JG1
Mužíková, J; Sináglová, P1
Anderson, CA; de Juan, A; Drennen, JK; Igne, B; Jaumot, J1
Heng, PW; Ng, KY; Samanta, AK; Wang, L1
Agarwal, K; Hicks, I; Kane, A; Kathiria, L; Kushner, J; Langdon, BA; Li, F; Ranade, G; Song, D1
Guadalupe Sánchez-González, E; Jesús Hernández-Abad, V; Jung Cook, H; Yépez-Mulia, L1
Gamble, JF; Hoffmann, M; Hughes, H; Hutchins, P; Tobyn, M1
Anderson, CA; de Juan, A; Drennen, JK; Igne, B; Jaumot, J; Lallemand, J; Preys, S1
de Villiers, MM; Derdour, L; Huang, J; Hussain, MA; Qian, F; Yu, L; Zhang, SW1
Colon, Y; Mateo-Ortiz, D; Méndez, R; Romañach, RJ1
Kushner, J; Schlack, H1
Allen, MS; Lock, AL; Piantoni, P1
Mashru, R; Mittal, K; Patadia, R; Vora, C1
Badal Tejedor, M; Millqvist-Fureby, A; Nordgren, N; Rutland, MW; Schuleit, M1
Alcalà, M; Blanco, M; Cárdenas, V; Cordobés, M1
Onishi, H; Sakata, O; Yumoto, K1
Gajdziok, J; Vetchý, D; Vraníková, B1
Gamble, JF; Hoffmann, M; Tobyn, M; Wray, PS1
Boiret, M; de Juan, A; Ginot, YM; Gorretta, N; Roger, JM1
Kagawa, Y; Miyawaki, K; Miyazaki, Y; Uchino, T1
Edge, S; Lewis, D; Price, R; Shur, J; Singh, D; Woollam, G; Young, PM1
Busignies, V; Croquelois, B; Diarra, H; Girardot, J; Guerard, S; Kopp, JB; Mazel, V; Tchoreloff, P1
Anbalagan, P; Heng, PWS; Liew, CV; Sarkar, S1
Kerschhaggl, M; Khinast, JG; Pucher, I; Sacher, S; Scheibelhofer, O; Wahl, PR1
Dohi, M; Hakomori, T; Momose, W; Noguchi, S; Sato, S; Terada, K; Yamashita, K1
Lau, M; Traini, D; Young, PM2
Govindarajan, R; Koranne, S; Suryanarayanan, R1
Crean, AM; Crowley, ME; Hayes, K; Hegarty, A; Kiernan, L; McAuliffe, MAP; O'Mahony, GE1
Paul, S; Sun, CC1
Hayashi, Y; Hirai, D; Kosugi, A; Kumada, S; Oishi, T; Onuki, Y; Shirotori, K; Takayama, K; Tsuji, T1
Hosaka, S; Tokunaga, Y1
Imanidis, G; Jetzer, MW; Morrical, BD; Schneider, M1
Callegari, G; Drazer, G; Liu, Z; Muzzio, F; Wang, Y1
Escotet-Espinoza, MS; Ierapetritou, MG; Muzzio, FJ; Singh, R; Vadodaria, S1
Leung, LY; Mao, C; Uzondu, B; Yang, CY1
Church, T; Lewis, D; Traini, D; Tweedie, A; Yeung, S; Young, PM1
Hayashi, Y; Kosugi, A; Miura, T; Onuki, Y; Takayama, K1
Brinz, T; Khinast, J; Otterbach, S; Wagner, B1
Aubert, A; Bataille, B; Baylac, G; Lefevre, P; Sanchez-Ballester, N; Sharkawi, T; Soulairol, I; Tarlier, N1
Björn, IN; Nguyen, D; Remmelgas, J; Thalberg, K; van Wachem, B1
Goh, HP; Heng, PWS; Liew, CV2
Boulas, P; Dun, J; Lin, Y; Osei-Yeboah, F; Sun, CC2
Anderson, CA; Drennen, JK; Hossain, MN; Igne, B1
De Beer, T; De Leersnyder, F; Kumar, A; Vanhoorne, V; Vervaet, C1
Carnahan, SL; Hirsh, DA; Hung, I; Lubach, JW; Nagapudi, K; Rossini, AJ; Wijesekara, AV1
Kleinebudde, P; Radtke, J; Wiedey, R1
Cartwright, JJ; Mundozah, AL; Omar, CS; Salman, AD; Tridon, CC; Yang, J1
Baltodano Viales, E; Calvo Guzmán, B; Carazo Berrocal, G; Castillo Henríquez, L; Madrigal Redondo, G; Vargas Zúñiga, R1
Nesarikar, V; Phanse, R; Reddy, JP1
Chan, HK; Chang, RYK; Chrzanowski, W; Khanal, D; Morales, S1
Hoag, SW; Ibrahim, A; Wang, T1
Kushida, K; Matsuda, Y; Nakamura, H; Ohsaki, S; Watano, S1
Rantanen, J; Skelbæk-Pedersen, AL; Vilhelmsen, TK; Wallaert, V1
Méndez, R; Romañach, RJ; Sierra-Vega, NO1
Kashiwagura, Y; Kurashima, H; Namiki, N; Tanaka, S; Uchida, S1
Berecka-Rycerz, A; Fornal, E; Granica, S; Gumieniczek, A; Żyżyńska-Granica, B1
Guan, J; He, X; Li, J; Ma, S; Mao, S; Sun, Y; Zhang, X1
Imole, O; Marek, K; Mehta, M; Peters, H; van der Wel, P; Welle, A1

Reviews

2 review(s) available for lactose and stearic acid

ArticleYear
Methods for reduction of cohesive forces between carrier and drug in DPI formulation.
    Drug development and industrial pharmacy, 2013, Volume: 39, Issue:11

    Topics: Adhesiveness; Administration, Inhalation; Chemical Phenomena; Drug Carriers; Drug Compounding; Drug Stability; Dry Powder Inhalers; Excipients; Humans; Lactose; Lung; Polyethylene Glycols; Powders; Respiratory System Agents; Stearic Acids; Tissue Distribution

2013
From single excipients to dual excipient platforms in dry powder inhaler products.
    International journal of pharmaceutics, 2016, Dec-05, Volume: 514, Issue:2

    Topics: Administration, Inhalation; Drug Compounding; Dry Powder Inhalers; Excipients; Humans; Lactose; Particle Size; Respiratory Therapy; Stearic Acids; Surface Properties

2016

Trials

1 trial(s) available for lactose and stearic acid

ArticleYear
[The use of the catalase P-47 preparation for treating long-term nonhealing wounds and trophic ulcers].
    Klinicheskaia khirurgiia, 1993, Issue:1

    Topics: Aged; Catalase; Chronic Disease; Drug Combinations; Hexachlorophene; Humans; Lactose; Middle Aged; Stearic Acids; Time Factors; Ulcer; Wound Healing

1993

Other Studies

136 other study(ies) available for lactose and stearic acid

ArticleYear
An investigation of some factors influencing plug formation and fill weight in a dosing disk-type automatic capsule-filling machine.
    Journal of pharmaceutical sciences, 1986, Volume: 75, Issue:3

    Topics: Capsules; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Stearic Acids; Technology, Pharmaceutical

1986
Interaction of tablet disintegrants and magnesium stearate during mixing I: Effect on tablet disintegration.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:12

    Topics: Aspirin; Calcium Phosphates; Drug Compounding; Excipients; Hardness; Lactose; Solubility; Starch; Stearic Acids; Tablets

1981
Controlled release of theophylline from inert matrices: effect of channeling material on release rate.
    Puerto Rico health sciences journal, 1993, Volume: 12, Issue:4

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Delivery Systems; Drug Design; Lactose; Stearic Acids; Tablets; Theophylline; Time Factors

1993
Studies on powder plug formation using a simulated capsule filling machine.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:3

    Topics: Drug Compounding; Lactose; Starch; Stearic Acids; Tablets

1996
Near-infrared spectroscopic characterization of pharmaceutical powder blends.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:11

    Topics: Carboxymethylcellulose Sodium; Hydrochlorothiazide; Lactose; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical; Time Factors

1996
Influence of duodenal infusion of nicotinic acid on the milk fat composition of dairy cows.
    Archiv fur Tierernahrung, 1997, Volume: 50, Issue:3

    Topics: Administration, Oral; Animals; Catheterization; Cattle; Chromatography, Gas; Dose-Response Relationship, Drug; Duodenum; Fatty Acids; Female; Intestinal Absorption; Lactose; Lipid Metabolism; Lipids; Milk; Niacin; Niacinamide; Oleic Acid; Proteins; Stearic Acids

1997
Dissolution enhancement of an insoluble drug by physical mixture with a superdisintegrant: optimization with a simplex lattice design.
    Pharmaceutical development and technology, 1996, Volume: 1, Issue:2

    Topics: Anti-Inflammatory Agents; Calcium Phosphates; Carboxymethylcellulose Sodium; Excipients; Hardness Tests; Kinetics; Lactose; Prednisone; Regression Analysis; Solubility; Stearic Acids; Tablets

1996
Electrostatic charging during a melt agglomeration process.
    International journal of pharmaceutics, 1999, Jul-05, Volume: 184, Issue:1

    Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Excipients; Glycerides; Humidity; Lactose; Polyethylene Glycols; Static Electricity; Stearic Acids; Viscosity

1999
Growth mechanisms in melt agglomeration with a low viscosity binder.
    International journal of pharmaceutics, 1999, Sep-20, Volume: 186, Issue:2

    Topics: Chemistry, Pharmaceutical; Image Processing, Computer-Assisted; Lactose; Microscopy, Electron, Scanning; Particle Size; Porosity; Stearic Acids; Temperature; Viscosity; Water

1999
Kinetic release of theophylline from hydrophilic swellable matrices.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:9

    Topics: Administration, Oral; Excipients; Lactose; Methylcellulose; Models, Theoretical; Oxazines; Polymers; Solubility; Solvents; Stearic Acids; Tablets; Theophylline; Time Factors

1999
Optimization of a tablet containing chlorthalidone.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:11

    Topics: Algorithms; Antihypertensive Agents; Cellulose; Chlorthalidone; Excipients; Hardness Tests; Lactose; Models, Theoretical; Pressure; Stearic Acids; Tablets

1999
Melt pelletization in high shear mixer using a hydrophobic melt binder: influence of some apparatus and process variables.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2001, Volume: 52, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Hydrophobic and Hydrophilic Interactions; Lactose; Stearic Acids; Tablets; Technology, Pharmaceutical

2001
Comparative evaluation of tableting compression behaviors by methods of internal and external lubricant addition: inhibition of enzymatic activity of trypsin preparation by using external lubricant addition during the tableting compression process.
    AAPS pharmSci, 2001, Volume: 3, Issue:3

    Topics: Algorithms; Cellulose; Excipients; Hardness; Lactose; Lubrication; Solutions; Stearic Acids; Tablets; Technology, Pharmaceutical; Trypsin

2001
A homogeneity study using NIR spectroscopy: tracking magnesium stearate in Bohle bin-blender.
    Drug development and industrial pharmacy, 2003, Volume: 29, Issue:6

    Topics: Cellulose; Excipients; Lactose; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical

2003
CALCIUM, STRONTIUM AND PHOSPHORUS UTILIZATION BY CHICKS AS INFLUENCED BY NUTRITIONAL AND ENDOCRINE VARIATIONS.
    The Journal of nutrition, 1964, Volume: 84, Issue:1

    Topics: Alkaline Phosphatase; Animals; Blood; Calcium; Calcium, Dietary; Chickens; Diet; Estradiol; Glucose; Hydrocortisone; Lactose; Pharmacology; Phosphorus; Poultry; Research; Sorbitol; Stearic Acids; Strontium; Testosterone; Vitamin D; Vitamins

1964
TOXICITY OF SATURATED FAT.
    The Journal of nutrition, 1964, Volume: 84

    Topics: Carbohydrates; Cholesterol; Dietary Fats; Fatty Acids; Lactose; Mice; Palmitic Acid; Pharmacology; Research; Stearic Acids; Toxicology

1964
Theoretical and experimental study on theophylline release from stearic acid cylindrical delivery systems.
    Journal of controlled release : official journal of the Controlled Release Society, 2003, Oct-30, Volume: 92, Issue:3

    Topics: Algorithms; Computer Simulation; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Electron Probe Microanalysis; Kinetics; Lactose; Models, Theoretical; Polyethylene Glycols; Pressure; Solubility; Spectrophotometry, Ultraviolet; Stearic Acids; Theophylline

2003
Investigating the coating-dependent release mechanism of a pulsatile capsule using NMR microscopy.
    Journal of controlled release : official journal of the Controlled Release Society, 2003, Oct-30, Volume: 92, Issue:3

    Topics: Calcium Phosphates; Capsules; Carboxymethylcellulose Sodium; Cellulose; Delayed-Action Preparations; Drug Delivery Systems; Excipients; Image Processing, Computer-Assisted; Kinetics; Lactose; Magnetic Resonance Imaging; Propranolol; Solvents; Spectrophotometry, Ultraviolet; Stearic Acids; Water

2003
Evaluation of the mixing effectiveness of a new powder mixer.
    Drug development and industrial pharmacy, 1998, Volume: 24, Issue:1

    Topics: Cellulose; Drug Compounding; Excipients; Hardness; Lactose; Microscopy, Electron, Scanning; Powders; Quality Control; Salicylic Acid; Stearic Acids; Time Factors

1998
[A study of the properties of compacts from a mixed dry binder on the base of alpha-lactose monohydrate and microcrystalline cellulose].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2005, Volume: 54, Issue:3

    Topics: Cellulose; Compressive Strength; Lactose; Pharmaceutic Aids; Stearic Acids; Tablets; Tensile Strength

2005
[Effect of surface modification on surface energy of lactose and performance of dry powder inhalations].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:4

    Topics: Administration, Inhalation; Chromatography, Gas; Drug Carriers; Interferon alpha-2; Interferon-alpha; Lactose; Particle Size; Powders; Recombinant Proteins; Stearic Acids; Surface Properties; Talc; Technology, Pharmaceutical

2005
Influence of compacted hydrophobic and hydrophilic colloidal silicon dioxide on tableting properties of pharmaceutical excipients.
    Drug development and industrial pharmacy, 2005, Volume: 31, Issue:7

    Topics: Cellulose; Chemistry, Pharmaceutical; Colloids; Drug Compounding; Drug Stability; Excipients; Hydrophobic and Hydrophilic Interactions; Lactose; Silicon Dioxide; Starch; Stearic Acids; Tablets; Tensile Strength; Water

2005
Intrinsic adhesion properties of poly(vinyl pyrrolidone) to pharmaceutical materials: humidity effect.
    Macromolecular bioscience, 2005, Nov-04, Volume: 5, Issue:11

    Topics: Adhesiveness; Humidity; Hydrophobic and Hydrophilic Interactions; Lactose; Pharmaceutic Aids; Povidone; Stearic Acids

2005
Press chamber coating as external lubrication for high speed rotary presses: lubricant spray rate optimization.
    Drug development and industrial pharmacy, 2005, Volume: 31, Issue:10

    Topics: Calibration; Drug Compounding; Equipment Design; Excipients; Lactose; Lubrication; Mannitol; Sorbitol; Spectrophotometry, Atomic; Starch; Stearic Acids; Tablets; Tensile Strength

2005
Measurement of the surface energy of lubricated pharmaceutical powders by inverse gas chromatography.
    International journal of pharmaceutics, 2006, Apr-07, Volume: 312, Issue:1-2

    Topics: Cellulose; Chromatography, Gas; Excipients; Lactose; Lubrication; Powders; Stearic Acids; Surface Properties

2006
Effect of soluble filler on drug release from stearic acid based compacts.
    International journal of pharmaceutics, 2006, Jun-19, Volume: 316, Issue:1-2

    Topics: Benzoic Acid; Drug Carriers; Drug Compounding; Drug Design; Insulin; Kinetics; Lactose; Solubility; Stearic Acids

2006
Prediction of tablet hardness based on near infrared spectra of raw mixed powders by chemometrics.
    Journal of pharmaceutical sciences, 2006, Volume: 95, Issue:7

    Topics: Cellulose; Dipyrone; Drug Compounding; Excipients; Hardness; Lactose; Lubrication; Models, Chemical; Powders; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Starch; Stearic Acids; Tablets

2006
A nanoscale study of particle friction in a pharmaceutical system.
    International journal of pharmaceutics, 2006, Nov-15, Volume: 325, Issue:1-2

    Topics: Drug Combinations; Drug Stability; Friction; Lactose; Microscopy, Atomic Force; Nanotechnology; Particle Size; Pharmaceutical Preparations; Polytetrafluoroethylene; Stearic Acids; Surface Properties; Technology, Pharmaceutical; Zanamivir

2006
Development and evaluation of a novel dry-coated tablet technology for pellets as a substitute for the conventional encapsulation technology.
    International journal of pharmaceutics, 2007, May-04, Volume: 336, Issue:1

    Topics: Cellulose; Delayed-Action Preparations; Drug Compounding; Elasticity; Food Coloring Agents; Lactose; Particle Size; Pressure; Stearic Acids; Sulfonamides; Tablets, Enteric-Coated; Tamsulosin; Technology, Pharmaceutical; Tensile Strength

2007
Influence of shear intensity and total shear on properties of blends and tablets of lactose and cellulose lubricated with magnesium stearate.
    International journal of pharmaceutics, 2007, May-24, Volume: 336, Issue:2

    Topics: Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Hardness; Lactose; Lubrication; Powders; Rheology; Stearic Acids; Surface Properties; Tablets

2007
Effect of moisture and magnesium stearate concentration on flow properties of cohesive granular materials.
    International journal of pharmaceutics, 2007, May-24, Volume: 336, Issue:2

    Topics: Cellulose; Chemical Phenomena; Chemistry, Physical; Drug Stability; Excipients; Hardness; Humidity; Lactose; Lubrication; Powders; Rheology; Solubility; Stearic Acids; Surface Properties; Technology, Pharmaceutical

2007
The determination of the mechanical strength of tablets of different shapes.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2007, Volume: 67, Issue:1

    Topics: Cellulose; Drug Compounding; Excipients; Hardness; Hardness Tests; Lactose; Particle Size; Pressure; Stearic Acids; Tablets

2007
Nanoscopic friction behavior of pharmaceutical materials.
    International journal of pharmaceutics, 2007, Aug-01, Volume: 340, Issue:1-2

    Topics: Acetaminophen; Adhesiveness; Chemistry, Pharmaceutical; Dosage Forms; Drug Compounding; Excipients; Friction; Fumarates; Kinetics; Lactose; Microscopy, Atomic Force; Models, Chemical; Nanotechnology; Stainless Steel; Stearic Acids; Surface Properties; Technology, Pharmaceutical

2007
Characterization of tableting using the OSDRC system.
    Pharmaceutical research, 2007, Volume: 24, Issue:10

    Topics: Cellulose; Compressive Strength; Lactose; Phenacetin; Porosity; Powders; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical

2007
Process analytical technology (PAT): effects of instrumental and compositional variables on terahertz spectral data quality to characterize pharmaceutical materials and tablets.
    International journal of pharmaceutics, 2007, Oct-01, Volume: 343, Issue:1-2

    Topics: Cellulose; Excipients; Lactose; Pharmaceutical Preparations; Spectrum Analysis; Starch; Stearic Acids; Tablets; Technology, Pharmaceutical; Theophylline

2007
Influence of fine lactose and magnesium stearate on low dose dry powder inhaler formulations.
    International journal of pharmaceutics, 2008, Feb-04, Volume: 348, Issue:1-2

    Topics: Administration, Inhalation; Algorithms; Bronchodilator Agents; Drug Stability; Ethanolamines; Excipients; Formoterol Fumarate; Lactose; Light; Mechanics; Particle Size; Pharmaceutical Vehicles; Powders; Scattering, Radiation; Sonication; Stearic Acids

2008
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 69, Issue:3

    Topics: Absorption; Administration, Oral; Chemical Phenomena; Chemistry, Physical; Excipients; Fumarates; Hardness; Lactose; Lubricants; Porosity; Solubility; Stearic Acids; Sugar Alcohols; Surface Properties; Tablets; Talc; Water; Xylitol

2008
Application and mechanism of inhalation profile improvement of DPI formulations by mechanofusion with magnesium stearate.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:5

    Topics: Adhesiveness; Administration, Inhalation; Algorithms; Chemistry, Pharmaceutical; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Excipients; Lactose; Microscopy, Electron, Scanning; Powders; Spectrophotometry, Ultraviolet; Stearic Acids; Surface Properties

2008
Roller compaction, granulation and capsule product dissolution of drug formulations containing a lactose or mannitol filler, starch, and talc.
    AAPS PharmSciTech, 2008, Volume: 9, Issue:2

    Topics: Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Compounding; Drug Stability; Excipients; Gelatin; Humidity; Lactose; Mannitol; Models, Chemical; Particle Size; Powders; Rheology; Solubility; Starch; Stearic Acids; Talc; Technology, Pharmaceutical; Temperature; Tensile Strength; Time Factors

2008
In vitro evaluation of theophylline matrices using xyloglucan.
    Pharmaceutical development and technology, 2008, Volume: 13, Issue:6

    Topics: Bronchodilator Agents; Buffers; Calcium Phosphates; Cellulose; Delayed-Action Preparations; Excipients; Glucans; Hydrochloric Acid; Lactose; Rotation; Stearic Acids; Theophylline; Water; Xylans

2008
A new formulation for orally disintegrating tablets using a suspension spray-coating method.
    International journal of pharmaceutics, 2009, Dec-01, Volume: 382, Issue:1-2

    Topics: Administration, Oral; Chemistry, Pharmaceutical; Excipients; Hardness; Kinetics; Lactose; Linear Models; Mannitol; Models, Chemical; Particle Size; Porosity; Povidone; Silicic Acid; Solubility; Starch; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Trehalose

2009
Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:2

    Topics: Algorithms; Chemistry, Pharmaceutical; Desiccation; Drug Compounding; Excipients; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders; Rheology; Stearic Acids

2010
Advanced formulation design of venlafaxine hydrochloride coated and triple-layer tablets containing hypromellose.
    Pharmaceutical development and technology, 2009, Volume: 14, Issue:6

    Topics: Algorithms; Antidepressive Agents, Second-Generation; Biological Availability; Cellulose; Chemistry, Pharmaceutical; Cyclohexanols; Delayed-Action Preparations; Drug Stability; Ethanol; Excipients; Hypromellose Derivatives; Lactose; Methylcellulose; Models, Chemical; Models, Statistical; Stearic Acids; Tablets, Enteric-Coated; Venlafaxine Hydrochloride; Water

2009
In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy.
    International journal of pharmaceutics, 2010, Feb-15, Volume: 386, Issue:1-2

    Topics: Calibration; Cellulose; Chemistry, Pharmaceutical; Chlorpheniramine; Equipment Design; Excipients; Lactose; Least-Squares Analysis; Particle Size; Powders; Reproducibility of Results; Spectroscopy, Near-Infrared; Stearic Acids; Surface Properties; Technology, Pharmaceutical

2010
Development of liposomal salbutamol sulfate dry powder inhaler formulation.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:3

    Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Lactose; Liposomes; Lubrication; Nebulizers and Vaporizers; Particle Size; Phospholipids; Powders; Stearic Acids

2010
Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid.
    Die Pharmazie, 2010, Volume: 65, Issue:2

    Topics: Calorimetry, Differential Scanning; Drug Compounding; Excipients; Hardness Tests; Hypoglycemic Agents; Hypromellose Derivatives; Kinetics; Lactose; Metformin; Methylcellulose; Powders; Regression Analysis; Solubility; Spectrophotometry, Ultraviolet; Stearic Acids; Tablets

2010
Application of crustacean chitin as a co-diluent in direct compression of tablets.
    AAPS PharmSciTech, 2010, Volume: 11, Issue:1

    Topics: Cellulose; Chitin; Excipients; Lactose; Lubrication; Physical Phenomena; Powders; Pressure; Stearic Acids; Tablets

2010
Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend.
    International journal of pharmaceutics, 2010, Aug-16, Volume: 395, Issue:1-2

    Topics: Calibration; Cellulose; Chemistry, Pharmaceutical; Chlorpheniramine; Lactose; Least-Squares Analysis; Models, Statistical; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical

2010
In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process.
    International journal of pharmaceutics, 2010, Aug-30, Volume: 396, Issue:1-2

    Topics: Calibration; Cellulose; Chemistry, Pharmaceutical; Chlorpheniramine; Drug Compounding; Equipment Design; Excipients; Guidelines as Topic; Lactose; Least-Squares Analysis; Linear Models; Principal Component Analysis; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Spectroscopy, Near-Infrared; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical

2010
Scale-up model describing the impact of lubrication on tablet tensile strength.
    International journal of pharmaceutics, 2010, Oct-31, Volume: 399, Issue:1-2

    Topics: Calcium Phosphates; Cellulose; Drug Compounding; Lactose; Lubricants; Lubrication; Models, Chemical; Stearic Acids; Tablets; Tensile Strength

2010
An experimental investigation of the effect of the amount of lubricant on tablet properties.
    Drug development and industrial pharmacy, 2011, Volume: 37, Issue:2

    Topics: Cellulose; Excipients; Gamma Rays; Hardness; Lactose; Lubricants; Sodium Dodecyl Sulfate; Stearic Acids; Tablets; Technology, Pharmaceutical; Time Factors

2011
Mixing order of glidant and lubricant--influence on powder and tablet properties.
    International journal of pharmaceutics, 2011, May-16, Volume: 409, Issue:1-2

    Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Excipients; Hardness; Hydrophobic and Hydrophilic Interactions; Lactose; Lubricants; Powders; Silicon Dioxide; Solubility; Stearic Acids; Tablets

2011
Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation.
    Applied spectroscopy, 2011, Volume: 65, Issue:4

    Topics: Chemical Phenomena; Lactose; Lubrication; Pressure; Spectrophotometry, Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical

2011
Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging.
    International journal of pharmaceutics, 2011, Jun-15, Volume: 411, Issue:1-2

    Topics: Anti-Anxiety Agents; Cellulose; Computer Simulation; Excipients; Lactose; Lorazepam; Materials Testing; Pharmaceutical Preparations; Spectroscopy, Near-Infrared; Starch; Stearic Acids; Surface Properties; Tablets

2011
Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:8

    Topics: Lactose; Lubricants; Lubrication; Pharmaceutic Aids; Pharmaceutical Preparations; Photoelectron Spectroscopy; Powders; Rheology; Spectrometry, Mass, Secondary Ion; Stearic Acids; Surface Properties; Technology, Pharmaceutical

2011
Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties.
    International journal of pharmaceutics, 2011, Jul-15, Volume: 413, Issue:1-2

    Topics: Coated Materials, Biocompatible; Drug Compounding; Drug Delivery Systems; Excipients; Lactose; Microscopy, Electron, Scanning; Particle Size; Photoelectron Spectroscopy; Powders; Spectrometry, Mass, Secondary Ion; Stearic Acids; Surface Properties

2011
Determination of the scale of segregation of low dose tablets using hyperspectral imaging.
    International journal of pharmaceutics, 2011, Jul-29, Volume: 414, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Compounding; Excipients; Lactose; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Tolmetin

2011
Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Jul-17, Volume: 43, Issue:4

    Topics: Chromatography, Gas; Excipients; Lactose; Powders; Stearic Acids; Surface Properties

2011
An investigation into the impact of magnesium stearate on powder feeding during roller compaction.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:1

    Topics: Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Lactose; Lubricants; Lubrication; Particle Size; Pharmaceutical Preparations; Powders; Stearic Acids; Tablets; Technology, Pharmaceutical

2012
Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system.
    Acta pharmaceutica (Zagreb, Croatia), 2011, Sep-01, Volume: 61, Issue:3

    Topics: Antimetabolites, Antineoplastic; Cellulose; Colon; Colorectal Neoplasms; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Excipients; Fluorouracil; Hardness; Humans; Hydrogen-Ion Concentration; Lactose; Pharmacokinetics; Polymethacrylic Acids; Polyvinyls; Pressure; Pyrrolidines; Solubility; Stearic Acids; Tablets; Tablets, Enteric-Coated; Talc

2011
Cone milling of compacted flakes: process parameter selection by adopting the minimal fines approach.
    International journal of pharmaceutics, 2012, Jan-17, Volume: 422, Issue:1-2

    Topics: Cellulose; Chemistry, Pharmaceutical; Lactose; Particle Size; Pharmaceutical Preparations; Powders; Stearic Acids; Technology, Pharmaceutical

2012
Instrumented roll technology for the design space development of roller compaction process.
    International journal of pharmaceutics, 2012, Apr-15, Volume: 426, Issue:1-2

    Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Colloids; Drug Compounding; Equipment Design; Excipients; Feasibility Studies; Friction; Lactose; Lubricants; Models, Chemical; Pharmaceutical Preparations; Porosity; Pressure; Silicon Dioxide; Stearic Acids; Stress, Mechanical; Technology, Pharmaceutical; Tensile Strength; Transducers, Pressure

2012
Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume.
    International journal of pharmaceutics, 2012, Jun-15, Volume: 429, Issue:1-2

    Topics: Calcium Phosphates; Cellulose; Drug Compounding; Equipment Design; Excipients; Lactose; Lubrication; Stearic Acids; Tablets; Tensile Strength

2012
Decoupling the role of image size and calorie intake on gastric retention of swelling-based gastric retentive formulations: pre-screening in the dog model.
    International journal of pharmaceutics, 2012, Jul-15, Volume: 431, Issue:1-2

    Topics: Animals; Barium; Biological Availability; Cellulose; Delayed-Action Preparations; Diagnostic Imaging; Dogs; Drug Compounding; Energy Intake; Fasting; Food-Drug Interactions; Gastric Emptying; Hypromellose Derivatives; Lactose; Male; Metformin; Methylcellulose; Solubility; Stearic Acids

2012
Pulmonary delivery of dry powders to rats: tolerability limits of an intra-tracheal administration model.
    International journal of pharmaceutics, 2012, Sep-15, Volume: 434, Issue:1-2

    Topics: Animals; Drug Delivery Systems; Female; Insufflation; Lactose; Larynx; Lung; Powders; Rats; Rats, Sprague-Dawley; Stearic Acids; Trachea

2012
Influence of compaction properties and interfacial topography on the performance of bilayer tablets.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Cellulose; Excipients; Lactose; Stearic Acids; Stress, Mechanical; Surface Properties; Tablets; Technology, Pharmaceutical; Tensile Strength

2012
Prediction of the compressibility of complex mixtures of pharmaceutical powders.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Calcium Phosphates; Cellulose; Drug Compounding; Excipients; Lactose; Models, Theoretical; Particle Size; Povidone; Powders; Pressure; Stearic Acids

2012
Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:9

    Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chromatography, Gas; Drug Compounding; Drug Delivery Systems; Drug Storage; Dry Powder Inhalers; Excipients; Humans; Indomethacin; Lactose; Microscopy, Electron, Scanning; Osmolar Concentration; Particle Size; Powders; Solvents; Stearic Acids; Surface Properties

2012
Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets.
    AAPS PharmSciTech, 2012, Volume: 13, Issue:4

    Topics: Air; Cellulose; Crystallization; Drug Compounding; Drug Storage; Humidity; Lactose; Pressure; Stearic Acids; Tablets; Temperature; Tensile Strength

2012
Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Jan-23, Volume: 48, Issue:1-2

    Topics: Cellulose; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Lactose; Methylcellulose; Pharmaceutical Preparations; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Water

2013
In-line monitoring of the drug content of powder mixtures and tablets by near-infrared spectroscopy during the continuous direct compression tableting process.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Mar-12, Volume: 48, Issue:4-5

    Topics: Acetaminophen; Drug Compounding; Lactose; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Tablets

2013
Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics.
    AAPS PharmSciTech, 2013, Volume: 14, Issue:2

    Topics: Algorithms; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Computer Simulation; Lactose; Mannitol; Models, Chemical; Neural Networks, Computer; Papaverine; Pharmaceutical Preparations; Powders; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Tensile Strength

2013
Application of the combinative particle size reduction technology H 42 to produce fast dissolving glibenclamide tablets.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Jul-16, Volume: 49, Issue:4

    Topics: Chemistry, Pharmaceutical; Desiccation; Dioctyl Sulfosuccinic Acid; Glyburide; Hypoglycemic Agents; Lactose; Mannitol; Nanoparticles; Particle Size; Povidone; Pressure; Silicon Dioxide; Sodium Dodecyl Sulfate; Solubility; Stearic Acids; Tablets; Technology, Pharmaceutical

2013
Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets.
    International journal of pharmaceutics, 2013, Sep-15, Volume: 454, Issue:1

    Topics: Algorithms; Cellulose; Chemistry, Pharmaceutical; Elastic Modulus; Elasticity; Excipients; Lactose; Least-Squares Analysis; Lubricants; Models, Chemical; Molecular Structure; Particle Size; Scattering, Radiation; Starch; Stearic Acids; Stress, Mechanical; Tablets; Technology, Pharmaceutical; Transducers; Ultrasonics; Viscosity

2013
Investigations into the tensile failure of doubly-convex cylindrical tablets under diametral loading using finite element methodology.
    International journal of pharmaceutics, 2013, Sep-15, Volume: 454, Issue:1

    Topics: Chemistry, Pharmaceutical; Computer Simulation; Elasticity; Excipients; Finite Element Analysis; Glucose; Lactose; Linear Models; Models, Chemical; Polysaccharides, Bacterial; Stearic Acids; Stress, Mechanical; Tablets; Technology, Pharmaceutical; Tensile Strength

2013
Direct compression of cushion-layered ethyl cellulose-coated extended release pellets into rapidly disintegrating tablets without changes in the release profile.
    International journal of pharmaceutics, 2013, Dec-05, Volume: 457, Issue:2

    Topics: Carboxymethylcellulose Sodium; Cellulose; Delayed-Action Preparations; Drug Compounding; Excipients; Hardness; Lactose; Sorbitol; Stearic Acids; Tablets

2013
Effects of powder flow properties on capsule filling weight uniformity.
    Drug development and industrial pharmacy, 2013, Volume: 39, Issue:9

    Topics: Acetaminophen; Adhesiveness; Analgesics, Non-Narcotic; Capsules; Cellulose; Chemical Phenomena; Drug Compounding; Excipients; Lactose; Magnesium Silicates; Mechanical Phenomena; Particle Size; Powders; Quality Control; Rheology; Silicon Dioxide; Stearic Acids

2013
A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose.
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2013, Volume: 62, Issue:3

    Topics: Cellulose; Excipients; Lactose; Lubricants; Poloxamer; Stearic Acids; Tablets; Technology, Pharmaceutical; Tensile Strength

2013
Blending process modeling and control by multivariate curve resolution.
    Talanta, 2013, Dec-15, Volume: 117

    Topics: Acetaminophen; Algorithms; Calibration; Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Excipients; Humans; Lactose; Least-Squares Analysis; Multivariate Analysis; Reference Values; Spectrophotometry, Infrared; Stearic Acids

2013
Energy-based analysis of cone milling process for the comminution of roller compacted flakes.
    International journal of pharmaceutics, 2014, Feb-28, Volume: 462, Issue:1-2

    Topics: Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Lactose; Particle Size; Stearic Acids; Technology, Pharmaceutical

2014
A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:2

    Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Hardness; Ibuprofen; Lactose; Lubricants; Particle Size; Powders; Pressure; Solubility; Stearic Acids; Tablets; Theophylline

2014
The influence of polymorphism on the manufacturability and in vitro dissolution of sulindac-containing hard gelatin capsules.
    Pharmaceutical development and technology, 2015, Volume: 20, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chemistry, Pharmaceutical; Crystallization; Drug Liberation; Excipients; Gelatin; Lactose; Powders; Solubility; Stearic Acids; Sulindac

2015
Monitoring process induced attrition of drug substance particles within formulated blends.
    International journal of pharmaceutics, 2014, Aug-15, Volume: 470, Issue:1-2

    Topics: Cellulose; Drug Compounding; Excipients; Lactose; Microscopy, Electron, Scanning; Particle Size; Pharmaceutical Preparations; Stearic Acids

2014
Modeling strategies for pharmaceutical blend monitoring and end-point determination by near-infrared spectroscopy.
    International journal of pharmaceutics, 2014, Oct-01, Volume: 473, Issue:1-2

    Topics: Acetaminophen; Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Least-Squares Analysis; Models, Theoretical; Principal Component Analysis; Spectroscopy, Near-Infrared; Stearic Acids

2014
A method to evaluate the effect of contact with excipients on the surface crystallization of amorphous drugs.
    AAPS PharmSciTech, 2014, Volume: 15, Issue:6

    Topics: Cellulose; Chemistry, Pharmaceutical; Crystallization; Excipients; Humidity; Indomethacin; Kinetics; Lactose; Mannitol; Nifedipine; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Water

2014
Analysis of powder phenomena inside a Fette 3090 feed frame using in-line NIR spectroscopy.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 100

    Topics: Acetaminophen; Calibration; Equipment Design; Lactose; Models, Chemical; Particle Size; Powders; Reference Standards; Reproducibility of Results; Rheology; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical; Time Factors

2014
Commercial scale validation of a process scale-up model for lubricant blending of pharmaceutical powders.
    International journal of pharmaceutics, 2014, Nov-20, Volume: 475, Issue:1-2

    Topics: Algorithms; Calcium Phosphates; Cellulose; Chemical Phenomena; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Lactose; Lubricants; Lubrication; Mechanical Phenomena; Models, Chemical; Pharmaceutic Aids; Pharmaceutical Preparations; Quality Control; Reproducibility of Results; Stearic Acids; Tablets; Tensile Strength

2014
Milk production responses to dietary stearic acid vary by production level in dairy cattle.
    Journal of dairy science, 2015, Volume: 98, Issue:3

    Topics: Animals; Body Weight; Cattle; Diet; Dietary Fiber; Dietary Supplements; Digestion; Fats; Fatty Acids; Fatty Acids, Nonesterified; Female; Lactation; Lactose; Medicago sativa; Milk; Silage; Stearic Acids; Zea mays

2015
Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets.
    Pharmaceutical development and technology, 2016, Volume: 21, Issue:3

    Topics: Cellulose; Chemistry, Pharmaceutical; Excipients; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Lactose; Lubricants; Mannitol; Polyethylene Glycols; Povidone; Prednisone; Silicon Dioxide; Solubility; Stearic Acids; Tablets

2016
Tablet mechanics depend on nano and micro scale adhesion, lubrication and structure.
    International journal of pharmaceutics, 2015, Volume: 486, Issue:1-2

    Topics: Adhesiveness; Cellulose; Excipients; Hardness; Lactose; Lubrication; Mannitol; Powders; Stearic Acids; Tablets

2015
Strategy for design NIR calibration sets based on process spectrum and model space: An innovative approach for process analytical technology.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Calibration; Cellulose; Cetirizine; Chemistry, Pharmaceutical; Drug Industry; Excipients; Lactose; Least-Squares Analysis; Principal Component Analysis; Quality Control; Silicon Dioxide; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical

2015
In vitro and in vivo evaluations of buccal tablet formulations of ritodrine hydrochloride.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:6

    Topics: Administration, Buccal; Alginates; Animals; Cellulose; Chemistry, Pharmaceutical; Drug Liberation; Excipients; Glucuronic Acid; Hardness; Hexuronic Acids; Intestinal Absorption; Lactose; Male; Mouth; Rats, Wistar; Ritodrine; Solubility; Stearic Acids; Tablets

2015
Modern evaluation of liquisolid systems with varying amounts of liquid phase prepared using two different methods.
    BioMed research international, 2015, Volume: 2015

    Topics: Aluminum Compounds; Humans; Lactose; Magnesium Compounds; Polyethylene Glycols; Rosuvastatin Calcium; Silicates; Stearic Acids

2015
Investigation into process-induced de-aggregation of cohesive micronised API particles.
    International journal of pharmaceutics, 2015, Sep-30, Volume: 493, Issue:1-2

    Topics: Amidines; Cellulose; Lactose; Particle Size; Pyrazoles; Silicon Dioxide; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Stearic Acids; Technology, Pharmaceutical

2015
Setting local rank constraints by orthogonal projections for image resolution analysis: application to the determination of a low dose pharmaceutical compound.
    Analytica chimica acta, 2015, Sep-10, Volume: 892

    Topics: Cellulose; Indapamide; Lactose; Least-Squares Analysis; Models, Theoretical; Multivariate Analysis; Pharmaceutical Preparations; Principal Component Analysis; Spectrum Analysis, Raman; Stearic Acids; Tablets

2015
Dry Powder Coating using Planetary Centrifugal Mixer.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2015, Volume: 18, Issue:3

    Topics: Chemistry, Pharmaceutical; Excipients; Lactose; Particle Size; Powders; Stearic Acids; Surface Properties; X-Ray Diffraction

2015
Reevaluation of the diametral compression test for tablets using the flattened disc geometry.
    International journal of pharmaceutics, 2016, Nov-20, Volume: 513, Issue:1-2

    Topics: Calcium Phosphates; Finite Element Analysis; Lactose; Mannitol; Powders; Stearic Acids; Stress, Mechanical; Tablets; Technology, Pharmaceutical; Tensile Strength

2016
Influence of the Punch Head Design on the Physical Quality of Tablets Produced in a Rotary Press.
    Journal of pharmaceutical sciences, 2017, Volume: 106, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Compressive Strength; Drug Compounding; Equipment Design; Excipients; Lactose; Starch; Stearic Acids; Tablets; Tensile Strength

2017
Continuous monitoring of API content, API distribution and crushing strength after tableting via near-infrared chemical imaging.
    International journal of pharmaceutics, 2017, Feb-25, Volume: 518, Issue:1-2

    Topics: Caffeine; Drug Compounding; Hardness; Lactose; Least-Squares Analysis; Povidone; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical

2017
Application of Terahertz Attenuated Total Reflection Spectroscopy to Detect Changes in the Physical Properties of Lactose during the Lubrication Process Required for Drug Formulation.
    Chemical & pharmaceutical bulletin, 2017, Feb-01, Volume: 65, Issue:2

    Topics: Drug Compounding; Lactose; Lubrication; Pressure; Solubility; Stearic Acids; Tablets; Terahertz Spectroscopy; Time Factors

2017
Investigation into the Manufacture and Properties of Inhalable High-Dose Dry Powders Produced by Comilling API and Lactose with Magnesium Stearate.
    AAPS PharmSciTech, 2017, Volume: 18, Issue:6

    Topics: Administration, Inhalation; Aerosols; Dry Powder Inhalers; Lactose; Particle Size; Stearic Acids; Technology, Pharmaceutical

2017
Co-milled API-lactose systems for inhalation therapy: impact of magnesium stearate on physico-chemical stability and aerosolization performance.
    Drug development and industrial pharmacy, 2017, Volume: 43, Issue:6

    Topics: Administration, Inhalation; Adsorption; Aerosols; Drug Compounding; Drug Stability; Excipients; Humidity; Lactose; Particle Size; Powders; Respiratory Therapy; Stearic Acids

2017
Investigation of Spatial Heterogeneity of Salt Disproportionation in Tablets by Synchrotron X-ray Diffractometry.
    Molecular pharmaceutics, 2017, 04-03, Volume: 14, Issue:4

    Topics: Carboxymethylcellulose Sodium; Cellulose; Excipients; Humidity; Lactose; Pioglitazone; Stearic Acids; Synchrotrons; Tablets; Temperature; Thiazolidinediones; Water; X-Ray Diffraction

2017
Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, May-01, Volume: 102

    Topics: Cellulose; Lactose; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical

2017
The suitability of common compressibility equations for characterizing plasticity of diverse powders.
    International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1

    Topics: Algorithms; Calcium Phosphates; Celecoxib; Cellulose; Compressive Strength; Excipients; Hardness; Ibuprofen; Lactose; Mannitol; Powders; Stearic Acids

2017
Relationships between response surfaces for tablet characteristics of placebo and API-containing tablets manufactured by direct compression method.
    International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1

    Topics: Acetaminophen; Cellulose; Drug Compounding; Drug Design; Excipients; Lactose; Niacin; Placebos; Pressure; Pyridoxine; Salicylamides; Starch; Stearic Acids; Tablets

2017
Differences in Powder Properties of Two 1,4-Dihydropyridine-Type Compounds Evaluated through Thermal Analysis.
    Chemical & pharmaceutical bulletin, 2017, Volume: 65, Issue:12

    Topics: Calorimetry, Differential Scanning; Compressive Strength; Dihydropyridines; Lactose; Nifedipine; Nitrobenzenes; Piperazines; Stearic Acids; Tablets; Temperature

2017
Investigations on the Mechanism of Magnesium Stearate to Modify Aerosol Performance in Dry Powder Inhaled Formulations.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:4

    Topics: Administration, Inhalation; Aerosols; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Excipients; Lactose; Particle Size; Powders; Stearic Acids; Surface Properties

2018
A drop penetration method to measure powder blend wettability.
    International journal of pharmaceutics, 2018, Mar-01, Volume: 538, Issue:1-2

    Topics: Acetaminophen; Chemistry, Pharmaceutical; Dimethylpolysiloxanes; Excipients; Hydrophobic and Hydrophilic Interactions; Lactose; Lubricants; Powders; Stearic Acids; Surface Properties; Tablets; Water; Wettability

2018
Modeling the effects of material properties on tablet compaction: A building block for controlling both batch and continuous pharmaceutical manufacturing processes.
    International journal of pharmaceutics, 2018, May-30, Volume: 543, Issue:1-2

    Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Models, Theoretical; Stearic Acids; Tablets; Tensile Strength

2018
A mechanistic study on tablet ejection force and its sensitivity to lubrication for pharmaceutical powders.
    International journal of pharmaceutics, 2018, May-30, Volume: 543, Issue:1-2

    Topics: Calcium Phosphates; Drug Compounding; Excipients; Lactose; Lubrication; Mannitol; Mechanical Phenomena; Powders; Starch; Stearic Acids; Tablets

2018
Limitations of high dose carrier based formulations.
    International journal of pharmaceutics, 2018, Jun-10, Volume: 544, Issue:1

    Topics: Aerosols; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Beclomethasone; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Excipients; Glucocorticoids; Lactose; Microscopy, Electron, Scanning; Particle Size; Stearic Acids

2018
Determining the Influence of Granule Size on Simulation Parameters and Residual Shear Stress Distribution in Tablets by Combining the Finite Element Method into the Design of Experiments.
    Chemical & pharmaceutical bulletin, 2018, Volume: 66, Issue:5

    Topics: Finite Element Analysis; Lactose; Molecular Dynamics Simulation; Particle Size; Stearic Acids; Surface Properties; Tablets

2018
Rapid automated process development of a continuous capsule-filling process.
    International journal of pharmaceutics, 2018, Jul-30, Volume: 546, Issue:1-2

    Topics: Ascorbic Acid; Capsules; Drug Compounding; Lactose; Stearic Acids

2018
Deformation behavior of crystallized mannitol during compression using a rotary tablet press simulator.
    International journal of pharmaceutics, 2018, Aug-25, Volume: 547, Issue:1-2

    Topics: Cellulose; Compressive Strength; Crystallization; Lactose; Mannitol; Models, Theoretical; Particle Size; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical

2018
Towards quantitative prediction of the performance of dry powder inhalers by multi-scale simulations and experiments.
    International journal of pharmaceutics, 2018, Aug-25, Volume: 547, Issue:1-2

    Topics: Aerosols; Budesonide; Computer Simulation; Dry Powder Inhalers; Hydrodynamics; Lactose; Models, Theoretical; Particle Size; Stearic Acids

2018
Comparative evaluation of powder flow parameters with reference to particle size and shape.
    International journal of pharmaceutics, 2018, Aug-25, Volume: 547, Issue:1-2

    Topics: Excipients; Lactose; Metformin; Multivariate Analysis; Particle Size; Povidone; Powders; Rheology; Stearic Acids; Stress, Mechanical

2018
Understanding effects of process parameters and forced feeding on die filling.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Sep-15, Volume: 122

    Topics: Equipment Design; Excipients; Lactose; Particle Size; Powders; Rheology; Stearic Acids; Tablets; Technology, Pharmaceutical

2018
A systematic evaluation of dual functionality of sodium lauryl sulfate as a tablet lubricant and wetting enhancer.
    International journal of pharmaceutics, 2018, Dec-01, Volume: 552, Issue:1-2

    Topics: Celecoxib; Cellulose; Lactose; Lubricants; Sodium Dodecyl Sulfate; Stearic Acids; Surface-Active Agents; Tablets; Wettability

2018
Influence of moisture variation on the performance of Raman spectroscopy in quantitative pharmaceutical analyses.
    Journal of pharmaceutical and biomedical analysis, 2019, Feb-05, Volume: 164

    Topics: Acetaminophen; Administration, Oral; Calibration; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Humidity; Lactose; Models, Chemical; Spectrum Analysis, Raman; Stearic Acids

2019
Evaluation of an in-line NIR spectroscopic method for the determination of the residence time in a tablet press.
    International journal of pharmaceutics, 2019, Jun-30, Volume: 565

    Topics: Excipients; Lactose; Saccharin; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical; Time Factors

2019
Rapid Characterization of Formulated Pharmaceuticals Using Fast MAS
    Molecular pharmaceutics, 2019, 07-01, Volume: 16, Issue:7

    Topics: Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Cellulose; Drug Compounding; Excipients; Feasibility Studies; Hydrogen; Lactose; Mexiletine; Stearic Acids; Tablets; Theophylline; X-Ray Diffraction

2019
Effect of coating time on inter- and intra-tablet coating uniformity.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Sep-01, Volume: 137

    Topics: Cellulose; Drug Compounding; Excipients; Lactose; Polyvinyls; Stearic Acids; Tablets; Time Factors; Titanium; X-Ray Microtomography

2019
Assessing Particle Segregation Using Near-Infrared Chemical Imaging in Twin Screw Granulation.
    International journal of pharmaceutics, 2019, Sep-10, Volume: 568

    Topics: Lactose; Particle Size; Powders; Stearic Acids; Technology, Pharmaceutical

2019
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach.
    Drug development and industrial pharmacy, 2019, Volume: 45, Issue:10

    Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Cyproheptadine; Drug Compounding; Excipients; Fumarates; Lactose; Solubility; Starch; Stearic Acids; Tablets; Technology, Pharmaceutical

2019
Parameter estimation for roller compaction process using an instrumented vector TF mini roller compactor.
    Pharmaceutical development and technology, 2019, Volume: 24, Issue:10

    Topics: Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Lactose; Models, Statistical; Placebos; Powders; Pressure; Silicon Dioxide; Stearic Acids

2019
High Resolution Nanoscale Probing of Bacteriophages in an Inhalable Dry Powder Formulation for Pulmonary Infections.
    Analytical chemistry, 2019, 10-15, Volume: 91, Issue:20

    Topics: Bacteriophages; Desiccation; Humans; Lactose; Microscopy, Atomic Force; Powders; Respiratory Tract Infections; Spectroscopy, Fourier Transform Infrared; Stearic Acids; Viral Proteins

2019
Understanding the impact of magnesium stearate variability on tableting performance using a multivariate modeling approach.
    Pharmaceutical development and technology, 2020, Volume: 25, Issue:1

    Topics: Chemistry, Pharmaceutical; Excipients; Lactose; Lubricants; Lubrication; Particle Size; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Stearic Acids; Tablets

2020
Numerical study for tableting process in consideration of compression speed.
    International journal of pharmaceutics, 2020, Feb-15, Volume: 575

    Topics: Acetaminophen; Cellulose; Computer Simulation; Excipients; Lactose; Models, Theoretical; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical

2020
Investigation of the effects of particle size on fragmentation during tableting.
    International journal of pharmaceutics, 2020, Feb-25, Volume: 576

    Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Particle Size; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical; Tensile Strength

2020
A systematic evaluation of poloxamers as tablet lubricants.
    International journal of pharmaceutics, 2020, Feb-25, Volume: 576

    Topics: Administration, Oral; Cellulose; Drug Compounding; Drug Liberation; Excipients; Kinetics; Lactose; Lubricants; Poloxamer; Ritonavir; Solubility; Stearic Acids; Tablets

2020
Real-time quantification of low-dose cohesive formulations within a sampling interface for flowing powders.
    International journal of pharmaceutics, 2020, Oct-15, Volume: 588

    Topics: Cellulose; Drug Compounding; Excipients; Ibuprofen; Lactose; Particle Size; Powders; Quality Control; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical

2020
Evaluation of Weight Variation in Mini-Tablets Manufactured by a Multiple-Tip Tool.
    Chemical & pharmaceutical bulletin, 2020, Volume: 68, Issue:10

    Topics: Cellulose; Drug Compounding; Excipients; Lactose; Mannitol; Particle Size; Pressure; Starch; Stearic Acids; Surface Properties; Tablets

2020
Comprehensive Insight into Chemical Stability of Important Antidiabetic Drug Vildagliptin Using Chromatography (LC-UV and UHPLC-DAD-MS) and Spectroscopy (Mid-IR and NIR with PCA).
    Molecules (Basel, Switzerland), 2021, Sep-16, Volume: 26, Issue:18

    Topics: Chromatography, Liquid; Dipeptidyl-Peptidase IV Inhibitors; Drug Stability; Excipients; Hot Temperature; Humidity; Hydrogen-Ion Concentration; Hypoglycemic Agents; Kinetics; Lactose; Mannitol; Mass Spectrometry; Oxidation-Reduction; Povidone; Principal Component Analysis; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stearic Acids; Vildagliptin

2021
Exploring the influence of magnesium stearate content and mixing modality on the rheological properties and in vitro aerosolization of dry powder inhaler.
    International journal of pharmaceutics, 2023, Jul-25, Volume: 642

    Topics: Administration, Inhalation; Aerosols; Drug Carriers; Dry Powder Inhalers; Fluticasone; Lactose; Particle Size; Powders

2023
Impact of high shear blending on distribution of magnesium stearate on lactose for dry powder inhaled formulations.
    International journal of pharmaceutics, 2023, Nov-25, Volume: 647

    Topics: Administration, Inhalation; Dry Powder Inhalers; Excipients; Gas Chromatography-Mass Spectrometry; Lactose; Particle Size; Powders

2023