lactose has been researched along with stearic acid in 139 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.88) | 18.7374 |
| 1990's | 11 (7.91) | 18.2507 |
| 2000's | 28 (20.14) | 29.6817 |
| 2010's | 87 (62.59) | 24.3611 |
| 2020's | 9 (6.47) | 2.80 |
| Authors | Studies |
|---|---|
| Augsburger, LL; Marshall, K; Shah, KB | 1 |
| Bolhuis, GK; Lerk, CF; Smallenbroek, AJ | 1 |
| Ghaly, ES; Malavé, MI; Martí, A; Rivera, WJ | 1 |
| Armstrong, NA; Barnett, MI; Britten, JR | 1 |
| Drennen, JK; Wargo, DJ | 1 |
| Flachowsky, G; Lebzien, P; Möckel, P; Wagner, K | 1 |
| Bertoni, M; Bolhuis, GK; Bonferoni, CM; Caramella, C; Ferrari, F; Rossi, S | 1 |
| Eliasen, H; Kristensen, HG; Schaefer, T | 2 |
| Ghaly, ES; Vargas, CI | 1 |
| Badiello, R; Ceschel, GC; Maffei, P | 1 |
| Vashchuk, VV | 1 |
| Franceschinis, E; Moneghini, M; Perissutti, B; Voinovich, D | 1 |
| Matsuda, Y; Otsuka, M; Sato, M | 1 |
| Arratia, P; Duong, NH; Lange, A; Muzzio, F; Reynolds, S; Timmermans, J | 1 |
| Mraz, FR; Waibel, PE | 1 |
| Tove, SB | 1 |
| Filipovic-Grcic, J; Franceschinis, E; Grassi, M; Perissutti, B; Voinovich, D | 1 |
| Bowtell, RW; Köckenberger, W; MacRae, RJ; Melia, CD; Ross, AC; Stevens, HN; Sutch, JC | 1 |
| Lovato, D; Marchitto, L; Martelli, S; Palmieri, GF; Zanchetta, A | 1 |
| Muzíková, J; Páleník, L | 1 |
| Jiang, RG; Liu, H; Pan, WS; Wang, CL; Wang, LQ; Zhang, PW | 1 |
| Gray, A; Hasenzahl, S; Jonat, S; Schmidt, PC | 1 |
| Lee, J | 2 |
| Jahn, T; Steffens, KJ | 1 |
| Cobb, J; Saracovan, I; Swaminathan, V | 1 |
| Corrigan, OI; Killen, BU | 1 |
| Otsuka, M; Yamane, I | 1 |
| Bunker, MJ; Davies, MC; James, MB; Roberts, CJ | 1 |
| Ando, M; Kojima, S; Nabeshima, T; Nakayama, Y; Ozeki, Y | 1 |
| Faqih, A; Levin, M; Llusa, M; Mehrotra, A; Muzzio, FJ | 1 |
| Faqih, AM; Hammond, SV; Mehrotra, A; Muzzio, FJ | 1 |
| Davies, PN; Newton, JM; Podczeck, F; Worthington, HE | 1 |
| Ando, M; Nakayama, Y; Shimizu, K | 1 |
| Heilweil, EJ; Hussain, AS; Khan, MA; Wu, H | 1 |
| Frei, M; Guchardi, R; John, E; Kaerger, JS | 1 |
| Kojima, M; Kuno, Y; Nakagami, H; Terada, K; Yonemochi, E | 1 |
| Kumon, M; Kusai, A; Machida, S; Suzuki, M; Terada, K; Yonemochi, E | 1 |
| Alvarez-Nunez, FA; Chang, CK; Magnusson, LE; Rinella, JV; Sueda, K | 1 |
| Badillo, N; Ghaly, ES | 1 |
| Irisawa, Y; Okimoto, K; Okuda, Y; Osawa, T; Yamashita, S | 1 |
| Armstrong, B; Larson, I; Morton, DA; Stewart, PJ; Zhou, Q | 1 |
| Bariya, SH; Gohel, M | 1 |
| Heng, PW; Karande, AD; Liew, CV | 3 |
| Huang, WH; Liu, L; Wong, YF; Wu, H; Yang, ZJ; Zhao, ZZ | 1 |
| Dittgen, M; Jouma, M; Neubert, RH; Rajab, M | 1 |
| Antikainen, O; Colarte, AI; Heinämäki, J; Mir, VG; Nieto, OM; Revoredo, OB; Sandler, N; Yliruusi, J | 1 |
| Kushner, J; Moore, F | 1 |
| Bertrand, F; Chaouki, J; Perrault, M | 1 |
| Cuitino, A; Lewis, D; Mendez, R; Michniak-Kohn, B; Muzzio, F; Pingali, K | 1 |
| Colón, Y; Johnson-Restrepo, B; Romañach, RJ; Ropero, J | 1 |
| Amigo, JM; Coello, J; Franch-Lage, F; Maspoch, S; Skibsted, E | 1 |
| Das, S; Denman, JA; Gengenbach, T; Larson, I; Morton, DAV; Qu, L; Stewart, PJ; Zhang, H; Zhou, QT | 1 |
| Denman, JA; Gengenbach, T; Larson, I; Morton, DA; Qu, L; Stewart, PJ; Zhou, QT | 1 |
| Carvajal, MT; Ely, DR | 1 |
| Das, SC; Larson, I; Morton, DA; Stewart, PJ; Zhou, Q | 1 |
| Dawes, J; Gamble, JF; Greenwood, R; Robbins, P; Tobyn, M | 1 |
| Kumar, RV; Sinha, VR | 1 |
| Heng, PW; Ng, KY; Samanta, AK | 1 |
| Early, W; Gao, Z; Jerzewski, R; Levin, M; Miller, R; Nesarikar, VV; Pandey, P; Patel, C; Sprockel, O; Vatsaraj, N | 1 |
| Kushner, J | 1 |
| Elkes, R; Jin, L; Lalloo, AK; McConnell, EL; Seiler, C; Wu, Y | 1 |
| de Monte, M; Diot, P; Guillemain, J; Guillon, A; Montharu, J; Roseau, G; Schubnel, V; Vecellio, L | 1 |
| Abebe, A; Akseli, I; Cuitiño, AM; Kottala, N; Nikfar, F; Sprockel, O | 1 |
| Busignies, V; Diarra, H; Mazel, V; Tchoreloff, P | 1 |
| Das, SC; Stewart, PJ | 1 |
| Abebe, A; Bergum, J; Cuitiño, AM; Kottala, N; Nikfar, F; Sprockel, O | 1 |
| Aher, AA; Desai, SS; Kadaskar, PT | 1 |
| Avalle, P; Jastrzemska, A; Pritchard, J; Pygall, SR | 1 |
| Borchert, S; Hoehe, W; Järvinen, K; Järvinen, M; Juuti, M; Poutiainen, S | 1 |
| Ilič, I; Kása, P; Papós, K; Pintye-Hódi, K; Sovány, T; Srčič, S | 1 |
| Möschwitzer, JP; Müller, RH; Salazar, J | 1 |
| Cetinkaya, C; Hancock, BC; Krishna Prasad Vallabh, C; Saeedi Vahdat, A | 1 |
| Drake, KR; Newton, JM; Podczeck, F | 1 |
| Bodmeier, R; Hosseini, A; Körber, M | 1 |
| Muzzio, FJ; Osorio, JG | 1 |
| Mužíková, J; Sináglová, P | 1 |
| Anderson, CA; de Juan, A; Drennen, JK; Igne, B; Jaumot, J | 1 |
| Heng, PW; Ng, KY; Samanta, AK; Wang, L | 1 |
| Agarwal, K; Hicks, I; Kane, A; Kathiria, L; Kushner, J; Langdon, BA; Li, F; Ranade, G; Song, D | 1 |
| Guadalupe Sánchez-González, E; Jesús Hernández-Abad, V; Jung Cook, H; Yépez-Mulia, L | 1 |
| Gamble, JF; Hoffmann, M; Hughes, H; Hutchins, P; Tobyn, M | 1 |
| Anderson, CA; de Juan, A; Drennen, JK; Igne, B; Jaumot, J; Lallemand, J; Preys, S | 1 |
| de Villiers, MM; Derdour, L; Huang, J; Hussain, MA; Qian, F; Yu, L; Zhang, SW | 1 |
| Colon, Y; Mateo-Ortiz, D; Méndez, R; Romañach, RJ | 1 |
| Kushner, J; Schlack, H | 1 |
| Allen, MS; Lock, AL; Piantoni, P | 1 |
| Mashru, R; Mittal, K; Patadia, R; Vora, C | 1 |
| Badal Tejedor, M; Millqvist-Fureby, A; Nordgren, N; Rutland, MW; Schuleit, M | 1 |
| Alcalà, M; Blanco, M; Cárdenas, V; Cordobés, M | 1 |
| Onishi, H; Sakata, O; Yumoto, K | 1 |
| Gajdziok, J; Vetchý, D; Vraníková, B | 1 |
| Gamble, JF; Hoffmann, M; Tobyn, M; Wray, PS | 1 |
| Boiret, M; de Juan, A; Ginot, YM; Gorretta, N; Roger, JM | 1 |
| Kagawa, Y; Miyawaki, K; Miyazaki, Y; Uchino, T | 1 |
| Edge, S; Lewis, D; Price, R; Shur, J; Singh, D; Woollam, G; Young, PM | 1 |
| Busignies, V; Croquelois, B; Diarra, H; Girardot, J; Guerard, S; Kopp, JB; Mazel, V; Tchoreloff, P | 1 |
| Anbalagan, P; Heng, PWS; Liew, CV; Sarkar, S | 1 |
| Kerschhaggl, M; Khinast, JG; Pucher, I; Sacher, S; Scheibelhofer, O; Wahl, PR | 1 |
| Dohi, M; Hakomori, T; Momose, W; Noguchi, S; Sato, S; Terada, K; Yamashita, K | 1 |
| Lau, M; Traini, D; Young, PM | 2 |
| Govindarajan, R; Koranne, S; Suryanarayanan, R | 1 |
| Crean, AM; Crowley, ME; Hayes, K; Hegarty, A; Kiernan, L; McAuliffe, MAP; O'Mahony, GE | 1 |
| Paul, S; Sun, CC | 1 |
| Hayashi, Y; Hirai, D; Kosugi, A; Kumada, S; Oishi, T; Onuki, Y; Shirotori, K; Takayama, K; Tsuji, T | 1 |
| Hosaka, S; Tokunaga, Y | 1 |
| Imanidis, G; Jetzer, MW; Morrical, BD; Schneider, M | 1 |
| Callegari, G; Drazer, G; Liu, Z; Muzzio, F; Wang, Y | 1 |
| Escotet-Espinoza, MS; Ierapetritou, MG; Muzzio, FJ; Singh, R; Vadodaria, S | 1 |
| Leung, LY; Mao, C; Uzondu, B; Yang, CY | 1 |
| Church, T; Lewis, D; Traini, D; Tweedie, A; Yeung, S; Young, PM | 1 |
| Hayashi, Y; Kosugi, A; Miura, T; Onuki, Y; Takayama, K | 1 |
| Brinz, T; Khinast, J; Otterbach, S; Wagner, B | 1 |
| Aubert, A; Bataille, B; Baylac, G; Lefevre, P; Sanchez-Ballester, N; Sharkawi, T; Soulairol, I; Tarlier, N | 1 |
| Björn, IN; Nguyen, D; Remmelgas, J; Thalberg, K; van Wachem, B | 1 |
| Goh, HP; Heng, PWS; Liew, CV | 2 |
| Boulas, P; Dun, J; Lin, Y; Osei-Yeboah, F; Sun, CC | 2 |
| Anderson, CA; Drennen, JK; Hossain, MN; Igne, B | 1 |
| De Beer, T; De Leersnyder, F; Kumar, A; Vanhoorne, V; Vervaet, C | 1 |
| Carnahan, SL; Hirsh, DA; Hung, I; Lubach, JW; Nagapudi, K; Rossini, AJ; Wijesekara, AV | 1 |
| Kleinebudde, P; Radtke, J; Wiedey, R | 1 |
| Cartwright, JJ; Mundozah, AL; Omar, CS; Salman, AD; Tridon, CC; Yang, J | 1 |
| Baltodano Viales, E; Calvo Guzmán, B; Carazo Berrocal, G; Castillo Henríquez, L; Madrigal Redondo, G; Vargas Zúñiga, R | 1 |
| Nesarikar, V; Phanse, R; Reddy, JP | 1 |
| Chan, HK; Chang, RYK; Chrzanowski, W; Khanal, D; Morales, S | 1 |
| Hoag, SW; Ibrahim, A; Wang, T | 1 |
| Kushida, K; Matsuda, Y; Nakamura, H; Ohsaki, S; Watano, S | 1 |
| Rantanen, J; Skelbæk-Pedersen, AL; Vilhelmsen, TK; Wallaert, V | 1 |
| Méndez, R; Romañach, RJ; Sierra-Vega, NO | 1 |
| Kashiwagura, Y; Kurashima, H; Namiki, N; Tanaka, S; Uchida, S | 1 |
| Berecka-Rycerz, A; Fornal, E; Granica, S; Gumieniczek, A; Żyżyńska-Granica, B | 1 |
| Guan, J; He, X; Li, J; Ma, S; Mao, S; Sun, Y; Zhang, X | 1 |
| Imole, O; Marek, K; Mehta, M; Peters, H; van der Wel, P; Welle, A | 1 |
2 review(s) available for lactose and stearic acid
| Article | Year |
|---|---|
Methods for reduction of cohesive forces between carrier and drug in DPI formulation.
Topics: Adhesiveness; Administration, Inhalation; Chemical Phenomena; Drug Carriers; Drug Compounding; Drug Stability; Dry Powder Inhalers; Excipients; Humans; Lactose; Lung; Polyethylene Glycols; Powders; Respiratory System Agents; Stearic Acids; Tissue Distribution | 2013 |
From single excipients to dual excipient platforms in dry powder inhaler products.
Topics: Administration, Inhalation; Drug Compounding; Dry Powder Inhalers; Excipients; Humans; Lactose; Particle Size; Respiratory Therapy; Stearic Acids; Surface Properties | 2016 |
1 trial(s) available for lactose and stearic acid
| Article | Year |
|---|---|
[The use of the catalase P-47 preparation for treating long-term nonhealing wounds and trophic ulcers].
Topics: Aged; Catalase; Chronic Disease; Drug Combinations; Hexachlorophene; Humans; Lactose; Middle Aged; Stearic Acids; Time Factors; Ulcer; Wound Healing | 1993 |
136 other study(ies) available for lactose and stearic acid
| Article | Year |
|---|---|
An investigation of some factors influencing plug formation and fill weight in a dosing disk-type automatic capsule-filling machine.
Topics: Capsules; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Stearic Acids; Technology, Pharmaceutical | 1986 |
Interaction of tablet disintegrants and magnesium stearate during mixing I: Effect on tablet disintegration.
Topics: Aspirin; Calcium Phosphates; Drug Compounding; Excipients; Hardness; Lactose; Solubility; Starch; Stearic Acids; Tablets | 1981 |
Controlled release of theophylline from inert matrices: effect of channeling material on release rate.
Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Delivery Systems; Drug Design; Lactose; Stearic Acids; Tablets; Theophylline; Time Factors | 1993 |
Studies on powder plug formation using a simulated capsule filling machine.
Topics: Drug Compounding; Lactose; Starch; Stearic Acids; Tablets | 1996 |
Near-infrared spectroscopic characterization of pharmaceutical powder blends.
Topics: Carboxymethylcellulose Sodium; Hydrochlorothiazide; Lactose; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical; Time Factors | 1996 |
Influence of duodenal infusion of nicotinic acid on the milk fat composition of dairy cows.
Topics: Administration, Oral; Animals; Catheterization; Cattle; Chromatography, Gas; Dose-Response Relationship, Drug; Duodenum; Fatty Acids; Female; Intestinal Absorption; Lactose; Lipid Metabolism; Lipids; Milk; Niacin; Niacinamide; Oleic Acid; Proteins; Stearic Acids | 1997 |
Dissolution enhancement of an insoluble drug by physical mixture with a superdisintegrant: optimization with a simplex lattice design.
Topics: Anti-Inflammatory Agents; Calcium Phosphates; Carboxymethylcellulose Sodium; Excipients; Hardness Tests; Kinetics; Lactose; Prednisone; Regression Analysis; Solubility; Stearic Acids; Tablets | 1996 |
Electrostatic charging during a melt agglomeration process.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Excipients; Glycerides; Humidity; Lactose; Polyethylene Glycols; Static Electricity; Stearic Acids; Viscosity | 1999 |
Growth mechanisms in melt agglomeration with a low viscosity binder.
Topics: Chemistry, Pharmaceutical; Image Processing, Computer-Assisted; Lactose; Microscopy, Electron, Scanning; Particle Size; Porosity; Stearic Acids; Temperature; Viscosity; Water | 1999 |
Kinetic release of theophylline from hydrophilic swellable matrices.
Topics: Administration, Oral; Excipients; Lactose; Methylcellulose; Models, Theoretical; Oxazines; Polymers; Solubility; Solvents; Stearic Acids; Tablets; Theophylline; Time Factors | 1999 |
Optimization of a tablet containing chlorthalidone.
Topics: Algorithms; Antihypertensive Agents; Cellulose; Chlorthalidone; Excipients; Hardness Tests; Lactose; Models, Theoretical; Pressure; Stearic Acids; Tablets | 1999 |
Melt pelletization in high shear mixer using a hydrophobic melt binder: influence of some apparatus and process variables.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Hydrophobic and Hydrophilic Interactions; Lactose; Stearic Acids; Tablets; Technology, Pharmaceutical | 2001 |
Comparative evaluation of tableting compression behaviors by methods of internal and external lubricant addition: inhibition of enzymatic activity of trypsin preparation by using external lubricant addition during the tableting compression process.
Topics: Algorithms; Cellulose; Excipients; Hardness; Lactose; Lubrication; Solutions; Stearic Acids; Tablets; Technology, Pharmaceutical; Trypsin | 2001 |
A homogeneity study using NIR spectroscopy: tracking magnesium stearate in Bohle bin-blender.
Topics: Cellulose; Excipients; Lactose; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical | 2003 |
CALCIUM, STRONTIUM AND PHOSPHORUS UTILIZATION BY CHICKS AS INFLUENCED BY NUTRITIONAL AND ENDOCRINE VARIATIONS.
Topics: Alkaline Phosphatase; Animals; Blood; Calcium; Calcium, Dietary; Chickens; Diet; Estradiol; Glucose; Hydrocortisone; Lactose; Pharmacology; Phosphorus; Poultry; Research; Sorbitol; Stearic Acids; Strontium; Testosterone; Vitamin D; Vitamins | 1964 |
TOXICITY OF SATURATED FAT.
Topics: Carbohydrates; Cholesterol; Dietary Fats; Fatty Acids; Lactose; Mice; Palmitic Acid; Pharmacology; Research; Stearic Acids; Toxicology | 1964 |
Theoretical and experimental study on theophylline release from stearic acid cylindrical delivery systems.
Topics: Algorithms; Computer Simulation; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Electron Probe Microanalysis; Kinetics; Lactose; Models, Theoretical; Polyethylene Glycols; Pressure; Solubility; Spectrophotometry, Ultraviolet; Stearic Acids; Theophylline | 2003 |
Investigating the coating-dependent release mechanism of a pulsatile capsule using NMR microscopy.
Topics: Calcium Phosphates; Capsules; Carboxymethylcellulose Sodium; Cellulose; Delayed-Action Preparations; Drug Delivery Systems; Excipients; Image Processing, Computer-Assisted; Kinetics; Lactose; Magnetic Resonance Imaging; Propranolol; Solvents; Spectrophotometry, Ultraviolet; Stearic Acids; Water | 2003 |
Evaluation of the mixing effectiveness of a new powder mixer.
Topics: Cellulose; Drug Compounding; Excipients; Hardness; Lactose; Microscopy, Electron, Scanning; Powders; Quality Control; Salicylic Acid; Stearic Acids; Time Factors | 1998 |
[A study of the properties of compacts from a mixed dry binder on the base of alpha-lactose monohydrate and microcrystalline cellulose].
Topics: Cellulose; Compressive Strength; Lactose; Pharmaceutic Aids; Stearic Acids; Tablets; Tensile Strength | 2005 |
[Effect of surface modification on surface energy of lactose and performance of dry powder inhalations].
Topics: Administration, Inhalation; Chromatography, Gas; Drug Carriers; Interferon alpha-2; Interferon-alpha; Lactose; Particle Size; Powders; Recombinant Proteins; Stearic Acids; Surface Properties; Talc; Technology, Pharmaceutical | 2005 |
Influence of compacted hydrophobic and hydrophilic colloidal silicon dioxide on tableting properties of pharmaceutical excipients.
Topics: Cellulose; Chemistry, Pharmaceutical; Colloids; Drug Compounding; Drug Stability; Excipients; Hydrophobic and Hydrophilic Interactions; Lactose; Silicon Dioxide; Starch; Stearic Acids; Tablets; Tensile Strength; Water | 2005 |
Intrinsic adhesion properties of poly(vinyl pyrrolidone) to pharmaceutical materials: humidity effect.
Topics: Adhesiveness; Humidity; Hydrophobic and Hydrophilic Interactions; Lactose; Pharmaceutic Aids; Povidone; Stearic Acids | 2005 |
Press chamber coating as external lubrication for high speed rotary presses: lubricant spray rate optimization.
Topics: Calibration; Drug Compounding; Equipment Design; Excipients; Lactose; Lubrication; Mannitol; Sorbitol; Spectrophotometry, Atomic; Starch; Stearic Acids; Tablets; Tensile Strength | 2005 |
Measurement of the surface energy of lubricated pharmaceutical powders by inverse gas chromatography.
Topics: Cellulose; Chromatography, Gas; Excipients; Lactose; Lubrication; Powders; Stearic Acids; Surface Properties | 2006 |
Effect of soluble filler on drug release from stearic acid based compacts.
Topics: Benzoic Acid; Drug Carriers; Drug Compounding; Drug Design; Insulin; Kinetics; Lactose; Solubility; Stearic Acids | 2006 |
Prediction of tablet hardness based on near infrared spectra of raw mixed powders by chemometrics.
Topics: Cellulose; Dipyrone; Drug Compounding; Excipients; Hardness; Lactose; Lubrication; Models, Chemical; Powders; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared; Starch; Stearic Acids; Tablets | 2006 |
A nanoscale study of particle friction in a pharmaceutical system.
Topics: Drug Combinations; Drug Stability; Friction; Lactose; Microscopy, Atomic Force; Nanotechnology; Particle Size; Pharmaceutical Preparations; Polytetrafluoroethylene; Stearic Acids; Surface Properties; Technology, Pharmaceutical; Zanamivir | 2006 |
Development and evaluation of a novel dry-coated tablet technology for pellets as a substitute for the conventional encapsulation technology.
Topics: Cellulose; Delayed-Action Preparations; Drug Compounding; Elasticity; Food Coloring Agents; Lactose; Particle Size; Pressure; Stearic Acids; Sulfonamides; Tablets, Enteric-Coated; Tamsulosin; Technology, Pharmaceutical; Tensile Strength | 2007 |
Influence of shear intensity and total shear on properties of blends and tablets of lactose and cellulose lubricated with magnesium stearate.
Topics: Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Hardness; Lactose; Lubrication; Powders; Rheology; Stearic Acids; Surface Properties; Tablets | 2007 |
Effect of moisture and magnesium stearate concentration on flow properties of cohesive granular materials.
Topics: Cellulose; Chemical Phenomena; Chemistry, Physical; Drug Stability; Excipients; Hardness; Humidity; Lactose; Lubrication; Powders; Rheology; Solubility; Stearic Acids; Surface Properties; Technology, Pharmaceutical | 2007 |
The determination of the mechanical strength of tablets of different shapes.
Topics: Cellulose; Drug Compounding; Excipients; Hardness; Hardness Tests; Lactose; Particle Size; Pressure; Stearic Acids; Tablets | 2007 |
Nanoscopic friction behavior of pharmaceutical materials.
Topics: Acetaminophen; Adhesiveness; Chemistry, Pharmaceutical; Dosage Forms; Drug Compounding; Excipients; Friction; Fumarates; Kinetics; Lactose; Microscopy, Atomic Force; Models, Chemical; Nanotechnology; Stainless Steel; Stearic Acids; Surface Properties; Technology, Pharmaceutical | 2007 |
Characterization of tableting using the OSDRC system.
Topics: Cellulose; Compressive Strength; Lactose; Phenacetin; Porosity; Powders; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical | 2007 |
Process analytical technology (PAT): effects of instrumental and compositional variables on terahertz spectral data quality to characterize pharmaceutical materials and tablets.
Topics: Cellulose; Excipients; Lactose; Pharmaceutical Preparations; Spectrum Analysis; Starch; Stearic Acids; Tablets; Technology, Pharmaceutical; Theophylline | 2007 |
Influence of fine lactose and magnesium stearate on low dose dry powder inhaler formulations.
Topics: Administration, Inhalation; Algorithms; Bronchodilator Agents; Drug Stability; Ethanolamines; Excipients; Formoterol Fumarate; Lactose; Light; Mechanics; Particle Size; Pharmaceutical Vehicles; Powders; Scattering, Radiation; Sonication; Stearic Acids | 2008 |
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.
Topics: Absorption; Administration, Oral; Chemical Phenomena; Chemistry, Physical; Excipients; Fumarates; Hardness; Lactose; Lubricants; Porosity; Solubility; Stearic Acids; Sugar Alcohols; Surface Properties; Tablets; Talc; Water; Xylitol | 2008 |
Application and mechanism of inhalation profile improvement of DPI formulations by mechanofusion with magnesium stearate.
Topics: Adhesiveness; Administration, Inhalation; Algorithms; Chemistry, Pharmaceutical; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Excipients; Lactose; Microscopy, Electron, Scanning; Powders; Spectrophotometry, Ultraviolet; Stearic Acids; Surface Properties | 2008 |
Roller compaction, granulation and capsule product dissolution of drug formulations containing a lactose or mannitol filler, starch, and talc.
Topics: Capsules; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Compounding; Drug Stability; Excipients; Gelatin; Humidity; Lactose; Mannitol; Models, Chemical; Particle Size; Powders; Rheology; Solubility; Starch; Stearic Acids; Talc; Technology, Pharmaceutical; Temperature; Tensile Strength; Time Factors | 2008 |
In vitro evaluation of theophylline matrices using xyloglucan.
Topics: Bronchodilator Agents; Buffers; Calcium Phosphates; Cellulose; Delayed-Action Preparations; Excipients; Glucans; Hydrochloric Acid; Lactose; Rotation; Stearic Acids; Theophylline; Water; Xylans | 2008 |
A new formulation for orally disintegrating tablets using a suspension spray-coating method.
Topics: Administration, Oral; Chemistry, Pharmaceutical; Excipients; Hardness; Kinetics; Lactose; Linear Models; Mannitol; Models, Chemical; Particle Size; Porosity; Povidone; Silicic Acid; Solubility; Starch; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Trehalose | 2009 |
Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating.
Topics: Algorithms; Chemistry, Pharmaceutical; Desiccation; Drug Compounding; Excipients; Lactose; Microscopy, Electron, Scanning; Particle Size; Powders; Rheology; Stearic Acids | 2010 |
Advanced formulation design of venlafaxine hydrochloride coated and triple-layer tablets containing hypromellose.
Topics: Algorithms; Antidepressive Agents, Second-Generation; Biological Availability; Cellulose; Chemistry, Pharmaceutical; Cyclohexanols; Delayed-Action Preparations; Drug Stability; Ethanol; Excipients; Hypromellose Derivatives; Lactose; Methylcellulose; Models, Chemical; Models, Statistical; Stearic Acids; Tablets, Enteric-Coated; Venlafaxine Hydrochloride; Water | 2009 |
In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy.
Topics: Calibration; Cellulose; Chemistry, Pharmaceutical; Chlorpheniramine; Equipment Design; Excipients; Lactose; Least-Squares Analysis; Particle Size; Powders; Reproducibility of Results; Spectroscopy, Near-Infrared; Stearic Acids; Surface Properties; Technology, Pharmaceutical | 2010 |
Development of liposomal salbutamol sulfate dry powder inhaler formulation.
Topics: Administration, Inhalation; Albuterol; Bronchodilator Agents; Chemistry, Pharmaceutical; Lactose; Liposomes; Lubrication; Nebulizers and Vaporizers; Particle Size; Phospholipids; Powders; Stearic Acids | 2010 |
Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid.
Topics: Calorimetry, Differential Scanning; Drug Compounding; Excipients; Hardness Tests; Hypoglycemic Agents; Hypromellose Derivatives; Kinetics; Lactose; Metformin; Methylcellulose; Powders; Regression Analysis; Solubility; Spectrophotometry, Ultraviolet; Stearic Acids; Tablets | 2010 |
Application of crustacean chitin as a co-diluent in direct compression of tablets.
Topics: Cellulose; Chitin; Excipients; Lactose; Lubrication; Physical Phenomena; Powders; Pressure; Stearic Acids; Tablets | 2010 |
Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend.
Topics: Calibration; Cellulose; Chemistry, Pharmaceutical; Chlorpheniramine; Lactose; Least-Squares Analysis; Models, Statistical; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical | 2010 |
In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process.
Topics: Calibration; Cellulose; Chemistry, Pharmaceutical; Chlorpheniramine; Drug Compounding; Equipment Design; Excipients; Guidelines as Topic; Lactose; Least-Squares Analysis; Linear Models; Principal Component Analysis; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Spectroscopy, Near-Infrared; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical | 2010 |
Scale-up model describing the impact of lubrication on tablet tensile strength.
Topics: Calcium Phosphates; Cellulose; Drug Compounding; Lactose; Lubricants; Lubrication; Models, Chemical; Stearic Acids; Tablets; Tensile Strength | 2010 |
An experimental investigation of the effect of the amount of lubricant on tablet properties.
Topics: Cellulose; Excipients; Gamma Rays; Hardness; Lactose; Lubricants; Sodium Dodecyl Sulfate; Stearic Acids; Tablets; Technology, Pharmaceutical; Time Factors | 2011 |
Mixing order of glidant and lubricant--influence on powder and tablet properties.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Excipients; Hardness; Hydrophobic and Hydrophilic Interactions; Lactose; Lubricants; Powders; Silicon Dioxide; Solubility; Stearic Acids; Tablets | 2011 |
Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation.
Topics: Chemical Phenomena; Lactose; Lubrication; Pressure; Spectrophotometry, Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical | 2011 |
Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging.
Topics: Anti-Anxiety Agents; Cellulose; Computer Simulation; Excipients; Lactose; Lorazepam; Materials Testing; Pharmaceutical Preparations; Spectroscopy, Near-Infrared; Starch; Stearic Acids; Surface Properties; Tablets | 2011 |
Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach.
Topics: Lactose; Lubricants; Lubrication; Pharmaceutic Aids; Pharmaceutical Preparations; Photoelectron Spectroscopy; Powders; Rheology; Spectrometry, Mass, Secondary Ion; Stearic Acids; Surface Properties; Technology, Pharmaceutical | 2011 |
Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties.
Topics: Coated Materials, Biocompatible; Drug Compounding; Drug Delivery Systems; Excipients; Lactose; Microscopy, Electron, Scanning; Particle Size; Photoelectron Spectroscopy; Powders; Spectrometry, Mass, Secondary Ion; Stearic Acids; Surface Properties | 2011 |
Determination of the scale of segregation of low dose tablets using hyperspectral imaging.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Compounding; Excipients; Lactose; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Tolmetin | 2011 |
Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate.
Topics: Chromatography, Gas; Excipients; Lactose; Powders; Stearic Acids; Surface Properties | 2011 |
An investigation into the impact of magnesium stearate on powder feeding during roller compaction.
Topics: Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Lactose; Lubricants; Lubrication; Particle Size; Pharmaceutical Preparations; Powders; Stearic Acids; Tablets; Technology, Pharmaceutical | 2012 |
Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system.
Topics: Antimetabolites, Antineoplastic; Cellulose; Colon; Colorectal Neoplasms; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Excipients; Fluorouracil; Hardness; Humans; Hydrogen-Ion Concentration; Lactose; Pharmacokinetics; Polymethacrylic Acids; Polyvinyls; Pressure; Pyrrolidines; Solubility; Stearic Acids; Tablets; Tablets, Enteric-Coated; Talc | 2011 |
Cone milling of compacted flakes: process parameter selection by adopting the minimal fines approach.
Topics: Cellulose; Chemistry, Pharmaceutical; Lactose; Particle Size; Pharmaceutical Preparations; Powders; Stearic Acids; Technology, Pharmaceutical | 2012 |
Instrumented roll technology for the design space development of roller compaction process.
Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Colloids; Drug Compounding; Equipment Design; Excipients; Feasibility Studies; Friction; Lactose; Lubricants; Models, Chemical; Pharmaceutical Preparations; Porosity; Pressure; Silicon Dioxide; Stearic Acids; Stress, Mechanical; Technology, Pharmaceutical; Tensile Strength; Transducers, Pressure | 2012 |
Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume.
Topics: Calcium Phosphates; Cellulose; Drug Compounding; Equipment Design; Excipients; Lactose; Lubrication; Stearic Acids; Tablets; Tensile Strength | 2012 |
Decoupling the role of image size and calorie intake on gastric retention of swelling-based gastric retentive formulations: pre-screening in the dog model.
Topics: Animals; Barium; Biological Availability; Cellulose; Delayed-Action Preparations; Diagnostic Imaging; Dogs; Drug Compounding; Energy Intake; Fasting; Food-Drug Interactions; Gastric Emptying; Hypromellose Derivatives; Lactose; Male; Metformin; Methylcellulose; Solubility; Stearic Acids | 2012 |
Pulmonary delivery of dry powders to rats: tolerability limits of an intra-tracheal administration model.
Topics: Animals; Drug Delivery Systems; Female; Insufflation; Lactose; Larynx; Lung; Powders; Rats; Rats, Sprague-Dawley; Stearic Acids; Trachea | 2012 |
Influence of compaction properties and interfacial topography on the performance of bilayer tablets.
Topics: Cellulose; Excipients; Lactose; Stearic Acids; Stress, Mechanical; Surface Properties; Tablets; Technology, Pharmaceutical; Tensile Strength | 2012 |
Prediction of the compressibility of complex mixtures of pharmaceutical powders.
Topics: Calcium Phosphates; Cellulose; Drug Compounding; Excipients; Lactose; Models, Theoretical; Particle Size; Povidone; Powders; Pressure; Stearic Acids | 2012 |
Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution.
Topics: Administration, Inhalation; Aerosols; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chromatography, Gas; Drug Compounding; Drug Delivery Systems; Drug Storage; Dry Powder Inhalers; Excipients; Humans; Indomethacin; Lactose; Microscopy, Electron, Scanning; Osmolar Concentration; Particle Size; Powders; Solvents; Stearic Acids; Surface Properties | 2012 |
Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets.
Topics: Air; Cellulose; Crystallization; Drug Compounding; Drug Storage; Humidity; Lactose; Pressure; Stearic Acids; Tablets; Temperature; Tensile Strength | 2012 |
Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy.
Topics: Cellulose; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Lactose; Methylcellulose; Pharmaceutical Preparations; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Water | 2013 |
In-line monitoring of the drug content of powder mixtures and tablets by near-infrared spectroscopy during the continuous direct compression tableting process.
Topics: Acetaminophen; Drug Compounding; Lactose; Powders; Spectroscopy, Near-Infrared; Stearic Acids; Tablets | 2013 |
Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics.
Topics: Algorithms; Cellulose; Chemistry, Pharmaceutical; Compressive Strength; Computer Simulation; Lactose; Mannitol; Models, Chemical; Neural Networks, Computer; Papaverine; Pharmaceutical Preparations; Powders; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Tensile Strength | 2013 |
Application of the combinative particle size reduction technology H 42 to produce fast dissolving glibenclamide tablets.
Topics: Chemistry, Pharmaceutical; Desiccation; Dioctyl Sulfosuccinic Acid; Glyburide; Hypoglycemic Agents; Lactose; Mannitol; Nanoparticles; Particle Size; Povidone; Pressure; Silicon Dioxide; Sodium Dodecyl Sulfate; Solubility; Stearic Acids; Tablets; Technology, Pharmaceutical | 2013 |
Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets.
Topics: Algorithms; Cellulose; Chemistry, Pharmaceutical; Elastic Modulus; Elasticity; Excipients; Lactose; Least-Squares Analysis; Lubricants; Models, Chemical; Molecular Structure; Particle Size; Scattering, Radiation; Starch; Stearic Acids; Stress, Mechanical; Tablets; Technology, Pharmaceutical; Transducers; Ultrasonics; Viscosity | 2013 |
Investigations into the tensile failure of doubly-convex cylindrical tablets under diametral loading using finite element methodology.
Topics: Chemistry, Pharmaceutical; Computer Simulation; Elasticity; Excipients; Finite Element Analysis; Glucose; Lactose; Linear Models; Models, Chemical; Polysaccharides, Bacterial; Stearic Acids; Stress, Mechanical; Tablets; Technology, Pharmaceutical; Tensile Strength | 2013 |
Direct compression of cushion-layered ethyl cellulose-coated extended release pellets into rapidly disintegrating tablets without changes in the release profile.
Topics: Carboxymethylcellulose Sodium; Cellulose; Delayed-Action Preparations; Drug Compounding; Excipients; Hardness; Lactose; Sorbitol; Stearic Acids; Tablets | 2013 |
Effects of powder flow properties on capsule filling weight uniformity.
Topics: Acetaminophen; Adhesiveness; Analgesics, Non-Narcotic; Capsules; Cellulose; Chemical Phenomena; Drug Compounding; Excipients; Lactose; Magnesium Silicates; Mechanical Phenomena; Particle Size; Powders; Quality Control; Rheology; Silicon Dioxide; Stearic Acids | 2013 |
A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose.
Topics: Cellulose; Excipients; Lactose; Lubricants; Poloxamer; Stearic Acids; Tablets; Technology, Pharmaceutical; Tensile Strength | 2013 |
Blending process modeling and control by multivariate curve resolution.
Topics: Acetaminophen; Algorithms; Calibration; Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Excipients; Humans; Lactose; Least-Squares Analysis; Multivariate Analysis; Reference Values; Spectrophotometry, Infrared; Stearic Acids | 2013 |
Energy-based analysis of cone milling process for the comminution of roller compacted flakes.
Topics: Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Lactose; Particle Size; Stearic Acids; Technology, Pharmaceutical | 2014 |
A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes.
Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Hardness; Ibuprofen; Lactose; Lubricants; Particle Size; Powders; Pressure; Solubility; Stearic Acids; Tablets; Theophylline | 2014 |
The influence of polymorphism on the manufacturability and in vitro dissolution of sulindac-containing hard gelatin capsules.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chemistry, Pharmaceutical; Crystallization; Drug Liberation; Excipients; Gelatin; Lactose; Powders; Solubility; Stearic Acids; Sulindac | 2015 |
Monitoring process induced attrition of drug substance particles within formulated blends.
Topics: Cellulose; Drug Compounding; Excipients; Lactose; Microscopy, Electron, Scanning; Particle Size; Pharmaceutical Preparations; Stearic Acids | 2014 |
Modeling strategies for pharmaceutical blend monitoring and end-point determination by near-infrared spectroscopy.
Topics: Acetaminophen; Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Least-Squares Analysis; Models, Theoretical; Principal Component Analysis; Spectroscopy, Near-Infrared; Stearic Acids | 2014 |
A method to evaluate the effect of contact with excipients on the surface crystallization of amorphous drugs.
Topics: Cellulose; Chemistry, Pharmaceutical; Crystallization; Excipients; Humidity; Indomethacin; Kinetics; Lactose; Mannitol; Nifedipine; Stearic Acids; Surface Properties; Tablets; Technology, Pharmaceutical; Water | 2014 |
Analysis of powder phenomena inside a Fette 3090 feed frame using in-line NIR spectroscopy.
Topics: Acetaminophen; Calibration; Equipment Design; Lactose; Models, Chemical; Particle Size; Powders; Reference Standards; Reproducibility of Results; Rheology; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical; Time Factors | 2014 |
Commercial scale validation of a process scale-up model for lubricant blending of pharmaceutical powders.
Topics: Algorithms; Calcium Phosphates; Cellulose; Chemical Phenomena; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Lactose; Lubricants; Lubrication; Mechanical Phenomena; Models, Chemical; Pharmaceutic Aids; Pharmaceutical Preparations; Quality Control; Reproducibility of Results; Stearic Acids; Tablets; Tensile Strength | 2014 |
Milk production responses to dietary stearic acid vary by production level in dairy cattle.
Topics: Animals; Body Weight; Cattle; Diet; Dietary Fiber; Dietary Supplements; Digestion; Fats; Fatty Acids; Fatty Acids, Nonesterified; Female; Lactation; Lactose; Medicago sativa; Milk; Silage; Stearic Acids; Zea mays | 2015 |
Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets.
Topics: Cellulose; Chemistry, Pharmaceutical; Excipients; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Lactose; Lubricants; Mannitol; Polyethylene Glycols; Povidone; Prednisone; Silicon Dioxide; Solubility; Stearic Acids; Tablets | 2016 |
Tablet mechanics depend on nano and micro scale adhesion, lubrication and structure.
Topics: Adhesiveness; Cellulose; Excipients; Hardness; Lactose; Lubrication; Mannitol; Powders; Stearic Acids; Tablets | 2015 |
Strategy for design NIR calibration sets based on process spectrum and model space: An innovative approach for process analytical technology.
Topics: Calibration; Cellulose; Cetirizine; Chemistry, Pharmaceutical; Drug Industry; Excipients; Lactose; Least-Squares Analysis; Principal Component Analysis; Quality Control; Silicon Dioxide; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical | 2015 |
In vitro and in vivo evaluations of buccal tablet formulations of ritodrine hydrochloride.
Topics: Administration, Buccal; Alginates; Animals; Cellulose; Chemistry, Pharmaceutical; Drug Liberation; Excipients; Glucuronic Acid; Hardness; Hexuronic Acids; Intestinal Absorption; Lactose; Male; Mouth; Rats, Wistar; Ritodrine; Solubility; Stearic Acids; Tablets | 2015 |
Modern evaluation of liquisolid systems with varying amounts of liquid phase prepared using two different methods.
Topics: Aluminum Compounds; Humans; Lactose; Magnesium Compounds; Polyethylene Glycols; Rosuvastatin Calcium; Silicates; Stearic Acids | 2015 |
Investigation into process-induced de-aggregation of cohesive micronised API particles.
Topics: Amidines; Cellulose; Lactose; Particle Size; Pyrazoles; Silicon Dioxide; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Stearic Acids; Technology, Pharmaceutical | 2015 |
Setting local rank constraints by orthogonal projections for image resolution analysis: application to the determination of a low dose pharmaceutical compound.
Topics: Cellulose; Indapamide; Lactose; Least-Squares Analysis; Models, Theoretical; Multivariate Analysis; Pharmaceutical Preparations; Principal Component Analysis; Spectrum Analysis, Raman; Stearic Acids; Tablets | 2015 |
Dry Powder Coating using Planetary Centrifugal Mixer.
Topics: Chemistry, Pharmaceutical; Excipients; Lactose; Particle Size; Powders; Stearic Acids; Surface Properties; X-Ray Diffraction | 2015 |
Reevaluation of the diametral compression test for tablets using the flattened disc geometry.
Topics: Calcium Phosphates; Finite Element Analysis; Lactose; Mannitol; Powders; Stearic Acids; Stress, Mechanical; Tablets; Technology, Pharmaceutical; Tensile Strength | 2016 |
Influence of the Punch Head Design on the Physical Quality of Tablets Produced in a Rotary Press.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Compressive Strength; Drug Compounding; Equipment Design; Excipients; Lactose; Starch; Stearic Acids; Tablets; Tensile Strength | 2017 |
Continuous monitoring of API content, API distribution and crushing strength after tableting via near-infrared chemical imaging.
Topics: Caffeine; Drug Compounding; Hardness; Lactose; Least-Squares Analysis; Povidone; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical | 2017 |
Application of Terahertz Attenuated Total Reflection Spectroscopy to Detect Changes in the Physical Properties of Lactose during the Lubrication Process Required for Drug Formulation.
Topics: Drug Compounding; Lactose; Lubrication; Pressure; Solubility; Stearic Acids; Tablets; Terahertz Spectroscopy; Time Factors | 2017 |
Investigation into the Manufacture and Properties of Inhalable High-Dose Dry Powders Produced by Comilling API and Lactose with Magnesium Stearate.
Topics: Administration, Inhalation; Aerosols; Dry Powder Inhalers; Lactose; Particle Size; Stearic Acids; Technology, Pharmaceutical | 2017 |
Co-milled API-lactose systems for inhalation therapy: impact of magnesium stearate on physico-chemical stability and aerosolization performance.
Topics: Administration, Inhalation; Adsorption; Aerosols; Drug Compounding; Drug Stability; Excipients; Humidity; Lactose; Particle Size; Powders; Respiratory Therapy; Stearic Acids | 2017 |
Investigation of Spatial Heterogeneity of Salt Disproportionation in Tablets by Synchrotron X-ray Diffractometry.
Topics: Carboxymethylcellulose Sodium; Cellulose; Excipients; Humidity; Lactose; Pioglitazone; Stearic Acids; Synchrotrons; Tablets; Temperature; Thiazolidinediones; Water; X-Ray Diffraction | 2017 |
Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data.
Topics: Cellulose; Lactose; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical | 2017 |
The suitability of common compressibility equations for characterizing plasticity of diverse powders.
Topics: Algorithms; Calcium Phosphates; Celecoxib; Cellulose; Compressive Strength; Excipients; Hardness; Ibuprofen; Lactose; Mannitol; Powders; Stearic Acids | 2017 |
Relationships between response surfaces for tablet characteristics of placebo and API-containing tablets manufactured by direct compression method.
Topics: Acetaminophen; Cellulose; Drug Compounding; Drug Design; Excipients; Lactose; Niacin; Placebos; Pressure; Pyridoxine; Salicylamides; Starch; Stearic Acids; Tablets | 2017 |
Differences in Powder Properties of Two 1,4-Dihydropyridine-Type Compounds Evaluated through Thermal Analysis.
Topics: Calorimetry, Differential Scanning; Compressive Strength; Dihydropyridines; Lactose; Nifedipine; Nitrobenzenes; Piperazines; Stearic Acids; Tablets; Temperature | 2017 |
Investigations on the Mechanism of Magnesium Stearate to Modify Aerosol Performance in Dry Powder Inhaled Formulations.
Topics: Administration, Inhalation; Aerosols; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Excipients; Lactose; Particle Size; Powders; Stearic Acids; Surface Properties | 2018 |
A drop penetration method to measure powder blend wettability.
Topics: Acetaminophen; Chemistry, Pharmaceutical; Dimethylpolysiloxanes; Excipients; Hydrophobic and Hydrophilic Interactions; Lactose; Lubricants; Powders; Stearic Acids; Surface Properties; Tablets; Water; Wettability | 2018 |
Modeling the effects of material properties on tablet compaction: A building block for controlling both batch and continuous pharmaceutical manufacturing processes.
Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Models, Theoretical; Stearic Acids; Tablets; Tensile Strength | 2018 |
A mechanistic study on tablet ejection force and its sensitivity to lubrication for pharmaceutical powders.
Topics: Calcium Phosphates; Drug Compounding; Excipients; Lactose; Lubrication; Mannitol; Mechanical Phenomena; Powders; Starch; Stearic Acids; Tablets | 2018 |
Limitations of high dose carrier based formulations.
Topics: Aerosols; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Beclomethasone; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Excipients; Glucocorticoids; Lactose; Microscopy, Electron, Scanning; Particle Size; Stearic Acids | 2018 |
Determining the Influence of Granule Size on Simulation Parameters and Residual Shear Stress Distribution in Tablets by Combining the Finite Element Method into the Design of Experiments.
Topics: Finite Element Analysis; Lactose; Molecular Dynamics Simulation; Particle Size; Stearic Acids; Surface Properties; Tablets | 2018 |
Rapid automated process development of a continuous capsule-filling process.
Topics: Ascorbic Acid; Capsules; Drug Compounding; Lactose; Stearic Acids | 2018 |
Deformation behavior of crystallized mannitol during compression using a rotary tablet press simulator.
Topics: Cellulose; Compressive Strength; Crystallization; Lactose; Mannitol; Models, Theoretical; Particle Size; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical | 2018 |
Towards quantitative prediction of the performance of dry powder inhalers by multi-scale simulations and experiments.
Topics: Aerosols; Budesonide; Computer Simulation; Dry Powder Inhalers; Hydrodynamics; Lactose; Models, Theoretical; Particle Size; Stearic Acids | 2018 |
Comparative evaluation of powder flow parameters with reference to particle size and shape.
Topics: Excipients; Lactose; Metformin; Multivariate Analysis; Particle Size; Povidone; Powders; Rheology; Stearic Acids; Stress, Mechanical | 2018 |
Understanding effects of process parameters and forced feeding on die filling.
Topics: Equipment Design; Excipients; Lactose; Particle Size; Powders; Rheology; Stearic Acids; Tablets; Technology, Pharmaceutical | 2018 |
A systematic evaluation of dual functionality of sodium lauryl sulfate as a tablet lubricant and wetting enhancer.
Topics: Celecoxib; Cellulose; Lactose; Lubricants; Sodium Dodecyl Sulfate; Stearic Acids; Surface-Active Agents; Tablets; Wettability | 2018 |
Influence of moisture variation on the performance of Raman spectroscopy in quantitative pharmaceutical analyses.
Topics: Acetaminophen; Administration, Oral; Calibration; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Humidity; Lactose; Models, Chemical; Spectrum Analysis, Raman; Stearic Acids | 2019 |
Evaluation of an in-line NIR spectroscopic method for the determination of the residence time in a tablet press.
Topics: Excipients; Lactose; Saccharin; Spectroscopy, Near-Infrared; Stearic Acids; Tablets; Technology, Pharmaceutical; Time Factors | 2019 |
Rapid Characterization of Formulated Pharmaceuticals Using Fast MAS
Topics: Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Cellulose; Drug Compounding; Excipients; Feasibility Studies; Hydrogen; Lactose; Mexiletine; Stearic Acids; Tablets; Theophylline; X-Ray Diffraction | 2019 |
Effect of coating time on inter- and intra-tablet coating uniformity.
Topics: Cellulose; Drug Compounding; Excipients; Lactose; Polyvinyls; Stearic Acids; Tablets; Time Factors; Titanium; X-Ray Microtomography | 2019 |
Assessing Particle Segregation Using Near-Infrared Chemical Imaging in Twin Screw Granulation.
Topics: Lactose; Particle Size; Powders; Stearic Acids; Technology, Pharmaceutical | 2019 |
Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach.
Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Cyproheptadine; Drug Compounding; Excipients; Fumarates; Lactose; Solubility; Starch; Stearic Acids; Tablets; Technology, Pharmaceutical | 2019 |
Parameter estimation for roller compaction process using an instrumented vector TF mini roller compactor.
Topics: Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Lactose; Models, Statistical; Placebos; Powders; Pressure; Silicon Dioxide; Stearic Acids | 2019 |
High Resolution Nanoscale Probing of Bacteriophages in an Inhalable Dry Powder Formulation for Pulmonary Infections.
Topics: Bacteriophages; Desiccation; Humans; Lactose; Microscopy, Atomic Force; Powders; Respiratory Tract Infections; Spectroscopy, Fourier Transform Infrared; Stearic Acids; Viral Proteins | 2019 |
Understanding the impact of magnesium stearate variability on tableting performance using a multivariate modeling approach.
Topics: Chemistry, Pharmaceutical; Excipients; Lactose; Lubricants; Lubrication; Particle Size; Spectroscopy, Near-Infrared; Spectrum Analysis, Raman; Stearic Acids; Tablets | 2020 |
Numerical study for tableting process in consideration of compression speed.
Topics: Acetaminophen; Cellulose; Computer Simulation; Excipients; Lactose; Models, Theoretical; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical | 2020 |
Investigation of the effects of particle size on fragmentation during tableting.
Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Particle Size; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical; Tensile Strength | 2020 |
A systematic evaluation of poloxamers as tablet lubricants.
Topics: Administration, Oral; Cellulose; Drug Compounding; Drug Liberation; Excipients; Kinetics; Lactose; Lubricants; Poloxamer; Ritonavir; Solubility; Stearic Acids; Tablets | 2020 |
Real-time quantification of low-dose cohesive formulations within a sampling interface for flowing powders.
Topics: Cellulose; Drug Compounding; Excipients; Ibuprofen; Lactose; Particle Size; Powders; Quality Control; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical | 2020 |
Evaluation of Weight Variation in Mini-Tablets Manufactured by a Multiple-Tip Tool.
Topics: Cellulose; Drug Compounding; Excipients; Lactose; Mannitol; Particle Size; Pressure; Starch; Stearic Acids; Surface Properties; Tablets | 2020 |
Comprehensive Insight into Chemical Stability of Important Antidiabetic Drug Vildagliptin Using Chromatography (LC-UV and UHPLC-DAD-MS) and Spectroscopy (Mid-IR and NIR with PCA).
Topics: Chromatography, Liquid; Dipeptidyl-Peptidase IV Inhibitors; Drug Stability; Excipients; Hot Temperature; Humidity; Hydrogen-Ion Concentration; Hypoglycemic Agents; Kinetics; Lactose; Mannitol; Mass Spectrometry; Oxidation-Reduction; Povidone; Principal Component Analysis; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stearic Acids; Vildagliptin | 2021 |
Exploring the influence of magnesium stearate content and mixing modality on the rheological properties and in vitro aerosolization of dry powder inhaler.
Topics: Administration, Inhalation; Aerosols; Drug Carriers; Dry Powder Inhalers; Fluticasone; Lactose; Particle Size; Powders | 2023 |
Impact of high shear blending on distribution of magnesium stearate on lactose for dry powder inhaled formulations.
Topics: Administration, Inhalation; Dry Powder Inhalers; Excipients; Gas Chromatography-Mass Spectrometry; Lactose; Particle Size; Powders | 2023 |