lactose has been researched along with n-acetylgalactosaminyl-1-4-n-acetylglucosamine in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (10.87) | 18.2507 |
| 2000's | 15 (32.61) | 29.6817 |
| 2010's | 22 (47.83) | 24.3611 |
| 2020's | 4 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Agterberg, M; Bakker, H; Neeleman, AP; Van den Eijnden, DH; Van der Knaap, WP; Van Die, I | 1 |
| Crout, DH; Packwood, J; Singh, S | 1 |
| Cummings, RD; Do, KY; Do, SI | 1 |
| Cummings, RD; Debose-Boyd, R; Long, TD; Nyame, AK; Tsang, VC | 1 |
| Cummings, RD; DeBose-Boyd, R; Leppanen, AM; Nyame, AK | 1 |
| Do, SI; Kim, HN; Lee, KY | 1 |
| Deelder, AM; Hokke, CH; van Dam, GJ; van den Eijnden, DH; van Die, I; van Remoortere, A | 1 |
| Bogitsh, BJ; Cummings, RD; Leppänen, AM; Nyame, AK | 1 |
| Coulson, PS; Cummings, RD; Eberl, M; Langermans, JA; Nyame, AK; Thomas, AW; Vervenne, RA; Wilson, RA | 1 |
| Hara-Kuge, S; Ohkura, T; Seko, A; Yamashita, K | 1 |
| Gotoh, M; Ishizuka, Y; Iwasaki, H; Kameyama, A; Kikuchi, N; Kiyohara, K; Kubota, T; Kudo, T; Nakanishi, H; Narimatsu, H; Ohkura, T; Sato, T; Togayachi, A | 1 |
| Gotoh, M; Ishizuka, Y; Iwai, T; Kameyama, A; Kikuchi, N; Kiyohara, K; Kwon, YD; Nakanishi, H; Narimatsu, H; Sato, T | 1 |
| Cummings, RD; Deelder, AM; Franke, N; Hokke, CH; Honing, H; Liu, FT; Schiphorst, WE; van den Berg, TK; van Die, I; van Remoortere, A | 1 |
| Conradt, HS; Mann, K; Nimtz, M | 1 |
| Cummings, RD; Dell, A; Haslam, SM; Kawar, ZS; Morris, HR | 1 |
| Deelder, AM; Hokke, CH; Koeleman, CA; Wuhrer, M | 1 |
| Aoki, C; Gotoh, M; Hirabayashi, J; Ikehara, SK; Ikehara, Y; Iwai, T; Kiyohara, K; Nakamura, S; Nakanishi, H; Narimatsu, H; Niwa, T; Sato, T; Tatematsu, M | 1 |
| Fuwa, TJ; Hirabayashi, Y; Ishida, H; Kinoshita-Toyoda, A; Nishihara, S; Sasaki, N; Toyoda, H; Ueda, R; Yoshida, H | 1 |
| Bakker, H; Berger, M; Deelder, AM; Gerardy-Schahn, R; Hokke, CH; Johswich, A; Kraft, B; Wuhrer, M | 1 |
| Adamiak, K; Bezouska, K; Bojarová, P; Elling, L; Kren, V; Krenek, K; Pelantová, H; Wetjen, K | 1 |
| Altevogt, P; Carilho, R; Conradt, HS; Costa, J; Kandzia, S; Machado, E | 1 |
| Hirano, K; Nishihara, S; Sasaki, N; Shinomi, M; Ui-Tei, K | 1 |
| Balog, CI; Deelder, AM; Doenhoff, MJ; Haas, H; Hokke, CH; Koeleman, CA; Meevissen, MH; Schramm, G; Wuhrer, M | 1 |
| Kos, J; Künzler, M; Magister, Š; Pohleven, J; Renko, M; Sabotič, J; Smith, DF; Štrukelj, B; Turk, D | 1 |
| Bonar, D; Breloy, I; Grahn, A; Hanisch, FG; Ottis, P; Pacharra, S | 1 |
| Chang, LY; Cheng, CW; Chou, CC; Fukuda, MN; Khoo, KH; Yu, SY | 1 |
| Hanisch, FG; Hoffmann, W; Kalbacher, H; Kalinski, T; Meyer, F; Ragge, H | 1 |
| Cummings, RD; Heimburg-Molinaro, J; Luyai, AE; Mandalasi, M; Mickum, M; Nyame, AK; Prasanphanich, NS; Smith, DF; Song, X | 1 |
| Cummings, RD; Heimburg-Molinaro, J; Lasanajak, Y; Luyai, AE; Mickum, ML; Nyame, AK; Prasanphanich, NS; Rivera-Marrero, CA; Secor, WE; Smith, DF; Song, X; Van Die, I; Wilkins, P | 1 |
| Furukawa, K; Hirano, K; Matsuda, A; Shirai, T | 1 |
| Bonar, D; Hanisch, FG | 1 |
| Ide, Y; Ishida, K; Kaneko, T; Kaya, T; Kojima, S; Nakamura, Y; Suda, Y; Yamashita, K | 1 |
| Blixt, O; Bovin, NV; Chen, K; Duus, JØ; Frederiksen, RF; Ingmer, H; Larsen, T; Leisner, JJ; Palcic, MM; Paspaliari, DK; Petersen, BO; Storgaard, BG; Westerlind, U; Yoshimura, Y | 1 |
| Kaji, H; Narimatsu, H; Sato, T; Sugahara, D; Tomioka, A | 1 |
| Böcker, S; Elling, L; Laaf, D | 1 |
| Burke, JE; Evans, SV; Gilbert, M; Haji-Ghassemi, O; Jenkins, ML; Parker, MJ; Schur, MJ; Spence, J; van Faassen, H; Young, NM | 1 |
| Hanzawa, K; Natsuka, S; Suzuki, N | 1 |
| Bojarová, P; Bumba, L; Elling, L; Křen, V; Laaf, D; Spiwok, V | 1 |
| Baba, S; Haga, Y; Inamura, K; Nonomura, N; Takeuchi, K; Ueda, K; Uemura, M | 1 |
| Duivenvoorden, W; Gardiner, RA; Hashimoto, Y; Hatakeyama, S; Ito, A; Kaneko, T; Kaya, T; Koie, T; Mitsuzuka, K; Mori, K; Ohyama, C; Okubo, T; Pinthus, JH; Suda, Y; Sutoh Yoneyama, M; Tobisawa, Y; Yoneyama, T | 1 |
| Artiaga, VG; Falcone, FH; Gellert, P; Overman, R; Paraskevopoulou, V; Rowlinson, R; Stolnik, S; Winkler, GS | 1 |
| Akamatsu, S; Goto, T; Inoue, T; Kaneko, T; Kaya, T; Kimura, H; Kobayashi, T; Muramatsu, S; Ogawa, O; Sawada, A; Yamasaki, T; Yoshino, T | 1 |
| Kos, J; Sabotič, J | 1 |
| Cabrita, EJ; Carvalho, AL; Coelho, H; Corzana, F; Dias, JS; Diniz, A; Gimeno, A; Jiménez-Barbero, J; Lima, CDL; Marcelo, F; Trovão, F | 1 |
| Belan, V; Bertok, T; Bertokova, A; Ďubjaková, P; Fillo, J; Hires, M; Jane, E; Novotná, O; Tkac, J | 1 |
| Dang, L; Hu, L; Jia, L; Li, J; Liu, D; Ma, C; Mu, F; Shen, J; Sun, S; Zhao, T; Zhu, B | 1 |
3 review(s) available for lactose and n-acetylgalactosaminyl-1-4-n-acetylglucosamine
| Article | Year |
|---|---|
Novel glycosylation routes for glycoproteins: the lacdiNAc pathway.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Disaccharides; Glycoproteins; Glycosylation; Humans; Lactose; Molecular Sequence Data; Oligosaccharides; Recombinant Proteins | 1995 |
Expression of LacdiNAc groups on N-glycans among human tumors is complex.
Topics: Cell Transformation, Neoplastic; Humans; Lactose; Neoplasms; Polysaccharides | 2014 |
CNL-
Topics: Agaricales; Animals; Fungal Proteins; Lactose; Lectins | 2019 |
43 other study(ies) available for lactose and n-acetylgalactosaminyl-1-4-n-acetylglucosamine
| Article | Year |
|---|---|
Enzymatic synthesis of 2-acetamido-4-O-(2-acetamido-2-deoxy-beta-D- galactopyranosyl)-2-deoxy-D-glucopyranose and 2-acetamido-6-O-(2-acetamido-2- deoxy-beta-D-galactopyranosyl)-2-deoxy-D-glucopyranose catalysed by the beta-N-acetylhexosaminidase from Aspe
Topics: Aspergillus oryzae; beta-N-Acetylhexosaminidases; Carbohydrate Conformation; Carbohydrate Sequence; Chromatography; Disaccharides; Fabaceae; Lactose; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Plants, Medicinal | 1995 |
Differential expression of LacdiNAc sequences (GalNAc beta 1-4GlcNAc-R) in glycoproteins synthesized by Chinese hamster ovary and human 293 cells.
Topics: Animals; Antigens, CD; CHO Cells; Chromatography, Affinity; Cricetinae; Disaccharides; Flow Cytometry; Glycopeptides; Glycoproteins; Humans; Lactose; Lectins; Lysosomal Membrane Proteins; Membrane Glycoproteins; N-Acetylgalactosaminyltransferases; Plant Lectins; Polypeptide N-acetylgalactosaminyltransferase; Protein Processing, Post-Translational; Receptors, N-Acetylglucosamine; Species Specificity; Substrate Specificity | 1997 |
Expression of Lex antigen in Schistosoma japonicum and S.haematobium and immune responses to Lex in infected animals: lack of Lex expression in other trematodes and nematodes.
Topics: Animals; Antibodies, Helminth; Antibody Formation; Antigens, Helminth; Blood; COS Cells; Disaccharides; Glycoconjugates; Glycoproteins; Helminth Proteins; Helminths; Humans; Lactose; Lewis Blood Group Antigens; Lewis X Antigen; Nematoda; Rodentia; Schistosoma haematobium; Schistosoma japonicum; Schistosomiasis; Trematoda | 1998 |
Mice infected with Schistosoma mansoni generate antibodies to LacdiNAc (GalNAc beta 1-->4GlcNAc) determinants.
Topics: Animals; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helminth; Carbohydrate Sequence; Cattle; Disaccharides; Glycoproteins; Helminth Proteins; Immunoglobulin M; Lactose; Mice; Molecular Sequence Data; Oligosaccharides; Polysaccharides; Schistosoma mansoni; Schistosomiasis mansoni | 1999 |
Novel induction of alpha-lactalbumin-mediated lacdiNAc-R expression in vivo.
Topics: Amidohydrolases; Animals; Biomarkers, Tumor; Cattle; Cells, Cultured; CHO Cells; Cricetinae; Disaccharides; Glucosamine; Glycopeptides; Immunoblotting; Lactalbumin; Lactose; N-Acetylgalactosaminyltransferases; Oligopeptides; Oligosaccharides; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tritium | 2000 |
Various stages of schistosoma express Lewis(x), LacdiNAc, GalNAcbeta1-4 (Fucalpha1-3)GlcNAc and GalNAcbeta1-4(Fucalpha1-2Fucalpha1-3)GlcNAc carbohydrate epitopes: detection with monoclonal antibodies that are characterized by enzymatically synthesized neo
Topics: Animals; Antibodies, Monoclonal; Cricetinae; Disaccharides; Epitopes; Fluorescent Antibody Technique, Indirect; Fucose; Glycoproteins; Lactose; Lewis X Antigen; Mice; Schistosoma mansoni; Schistosomiasis mansoni; Surface Plasmon Resonance; Tissue Distribution | 2000 |
Antibody responses to the fucosylated LacdiNAc glycan antigen in Schistosoma mansoni-infected mice and expression of the glycan among schistosomes.
Topics: Animals; Antibodies, Helminth; Antibodies, Monoclonal; Antigens, Helminth; Blotting, Western; Carbohydrate Sequence; Disaccharides; Enzyme-Linked Immunosorbent Assay; Female; Glycoproteins; Humans; Hybridomas; Immunoglobulin G; Immunohistochemistry; Lactose; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Polysaccharides; Schistosoma mansoni; Schistosomiasis mansoni | 2000 |
Antibodies to glycans dominate the host response to schistosome larvae and eggs: is their role protective or subversive?
Topics: Animals; Antibodies, Helminth; Antibody Formation; Antibody Specificity; Antigens, Helminth; Cross Reactions; Disaccharides; Epitopes; Female; Immunity, Cellular; Immunoglobulin G; Immunoglobulin M; Lactose; Larva; Lewis X Antigen; Male; Oocytes; Oviposition; Pan troglodytes; Polysaccharides; Schistosoma; Time Factors | 2001 |
Occurrence of secretory glycoprotein-specific GalNAc beta 1-->4GlcNAc sequence in N-glycans in MDCK cells.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cell Fractionation; Cell Line; Disaccharides; Dogs; Glucosamine; Glycoproteins; Humans; Kidney; Lactose; N-Acetylgalactosaminyltransferases; Oligosaccharides; Plant Lectins; Tritium | 2002 |
Molecular cloning and characterization of a novel human beta 1,4-N-acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAc.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbohydrate Sequence; Cell Line; Chromatography, High Pressure Liquid; Cloning, Molecular; Databases, Genetic; Disaccharides; DNA, Complementary; Glucuronosyltransferase; Glycosyltransferases; Humans; Lactose; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Models, Genetic; Molecular Sequence Data; Multifunctional Enzymes; N-Acetylgalactosaminyltransferases; Open Reading Frames; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phylogeny; Polypeptide N-acetylgalactosaminyltransferase; Polysaccharides; Protein Structure, Tertiary; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Time Factors; Tissue Distribution | 2003 |
Molecular cloning and characterization of beta1,4-N-acetylgalactosaminyltransferases IV synthesizing N,N'-diacetyllactosediamine.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbohydrate Sequence; Cell Line; Cloning, Molecular; Disaccharides; Humans; Lactose; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Sequence Alignment; Substrate Specificity; Tissue Distribution | 2004 |
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition.
Topics: Animals; Antigens, Helminth; Cell Line; Cricetinae; Disaccharides; Galectin 1; Galectin 3; Glycoconjugates; Humans; Lactose; Macrophages; Male; Mesocricetus; Phagocytosis; Polysaccharides; Protein Binding; Rats; Rats, Wistar; Recombinant Fusion Proteins; Schistosoma mansoni; Schistosomiasis mansoni; Surface Plasmon Resonance | 2004 |
LacdiNAc (GalNAcbeta1-4GlcNAc) is a major motif in N-glycan structures of the chicken eggshell protein ovocleidin-116.
Topics: Animals; Asparagine; Carbohydrate Sequence; Chickens; Chromatography, High Pressure Liquid; Disaccharides; Egg Proteins; Endopeptidases; Fucose; Lactose; Methylation; Molecular Sequence Data; Oligosaccharides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
Novel poly-GalNAcbeta1-4GlcNAc (LacdiNAc) and fucosylated poly-LacdiNAc N-glycans from mammalian cells expressing beta1,4-N-acetylgalactosaminyltransferase and alpha1,3-fucosyltransferase.
Topics: Amino Acid Motifs; Animals; Blotting, Western; Caenorhabditis elegans; Carbohydrate Conformation; CHO Cells; Cricetinae; Disaccharides; Electrophoresis, Polyacrylamide Gel; Fucose; Fucosyltransferases; Gas Chromatography-Mass Spectrometry; Glycoproteins; Humans; Lactose; Mass Spectrometry; N-Acetylgalactosaminyltransferases; Open Reading Frames; Polysaccharides; Promoter Regions, Genetic; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Disaccharides; Fucose; Lactose; Molecular Sequence Data; Polysaccharides; Schistosoma mansoni; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
Apical Golgi localization of N,N'-diacetyllactosediamine synthase, beta4GalNAc-T3, is responsible for LacdiNAc expression on gastric mucosa.
Topics: Antigens, Differentiation; Cell Line, Tumor; Disaccharides; Gastric Mucosa; Golgi Apparatus; Humans; Lactose; N-Acetylgalactosaminyltransferases | 2006 |
Drosophila beta 1,4-N-acetylgalactosaminyltransferase-A synthesizes the LacdiNAc structures on several glycoproteins and glycosphingolipids.
Topics: Animals; Carbohydrate Sequence; Disaccharides; Drosophila Proteins; Glycoproteins; Glycosphingolipids; Lactose; Molecular Sequence Data; N-Acetylgalactosaminyltransferases | 2007 |
Golgi targeting of Drosophila melanogaster beta4GalNAcTB requires a DHHC protein family-related protein as a pilot.
Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Drosophila melanogaster; Drosophila Proteins; Endoplasmic Reticulum; Gene Library; Glycolipids; Glycosylation; Golgi Apparatus; Humans; Lactose; Membrane Proteins; N-Acetylgalactosaminyltransferases; Octoxynol; Protein Interaction Mapping; Protein Transport; Saponins | 2009 |
Synthesis of LacdiNAc-terminated glycoconjugates by mutant galactosyltransferase--a way to new glycodrugs and materials.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bacterial Proteins; Campylobacter jejuni; Carbohydrate Epimerases; Female; Galactosyltransferases; Glycoconjugates; Humans; Lactose; Lectins, C-Type; Mutation; NK Cell Lectin-Like Receptor Subfamily B; Placenta; Pregnancy; Substrate Specificity | 2009 |
N-Glycosylation of total cellular glycoproteins from the human ovarian carcinoma SKOV3 cell line and of recombinantly expressed human erythropoietin.
Topics: Biomarkers, Tumor; Erythropoietin; Female; Glycoproteins; Glycosylation; Humans; Lactose; Mannose; Molecular Structure; Ovarian Neoplasms; Polysaccharides; Recombinant Proteins; Tumor Cells, Cultured | 2011 |
LacdiNAc (GalNAcβ1-4GlcNAc) contributes to self-renewal of mouse embryonic stem cells by regulating leukemia inhibitory factor/STAT3 signaling.
Topics: Animals; Caveolin 1; Cell Differentiation; Cells, Cultured; Cytokine Receptor gp130; Embryonic Stem Cells; Flow Cytometry; Gene Knockdown Techniques; Immunoblotting; Lactose; Leukemia Inhibitory Factor; Leukemia Inhibitory Factor Receptor alpha Subunit; Membrane Glycoproteins; Mice; N-Acetylgalactosaminyltransferases; Pluripotent Stem Cells; Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor | 2011 |
Targeted glycoproteomic analysis reveals that kappa-5 is a major, uniquely glycosylated component of Schistosoma mansoni egg antigens.
Topics: Amino Acid Motifs; Animals; Antibodies, Helminth; Antigens, Helminth; Egg Proteins; Glycoproteins; Glycoside Hydrolases; Glycosylation; Helminth Proteins; Host-Parasite Interactions; Humans; Immunoglobulin E; Lactose; Peptide Fragments; Polysaccharides; Schistosoma mansoni; Schistosomiasis mansoni; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2011 |
Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAcβ1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis.
Topics: ABO Blood-Group System; Agaricales; Amino Acid Sequence; Animals; Caenorhabditis elegans; Crystallography, X-Ray; Erythrocytes; Escherichia coli; Humans; Jurkat Cells; Lactose; Molecular Sequence Data; Mutation; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Recombinant Proteins; Ricin | 2012 |
O-linked N,N'-diacetyllactosamine (LacdiNAc)-modified glycans in extracellular matrix glycoproteins are specifically phosphorylated at subterminal N-acetylglucosamine.
Topics: Acetylglucosamine; Amino Acid Sequence; Animals; Blotting, Western; Cattle; Cell Line; Egg Proteins; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix Proteins; Humans; Lactose; Mass Spectrometry; Membrane Glycoproteins; Molecular Sequence Data; Phosphorylation; Polysaccharides; Receptors, Cell Surface; Zona Pellucida Glycoproteins | 2012 |
Priming mass spectrometry-based sulfoglycomic mapping for identification of terminal sulfated lacdiNAc glycotope.
Topics: Animals; Cattle; Lactose; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thyrotropin | 2013 |
Human gastric TFF2 peptide contains an N-linked fucosylated N,N'-diacetyllactosediamine (LacdiNAc) oligosaccharide.
Topics: Amino Acid Sequence; Humans; Lactose; Oligosaccharides; Peptides; Plant Lectins; Receptors, N-Acetylglucosamine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trefoil Factor-2 | 2013 |
Immunization with recombinantly expressed glycan antigens from Schistosoma mansoni induces glycan-specific antibodies against the parasite.
Topics: Animals; Antibodies, Helminth; Antigen Presentation; Cell Engineering; CHO Cells; Cricetinae; Cricetulus; Immunization; Immunoglobulin G; Lactose; Mice; Schistosoma mansoni; Schistosomiasis mansoni | 2014 |
Differential expression of anti-glycan antibodies in schistosome-infected humans, rhesus monkeys and mice.
Topics: Adult; Animals; Antibodies, Helminth; Epitopes; Humans; Immunoglobulin G; Lactose; Macaca mulatta; Mice; Praziquantel; Schistosomiasis mansoni; Species Specificity | 2014 |
Trefoil factor family domains represent highly efficient conformational determinants for N-linked N,N'-di-N-acetyllactosediamine (LacdiNAc) synthesis.
Topics: Amino Acid Sequence; Animals; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Glycomics; Glycoproteins; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Immunohistochemistry; Lactose; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Peptides; Point Mutation; Polysaccharides; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Sus scrofa; Trefoil Factor-2 | 2014 |
High-sensitivity immunoassay with surface plasmon field-enhanced fluorescence spectroscopy using a plastic sensor chip: application to quantitative analysis of total prostate-specific antigen and GalNAcβ1-4GlcNAc-linked prostate-specific antigen for prost
Topics: Equipment Design; Humans; Immunoassay; Lactose; Limit of Detection; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Spectrometry, Fluorescence | 2015 |
A diverse range of bacterial and eukaryotic chitinases hydrolyzes the LacNAc (Galβ1-4GlcNAc) and LacdiNAc (GalNAcβ1-4GlcNAc) motifs found on vertebrate and insect cells.
Topics: Amino Sugars; Animals; Bacterial Proteins; Carbohydrate Sequence; Chitin; Chitinases; Genetic Variation; Humans; Hydrolysis; Insect Proteins; Insecta; Kinetics; Lactose; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Phylogeny; Polysaccharides; Protein Binding; Rhodamines; Salmonella typhimurium; Substrate Specificity; Vertebrates | 2015 |
Large-scale identification of secretome glycoproteins recognized by Wisteria floribunda agglutinin: A glycoproteomic approach to biomarker discovery.
Topics: Biomarkers, Tumor; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Chromatography, Liquid; Culture Media; Glycomics; Glycoproteins; HEK293 Cells; Humans; Lactose; Molecular Sequence Data; Plant Lectins; Proteomics; Receptors, N-Acetylglucosamine; Tandem Mass Spectrometry | 2015 |
Galectin Binding to Neo-Glycoproteins: LacDiNAc Conjugated BSA as Ligand for Human Galectin-3.
Topics: Animals; Carbohydrate Conformation; Cattle; Galectin 1; Galectin 3; Glycoproteins; Humans; Lactose; Ligands; Models, Molecular; Protein Binding; Serum Albumin, Bovine | 2015 |
Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin.
Topics: Biomarkers, Tumor; Crystallography, X-Ray; Humans; Lactose; Plant Lectins; Protein Binding; Protein Domains; Protein Structure, Secondary; Wisteria | 2016 |
Structures and developmental alterations of N-glycans of zebrafish embryos.
Topics: Animals; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Embryo, Nonmammalian; Embryonic Development; Galactosyltransferases; Gastrula; Glycosylation; Lactose; Polysaccharides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Zebrafish | 2017 |
Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling.
Topics: Binding Sites; Galectin 3; Glycoproteins; Humans; Lactose; Ligands; Molecular Docking Simulation; Protein Binding; Serum Albumin, Bovine | 2018 |
Identification of Multisialylated LacdiNAc Structures as Highly Prostate Cancer Specific Glycan Signatures on PSA.
Topics: Aged; Algorithms; Biomarkers, Tumor; Humans; Kallikreins; Lactose; Male; Middle Aged; Neoplasm Grading; Polysaccharides; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; ROC Curve; Sialic Acids; Sialoglycoproteins | 2019 |
Clinical significance of the LacdiNAc-glycosylated prostate-specific antigen assay for prostate cancer detection.
Topics: Aged; Glycosylation; Humans; Lactose; Male; Middle Aged; Neoplasm Grading; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Retrospective Studies; ROC Curve; Tumor Burden | 2019 |
Introduction of a C-terminal hexa-lysine tag increases thermal stability of the LacDiNac binding adhesin (LabA) exodomain from Helicobacter pylori.
Topics: Adhesins, Bacterial; Cloning, Molecular; Escherichia coli; Helicobacter pylori; Hexosaminidase A; Lactose; Lysine; Mass Spectrometry; Models, Molecular; Periplasm; Protein Binding; Protein Stability; Protein Structure, Secondary | 2019 |
LacdiNAc-Glycosylated Prostate-specific Antigen Density is a Potential Biomarker of Prostate Cancer.
Topics: Aged; Biopsy; Glycosylation; Humans; Kallikreins; Lactose; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Retrospective Studies; ROC Curve | 2020 |
Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins.
Topics: Epitopes; Humans; Lactose; Neoplasms; Polysaccharides; Protein Binding | 2021 |
Detection of N,N-diacetyllactosamine (LacdiNAc) containing free prostate-specific antigen for early stage prostate cancer diagnostics and for identification of castration-resistant prostate cancer patients.
Topics: Aged; Biomarkers, Tumor; Cohort Studies; Diagnosis, Differential; Early Detection of Cancer; Enzyme-Linked Immunosorbent Assay; Humans; Lactose; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms, Castration-Resistant | 2021 |
Precision N-glycoproteomics reveals elevated LacdiNAc as a novel signature of intrahepatic cholangiocarcinoma.
Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholangiocarcinoma; Humans; Lactose; Liver Neoplasms; Polysaccharides | 2022 |