lactic acid and zalcitabine

lactic acid has been researched along with zalcitabine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's3 (30.00)18.2507
2000's5 (50.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, CH; Cheng, YC1
Colacino, JM; Jaskunas, SR; Malcolm, SK1
Bennett, LL; Parker, WB; Shaddix, SC; Vince, R1
Hobbs, GA; Keilbaugh, SA; Simpson, MV1
Lebrecht, D; Setzer, B; Venhoff, N; Walker, UA1
Bäuerle, J; Gatell, JM; Laguno, M; Mallolas, J; Mauss, S; Miquel, R; Murillas, J; Schmutz, G; Setzer, B; Walker, UA1
Schlesier, M; Setzer, B; Thomas, AK; Walker, UA1
de Baar, MP; de Ronde, A; Ruiter, JP; Tebas, P; Timmermans, EC; Wanders, RJ1
Armand, R; Kintner, J; Lewis, LD; Perez, R; Yeo, TK1

Other Studies

10 other study(ies) available for lactic acid and zalcitabine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine.
    The Journal of biological chemistry, 1989, Jul-15, Volume: 264, Issue:20

    Topics: Antiviral Agents; Cell Line; Cell Survival; Deoxyribonuclease BamHI; Dideoxynucleosides; DNA, Mitochondrial; Electrophoresis, Agar Gel; HIV; Lactates; Lactic Acid; Zalcitabine

1989
Effect of fialuridine on replication of mitochondrial DNA in CEM cells and in human hepatoblastoma cells in culture.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:9

    Topics: Antiviral Agents; Arabinofuranosyluracil; Cells, Cultured; DNA Replication; DNA, Mitochondrial; Hepatoblastoma; Humans; Lactates; Lactic Acid; Liver Neoplasms; T-Lymphocytes; Tumor Cells, Cultured; Zalcitabine

1994
Lack of mitochondrial toxicity in CEM cells treated with carbovir.
    Antiviral research, 1997, Volume: 34, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Dideoxynucleosides; DNA, Mitochondrial; Drug Evaluation, Preclinical; Humans; Lactic Acid; Mitochondria; Prodrugs; Zalcitabine

1997
Effect of 2',3'-dideoxycytidine on oxidative phosphorylation in the PC12 cell, a neuronal model.
    Biochemical pharmacology, 1997, May-15, Volume: 53, Issue:10

    Topics: Animals; Antimetabolites; Cell Division; DNA, Mitochondrial; Lactic Acid; Models, Biological; Neurons; Oxidative Phosphorylation; PC12 Cells; Rats; Zalcitabine

1997
Dietary supplements in the treatment of nucleoside reverse transcriptase inhibitor-related mitochondrial toxicity.
    AIDS (London, England), 2002, Mar-29, Volume: 16, Issue:5

    Topics: Anti-HIV Agents; Ascorbic Acid; Carnitine; Cell Survival; Dietary Supplements; DNA, Mitochondrial; Electron Transport Complex IV; Humans; Lactic Acid; Lipid Metabolism; Mitochondria; Nucleosides; Riboflavin; RNA-Directed DNA Polymerase; Thiamine; Tumor Cells, Cultured; Zalcitabine

2002
Depletion of mitochondrial DNA in liver under antiretroviral therapy with didanosine, stavudine, or zalcitabine.
    Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:2

    Topics: Acidosis, Lactic; Adult; Cross-Sectional Studies; Didanosine; DNA, Mitochondrial; Female; Hepatitis C, Chronic; HIV Infections; Humans; Lactic Acid; Liver; Male; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine

2004
Mitochondrial toxicity of nucleoside analogues in primary human lymphocytes.
    Antiviral therapy, 2005, Volume: 10, Issue:2

    Topics: CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Didanosine; DNA, Mitochondrial; Female; Humans; Lactic Acid; Lymphocyte Activation; Male; Mitochondrial Diseases; Reverse Transcriptase Inhibitors; Stavudine; Zalcitabine

2005
Real-time nucleic acid sequence-based amplification assay to quantify changes in mitochondrial DNA concentrations in cell cultures and blood cells from HIV-infected patients receiving antiviral therapy.
    Clinical chemistry, 2006, Volume: 52, Issue:6

    Topics: Anti-HIV Agents; Base Sequence; Blood Platelets; Cell Nucleus; Cells, Cultured; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Feasibility Studies; Fibroblasts; HIV Infections; Humans; Indinavir; Lactic Acid; Lamivudine; Leukocytes, Mononuclear; Nucleic Acid Amplification Techniques; Pyruvic Acid; Stavudine; Zalcitabine

2006
Sublethal concentrations of gemcitabine (2',2'-difluorodeoxycytidine) alter mitochondrial ultrastructure and function without reducing mitochondrial DNA content in BxPC-3 human pancreatic carcinoma cells.
    Human & experimental toxicology, 2007, Volume: 26, Issue:12

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Deoxycytidine; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Inhibitory Concentration 50; Lactic Acid; Mitochondria; Pancreatic Neoplasms; Reverse Transcriptase Inhibitors; Zalcitabine

2007