lactic acid has been researched along with verapamil in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (30.00) | 18.7374 |
| 1990's | 12 (30.00) | 18.2507 |
| 2000's | 5 (12.50) | 29.6817 |
| 2010's | 11 (27.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Futaki, S; Nozawa, T; Suga, H; Tanaka, N; Yasumura, Y | 1 |
| Bittar, G; Dominguez, A; Friedman, HS; Vorperian, V | 1 |
| Broxterman, HJ; Lankelma, J; Pinedo, HM; Schuurhuis, GJ | 1 |
| Erecińska, M; Rumsey, WL; Wilson, DF | 1 |
| Broxterman, HJ; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ | 1 |
| Best, L; Lynch, AM; Meats, JE; Tomlinson, S; Tuersley, MD | 1 |
| Baroni, S; Cardillo, C; Folli, G; Musumeci, V; Tutinelli, F; Zappacosta, B; Zuppi, C | 1 |
| Klein, HH; Kreuzer, H; Schmid, M; Tebbe, U; Werner, GS; Wiegand, V | 1 |
| Watts, JA | 1 |
| Ginsburg, ME; Hicks, GL; Ouriel, K; Patti, CS; Pearce, FJ | 1 |
| Heinle, H; Reich, A | 1 |
| Laustiola, K; Lilius, EM; Metsä-Ketelä, T; Vapaatalo, H | 1 |
| Hattori, S; Miyazaki, T; Mori, H; Nagata, M; Nakamura, Y; Ogawa, S; Sakurai, K; Takahashi, M | 1 |
| Baller, D; Hellige, G; Hoeft, A; Korb, H; Schräder, R; Wolpers, HG | 1 |
| Csik, V; Szekeres, L; Udvary, E | 1 |
| Goshima, K; Kishi, T; Kubota, N; Okamoto, T; Takahashi, T; Takahata, K | 1 |
| Kopsidas, G; MacPhee, DG | 1 |
| Kline, JA; Raymond, RM; Schroeder, JD; Tomaszewski, CA | 1 |
| Karasawa, A; Kubo, K; Shirakura, S | 1 |
| Aksnes, G; Christensen, G; Leistad, E; Verburg, E | 1 |
| Kline, JA; Leonova, E; Schroeder, JD; Watts, JA; Williams, TC | 1 |
| Kline, JA; Leonova, ED; Raymond, RM; Watts, JA; Williams, TC | 1 |
| Nagao, T; Sato, R; Yamazaki, J | 1 |
| Ikeda, M; Koshika, A; Miyajima, M; Okada, J | 1 |
| Baumgart, D; Brauck, K; Eggebrecht, H; Erbel, R; Gutersohn, A; Haude, M; Oldenburg, O; Schaar, J | 1 |
| Aänismaa, P; Gatlik-Landwojtowicz, E; Seelig, A | 1 |
| Chavanpatil, MD; Panyam, J; Patil, Y | 1 |
| Bi, Y; Cai, Z; Chen, Q; Hou, S; Li, Y; Song, X; Wu, W; Zhao, Y | 1 |
| Cai, Z; Cui, FY; Gong, DQ; He, G; Hou, SX; Lei, XJ; Song, XR; Wei, YQ; Xiong, SJ; Zheng, Y | 1 |
| He, G; He, ZY; Hou, SX; Li, JM; Li, SZ; Luo, X; Luo, YF; Song, XR; Wei, YQ; Yang, L; Yu, S; Zheng, Y | 1 |
| Chen, HY; Hsu, CY; Huang, FH; Huang, LY; Lai, PS; Shieh, MJ | 1 |
| Heinzle, E; Niklas, J; Noor, F; Pironti, A; Strigun, A; Yang, TH | 1 |
| An, BM; Choy, YB; Kim, MH; Lee, JE; Lee, SH; Park, CG; Park, M | 1 |
| Gao, FY; Ma, M; Shen, JM; Yang, YJ; Yin, T; Yue, F; Zhang, HX | 1 |
| Chen, Y; Fang, DL; Lei, Y; Li, HL; Ren, K; Song, XR; Xu, B; Yang, Y; Zhang, JK; Zheng, XL | 1 |
| Curtis, MJ; Eykyn, TR; Masoud, R; O'Brien, BA; Wilder, CD; Yazar, D | 1 |
| Al-Enazy, S; Albekairi, NA; Ali, S; Rytting, E | 1 |
| Abbasova, K; Anshakova, A; Baklaushev, V; Balabanyan, V; Chekhonin, V; Gelperina, S; Kreuter, J; Maksimenko, O; Malinovskaya, J; Melnikov, P; Titov, S; Zybina, A | 1 |
| Amin, MM; El Gazayerly, ON; Elshafeey, AH; Yousry, C | 1 |
3 trial(s) available for lactic acid and verapamil
| Article | Year |
|---|---|
Effects of calcium channel blockers on the endothelial release of von Willebrand factor after exercise in healthy subjects.
Topics: Adult; Antigens; Blood; Blood Pressure; Endothelium, Vascular; Exercise; Heart Rate; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Nicardipine; Verapamil; von Willebrand Factor | 1989 |
[The cardioprotective effect of verapamil in acute percutaneous transluminal coronary angioplasty].
Topics: Adult; Aged; Angina Pectoris; Angioplasty, Balloon; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; Electrocardiography; Female; Heart Conduction System; Humans; Injections; Lactates; Lactic Acid; Male; Middle Aged; Myocardium; Oxygen Consumption; Verapamil | 1988 |
Myocardial lactate release after intracoronary verapamil application in humans: acute effects of intracoronary verapamil on systemic and coronary hemodynamics, myocardial metabolism, and norepinephrine levels.
Topics: Adult; Aged; Blood Glucose; Calcium Channel Blockers; Coronary Angiography; Coronary Circulation; Coronary Vessels; Fatty Acids, Nonesterified; Female; Hemodynamics; Humans; Injections; Lactic Acid; Male; Middle Aged; Myocardium; Norepinephrine; Verapamil | 2001 |
37 other study(ies) available for lactic acid and verapamil
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effects of bigeminies and paired-pulse stimulation on oxygen consumption in dog left ventricle.
Topics: Animals; Blood Pressure; Blood Volume; Calcium Chloride; Cardiac Complexes, Premature; Dogs; Electric Stimulation; Heart; Heart Ventricles; Homeostasis; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Models, Cardiovascular; Myocardial Contraction; Myocardium; Oxygen Consumption; Pulse; Time Factors; Verapamil | 1990 |
Theophylline produces an adverse effect on myocardial lactate metabolism at a therapeutic serum concentration: an effect blocked by verapamil.
Topics: Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; Lactates; Lactic Acid; Myocardial Contraction; Myocardium; Oxygen Consumption; Theophylline; Verapamil | 1991 |
Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Cell Line; Cyclosporins; Daunorubicin; Drug Resistance; Energy Metabolism; Female; Humans; Lactates; Lactic Acid; Ovarian Neoplasms; Verapamil | 1990 |
Relationship of myocardial metabolism and coronary flow: dependence on extracellular calcium.
Topics: Adenosine Triphosphate; Amobarbital; Animals; Calcium; Calcium Channel Blockers; Coronary Circulation; Hypoxia; Ion Channels; Lactates; Lactic Acid; Male; Mathematics; Myocardium; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Glycolysis in P-glycoprotein-overexpressing human tumor cell lines. Effects of resistance-modifying agents.
Topics: Adenosine Triphosphate; Amiloride; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Proteins; Chloroquine; Cytochalasin B; Drug Resistance; Energy Metabolism; Glutathione Transferase; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Membrane Glycoproteins; Monensin; Nigericin; Oxygen Consumption; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil | 1989 |
Lactate alters plasma membrane potential, increases the concentration of cytosolic Ca2+ and stimulates the secretion of insulin by the hamster beta-cell line HIT-T15.
Topics: Acetates; Acetic Acid; Animals; Calcium; Cell Line; Cricetinae; Cytosol; Glucose; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; Membrane Potentials; Potassium; Tolbutamide; Valinomycin; Verapamil | 1989 |
Protection of ischemic hearts by Ca2+ antagonists.
Topics: Animals; Bepridil; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Energy Metabolism; Lactates; Lactic Acid; Mitochondria, Heart; Myocardial Contraction; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Verapamil crystalloid cardioplegia: an experimental evaluation of dose-response relationships.
Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Heart Arrest, Induced; Hemodynamics; Lactates; Lactic Acid; Mathematics; Oxygen Consumption; Rabbits; Regional Blood Flow; Verapamil | 1987 |
Inhibition by verapamil of the medium change induced stimulation of cultured vascular smooth muscle cells.
Topics: Animals; Cell Division; Culture Media; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Muscle, Smooth, Vascular; Rabbits; Stimulation, Chemical; Thymidine; Verapamil | 1985 |
On the role of cyclic nucleotides in the regulation of cardiac contractility and glycolysis during hypoxia.
Topics: Animals; Cyclic AMP; Cyclic GMP; Glycolysis; Hypoxia; Lactates; Lactic Acid; Male; Myocardial Contraction; Nitroprusside; Norepinephrine; Rats; Rats, Inbred Strains; Verapamil | 1981 |
Protection of hypoxic myocardium by intracoronary administration of verapamil in open-chest dogs.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Hemodynamics; Lactates; Lactic Acid; Myocardial Contraction; Myocardial Infarction; Myocardium; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Verapamil | 1984 |
Improvement of the metabolic and energetic situation of ischemically stressed myocardium by verapamil after experimental coronary artery occlusion.
Topics: Animals; Coronary Disease; Coronary Vessels; Dogs; Energy Metabolism; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Phosphates; Potassium; Verapamil | 1983 |
Comparison of two calcium antagonists, verapamil and fendiline, in an experimental model of myocardial ischaemia mimicking classical angina on effort.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Disease; Dogs; Electrocardiography; Female; Fendiline; Hemodynamics; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Phenethylamines; Vascular Resistance; Verapamil | 1983 |
Protective effect of coenzyme Q10 on cultured skeletal muscle cell injury induced by continuous electric field stimulation.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Cells, Cultured; Coenzymes; Electric Stimulation; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Wistar; Ubiquinone; Verapamil | 1995 |
Mutagenesis by 9-aminoacridine in Salmonella typhimurium: inhibition by glucose and other PTS class A carbon sources.
Topics: Aminacrine; Arabinose; Deoxyglucose; Glucose; Glycerol; Lactates; Lactic Acid; Methylglucosides; Mutagenesis; Phosphoenolpyruvate Sugar Phosphotransferase System; Salmonella typhimurium; Verapamil | 1994 |
Insulin is a superior antidote for cardiovascular toxicity induced by verapamil in the anesthetized canine.
Topics: Anesthesia; Animals; Antidotes; Blood Glucose; Cardiovascular Diseases; Disease Models, Animal; Dogs; Electrolytes; Epinephrine; Female; Glucagon; Heart; Hemodynamics; Insulin; Lactates; Lactic Acid; Male; Reproducibility of Results; Verapamil | 1993 |
Effect of benidipine hydrochloride (KW-3049), on cerebral ischemia induced by bilateral occlusion of the common carotid arteries in rats.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Brain; Brain Chemistry; Brain Ischemia; Calcium Channel Blockers; Carotid Artery, Common; Dihydropyridines; Lactates; Lactic Acid; Male; Nicardipine; Nifedipine; Phosphocreatine; Potassium; Rats; Rats, Wistar; Sodium; Verapamil | 1993 |
Atrial contractile dysfunction after short-term atrial fibrillation is reduced by verapamil but increased by BAY K8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Atrial Fibrillation; Calcium Channel Agonists; Female; Heart Atria; Lactates; Lactic Acid; Male; Myocardial Contraction; Phosphocreatine; Swine; Verapamil | 1996 |
Myocardial metabolism during graded intraportal verapamil infusion in awake dogs.
Topics: Animals; Carbohydrate Metabolism; Dogs; Female; Heart; Insulin; Insulin Resistance; Lactic Acid; Male; Myocardium; Verapamil | 1996 |
Insulin improves heart function and metabolism during non-ischemic cardiogenic shock in awake canines.
Topics: Animals; Calcium Channel Blockers; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycerol; Insulin; Lactic Acid; Male; Myocardium; Random Allocation; Shock, Cardiogenic; Triglycerides; Vasoconstrictor Agents; Ventricular Function, Left; Verapamil | 1997 |
Temporal differences in actions of calcium channel blockers on K+ accumulation, cardiac function, and high-energy phosphate levels in ischemic guinea pig hearts.
Topics: Acidosis; Adenosine Triphosphate; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Extracellular Space; Guinea Pigs; Heart; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Nifedipine; Phosphocreatine; Potassium; Time Factors; Verapamil | 1999 |
Effect of polymer/basic drug interactions on the two-stage diffusion-controlled release from a poly(L-lactic acid) matrix.
Topics: Biocompatible Materials; Chlorpheniramine; Crystallization; Delayed-Action Preparations; Diffusion; Diltiazem; Drug Interactions; Kinetics; Lactic Acid; Papaverine; Polyesters; Polymers; Verapamil; Water; X-Ray Diffraction | 1999 |
The rate of P-glycoprotein activation depends on the metabolic state of the cell.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biosensing Techniques; Cell Culture Techniques; Cell Membrane; Culture Media, Conditioned; Enzyme Activation; Extracellular Space; Humans; Hydrogen-Ion Concentration; Lactic Acid; LLC-PK1 Cells; Mice; Mice, Knockout; NIH 3T3 Cells; Swine; Transfection; Verapamil | 2004 |
Susceptibility of nanoparticle-encapsulated paclitaxel to P-glycoprotein-mediated drug efflux.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Time Factors; Verapamil | 2006 |
PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride: systematic study of particle size and drug entrapment efficiency.
Topics: Chemistry, Pharmaceutical; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sodium Chloride; Verapamil; Vincristine | 2008 |
Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2009 |
Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Fluorouracil; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2010 |
Reversal of doxorubicin-resistance by multifunctional nanoparticles in MCF-7/ADR cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytoplasmic Granules; Cytosol; Doxorubicin; Drug Carriers; Drug Combinations; Drug Resistance, Neoplasm; Female; Fluoresceins; Fluorescent Dyes; Humans; Lactic Acid; Light; Molecular Structure; Nanoparticles; Particle Size; Photochemotherapy; Photosensitizing Agents; Polyesters; Polyethylene Glycols; Polymers; Porphyrins; Verapamil; Vitamin E | 2011 |
Metabolic flux analysis gives an insight on verapamil induced changes in central metabolism of HL-1 cells.
Topics: Alanine; Animals; Calcium Channel Blockers; Carbon Isotopes; Cell Growth Processes; Cell Line; Cell Line, Tumor; Culture Media, Serum-Free; Glucose; Glutamic Acid; Glutamine; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Metabolome; Mice; Myocytes, Cardiac; Oxygen; Verapamil | 2011 |
Linear delivery of verapamil via nanofibrous sheet-based system.
Topics: Anti-Arrhythmia Agents; Delayed-Action Preparations; Diffusion; Kinetics; Lactic Acid; Nanofibers; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Verapamil | 2012 |
cRGD-functionalized polymeric magnetic nanoparticles as a dual-drug delivery system for safe targeted cancer therapy.
Topics: Angiogenesis Inhibitors; Animals; Anti-Arrhythmia Agents; Cell Survival; Doxorubicin; Drug Carriers; Drug Combinations; Drug Delivery Systems; Electrocardiography; Hep G2 Cells; Humans; Lactic Acid; Magnetite Nanoparticles; Male; Mice; Mice, Inbred BALB C; Particle Size; Peptides, Cyclic; Pilot Projects; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sarcoma, Experimental; Solubility; Surface Properties; Tissue Distribution; Verapamil | 2013 |
Dual agent loaded PLGA nanoparticles enhanced antitumor activity in a multidrug-resistant breast tumor eenograft model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Transplantation, Heterologous; Verapamil; Vincristine | 2014 |
Contractile function assessment by intraventricular balloon alters the ability of regional ischaemia to evoke ventricular fibrillation.
Topics: Animals; Cardiac Catheters; Electrocardiography; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Phosphorus; Rats; Ventricular Fibrillation; Ventricular Function, Left; Verapamil | 2016 |
Transport of digoxin-loaded polymeric nanoparticles across BeWo cells, an in vitro model of human placental trophoblast.
Topics: Cell Line; Cell Survival; Digoxin; Female; Humans; Lactic Acid; Models, Biological; Nanoparticles; Placenta; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pregnancy; Trophoblasts; Verapamil | 2015 |
Nanoparticle-based delivery of carbamazepine: A promising approach for the treatment of refractory epilepsy.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistant Epilepsy; Electrocorticography; Isoniazid; Lactic Acid; Male; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Verapamil | 2018 |
Ultrahigh verapamil-loaded controlled release polymeric beads using superamphiphobic substrate: D-optimal statistical design, in vitro and in vivo performance.
Topics: Acrylic Resins; Animals; Delayed-Action Preparations; Drug Liberation; Lactic Acid; Male; Microspheres; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Verapamil | 2018 |