lactic acid and valproic acid

lactic acid has been researched along with valproic acid in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19907 (29.17)18.7374
1990's3 (12.50)18.2507
2000's7 (29.17)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Bovell, M; Chung, T; Leake, J; MacMillan, V1
Baverel, G; Martin, G; Michoudet, C1
Alberti, KG; Dick, DJ; Sherratt, HS; Turnbull, DM; Wilson, L1
Breningstall, GN1
Gibson, KM; Nyhan, WL; Pattarelli, PP1
Gougoux, A; Lopez-Novoa, JM; Rengel-Aranda, M; Vinay, P1
Akiyama, T; Ishikawa, T; Kanayama, M; Morishita, H; Sugiyama, N; Wada, Y1
Bolaños, JP; Medina, JM2
Bennett, JA; Keck, PE; McElroy, SL; Taylor, VE; Tugrul, KC1
Amamou, M; Ben Salah, N; Brahmi, N; Hédhili, A; Thabet, H1
Moore, RE; Paul, VJ; Williams, PG; Yoshida, WY1
Koyabu, N; Nakamura, H; Nakano, H; Ohtani, H; Satoh, S; Sawada, Y; Tsukimori, K; Ushigome, F1
Rogowska, W; Semczuk, M; Semczuk-Sikora, A1
Dager, SR; Demopulos, C; Dunner, DL; Friedman, SD; Hirashima, F; Lyoo, IK; Parow, A; Renshaw, PF; Stoll, AL1
Baverel, G; Gauthier, C; Martin, G; Michoudet, C; Vittorelli, A1
Abbott, FS; Bale, JF; Chang, TK; Garg, UC; Heese, BA; Kennedy, MJ; Leeder, JS; Pearce, RE; Price, KE; Smith, LD; Sullivan, JE; Ward, RM1
Chatterjee, R; Das, S; Guha, G; Hasmi, MA; Joardar, S1
Dargatz, H; Fahr, A; Heinzel, T; Hennig, D; Imhof, D; Kostenis, E; Schubert, S; Schubert, US1
de Theije, CG; Garssen, J; Knol, J; Kraneveld, AD; Lambert, J; Oozeer, R; Ramadan, M; van Eijndthoven, T; Wopereis, H1
Creed, KE; Dunton, E; Howell, JM; Quinlivan, R; Sewry, C1
Abu Sitta, E; Gaddam, M; Kanzy, A; Velagapudi, RK1

Trials

1 trial(s) available for lactic acid and valproic acid

ArticleYear
Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder.
    Biological psychiatry, 2004, Sep-01, Volume: 56, Issue:5

    Topics: Adult; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Brain Mapping; Case-Control Studies; Echo-Planar Imaging; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Valproic Acid

2004

Other Studies

23 other study(ies) available for lactic acid and valproic acid

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
The effect of valproic acid on the 5-hydroxyindoleacetic, homovanillic and lactic acid levels of cerebrospinal fluid.
    Brain research, 1987, Sep-15, Volume: 420, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Chlorpromazine; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Lactates; Lactic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Valproic Acid

1987
Stimulation of glutamine metabolism by the antiepileptic drug, sodium valproate, in isolated dog kidney tubules.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: Alanine; Ammonia; Animals; Aspartic Acid; Dogs; Female; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Kidney Tubules; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Valproic Acid

1989
Valproate causes metabolic disturbance in normal man.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:4

    Topics: Acetoacetates; Administration, Oral; Blood Glucose; Chemical and Drug Induced Liver Injury; Humans; Injections, Intravenous; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sodium Oxybate; Valproic Acid

1986
Valproate and lactate/pyruvate interactions.
    Neurology, 1987, Volume: 37, Issue:10

    Topics: Humans; Infant; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Valproic Acid

1987
Oxidation of [U-14C]succinic semialdehyde in cultured human lymphoblasts: measurement of residual succinic semialdehyde dehydrogenase activity in 11 patients with 4-hydroxybutyric aciduria.
    Pediatric research, 1988, Volume: 24, Issue:4

    Topics: Aldehyde Oxidoreductases; Carbon Dioxide; Cells, Cultured; Child; Child, Preschool; Female; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Infant; Kinetics; Lactates; Lactic Acid; Lymphocytes; Male; Malonates; Oxidation-Reduction; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase; Succinates; Succinic Acid; Valproic Acid

1988
Effect of valproate on renal metabolism in the intact dog.
    Kidney international, 1988, Volume: 34, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Ammonia; Animals; Biological Transport; Dogs; Kidney; Kidney Tubules; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Valproic Acid

1988
[Effects of valproate on mitochondrial function in epileptic patients].
    No to hattatsu = Brain and development, 1985, Volume: 17, Issue:6

    Topics: Adolescent; Ammonia; Carnitine; Child; Child, Preschool; Epilepsy; Humans; Lactates; Lactic Acid; Mitochondria; Valproic Acid

1985
Inhibition of neonatal brain fuel utilization by valproate and E-delta 2-valproate is not a consequence of the stimulation of the gamma-aminobutyric acid shunt.
    Life sciences, 1994, Volume: 55, Issue:20

    Topics: Animals; Animals, Newborn; Brain; Energy Metabolism; Fatty Acids, Monounsaturated; gamma-Aminobutyric Acid; Lactates; Lactic Acid; Rats; Rats, Wistar; Valproic Acid

1994
Effect of valproate on lipogenesis in neonatal rat brain.
    Biochemical pharmacology, 1993, Mar-24, Volume: 45, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Brain Chemistry; Female; Hydroxybutyrates; Lactates; Lactic Acid; Lipids; Male; Phospholipids; Rats; Rats, Wistar; Sterols; Valproic Acid

1993
Valproate treatment of panic disorder and lactate-induced panic attacks.
    Biological psychiatry, 1993, Apr-01, Volume: 33, Issue:7

    Topics: Adult; Arousal; Female; Humans; Lactates; Lactic Acid; Male; Panic; Panic Disorder; Personality Inventory; Valproic Acid

1993
Hyperlactatemia and hyperammonemia as secondary effects of valproic acid poisoning.
    The American journal of emergency medicine, 2000, Volume: 18, Issue:4

    Topics: Adolescent; Ammonia; Fatal Outcome; Female; Humans; Lactic Acid; Suicide; Valproic Acid

2000
Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium Lyngbya confervoides.
    Journal of natural products, 2002, Volume: 65, Issue:1

    Topics: Antineoplastic Agents; Chromatography; Cyanobacteria; Depsipeptides; Humans; Hydrolysis; Inhibitory Concentration 50; KB Cells; Lactic Acid; Micronesia; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic; Stereoisomerism; Valproic Acid

2002
Proton gradient-dependent transport of valproic acid in human placental brush-border membrane vesicles.
    Pharmaceutical research, 2002, Volume: 19, Issue:2

    Topics: Adult; Algorithms; Anticonvulsants; Biological Transport, Active; Fatty Acids; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lactic Acid; Membranes; Microvilli; Placenta; Pregnancy; Reproducibility of Results; Valproic Acid

2002
[Influence of valproic acid (depakine I.V.) on human placenta metabolism--experimental model].
    Ginekologia polska, 2003, Volume: 74, Issue:8

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Blood Glucose; Embryo, Mammalian; Embryonic and Fetal Development; Epilepsy; Female; Humans; In Vitro Techniques; Lactic Acid; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications; Valproic Acid

2003
Characteristics of glutamine metabolism in human precision-cut kidney slices: a 13C-NMR study.
    The Biochemical journal, 2005, May-01, Volume: 387, Issue:Pt 3

    Topics: Ammonia; Carbon Isotopes; Dose-Response Relationship, Drug; Glucose; Glutamine; Humans; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Valproic Acid

2005
Effects of valproic acid on organic acid metabolism in children: a metabolic profiling study.
    Clinical pharmacology and therapeutics, 2011, Volume: 89, Issue:6

    Topics: Adolescent; Age Factors; Carboxylic Acids; Child; Child, Preschool; Female; Humans; Infant; Lactic Acid; Male; Metabolome; Principal Component Analysis; Retrospective Studies; Treatment Outcome; Valproic Acid

2011
Unilateral basal-ganglia involvement likely due to valproate-induced hyperammonemic encephalopathy.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2012, Volume: 33, Issue:4

    Topics: Anticonvulsants; Basal Ganglia; Brain Diseases; Child, Preschool; Diffusion Magnetic Resonance Imaging; Functional Laterality; Humans; Hyperammonemia; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Seizures; Valproic Acid

2012
Novel insights into appropriate encapsulation methods for bioactive compounds into polymers: a study with peptides and HDAC inhibitors.
    Macromolecular bioscience, 2014, Volume: 14, Issue:1

    Topics: Acetylation; Angiotensin II; Carbazoles; Dextrans; Drug Carriers; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lactic Acid; Liposomes; Nanoparticles; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sirtuin 1; Valproic Acid

2014
Altered gut microbiota and activity in a murine model of autism spectrum disorders.
    Brain, behavior, and immunity, 2014, Volume: 37

    Topics: Acetic Acid; Animals; Butyric Acid; Child Development Disorders, Pervasive; Disease Models, Animal; Female; Intestine, Large; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Microbiota; Sex Factors; Valproic Acid

2014
Investigating sodium valproate as a treatment for McArdle disease in sheep.
    Neuromuscular disorders : NMD, 2015, Volume: 25, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Calcium; Creatine Kinase; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Glycogen Storage Disease Type V; Lactic Acid; Locomotion; Muscle Fibers, Skeletal; Phosphorylases; Sheep; Time Factors; Valproic Acid

2015
Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning?
    BMJ case reports, 2017, Oct-15, Volume: 2017

    Topics: Acid-Base Equilibrium; Acidosis; Anticonvulsants; Brain Diseases; Calcium Oxalate; Cognitive Dysfunction; Diagnosis, Differential; Epilepsy; Ethylene Glycol; Humans; Lactic Acid; Male; Medication Adherence; Middle Aged; Osmolar Concentration; Urolithiasis; Valproic Acid

2017