lactic acid has been researched along with uracil in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 11 (61.11) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Asano, M; Fukuzaki, H; Imai, K; KumaKura, M; Mashimo, T; Yamanaka, H; Yoshida, M; Yuasa, H | 1 |
| Arnold, RR; Brewer, M; Champion, WJ; Gauthier, JJ; Russell, JE | 1 |
| Arellano, M; Malet-Martino, M; Martino, R; Spector, T | 1 |
| DRISCOLL, CA; MILLER, CS; WRIGHT, LD | 1 |
| Franzetti, L; Hidalgo, A; Pompei, C; Rossi, M | 1 |
| Akerlund, HE; Andersen, G; Björnberg, O; Compagno, C; Gojković, Z; Hofer, A; Merico, AM; Moritz, T; Møller, K; Piskur, J; Polakova, S; Pynyaha, Y; Rasmussen, A; Sandrini, MP | 1 |
| Halestrap, AP; Manoharan, C; Murray, CM; Ovens, MJ; Wilson, MC | 1 |
| Chiche, J; Critchlow, SE; Ilc, K; Ilk, K; Le Floch, R; Marchiq, I; Murray, CM; Naiken, T; Pouysségur, J; Roux, D; Simon, MP | 1 |
| Bouzin, C; Draoui, N; Feron, O; Riant, O; Schicke, O; Seront, E; Sonveaux, P | 1 |
| Halestrap, AP; Nancolas, B; Sessions, RB | 1 |
| Antonov, EN; Butnaru, DV; Istranova, EV; Minaeva, SA; Popov, VK; Vinarov, AZ | 1 |
| Ahn, SM; Chang, WJ; Cho, JH; Jung, KS; Kang, WK; Kim, HS; Kim, KM; Kim, ST; Kim, SY; Lee, I; Lee, J; Lee, JY; Lee, S; Lim, HY; Lim, SH; Park, JO; Park, SH; Park, YS; Song, HN; Yoo, KH | 1 |
| Becker, HM; Deitmer, JW; Forero-Quintero, LS | 1 |
| Bastien, E; Becker, HM; Chaltin, P; Corbet, C; Doix, B; Draoui, N; Feron, O; Jordan, BF; Marchand, A; Mignion, L; Riant, O; Schakman, O; Vanherck, JC | 1 |
| Eichner, R; Girardi, E; Hashimoto, M; Superti-Furga, G | 1 |
| Guan, X; Morris, ME; Rodriguez-Cruz, V | 1 |
| Eliopoulos, E; Papakonstantinou, E; Thireou, T; Vlachakis, D; Vlachoyiannopoulos, PG | 1 |
1 trial(s) available for lactic acid and uracil
| Article | Year |
|---|---|
Fundamental study on the implantable LH-RH agonist/polymer and its use in a randomized trial for prostate cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Implants; Drug Screening Assays, Antitumor; Humans; Lactates; Lactic Acid; Male; Polyesters; Polymers; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Receptors, LHRH; Tegafur; Uracil | 1990 |
17 other study(ies) available for lactic acid and uracil
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Bactericidal activity of human lactoferrin: differentiation from the stasis of iron deprivation.
Topics: Glucose; Humans; Iron; Lactates; Lactic Acid; Lactoferrin; Lactoglobulins; Lysine; Streptococcus mutans; Thymidine; Uracil | 1982 |
5-Ethynyluracil (GW776): effects on the formation of the toxic catabolites of 5-fluorouracil, fluoroacetate and fluorohydroxypropionic acid in the isolated perfused rat liver model.
Topics: Animals; Bile; Enzyme Inhibitors; Fluoroacetates; Fluorouracil; In Vitro Techniques; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Uracil | 1997 |
Inactivity of dihydrouracil and ureidopropionic acid as pyrimidine precursors for lactic acid bacteria.
Topics: Lactic Acid; Lactobacillus; Lipid Metabolism; Propionates; Pyrimidines; Uracil | 1954 |
Chemical markers for the evaluation of raw material hygienic quality in egg products.
Topics: Acetic Acid; Animals; Colony Count, Microbial; Eggs; Food Contamination; Food Microbiology; Humans; Hygiene; Lactic Acid; Temperature; Time Factors; Uracil | 2008 |
A second pathway to degrade pyrimidine nucleic acid precursors in eukaryotes.
Topics: Eukaryotic Cells; Fungal Proteins; Lactic Acid; Molecular Structure; Mutagenesis, Site-Directed; Nucleic Acid Precursors; Oxygen; Pentosyltransferases; Pyrimidines; Saccharomyces; Uracil; Urea; Uridine | 2008 |
The inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary protein.
Topics: Animals; Basigin; Erythrocytes; Glycoproteins; Kinetics; Lactic Acid; Membrane Proteins; Monocarboxylic Acid Transporters; Mutant Proteins; Oocytes; Rabbits; Rats; Recombinant Proteins; Symporters; Thiophenes; Uracil; Xenopus laevis; Xenopus Proteins | 2010 |
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.
Topics: Basigin; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; DNA Primers; Flow Cytometry; Fluorescent Antibody Technique; Gene Knockout Techniques; Gene Silencing; Glycolysis; Humans; Immunohistochemistry; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Oxygen Consumption; Protein Subunits; Symporters; Thiophenes; Uracil | 2011 |
Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux.
Topics: Animals; Breast Neoplasms; Colorectal Neoplasms; Coumarins; Female; HCT116 Cells; Humans; Lactic Acid; MCF-7 Cells; Mice; Neoplasm Recurrence, Local; Prognosis; Thiophenes; Uracil | 2014 |
Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.
Topics: Amino Acid Substitution; Amino Acids; Animals; Binding Sites; Biological Transport; Female; Gene Expression; Humans; Lactic Acid; Mice; Molecular Docking Simulation; Monocarboxylic Acid Transporters; Muscle Proteins; Mutagenesis, Site-Directed; Oocytes; Protein Binding; Rats; Recombinant Proteins; Symporters; Thiophenes; Uracil; Xenopus laevis | 2015 |
[Kinetics of methyluracil release from bioresorbable polymeric carriers].
Topics: Adjuvants, Immunologic; Biodegradable Plastics; Drug Carriers; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Time Factors; Uracil | 2015 |
MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Female; Humans; Lactic Acid; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Monocarboxylic Acid Transporters; Muscle Proteins; Peritoneal Neoplasms; RNA Interference; RNA, Small Interfering; Stomach Neoplasms; Symporters; Thiophenes; Up-Regulation; Uracil; Xenograft Model Antitumor Assays | 2016 |
Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters.
Topics: 3-Hydroxybutyric Acid; Animals; Astrocytes; Brain; Diet, Ketogenic; Disease Models, Animal; Epilepsy; Gene Expression Regulation; Glycolysis; Ketone Bodies; Lactic Acid; Mice; Mice, Inbred C57BL; Microtomy; Monocarboxylic Acid Transporters; Neurons; Primary Cell Culture; Seizures; Signal Transduction; Symporters; Thiophenes; Tissue Culture Techniques; Uracil | 2017 |
Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Female; Gene Silencing; Glucose; Glycolysis; Humans; Ion Transport; Lactic Acid; Male; MCF-7 Cells; Mice; Mice, Inbred C57BL; Mitochondria; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasm Transplantation; Oxygen; Pyruvic Acid; Radiation-Sensitizing Agents; Rats; RNA, Small Interfering; Symporters; Thiophenes; Uracil; Xenopus laevis | 2018 |
Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay.
Topics: Biological Assay; Excitatory Amino Acid Transporter 2; Formates; Glutamate Plasma Membrane Transport Proteins; Heating; HEK293 Cells; Humans; Lactic Acid; Ligands; Monocarboxylic Acid Transporters; Protein Binding; Protein Stability; Pyrimidinones; Thiophenes; Uracil | 2018 |
Cellular Uptake of MCT1 Inhibitors AR-C155858 and AZD3965 and Their Effects on MCT-Mediated Transport of L-Lactate in Murine 4T1 Breast Tumor Cancer Cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Coumaric Acids; Drug Screening Assays, Antitumor; Female; Humans; Hydrogen-Ion Concentration; Lactic Acid; Mice; Monocarboxylic Acid Transporters; Pyrimidinones; Symporters; Thiophenes; Uracil | 2019 |
A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4).
Topics: Animals; Antineoplastic Agents; Binding Sites; Biological Transport; Drug Design; Glycolysis; Humans; Lactic Acid; Molecular Docking Simulation; Monocarboxylic Acid Transporters; Muscle Proteins; Phloretin; Phylogeny; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Isoforms; Pyrimidinones; Quercetin; Reserpine; Structural Homology, Protein; Substrate Specificity; Thiophenes; Uracil | 2021 |