lactic acid has been researched along with thiazoles in 113 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.77) | 18.7374 |
| 1990's | 8 (7.08) | 18.2507 |
| 2000's | 35 (30.97) | 29.6817 |
| 2010's | 65 (57.52) | 24.3611 |
| 2020's | 3 (2.65) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, T; Horikoshi, H; Ushiyama, I; Yoshioka, S; Yoshioka, T | 1 |
| Inglot, AD; Wolna, E | 1 |
| Bähr, M; Bock, M; Eckel, J; Kiehn, R; Spelleken, M; von Holtey, M | 1 |
| Abbott, NJ; Chan, MW; Rist, RJ; Romero, IA | 1 |
| Abbott, NJ; Aleshaiker, A; Rist, RJ; Romero, IA | 1 |
| Kliewer, SA; Lehmann, JM; Lenhard, JM; Paulik, MA; Plunket, KD; Weiel, JE | 1 |
| Adams, MD; Judd, RL; Raman, P | 1 |
| Kissel, T; Li, Y; Zange, R | 1 |
| Bringer-Meyer, S; Galinina, N; Kalnenieks, U; Poole, RK | 1 |
| Matsuda, H; Matsuoka, J; Tanaka, N; Yagi, T; Yamamura, H | 1 |
| Abe, H; Kusano, S | 1 |
| Covián, R; Jasso-Chávez, R; Moreno-Sánchez, R; Pacheco-Moisés, F; Rodríguez-Enríquez, S; Torres-Márquez, ME | 1 |
| Cinatl, J; Kreuter, J; Langer, K; Matousek, J; Michaelis, M; Schwabe, D; Slavik, T; Vogel, JU | 1 |
| Lee, KH; Oh, JE; Park, TG; Yoo, HS | 1 |
| Bal-Price, A; Brown, GC | 1 |
| Brindley, DN; Davidge, ST; Delrat, P; Jochemsen, R; Kelly, SE; O'Brien, SF; Pégorier, JP; Ravel, D; Russell, JC | 1 |
| Judd, RL; Raman, P | 1 |
| Cai, K; Cui, Y; Gao, L; Li, X; Qing, T; Xie, H; Yang, Z; Yao, K | 1 |
| Berrebi-Bertrand, I; Bril, A; Buckingham, RE; Delerive, P; Khandoudi, N; Staels, B | 1 |
| Cai, K; Li, F; Li, X; Liu, W; Xie, H; Yang, Z; Yao, K | 1 |
| Battarbee, H; Coates, G; McCarthy, K; Routh, R; Su, G; Welbourne, T | 1 |
| Corton, JC; Dohm, GL; Houmard, JA; Kraus, WE; Lang, DB; Li, S; MacLean, PS; Muoio, DM; Way, JM; Winegar, DA | 1 |
| Cai, K; Hou, X; Hou, Y; Li, X; Wang, Y; Xie, H; Yang, Z; Yao, K | 1 |
| Brown, SC; Coates, M; Griffith, LG; Landeen, LK; Monkhouse, DC; Palazzolo, R; Ratcliffe, A; Riley, SL; Sherwood, JK | 1 |
| Gao, C; Gong, Y; Ji, J; Ma, Z; Shen, J | 1 |
| Bogónez, E; Bovolenta, P; del Arco, A; Kobayashi, K; Martínez-Morales, JR; Martínez-Serrano, A; Pardo, B; Ramos, M; Saheki, T; Satrústegui, J; Yasuda, T | 1 |
| Gao, C; Gong, Y; Ma, Z; Shen, J | 1 |
| Cui, YL; Liu, WG; Ma, DM; Qi, AD; Wang, H; Wang, XH; Yao, KD | 1 |
| Cho, SH; Kang, SG; Kim, ES; Lee, JH; Oh, SH | 1 |
| Adriaensen, J; Borghys, H; Brewster, ME; Bruining, M; Chun, I; Decorte, A; Heymans, K; Kataria, R; Li, Y; Meert, T; Peeters, J; Rosenblatt, J; Van Remoortere, M; Verreck, G; Zhang, Q | 1 |
| Chan-Park, MB; Zhu, AP | 1 |
| Aberra, M; Aten, J; Deira, G; Dragt, CA; Krediet, RT; van Westrhenen, R | 1 |
| Coe, I; Eguchi, M; Palanivel, R; Shuralyova, I; Sweeney, G | 1 |
| Huang, LJ; Li, CH; Lu, ZM; Ma, ZB; Yu, DQ | 1 |
| Singh, J; Singh, S | 1 |
| Dong, Y; Feng, SS | 1 |
| Garreau, H; Garric, X; Molès, JP; Vert, M | 1 |
| Antimisiaris, SG; Dracopoulos, V; Fadda, AM; Manca, ML; Mourtas, S | 1 |
| Cheng, G; Chung, SJ; Cui, F; Kim, DD; Kim, IW; Shim, CK; Shim, WS; Yang, R; Yang, SG | 1 |
| Baker, DJ; Constantin, D; Constantin-Teodosiu, D; Greenhaff, PL | 1 |
| Chen, X; Jing, X; Wang, Z; Xu, X | 1 |
| Lai, JY; Lee, IC; Lee, YT; Young, TH; Yu, BY | 1 |
| Cheng, G; Chung, SJ; Cui, FD; Han, X; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Yang, R | 1 |
| Anitha, P; Feng, SS; Gan, CW; Mei, L; Zhou, W | 1 |
| Cai, Z; Cui, FY; Gong, DQ; He, G; Hou, SX; Lei, XJ; Song, XR; Wei, YQ; Xiong, SJ; Zheng, Y | 1 |
| Barcia, E; Fernández-Carballido, A; Montejo, C; Negro, S | 1 |
| Bolden, G; Chinta, DM; Dash, S; Graves, RA; Hazari, S; Kishore, V; Mandal, TK; Pamujula, S | 1 |
| He, G; He, ZY; Hou, SX; Li, JM; Li, SZ; Luo, X; Luo, YF; Song, XR; Wei, YQ; Yang, L; Yu, S; Zheng, Y | 1 |
| Ding, B; Ding, X; Fan, W; Gao, J; Gao, S; Hou, X; Wang, X; Wu, X; Zhang, M; Zhang, W; Zhu, Q | 1 |
| Li, ML; Li, Y; Liu, JS; Wang, J; Yang, P; Zhao, ZH; Zheng, W | 1 |
| Feng, SS; Kulkarni, SA | 1 |
| Michinaka, Y; Mitragotri, S | 1 |
| Cheyne, RW; McLaughlin, A; Smith, TA; Trembleau, L | 1 |
| Chiang Boey, FY; Huang, CL; Kumar, S; Loo, JS; Steele, TW; Venkatraman, SS; Widjaja, E | 1 |
| Chung, S; Gamcsik, MP; King, MW | 1 |
| Criscione, JM; Jun, L; Lavik, EB; Robinson, R; Tsai, JC; Viviano, SR; Williams, CA | 1 |
| Cheyne, RW; Smith, TA | 1 |
| Gao, H; Jiang, X; Lu, W; Pang, Z; Yin, Q; Yu, Y | 1 |
| Chen, J; Feng, C; Jiang, X; Liu, Q; Shao, X; Shen, Y; Zhang, C; Zhang, Q | 1 |
| Ding, J; He, Y; Pan, Z; Peng, R; Yan, C; Zhao, Y | 1 |
| Inagi, T; Makino, K; Suzuki, K; Terada, H; Terashima, H; Tomoda, K | 1 |
| Gang, SS; Hariharapura, RC; Jagani, HV; Josyula, VR; Palanimuthu, VR | 1 |
| Chung, SP; Diem, TH; El Sayed, SM; El-Magd, RM; Fukui, K; Kagami, S; Sakai, T; Shishido, Y; Watanabe, H | 1 |
| Dogan, AL; Esendagli, G; Gönül, N; Guc, D; Hasçiçek, C; Şengel-Türk, CT | 1 |
| Azevedo-Silva, J; Baltazar, F; Casal, M; Ko, YH; Moreira, R; Pacheco, A; Pedersen, PL; Pedro, M; Pinheiro, C; Preto, A; Queirós, O | 1 |
| Borges, F; Cordeiro da Silva, A; Costa Lima, S; Garrido, J; Kong Thoo Lin, P; Rodrigues, V | 1 |
| Jeon, SY; Park, JS; Park, KH; Woo, DG; Yang, HN | 1 |
| Amarnath, K; Jeevitha, D | 1 |
| Bobermin, LD; de Souza, DF; Fontoura, JB; Gonçalves, CA; Hansen, F; Hoefel, AL; Leite, MC; Perry, ML; Silveira, Sda L; Tramontina, AC | 1 |
| Guo, D; Hou, L; Mao, P; Mo, L; Xiao, X; Yang, X | 1 |
| Jin, Y; Li, B; Ma, W; Xu, A; Xu, G; Yao, M; Ying, J | 1 |
| Arduino, DM; Cardoso, SM; Esteves, AR; Januario, C; Martins-Branco, D; Oliveira, CR; Santos, D; Swerdlow, RH | 1 |
| Cheng, L; Hsia, RC; Melo, MA; Rodrigues, LK; Weir, MD; Xu, HH | 1 |
| Ahmed, TA; Hussain, MD; Ibrahim, HM; Kaseem, AA; Nutan, MT; Rahman, Z; Samy, AM | 1 |
| About, I; Fessi, H; Jeanneau, C; Kalaji, N; Mathieu, S; Sheibat-Othman, N | 1 |
| Hirota, K; Kawamoto, T; Makino, K; Nakajima, T; Terada, H | 1 |
| Liu, C; Liu, X; Lu, W; Wei, G; Xie, C; Zhang, W | 1 |
| Du, X; Fu, D; Huang, C; Liu, Y; Pei, D; Sun, H | 1 |
| Huang, L; Liu, T; Mei, L; Ouyang, C; Tao, W; Wang, Z; Xiong, Q; Zeng, X | 1 |
| Chereddy, KK; Coco, R; des Rieux, A; Memvanga, PB; Préat, V; Ucakar, B; Vandermeulen, G | 1 |
| Avula, MN; Grainger, DW; McGill, LD; Rao, AN; Solzbacher, F | 1 |
| Chandran, P; Gupta, N; Koyakutty, M; Malarvizhi, GL; Nair, S; Ramachandran, R; Retnakumari, AP | 1 |
| Alexis, F; Grimes, SW; Lewis, RL; Moore, TL | 1 |
| Barnes, M; Bousba, S; Cameron, J; Davenport, R; Dickson, L; Grosse, J; Harrison, D; Leveridge, M; Mack, S; Matsui, J; Ogawa, K; Parmar, A; Parton, L; Sakurai, T; Stafford, S; Sykes, A | 1 |
| Chen, H; Chen, J; Feng, X; Gao, X; Hu, Q; Huang, M; Jiang, D; Jiang, X; Kang, T; Pang, Z; Song, Q; Yao, L; Zhang, X | 1 |
| Benjaminsen, J; Fenaroli, F; Griffiths, G; Hildahl, J; Kolstad, T; Meijer, AH; Nyström, B; Roos, N; Skjeldal, FM; Ulanova, L; van der Vaart, M; Westmoreland, D | 1 |
| Chandran, P; Gupta, N; Koyakutty, M; Malarvizhi, GL; Menon, D; Nair, S; Panikar, D; Ramachandran, R | 1 |
| Bao, X; Chu, QC; Gao, M; Guan, X; Jiang, N; Liu, KX; Tian, Y; Xu, H; Zhang, CH | 1 |
| Cormode, DP; Latourette, MT; Mallet, CL; Parys, M; Schwartz-Duval, AS; Shapiro, EM; Shuboni, DD; Swy, ER | 1 |
| Blumrich, EM; Dringen, R; Hohnholt, MC | 1 |
| Chiba, S; Chong, HC; Choong, C; Foo, S; Lee, WL; Loo, SC; Luo, B; Ng, KW; Sng, MK; Tan, NS; Tang, MB; Tong, BM; Wang, X; Wong, MT; Zhu, P | 1 |
| Astete, CE; Damann, KE; Muse, ES; Patel, NR; Sabliov, CM | 1 |
| Baneham, S; Cox, D; Kirby, BP; Moollan, A; O'Donnell, A; Ozgul, M; Pabari, RM; Ramtoola, Z | 1 |
| Du, Y; Gu, G; Liu, J; Liu, Y; Sun, X | 1 |
| Chen, C; Chen, X; Fan, Z; Fang, X; Liang, H; Pang, X; Qi, Y; Sha, X; Yu, Z | 1 |
| Aminaie, M; Aveseh, M; Nikooie, R | 1 |
| Wang, L; Xiao, H | 1 |
| Ameloot, M; Berden, M; D'Olieslaeger, L; Deville, S; Ethirajan, A; Penjweini, R | 1 |
| Keloglu, N; Sohier, J; Trimaille, T; Verrier, B | 1 |
| Chu, Q; Deng, S; Gao, M; Guan, X; Huo, X; Liu, H; Liu, K; Ma, X; Tian, Y; Xu, H | 1 |
| da Costa, TL; de A Picanço, G; de Lima, NF; de S Lino Junior, R; de S M M Alves, D; Fraga, CM; Isac, E; Vinaud, MC | 1 |
| Jia, Y; Liu, S; Liu, X; Pan, W; Tian, C; Wang, H; Wang, Y; Yan, J | 1 |
| Bhatta, RS; Gupta, A; Misra, A; Tulsankar, SL | 1 |
| Du, M; Fu, L; Fu, Y; Ge, B; Liu, J; Yan, Q; Zhang, S | 1 |
| Chang, PC; Feng, F; Lin, JH; Wang, CH; Yu, MC | 1 |
| Chen, J; Dai, HB; Luo, L; Luo, ML; Sun, D; Wang, GX; Wang, Y; Wu, Q; Wu, W; Zhong, Y | 1 |
| Costa, TL; Fraga, CM; Lima, NF; Lino-Junior, RS; Nasareth, JM; Picanço, GA; Vinaud, MC | 1 |
| Cao, W; Chen, G; Wen, L; Xie, S; Xu, Y; Zhang, L | 1 |
| An, YJ; Choi, SY; Im, JH; Jeong, BH; Kang, KW; Kim, SY; Kim, YG; Lee, JS; Park, S | 1 |
| Alves, DSMM; Costa, TL; Isac, E; Lima, NF; Lino Junior, RS; Picanço, GA; Silva, LD; Vinaud, MC | 1 |
| Bastidas, JG; da Silveira, MR; Ferreira, CA; Maurmann, N; Pranke, P | 1 |
| Duong, HD; Rhee, JI | 1 |
| Liu, J; Shi, Q; Tao, H; Xie, X; Yao, J; Zhi, H | 1 |
1 review(s) available for lactic acid and thiazoles
| Article | Year |
|---|---|
Predicting tumour response to anti-HER1 therapy using medical imaging: a literature review and in vitro study of [18F]-FDG incorporation by breast cancer cells responding to cetuximab.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cetuximab; Colony-Forming Units Assay; ErbB Receptors; Female; Fluorodeoxyglucose F18; Glucose; Hexokinase; Humans; Lactic Acid; Positron-Emission Tomography; Tetrazolium Salts; Thiazoles | 2011 |
1 trial(s) available for lactic acid and thiazoles
| Article | Year |
|---|---|
Effect of desensitising paste containing 8% arginine and calcium carbonate on biofilm formation of Streptococcus mutans in vitro.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Arginine; Bacterial Adhesion; Biofilms; Calcium Carbonate; Coloring Agents; Dental Prophylaxis; Dentifrices; Dentin; Dentin Desensitizing Agents; Fluorides; Humans; Imaging, Three-Dimensional; Lactic Acid; Microbial Viability; Microscopy, Electron, Scanning; Phosphates; Silicates; Streptococcus mutans; Tetrazolium Salts; Thiazoles; Time Factors; Young Adult | 2013 |
111 other study(ies) available for lactic acid and thiazoles
| Article | Year |
|---|---|
Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats.
Topics: Adipose Tissue; Animals; Benzopyrans; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Ketone Bodies; Lactates; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Inbred Strains; Rats, Zucker; Receptor, Insulin; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1988 |
Effects of Wratizolin on growth and metabolism of cells in vitro.
Topics: Amnion; Animals; Anti-Inflammatory Agents; Cattle; Cell Line; Cells, Cultured; Chick Embryo; DNA; Fibroblasts; Glucose; Humans; Indomethacin; Kidney; Lactates; Lactic Acid; Lymphocytes; Mice; Swine; Thiazoles; Thymidine | 1983 |
Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes.
Topics: 3-O-Methylglucose; Animals; Cells, Cultured; Chromans; Cytosol; Dose-Response Relationship, Drug; Glucose Transporter Type 1; Glucose Transporter Type 4; Heart Ventricles; Hypoglycemic Agents; Immune Sera; Immunoblotting; Isoenzymes; Lactic Acid; Male; Membrane Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone | 1996 |
Effects of energy deprivation induced by fluorocitrate in immortalised rat brain microvessel endothelial cells.
Topics: Actins; Adenosine Triphosphate; Animals; Capillary Permeability; Cell Line, Transformed; Cerebrovascular Circulation; Citrates; Cytoskeleton; Endothelium, Vascular; Energy Metabolism; Glucose; Intracellular Membranes; Lactic Acid; Microcirculation; Rats; Tetrazolium Salts; Thiazoles | 1996 |
Metabolic and permeability changes caused by thiamine deficiency in immortalized rat brain microvessel endothelial cells.
Topics: Actins; Animals; Antimetabolites; Blood Vessels; Capillary Permeability; Cell Line, Transformed; Cytoskeleton; Endothelium, Vascular; Glucose; Lactic Acid; Microcirculation; Oxidation-Reduction; Pyrithiamine; Rats; Tetrazolium Salts; Thiamine Deficiency; Thiazoles | 1997 |
Effects of troglitazone and metformin on glucose and lipid metabolism: alterations of two distinct molecular pathways.
Topics: Animals; Biological Transport; Chromans; Glucose; Hypoglycemic Agents; Lactic Acid; Lipid Metabolism; Metformin; Mice; Mice, Inbred C3H; Mitochondria; Palmitoyl Coenzyme A; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 1997 |
Comparative effects of englitazone and glyburide on gluconeogenesis and glycolysis in the isolated perfused rat liver.
Topics: Animals; Benzopyrans; Dihydroxyacetone; Fructose; Gluconeogenesis; Glucose; Glyburide; Glycerol; Glycolysis; Hypoglycemic Agents; In Vitro Techniques; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones | 1998 |
Biocompatibility testing of ABA triblock copolymers consisting of poly(L-lactic-co-glycolic acid) A blocks attached to a central poly(ethylene oxide) B block under in vitro conditions using different L929 mouse fibroblasts cell culture models.
Topics: Animals; Biocompatible Materials; Cell Survival; Cells, Cultured; Fibroblasts; Lactic Acid; Mice; Molecular Weight; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tetrazolium Salts; Thiazoles | 1998 |
Membrane D-lactate oxidase in Zymomonas mobilis: evidence for a branched respiratory chain.
Topics: Aerobiosis; Chlorpromazine; Cytochromes; Electron Transport; Lactic Acid; Methacrylates; Mixed Function Oxygenases; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxygen Consumption; Spectrophotometry; Thiazoles; Zymomonas | 1998 |
Subzero nonfreezing storage of isolated rat hepatocytes in University of Wisconsin solution.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Cell Separation; Cryopreservation; Glutathione; Hypoxia; Insulin; Lactic Acid; Liver; Male; Microscopy, Electron, Scanning; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Trypan Blue | 1999 |
Antidiabetic activity of white skinned sweet potato (Ipomoea batatas L.) in obese Zucker fatty rats.
Topics: Animals; Blood Glucose; Chromans; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hyperinsulinism; Hypoglycemic Agents; Insulin; Islets of Langerhans; Lactic Acid; Male; Plant Extracts; Rats; Rats, Zucker; Solanaceae; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Weight Gain | 2000 |
Oxidative phosphorylation supported by an alternative respiratory pathway in mitochondria from Euglena.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Cell Respiration; Enzyme Activation; Euglena; Lactic Acid; Methacrylates; Mitochondria; NADH Dehydrogenase; Oxidative Phosphorylation; Polyenes; Sodium Cyanide; Thiazoles | 2000 |
Bovine seminal ribonuclease attached to nanoparticles made of polylactic acid kills leukemia and lymphoma cell lines in vitro.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Division; Dose-Response Relationship, Drug; Drug Carriers; Endoribonucleases; Fibroblasts; Humans; Lactic Acid; Leukemia; Lymphoma; Male; Mice; Mice, Inbred ICR; Microspheres; Polyesters; Polymers; Spermatozoa; Testis; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
In vitro and in vivo anti-tumor activities of nanoparticles based on doxorubicin-PLGA conjugates.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Electrochemistry; Lactic Acid; Mice; Microscopy, Confocal; Microspheres; Neoplasm Transplantation; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tetrazolium Salts; Thiazoles; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured | 2000 |
Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Azides; Caspase Inhibitors; Caspases; Cell Respiration; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Glucose; Lactic Acid; Membrane Potentials; Methacrylates; Mitochondria; Necrosis; Nitric Oxide; Nitric Oxide Donors; Oxygen Consumption; PC12 Cells; Rats; Thiazoles | 2000 |
Beneficial insulin-sensitizing and vascular effects of S15261 in the insulin-resistant JCR:LA-cp rat.
Topics: Animals; Blood Glucose; Body Weight; Chromans; Eating; Fluorenes; Gene Expression; Glucose Tolerance Test; Glucose-6-Phosphatase; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Resistance; Lactic Acid; Lipids; Liver; Male; Mesenteric Arteries; Metformin; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphoenolpyruvate Carboxylase; Rats; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Vascular Resistance | 2000 |
Role of glucose and insulin in thiazolidinedione-induced alterations in hepatic gluconeogenesis.
Topics: Animals; Chromans; Gluconeogenesis; Glucose; Hepatocytes; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Phosphofructokinase-1; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Influence of different surface modification treatments on poly(D,L-lactic acid) with silk fibroin and their effects on the culture of osteoblast in vitro.
Topics: Alkaline Phosphatase; Animals; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Fibroins; Insect Proteins; Kinetics; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Osteoblasts; Oxygen; Polyesters; Polymers; Rats; Silk; Tetrazolium Salts; Thiazoles; Time Factors | 2002 |
Rosiglitazone, a peroxisome proliferator-activated receptor-gamma, inhibits the Jun NH(2)-terminal kinase/activating protein 1 pathway and protects the heart from ischemia/reperfusion injury.
Topics: Animals; Cardiotonic Agents; Carrier Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glucose Transporter Type 4; Hypoglycemic Agents; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lactic Acid; Male; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; Muscle Proteins; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Modulation of osteoblast function using poly(D,L-lactic acid) surfaces modified with alkylation derivative of chitosan.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Biocompatible Materials; Cell Division; Cell Survival; Cells, Cultured; Chitin; Chitosan; Coloring Agents; Kinetics; Lactic Acid; Membranes, Artificial; Microscopy, Electron, Scanning; Osteoblasts; Oxygen; Polyesters; Polymers; Rats; Skull; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2002 |
Troglitazone induces a cellular acidosis by inhibiting acid extrusion in cultured rat mesangial cells.
Topics: Acid-Base Equilibrium; Acids; Alanine; Animals; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Glomerular Mesangium; Hydrogen-Ion Concentration; Hypoglycemic Agents; Intracellular Fluid; Lactic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.
Topics: Animals; Blood Glucose; Carrier Proteins; Energy Metabolism; Fatty Acids; Fatty Acids, Nonesterified; Homeostasis; Humans; Ion Channels; Isoenzymes; Ketones; Lactic Acid; Liver Glycogen; Mice; Mice, Knockout; Mitochondrial Proteins; Muscle, Skeletal; Oxazoles; Oxidation-Reduction; Physical Conditioning, Animal; Protein Kinases; Rats; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcription Factors; Transcription, Genetic; Tyrosine; Uncoupling Protein 3 | 2002 |
Improvement of the functions of osteoblasts seeded on modified poly(D,L-lactic acid) with poly(aspartic acid).
Topics: Alkaline Phosphatase; Cell Adhesion; Cell Division; Cell Survival; Cells, Cultured; Cells, Immobilized; Chemical Phenomena; Chemistry, Physical; Humans; Lactic Acid; Materials Testing; Membranes, Artificial; Osteoblasts; Peptides; Polyesters; Polymers; Proteins; Surface Properties; Tetrazolium Salts; Thiazoles | 2002 |
A three-dimensional osteochondral composite scaffold for articular cartilage repair.
Topics: Analysis of Variance; Biocompatible Materials; Biodegradation, Environmental; Cartilage, Articular; Collagen; DNA; Glycosaminoglycans; Humans; Lactic Acid; Microscopy, Electron, Scanning; Osteoarthritis; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tetrazolium Salts; Thiazoles; Wound Healing | 2002 |
Immobilization of natural macromolecules on poly-L-lactic acid membrane surface in order to improve its cytocompatibility.
Topics: Animals; Cell Adhesion; Cell Division; Cells, Cultured; Chitin; Chitosan; Chondrocytes; Coated Materials, Biocompatible; Collagen; Gelatin; In Vitro Techniques; Lactic Acid; Macromolecular Substances; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Polymers; Polymethyl Methacrylate; Rabbits; Surface Properties; Tetrazolium Salts; Thiazoles | 2002 |
Developmental changes in the Ca2+-regulated mitochondrial aspartate-glutamate carrier aralar1 in brain and prominent expression in the spinal cord.
Topics: Amino Acid Transport Systems, Acidic; Animals; Antiporters; Blotting, Southern; Blotting, Western; Brain; Calcium; Calcium-Binding Proteins; Cell Line; Cells, Cultured; DNA, Mitochondrial; Embryo, Mammalian; Gene Expression Regulation, Developmental; Glutamic Acid; In Situ Hybridization; Lactic Acid; Malates; Membrane Transport Proteins; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Neuroglia; Neurons; Organic Anion Transporters; Phosphoric Monoester Hydrolases; Protein Isoforms; Proton-Translocating ATPases; Rats; Rats, Wistar; Spinal Cord; Stem Cells; Succinic Acid; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Distribution | 2003 |
Chondrocyte behaviors on poly-L-lactic acid (PLLA) membranes containing hydroxyl, amide or carboxyl groups.
Topics: Animals; Cell Adhesion; Cell Division; Cell Survival; Cells, Cultured; Chondrocytes; Lactic Acid; Microscopy, Atomic Force; Polyesters; Polymers; Rabbits; Tetrazolium Salts; Thiazoles | 2003 |
Biomimetic surface modification of poly(L-lactic acid) with chitosan and its effects on articular chondrocytes in vitro.
Topics: Animals; Biocompatible Materials; Bromodeoxyuridine; Cartilage, Articular; Cattle; Cell Adhesion; Cell Division; Cell Survival; Chitin; Chitosan; Chondrocytes; Collagen; Coloring Agents; DNA; Enzyme-Linked Immunosorbent Assay; Glycosaminoglycans; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Nitrogen; Polyesters; Polymers; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2003 |
Fabrication and characterization of hydrophilic poly(lactic-co-glycolic acid)/poly(vinyl alcohol) blend cell scaffolds by melt-molding particulate-leaching method.
Topics: Animals; Cells, Cultured; Chondrocytes; Coloring Agents; Dose-Response Relationship, Drug; Glycolates; Humans; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Rabbits; Surface Properties; Tensile Strength; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Engineering | 2003 |
Preparation and physicochemical characterization of biodegradable nerve guides containing the nerve growth agent sabeluzole.
Topics: Absorbable Implants; Animals; Biocompatible Materials; Body Fluids; Diffusion; Drug Implants; Drug Stability; Equipment Failure Analysis; Humans; Lactic Acid; Materials Testing; Nerve Growth Factors; Nerve Regeneration; Peripheral Nerve Injuries; Peripheral Nerves; Piperidines; Polyesters; Polymers; Prosthesis Design; Temperature; Thiazoles | 2005 |
Cell viability of chitosan-containing semi-interpenetrated hydrogels based on PCL-PEG-PCL diacrylate macromer.
Topics: Acrylates; Animals; Biocompatible Materials; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Coloring Agents; Drug Delivery Systems; Fibroblasts; Hot Temperature; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Lactic Acid; Light; Mice; NIH 3T3 Cells; Nitrogen; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polymers; Polystyrenes; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays; Water | 2005 |
Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution.
Topics: Aldehyde Reductase; Animals; Benzothiazoles; Dialysis Solutions; Enzyme Inhibitors; Fibrosis; Glucose; Infusions, Parenteral; Lactic Acid; Male; Models, Animal; Neovascularization, Pathologic; Peritoneal Dialysis; Peritoneal Diseases; Peritoneum; Phthalazines; Polymers; Rats; Signal Transduction; Thiazoles | 2005 |
Distinct effects of short- and long-term leptin treatment on glucose and fatty acid uptake and metabolism in HL-1 cardiomyocytes.
Topics: Animals; Carrier Proteins; CD36 Antigens; Cell Line; Deoxyglucose; Fatty Acid Transport Proteins; Fatty Acids; Glucose; Glycogen; Hypoglycemic Agents; Immunoblotting; Insulin; Lactic Acid; Leptin; Mice; Myocytes, Cardiac; Oxidation-Reduction; Receptors, Leptin; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2006 |
Total synthesis and biological evaluation of (+)- and (-)-Butyl ester of rosmarinic acid.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Cinnamates; Depsides; Drug Screening Assays, Antitumor; Esters; Humans; In Vitro Techniques; Isodon; Lactic Acid; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Menthol; Microsomes, Liver; Molecular Conformation; Rats; Rosmarinic Acid; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment; Tetrazolium Salts; Thiazoles | 2006 |
Phase-sensitive polymer-based controlled delivery systems of leuprolide acetate: in vitro release, biocompatibility, and in vivo absorption in rabbits.
Topics: Animals; Antineoplastic Agents, Hormonal; Biocompatible Materials; Chemistry, Pharmaceutical; Data Interpretation, Statistical; Drug Compounding; Drug Delivery Systems; Intestinal Absorption; Lactic Acid; Leuprolide; Materials Testing; Polyesters; Polymers; Rabbits; Solubility; Testosterone; Tetrazolium Salts; Thiazoles | 2007 |
Poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, High Pressure Liquid; Coumarins; Drug Compounding; Fluorescent Dyes; Glioma; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pressure; Tetrazolium Salts; Thiazoles | 2007 |
Behaviors of keratinocytes and fibroblasts on films of PLA50-PEO-PLA50 triblock copolymers with various PLA segment lengths.
Topics: Cell Culture Techniques; Culture Media; Ethylene Oxide; Fibroblasts; Humans; Keratinocytes; Lactic Acid; Magnetic Resonance Spectroscopy; Polyesters; Polyethylene Glycols; Polymers; Polystyrenes; Skin; Spectrophotometry, Infrared; Tetrazolium Salts; Thiazoles; Tissue Engineering | 2008 |
PLGA, chitosan or chitosan-coated PLGA microparticles for alveolar delivery? A comparative study of particle stability during nebulization.
Topics: Adhesiveness; Administration, Inhalation; Antibiotics, Antitubercular; Cell Line; Chemical Phenomena; Chemistry, Physical; Chitosan; Diffusion; Drug Compounding; Drug Delivery Systems; Drug Stability; Electrochemistry; Emulsions; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Mucins; Mucous Membrane; Nebulizers and Vaporizers; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pulmonary Alveoli; Rifampin; Solvents; Tetrazolium Salts; Thiazoles | 2008 |
Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Thiazoles | 2009 |
PPARdelta agonism inhibits skeletal muscle PDC activity, mitochondrial ATP production and force generation during prolonged contraction.
Topics: Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Electric Stimulation; Glucose; Lactic Acid; Male; Mitochondria, Muscle; Muscle Contraction; Muscle, Skeletal; Oxidation-Reduction; PPAR delta; Pyruvate Dehydrogenase Complex; Rats; Rats, Wistar; Thiazoles | 2009 |
Ultrafine PEG-PLA fibers loaded with both paclitaxel and doxorubicin hydrochloride and their in vitro cytotoxicity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Chemistry, Pharmaceutical; Doxorubicin; Drug Delivery Systems; Flow Cytometry; Humans; In Vitro Techniques; Lactic Acid; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Rats; Technology, Pharmaceutical; Tetrazolium Salts; Thiazoles | 2009 |
The behavior of mesenchymal stem cells on micropatterned PLLA membranes.
Topics: Adult; Biocompatible Materials; Bone Marrow Cells; Cell Adhesion; Cell Survival; Dimethylpolysiloxanes; Elastomers; Flow Cytometry; Humans; Lactic Acid; Mesenchymal Stem Cells; Middle Aged; Polyesters; Polymers; Silicones; Surface Properties; Tetrazolium Salts; Thiazoles | 2009 |
Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Microscopy, Confocal; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Thiazoles; Xenograft Model Antitumor Assays | 2009 |
Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antioxidants; Bentonite; Cell Line; Coumarins; Docetaxel; Drug Carriers; Drug Delivery Systems; Drug Therapy; Humans; Lactic Acid; Male; Nanoparticles; Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Taxoids; Thiazoles; Vitamin E | 2009 |
Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2009 |
Effective antiproliferative effect of meloxicam on prostate cancer cells: development of a new controlled release system.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Lactic Acid; Male; Meloxicam; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostatic Neoplasms; Thiazines; Thiazoles; Time Factors | 2010 |
Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles.
Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Chitosan; Coumarins; Drug Carriers; Female; Flow Cytometry; Fluorescence; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Surface Properties; Technology, Pharmaceutical; Thiazoles; Tissue Distribution | 2010 |
Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Fluorouracil; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2010 |
Penetration and distribution of PLGA nanoparticles in the human skin treated with microneedles.
Topics: Administration, Cutaneous; Chromatography, High Pressure Liquid; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Female; Humans; In Vitro Techniques; Lactic Acid; Microscopy, Confocal; Nanoparticles; Needles; Particle Size; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Skin Absorption; Thiazoles | 2010 |
Expression of osteoclastogenesis inducers in a tissue model of periodontal ligament under compression.
Topics: Adolescent; Biocompatible Materials; Biomechanical Phenomena; Cell Culture Techniques; Cell Survival; Coloring Agents; Fibroblast Growth Factor 2; Fibroblasts; Gingiva; Humans; Interleukin-11; Interleukin-8; Lactic Acid; Microscopy, Fluorescence; Osteoclasts; Parathyroid Hormone-Related Protein; Periodontal Ligament; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RANK Ligand; Stress, Mechanical; Tetrazolium Salts; Thiazoles; Time Factors; Tissue Scaffolds; Tooth Movement Techniques; Up-Regulation | 2011 |
Effects of surface modification on delivery efficiency of biodegradable nanoparticles across the blood-brain barrier.
Topics: Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Cell Line; Cell Line, Tumor; Coumarins; Docetaxel; Dogs; Drug Carriers; Humans; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Taxoids; Thiazoles | 2011 |
Delivery of polymeric particles into skin using needle-free liquid jet injectors.
Topics: Coumarins; Drug Delivery Systems; Humans; In Vitro Techniques; Injections, Jet; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polystyrenes; Skin; Solubility; Surface Properties; Thiazoles | 2011 |
Changes in 2-fluoro-2-deoxy-D-glucose incorporation, hexokinase activity and lactate production by breast cancer cells responding to treatment with the anti-HER-2 antibody trastuzumab.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Fluorodeoxyglucose F18; Glucose; Hexokinase; Humans; Lactic Acid; Receptor, ErbB-2; Tetrazolium Salts; Thiazoles; Trastuzumab; Tumor Stem Cell Assay | 2011 |
High-throughput screening of PLGA thin films utilizing hydrophobic fluorescent dyes for hydrophobic drug compounds.
Topics: Cardiovascular Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coated Materials, Biocompatible; Coumarins; Delayed-Action Preparations; Drug Carriers; Fluoresceins; Fluorescent Dyes; High-Throughput Screening Assays; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy; Microscopy, Electron, Scanning; Molecular Structure; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Solubility; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Surface Properties; Technology, Pharmaceutical; Thiazoles | 2011 |
Novel scaffold design with multi-grooved PLA fibers.
Topics: Animals; Biocompatible Materials; Cell Survival; Fibroblasts; Lactic Acid; Materials Testing; Mice; Microscopy, Electron, Scanning; NIH 3T3 Cells; Photoelectron Spectroscopy; Polyesters; Polymers; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Tetrazolium Salts; Textiles; Thiazoles; Tissue Engineering | 2011 |
Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: the role of size for intraocular drug delivery.
Topics: Animals; Axons; Coumarins; Drug Delivery Systems; ErbB Receptors; Female; Lactic Acid; Microscopy, Fluorescence; Microspheres; Models, Chemical; Nanospheres; Nerve Regeneration; Neurons; Optic Nerve; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Sprague-Dawley; Thiazoles; Tyrphostins | 2011 |
Self-assembled polymersomes conjugated with lactoferrin as novel drug carrier for brain delivery.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Caspase 3; Coumarins; Cryoelectron Microscopy; Drug Carriers; Lactic Acid; Lactoferrin; Liposomes; Male; Mice; Mice, Inbred BALB C; Particle Size; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Surface Properties; Thiazoles; Tissue Distribution | 2012 |
Solanum tuberosum lectin-conjugated PLGA nanoparticles for nose-to-brain delivery: in vivo and in vitro evaluations.
Topics: Administration, Intranasal; Animals; Anura; Brain; Cell Line, Tumor; Cell Survival; Chitin; Cilia; Coumarins; Drug Delivery Systems; Endocytosis; Humans; Imidazoles; Lactic Acid; Male; Nanoparticles; Particle Size; Plant Lectins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Surface Properties; Thiazoles | 2012 |
Control of cell nucleus shapes via micropillar patterns.
Topics: Animals; Animals, Newborn; Bone Marrow Cells; Cell Differentiation; Cell Nucleus; Cell Nucleus Shape; Cell Proliferation; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Stromal Cells; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Enhanced transdermal delivery of indomethacin using combination of PLGA nanoparticles and iontophoresis in vivo.
Topics: Administration, Cutaneous; Animals; Coumarins; Drug Delivery Systems; Indomethacin; Iontophoresis; Lactic Acid; Microscopy, Confocal; Nanoparticles; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Thiazoles | 2012 |
Nanoformulation of siRNA silencing Bcl-2 gene and its implication in cancer therapy.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Coloring Agents; Drug Compounding; Drug Delivery Systems; Electrochemistry; Female; Fluorescent Antibody Technique; Gene Silencing; Genes, bcl-2; Genetic Therapy; Humans; Lactic Acid; Male; Mice; Nanoparticles; Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Reverse Transcriptase Polymerase Chain Reaction; Rhodamines; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2011 |
3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Survival; Citric Acid; D-Amino-Acid Oxidase; Electrophoresis, Polyacrylamide Gel; Glioblastoma; Glioma; Glycolysis; Humans; Hydrogen Peroxide; Immunoblotting; Lactic Acid; Oxidative Stress; Pyruvates; Pyruvic Acid; Tetrazolium Salts; Thiazoles | 2012 |
Preparation and in vitro evaluation of meloxicam-loaded PLGA nanoparticles on HT-29 human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Biological Transport; Cell Survival; Chemistry, Pharmaceutical; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Carriers; Drug Stability; HT29 Cells; Humans; Kinetics; Lactic Acid; Meloxicam; Molecular Weight; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Solubility; Surface Properties; Thiazines; Thiazoles | 2012 |
Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Breast Neoplasms; Butyrates; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Pyruvates; Tetrazolium Salts; Thiazoles | 2012 |
In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa.
Topics: Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Leishmania infantum; Macrophages; Mice; Nanoparticles; Polyesters; Polymers; Quinolones; Tetrazolium Salts; Thiazoles | 2012 |
SOX9 gene plus heparinized TGF-β 3 coated dexamethasone loaded PLGA microspheres for inducement of chondrogenesis of hMSCs.
Topics: Animals; Cell Adhesion; Cell Survival; Chondrocytes; Dexamethasone; Female; Gene Expression Regulation; Glycosaminoglycans; Heparin; Humans; Lactic Acid; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; SOX9 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Transforming Growth Factor beta3 | 2012 |
Chitosan/PLA nanoparticles as a novel carrier for the delivery of anthraquinone: synthesis, characterization and in vitro cytotoxicity evaluation.
Topics: Annexin A5; Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chitosan; DNA Fragmentation; DNA, Neoplasm; Drug Carriers; Drug Compounding; Drug Delivery Systems; Electrophoresis, Agar Gel; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Necrosis; Particle Size; Polyesters; Polymers; Tetrazolium Salts; Thiazoles | 2013 |
Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells.
Topics: Cell Line, Tumor; Coloring Agents; Energy Metabolism; Glioma; Glucose; Glycation End Products, Advanced; Glycine; Humans; Lactic Acid; Lactoylglutathione Lyase; Neutral Red; Oxidation-Reduction; Propidium; Pyruvaldehyde; Tetrazolium Salts; Thiazoles; Thiolester Hydrolases | 2012 |
Preparation and characterization of teniposide PLGA nanoparticles and their uptake in human glioblastoma U87MG cells.
Topics: Acetone; Antineoplastic Agents; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Coumarins; Drug Carriers; Endocytosis; Fluorescent Dyes; Glioblastoma; Humans; Lactic Acid; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Teniposide; Thiazoles | 2012 |
A physical model for the size-dependent cellular uptake of nanoparticles modified with cationic surfactants.
Topics: Caco-2 Cells; Cations; Coumarins; Emulsions; HT29 Cells; Humans; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quaternary Ammonium Compounds; Structure-Activity Relationship; Surface-Active Agents; Thiazoles | 2012 |
Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; Chymotrypsin; Citrate (si)-Synthase; Electron Transport Complex I; Female; Green Fluorescent Proteins; Humans; Immunoprecipitation; Lactic Acid; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Neuroblastoma; Parkinson Disease; Plasma; Proteasome Endopeptidase Complex; RNA, Small Interfering; Statistics as Topic; Tetrazolium Salts; Thiazoles; Transfection; Ubiquitin; Ubiquitination; Up-Regulation | 2012 |
Novel dental adhesive containing antibacterial agents and calcium phosphate nanoparticles.
Topics: Ammonium Compounds; Anti-Bacterial Agents; Biofilms; Calcium Phosphates; Cell Survival; Dental Caries; Dental Cements; Dentin; Humans; Lactic Acid; Metal Nanoparticles; Methacrylates; Microscopy, Electron, Transmission; Saliva; Silver; Stem Cells; Tetrazolium Salts; Thiazoles | 2013 |
Development of meloxicam in situ implant formulation by quality by design principle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Implants; Gels; Inhibitory Concentration 50; Lactic Acid; Male; Meloxicam; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Thiazines; Thiazoles; Viscosity; X-Ray Diffraction | 2014 |
Usefulness of controlled release of growth factors in investigating the early events of dentin-pulp regeneration.
Topics: Adolescent; Antigens, Surface; Cell Culture Techniques; Cell Migration Assays; Cell Movement; Cell Proliferation; Cell Survival; Chemotactic Factors; Coloring Agents; Delayed-Action Preparations; Dental Pulp; Dentin; Diffusion Chambers, Culture; Drug Carriers; Fibroblast Growth Factor 2; Flow Cytometry; Humans; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Regeneration; Stem Cells; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta1 | 2013 |
Distribution and deposition of respirable PLGA microspheres in lung alveoli.
Topics: Administration, Inhalation; Animals; Antibiotics, Antitubercular; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Coumarins; Fluorescence; Immunoenzyme Techniques; Lactic Acid; Lung; Macrophages, Alveolar; Male; Microspheres; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Rifampin; Thiazoles; Tissue Distribution; Trachea | 2013 |
Oligoarginine-modified biodegradable nanoparticles improve the intestinal absorption of insulin.
Topics: Animals; Biological Availability; Blood Glucose; Caco-2 Cells; Cell Survival; Cell-Penetrating Peptides; Coumarins; Humans; Ileum; Insulin; Intestinal Absorption; L-Lactate Dehydrogenase; Lactic Acid; Male; Nanoparticles; Oligopeptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Thiazoles | 2013 |
Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, Gel; Coumarins; Docetaxel; Female; Humans; Inhibitory Concentration 50; Lactic Acid; Magnetic Resonance Spectroscopy; Mannitol; MCF-7 Cells; Molecular Weight; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Taxoids; Thermogravimetry; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Combined effect of PLGA and curcumin on wound healing activity.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Cell Survival; Collagen; Curcumin; Female; Glutathione Peroxidase; Keratinocytes; L-Lactate Dehydrogenase; Lactic Acid; Mice; Nanoparticles; NF-kappa B; Peroxidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Tetrazolium Salts; Thiazoles; Wound Healing | 2013 |
Modulation of the foreign body response to implanted sensor models through device-based delivery of the tyrosine kinase inhibitor, masitinib.
Topics: Animals; Benzamides; Biocompatible Materials; Biosensing Techniques; Foreign-Body Reaction; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Piperidines; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostheses and Implants; Protein Kinase Inhibitors; Pyridines; Thiazoles | 2013 |
A rationally designed photo-chemo core-shell nanomedicine for inhibiting the migration of metastatic breast cancer cells followed by photodynamic killing.
Topics: Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Dasatinib; Drug Carriers; Female; Humans; Lactic Acid; Mesoporphyrins; Molecular Docking Simulation; Nanomedicine; Neoplasm Metastasis; Photochemotherapy; Photosensitizing Agents; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein-Tyrosine Kinases; Pyrimidines; Serum Albumin; Thiazoles | 2014 |
Multilayered polymer-coated carbon nanotubes to deliver dasatinib.
Topics: Cell Proliferation; Dasatinib; Drug Delivery Systems; Glioblastoma; Humans; Kinetics; Lactic Acid; Microscopy, Electron, Transmission; Nanoparticles; Nanotubes, Carbon; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymerization; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Thiazoles; Tumor Cells, Cultured | 2014 |
Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; Animals; Dose-Response Relationship, Drug; Drug Discovery; Flushing; High-Throughput Screening Assays; Hypolipidemic Agents; Injections, Intraperitoneal; Lactic Acid; Lipolysis; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Receptors, G-Protein-Coupled; Structure-Activity Relationship; Thiazoles; Transfection | 2014 |
iNGR-modified PEG-PLGA nanoparticles that recognize tumor vasculature and penetrate gliomas.
Topics: Administration, Intravenous; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Collagen; Coumarins; Drug Combinations; Endocytosis; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Kaplan-Meier Estimate; Lactic Acid; Laminin; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteoglycans; Rats; Rats, Sprague-Dawley; Spectroscopy, Near-Infrared; Thiazoles; Tissue Distribution; Treatment Outcome | 2014 |
Nanoparticles as drug delivery system against tuberculosis in zebrafish embryos: direct visualization and treatment.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Coumarins; Drug Carriers; Embryo, Nonmammalian; Granuloma; Lactic Acid; Macrophages; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Nanoparticles; Optical Imaging; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Rifampin; Thiazoles; Tuberculosis; Zebrafish | 2014 |
A polymer-protein core-shell nanomedicine for inhibiting cancer migration followed by photo-triggered killing.
Topics: Albumins; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Dasatinib; Drug Carriers; Humans; Lactic Acid; Male; Nanomedicine; Photosensitizing Agents; Phototherapy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porphyrins; Pyrimidines; Rats; Rats, Wistar; Thiazoles | 2014 |
A novel oleanolic acid-loaded PLGA-TPGS nanoparticle for liver cancer treatment.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Coumarins; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Oleanolic Acid; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Thiazoles; Vitamin E | 2015 |
Dual-modality, fluorescent, PLGA encapsulated bismuth nanoparticles for molecular and cellular fluorescence imaging and computed tomography.
Topics: Animals; Apoptosis; Bismuth; Cell Proliferation; Cell Survival; Chickens; Contrast Media; Coumarins; Lactic Acid; Lysosomes; Male; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Temperature; Thiazoles; Tomography, X-Ray Computed; X-Ray Microtomography | 2014 |
Multiassay analysis of the toxic potential of hydrogen peroxide on cultured neurons.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebellum; Extracellular Fluid; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lactic Acid; Neurons; Oxidants; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles | 2015 |
Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment.
Topics: Animals; Catalase; Cells, Cultured; Collagen; Delayed-Action Preparations; Diabetes Mellitus; Drug Delivery Systems; Fibroblasts; Glutathione Peroxidase; HEK293 Cells; Humans; Hydrogen Peroxide; Lactic Acid; Male; Mice; Microscopy, Electron, Scanning; Oxidation-Reduction; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; PPAR delta; PPAR-beta; Reactive Oxygen Species; Thiazoles; Wound Healing | 2015 |
Surface association and uptake of poly(lactic-co-glycolic) acid nanoparticles by Aspergillus flavus.
Topics: Aspergillus flavus; Chemistry, Pharmaceutical; Coumarins; Drug Carriers; Fluorescent Dyes; Hyphae; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Spores, Fungal; Surface Properties; Technology, Pharmaceutical; Thiazoles; Time Factors | 2014 |
Intranasal and intravenous administration of octa-arginine modified poly(lactic-co-glycolic acid) nanoparticles facilitates central nervous system delivery of loperamide.
Topics: Administration, Intranasal; Administration, Intravenous; Analgesics; Animals; Arginine; Cell Line; Central Nervous System; Coumarins; Dogs; Drug Delivery Systems; Female; Lactic Acid; Loperamide; Male; Mice, Inbred C57BL; Nanoconjugates; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Thiazoles | 2015 |
Synthesis and structural reconfirmation of bacillamide B.
Topics: Biological Products; Chemistry Techniques, Synthetic; Lactic Acid; Stereoisomerism; Thiazoles; Tryptamines | 2015 |
Adding vitamin E-TPGS to the formulation of Genexol-PM: specially mixed micelles improve drug-loading ability and cytotoxicity against multidrug-resistant tumors significantly.
Topics: Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Chemistry, Pharmaceutical; Coumarins; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Space; Lactic Acid; Micelles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Spheroids, Cellular; Thiazoles; Vitamin E | 2015 |
Exercise-induced changes in tumour LDH-B and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice.
Topics: Animals; Basigin; Breast Neoplasms; Cell Line, Tumor; ERRalpha Estrogen-Related Receptor; Female; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Mice, Inbred BALB C; Monocarboxylic Acid Transporters; Muscle Proteins; Nitriles; Physical Conditioning, Animal; Receptors, Estrogen; Symporters; Thiazoles; Tumor Burden | 2015 |
Effects of X-shaped reduction-sensitive amphiphilic block copolymer on drug delivery.
Topics: Apoptosis; Biocompatible Materials; Cell Line, Tumor; Coumarins; Docetaxel; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Micelles; Microscopy, Fluorescence; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Spectroscopy, Fourier Transform Infrared; Taxoids; Thiazoles | 2015 |
Intracellular localization and dynamics of Hypericin loaded PLLA nanocarriers by image correlation spectroscopy.
Topics: Anthracenes; Biological Transport; Cell Line, Tumor; Coumarins; Drug Carriers; Fluorescent Dyes; Humans; Lactic Acid; Nanoparticles; Perylene; Polyesters; Polymers; Spectrum Analysis; Thiazoles | 2015 |
Controlled association and delivery of nanoparticles from jet-sprayed hybrid microfibrillar matrices.
Topics: Adsorption; Coumarins; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Electrophoresis, Polyacrylamide Gel; Lactic Acid; Microfibrils; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Muramidase; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Thiazoles | 2016 |
Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bufanolides; Coumarins; Drug Carriers; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Male; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles; Vitamin E | 2016 |
Nitazoxanide induces in vitro metabolic acidosis in Taenia crassiceps cysticerci.
Topics: Albendazole; Animals; Anticestodal Agents; Antiparasitic Agents; Female; Glucose; Glycolysis; Lactic Acid; Mice; Mice, Inbred BALB C; Nitro Compounds; Pyruvic Acid; Taenia; Thiazoles | 2016 |
Co-delivery of docetaxel and curcumin prodrug via dual-targeted nanoparticles with synergistic antitumor activity against prostate cancer.
Topics: Aconitic Acid; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Coumarins; Curcumin; Docetaxel; Drug Delivery Systems; Drug Liberation; Drug Stability; Drug Synergism; Endocytosis; Humans; Inhibitory Concentration 50; Lactic Acid; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prodrugs; Prostatic Neoplasms; Proton Magnetic Resonance Spectroscopy; Taxoids; Thiazoles | 2017 |
Pharmacokinetics, Metabolism, and Partial Biodistribution of "Pincer Therapeutic" Nitazoxanide in Mice following Pulmonary Delivery of Inhalable Particles.
Topics: Administration, Inhalation; Animals; Chromatography, High Pressure Liquid; Dry Powder Inhalers; Half-Life; Lactic Acid; Lung; Macrophages, Alveolar; Male; Mice; Nitro Compounds; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tandem Mass Spectrometry; Thiazoles; Tissue Distribution | 2017 |
Enhanced antitumor activity in A431 cells via encapsulation of 20(R)-ginsenoside Rg3 in PLGA nanoparticles.
Topics: Antineoplastic Agents; Cell Proliferation; Ginsenosides; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles | 2017 |
Modulation of periodontitis progression using pH-responsive nanosphere encapsulating metronidazole or N-phenacylthialzolium bromide.
Topics: Animals; Anti-Infective Agents; Chitosan; Disease Models, Animal; Disease Progression; Lactic Acid; Metronidazole; Nanospheres; Periodontitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles | 2018 |
Dual tumor-targeted poly(lactic-
Topics: Animals; Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Carriers; Drug Delivery Systems; Embryo, Nonmammalian; Folic Acid; HeLa Cells; Humans; Lactic Acid; Materials Testing; Nanoparticles; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Tetrazolium Salts; Thiazoles; Zebrafish | 2017 |
In vivo treatment with nitazoxanide induces anaerobic metabolism in experimental intraperitoneal cysticercosis.
Topics: Anaerobiosis; Animals; Anticestodal Agents; Chromatography, High Pressure Liquid; Cysticercosis; Energy Metabolism; Female; Glucose; Host-Parasite Interactions; Ketoglutaric Acids; Lactic Acid; Mice; Mice, Inbred BALB C; Nitro Compounds; Taenia; Thiazoles | 2017 |
Understanding the translocation mechanism of PLGA nanoparticles across round window membrane into the inner ear: a guideline for inner ear drug delivery based on nanomedicine.
Topics: Animals; Coumarins; Drug Delivery Systems; Endocytosis; Exocytosis; Humans; Lactic Acid; Lysosomes; Microscopy, Confocal; Models, Biological; Nanomedicine; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Round Window, Ear; Thiazoles | 2018 |
GPR119 agonist enhances gefitinib responsiveness through lactate-mediated inhibition of autophagy.
Topics: Animals; Autophagy; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; Female; Gefitinib; Humans; Lactic Acid; MCF-7 Cells; Mesylates; Mice, Inbred BALB C; Mice, Nude; Oxadiazoles; Receptors, G-Protein-Coupled; Tetrazoles; Thiazoles; Transfection | 2018 |
Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci.
Topics: Administration, Oral; Animals; Anthelmintics; Chromatography, High Pressure Liquid; Cysticercus; Energy Metabolism; Fatty Acids; Gluconeogenesis; Glucose; Lactic Acid; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Neurocysticercosis; Nitro Compounds; Oxaloacetic Acid; Oxidation-Reduction; Pyruvic Acid; Taenia; Thiazoles | 2019 |
Development of fibrous PLGA/fibrin scaffolds as a potential skin substitute.
Topics: Animals; Cell Adhesion; Cell Survival; Cells, Cultured; Fibrin; Formates; Lactic Acid; Male; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar; Skin, Artificial; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tensile Strength; Tetrazolium Salts; Thiazoles; Tissue Engineering; Tissue Scaffolds | 2020 |
Ratiometric Fluorescent Biosensors for Glucose and Lactate Using an Oxygen-Sensing Membrane.
Topics: Biosensing Techniques; Catalysis; Coumarins; Fluorescence; Fluorescent Dyes; Glucose; Glucose Oxidase; Humans; Lactic Acid; Limit of Detection; Oxygen; Platinum; Porphyrins; Spectrometry, Fluorescence; Thiazoles | 2021 |
Surface-modified polylactic acid nanospheres with chitosan for antibacterial activity of 1, 2-benzisothiazolin-3-one.
Topics: Anti-Bacterial Agents; Chitosan; Escherichia coli; Humans; Lactic Acid; Microscopy, Electron, Scanning; Nanospheres; Oxidative Stress; Particle Size; Polyesters; Reactive Oxygen Species; Staphylococcus aureus; Thiazoles | 2021 |