Compounds > lactic acid

lactic acid and syrosingopine

lactic acid has been researched along with syrosingopine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Benjamin, D; Colombi, M; El-Shemerly, MY; Hall, MN; Hindupur, SK; Lane, HA; Maira, SM; Moroni, C; Pohlmann, J; Robay, D1
Eliopoulos, E; Papakonstantinou, E; Thireou, T; Vlachakis, D; Vlachoyiannopoulos, PG1
Ates, G; De Bruyne, E; De Veirman, K; Faict, S; Fan, R; Maes, A; Massie, A; Menu, E; Oudaert, I; Satilmis, H; Van der Vreken, A; Vanderkerken, K; Vlummens, P1
Guo, F; He, C; Qin, J; Wang, P; Wang, Y; Wu, S; Xu, L1

Other Studies

4 other study(ies) available for lactic acid and syrosingopine

ArticleYear
Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells.
    Cell reports, 2018, 12-11, Volume: 25, Issue:11

    Topics: Acids; Animals; Cell Line, Tumor; Energy Metabolism; Humans; Intracellular Space; Lactic Acid; Male; Metformin; Mice, Inbred C57BL; Monocarboxylic Acid Transporters; Muscle Proteins; NAD; Neoplasms; Reserpine; Symporters; Synthetic Lethal Mutations

2018
A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4).
    International journal of molecular sciences, 2021, Mar-13, Volume: 22, Issue:6

    Topics: Animals; Antineoplastic Agents; Binding Sites; Biological Transport; Drug Design; Glycolysis; Humans; Lactic Acid; Molecular Docking Simulation; Monocarboxylic Acid Transporters; Muscle Proteins; Phloretin; Phylogeny; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Isoforms; Pyrimidinones; Quercetin; Reserpine; Structural Homology, Protein; Substrate Specificity; Thiophenes; Uracil

2021
Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis.
    The Journal of pathology, 2023, Volume: 260, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Lactic Acid; Metformin; Monocarboxylic Acid Transporters; Multiple Myeloma

2023
Lactate Efflux Inhibition by Syrosingopine/LOD Co-Loaded Nanozyme for Synergetic Self-Replenishing Catalytic Cancer Therapy and Immune Microenvironment Remodeling.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:26

    Topics: Biological Transport; Humans; Lactic Acid; Neoplasms; Tumor Microenvironment

2023