lactic acid has been researched along with rifampin in 78 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (6.41) | 18.2507 |
2000's | 28 (35.90) | 29.6817 |
2010's | 41 (52.56) | 24.3611 |
2020's | 4 (5.13) | 2.80 |
Authors | Studies |
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Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Denkbaş, EB; Kaitian, X; Pişkin, E; Tuncel, A | 1 |
Curran, TM; Ma, Y; Marquis, RE | 1 |
Blom, H; Borch, E; Dainty, R; Hagtvedt, T; Nerbrink, E; Nesbakken, T; Nissen, H | 1 |
Bain, DF; Cox, PJ; Munday, DL | 1 |
Hickey, AJ; O'Hara, P | 1 |
Dutt, M; Khuller, GK | 4 |
Hickey, AJ; Hopfer, R; Kazantseva, M; McMurray, DN; Newcomer, CE; O'Hara, P; Suarez, S | 1 |
Donald, PR; Elshof, JW; Janse van Rensburg, A; Laubscher, JA; Schoeman, JF | 1 |
Hu, J; Jiang, X; Zhang, W; Zhu, C | 1 |
Ain, Q; Garg, SK; Khuller, GK; Sharma, S | 1 |
Hickey, AJ; Sethuraman, VV | 1 |
Khuller, GK; Sharma, S; Ul-Ain, Q | 1 |
Bian, X; Chen, X; Jing, X; Liang, Q; Xu, X; Yang, L; Zeng, J | 1 |
Khuller, GK; Pandey, R; Prasad, B; Sharma, A; Sharma, S; Zahoor, A | 1 |
Khuller, GK; Pandey, R; Sharma, S; Zahoor, A | 1 |
Khuller, GK; Pandey, R | 1 |
Ando, S; Inagawa, H; Ito, F; Kochi, C; Makino, K; Nakajima, T; Shikamura, M; Soma, G; Terada, H | 1 |
Kajimoto, M; Kojima, S; Makino, K; Nakajima, T; Tomoda, K; Watanabe, D | 1 |
Makino, K; Tomoda, K | 1 |
Hasegawa, T; Hinata, H; Hirota, K; Inagawa, H; Ito, F; Kochi, C; Makino, K; Soma, G; Terada, H | 1 |
Atyabi, F; Dinarvand, R; Esmaeili, F; Hosseini-Nasr, M; Rad-Malekshahi, M; Samadi, N | 1 |
Kawai, Y; Makino, K; Nakajima, T; Nishiwaki, M; Ohkoshi, T; Tomoda, K | 1 |
Antimisiaris, SG; Dracopoulos, V; Fadda, AM; Manca, ML; Mourtas, S | 1 |
Hirota, K; Inagawa, H; Kohchi, C; Makino, K; Soma, G; Terada, H; Tomoda, K | 1 |
Makino, K; Nakajima, T; Ohkoshi, T; Tomoda, K | 1 |
Fujimori, H; Honnami, H; Ito, F; Kanamura, K; Kawakami, H; Makino, K | 1 |
Antimisiaris, SG; Fadda, AM; Loy, G; Manca, ML; Zaru, M | 1 |
Kabasawa, T; Ohashi, K; Okada, H; Ozeki, T | 1 |
Durbin, D; Edwards, DA; Elbert, KJ; Garcia-Contreras, L; Hickey, AJ; Padilla, DJ; Peloquin, CA; Sung, JC; Verberkmoes, JL | 1 |
Doan, TV; Olivier, JC | 1 |
Hasegawa, T; Hirota, K; Inagawa, H; Kohchi, C; Makino, K; Nakajima, T; Soma, G; Terada, H | 1 |
Fujiwara, N; Haga, M; Makino, K; Miyazaki, M; Nakajima, T; Onoshita, T; Shimizu, Y; Terada, H; Yamaya, N; Yokoyama, M | 1 |
Balasubramanian, S; Malathi, S | 1 |
Couet, W; Doan, TV; Olivier, JC | 1 |
Guru, BR; Hali, M; McPharlin, CM; Panyam, J; Toti, US; Whittum-Hudson, JA; Wykes, SM | 1 |
Choonara, YE; du Toit, LC; Jarvis, DL; Khan, RA; Kumar, P; Murphy, CS; Ndesendo, VM; Pillay, V | 1 |
Hasegawa, T; Hirota, K; Makino, K; Nakajima, T; Terada, H | 1 |
Chen, X; Gu, Y; Lee, JH; Lee, WY; Monteiro, DA; Wang, H | 1 |
Feng, H; Hu, C; Zhu, C | 1 |
Burt, HM; Gilchrist, SE; Letchford, K; Needham, D; Rickard, DL | 1 |
Bardy, A; Brillault, J; Diab, R; Gontijo, AV; Olivier, JC | 1 |
McConville, JT; Son, YJ | 1 |
Booysen, LL; Brooks, E; du Plessis, LH; Gilliland, J; Gruppo, V; Hansen, R; Kalombo, L; Kotze, AF; Lenaerts, A; Lungenhofer, P; Semete-Makokotlela, B; Swai, HS | 1 |
Hirota, K; Kawamoto, T; Makino, K; Nakajima, T; Terada, H | 1 |
Cheung, KM; Kong, T; Shum, HC; To, MK; Wang, L; Wu, J; Yeung, KW | 1 |
Bach, H; Burt, HM; Fazli, L; Gilchrist, SE; Lange, D; Letchford, K | 1 |
Egge-Jacobsen, W; Fenaroli, F; Griffiths, G; Kalluru, R; Khuller, GK; Koster, G; Maleki, A; Nyström, B; Paulsen Madsen, M; Roberg-Larsen, H; Roos, N; Singh, A; Ulanova, L; Westmoreland, D; Wilson, S | 1 |
Balasubramanian, S; Divakar, S; Gajendiran, M; Raaman, N | 1 |
Chawla, R; Jaiswal, S; Mishra, B | 1 |
Raj, V; Rajan, M | 1 |
Benjaminsen, J; Fenaroli, F; Griffiths, G; Hildahl, J; Kolstad, T; Meijer, AH; Nyström, B; Roos, N; Skjeldal, FM; Ulanova, L; van der Vaart, M; Westmoreland, D | 1 |
Cao, X; Wei, K; Wei, X; Xu, W; Zhong, S | 1 |
Dube, A; Fonteh, P; Hayeshi, R; Khumalo, V; Labuschagne, P; Lubuschagne, P; Madziva, MT; Meyer, D; Naicker, B; Ndamase, A; Swai, H; Tukulula, M | 1 |
Hu, Y; Jiang, D; Li, J; Qiao, B; Wang, J; Wu, J; Zuo, Y | 1 |
Cao, ZD; Jiang, DM; Li, YJ; Wang, X; Wang, ZL; Wu, J; Yan, L; Yi, YF | 1 |
Anes, E; Bogoeva, V; Fenaroli, F; Griffiths, G; Hildahl, J; Kalluru, R; Pires, D; Speth, M; Vibe, CB; Wilson, SR | 1 |
To, MK; Wu, J; Yeung, KW; Zhao, X | 1 |
Leng, FF; Li, HY; Liang, S; Lu, JF; Sun, HL; Zhu, Y | 1 |
Almouazen, E; Bourgeois, S; Fessi, H; Kodjikian, L; Lee, MY; Pelletier, J; Renaud, F | 1 |
Britton, WJ; Chan, HK; Leung, SS; Parumasivam, T; Quan, DH; Triccas, JA | 1 |
Jiang, JM; Lin, Z; Ma, XM; Qu, DB; Sang, CH; Zhang, JW | 1 |
Dai, W; Duan, C; Feng, X; Johnson, H; Li, J; Li, X; Liu, Z; Xiu, B; Yang, X; Zhang, H; Zhang, X | 1 |
Attalla, SM; Carter, WG; Christie, D; Elmorsy, E; Fikry, E; Kocon, A; Nwidu, LL; Turner, R; Warren, A | 1 |
Ding, Z; Lei, Q; Li, M; Liang, Y; Lu, T; Wu, J | 1 |
Jiang, D; Liu, Y | 1 |
Chen, Z; Huang, J; Li, L; Li, Y; Zhang, G | 1 |
Fenaroli, F; Griffiths, G; Misaghian, D; Nunes, C; Pinheiro, M; Reis, S; Ulanova, LS; Vibe, C; Wilson, S; Winther-Larsen, HC; Zhu, K | 1 |
Hierlemann, T; Krajewski, S; Müller, I; Reinbold, J; Schlensak, C; Uhde, AK; Urich, L; Vogel, U; Weindl, T; Wendel, HP | 1 |
Wu, G; Wu, WG; Zheng, QX; Zhou, JB | 1 |
Bairy, I; Gaonkar, SL; Guru, BR; Hakkimane, SS; Shenoy, VP | 1 |
Da Costa, D; Exbrayat-Héritier, C; Megy, S; Primard, C; Rambaud, B; Terreux, R; Verrier, B | 1 |
Allison, A; Fouladkhah, AC | 1 |
Castañeda-Fernandez, C; Chávez-Santos, RM; Espitia-Pinzón, C; Kozina, A; Martínez, R; Silva-Miranda, M | 1 |
Bhandari, RK; Kaur, G; Khuller, GK; Malhotra, S; Mittal, BR; Pandey, AK; Pandey, S; Rather, I; Shafiq, N; Sharma, N; Shukla, J | 1 |
1 trial(s) available for lactic acid and rifampin
Article | Year |
---|---|
The effect of adjuvant steroid treatment on serial cerebrospinal fluid changes in tuberculous meningitis.
Topics: Adenylate Kinase; Antitubercular Agents; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Female; Globulins; Glucocorticoids; Glucose; Humans; Infant; Lactic Acid; Lymphocyte Count; Male; Neutrophils; Prednisone; Rifampin; Statistics, Nonparametric; Tuberculosis, Meningeal | 2001 |
77 other study(ies) available for lactic acid and rifampin
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Rifampicin-carrying poly(D,L-lactide) microspheres: loading and release.
Topics: Biocompatible Materials; Biodegradation, Environmental; Delayed-Action Preparations; Drug Carriers; Excipients; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Microspheres; Polyesters; Polymers; Rifampin; Solvents; Stereoisomerism; Temperature | 1995 |
Rapid procedure for acid adaptation of oral lactic-acid bacteria and further characterization of the response.
Topics: Acetic Acid; Anti-Bacterial Agents; Antibiotics, Antitubercular; Biological Transport; Biomass; Chloramphenicol; Culture Media; Fluorides; Glucose; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Lacticaseibacillus casei; Protein Biosynthesis; Proteins; Proton-Motive Force; Rifampin; Streptococcus; Streptococcus mutans; Transcription, Genetic | 1997 |
Addition of 2.5% lactate and 0.25% acetate controls growth of Listeria monocytogenes in vacuum-packed, sensory-acceptable servelat sausage and cooked ham stored at 4 degrees C.
Topics: Acetic Acid; Animals; Antibiotics, Antitubercular; Cattle; Cold Temperature; Colony Count, Microbial; Consumer Behavior; Data Collection; Food Packaging; Food Preservatives; Hydrogen-Ion Concentration; Lactic Acid; Listeria monocytogenes; Meat Products; Mutation; Parabens; Rifampin; Swine | 1997 |
Evaluation of biodegradable rifampicin-bearing microsphere formulations using a stability-indicating high-performance liquid chromatographic assay.
Topics: Antibiotics, Antitubercular; Antioxidants; Ascorbic Acid; Biocompatible Materials; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Reproducibility of Results; Rifampin | 1998 |
Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: manufacture and characterization.
Topics: Antibiotics, Antitubercular; Buffers; Desiccation; Drug Carriers; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Solvents; Surface Properties | 2000 |
Therapeutic efficacy of Poly(DL-lactide-Co-Glycolide)-encapsulated antitubercular drugs against Mycobacterium tuberculosis infection induced in mice.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Biocompatible Materials; Drug Combinations; Drug Compounding; Isoniazid; Lactic Acid; Mice; Mycobacterium tuberculosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Tissue Distribution; Tuberculosis | 2001 |
Chemotherapy of Mycobacterium tuberculosis infections in mice with a combination of isoniazid and rifampicin entrapped in Poly (DL-lactide-co-glycolide) microparticles.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Capsules; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Therapy, Combination; Female; Isoniazid; Lactic Acid; Male; Mice; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Treatment Outcome; Tuberculosis | 2001 |
Liposomes and PLG microparticles as sustained release antitubercular drug carriers--an in vitro-in vivo study.
Topics: Alkaline Phosphatase; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Aspartate Aminotransferases; Bilirubin; Delayed-Action Preparations; Drug Carriers; Female; Isoniazid; Lactic Acid; Liposomes; Liver; Male; Mice; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Tissue Distribution | 2001 |
Respirable PLGA microspheres containing rifampicin for the treatment of tuberculosis: screening in an infectious disease model.
Topics: Administration, Inhalation; Aerosols; Animals; Antibiotics, Antitubercular; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Evaluation, Preclinical; Guinea Pigs; Indicators and Reagents; Lactic Acid; Lung; Macrophages; Male; Microbial Sensitivity Tests; Microspheres; Mycobacterium tuberculosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Tuberculosis | 2001 |
[Study on the rifampicin polylactic acid microspheres for lung targeting].
Topics: Animals; Antibiotics, Antitubercular; Delayed-Action Preparations; Lactic Acid; Lung; Male; Microspheres; Polyesters; Polymers; Rabbits; Rifampin; Tissue Distribution | 1998 |
Role of poly [DL-lactide-co-glycolide] in development of a sustained oral delivery system for antitubercular drug(s).
Topics: Administration, Oral; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biocompatible Materials; Capsules; Delayed-Action Preparations; Drug Compounding; Female; Half-Life; Isoniazid; Lactic Acid; Male; Mice; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Solubility | 2002 |
Poly (DL-lactide-co-glycolide) microparticles as carriers for antimycobacterial drug rifampicin.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antibiotics, Antitubercular; Bilirubin; Biocompatible Materials; Drug Carriers; Drug Delivery Systems; Female; In Vitro Techniques; Lactic Acid; Liver; Male; Mice; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin | 2000 |
Powder properties and their influence on dry powder inhaler delivery of an antitubercular drug.
Topics: Administration, Inhalation; Aerosols; Antitubercular Agents; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Delivery Systems; Lactic Acid; Lactose; Microscopy, Electron, Scanning; Models, Chemical; Particle Size; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Powders; Rifampin; Surface Properties; Thermogravimetry; Time Factors | 2002 |
Chemotherapeutic potential of orally administered poly(lactide-co-glycolide) microparticles containing isoniazid, rifampin, and pyrazinamide against experimental tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biocompatible Materials; Biological Availability; Capsules; Drug Combinations; Drug Compounding; Isoniazid; Lactic Acid; Mice; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Tissue Distribution; Tuberculosis, Pulmonary | 2003 |
Biodegradable electrospun fibers for drug delivery.
Topics: Biodegradation, Environmental; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Delivery Systems; Endopeptidase K; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Microscopy, Electron, Scanning; Nanotechnology; Paclitaxel; Polyesters; Polymers; Rifampin; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Static Electricity; Surface-Active Agents | 2003 |
Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis.
Topics: Administration, Inhalation; Aerosols; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biological Availability; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry, Physical; Colony Count, Microbial; Drug Carriers; Drug Combinations; Drug Compounding; Female; Guinea Pigs; Half-Life; Injections, Intravenous; Isoniazid; Lactic Acid; Lung; Male; Microspheres; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Tuberculosis | 2003 |
Nanoparticle encapsulated antitubercular drugs as a potential oral drug delivery system against murine tuberculosis.
Topics: Administration, Oral; Animals; Antitubercular Agents; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Glycolates; Isoniazid; Lactic Acid; Liver; Lung; Male; Mice; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazinamide; Rifampin; Spleen; Tuberculosis | 2003 |
Subcutaneous nanoparticle-based antitubercular chemotherapy in an experimental model.
Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Biological Availability; Drug Combinations; Drug Compounding; Injections, Subcutaneous; Isoniazid; Lactic Acid; Lung; Mice; Microspheres; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Spleen; Tissue Distribution; Tuberculosis | 2004 |
Efficient intracellular delivery of rifampicin to alveolar macrophages using rifampicin-loaded PLGA microspheres: effects of molecular weight and composition of PLGA on release of rifampicin.
Topics: Animals; Antibiotics, Antitubercular; Cell Line; Culture Media; Delayed-Action Preparations; Drug Delivery Systems; Kinetics; Lactic Acid; Macrophages, Alveolar; Microspheres; Molecular Weight; Particle Size; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rifampin | 2004 |
Effects of pulmonary surfactant system on rifampicin release from rifampicin-loaded PLGA microspheres.
Topics: Lactic Acid; Macrophages, Alveolar; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pulmonary Surfactants; Rifampin | 2005 |
Effects of lung surfactants on rifampicin release rate from monodisperse rifampicin-loaded PLGA microspheres.
Topics: Humans; Lactic Acid; Microspheres; Molecular Weight; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pulmonary Surfactants; Rifampin; Surface Properties; Time Factors | 2007 |
Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages.
Topics: Animals; Cell Survival; Drug Carriers; Lactic Acid; Macrophages, Alveolar; Microspheres; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rifampin | 2007 |
Preparation and antibacterial activity evaluation of rifampicin-loaded poly lactide-co-glycolide nanoparticles.
Topics: Anti-Bacterial Agents; Bacteria; Cell Survival; Coated Materials, Biocompatible; Drug Carriers; Lactic Acid; Materials Testing; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin | 2007 |
Preparation and properties of inhalable nanocomposite particles: effects of the temperature at a spray-dryer inlet upon the properties of particles.
Topics: Administration, Inhalation; Calorimetry, Differential Scanning; Carbohydrates; Lactic Acid; Nanocomposites; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Temperature; Water | 2008 |
PLGA, chitosan or chitosan-coated PLGA microparticles for alveolar delivery? A comparative study of particle stability during nebulization.
Topics: Adhesiveness; Administration, Inhalation; Antibiotics, Antitubercular; Cell Line; Chemical Phenomena; Chemistry, Physical; Chitosan; Diffusion; Drug Compounding; Drug Delivery Systems; Drug Stability; Electrochemistry; Emulsions; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Mucins; Mucous Membrane; Nebulizers and Vaporizers; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pulmonary Alveoli; Rifampin; Solvents; Tetrazolium Salts; Thiazoles | 2008 |
Stimulation of phagocytic activity of alveolar macrophages toward artificial microspheres by infection with mycobacteria.
Topics: Animals; Cell Survival; Cells, Cultured; Escherichia coli; Lactic Acid; Macrophages, Alveolar; Microspheres; Mycobacterium; Mycobacterium bovis; Nitric Oxide; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rifampin; Tumor Necrosis Factor-alpha | 2008 |
Preparation and properties of inhalable nanocomposite particles: effects of the size, weight ratio of the primary nanoparticles in nanocomposite particles and temperature at a spray-dryer inlet upon properties of nanocomposite particles.
Topics: Administration, Inhalation; Aerosols; Antibiotics, Antitubercular; Lactic Acid; Nanocomposites; Nanoparticles; Nebulizers and Vaporizers; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Temperature | 2008 |
Effect of polyethylene glycol on preparation of rifampicin-loaded PLGA microspheres with membrane emulsification technique.
Topics: Antibiotics, Antitubercular; Drug Carriers; Drug Delivery Systems; Emulsions; Lactic Acid; Membranes, Artificial; Microspheres; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Rifampin | 2008 |
Release of rifampicin from chitosan, PLGA and chitosan-coated PLGA microparticles.
Topics: Chitosan; Drug Carriers; Drug Delivery Systems; Drug Stability; Kinetics; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin | 2008 |
One-step preparation of rifampicin/poly(lactic-co-glycolic acid) nanoparticle-containing mannitol microspheres using a four-fluid nozzle spray drier for inhalation therapy of tuberculosis.
Topics: Administration, Inhalation; Administration, Intranasal; Aerosols; Animals; Antibiotics, Antitubercular; Cell Line; Drug Carriers; Drug Compounding; Lactic Acid; Lung; Macrophages, Alveolar; Male; Mannitol; Microscopy, Electron, Scanning; Microspheres; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Rifampin; Surface Properties | 2009 |
Formulation and pharmacokinetics of self-assembled rifampicin nanoparticle systems for pulmonary delivery.
Topics: Animals; Antitubercular Agents; Chemistry, Pharmaceutical; Guinea Pigs; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin | 2009 |
Preparation of rifampicin-loaded PLGA microspheres for lung delivery as aerosol by premix membrane homogenization.
Topics: Acetates; Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Emulsions; Kinetics; Lactic Acid; Membranes, Artificial; Microspheres; Oils; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pressure; Rats; Rifampin; Solubility; Solvents; Technology, Pharmaceutical; Water | 2009 |
Delivery of rifampicin-PLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis.
Topics: Animals; Antibiotics, Antitubercular; Cell Line; Cell Survival; Drug Carriers; Interleukin-10; Lactic Acid; Macrophages, Alveolar; Microspheres; Mycobacterium bovis; Nitric Oxide; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rifampin; Tissue Distribution; Tuberculosis; Tumor Necrosis Factor-alpha | 2010 |
The behavior of PLGA microspheres containing rifampicin in alveolar macrophages.
Topics: Animals; Cell Line; Hydrogen-Ion Concentration; Lactic Acid; Macrophages, Alveolar; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rifampin; Time Factors | 2010 |
Synthesis of biodegradable polymeric nanoparticles and their controlled drug delivery for tuberculosis.
Topics: Absorbable Implants; Antitubercular Agents; Delayed-Action Preparations; Diffusion; Drug Compounding; Humans; Lactic Acid; Nanocapsules; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Tuberculosis | 2011 |
Formulation and in vitro characterization of inhalable rifampicin-loaded PLGA microspheres for sustained lung delivery.
Topics: Acetates; Aerosols; Antibiotics, Antitubercular; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Excipients; Lactic Acid; Lung; Membranes, Artificial; Microspheres; Models, Theoretical; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Solvents | 2011 |
Targeted delivery of antibiotics to intracellular chlamydial infections using PLGA nanoparticles.
Topics: Anti-Bacterial Agents; Azithromycin; Cell Line; Chemistry, Pharmaceutical; Chlamydia Infections; Chlamydia trachomatis; Coumarins; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Synergism; Humans; Intracellular Space; Lactic Acid; Microbial Sensitivity Tests; Microbial Viability; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Time Factors | 2011 |
Polymeric emulsion and crosslink-mediated synthesis of super-stable nanoparticles as sustained-release anti-tuberculosis drug carriers.
Topics: Alginates; Calcium Chloride; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Emulsions; Glucuronic Acid; Hexoses; Hexuronic Acids; Humans; Hydrogels; Isoniazid; Lactic Acid; Microscopy, Electron, Scanning; Models, Molecular; Nanoparticles; Organic Chemistry Phenomena; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Spectrum Analysis; Thermodynamics; Tuberculosis | 2011 |
Phagostimulatory effect of uptake of PLGA microspheres loaded with rifampicin on alveolar macrophages.
Topics: Animals; Antitubercular Agents; Cell Line; Drug Delivery Systems; Fluorescent Dyes; Lactic Acid; Macrophages, Alveolar; Microspheres; Particle Size; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polystyrenes; Rats; Rifampin; Tuberculosis | 2011 |
Inkjet printed antibiotic- and calcium-eluting bioresorbable nanocomposite micropatterns for orthopedic implants.
Topics: Alloys; Antibiotics, Antitubercular; Biofilms; Calcium; Calcium Phosphates; Cell Differentiation; Cell Proliferation; Cells, Cultured; Humans; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Nanocomposites; Orthopedic Fixation Devices; Osteoblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Printing; Rifampin; Staphylococcus epidermidis; Surface Properties; Titanium | 2012 |
Preparation and characterization of rifampicin-PLGA microspheres/sodium alginate in situ gel combination delivery system.
Topics: Alginates; Animals; Calorimetry, Differential Scanning; Drug Delivery Systems; Gels; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Male; Mice; Mice, Nude; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Rifampin; Surface Properties | 2012 |
Phase separation behavior of fusidic acid and rifampicin in PLGA microspheres.
Topics: Calorimetry, Differential Scanning; Drug Compounding; Fusidic Acid; Lactic Acid; Microscopy, Confocal; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Spectrum Analysis, Raman | 2012 |
Formulation and in vitro characterization of inhalable polyvinyl alcohol-free rifampicin-loaded PLGA microspheres prepared with sucrose palmitate as stabilizer: efficiency for ex vivo alveolar macrophage targeting.
Topics: Animals; Antibiotics, Antitubercular; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Lactic Acid; Macrophages, Alveolar; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Rats; Rats, Sprague-Dawley; Rifampin; Sucrose | 2012 |
Preparation of sustained release rifampicin microparticles for inhalation.
Topics: Administration, Inhalation; Aerosols; Antibiotics, Antitubercular; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Drug Stability; Drug Storage; Humans; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Molecular Conformation; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Rifampin; Solubility; Surface Properties; Water | 2012 |
In vivo/in vitro pharmacokinetic and pharmacodynamic study of spray-dried poly-(dl-lactic-co-glycolic) acid nanoparticles encapsulating rifampicin and isoniazid.
Topics: Animals; Antibiotics, Antitubercular; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Isoniazid; Lactic Acid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin | 2013 |
Distribution and deposition of respirable PLGA microspheres in lung alveoli.
Topics: Administration, Inhalation; Animals; Antibiotics, Antitubercular; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Coumarins; Fluorescence; Immunoenzyme Techniques; Lactic Acid; Lung; Macrophages, Alveolar; Male; Microspheres; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Rifampin; Thiazoles; Tissue Distribution; Trachea | 2013 |
Fabrication and characterization of monodisperse PLGA-alginate core-shell microspheres with monodisperse size and homogeneous shells for controlled drug release.
Topics: Alginates; Animals; Capsules; Cell Line; Cell Survival; Crystallization; Delayed-Action Preparations; Diffusion; Gels; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Materials Testing; Mice; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Surface Properties | 2013 |
Fusidic acid and rifampicin co-loaded PLGA nanofibers for the prevention of orthopedic implant associated infections.
Topics: Animals; Anti-Bacterial Agents; Arthroplasty, Replacement; Bacterial Infections; Drug Delivery Systems; Female; Fusidic Acid; Lactic Acid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nanofibers; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostheses and Implants; Prosthesis-Related Infections; Rats; Rats, Sprague-Dawley; Rifampin; Staphylococcus epidermidis | 2013 |
Poly(lactide-co-glycolide)-rifampicin nanoparticles efficiently clear Mycobacterium bovis BCG infection in macrophages and remain membrane-bound in phago-lysosomes.
Topics: Animals; Antibiotics, Antitubercular; Cell Line; Cell Membrane; Colony Count, Microbial; Drug Carriers; Female; Lactic Acid; Macrophages; Male; Mice; Mycobacterium bovis; Nanoparticles; Phagosomes; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin | 2013 |
In vitro drug release behavior, mechanism and antimicrobial activity of rifampicin loaded low molecular weight PLGA-PEG-PLGA triblock copolymeric nanospheres.
Topics: Anti-Bacterial Agents; Chromatography, Gel; Delayed-Action Preparations; Diffusion; Drug Carriers; Lactic Acid; Magnetic Resonance Spectroscopy; Microspheres; Molecular Weight; Nanospheres; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Spectroscopy, Fourier Transform Infrared; Tetracycline; Viscosity; X-Ray Diffraction | 2013 |
Development and optimization of polymeric nanoparticles of antitubercular drugs using central composite factorial design.
Topics: Animals; Antitubercular Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Isoniazid; Lactic Acid; Macrophages, Peritoneal; Male; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Rifampin | 2014 |
Formation and characterization of chitosan-polylacticacid-polyethylene glycol-gelatin nanoparticles: a novel biosystem for controlled drug delivery.
Topics: Chitosan; Delayed-Action Preparations; Drug Carriers; Gelatin; Lactic Acid; Mycobacterium smegmatis; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Rifampin; Solvents; Volatilization | 2013 |
Nanoparticles as drug delivery system against tuberculosis in zebrafish embryos: direct visualization and treatment.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Coumarins; Drug Carriers; Embryo, Nonmammalian; Granuloma; Lactic Acid; Macrophages; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Nanoparticles; Optical Imaging; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Rifampin; Thiazoles; Tuberculosis; Zebrafish | 2014 |
A mesoporous silicon/poly-(DL-lactic-co-glycolic) acid microsphere for long time anti-tuberculosis drug delivery.
Topics: Antitubercular Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Isoniazid; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Silicon Dioxide; Time Factors | 2014 |
Curdlan-Conjugated PLGA Nanoparticles Possess Macrophage Stimulant Activity and Drug Delivery Capabilities.
Topics: Antitubercular Agents; beta-Glucans; Biological Transport, Active; Caco-2 Cells; Carbohydrate Sequence; Cell Membrane Permeability; Cell Survival; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Humans; Intestinal Absorption; Lactic Acid; Macrophages; Molecular Sequence Data; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Stimulation, Chemical | 2015 |
Development and in vitro characterization of drug delivery system of rifapentine for osteoarticular tuberculosis.
Topics: Drug Delivery Systems; Lactic Acid; Microbial Sensitivity Tests; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Staphylococcus aureus; Surface Properties; Tuberculosis, Osteoarticular | 2015 |
Treatment of Staphylococcus aureus-induced chronic osteomyelitis with bone-like hydroxyapatite/poly amino acid loaded with rifapentine microspheres.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Chronic Disease; Delayed-Action Preparations; Drug Carriers; Durapatite; Lactic Acid; Microspheres; Osteomyelitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Rifampin; Staphylococcal Infections; Staphylococcus aureus | 2015 |
Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish.
Topics: Animals; Antitubercular Agents; Cell Survival; Cells, Cultured; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Lactic Acid; Macrophages; Male; Mice, Inbred C57BL; Mycobacterium tuberculosis; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Thioridazine; Tuberculosis; Zebrafish | 2016 |
Interfacial Fast Release Layer in Monodisperse Poly (lactic-co-glycolic acid) Microspheres Accelerates the Drug Release.
Topics: Delayed-Action Preparations; Drug Carriers; Drug Compounding; Kinetics; Lactic Acid; Microfluidic Analytical Techniques; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rifampin; Solubility; Surface Properties; Technology, Pharmaceutical | 2016 |
Highly efficient production of hyaluronic acid by Streptococcus zooepidemicus R42 derived from heterologous expression of bacterial haemoglobin and mutant selection.
Topics: Acetic Acid; Biomass; Fermentation; Glutamic Acid; Hemoglobins; Hyaluronic Acid; Lactic Acid; Maltose; Methylnitronitrosoguanidine; Rifampin; Streptococcus equi; Sucrose | 2016 |
Microencapsulation of rifampicin for the prevention of endophthalmitis: In vitro release studies and antibacterial assessment.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Endophthalmitis; Lactic Acid; Microbial Sensitivity Tests; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Staphylococcal Infections; Staphylococcus epidermidis; Time Factors | 2016 |
Rifapentine-loaded PLGA microparticles for tuberculosis inhaled therapy: Preparation and in vitro aerosol characterization.
Topics: Administration, Inhalation; Aerosols; Antitubercular Agents; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Drug Delivery Systems; Humans; Lactic Acid; Lung; Microscopy, Electron, Scanning; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin | 2016 |
[Fabrication of a new composite scaffold material for delivering rifampicin and its sustained drug release in rats].
Topics: Animals; Biocompatible Materials; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rifampin | 2016 |
A novel and simple preparative method for uniform-sized PLGA microspheres: Preliminary application in antitubercular drug delivery.
Topics: Animals; Antitubercular Agents; Centrifugation; Drug Delivery Systems; Intracellular Space; Lactic Acid; Macrophages; Mice; Microspheres; Particle Size; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RAW 264.7 Cells; Rifampin | 2016 |
Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics.
Topics: Adenosine Triphosphate; Antitubercular Agents; Drug Interactions; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Hep G2 Cells; Humans; Isoniazid; Lactic Acid; Membrane Potential, Mitochondrial; NAD; Pyrazinamide; Rifampin | 2017 |
[An experimental study on a slow-release complex with rifampicin-polylactic-co-glycolic acid-calcium
phosphate cement].
Topics: Bone Cements; Calcium Phosphates; Compressive Strength; Delayed-Action Preparations; Dental Cements; Lactic Acid; Materials Testing; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rifampin | 2016 |
Effect of bone-like hydroxyapatite/poly amino acid loaded with rifapentine microspheres on bone and joint tuberculosis in vitro.
Topics: Cell Differentiation; Cell Line, Tumor; Drug Carriers; Durapatite; Humans; Lactic Acid; Microbial Sensitivity Tests; Microspheres; Mycobacterium tuberculosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Tuberculosis, Osteoarticular; Wnt Signaling Pathway | 2017 |
Rifapentine-linezolid-loaded PLGA microspheres for interventional therapy of cavitary pulmonary tuberculosis: preparation and in vitro characterization.
Topics: Animals; Bronchoscopy; Dogs; Female; Lactic Acid; Linezolid; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Surface Properties; Tuberculosis, Pulmonary | 2017 |
Treatment of Francisella infections via PLGA- and lipid-based nanoparticle delivery of antibiotics in a zebrafish model.
Topics: Animals; Anti-Bacterial Agents; Fish Diseases; Francisella; Gram-Negative Bacterial Infections; Lactic Acid; Lipids; Nanoparticles; Oxolinic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Zebrafish | 2017 |
Biodegradable rifampicin-releasing coating of surgical meshes for the prevention of bacterial infections.
Topics: Animals; Anti-Bacterial Agents; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug Liberation; Female; Lactic Acid; Mice; Mice, Inbred C57BL; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polypropylenes; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Surgical Mesh; Surgical Wound Infection; Time Factors | 2017 |
Fabrication of Isoniazid/Rifampicin/Poly L-lactic Acid Donut-shaped Implants via Three Dimensional Printing Technique.
Topics: Delayed-Action Preparations; Isoniazid; Lactic Acid; Polyesters; Powders; Printing, Three-Dimensional; Prostheses and Implants; Rifampin | 2017 |
Antimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against
Topics: A549 Cells; Animals; Antitubercular Agents; Biocompatible Materials; Cell Death; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Compounding; Drug Delivery Systems; Drug Liberation; Humans; Isoniazid; Lactic Acid; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proton Magnetic Resonance Spectroscopy; RAW 264.7 Cells; Rifampin; Static Electricity; Surface Tension; Tuberculosis | 2018 |
Surface charge modulation of rifampicin-loaded PLA nanoparticles to improve antibiotic delivery in Staphylococcus aureus biofilms.
Topics: Anti-Bacterial Agents; Biofilms; Drug Delivery Systems; Drug Liberation; Lactic Acid; Microbial Sensitivity Tests; Nanoparticles; Polyesters; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Surface Properties | 2021 |
Sensitivity of wild-type and rifampicin-resistant O157 and non-O157 Shiga toxin-producing Escherichia coli to elevated hydrostatic pressure and lactic acid in ground meat and meat homogenate.
Topics: Drug Resistance, Bacterial; Hydrogen-Ion Concentration; Hydrostatic Pressure; Lactic Acid; Limit of Detection; Meat Products; Microbiota; Phenotype; Rifampin; Shiga-Toxigenic Escherichia coli; Temperature | 2021 |
Optimization of rifampicin encapsulation in PLGA polymeric reservoirs.
Topics: Emulsions; Lactic Acid; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Solvents | 2022 |
Bio-evaluation of poly(lactic-co-glycolic) acid nanoparticles loaded with radiolabelled rifampicin.
Topics: Drug Carriers; Glycols; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Tissue Distribution | 2023 |