lactic acid has been researched along with pyruvic acid in 2710 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 709 (26.16) | 18.7374 |
| 1990's | 555 (20.48) | 18.2507 |
| 2000's | 651 (24.02) | 29.6817 |
| 2010's | 649 (23.95) | 24.3611 |
| 2020's | 146 (5.39) | 2.80 |
| Authors | Studies |
|---|---|
| Coincon, M; Seah, SY; Sygusch, J; Wang, W | 1 |
| Coetzee, WA | 1 |
| Anezaki, T; Ibayashi, K; Miyatake, T; Yanagisawa, K | 1 |
| Hashimoto, T; Ito, M; Kuroda, Y; Miyazaki, M; Murakawa, K; Tayama, M | 1 |
| Bakkeren, JA; Feller, N; Ruitenbeek, W; Ruiter, J; Sengers, RC; Trijbels, JM; Wanders, RJ; Wijburg, FA | 1 |
| Cunniff, C; Keppler, K | 1 |
| Cooke, GM; Gardner, DK; Hunter, RH; Leese, HJ; Nichol, R | 1 |
| Camus, F; Chaussain, M; Defoligny, C; Eymard, B; Fardeau, M | 1 |
| Curi, R; Serrano, MA | 1 |
| Daniel, V; Drings, P; Eck, HP; Fätkenheuer, G; Mertens, T; Näher, H; Petzoldt, D; Pohl, C; Rosokat, H; Schrappe, M | 1 |
| Greene, LW; Wu, G | 1 |
| Brännström, M; Clague, N; Janson, PO; Jarrell, JF; Sevcik, M; Stuart, G | 1 |
| Andreu-Moliner, E; Ferrando, MD | 2 |
| Band, DM; Bruce, RC; Linton, RA; McLoughlin, P; Popham, P | 1 |
| Chow, JC; Jesse, BW | 1 |
| Dansereau, D; Gougoux, A; Vinay, P; Zan, N | 1 |
| Ayuso, MS; Ciprés, G; Martín-Requero, A; Parrilla, R; Rodríguez, A | 1 |
| Hirota, K; Ito, Y; Kuze, S; Miyahara, T; Naruse, T; Yamazaki, M | 1 |
| Drew, R; Knights, KM | 1 |
| Cohen, S; Gorman, JM; Klein, DF; Martinez, J; Papp, LA; Ross, D; Simon, J; Stein, JM | 1 |
| Jakobs, BS; Wanders, RJ | 1 |
| Bracht, A; Ishii-Iwamoto, EL; Yamamoto, NS | 1 |
| Asensi, M; Ferrero, JA; Furukawa, T; Gascó, E; Pallardó, FV; Sastre, J; Viña, J | 1 |
| Gougeon, R; Halter, JB; Hunt, R; Marliss, EB; Miles, PD; Purdon, C; Simantirakis, E; Vranic, M | 1 |
| Holm, S; Ström, D | 1 |
| Nikiforov, AA; Ostretsova, IB | 1 |
| Costa Rosa, LF; Curi, R; Cury, Y; Safi, DA | 1 |
| Husain, K; Jeevaratnam, K; Singh, R; Srivastava, DK; Sugendran, K | 1 |
| Ivashkevich, AA; Serebrovskaya, TV | 1 |
| Balon, TW; Stump, CS; Tipton, CM | 1 |
| Kawakami, Y; Kawase, M; Kondoh, Y; Ohmori, S | 1 |
| Kawase, M; Kondoh, Y; Ohmori, S | 1 |
| Igisu, H; Matsuoka, M | 1 |
| Gogoll, A; Helander, A | 1 |
| Bardet, J; Bonnefont, JP; Chretien, D; Cormier, V; Munnich, A; Nuttin, C; Parvy, P; Rötig, A; Rustin, P; Vassault, A | 1 |
| Kubota, M; Virkamäki, A; Yki-Järvinen, H | 1 |
| Babu, SR; Buckenmeyer, P; Knowlton, RG; Somani, SM | 1 |
| Armentano, LE | 1 |
| Beaver, WL; Cooper, CB; Cooper, DM; Wasserman, K | 1 |
| Halleck, MM; Kauffman, FC; Richburg, JH | 1 |
| Delehanty, JM; Imai, N; Liang, CS | 1 |
| Domenech, A; Gomez-Lucia, E; Goyache, J; Hernandez, FJ; Lopez, B; Orden, JA; Suarez, G | 1 |
| Aw, TY; Jones, DP; Kowalski, DP; Park, Y | 1 |
| Koike, A; Wasserman, K | 1 |
| Horai, S; Kondo, T; Mizuno, Y; Nakagawa-Hattori, Y; Yoshino, H | 1 |
| Landau, BR; Wahren, J | 1 |
| Horikawa, M; Komori, H; Kuroda, Y; Matsuishi, T; Naito, E; Ohtaki, E; Urabe, F; Yamashita, Y | 1 |
| Mills, GA; Walker, V | 1 |
| Bar-Tana, J; Hertz, R; Kalderon, B | 1 |
| Brasel, JA; Cooper, DM; Felsing, NE | 1 |
| Dalinghaus, M; Gerding, AM; Gratama, JW; Koers, JH; Kuipers, JR; Meuzelaar, JJ; Muskiet, FA | 1 |
| Aupetit, J; Bonnefont, JP; Charpentier, C; Chretien, D; Munnich, A; Rabier, D; Robinson, B; Rustin, P; Saudubray, JM; Vassault, A | 1 |
| Alemany, M; Argilés, MJ; Casado, J; Fernández-López, JA | 1 |
| Endo, Y; Kazama, M; Kobayashi, K; Miyajima, Y; Nakatani, T; Tahara, C; Tajimi, K; Tanaka, H | 1 |
| Forth, W; Kreppel, H; Reichl, FX | 1 |
| Gaevyĭ, MD; Ivashev, MN; Lavinskiĭ, NG; Nagornaia, GV; Pchelintseva, TR; Pyshnyĭ, VO; Vereshchagin, VK | 1 |
| Beyenburg, S; von Wersebe, O; Zierz, S | 1 |
| Bol'shakova, TN; Erlagaeva, RS; Gershanovich, VN; Grigorenko, IuA; Molchanova, ML | 1 |
| Flisińska-Bojanowska, A; Gill, J; Komosa, M | 2 |
| Nasu, T; Shibata, H; Zakimi, S | 1 |
| Cohnert, TU; Hartl, WH; Jauch, KW; Schildberg, FW; Wolfe, RR | 1 |
| Breitbart, H; Lardy, HA; Wehbie, R | 1 |
| Chang, GG; Chiou, SH; Huang, SM; Lee, HJ | 1 |
| Hillered, L; Persson, L | 1 |
| Asensi, M; Estrela, JM; Lopez-Rodas, A; Sastre, J; Viña, J | 1 |
| D'iachkova, GV; Kuznetsova, LS; Muradisinov, SO; Popkov, AV | 1 |
| Ihse, I; Larsson, J; Skullman, S | 1 |
| Field, CJ; Marliss, EB; Wu, GY | 2 |
| Brown, JJ; Whittingham, DG | 1 |
| Hild, R; Rexroth, W | 1 |
| Ding, XL; Long, YD; Luo, W; Xiao, LM; Yao, LY; Zhang, YL | 1 |
| Pugh, PA; Simpson, AC; Tervit, HR; Thompson, JG; Wright, RW | 1 |
| Fujishima, M; Ibayashi, S; Nakane, H; Okada, Y; Sadoshima, S | 1 |
| Mascord, D; Smith, J; Starmer, GA; Whitfield, JB | 1 |
| Carriero, D; Piomelli, S; Seaman, C; Tilton, WM | 1 |
| Maeda, N; Seiyama, A; Shiga, T | 1 |
| Giardina, B; Hassinen, IE; Lazzarino, G; Nuutinen, EM | 1 |
| Reddy, AT; Yellamma, K | 1 |
| Acosta, D; Davila, JC; Dorantes, A; Stavchansky, SA | 1 |
| Herndon, DN; Jahoor, F; Miyoshi, H; Wolfe, RR | 1 |
| Khovanskaia, TP; Morozova, TP; Razin, AS; Sokolov, EI; Velichkina, SV; Zaev, AP; Zhizhina, SA | 1 |
| Faulkner, A; Pollock, HT | 1 |
| Bavister, BD; McKiernan, SH; Tasca, RJ | 1 |
| Abe, K; Fujimura, H; Hirono, N; Kameyama, M; Mezaki, T; Nishikawa, Y; Nishitani, N; Yorifuji, S | 1 |
| Almond, MK; Cohen, RD; Flynn, G; Iles, RA; Smith, A | 1 |
| Cárdenas, P; Chacín, J; Hernández, I; Lobo, P | 1 |
| Gabreëls, FJ; Renier, WO; Ruitenbeek, W; Sengers, RC; ter Laak, HJ; Thijssen, HO; van Hellenberg Hubar, JL | 1 |
| Baturin, AA; Marchenko, LF; Terent'eva, EA | 1 |
| Hillered, L; Kotwica, Z; Ungerstedt, U | 1 |
| Conricode, KM; Ochs, RS | 1 |
| Böttcher, H; Engel, S; Fürst, P; Nittinger, J | 1 |
| Angerås, U; Fischer, JE; Hall-Angerås, M; Hasselgren, PO; James, H; Wagner, KR | 1 |
| Hashimoto, T; Ito, M; Kuroda, Y; Naito, E; Saijo, T; Takeda, E | 1 |
| Bavister, BD; Seshagiri, PB | 1 |
| Gill, J | 1 |
| Larralde, J; Martínez, JA; Portillo, MP | 1 |
| Chang, GG; Chiou, SH; Huang, SM | 1 |
| Felipe, A; Pastor-Anglada, M; Remesar, X | 1 |
| Ekroth, R; Joachimsson, PO; Ronquist, G; Svedjeholm, R; Svensson, S; Tydén, H | 1 |
| Bohnensack, R; Fritz, S | 1 |
| Hale, PJ; Nattrass, M | 2 |
| Ardawi, MS; Kateilah, SM; Majzoub, MF; Newsholme, EA | 1 |
| Aasly, J; Borud, O; Lindal, S; Mellgren, SI; Torbergsen, T | 1 |
| Javed, MH | 1 |
| Leese, HJ; Lenton, EA | 1 |
| Heine, A; Heitefuss, S; Seifert, HS | 1 |
| Deaciuc, IV; Spitzer, JA | 1 |
| Benzi, L; Brunetti, P; Cecchetti, P; Di Carlo, A; Di Cianni, G; Giannarelli, R; Gregorio, F; Marchetti, P; Navalesi, R; Villani, G | 1 |
| Cranmer, SL; Halestrap, AP; Poole, RC | 1 |
| Kim, E; Na, KJ | 1 |
| Licciardi, A; Morici, G | 1 |
| Charlton, VE; Harding, JE | 1 |
| Govindarajulu, P; Kumari, TM | 1 |
| Galan Galán, F; Garrido Peralta, M; Montoya García, M; Moruno García, R; Murillo del Castillo, C; Oliván Martínez, J; Pérez Cano, R | 1 |
| Davies, S; Dillon, D; Fyer, AJ; Goetz, RR; Gorman, JM; Klein, DF; Liebowitz, MR | 1 |
| de Groot, CJ; Feller, N; Wanders, RJ; Wijburg, FA | 1 |
| Dragićević, L; Kostić, MM; Müller, M; Rapoport, SM; Zirković, R | 1 |
| Horimi, T; Kuwao, F; Mizobuchi, N; Morita, S; Takahashi, I; Takeda, I; Takemura, T | 1 |
| Fry, M; Pudney, M; Webb, E | 1 |
| Feller, N; Przyrembel, H; Ruitenbeek, W; Scholte, HR; Sengers, RC; Trijbels, JM; Wanders, RJ; Wijburg, FA | 1 |
| Capaldi, R; Chow, W; Glerum, DM; Lightowlers, R; Petrova-Benedict, R; Robinson, BH | 1 |
| Dargel, R; Dietrich, N; Haufe, CC; Schulze, HP | 1 |
| Agius, L; Alberti, KG; Peak, M | 1 |
| Cavallini, L; Rigobello, MP; Valente, M | 1 |
| Björkman, O; Eriksson, LS; Nyberg, B; Wahren, J | 1 |
| Gavin, JR; Karl, IE; Levy, J | 1 |
| Nishizawa, K; Shimada, M; Tanaka, K | 1 |
| Gábor, D; Gregorová, H; Laca, L; Ondrus, P | 1 |
| Ayuso, MS; González-Manchón, C; Parrilla, R | 1 |
| Cathcart, S; Fisher, BM; Goldberg, A; Herrick, AL; McColl, KE; Moore, MR | 1 |
| Foster, PM; Reader, SC | 1 |
| Agius, L; Peak, M | 1 |
| Mengual, R; Schlageter, MH; Sudaka, P | 1 |
| Liedtke, AJ; Nellis, SH; Renstrom, B | 1 |
| Cowper, KB; Currin, RT; Dawson, TL; Lemasters, JJ; Lindert, KA; Thurman, RG | 1 |
| Radhaiah, V; Rao, KJ | 1 |
| Gardner, DK; Leese, HJ | 1 |
| Ura, T | 1 |
| Sahlin, K | 1 |
| Chang, GG; Chiou, SH; Lee, HJ | 1 |
| Di Lisa, F; Giamberardino, MA; Maccari, F; Menabo, R; Pieralisi, G; Ripari, P; Siliprandi, N; Vecchiet, L | 1 |
| Gross, W; Michels, W; Müller, B; Nöschel, H; Reiber, W; Schröder, S | 1 |
| Alexander, K; Goller, B; Grote, R; Maass, U | 2 |
| Jakobs, C; Joenje, H; Schoonen, WG; van der Klei-van Moorsel, JM; Wanamarta, AH | 1 |
| Kenney, R; Parrish, A; Tomacelli, C; Zikira, M | 1 |
| Cryer, HG; Cué, JI; Mavroudis, C; Polk, HC; Richardson, JD; Roberts, AM; Yu, J | 1 |
| Isselhard, W; Kiuchi, T; Ozawa, K; Shimahara, Y | 1 |
| Hillered, L; Nilsson, P; Pontén, U; Ungerstedt, U | 1 |
| Bakay, RA; Sweeney, KM; Wood, JH | 1 |
| Acad, BA; Dvir, S; Furman, E; Kedem, J; Sonn, J | 1 |
| Dhananjaya Naidu, M; Ravindran, K; Swami, KS | 1 |
| Allgén, LG; Dimberg, M; Norlén, H | 1 |
| Gianotti, M; Palou, A; Roca, P | 1 |
| Kasinathadurai, R; Ramalingam, K | 1 |
| Fernandez-Romero, JM; Luque de Castro, MD; Valcarcel, M | 1 |
| Andersen, NE; Gyring, J; Hansen, AJ; Laursen, H; Siesjö, BK | 1 |
| Van Scott, EJ; Yu, RJ | 1 |
| Den Boer, JA; Klompmakers, AA; van Lint, LE; Westenberg, HG | 1 |
| Blaise, G; Boulanger, Y; Cardoso, M; Gougoux, A; Léveillé, M; Noël, J; Prud'homme, M; Vinay, P; Vinet, B | 1 |
| Matsuno, T | 2 |
| Baverel, G; Martin, G; Michoudet, C | 1 |
| Baumgartner, ER; Krägeloh-Mann, I; Nothjunge, J; Suormala, TM | 1 |
| Ikeda, T; Inada, Y; Matsui, K; Morimoto, F; Takeda, S; Tomaru, T | 1 |
| Akanji, AO; Hockaday, TD; Humphreys, S; Thursfield, V | 1 |
| Barlow, J; Devlin, JT; Horton, ES | 1 |
| Erecinska, M; Meglasson, MD; Nelson, D; Smith, KM | 1 |
| Felber, JP; Ferrannini, E; Jequier, E; Locatelli, L | 1 |
| Aynsley-Green, A; Boyes, S; Schwartz, RM | 1 |
| Anderson, VE; LaReau, RD | 1 |
| Aoki, T; Benn, JJ; Bozzard, SJ; Gerich, J; Kelley, D; Mitrakou, A; Sonksen, PH; Sorensen, J | 1 |
| Beuers, U; Jungermann, K; Küster, J | 1 |
| Wendt, IR | 1 |
| Kitamura, S; Miyai, K; Schölmerich, J | 1 |
| Odinak, MM; Zaporoshchenko, IA | 1 |
| Gorozhanskaia, EG; Gromova, EG; Sviridova, SP | 1 |
| Saito, H; Uchijima, Y; Yoshida, K | 1 |
| Galione, A; Hopps, V; Sorrentino, MC; Vetri, P; Woodrow, ME | 1 |
| Bhattacharyya, A; Hoskins, DD; Vijayaraghavan, S | 1 |
| Badawy, AA; Dando, TG; Kirby, A; Morgan, CJ; Thomas, DR | 1 |
| Mascord, D; Rogers, J; Smith, J; Starmer, GA; Whitfield, JB | 1 |
| Fischer, B; Holm, E; Jacob, S | 1 |
| Appleton, DR; Dunlop, W; Prentice, A; Vadgama, P | 1 |
| Campbell, K; Frewen, TC; Han, VK; Sumabat, WO; Tiffin, N | 1 |
| Berry, MN; Gregory, RB | 1 |
| Kainulainen, H; Ruskoaho, H; Takala, TE; Virtanen, P | 1 |
| Lange, H; Rieke, H; Sonntag, H; Stephan, H | 1 |
| Amma, MK; Majumdar, S; Morshed, KM; Nagpaul, JP | 1 |
| Gückel, F; Hild, R; Rexroth, W; Semmler, W; Stadtlander, M; van Kaick, G; Weicker, H | 1 |
| Alexander, K; Goller, B; Grote, R; Maass, U; Nehmiz, G; Schneider, B | 1 |
| Guliamov, DS; Kim, NP; Maevskii, EI; Ovchinnikov, IV | 1 |
| Jerusalem, F; Meessen, S; Zierz, S | 1 |
| Cerbón, J; Cerbón-Ambriz, J; González, E; Rojkind, M | 1 |
| Buc, HA; Claeyssens, S; Lavoinne, A; Matray, F; Pinosa, M | 1 |
| Pall, ML; Robertson, CK | 1 |
| Harigaya, Y; Hirai, S; Okamoto, K; Sato, T; Shoji, M | 1 |
| Balkovetz, DF; Ganapathy, V; Leibach, FH; Mahesh, VB | 1 |
| Mounier, J; Sansonetti, PJ | 1 |
| Lin, S; Raabe, W | 1 |
| Bieger, WP; Michel, G; Schwarz, W | 1 |
| Allignet, E; Junco, E; Lemieux, C; Lemieux, G; Perez, R | 1 |
| Gries, FA; Hübinger, A; Lehmann, E; Ridderskamp, I | 1 |
| Bygrave, FL; Taylor, WM; Van de Pol, E | 1 |
| Ingvar, M; Siesjö, BK; Wieloch, T | 1 |
| Blanco, A; Burgos, C; Coronel, CE; Gallina, FG; Gerez de Burgos, NM | 1 |
| Mörikofer-Zwez, S; Stoecklin, FB; Walter, P | 1 |
| Abdel Latife, HA; Daabees, AY; el Domiaty, NA; Hilmy, AM | 1 |
| Hall, JE; Sechelski, J; Seed, JR | 1 |
| Aprille, JR; Tullson, PC | 1 |
| Katsumata, Y; Mori, S; Murakami, K; Takabayashi, A; Yoshino, M | 1 |
| Buhl, H; Krause, P; Rogos, R | 1 |
| Bryła, J; Zabłocki, K | 1 |
| Drejer, J; Hertz, L; Schousboe, A | 1 |
| Grunewald, RW; Jans, AW; Kinne, RK | 1 |
| Astiz, ME; Kim, YB; Rackow, EC; Weil, MH | 1 |
| Fujii, K; Fujishima, M; Ishitsuka, T; Nishimura, Y; Oshima, M; Sadoshima, S; Yao, H | 1 |
| Gabbay, RA | 1 |
| Floka, EI | 1 |
| Whitmer, JT | 1 |
| Dröge, W; Mihm, S | 1 |
| Hladovec, J | 1 |
| Appenzeller, O; Rosenberg, GA | 1 |
| Carpinelli, AR; Dufrane, SP; Garcia-Morales, P; Malaisse, WJ; Malaisse-Lagae, F; Mathias, PC; Sener, A; Valverde, I | 1 |
| Laustiola, K | 1 |
| Bünger, R | 1 |
| Lardy, HA; Warnette-Hammond, ME | 1 |
| Cabello, MA; Feliu, JE; Mojena, M; Monge, L; Ortega, JL; Samper, B | 1 |
| Reinacher, M; Schering, B; Schoner, W | 1 |
| Baudet, A; Goodyer, P; Robinson, BH; Ward, J | 1 |
| Hodson, AW; Skillen, AW; Stappenbeck, R | 1 |
| Marsac, C; Stansbie, D; Wallace, SJ | 1 |
| Davies, AO | 1 |
| Ogata, M; Yagi, T | 1 |
| Cook, RA; Lang, VJ; Leystra-Lantz, C | 1 |
| Vaĭchekonis, VI | 1 |
| Takagi, D; Takeyama, N; Tanaka, T | 1 |
| Castillo-Olivares, JL; Cienfuegos, JA; Codoceo, R; Herrera, J; Mora, NP; Navidad, R; Pereira, F; Ratia, T; Tendillo, FJ | 1 |
| Bohm, J; Graubaum, HJ; Lohse, W; Seifert, R; Staffa, G; Warnke, H | 1 |
| Katayama, T; Kitakado, Y; Sakai, Y; Takada, Y; Tanaka, K; Tokunaga, Y; Ueda, J; Yamaguti, M; Yamamoto, Y; Zaima, M | 1 |
| Patel, TB | 1 |
| Hopkins, LC; Rosing, HS | 1 |
| Chandramouli, V; Kosugi, K; Kumaran, K; Landau, BR; Schumann, WC; Scofield, RF | 1 |
| Alberti, KG; Dick, DJ; Sherratt, HS; Turnbull, DM; Wilson, L | 1 |
| Chin, NW; Hitti, IF; Lanks, KW | 1 |
| Michenfelder, JD; Milde, JH; Milde, LN | 1 |
| Haas, RH; Merritt, TA; Rice, MA; Trauner, DA | 1 |
| Brown, DJ; Dehring, AF; Engle, MJ | 1 |
| Beaver, WL; Wasserman, K; Whipp, BJ | 1 |
| Basford, RE; Kyriazi, HT | 1 |
| Berdanier, CD; Wander, RC | 1 |
| Snow, TR | 1 |
| Olson, MS; Patel, TB | 2 |
| Alberti, KG; Johnson, GA; Johnston, DG; Millward-Sadler, GH; Mitchell, J; Wright, R | 1 |
| Heidland, A; Hörl, WH; Riegel, W | 1 |
| Brosnan, JT; Forsey, RG; Reid, K | 1 |
| Dahms, B; Hoppel, CL; Kerr, DS; Roessmann, U | 1 |
| Fujii, K; Fujishima, M; Ishitsuka, T; Kusuda, K; Sadoshima, S; Tamaki, K; Yao, H | 1 |
| Clary, GL; Guynn, RW | 1 |
| Breningstall, GN | 1 |
| Foster, PM; Williams, J | 1 |
| Berry, SA; Ho, L; Kerr, DS; Lusk, MM; Patel, MS | 1 |
| Bennegård, K; Bylund-Fellenius, AC; Elander, A; Lundgren, F; Lundholm, K; Scherstén, T | 1 |
| Gougoux, A; Lopez-Novoa, JM; Rengel-Aranda, M; Vinay, P | 1 |
| Basu, SK; Batabyal, SK; Dey, SN; Dolui, AK; Gupta, M; Mukherjee, S | 1 |
| Jeevarathinam, K; Mukhopadhyay, S; Ray, US; Selvamurthy, W; Thakur, L | 1 |
| Halestrap, AP; Poole, RC | 1 |
| Mechír, E; Mechírová, E | 1 |
| Bhuta, S; Breda, MA; Chang, PA; Drinkwater, DC; Laidig, CA; Laks, H; Sadeghi, AM; Wu, A | 1 |
| Fujii, K; Fujishima, M; Ishitsuka, T; Nakatomi, Y; Ooboshi, H; Sadoshima, S | 1 |
| Acker, H; Carlsson, J | 1 |
| González-Manchón, C; Parrilla, R; Sánchez-Ayuso, M | 1 |
| Higashimoto, Y; Himeno, S; Kashimura, M; Kawamoto, H; Kuroshima, T; Okuno, M; Tarui, S; Tsuji, K; Yamasaki, Y | 1 |
| Kliegman, RM | 1 |
| Ikai, I; Morimoto, T; Ozaki, N; Ozawa, K; Shimahara, Y; Tanaka, A; Tokunaga, Y; Wakashiro, S | 1 |
| Adams, CE; Mortimore, GE; Wert, JJ | 1 |
| Barnie, A; Liu, PP; McLaughlin, PR; Ruddy, TD; Seawright, SJ; Shumak, SL; Zinman, B | 1 |
| Bartlett, SM; Gibbons, GF | 1 |
| Ambrosio, G; Angelini, C; Attisano, T; Brevetti, G; Chiariello, M; Ferulano, G; Nevola, E; Policicchio, A; Rossini, A; Siliprandi, N | 1 |
| Ikuta, F; Nakamura, N; Ohama, E | 1 |
| Noakes, TD; Peters Futre, EM; Raine, RI; Terblanche, SE | 1 |
| Cooke, NJ; Greenstone, M; Home, PD; Kruszynska, YT | 1 |
| Brockman, RP | 2 |
| Cooper, DK; Isaacs, S; Morrell, D; Novitzky, D | 1 |
| Edlund, GL; Halestrap, AP | 1 |
| Bachelard, HS; Cox, DW | 1 |
| Aoki, T; Hobara, T; Imamura, A; Iwamoto, S; Kawamoto, T; Kobayashi, H; Miyazaki, Y; Ogino, K; Sakai, T; Takano, T | 1 |
| Angus, PW; Mihaly, GW; Morgan, DJ; Smallwood, RA | 1 |
| Cheeseman, AJ; Clark, JB | 1 |
| Hashimoto, S; Kitaguchi, M; Nishikawa, Y; Takahashi, M; Tarui, S; Tatsumi, C; Yorifuji, S | 1 |
| Bachelard, HS; Cox, DW; Garofalo, O | 1 |
| Nakada, I | 1 |
| Kaneoka, T; Shimizu, H; Shirakawa, K; Taguchi, S | 1 |
| Ericsson, M; Kaijser, L; Walldius, G | 1 |
| Agius, L | 1 |
| Gieracz-Nazar, A; Hasiec, T; Kawiak, W; Nowicki, J; Stelmasiak, Z; Wróblewski, L | 1 |
| Brown, BI; Burke, BA; Tuchman, M; Ulstrom, RA | 1 |
| Dröge, W; Eck, HP; Kriegbaum, H; Mihm, S | 1 |
| Lanks, KW | 2 |
| Moffitt, EA; Sethna, DH | 1 |
| Espinal, J; Ross, BD; Silva, P | 1 |
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| Benz, AM; Izumi, Y; Katsuki, H; Zorumski, CF | 1 |
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| Blanco, CE; Maertzdorf, WJ; van der Hoeven, MA | 2 |
| Hamlin, RL; Jiang, Z; Rath, DP; Robitaille, PM; Tong, X; Zhu, H | 1 |
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| Engelbrecht, V; Gärtner, J; Lenard, HG; Lohmeier, K; Schürmann, M; Wendel, U | 1 |
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| Killick, SR; Leese, HJ; Maguiness, SD; Partridge, RJ; Rutherford, AJ; Tay, JI | 1 |
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| Dev, R; Gupta, RK; Husain, M; Poptani, H; Roy, R; Sharma, S | 1 |
| Scofield, MA; Shimozono, M; Wangemann, P | 1 |
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| Bünger, R; Lasley, RD; Martin, BJ; Mentzer, RM; Valdivia, HH | 1 |
| Agarwal, A; Pandey, VC; Tripathi, LM | 1 |
| Baio, DL; Cunningham, CC; Czyz, CN; Ivester, P; Van Horn, CG | 1 |
| Drewes, LR; Enerson, BE; Gerhart, DZ; Leino, RL; Zhdankina, OY | 1 |
| Beaudry, M; el Abida, K; Mengual, R; Mouaffak, N; Rieu, M | 2 |
| Deck, LM; Gomez, MS; Hunsaker, LA; Makler, MT; Piper, RC; Royer, RE; Vander Jagt, DL | 1 |
| Beylot, M; Brunengraber, H; Diraison, F; Large, V | 1 |
| Araga, S; Nakashima, K; Okada, H; Takeshima, T | 1 |
| Graver, M; Metz, HN; Nikolic, SD; Palazzo, RS; Rao, PS; Rao, SK; Wilson, DW | 1 |
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| Adler, L; Ansell, R; Gustafsson, L; Larsson, C; Påhlman, IL; Rigoulet, M | 1 |
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| Liu, J; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Coffe, V; Hernández-Muñoz, R; Salceda, R; Vilchis, C | 1 |
| Kuroda, Y; Saijo, T | 1 |
| Benedetti, G; Capristo, E; De Gaetano, A; Gasbarrini, G; Greco, AV; Mingrone, G | 1 |
| Moiseenok, AG; Omelyanchik, SN; Slyshenkov, VS; Trebukhina, RV; Wojtczak, L | 1 |
| Higashino, K; Hiroishi, K; Moriwaki, Y; Nakano, T; Ohata, H; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| Higashino, K; Hiroishi, K; Moriwaki, Y; Nakano, T; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| Lawford, HG; Rousseau, JD | 1 |
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| Blackburn, BJ; Corbin, I; Novak, M; Simcoff, R | 1 |
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| Arp, S; Chan, A; Gold, R; Pflughaupt, KW; Reichmann, H; Toyka, KV | 1 |
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| Hillered, L; Persson, L; Valtysson, J | 1 |
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| Cohen, G; Ikonomidis, JS; Li, RK; Merante, F; Mickle, DA; Rao, V; Robinson, BH; Shiono, N; Shirai, T; Tumiati, LC; Weisel, RD | 1 |
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| Chamblee, BB; Deck, LM; Hernandez, VM; Hunsaker, LA; Makler, MT; Malone, RR; Piper, RC; Royer, RE; Torres, JE; Vander Jagt, DL | 1 |
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| Bracht, A; Ishii-Iwamoto, EL; Kemmelmeier, FS; Nascimento, EA; Tonon, FA | 1 |
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| Ching, MS; Ghabrial, H; Gow, PJ; Jin, CJ; Morgan, DJ; Shulkes, A; Smallwood, RA; Treepongkaruna, S | 1 |
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| Buckels, JA; Harrison, JD; Iriyama, K; Mayer, AD; McMaster, P; Miki, C; Suzuki, H | 1 |
| Becker, BF; Conzen, PF; Heindl, B; Szekely, A; Zahler, S | 1 |
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| Brandt, L; Nilsson, OG; Säveland, H; Ungerstedt, U | 1 |
| Brooks, GA; Brown, MA; Butz, CE; Dubouchaud, H; Sicurello, JP | 1 |
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| Chesley, A; Heigenhauser, GJ; Jones, NL; Matsos, MP; Parolin, ML; Spriet, LL | 1 |
| Bardouniotou, H; Delivoria-Ioannidou, V; Kazi, D; Roussos, C; Routsi, C; Zakynthinos, S | 1 |
| Dominguez, LJ; Ofenstein, JP; Sarnaik, AP; Sowers, JR | 1 |
| Bou-Hanna, C; Jarry, A; Laboisse, CL; Le Goffe, C; Vallette, G | 1 |
| Drewes, LR; Ishihara, H; Wang, H; Wollheim, CB | 1 |
| Amado, CB; Bracht, A; Fedatto Júnior, Z; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Panerari, AD; Vicentini, GE | 1 |
| Cavaliere, F; Meo, F; Scapigliati, A; Schiavello, R; Sciarra, M | 1 |
| Gardner, DK; Lane, M | 1 |
| Deutz, NE; Does, JD; Engelen, MP; Schols, AM; Wouters, EF | 1 |
| Cabrera, ME; Kalhan, SC; Saidel, GM | 1 |
| Becker, BF; Heindl, B | 1 |
| Takahashi, N; Yamada, T | 1 |
| de L Costello, AM; Land, JM; Manandhar, DS; Pal, DK; Patel, N; Rajbhandari, S | 1 |
| Brown, SD; Letarte, PB; Marion, DW; Puccio, AM | 1 |
| Hara, M; Nara, I; Saito, I; Saruta, K; Shiogai, T | 1 |
| Halcak, L; Hola, J; Holoman, M; Kalnovicova, T; Pechan, I; Rendekova, V; Zahorec, R | 1 |
| Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| Docampo, R; Vanderheyden, N; Wong, J | 1 |
| Fitts, RH; Grichko, VP; Heywood-Cooksey, A; Kidd, KR | 1 |
| Bollaert, PE; Gelot, AM; Larcan, A; Levy, B; Nabet, P; Sadoune, LO | 1 |
| Mizock, BA | 1 |
| Aquilani, R; Arrigoni, N; Boschi, F; Catapano, M; Dossena, M; Fugazza, G; Guarnaschelli, C; Iadarola, P; Pastoris, O; Viglio, S | 1 |
| Eagen, CK; Fisher, NM; Horvath, PJ; Leddy, JJ; Pendergast, DR | 1 |
| Kneer, N; Lardy, H | 1 |
| Gerasimov, IG; Plaksina, EN | 1 |
| Cieslar, JH; Dobson, GP | 2 |
| Bråthe, A; Hassel, B | 1 |
| Heigenhauser, GJ; Hollidge-Horvat, MG; Hultman, E; Jones, NL; Parolin, ML; Spriet, LL | 1 |
| Greene, AK; Guzel-Seydim, Z; Seydim, AC | 1 |
| Chen, SH; Cheng, FC; Lee, CW; Tsai, TH; Yan, DY; Yang, LL | 1 |
| Berezovskaia, OP; Desiatnichenko, KS; Kuznetsova, LS; Shevtsov, VI | 1 |
| Khurana, NK; Niemann, H | 1 |
| Beconi, MT; Cetica, PD; Dalvit, GC; Pintos, LN | 1 |
| Miwa, I; Okinaka, M; Tanigawa, K; Taniguchi, S | 1 |
| Armstrong, VL; Clulow, J; Jones, RC; Murdoch, RN | 1 |
| Cha, KY; Chung, HM; Hwang, WS; Ko, JJ; Lee, BC; Lee, ES; Lim, JM; Park, SE | 1 |
| Allen, JC; Kahn, AM; Lichtenberg, DS; Seidel, CL; Song, T; Zhang, S | 1 |
| Baldwin, RL; McLeod, KR | 1 |
| Gready, JE; Harvey, PJ; Le Couteur, DG; McLean, AJ; Yin, Z | 1 |
| Al Makdessi, S; Dartsch, PC; Kimmel, R; Schiek, D; Schmahl, FW; Sweidan, H; Wolburg, H | 1 |
| Fisher, SJ; Gougeon, R; Kreisman, SH; Manzon, A; Marliss, EB; Morais, JA; Nessim, SJ; Vranic, M | 1 |
| Comte, B; Poirier, M; Rosiers, CD; Vincent, G | 1 |
| Ah Mew, N; Arsenault, M; Halter, JB; Kreisman, SH; Marliss, EB; Nessim, SJ; Vranic, M | 1 |
| Aadahl, P; Bäckström, T; Myhre, HO; Norgren, L; Saether, OD; Ungerstedt, U | 1 |
| Faelli, A; Gastaldi, G; Orsenigo, MN; Tosco, M | 1 |
| Bentzer, P; Davidsson, H; Grände, PO | 1 |
| Harano, M; Kawada, N; Ryozo, N; Takakura, N; Tanaka, N; Tsuge, H | 1 |
| Belin, MF; Bellier, JP; Jacquemont, B; Perret-Liaudet, A; Prod'hon, C; Sacchettoni, S | 1 |
| Chen, CJ; Chen, WY; Cheng, FC; Kuo, JS; Liao, SL; Lin, NN | 1 |
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| Lundberg, G; Olofsson, P; Sundberg, CJ; Swedenborg, J; Ungerstedt, U; Wahlberg, E | 1 |
| Bhoola, SM; DiGirolamo, M; Isaacs, SD; Kokko, JP; Tuvlin, JA; Umpierrez, GE | 1 |
| Al-Rawi, PG; Gupta, AK; Hutchinson, DB; Hutchinson, PJ; Kett-White, R; Kirkpatrick, PJ; Maskell, LB; O'Connell, MT; Pickard, JD; Richards, HK | 1 |
| Chau, TT; Chuong, LV; Day, NP; Hien, TT; Holloway, P; Loc, PP; Mai, NT; Phu, NH; Sinh, DX; White, NJ | 1 |
| Kari, A; Ruokonen, E; Suistomaa, M; Takala, J | 1 |
| Heigenhauser, GJ; Jones, NL; Spriet, LL; St Amand, TA | 1 |
| Fryer, MW; Posterino, GS | 1 |
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| Arbour, R; Esparis, B | 1 |
| Grande, PO; Möller, AD; Nordström, CH; Ungerstedt, U | 1 |
| de Graaf, AA; Eggeling, L; Möllney, M; Petersen, S; Sahm, H; Wiechert, W | 1 |
| Katz, A; Shomrat, A; Weinstein, Y | 1 |
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| Cechowska-Pasko, M; Pałka, J | 1 |
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| Mellergård, P; Nordström, CH; Reinstrup, P; Ståhl, N; Ungerstedt, U; Uski, T | 1 |
| Mokuda, O; Sakamoto, Y | 1 |
| Darbin, O; Grellier, P; Lonjon, M; Michiels, JF; Negrin, J; Quentien, MH; Risso, JJ; Rostain, JC | 1 |
| Borgström, MK; Edwardsson, S; Sullivan, A; Svensäter, G | 1 |
| Boobis, L; Constantin-Teodosiu, D; Greenhaff, P; Hultman, E; Tsintzas, K; Williams, C | 1 |
| Brunengraber, H; Comte, B; Darvish, A; des Rosiers, C; Huang, H; Kerwin, T; Panchal, AR; Stanley, WC | 1 |
| Bassenge, E; Bünger, R; Schwemmer, M; Sommer, O | 1 |
| Bjerre, P; Schulz, MK; Tange, M; Wang, LP | 1 |
| Deutz, NE; Does, JD; Engelen, MP; Gosker, HR; Schols, AM; Wouters, EF | 1 |
| Imon, Y; Kajima, T; Katayama, S; Mimori, Y; Nakamura, S; Ohshita, T; Oka, M; Watanabe, C; Yamaguchi, S | 1 |
| Choi, C; Kim, DI; Kim, HS; Sunwoo, IN | 1 |
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| Dess, DM; Diaz-Cueto, L; Jones, BH; Jorgez, CJ; Kopf, GS; Merdiushev, T; Moss, SB; Storey, BT; Travis, AJ | 1 |
| Altherr, J; Brinkmann, A; Georgieff, M; Jauch, KW; Matejovic, M; Radermacher, P; Träger, K; Vlatten, A; Vogt, J; Wachter, U; Zülke, C | 1 |
| Efendic, S; Fisher, SJ; Giacca, A; Lickley, HL; Shi, ZQ; Vranic, M | 1 |
| O'Regan, MH; Phillis, JW; Ren, J | 1 |
| Gandhi, AP; Gardner, DK; Krisher, RL; Lane, M | 1 |
| Bavister, BD; Ji, W; Zheng, P | 1 |
| Cohen, DM; Goodwin, GW; Taegtmeyer, H | 1 |
| Aoki, K; Badr, A; Tibbs, R; Yin, W; Zhang, J | 1 |
| Bünger, R; Chung, SJ; Kang, IJ; Kang, YH; Park, JH | 1 |
| Abbe, K; Takahashi, N; Takahashi-Abbe, S; Tamazawa, Y; Yamada, T | 1 |
| Grände, PO; Möller, AD | 1 |
| Mukoyama, S; Oikawa, T; Soda, K | 1 |
| Gardner, DK; Lane, M; Pool, TB | 1 |
| Jahan, I; Ng, R; Thornalley, PJ | 1 |
| Lang, HJ; Obrosova, IG; Stevens, MJ | 1 |
| Corradi, D; D'Adda, T; Giordano, G; Melissari, M | 1 |
| Decking, UK; Deussen, A; Preckel, B; Schrader, J; Skwirba, S; Thämer, V; Zimmermann, MF | 1 |
| Furuya, A; Kashimoto, S; Kumazawa, T; Kume, M | 1 |
| Elliott, JL; Kirk, K; Saliba, KJ | 1 |
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| Bradnock, TJ; Dabos, KJ; Hayes, PC; Nelson, LJ; Parkinson, JA; Plevris, JN; Sadler, IH | 1 |
| Leibfritz, D; Richter-Landsberg, C; Zwingmann, C | 1 |
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| Akimoto, LS; Bazotte, RB; Lopes, G; Pedrinho, SR | 1 |
| Darbin, O; Lonjon, M; Negrin, J; Palmier, B; Risso, JJ | 1 |
| Gardner, DK; Lane, M; O'Donovan, MK; Seidel, GE; Squires, EL | 1 |
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| Ishii, N; Yanase, S; Yasuda, K | 2 |
| Aggarwal, R; Autry, A; Bok, R; Chang, S; Chen, HY; Ferrone, M; Gordon, JW; Kurhanewicz, J; Larson, PEZ; Li, Y; Mammoli, D; Milshteyn, E; Nelson, S; Park, I; Slater, JB; Van Criekinge, M; Vigneron, DB; Xu, D | 1 |
| Aarsand, AK; Asland, B; Bartlett, WA; Boned, B; Braga, F; Carobene, A; Corte, Z; Coskun, A; Díaz-Garzón, J; Fernández-Calle, P; Fernández-Fernández, P; González-Lao, E; Jonker, N; Marqués-García, F; Minchinela, J; Perich, C; Ricós, C; Roraas, T; Sandberg, S; Simón, M | 1 |
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| Kang, K; Kang, WJ; Lian, KQ; Tan, XX; Wang, W; Zhang, HY | 1 |
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| Alves, DSMM; Costa, TL; Isac, E; Lima, NF; Lino Junior, RS; Picanço, GA; Silva, LD; Vinaud, MC | 1 |
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| Cox, BL; Eliceiri, KW; Erickson-Bhatt, S; Fain, SB; Ludwig, KD; Macdonald, EB; Ponik, SM; Squirrell, JM; Swader, R; Szulczewski, JM | 1 |
| Aoki, J; Fujita, S; Haneda, T; Hayashi, A; Imai, T; Inoue, A; Ishii, M; Kayama, H; Kida, T; Kikuta, J; Kimura, I; Maeda, Y; Mimuro, H; Morita, N; Nabeshima, R; Okada, N; Okumura, R; Takeda, K; Umemoto, E | 1 |
| Bartesaghi, S; Beg, M; Betz, MJ; Enerbäck, S; Foyn, H; Haufs-Brusberg, S; Heglind, M; Jedrychowski, MP; Kanduri, C; Lidell, ME; Ma, H; Mondal, T; Naumann, J; Nilsson, D; Palmgren, H; Peng, XR; Pfeifer, A; Subhash, S; Sukonina, V; Taskén, K; Zhang, W | 1 |
| Crosier, AE; Keefer, CL; Weiner, HS | 1 |
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| Bankson, JA; Fuentes, D; Kundra, V; Larson, PEZ; Vigneron, DB; Walker, CM | 1 |
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| Funk, AM; Hever, T; Khemtong, C; Malloy, CR; Maptue, NR; Sherry, AD; Wen, X | 1 |
| Breukels, V; Heerschap, A; Kobus, T; Lenting, K; Peeters, TH; Scheenen, TWJ; Veltien, A | 1 |
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| Beer, R; Gaasch, M; Helbok, R; Ianosi, B; Kofler, M; Lindner, A; Pfausler, B; Rass, V; Rhomberg, P; Schiefecker, AJ; Schmutzhard, E; Stover, JF; Thomé, C | 1 |
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| Enblad, P; Hillered, L; Howells, T; Lewén, A; Ronne-Engström, E; Rostami, E; Svedung Wettervik, T | 1 |
| Duke, M; Pandey, A; Rai, P; Srivastava, S | 1 |
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| Chen, P; Fang, R; Gupta, N; Liang, X; Shen, B; Xia, N; Yang, S; Ye, S; Yuan, J; Zhao, J; Zhou, Y | 1 |
| Beer, R; Gaasch, M; Helbok, R; Ianosi, B; Kofler, M; Miroz, JP; Morelli, P; Oddo, M; Pfausler, B; Rass, V; Schiefecker, AJ; Solari, D; Thomé, C | 1 |
| Chen, L; Cowan, AJ; Frezza, C; Gorman, JH; Gorman, RC; Hui, S; Hwang, HY; Imai, A; Jang, C; Kasprenski, L; Morscher, RJ; Okamoto, K; Rabinowitz, JD; Reyes, J; Saito, Y; Vaspoli, C; Wang, L; Zeng, X; Zsido, GA | 1 |
| Autry, A; Bok, R; Carvajal, L; Chang, S; Chen, HY; Chung, B; Crane, J; Gordon, J; Larson, PEZ; Li, Y; Mammoli, D; Shin, P; Slater, JB; Van Criekinge, M; Vigneron, DB; Xu, D | 1 |
| Alberini, CM; Descalzi, G; Gao, V; Steinman, MQ; Suzuki, A | 1 |
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| Britton, W; de Carvalho, LPS; Garza-Garcia, A; Greenwood, DJ; Gutierrez, MG; Horswell, S; Howell, S; Hunt, DM; Montague, CR; Monteleone, M; Phan, MD; Schembri, M; Serafini, A; Snijders, AP; Tan, L; VanderVen, B; West, NP | 1 |
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| Chen, AP; Eastham, JA; Fine, S; Gonen, M; Granlund, KL; Guo, YW; Hricak, H; Keshari, KR; Laudone, V; Lyashchenko, SK; Nicholson, D; Reuter, VE; Reznik, E; Robb, F; Sosa, RE; Tee, SS; Touijer, KA; Tropp, J; Vargas, HA | 1 |
| Huang, F; Li, J; Wang, T; Xia, J; Yao, W; Yu, X | 1 |
| Cheng, KY; Hong, PY; Kaksonen, A; Lehmann, R; Machuca, LL; Morris, C; Scarascia, G | 1 |
| Du, C; He, C; Wan, W; Wang, T; Wang, Y; Wu, S; Zou, R | 1 |
| Bettoni, J; Colin, E; Dakpé, S; Davrou, J; Devauchelle, B; Diouf, M; Testelin, S | 1 |
| Autry, AW; Bok, RA; Chang, S; Chaumeil, MM; Chen, HY; Chung, BT; Gordon, J; Kurhanewicz, J; Larson, PEZ; Le Page, LM; Li, Y; Mammoli, D; Ronen, SM; Shin, P; Slater, J; Sriram, R; Suszczynski, C; Tan, CT; Vigneron, DB | 1 |
| Alves, MG; de Lourdes Pereira, M; Jarak, I; Moreira, BP; Oliveira, PF; Silva, JF | 1 |
| Cheng, A; Ding, C; Duan, X; Gao, P; Guo, J; Jiang, Y; Pan, X; Pan, YY; Sang, Z; Shi, J; Wang, B; Wang, H; Wu, G; Wu, M; Wu, Q; Xu, T; Yang, D; Yang, Z; Zhang, H; Zhang, P; Zhang, Z; Zhou, CZ | 1 |
| Forsse, A; Hjelmborg, J; Mølstrøm, S; Nielsen, KS; Nielsen, TH; Nordström, CH; Nygaard, KH; Poulsen, FR; Yilmaz, S | 1 |
| Bruns, B; Eckert, GP; Esselun, C; Grewal, R; Hagl, S | 1 |
| Barros, LF; Esparza, A; González-Gutiérrez, A; Ibacache, A; Sierralta, J | 1 |
| Behrensen, C; Durrieu, L; Gándara, L; Wappner, P | 1 |
| Gallagher, MJ; Hogg, FRA; López, DM; Papadopoulos, MC; Saadoun, S; Sheen, HV; Zoumprouli, A | 1 |
| Bennett, GN; Kavraki, LE; Kim, SM; Moll, M; Peña, MI | 1 |
| Can, E; Comment, A; Couturier, DL; Doucey, MA; Kunz, N; Mishkovsky, M; Petrausch, U; Yoshihara, HAI | 1 |
| Goodman, RP; Ichinose, F; Marutani, E; Miyazaki, Y; Mootha, VK; Patgiri, A; Robert Bao, X; Schleifer, G; Shah, H; Sharma, R; Skinner, OS; To, TL; Zapol, WM | 1 |
| Hasunuma, T; Hidese, R; Kondo, A; Matsuda, M; Osanai, T | 1 |
| Jiang, R; Lin, H; Xu, S; Zhang, X | 1 |
| Fujita, T; Hamuro, J; Kinoshita, S; Mukai, A; Nakano, M; Numa, K; Sotozono, C; Toda, M; Tokuda, Y; Ueda, K; Ueno, M | 1 |
| Bok, R; Delos Santos, R; Gordon, J; Larson, PEZ; Overall, W; Qin, H; Reed, G; Santos, J; Tang, S; VanCriekinge, M; Vigneron, DB; Wang, ZJ | 1 |
| Dalwadi, MP; King, JR | 1 |
| Foolad, F; Javan, M; Khodagholi, F; Nabavi, SM | 1 |
| Buscemi, L; Hirt, L; Hyacinthe, JN; Lê, TP; Lepore, M; Mishkovsky, M | 1 |
| Picklo, MJ; Rust, BM; Yan, L | 1 |
| Wang, W; Yang, X | 1 |
| Hong, J; Lakshmanan, M; Lee, DY; Yeo, HC | 1 |
| Ackermann, PW; Capone, G; Edman, G; Juthberg, R; Svedman, S | 1 |
| Betts, DH; Cumming, RC; Kozlov, AM; Lone, A | 1 |
| Asara, JM; Becker, LM; Bizarro, L; Cain, MP; Kalluri, R; LeBleu, VS; Lorenzi, PL; Lovisa, S; McAndrews, KM; McGow, AK; O'Connell, JT; Raza, S; Sugimoto, H; Tampe, D; Vo, AP; Zeisberg, M; Zielinski, R | 1 |
| Ackerman, D; Gade, TPF; Johnson, O; Mercadante, M; Perkons, NR; Pilla, G; Profka, E | 1 |
| Beziere, N; Bouzin, C; Comment, A; Daniels, R; Fuchs, K; Kneilling, M; Neveu, MA; Pichler, BJ; Schmid, AM; Schwenck, J | 1 |
| Broeckling, CD; Dyer, MC; Ermisch, AF; Herrick, JR; Krisher, RL; Lyons, SM; Pasquariello, R; Rajput, SK; Schoolcraft, WB | 1 |
| Barkovich, AJ; Bok, R; Chen, Y; Ferriero, DM; Lee, BS; Mikrogeorgiou, A; Sheldon, RA; Xu, D | 1 |
| Lekomtseva, Y | 1 |
| Gureviciene, I; Jin, N; Tanila, H; Ziyatdinova, S | 1 |
| Cereda, M; Chatterjee, S; Duncan, I; Hamedani, H; Kadlecek, S; Pourfathi, M; Profka, H; Rizi, RR; Rosalino, M; Ruppert, K; Siddiqui, S; Xin, Y | 1 |
| Bao, YZ; Guo, YH; Li, XX; Luo, XG; Qi, W; Wang, N; Yu, CD; Zhang, TC | 1 |
| Dadi, PK; Denton, JS; Dickerson, MT; Graff, SM; Jacobson, DA; Kondapavuluru, RS; Nakhe, AY; Schaub, CM; Stanley, JE; Thorson, AS; Zaborska, KE | 1 |
| Bankson, JA; Gordon, JW; Larson, PEZ; Li, L; Michel, KA; Vigneron, DB; Walker, CM; Xu, Z | 1 |
| Hasenour, CM; Rahim, M; Young, JD | 1 |
| Deh, K; Eskandari, R; Granlund, KL; Keshari, KR; Kim, N; Mamakhanyan, A | 1 |
| Baleja, JD; Cronkright, AA; Huggins, GS; Stoffers, KM | 1 |
| Bhattacharya, P; Gammon, S; Liu, T; Piwnica-Worms, D; Rao, Y; Salzillo, T; Wang, J; Xi, Y; Zacharias, NM | 1 |
| Dumitrescu, S; Hosmann, A; Kozlov, AV; Milivojev, N; Reinprecht, A; Weidinger, A | 1 |
| Brautigam, CA; Deka, RK; Liu, WZ; Norgard, MV | 1 |
| Afzal, A; Ayers, C; Baxter, J; Chandra, A; Cole, S; de Lemos, J; Derner, K; Edpuganti, V; Froehlich, T; Haley, B; Hall, RG; Harrison, CE; Kallem, RR; Klemow, D; Lewis, C; Li, H; Liticker, J; MacNamara, J; Malloy, CR; Muthukumar, A; Park, JM; Pena, S; Putnam, WC; Raza, J; Reddy, S; Reed, GD; Subramaniyan, I; Syed, S; Unni, N; Yaros, K; Zaha, VG | 1 |
| Datta, K; Spielman, D | 1 |
| Horowitz, M; Kanaani, H; Mreisat, A; Saada, A | 1 |
| Debata, PR; Pani, S; Patra, A; Sahoo, A | 1 |
| Levitt, DG; Levitt, JE; Levitt, MD | 1 |
| Angus, DC; Bakalov, V; Chang, CH; Deshpande, R; Kaynar, AM; Le Moyec, L; Maloy, AL; Reyes-Uribe, L; Shapiro, SD; Wendell, SG | 1 |
| Caesa, P; Fakhri, D; Haas, NA; Kajimoto, M; Marwali, EM; Portman, MA; Rayhan, M; Roebiono, PS | 1 |
| Guo, S; Liu, J; Tao, Y; Wei, C; Yang, Q | 1 |
| Arai, M; Chihara, T; Harada, K; Hayasaka, Y; Ishida, K; Ishihara, T; Kitaguchi, T; Matsumoto, M; Mita, M; Takizawa, M; Tsuboi, T; Tsuno, S; Ueda, H | 1 |
| Ahamed, F; Eskandari, R; Granlund, KL; Jeong, S; Keshari, KR; Lees, H; Millan, M | 1 |
| Buyukuysal, RL; Gul, Z | 1 |
| Badolia, R; Berg, JA; Bott, AJ; Cluntun, AA; Cox, JE; Cunningham, CN; Diakos, NA; Drakos, SG; Ducker, GS; Fogarty, S; Holland, WL; Krokidi, AT; Lettlova, S; Luo, B; McKellar, SH; Merx, S; Navankasattusas, S; Olson, KA; Parnell, KM; Rutter, J; Shankar, TS; Skedros, S; Swiatek, WI; Taleb, I; Tatum, SM; Van Ry, T; Yu, X | 1 |
| Batsios, G; Costello, JF; Gillespie, AM; Larson, PEZ; Luchman, HA; Mukherjee, J; Phillips, JJ; Pieper, RO; Ronen, SM; Viswanath, P | 1 |
| Ahamed, F; Kurhanewicz, J; Larson, P; Sriram, R; Van Criekinge, M; Wang, ZJ | 1 |
| Barry, ST; Brindle, KM; Bunch, J; Couturier, DL; Dannhorn, A; Fala, M; Gibson, K; Goodwin, RJA; Hamm, G; Hesketh, R; Somai, V; Takats, Z; Wright, AJ | 1 |
| Abt, K; Castelo-Branco, R; Leão, PN | 1 |
| Bergers, G; Fendt, SM | 1 |
| de Leeuw, PW; Shenkin, A; Sobotka, L; Soeters, MR; Soeters, PB; Wolfe, RR | 1 |
| Aandahl, EM; Bergmann, GB; Berstad, AE; Brabrand, K; Dorenberg, E; Hagen, G; Haugaa, H; Horneland, R; Jenssen, TG; Kjøsen, G; Line, PD; Nordheim, E; Pischke, SE; Rydenfelt, K; Tønnessen, TI | 1 |
| Bloch, J; Comment, A; Cudalbu, C; Gruetter, R; Gusyatiner, O; Hamou, MF; Hegi, ME; Lanz, B; Mishkovsky, M; Vassallo, I | 1 |
| Chen, CC; Chen, LC; Chen, YJ; Hsieh, YL; Huang, KY; Lin, HA; Lin, HC; Lin, KH; Liu, TF; Wang, HH; Wei, YH | 1 |
| Antonelou, MH; Beirne, J; Buehler, PW; Busch, MP; Cendali, F; D'Alessandro, A; Dziewulska, KH; Fu, X; Gamboni, F; Hay, A; Kleinman, S; Kriebardis, A; Morrison, EJ; Nemkov, T; Spitalnik, SL; Thomas, T; Welsby, I; Zimring, JC | 1 |
| Bertolini, GL; Biazi, GR; de Souza Galia, WB; de Souza, HM; Frasson-Uemura, IG; Miksza, DR; Zaia, CTBV; Zaia, DAM | 1 |
| Brender, JR; Camphausen, KA; Kawai, T; Kishimoto, S; Kramp, T; Krishna, MC; Lee, JA; Tofilon, P | 1 |
| Davey, ME; Moradali, MF | 1 |
| Barber, DL; Kisor, K; Manoli, SS; Webb, BA | 1 |
| Bian, J; Cai, P; Feng, N; Feng, Z; Gu, J; Liu, X; Liu, Z; Yuan, Y; Zou, H | 1 |
| Hernández-Muñoz, R; Luna-Castro, M; Martiñón-Gutiérrez, G | 1 |
| Chen, J; Chhabra, A; Haller, RG; Harrison, CE; Jue, T; Liticker, J; Ma, J; Malloy, CR; Park, JM; Ratnakar, J; Reed, GD; Zun, Z | 1 |
| Autry, AW; Brender, JR; Chang, SM; Chen, HY; Gordon, JW; Kim, Y; Krishna, MC; Larson, PEZ; Li, Y; Vigneron, DB; Villanueva-Meyer, J; Xu, D | 1 |
| Bertelsen, LB; Hansen, ESS; Laustsen, C; Ruf, S; Sadowski, T | 1 |
| Aon, J; Eyster, T; Orzechowski, K; Patel, P; Ritz, D; Sévin, D; Vappiani, J | 1 |
| Forsse, A; Mamaev, D; Möller, S; Mölström, S; Nielsen, TH; Nordström, CH; Schmidt, H; Tencer, T; Toft, P; Venö, S | 1 |
| Aggarwal, R; Bok, RA; Chen, A; Chen, R; Delos Santos, R; Goddard, G; Gordon, JW; Kurhanewicz, J; Larson, PEZ; Qin, H; Reed, G; Riselli, AM; Ruscitto, DM; Slater, J; Sriram, R; Tang, S; van Criekinge, M; Vigneron, DB; Zhang, CT | 1 |
| Burne, RA; Lee, K; Taylor, ZA; Walker, AR; Zeng, L | 1 |
| Brown, LD; Jones, AK; Julian, CG; Limesand, SW; Lorca, RA; Moore, LG; Rozance, PJ; Wesolowski, SR | 1 |
| Blazey, T; Garbow, JR; Reed, GD; von Morze, C | 1 |
| Abramov, AY; Berezhnov, AV; Dolgacheva, LP; Fedotova, EI | 1 |
| Albustanji, S; Alhusban, AA; Hamadneh, LA; Shallan, AI | 1 |
| Arevalo, JA; Brooks, GA; Curl, CC; Duong, JJ; Horning, MA; Leija, RG; Osmond, AD | 1 |
| Bøgh, N; Hansen, E; Jørgensen, SH; Laustsen, C; Væggemose, M; Wiggers, H | 1 |
| Bergmann, GB; Bjørnbeth, BA; Grindheim, G; Haugaa, H; Kjøsen, G; Labori, KJ; Lindholm, E; Line, PD; Pischke, SE; Tønnessen, TI; Yaqub, S | 1 |
| Carpenter, KLH; Czosnyka, M; Donnelly, J; Guilfoyle, MR; Helmy, A; Hutchinson, PJ; Menon, DK; Pickard, JD; Smielewski, P; Stovell, MG; Timofeev, I | 1 |
| Hiraki, N; Tanaka, TD; Yoshimura, M | 1 |
| Abiko, Y; Kobayashi, Y; Liu, S; Otani, H; Sasaki, S; Sato, S; Shinohara, Y; Takahashi, N; Wang, X; Washio, J | 1 |
| Belovich, JM; Chalhoub, ER | 1 |
| Bainbridge, A; Bullock, M; Caselton, L; Chowdhury, R; Gadian, DG; Golay, X; Gong, F; Mathew, M; Müller, CA; Oliver-Taylor, A; Papoutsaki, MV; Punwani, S; Retter, A; Rogers, H; Ryu, J; Singh, S; Smith, L; Syer, T | 1 |
| Bellozi, PMQ; Itinose, AM; Koerich, S; Marek, CB; Sandrini, F; Schneider, SCS; Silva, FC | 1 |
| Binda, C; Brigotti, M; Cerini, S; Dal Piaz, F; Di Stefano, G; Hochkoeppler, A; Iacovino, LG; Pasti, AP; Rossi, M; Rossi, V; Tomaselli, F | 1 |
| Bøtker, HE; Hansen, ESS; Hansen, K; Jespersen, NRV; Laustsen, C; Pedersen, M; Wang, T | 1 |
| Bertelsen, LB; Blicher, JU; Bøgh, N; Grist, JT; Hansen, ESS; Laustsen, C; Rasmussen, CW; Tyler, DJ | 1 |
| Annoni, F; Bogossian, EG; Creteur, J; Fratino, S; Giannì, G; Minini, A; Oddo, M; Peluso, L; Schuind, S; Taccone, FS | 1 |
| Bommer, GT; Corbet, C; Drappier, M; Feron, O; Herinckx, G; Hue, L; Jacobs, R; Johanns, M; Messens, J; Rider, MH; Steinberg, GR; Tajeddine, N; Vertommen, D; Young, D | 1 |
| Barger, C; Batsios, G; Costello, JF; Gillespie, AM; Ronen, SM; Stevers, N; Taglang, C; Tran, M; Viswanath, P | 1 |
| Akin, N; Anckaert, E; Billooye, K; Cava-Cami, B; Coucke, W; Herta, AC; Klamt, F; Saucedo-Cuevas, L; Smitz, J; van Leersum, J; von Mengden, L | 1 |
| Bertelsen, LB; Blicher, JU; Bøgh, N; Hansen, ESS; Laustsen, C; Tankisi, H | 1 |
| Autry, AW; Bok, RA; Frost, MM; Gordon, JW; Hu, JY; Kim, Y; Larson, PEZ; Li, Y; Vigneron, DB; Villanueva-Meyer, JE; Xu, D | 1 |
| Elia, I; Freeman, GJ; Haigis, MC; Johnson, S; Joshi, S; Kurmi, K; Notarangelo, G; Rowe, JH; Sharpe, AH; Weiss, S | 1 |
| Allinson, K; Basu, B; Brindle, KM; Carmo, BD; Chhabra, A; Daniels, CJ; Deen, S; Frary, A; Gallagher, FA; Gill, AB; Gillard, JH; Graves, MJ; Grist, JT; Hilborne, S; Jefferies, S; Kaggie, J; Laurent, MC; Locke, M; Mair, R; Matys, T; McLean, MA; Patterson, I; Price, SJ; Riemer, F; Santarius, T; Schulte, RF; Slough, R; Ursprung, S; Wason, J; Watts, C; Wilkinson, I; Woitek, R; Zaccagna, F | 1 |
| Gnocchi, D; Kurzyk, A; Lentini, G; Mazzocca, A; Mintrone, A; Sabbà, C | 1 |
| Li, G; Ma, Y; Ren, G; Wang, X; Zheng, Z | 1 |
| Autry, AW; Bush, NAO; Chang, SM; Chen, HY; Clarke, JL; Gordon, JW; Hu, JY; Kim, Y; Lafontaine, M; Larson, PEZ; Li, Y; Lupo, JM; Vaziri, S; Vigneron, DB; Villanueva-Meyer, JE; Xu, D | 1 |
| Abellar, KA; Cope, JD; Nguyen, TB; Tran, LN | 1 |
| Bello, JE; Cardé, RT | 1 |
| Chen, X; Feng, Y; Lu, W; Xi, Y; Xie, X; Xu, S; Zhang, S; Zhang, X; Zhou, C | 1 |
| Aebisher, D; Bartusik-Aebisher, D; Kawczyk-Krupka, A; Truszkiewicz, A; Zalejska-Fiolka, J | 1 |
| Chen, C; Ding, L; Guo, J; Liu, H; Ma, Y; Qiao, X; Wang, J; Wang, M; Yang, T; Zhao, S | 1 |
| Funk, AM; Hever, T; Khemtong, C; Malloy, CR; Maptue, N; Rahim, M; Sharma, G; Trigo Mijes, ML; Wen, X; Young, JD | 1 |
| Arenas, J; Blanco-Echevarría, A; Blázquez, A; Domínguez-González, C; Esteban, J; Garrido-Moraga, R; Hidalgo Mayoral, I; Lucia, A; Martín, MA; Palma-Milla, C; Rabasa, M; Rubio, JC; Serrano-Lorenzo, P | 1 |
| Jin, YS; Lane, S; Turner, TL | 1 |
| Fang, Y; Huang, C; Liang, Y; Liu, H; Liu, M; Yu, W; Zhao, G; Zhou, H | 1 |
| Baurain, JF; Bouzin, C; Farah, C; Gallez, B; Jordan, BF; Knezevic, Z; Leucci, E; Mignion, L; Neveu, MA | 1 |
| de Gusmao, CM; Peixoto de Barcelos, I; Pinto, ALR; Silveira-Moriyama, L | 1 |
| Morava, E; Oglesbee, D | 1 |
| Al Kattan, M; Mohammad, R | 1 |
| Dong, J; Guo, L; Hong, NN; Lusk, JA; Nagana Gowda, GA; Pascua, V; Raftery, D; Sweet, IR | 1 |
| Betenbaugh, MJ; Cole, RN; DeVine, L; Dhara, VG; Kumar, S; Lau, EC; More, AJ; Naik, HM | 1 |
| Alfonta, L; Boyarski, A; Eichler, J; Paz, S; Shlush, N | 1 |
| Braren, R; Grashei, M; Heid, I; Hundshammer, C; Nagel, L; Schilling, F; Skinner, JG; Topping, GJ; van Heijster, FHA | 1 |
| Bankson, JA; Fuentes, DT; Harlan, CJ; Patel, RJS | 1 |
| Agarwal, S; Gordon, JW; Ji, X; Kurhanewicz, J; Larson, PEZ; Mali, I; Mattingly, M; Sahin, SI; Sinha, A; Sriram, R; Subramaniam, S | 1 |
| Ho, WM; Petr, O; Schmidt, FA; Thomé, C | 1 |
| AbuSalim, J; Jankowski, CSR; Lee, WD; Liang, L; Neinast, MD; Rabinowitz, JD; Samarah, LZ | 1 |
| Black, SE; Bragagnolo, ND; Cappelletto, NIC; Chen, AP; Cunningham, CH; Endre, R; Geraghty, B; Heyn, C; Lee, CY; Ma, N; MacIntosh, BJ; Perks, WJ; Soliman, H; Stanisz, GJ; Uthayakumar, B | 1 |
| Holeček, M | 1 |
| Chen, M; Fan, L; Tan, WS; Wang, C; Wang, J; Ye, Q; Zhao, L | 1 |
| Haraguchi, Y; Hasunuma, T; Inabe, K; Kato, Y; Kondo, A; Shimizu, T | 1 |
| Jiang, C; Li, Y; Liao, N; Liu, G; Shang, X; Shao, D; Shi, J; Xu, F; Yin, D | 1 |
| Chen, Y; Christensen, G; Paquet-Durand, F; Schipper, N; Trautwein, C; Urimi, D; Zizmare, L | 1 |
| Broskey, NT; Dohm, GL; Houmard, JA; Jevtovic, F; Jones, TE; Kern, K; Lopez, CA; May, LE; Pories, WJ; Tanner, CJ; Zheng, D | 1 |
| Aboudhiaf, S; Balança, B; Barcelos, GK; Carrillon, R; Dailler, F; Grousson, S; Lieutaud, T; Marinesco, S; Perret-Liaudet, A; Tholance, Y | 1 |
| Autry, AW; Bok, RA; Chang, SM; Chen, HY; Chung, BT; Gordon, JW; Hu, JY; Kim, Y; Larson, PEZ; Lee, PM; Li, Y; Suszczynski, C; Tan, CT; Vigneron, DB; Villanueva-Meyer, JE; Xu, D | 1 |
| Arponen, O; Gallagher, FA; Wodtke, P; Woitek, R | 1 |
| Andersen, JR; Andreassen, T; Beisland, C; Hopland-Nechita, FV; Rajalahti, TK | 1 |
| Domschke, K; Endres, D; Maier, S; Menke, M; Nickel, K; Runge, K; Schumann, A; Tebartz van Elst, L; Tucci, S | 1 |
| Choi, YS; Kim, CH; Kim, E; Lee, JE; Song, HT; Song, JE | 1 |
| Funaba, M; Matsui, T; Takagi, F; Tomonaga, S | 1 |
| Calmettes, G; John, S; Ribalet, B; Xu, S | 1 |
| Afshar, M; van Hall, G | 1 |
| Kurawaka, M; Sasaki, N; Shimura, F; Yamazaki, Y | 1 |
| Esparza, A; Gaete, J; González-Gutiérrez, A; Köhler-Solis, A; Sierralta, J; Toledo, J | 1 |
| Agemy, L; Brenner, O; Frydman, L; Montrazi, ET; Peters, DC; Sasson, K; Scherz, A | 1 |
94 review(s) available for lactic acid and pyruvic acid
| Article | Year |
|---|---|
Ruminant hepatic metabolism of volatile fatty acids, lactate and pyruvate.
Topics: Animals; Fatty Acids, Volatile; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Ruminants | 1992 |
MELAS syndrome. Report of two patients, and comparison with data of 24 patients derived from the literature.
Topics: Biopsy; Child; Child, Preschool; Electroencephalography; Electromyography; Energy Metabolism; Enzymes; Epilepsies, Myoclonic; Female; Humans; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Muscles; Neuromuscular Diseases; Pyruvates; Pyruvic Acid; Syndrome | 1991 |
Mechanisms and regulation of lactate, pyruvate and ketone body transport across the plasma membrane of mammalian cells and their metabolic consequences.
Topics: Animals; Biological Transport, Active; Cell Membrane; Erythrocyte Membrane; Humans; Ketone Bodies; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Tissue Distribution | 1990 |
Pathophysiology of cerebrospinal fluid in head injury: Part 1. Pathological changes in cerebrospinal fluid solute composition after traumatic injury.
Topics: Acetylcholine; Brain Edema; Brain Injuries; Calcium; Cerebrospinal Fluid Proteins; Dopamine; Fatty Acids, Unsaturated; Histamine; Humans; Kallikreins; Kinins; Lactates; Lactic Acid; Myelin Basic Protein; Neurotransmitter Agents; Norepinephrine; Potassium; Prostaglandins; Pyruvates; Pyruvic Acid; Serotonin | 1986 |
Cellular and molecular events underlying epileptic brain damage.
Topics: Acidosis; Animals; Brain; Brain Damage, Chronic; Calcium; Cell Survival; Cerebral Infarction; Electroconvulsive Therapy; Electroshock; Epilepsy; Fatty Acids, Nonesterified; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Nucleotides; Oxygen Consumption; Phospholipids; Potassium; Proteins; Pyruvates; Pyruvic Acid | 1986 |
Disorders of the pyruvate dehydrogenase complex.
Topics: Acetyl Coenzyme A; Acetyltransferases; Acidosis; Brain; Carbon Dioxide; Child; Child, Preschool; Coenzyme A; Cranial Nerves; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Facial Bones; Feedback; Humans; Lactates; Lactic Acid; Leigh Disease; Molecular Weight; Movement Disorders; NAD; Nervous System Diseases; Phosphoric Monoester Hydrolases; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Spectrophotometry | 1986 |
Myoclonus and mitochondrial myopathy.
Topics: Adolescent; Brain Diseases, Metabolic; Central Nervous System Diseases; Electroencephalography; Epilepsies, Myoclonic; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Evoked Potentials, Visual; Humans; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Myoclonus; Oxidative Phosphorylation; Pedigree; Pyruvates; Pyruvic Acid | 1986 |
Mitochondrial abnormalities in choroid plexus of Leigh disease.
Topics: Brain Diseases, Metabolic; Child; Child, Preschool; Choroid Plexus; Female; Humans; Infant; Lactates; Lactic Acid; Leigh Disease; Male; Microscopy, Electron; Mitochondria; Pyruvates; Pyruvic Acid | 1988 |
An appreciation of the coronary circulation.
Topics: Blood Pressure; Collateral Circulation; Coronary Circulation; Coronary Disease; Coronary Vessels; Diastole; Humans; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Sympathetic Nervous System; Systole; Vascular Resistance; Vasoconstriction; Vasodilation | 1986 |
Glucose metabolism in renal tubular function.
Topics: Animals; Biological Transport, Active; Carbohydrate Metabolism; Gluconeogenesis; Glucose; Glycolysis; Homeostasis; Hormones; Kidney Tubules; Kinetics; Lactates; Lactic Acid; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvates; Pyruvic Acid; Sodium | 1986 |
On-line determination of biochemical/physiological parameters in the fermentation of animal cells in a continuous or discontinuous mode.
Topics: Amino Acids; Ammonia; Animals; Biomedical Engineering; Cells; Cells, Cultured; Fermentation; Glucose; Lactates; Lactic Acid; Online Systems; Pyruvates; Pyruvic Acid | 1986 |
The anaerobic threshold: definition, physiological significance and identification.
Topics: Acidosis; Adult; Anaerobiosis; Glycolysis; Heart Diseases; Humans; Kinetics; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Models, Cardiovascular; Myocardium; Oxygen Consumption; Physical Endurance; Physical Exertion; Pyruvates; Pyruvic Acid | 1986 |
Anaerobic threshold: review of the concept and directions for future research.
Topics: Acidosis; Anaerobiosis; Animals; Glycolysis; Humans; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Muscle Contraction; Muscles; Oxidation-Reduction; Oxygen Consumption; Physical Endurance; Physical Exertion; Pyruvates; Pyruvic Acid; Ventilation-Perfusion Ratio | 1985 |
Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport.
Topics: Amino Acids; Animals; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Citric Acid Cycle; Culture Techniques; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Glycogen; Humans; Ketones; Kidney; Kidney Tubules, Proximal; Lactates; Lactic Acid; Lipid Metabolism; Oxidation-Reduction; Perfusion; Pyruvates; Pyruvic Acid | 1985 |
An evaluation of biochemical aspects of intravenous fructose, sorbitol and xylitol administration in man.
Topics: Acid-Base Equilibrium; Adenosine Triphosphate; Biological Transport; Blood Glucose; Energy Metabolism; Fructose; Glucose; Glycogen; Humans; Infusions, Parenteral; Insulin; Insulin Secretion; Lactates; Lactic Acid; NAD; Phosphorylation; Pyruvates; Pyruvic Acid; Sorbitol; Triglycerides; Xylitol | 1985 |
Tissue redox-state potential (E'0)--as regulator of physiological processes.
Topics: Aging; Animals; Biological Transport, Active; Blood Physiological Phenomena; Cell Membrane; Cell Physiological Phenomena; Central Nervous System; Citric Acid Cycle; Cyclic AMP; Cyclic GMP; Digestive System Physiological Phenomena; DNA; Glutathione; Heart; Lactates; Lactic Acid; Muscle Contraction; Muscle, Smooth; Muscles; Oxidation-Reduction; Peripheral Nerves; Physiology; Potentiometry; Pyruvates; Pyruvic Acid; Receptors, Cell Surface; Sulfhydryl Compounds | 1983 |
Lactic acidosis in the brain: occurrence, triggering mechanisms and pathophysiological importance.
Topics: Acidosis; Animals; Blood Glucose; Brain; Brain Ischemia; Carbon Dioxide; Glucose; Hypoxia, Brain; Intracellular Fluid; Lactates; Lactic Acid; Phosphofructokinase-1; Pyruvates; Pyruvic Acid; Seizures | 1982 |
Physiological basis for human in vitro fertilization.
Topics: Acrosin; Acrosome; Animals; Body Fluids; Culture Media; Ejaculation; Electrolytes; Embryo Transfer; Epididymis; Fallopian Tubes; Female; Fertilization in Vitro; Humans; Lactates; Lactic Acid; Laparoscopy; Male; Menstruation; Oocytes; Ovarian Follicle; Protease Inhibitors; Pyruvates; Pyruvic Acid; Spermatozoa | 1982 |
Regulation of metabolite overproduction in Klebsiella aerogenes.
Topics: Adenosine Triphosphate; Aerobiosis; Ammonia; Anaerobiosis; Carbon-Oxygen Lyases; Fermentation; Glucose; Klebsiella pneumoniae; Lactates; Lactic Acid; Lactoylglutathione Lyase; Lyases; Oxygen Consumption; Phosphorylation; Pyruvates; Pyruvic Acid; Thiolester Hydrolases | 1983 |
The conversion of glucose to liver glycogen: a new pathway?
Topics: Animals; Fasting; Fatty Acids; Food; Gluconeogenesis; Glucose; Insulin; Lactates; Lactic Acid; Liver; Liver Glycogen; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1984 |
Substrate utilization and brain development.
Topics: 3-Hydroxybutyric Acid; Adolescent; Animals; Blood-Brain Barrier; Brain; Carrier Proteins; Cerebrovascular Circulation; Child; Child, Preschool; Glucose; Humans; Hydroxybutyrates; Infant; Infant, Newborn; Ketone Bodies; Lactates; Lactic Acid; Mathematics; Monosaccharide Transport Proteins; Papio; Pyruvates; Pyruvic Acid; Sheep; Species Specificity | 1982 |
Disturbances of metabolic homeostasis is liver disease.
Topics: Fasting; Glucagon; Gluconeogenesis; Glucose Tolerance Test; Growth Hormone; Homeostasis; Humans; Hydrocortisone; Insulin; Lactates; Lactic Acid; Lipids; Liver Cirrhosis; Liver Diseases; Pyruvates; Pyruvic Acid | 1981 |
[Anaerobic threshold: definition, physiology and methods of determination].
Topics: Anaerobic Threshold; Blood Gas Analysis; Exercise Test; Heart Diseases; Humans; Lactates; Lactic Acid; Physical Exertion; Pyruvates; Pyruvic Acid | 1993 |
Patterns of the metabolic and endocrine stress response to surgery and medical illness in infancy and childhood.
Topics: Adult; Age Factors; Blood Glucose; Child; Child, Preschool; Humans; Hydrocortisone; Infant; Infant, Newborn; Infant, Premature; Insulin; Insulin Secretion; Lactates; Lactic Acid; Leukocyte Count; Lymphocytes; Postoperative Complications; Pyruvates; Pyruvic Acid; Severity of Illness Index; Stress, Physiological | 1993 |
Splanchnic lactate production in cardiac surgery patients.
Topics: Coronary Artery Bypass; Glucose; Humans; Lactates; Lactic Acid; Oxygen Consumption; Pyruvates; Pyruvic Acid; Splanchnic Circulation | 1993 |
Effect of different buffers on the biocompatibility of CAPD solutions.
Topics: Acid-Base Equilibrium; Bicarbonates; Buffers; Cell Division; Cell Survival; Dialysis Solutions; Histidine; Humans; Hydrogen-Ion Concentration; Kidney Failure, Chronic; Lactates; Lactic Acid; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Pyruvates; Pyruvic Acid | 1996 |
[Red cell glycolytic intermediates].
Topics: 2,3-Diphosphoglycerate; Blood Glucose; Dihydroxyacetone Phosphate; Diphosphoglyceric Acids; Fructosediphosphates; Fructosephosphates; Glucose-6-Phosphate; Glucosephosphates; Glyceraldehyde 3-Phosphate; Glyceric Acids; Humans; Lactates; Lactic Acid; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid | 1995 |
Metabolic engineering of sugar catabolism in lactic acid bacteria.
Topics: Biological Transport; Carbohydrate Metabolism; Fermentation; Genetic Engineering; Lactic Acid; Lactobacillus; Oxidation-Reduction; Oxidoreductases; Phosphoenolpyruvate Sugar Phosphotransferase System; Polysaccharides, Bacterial; Pyruvic Acid; Streptococcaceae | 1996 |
Physiology of pyruvate metabolism in Lactococcus lactis.
Topics: Adenosine Triphosphate; Amino Acids; Carbohydrate Metabolism; Fermentation; Lactic Acid; Lactococcus lactis; Pyruvic Acid | 1996 |
Metabolic fuel utilization and pyruvate oxidation during the postnatal period.
Topics: Animals; Brain; Energy Metabolism; Humans; Infant, Newborn; Lactic Acid; Oxidation-Reduction; Pyruvic Acid | 1996 |
Fatty acid oxidation in the heart.
Topics: Adenosine Triphosphate; Animals; Calcium; Fatty Acids; Fish Oils; Humans; Lactic Acid; Mitochondria, Heart; Myocardial Contraction; Myocardium; Oxidation-Reduction; Oxygen Consumption; Palmitoylcarnitine; Pyruvic Acid; Rats; Reperfusion Injury | 1996 |
Buffers: bicarbonate, lactate and pyruvate.
Topics: Acidosis, Lactic; Bicarbonates; Buffers; Dialysis Solutions; Humans; Lactic Acid; Peritoneal Dialysis; Pyruvic Acid | 1996 |
[Pyruvate decarboxylase deficiency].
Topics: Biomarkers; Diagnosis, Differential; Female; Humans; Lactic Acid; Male; Metabolism, Inborn Errors; Mutation; Prognosis; Pyruvate Decarboxylase; Pyruvic Acid | 1998 |
Glucose and lactate metabolism by Actinomyces naeslundii.
Topics: Actinomyces; Aerobiosis; Anaerobiosis; Bicarbonates; Dental Plaque; Ecology; Glucose; Glycogen; Glycolysis; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Lyases; Mouth; Oxidation-Reduction; Phosphoenolpyruvate; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 1999 |
Embryo nutrition and energy metabolism and its relationship to embryo growth, differentiation, and viability.
Topics: Amino Acids; Animals; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Embryonic Development; Energy Metabolism; Female; Glucose; Hexokinase; Humans; Lactic Acid; Nutritional Physiological Phenomena; Phosphofructokinase-1; Pregnancy; Pyruvic Acid | 2000 |
[Alpha ketoglutarate dehydrogenase deficiency].
Topics: Acetoacetates; Citric Acid Cycle; Diagnosis, Differential; Energy Metabolism; Female; Humans; Infant; Infant, Newborn; Ketoglutarate Dehydrogenase Complex; Lactic Acid; Male; Mitochondria; Prognosis; Pyruvates; Pyruvic Acid | 2001 |
[Pure mitochondrial myopathy].
Topics: Child; Cytochrome-c Oxidase Deficiency; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Humans; Lactic Acid; Male; Mitochondrial Myopathies; Multienzyme Complexes; Muscles; NADH, NADPH Oxidoreductases; Oxidoreductases; Pyruvic Acid; Succinate Dehydrogenase | 2001 |
Advantages of pyruvate over lactate in peritoneal dialysis solutions.
Topics: Apoptosis; Dialysis Solutions; Free Radical Scavengers; Humans; Hydrogen-Ion Concentration; Lactic Acid; NF-kappa B; Protein Kinase C; Pyruvic Acid | 2001 |
Oxidative and nonoxidative metabolism of excited neurons and astrocytes.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Cerebrovascular Circulation; Energy Metabolism; Glucose; Glutamic Acid; Glycolysis; Humans; Lactic Acid; Neurons; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Rats; Synaptic Transmission | 2002 |
[The screening test for mitochondrial disease].
Topics: Biomarkers; Diagnosis, Differential; Glucose Tolerance Test; Humans; Lactic Acid; Mass Screening; Mitochondrial Diseases; Pyruvic Acid | 2002 |
Lactate, glucose and energy metabolism in the ischemic brain (Review).
Topics: Acidosis, Lactic; Anaerobiosis; Animals; Brain; Brain Damage, Chronic; Brain Ischemia; Corticosterone; Energy Metabolism; Glucose; Glycolysis; Humans; Hyperglycemia; Hypoxia-Ischemia, Brain; Lactic Acid; Models, Biological; Pyruvic Acid; Rats | 2002 |
[Lactate . pyruvate].
Topics: Acidosis, Lactic; Biomarkers; Diabetes Mellitus; Humans; Lactic Acid; Neoplasms; Pyruvic Acid | 2002 |
Anaerobic sugar catabolism in Lactococcus lactis: genetic regulation and enzyme control over pathway flux.
Topics: Anaerobiosis; Carbohydrate Metabolism; Fermentation; Galactose; Glycolysis; Lactic Acid; Lactococcus lactis; Pyruvic Acid | 2002 |
Practical implications of lactate and pyruvate metabolism by lactic acid bacteria in food and beverage fermentations.
Topics: Beverages; Fermentation; Food Microbiology; Lactic Acid; Lactobacillus; Meat Products; Pyruvic Acid | 2003 |
Engineering metabolic highways in Lactococci and other lactic acid bacteria.
Topics: Energy Metabolism; Ethanol; Food Technology; Gene Expression Regulation, Bacterial; Genetic Engineering; Hexoses; Lactic Acid; Lactococcus; Lactose; Pyruvic Acid | 2004 |
[Progress in diagnosis of and therapy for diabetic lactic acidosis].
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Blood Gas Analysis; Consciousness Disorders; Diabetes Complications; Diagnosis, Differential; Glucose; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Metformin; Pyruvic Acid; Sodium Bicarbonate | 2004 |
Variations in the energy metabolism of biotechnologically relevant heterofermentative lactic acid bacteria during growth on sugars and organic acids.
Topics: Aldehyde-Lyases; Arginine; Biotechnology; Citric Acid; Energy Metabolism; Fermentation; Gram-Positive Bacteria; Hexoses; Lactic Acid; Malates; Pyruvic Acid | 2006 |
Metabolic and genetic regulation of cardiac energy substrate preference.
Topics: Acyl Coenzyme A; Amino Acids; Animals; Carbohydrate Metabolism; Carnitine; Citric Acid Cycle; Energy Metabolism; Ethanol; Fatty Acids; Gene Expression Regulation, Developmental; Glucose; Glycogen; Glycogenolysis; Glycolysis; Heat-Shock Proteins; Hexokinase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemic Preconditioning, Myocardial; Ketone Bodies; Lactic Acid; Myocardium; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Peroxisome Proliferator-Activated Receptors; Pyruvic Acid; Receptors, Estrogen; Transcription Factors | 2007 |
Lactate and malignant tumors: a therapeutic target at the end stage of glycolysis.
Topics: Animals; Antineoplastic Agents; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Metabolic Networks and Pathways; Monocarboxylic Acid Transporters; Pyruvic Acid | 2007 |
HIF-1 mediates the Warburg effect in clear cell renal carcinoma.
Topics: Animals; Carcinoma, Renal Cell; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Neoplasms; Lactic Acid; Mitochondria; Oxidative Phosphorylation; Oxygen; Proteasome Endopeptidase Complex; Protein Binding; Pyruvic Acid; Von Hippel-Lindau Tumor Suppressor Protein | 2007 |
Compartmentalization of brain energy metabolism between glia and neurons: insights from mathematical modeling.
Topics: Animals; Biotransformation; Brain Chemistry; Energy Metabolism; Glucose; Humans; Kinetics; Lactic Acid; Models, Statistical; Neuroglia; Neurons; Pyruvic Acid | 2007 |
Human fetal brain chemistry as detected by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Fetus; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Protons; Pyruvic Acid | 2009 |
What learning in day-old chickens can teach a neurochemist: focus on astrocyte metabolism.
Topics: Animals; Animals, Newborn; Astrocytes; Biological Transport, Active; Brain Chemistry; Chickens; Energy Metabolism; Gap Junctions; Glucose; Glutamates; Glycogen; Glycolysis; Humans; Lactic Acid; Learning; Neurotransmitter Agents; Pyruvic Acid | 2009 |
Mitochondrial matters of the heart: a plethora of regulatory modes to maintain function for a long lifetime.
Topics: Adenosine Triphosphate; Animals; Glucose; Glycolysis; Hexokinase; Humans; Lactic Acid; Longevity; Mitochondria, Heart; Mitochondrial Membranes; Oxidative Phosphorylation; Pyruvic Acid | 2009 |
Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.
Topics: Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Energy Metabolism; Glycolysis; Humans; Lactic Acid; NAD; NADP; Neoplasms; Oxidation-Reduction; Pyruvic Acid; Radiation Tolerance; Sensitivity and Specificity | 2009 |
Tumor cell energy metabolism and its common features with yeast metabolism.
Topics: Animals; Apoptosis; Citric Acid Cycle; Energy Metabolism; Fermentation; Glucose; Glycolysis; Humans; Lactic Acid; Neoplasms; Pyruvic Acid; Saccharomyces cerevisiae | 2009 |
Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells.
Topics: Adaptation, Biological; Cell Hypoxia; Cell Proliferation; Energy Metabolism; Gene Expression Regulation; Genes, myc; Glucose; Glutamine; Humans; Lactic Acid; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phosphatidylinositol 3-Kinase; Protein Serine-Threonine Kinases; Pyruvic Acid | 2011 |
Excitatory action of GABA on immature neurons is not due to absence of ketone bodies metabolites or other energy substrates.
Topics: Animals; Animals, Newborn; Brain; Energy Metabolism; gamma-Aminobutyric Acid; In Vitro Techniques; K Cl- Cotransporters; Ketone Bodies; Lactic Acid; Neurons; Pyruvic Acid; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters | 2011 |
Glycolysis and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoantigens; Cell Differentiation; Cell Proliferation; Fructose-Bisphosphate Aldolase; Glucose-6-Phosphate Isomerase; Glycolysis; Humans; Lactic Acid; Neovascularization, Pathologic; Phosphopyruvate Hydratase; Pyruvic Acid; Synovial Membrane | 2011 |
Hypoxia-inducible factors and their roles in energy metabolism.
Topics: Animals; Carbohydrate Metabolism; Energy Metabolism; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Lactic Acid; Lipid Metabolism; Oxygen Consumption; Pyruvic Acid | 2012 |
[Tumor pathophysiology].
Topics: Animals; Blood Glucose; Cell Hypoxia; Energy Metabolism; Humans; Lactic Acid; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplasms; Phenotype; Pyruvic Acid; Transplantation, Heterologous | 2012 |
Changes in cerebral oxidative metabolism in patients with acute liver failure.
Topics: Amino Acids; Ammonia; Animals; Brain; Brain Chemistry; Humans; Hyperammonemia; Lactic Acid; Liver Failure, Acute; Oxidation-Reduction; Pyruvic Acid | 2013 |
Engineering strategies aimed at control of acidification rate of lactic acid bacteria.
Topics: Adenosine Triphosphate; Bioreactors; Biotechnology; Fermentation; Glucose; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillus; Pyruvic Acid | 2013 |
Flat spin and negative Gz in high-altitude free fall: pathophysiology, prevention, and treatment.
Topics: Altitude; Arrhythmias, Cardiac; Blood Glucose; Brain Edema; Cerebrovascular Circulation; Confusion; Coronary Circulation; Emergency Medical Services; Emergency Treatment; Eye Hemorrhage; Hemorrhage; Humans; Hypogravity; Hypotension; Hypoxia, Brain; Intraocular Pressure; Lactic Acid; Lung Diseases; Oxygen; Proprioception; Pulmonary Circulation; Pulmonary Edema; Purpura; Pyruvic Acid; Regional Blood Flow; Respiratory Rate; Syncope | 2013 |
[Progress in biotransformation of bio-based lactic acid ].
Topics: Acrylates; Bacteria; Biotechnology; Biotransformation; Fermentation; Industrial Microbiology; Lactic Acid; Propylene Glycol; Pyruvic Acid; Yeasts | 2013 |
The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanism.
Topics: Anoikis; Cell Proliferation; Citric Acid Cycle; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kisspeptins; Lactic Acid; Mitochondria; Neoplasm Metastasis; Neoplasms; Oxidative Phosphorylation; Oxidative Stress; Pyruvic Acid; Reactive Oxygen Species; Snail Family Transcription Factors; Transcription Factors; Tumor Suppressor Protein p53 | 2015 |
Comprehensive review on lactate metabolism in human health.
Topics: Alanine; Carbon Dioxide; Diabetes Mellitus; Glucose; Humans; Lactic Acid; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Oxidation-Reduction; Oxidoreductases; Oxygen; Pyruvic Acid | 2014 |
Brain tissue oxygenation, lactate-pyruvate ratio, and cerebrovascular pressure reactivity monitoring in severe traumatic brain injury: systematic review and viewpoint.
Topics: Arterial Pressure; Brain Injuries; Cerebrovascular Circulation; Humans; Lactic Acid; Monitoring, Physiologic; Oxygen Consumption; Pyruvic Acid | 2014 |
Lactate shuttling and lactate use as fuel after traumatic brain injury: metabolic considerations.
Topics: Animals; Brain Injuries; Brain Ischemia; Glutamic Acid; Humans; Lactic Acid; Mitochondria; Oxidation-Reduction; Pyruvic Acid | 2014 |
[Quantitative cellular metabolism can be estimated by hyperpolarized magnetic resonance].
Topics: Administration, Intravenous; Biosensing Techniques; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Prostatic Neoplasms; Pyruvic Acid | 2014 |
Aspects of energetic substrate metabolism of in vitro and in vivo bovine embryos.
Topics: Animals; Blastocyst; Carbon Dioxide; Cattle; Embryo Culture Techniques; Energy Metabolism; Female; Fertilization in Vitro; Glucose; Lactic Acid; Oocytes; Oxygen Consumption; Pregnancy; Pyruvic Acid | 2015 |
Introduction to the molecular basis of cancer metabolism and the Warburg effect.
Topics: Apoptosis; Genes, Neoplasm; Glycolysis; Humans; Lactic Acid; Mitochondria; Neoplasms; Pyruvic Acid; Reactive Oxygen Species | 2015 |
Molecular action of metformin in hepatocytes: an updated insight.
Topics: AMP-Activated Protein Kinases; Dihydroxyacetone Phosphate; Electron Transport Complex I; Gluconeogenesis; Glycerolphosphate Dehydrogenase; Hepatocytes; Humans; Hypoglycemic Agents; Lactic Acid; Metformin; Mitochondria, Liver; Pyruvic Acid | 2015 |
[Investigation of Predisposition Biomarkers to Identify Risk Factors for Drug-induced Liver Injury in Humans: Analyses of Endogenous Metabolites in an Animal Model Mimicking Human Responders to APAP-induced Hepatotoxicity].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Biomarkers; Blood Glucose; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Food Deprivation; Humans; Lactic Acid; Nutritional Status; Pyruvic Acid; Risk Factors | 2015 |
Cancer metabolism: a therapeutic perspective.
Topics: Acetyl Coenzyme A; Adaptation, Physiological; Amino Acids; Antineoplastic Agents; Antioxidants; Autophagy; Blood Glucose; Energy Metabolism; Epigenomics; Fatty Acids; Genetic Heterogeneity; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Lipids; Mitochondria; Mitochondrial Ribosomes; Neoplasms; Nucleic Acids; Oxidative Stress; Pyruvic Acid; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Microenvironment | 2017 |
Multifactorial Effects on Different Types of Brain Cells Contribute to Ammonia Toxicity.
Topics: Ammonia; Animals; Astrocytes; Brain; Cyclic GMP; Energy Metabolism; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Lactic Acid; Liver Failure, Acute; Potassium; Pyruvic Acid; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 2 | 2017 |
Intraabdominal microdialysis - methodological challenges.
Topics: Abdominal Cavity; Diffusion; Digestive System Surgical Procedures; Extracellular Fluid; Glucose; Glycerol; Humans; Infusion Pumps; Lactic Acid; Membranes, Artificial; Microdialysis; Monitoring, Physiologic; Postoperative Care; Pyruvic Acid; Rheology | 2016 |
Hyperlactatemia and Cardiac Surgery.
Topics: Acidosis, Lactic; Biomarkers; Cardiac Surgical Procedures; Humans; Hyperlactatemia; Hypoxia; Lactic Acid; Metabolic Clearance Rate; Models, Cardiovascular; Oxygen; Pyruvic Acid | 2017 |
Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis Regulatory Proteins; Cell Proliferation; Drug Discovery; Fibroblasts; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Ketone Bodies; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasms; NF-kappa B; Phosphoric Monoester Hydrolases; Proto-Oncogene Proteins c-myc; Pyruvic Acid; Stromal Cells; Symporters | 2017 |
UVA, metabolism and melanoma: UVA makes melanoma hungry for metastasis.
Topics: Animals; Cell Survival; DNA Damage; Glucose; Glycolysis; Humans; Lactic Acid; Melanoma; Mitogen-Activated Protein Kinases; NADP; Neoplasm Invasiveness; Pentose Phosphate Pathway; Proto-Oncogene Proteins c-akt; Pyruvic Acid; Reactive Oxygen Species; Skin; Skin Neoplasms; Tumor Escape; Ultraviolet Rays | 2018 |
Metabolism of the oocyte and the preimplantation embryo: implications for assisted reproduction.
Topics: Blastocyst; Embryonic Development; Energy Metabolism; Female; Fertilization in Vitro; Genitalia, Female; Glucose; Humans; Lactic Acid; Oocytes; Pyruvic Acid; Reproductive Techniques, Assisted | 2018 |
Biomarkers for mitochondrial energy metabolism diseases.
Topics: Amino Acids; Biomarkers; Carnitine; Creatine Kinase; Energy Metabolism; Fibroblast Growth Factors; Growth Differentiation Factor 15; Humans; Lactic Acid; Mitochondrial Diseases; Oxidative Phosphorylation; Pyruvic Acid | 2018 |
Systematic review of the biological variation data for diabetes related analytes.
Topics: Adiponectin; Blood Glucose; C-Peptide; Diabetes Mellitus; Fructosamine; Glycated Hemoglobin; Humans; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Lactic Acid; Pyruvic Acid | 2019 |
Hypoxia/pseudohypoxia-mediated activation of hypoxia-inducible factor-1α in cancer.
Topics: Cell Hypoxia; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Neoplasms; Protein Stability; Pyruvic Acid; Signal Transduction | 2019 |
Metabolic Biomarkers in Nematode C. elegans During Aging.
Topics: Aging; Animals; Caenorhabditis elegans; Energy Metabolism; Lactic Acid; Mitochondria; Oxidative Phosphorylation; Pyruvic Acid | 2019 |
Quantitative Assessment of Blood Lactate in Shock: Measure of Hypoxia or Beneficial Energy Source.
Topics: Animals; Critical Illness; Disease Models, Animal; Dogs; Humans; Hypoxia; Lactic Acid; Liver; Models, Biological; Muscles; Pyruvic Acid; Sheep; Shock, Cardiogenic; Shock, Hemorrhagic; Shock, Septic; Swine | 2020 |
The metabolism of cancer cells during metastasis.
Topics: Acetates; Adenosine Triphosphate; Animals; Cell Plasticity; Fatty Acids; Glutamine; Humans; Lactic Acid; Neoplasm Metastasis; Neoplasms; Neoplastic Cells, Circulating; Pyruvic Acid | 2021 |
The anabolic role of the Warburg, Cori-cycle and Crabtree effects in health and disease.
Topics: Animals; Glucose; Glycolysis; Humans; Kidney; Lactic Acid; Liver; Muscle, Skeletal; Pyruvic Acid | 2021 |
Hyperpolarized MRI - An Update and Future Perspectives.
Topics: Bicarbonates; Carbon Isotopes; Humans; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid | 2022 |
The Impact of Short-Term Hyperoxia on Cerebral Metabolism: A Systematic Review and Meta-Analysis.
Topics: Brain Injuries; Glucose; Humans; Hyperoxia; Lactic Acid; Microdialysis; Observational Studies as Topic; Pyruvic Acid; Retrospective Studies | 2022 |
Laboratory and metabolic investigations.
Topics: Amino Acids; Humans; Lactic Acid; Mitochondria; Mitochondrial Diseases; Pyruvic Acid | 2023 |
CSF metabolomics alterations after aneurysmal subarachnoid hemorrhage: what do we know?
Topics: Biomarkers; Brain Ischemia; Humans; Lactic Acid; Pyruvic Acid; Subarachnoid Hemorrhage | 2023 |
Roles of malate and aspartate in gluconeogenesis in various physiological and pathological states.
Topics: Aspartic Acid; Gluconeogenesis; Glutamates; Lactic Acid; Malates; Pyruvic Acid | 2023 |
Hyperpolarised
Topics: Breast; Breast Neoplasms; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid | 2023 |
114 trial(s) available for lactic acid and pyruvic acid
| Article | Year |
|---|---|
Factors affecting the components of the alveolar CO2 output-O2 uptake relationship during incremental exercise in man.
Topics: Adolescent; Adult; Carbon Dioxide; Epinephrine; Exercise; Glycogen; Humans; Lactates; Lactic Acid; Male; Middle Aged; Norepinephrine; Oxygen Consumption; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid | 1992 |
Metabolic changes induced by maximal exercise in human subjects following L-carnitine administration.
Topics: Acetylcarnitine; Adult; Carnitine; Double-Blind Method; Exercise; Humans; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid | 1990 |
The [lactate]/[pyruvate] ratio and alcohol metabolism: experiments with naloxone in fasting normal male volunteers.
Topics: Adult; Alcoholic Intoxication; Ethanol; Humans; Lactates; Lactic Acid; Male; Metabolic Clearance Rate; Naloxone; Pyruvates; Pyruvic Acid | 1989 |
Metabolic response to different forms of physical exercise in type I diabetics and the duration of the glucose lowering effect.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Female; Hormones; Humans; Lactates; Lactic Acid; Male; Middle Aged; Neurotransmitter Agents; Physical Exertion; Pyruvates; Pyruvic Acid; Time Factors | 1985 |
Amantadine, fatigue, and multiple sclerosis.
Topics: Amantadine; beta-Endorphin; beta-Lipotropin; Disability Evaluation; Fatigue; Humans; Lactates; Lactic Acid; Multiple Sclerosis; Pyruvates; Pyruvic Acid | 1988 |
Increases in walking distance in patients with peripheral vascular disease treated with L-carnitine: a double-blind, cross-over study.
Topics: Carnitine; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Humans; Intermittent Claudication; Lactates; Lactic Acid; Leg; Male; Middle Aged; Muscles; Oxidative Phosphorylation; Pyruvates; Pyruvic Acid; Random Allocation; Regional Blood Flow | 1988 |
Effects of nifedipine on responses to exercise in normal subjects.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Blood Glucose; Blood Pressure; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Heart Rate; Humans; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Maximal Voluntary Ventilation; Middle Aged; Nifedipine; Norepinephrine; Physical Exertion; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid; Respiration; Time Factors; Triglycerides | 1985 |
The effects of four different crystalloid bypass pump-priming fluids upon the metabolic response to cardiac operation.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Cardiopulmonary Bypass; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Insulin; Isotonic Solutions; Lactates; Lactic Acid; Perfusion; Potassium; Potassium Compounds; Prospective Studies; Pyruvates; Pyruvic Acid; Random Allocation; Ringer's Lactate | 1985 |
A comparison of the effects of four intravenous solutions for the treatment of ketonuria during labour.
Topics: Female; Glucose; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; Ketone Bodies; Lactates; Lactic Acid; Obstetric Labor Complications; Osmolar Concentration; Pregnancy; Prospective Studies; Pyruvates; Pyruvic Acid; Random Allocation; Sodium Chloride; Thymol | 1985 |
Continuous intraperitoneal insulin infusion in the management of severely brittle diabetes--a metabolic and clinical comparison with intravenous infusion.
Topics: Adolescent; Adult; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Female; Humans; Insulin Infusion Systems; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Time Factors | 1984 |
Opiate receptors and the metabolic response to intravenous glucose.
Topics: Alanine; Blood Glucose; Chlorpropamide; Ethanol; Glucagon; Glucose; Humans; Insulin; Kinetics; Lactates; Lactic Acid; Naloxone; Pyruvates; Pyruvic Acid; Receptors, Opioid | 1982 |
Effects of ketamine anaesthesia on the metabolic response to pelvic surgery.
Topics: Adult; Anesthesia, Intravenous; Blood Glucose; Fallopian Tubes; Fatty Acids, Nonesterified; Female; Halothane; Hematocrit; Hemodynamics; Humans; Hydrocortisone; Intraoperative Period; Ketamine; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1984 |
Effect of pyridoxine-2-oxoglutarate administration in patients with advanced cirrhosis: control of ammonia pyruvate and lactate high plasma concentrations.
Topics: Amino Acids; Ammonia; Blood Glucose; Clinical Trials as Topic; Double-Blind Method; Humans; Lactates; Lactic Acid; Liver Cirrhosis; Pyridoxine; Pyruvates; Pyruvic Acid; Random Allocation | 1982 |
Treatment of pyruvic and lactic acidaemia in ophthalmoplegia plus.
Topics: Acidosis; Biopsy; Clinical Trials as Topic; Electromyography; Humans; Lactates; Lactic Acid; Microscopy, Electron; Muscles; Ophthalmoplegia; Pyridoxine; Pyruvates; Pyruvic Acid | 1982 |
Effect of postoperative nutrition on muscle high energy phosphates.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Aged; Bed Rest; Creatine; Energy Intake; Female; Food, Formulated; Hip Prosthesis; Humans; Lactates; Lactic Acid; Male; Middle Aged; Muscles; Phosphates; Phosphocreatine; Postoperative Care; Pyruvates; Pyruvic Acid | 1982 |
Serum levels of acetate and TCA cycle intermediates during hemodialysis in relation to symptoms.
Topics: Acetates; Adult; Citrates; Citric Acid; Citric Acid Cycle; Female; Humans; Isocitrates; Ketoglutaric Acids; Kidney Failure, Chronic; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Renal Dialysis | 1982 |
Xylitol-induced increase in the concentration of oxypurines and its mechanism.
Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytosol; Humans; Hypoxanthine; Hypoxanthines; Infusions, Intravenous; Inosine; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Middle Aged; NAD; Phosphates; Pyrazinamide; Pyruvates; Pyruvic Acid; Saline Solution, Hypertonic; Serum Albumin; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthines; Xylitol | 1995 |
Respiratory chain function in Leber's hereditary optic neuropathy: lack of correlation with clinical disease.
Topics: Adolescent; Adult; Aged; DNA; Electron Transport; Female; Fibroblasts; Humans; Lactates; Lactic Acid; Male; Middle Aged; Optic Atrophies, Hereditary; Oxidative Phosphorylation; Point Mutation; Polymerase Chain Reaction; Pyruvates; Pyruvic Acid | 1993 |
Effects of L- and DL-carnitine on patients with impaired exercise tolerance.
Topics: Administration, Oral; Aged; Cardiac Output; Carnitine; Exercise Test; Exercise Tolerance; Female; Heart Diseases; Hemodynamics; Humans; Lactates; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Pyruvates; Pyruvic Acid; Stereoisomerism | 1995 |
Isotopic determination of glycolytic flux during intense exercise in humans.
Topics: Adult; Anaerobiosis; Blood Glucose; Energy Metabolism; Exercise; Glycolysis; Humans; Lactates; Lactic Acid; Male; Oxygen Consumption; Pyruvates; Pyruvic Acid; Regression Analysis | 1995 |
Comparison of effects of yoga & physical exercise in athletes.
Topics: Adult; Exercise; Humans; Lactates; Lactic Acid; Male; Oxygen Consumption; Pyruvates; Pyruvic Acid; Respiration; Sports; Yoga | 1994 |
Effect of brief exercise on circulating insulin-like growth factor I.
Topics: Adult; Anaerobic Threshold; Blood Glucose; Exercise; Female; Growth Hormone; Humans; Insulin-Like Growth Factor I; Lactates; Lactic Acid; Male; Oxygen Consumption; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid; Somatostatin | 1994 |
Effect of infusing branched-chain amino acid during incremental exercise with reduced muscle glycogen content.
Topics: Adult; Amino Acids, Branched-Chain; Fasting; Glycogen; Humans; Infusions, Intravenous; Lactates; Lactic Acid; Male; Muscle, Skeletal; Physical Exertion; Pyruvates; Pyruvic Acid; Respiration | 1994 |
Efficacy of L-propionylcarnitine treatment in patients with left ventricular dysfunction.
Topics: Adult; Aged; Cardiotonic Agents; Carnitine; Double-Blind Method; Echocardiography, Doppler; Exercise Test; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Stroke Volume; Ventricular Dysfunction, Left | 1994 |
Alcohol tolerance in patients with non-insulin-dependent (type 2) diabetes treated with sulphonylurea derivatives.
Topics: Acetaldehyde; Adult; Aged; Blood Gas Analysis; Blood Glucose; Body Temperature Regulation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Ethanol; Female; Flushing; Hemodynamics; Humans; Hypoglycemic Agents; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Sulfonylurea Compounds | 1994 |
The effects of glucose on plasma amino acids and pyruvate during upper abdominal surgery.
Topics: Amino Acids; Blood Glucose; Fatty Acids, Nonesterified; Female; Gastrectomy; Glucose; Humans; Infusion Pumps; Insulin; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1993 |
Growth hormone treatment after abdominal surgery decreased carbohydrate oxidation and increased fat oxidation in patients with total parenteral nutrition.
Topics: Adult; Aged; Blood Glucose; Calorimetry; Digestive System Surgical Procedures; Double-Blind Method; Female; Forearm; Glucose; Growth Hormone; Humans; Lactates; Lactic Acid; Lipid Metabolism; Male; Middle Aged; Oxidation-Reduction; Parenteral Nutrition, Total; Pyruvates; Pyruvic Acid; Recombinant Proteins | 1993 |
Acute effects of high fat and high glucose meals on the growth hormone response to exercise.
Topics: Adult; Blood Glucose; Diet; Dietary Fats; Exercise; Female; Glucose; Growth Hormone; Hormones; Humans; Lactates; Lactic Acid; Male; Oxygen Consumption; Pyruvates; Pyruvic Acid; Time Factors | 1993 |
Metabolic and hormonal responses to induced hypotension for middle ear surgery.
Topics: Adult; Blood Glucose; Blood Pressure; Ear, Middle; Fatty Acids, Nonesterified; Female; Hormones; Humans; Hypotension, Controlled; Isoflurane; Lactates; Lactic Acid; Male; Middle Aged; Nitroprusside; Pyruvates; Pyruvic Acid; Trimethaphan; Uric Acid; Vasodilator Agents | 1996 |
Stöckert roller pump generated pulsatile flow: cerebral metabolic changes in adult cardiopulmonary bypass.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Blood Glucose; Brain; Brain Chemistry; Cardiopulmonary Bypass; Cerebrovascular Circulation; Coronary Artery Bypass; Equipment Design; Humans; Hydroxybutyrates; Lactic Acid; Male; Middle Aged; Pulsatile Flow; Pyruvic Acid; Vascular Resistance | 1997 |
Coenzyme Q10 treatment in mitochondrial encephalomyopathies. Short-term double-blind, crossover study.
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Coenzymes; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Follow-Up Studies; Humans; Lactic Acid; Male; Middle Aged; Mitochondrial Encephalomyopathies; Neurologic Examination; Physical Endurance; Pyruvic Acid; Ubiquinone | 1997 |
Enhancement of alcohol-induced hypoglycaemia by H2-receptor antagonists.
Topics: Acetaldehyde; Anti-Ulcer Agents; Blood Glucose; Cimetidine; Drug Synergism; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Hyperglycemia; Lactic Acid; Male; Pyruvic Acid; Ranitidine | 1997 |
The effect of sodium citrate ingestion on the metabolic response to intense exercise following diet manipulation in man.
Topics: Acid-Base Equilibrium; Adult; Basal Metabolism; Bicarbonates; Blood Glucose; Citrates; Diet; Energy Metabolism; Exercise; Exercise Test; Humans; Lactic Acid; Male; Oxygen Consumption; Pyruvic Acid; Sodium Citrate | 1997 |
Role of in vivo proton magnetic resonance spectroscopy in the diagnosis and management of brain abscesses.
Topics: Adolescent; Adult; Amino Acids; Brain; Brain Abscess; Child; Child, Preschool; Female; Humans; Infant; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyruvic Acid | 1998 |
Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM.
Topics: Adult; Alanine; Blood Glucose; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Diabetes Mellitus, Type 2; Fatty Acids; Female; Gluconeogenesis; Humans; Indicator Dilution Techniques; Kinetics; Lactic Acid; Liver; Male; Middle Aged; Oxidation-Reduction; Phosphoenolpyruvate; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 1998 |
Effects of spinal anaesthesia on metabolic processes.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Anesthesia, Spinal; Anesthetics, Local; Bicarbonates; Blood Gas Analysis; Blood Glucose; Carbon Dioxide; Female; Humans; Lactic Acid; Lidocaine; Male; Middle Aged; Monitoring, Intraoperative; Oxygen Consumption; Pyruvic Acid; Reference Values | 1998 |
[The effect of polarizing mixture KIG (potassium + insulin + glucose) on some metabolites of glucose transformation in patients with ischemic stroke during the earliest period of illness].
Topics: Aged; Drug Therapy, Combination; Glucose; Humans; Infusions, Intravenous; Insulin; Ischemic Attack, Transient; Lactic Acid; Potassium; Pyruvic Acid | 1997 |
Effect of glucose on the plasma concentration and urinary excretion of uridine and purine bases.
Topics: Adult; Blood Glucose; Glucagon; Glucose; Humans; Insulin; Lactic Acid; Male; Middle Aged; Phosphates; Purines; Pyruvic Acid; Uridine | 1999 |
Markers of splanchnic perfusion and intestinal translocation of endotoxins during cardiopulmonary bypass: effects of dopamine and milrinone.
Topics: Adult; Aged; Biological Transport; Cardiopulmonary Bypass; Dopamine; Endotoxemia; Endotoxins; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Lactic Acid; Middle Aged; Milrinone; Prospective Studies; Pyruvic Acid; Splanchnic Circulation | 1999 |
Effects of taurine on human embryo development in vitro.
Topics: Blastocyst; Cell Count; Cell Death; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Glutamine; Humans; Lactic Acid; Pyruvic Acid; Taurine | 1999 |
Effects of exposure to low concentrations of carbon monoxide on exercise performance and myocardial perfusion in young healthy men.
Topics: Adolescent; Adult; Carbon Monoxide; Carboxyhemoglobin; Coronary Circulation; Cross-Over Studies; Exercise; Humans; Lactic Acid; Male; Pyruvic Acid; Radionuclide Imaging | 1999 |
Pulmonary lactate release in patients with acute lung injury is not attributable to lung tissue hypoxia.
Topics: Biomarkers; Cell Hypoxia; Hemodynamics; Humans; Lactic Acid; Lung; Middle Aged; Prospective Studies; Pyruvic Acid; Respiration, Artificial; Respiratory Care Units; Respiratory Distress Syndrome; Severity of Illness Index | 1999 |
Effect of branched-chain amino acids on the plasma concentration of uridine does not occur via the action of glucagon or insulin.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Blood Glucose; Creatinine; Cyclic AMP; Glucagon; Humans; Insulin; Lactic Acid; Phosphates; Purines; Pyruvic Acid; Uridine | 2000 |
Epinephrine infusion during moderate intensity exercise increases glucose production and uptake.
Topics: Adult; Blood Glucose; Epinephrine; Exercise; Glucagon; Humans; Infusions, Intravenous; Insulin; Lactic Acid; Male; Metabolic Clearance Rate; Norepinephrine; Oxygen Consumption; Pyruvic Acid | 2000 |
Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet.
Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcarnitine; Adult; Blood Glucose; Dietary Carbohydrates; Exercise Test; Fatty Acids, Nonesterified; Food, Formulated; Glycerol; Glycerophosphates; Glycogen; Humans; Insulin; Lactic Acid; Male; Muscle, Skeletal; Physical Exertion; Protein Kinases; Protein Serine-Threonine Kinases; Pulmonary Gas Exchange; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reference Values | 2000 |
Pyruvate ingestion for 7 days does not improve aerobic performance in well-trained individuals.
Topics: Adult; Bicycling; Blood Gas Analysis; Blood Glucose; Cross-Over Studies; Diet; Double-Blind Method; Drinking; Exercise; Female; Humans; Insulin; Lactic Acid; Male; Oxygen Consumption; Peptides; Physical Fitness; Pyruvic Acid | 2000 |
Low-dose prostacyclin in treatment of severe brain trauma evaluated with microdialysis and jugular bulb oxygen measurements.
Topics: Adult; Aged; Biomarkers; Brain Injuries; Energy Metabolism; Epoprostenol; Female; Humans; Hypoxia; Jugular Veins; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Platelet Aggregation Inhibitors; Pyruvic Acid | 2000 |
Effect of creatine feeding on maximal exercise performance in vegetarians.
Topics: Adult; Blood Glucose; Creatine; Diet, Vegetarian; Exercise; Exercise Test; Humans; Lactic Acid; Male; Placebos; Pyruvic Acid | 2000 |
Carbohydrate ingestion prior to exercise augments the exercise-induced activation of the pyruvate dehydrogenase complex in human skeletal muscle.
Topics: Acetylcarnitine; Adenosine Triphosphate; Adult; Blood Glucose; Carnitine; Citric Acid; Dietary Carbohydrates; Enzyme Activation; Exercise; Exercise Test; Fatty Acids, Nonesterified; Glycogen; Humans; Insulin; Lactic Acid; Male; Muscle, Skeletal; Oxidative Phosphorylation; Oxygen; Oxygen Consumption; Phosphocreatine; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2000 |
Cerebral microdialysis monitoring: determination of normal and ischemic cerebral metabolisms in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain; Brain Death; Brain Ischemia; Cerebral Angiography; Extracellular Space; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Microdialysis; Middle Aged; Monitoring, Physiologic; Pyruvic Acid; Stroke; Subarachnoid Hemorrhage | 2000 |
Subcutaneous microdialysis in mitochondrial cytopathy.
Topics: Adult; Aged; Circadian Rhythm; Female; Glucose; Humans; Kidney Failure, Chronic; Lactic Acid; Male; Microdialysis; Middle Aged; Mitochondrial Myopathies; Point Mutation; Pyruvic Acid | 2001 |
Predictive value of neurochemical monitoring in large middle cerebral artery infarction.
Topics: Adult; Aged; Brain Edema; Critical Care; Electrodes, Implanted; Extracellular Space; Female; Frontal Lobe; Glutamic Acid; Glycerol; Humans; Infarction, Middle Cerebral Artery; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Predictive Value of Tests; Prognosis; Prospective Studies; Pyruvic Acid; Risk Assessment | 2001 |
Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise.
Topics: Acetates; Acetyl Coenzyme A; Acetylcarnitine; Adenosine Diphosphate; Adenosine Monophosphate; Adult; Exercise; Exercise Test; Glycolysis; Humans; Hyperoxia; Lactic Acid; Male; Muscle, Skeletal; Oxidative Phosphorylation; Oxygen Consumption; Phosphocreatine; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2001 |
The metabolic, catecholamine and cardiovascular effects of exercise in human sympathetic denervation.
Topics: 3-Hydroxybutyric Acid; Aged; Autonomic Nervous System Diseases; Blood Pressure; Catecholamines; Exercise; Fatty Acids, Nonesterified; Female; Glycerol; Glycolysis; Heart Rate; Hemodynamics; Humans; Lactic Acid; Lipolysis; Male; Middle Aged; Pyruvic Acid | 2001 |
Clinical cerebral microdialysis: brain metabolism and brain tissue oxygenation after acute brain injury.
Topics: Adolescent; Adult; Brain; Brain Injuries; Critical Care; Female; Glucose; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen; Pyruvic Acid | 2001 |
Effects of hypothermia on excitatory amino acids and metabolism in stroke patients: a microdialysis study.
Topics: Adult; Aged; Brain; Female; Glutamic Acid; Glycerol; Humans; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvic Acid; Regression Analysis; Survival Rate; Tomography, X-Ray Computed | 2002 |
Cerebral oxygen and microdialysis monitoring during aneurysm surgery: effects of blood pressure, cerebrospinal fluid drainage, and temporary clipping on infarction.
Topics: Adult; Aged; Blood Pressure; Cerebral Infarction; Cerebrospinal Fluid; Drainage; Female; Glucose; Glutamic Acid; Humans; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Intraoperative; Oxygen; Oxygen Consumption; Pyruvic Acid; Surgical Instruments | 2002 |
Microdialysis and electromyography of experimental muscle fatigue in healthy volunteers and patients with mitochondrial myopathy.
Topics: Aconitate Hydratase; Adolescent; Adult; Aged; Electromyography; Exercise; Female; Humans; Isometric Contraction; Lactic Acid; Male; Microdialysis; Mitochondrial Myopathies; Muscle Fatigue; Muscle, Skeletal; Pyruvic Acid; Succinate Dehydrogenase | 2002 |
Effect of beer on the plasma concentrations of uridine and purine bases.
Topics: Adult; Beer; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Ethanol; Freeze Drying; Humans; Hypoxanthine; Lactic Acid; Male; Middle Aged; Purines; Pyrimidines; Pyruvic Acid; Spectrophotometry, Ultraviolet; Uric Acid; Uridine; Xanthines | 2002 |
Effect of hyperventilation on extracellular concentrations of glutamate, lactate, pyruvate, and local cerebral blood flow in patients with severe traumatic brain injury.
Topics: Adult; Brain; Brain Injuries; Brain Ischemia; Female; Glutamic Acid; Humans; Hyperventilation; Lactic Acid; Male; Microdialysis; Prospective Studies; Pyruvic Acid; Regional Blood Flow; Respiration, Artificial; Time Factors | 2002 |
Assessment of the lower limit for cerebral perfusion pressure in severe head injuries by bedside monitoring of regional energy metabolism.
Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Brain Chemistry; Brain Injuries; Cerebrovascular Circulation; Child; Child, Preschool; Craniocerebral Trauma; Critical Care; Energy Metabolism; Female; Glucose; Hematoma, Subdural; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Point-of-Care Systems; Posture; Pyruvic Acid | 2003 |
Effects of oral creatine-pyruvate supplementation in cycling performance.
Topics: Bicycling; Creatine; Dietary Supplements; Double-Blind Method; Exercise Test; Humans; Lactic Acid; Male; Pyruvic Acid; Task Performance and Analysis | 2003 |
Effect of exercise and beer on the plasma concentration and urinary excretion of purine bases.
Topics: Adult; Ammonia; Beer; Central Nervous System Depressants; Creatinine; Ethanol; Exercise; Exercise Test; Humans; Hypoxanthine; Lactic Acid; Male; Purines; Pyruvic Acid; Uric Acid; Xanthine | 2003 |
Short-term training attenuates muscle TCA cycle expansion during exercise in women.
Topics: Adult; Alanine; Citrate (si)-Synthase; Citric Acid Cycle; Exercise; Female; Glutamic Acid; Glycogen; Heart Rate; Humans; Lactic Acid; Male; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Phosphocreatine; Physical Fitness; Pulmonary Gas Exchange; Pyruvic Acid; Sex Characteristics | 2003 |
A randomized, controlled trial of parenteral glutamine in ill, very low birth-weight neonates.
Topics: Amino Acids; Ammonia; Birth Weight; Enteral Nutrition; Female; Gestational Age; Glutamine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Lactic Acid; Liver Function Tests; Male; Parenteral Nutrition; Pyruvic Acid; Risk Factors; Time Factors; Urea | 2003 |
Pyruvate-enhanced cardioprotection during surgery with cardiopulmonary bypass.
Topics: Aged; Cardioplegic Solutions; Cardiopulmonary Bypass; Cardiotonic Agents; Catecholamines; Coronary Artery Bypass; Creatine Kinase; Female; Heart; Heart Arrest, Induced; Humans; Lactic Acid; Length of Stay; Male; Middle Aged; Myocardial Ischemia; Oxygen; Prospective Studies; Pyruvic Acid; Treatment Outcome; Troponin I; Ventricular Function, Left | 2003 |
Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study.
Topics: Adult; Aged; Biomarkers; Blood Flow Velocity; Brain; Brain Ischemia; Cerebrovascular Circulation; Extracellular Fluid; Female; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvic Acid; Sensitivity and Specificity; Subarachnoid Hemorrhage; Tomography, Emission-Computed; Vasospasm, Intracranial | 2004 |
Pyruvate shuttling during rest and exercise before and after endurance training in men.
Topics: Adult; Alanine; Anaerobic Threshold; Body Composition; Carbohydrate Metabolism; Exercise; Exercise Test; Femoral Artery; Femoral Vein; Gas Chromatography-Mass Spectrometry; Glycolysis; Hemodynamics; Humans; Lactic Acid; Male; Muscle, Skeletal; Physical Endurance; Physical Fitness; Pyruvic Acid; Rest | 2004 |
Poor-grade aneurysmal subarachnoid hemorrhage: relationship of cerebral metabolism to outcome.
Topics: Brain; Disability Evaluation; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Humans; Hyperglycemia; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Neurosurgical Procedures; Point-of-Care Systems; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage; Treatment Outcome | 2004 |
Postoperative on-line monitoring with intraperitoneal microdialysis is a sensitive clinical method for measuring increased anaerobic metabolism that correlates to the cytokine response.
Topics: Adult; Aged; Aged, 80 and over; Digestive System Surgical Procedures; Female; Humans; Interleukin-10; Lactic Acid; Male; Microdialysis; Middle Aged; Peritoneum; Postoperative Care; Pyruvic Acid; Sensitivity and Specificity; Tumor Necrosis Factor-alpha | 2004 |
Dichloroacetate treatment for mitochondrial cytopathy: long-term effects in MELAS.
Topics: Abdominal Pain; Administration, Oral; Adolescent; Chemical and Drug Induced Liver Injury; Child; Dichloroacetic Acid; Female; Headache; Humans; Hypocalcemia; Lactic Acid; MELAS Syndrome; Mitochondria; Muscle Weakness; Peripheral Nervous System Diseases; Pyruvic Acid; Stroke; Time Factors; Treatment Outcome | 2004 |
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study.
Topics: Acute Disease; Adolescent; Adult; Brain Injuries; Brain Ischemia; Glucose; Humans; Incidence; Lactic Acid; Longitudinal Studies; Microdialysis; Middle Aged; Positron-Emission Tomography; Prospective Studies; Pyruvic Acid; Reproducibility of Results | 2005 |
Influences of AT1 receptor blockade on tissue metabolism in obese men.
Topics: Adipose Tissue; Adult; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Energy Metabolism; Ethanol; Glycerol; Humans; Irbesartan; Isoproterenol; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Obesity; Pyruvic Acid; Receptor, Angiotensin, Type 1; Tetrazoles | 2006 |
Labeled CO(2) production and oxidative vs nonoxidative disposal of labeled carbohydrate administered at rest.
Topics: Adult; Animals; Calorimetry, Indirect; Carbon Dioxide; Carbon Isotopes; Carbon Radioisotopes; Citric Acid Cycle; Dietary Carbohydrates; Female; Gluconeogenesis; Glycogen; Humans; Lactic Acid; Liver; Male; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Rest; Urea | 2005 |
A single bout of exercise is followed by a prolonged decrease in the interstitial glucose concentration in skeletal muscle.
Topics: Adult; Analysis of Variance; Blood Glucose; Case-Control Studies; Ergometry; Exercise; Extracellular Space; Female; Glucose; Humans; Isometric Contraction; Lactic Acid; Leg; Male; Microdialysis; Muscle, Skeletal; Pyruvic Acid; Regional Blood Flow; Time Factors; Urea | 2005 |
Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise.
Topics: Adult; Blood Gas Analysis; Exercise; Glucose; Glycogenolysis; Humans; Hyperoxia; In Vitro Techniques; Lactic Acid; Leg; Male; Muscle, Skeletal; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Time Factors | 2006 |
Intracerebral microdialysis and intracranial compliance monitoring of patients with traumatic brain injury.
Topics: Adult; Brain Injuries; Coma; Compliance; Female; Fever; Glasgow Coma Scale; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Models, Statistical; Monitoring, Physiologic; Pyruvic Acid; Risk Factors; Severity of Illness Index | 2006 |
Influence of caffeine on perception of effort, metabolism and exercise performance following a high-fat meal.
Topics: Adult; Blood Glucose; Caffeine; Central Nervous System Stimulants; Dietary Carbohydrates; Dietary Fats; Exercise Test; Fatty Acids, Nonesterified; Glycerol; Heart Rate; Humans; Lactic Acid; Male; Oxygen Consumption; Physical Exertion; Pulmonary Ventilation; Pyruvic Acid | 2006 |
Frameless stereotactic aspiration and thrombolysis of deep intracerebral hemorrhage is associated with reduced levels of extracellular cerebral glutamate and unchanged lactate pyruvate ratios.
Topics: Brain; Cerebral Angiography; Cerebral Hemorrhage; Cerebral Ventricles; Female; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Prospective Studies; Pyruvic Acid; Stereotaxic Techniques; Thrombolytic Therapy; Tomography, X-Ray Computed | 2007 |
Alpha-tocopherol supplementation prevents the exercise-induced reduction of serum paraoxonase 1/arylesterase activities in healthy individuals.
Topics: Adolescent; alpha-Tocopherol; Antioxidants; Aryldialkylphosphatase; Basketball; Blood Pressure; Carboxylic Ester Hydrolases; Catecholamines; Creatine Kinase; Dietary Supplements; Exercise; Heart Rate; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lipid Peroxidation; Lipids; Male; Muscle Proteins; Oxidative Stress; Pyruvic Acid; Young Adult | 2009 |
Sevoflurane but not propofol increases interstitial glycolysis metabolites availability during tourniquet-induced ischaemia-reperfusion.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Glucose; Glycerol; Glycolysis; Humans; Ischemic Preconditioning; Knee Joint; Lactic Acid; Male; Methyl Ethers; Microdialysis; Middle Aged; Muscle, Skeletal; Propofol; Pyruvic Acid; Reperfusion Injury; Sevoflurane; Tourniquets | 2008 |
Peripheral tissue metabolism during off-pump versus on-pump coronary artery bypass graft surgery: the microdialysis study.
Topics: Aged; Anastomosis, Surgical; Biomarkers; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Coronary Disease; Extracellular Fluid; Female; Glucose; Glycerol; Heart Arrest, Induced; Humans; Intraoperative Period; Lactic Acid; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Pilot Projects; Prospective Studies; Pyruvic Acid; Statistics, Nonparametric | 2008 |
Effect of reducing the dose of stavudine on body composition, bone density, and markers of mitochondrial toxicity in HIV-infected subjects: a randomized, controlled study.
Topics: Adipose Tissue; Adult; Anti-HIV Agents; Body Composition; Bone Density; DNA, Mitochondrial; Female; Genotype; HIV Infections; Humans; Lactic Acid; Leukocytes, Mononuclear; Male; Middle Aged; Pyruvic Acid; Stavudine | 2008 |
Increase in cerebral aerobic metabolism by normobaric hyperoxia after traumatic brain injury.
Topics: Adult; Brain Injuries; Female; Humans; Hyperoxia; Lactic Acid; Male; Microdialysis; Middle Aged; Oxidation-Reduction; Oxygen Consumption; Oxygen Inhalation Therapy; Pyruvic Acid; Spectroscopy, Near-Infrared; Treatment Outcome | 2008 |
Myocardial metabolism assessed by microdialysis: a prospective randomized study in on- and off-pump coronary bypass surgery.
Topics: Aged; Biomarkers; Coronary Artery Bypass, Off-Pump; Energy Metabolism; Female; Glucose; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Myocardial Ischemia; Myocardium; Prospective Studies; Pyruvic Acid; Troponin T; Urea | 2010 |
Ventriculostomy for control of raised ICP in acute traumatic brain injury.
Topics: Adult; Blood Pressure; Brain Injuries; Cerebrospinal Fluid; Female; Glasgow Coma Scale; Humans; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen; Prospective Studies; Pyruvic Acid; Ventriculostomy | 2008 |
Effects of temperature changes on cerebral biochemistry in spontaneous intracerebral hematoma.
Topics: Adult; Aged; Analysis of Variance; Brain Chemistry; Brain Edema; Cerebral Hemorrhage; Female; Glutamic Acid; Humans; Hyperthermia, Induced; Hypothermia; Lactic Acid; Male; Middle Aged; Prospective Studies; Pyruvic Acid; Statistics, Nonparametric; Temperature | 2008 |
Thiamine supplementation increases serum thiamine and reduces pyruvate and lactate levels in burn patients.
Topics: Adolescent; Adult; Burns; Dietary Supplements; Enteral Nutrition; Humans; Lactic Acid; Male; Middle Aged; Models, Biological; Pyruvic Acid; Thiamine; Young Adult | 2010 |
Blood loss and endocrine responses in hypotensive anaesthesia with sodium nitroprusside and nitroglycerin for mandibular osteotomy.
Topics: Adult; Anesthesia, Dental; Anesthetics, Inhalation; Blood Gas Analysis; Blood Loss, Surgical; Carbon Dioxide; Female; Hemodynamics; Hormones; Humans; Hypotension, Controlled; Lactic Acid; Male; Mandible; Methyl Ethers; Nitroglycerin; Nitroprusside; Oral Surgical Procedures; Osteotomy; Oxygen; Pyruvic Acid; Sevoflurane; Vasodilator Agents; Young Adult | 2009 |
Peritoneal microdialysis. Early diagnosis of anastomotic leakage after low anterior resection for rectosigmoid cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Early Diagnosis; Female; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Peritoneal Dialysis; Postoperative Complications; Predictive Value of Tests; Pyruvic Acid; Rectal Neoplasms; Sigmoid Neoplasms | 2009 |
Blood lactate and pyruvate levels in the perioperative period of liver resection with Pringle maneuver.
Topics: Bile Ducts; Blood Loss, Surgical; Constriction; Female; Hepatectomy; Hepatic Artery; Humans; Hypoxia; Intraoperative Period; Lactic Acid; Male; Middle Aged; Oxygen; Portal Vein; Pyruvic Acid | 2010 |
Elevated muscle interstitial levels of pain-inducing substances in symptomatic muscles in patients with polymyalgia rheumatica.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Blood Sedimentation; Bradykinin; C-Reactive Protein; Dinoprostone; Female; Glucocorticoids; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Polymyalgia Rheumatica; Prednisolone; Pyruvic Acid; Quadriceps Muscle; Serotonin; Tritium; Water | 2011 |
Biochemical markers analyzed using microdialysis and traumatic brain injury outcomes.
Topics: Adult; Biomarkers; Brain Injuries; Critical Care; Female; Follow-Up Studies; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Predictive Value of Tests; Prognosis; Pyruvic Acid; Treatment Outcome | 2011 |
Metabolic and oxidative effects of sevoflurane and propofol in children undergoing surgery for congenital heart disease.
Topics: Adolescent; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Preschool; Female; Glutathione; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Lactic Acid; Male; Methyl Ethers; Oxidative Stress; Propofol; Prospective Studies; Pyruvic Acid; Sevoflurane; Thiobarbituric Acid Reactive Substances; Time Factors | 2011 |
Metabolic alterations in adipose tissue during the early phase of experimental endotoxemia in humans.
Topics: Adult; Biomarkers; Double-Blind Method; Endotoxemia; Glycerol; Glycolysis; Humans; Injections, Intravenous; Kinetics; Lactic Acid; Lipolysis; Lipopolysaccharides; Male; Microdialysis; Pyruvic Acid; Regional Blood Flow; Skin; Subcutaneous Fat; Thigh; Young Adult | 2011 |
Substrate oxidation and cardiac performance during exercise in disorders of long chain fatty acid oxidation.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase, Long-Chain; Adolescent; Adult; Child; Creatine Kinase; Demography; Exercise; Fatty Acids; Female; Glycolysis; Heart Function Tests; Heart Rate; Humans; Ketones; Lactic Acid; Lipid Metabolism, Inborn Errors; Male; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Respiration; Substrate Specificity; Young Adult | 2012 |
Cerebral microdialysis: perioperative monitoring and treatment of severe neurosurgical patient.
Topics: Brain Injuries; Glucose; Glycerol; Humans; Intracranial Hemorrhage, Traumatic; Lactic Acid; Microdialysis; Monitoring, Intraoperative; Pyruvic Acid; Subarachnoid Hemorrhage, Traumatic | 2011 |
Cerebral microdialysis effects of propofol versus midazolam in severe traumatic brain injury.
Topics: Adult; Biomarkers; Brain Chemistry; Brain Injuries; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hypnotics and Sedatives; Lactic Acid; Male; Microdialysis; Midazolam; Neuroprotective Agents; Propofol; Pyruvic Acid; Single-Blind Method | 2012 |
Metabolic activity in early tendon repair can be enhanced by intermittent pneumatic compression.
Topics: Achilles Tendon; Adolescent; Adult; Aged; Casts, Surgical; Female; Glucose; Glutamic Acid; Humans; Immobilization; Intermittent Pneumatic Compression Devices; Lactic Acid; Male; Microdialysis; Middle Aged; Orthopedics; Postoperative Care; Pyruvic Acid; Rupture; Tendon Injuries; Wound Healing; Young Adult | 2012 |
Association of lower habitual physical activity level with mitochondrial and endothelial dysfunction in patients with stable coronary artery disease.
Topics: Aged; Blood Glucose; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Lactic Acid; Life Style; Lipids; Male; Middle Aged; Mitochondria; Motor Activity; Pyruvic Acid; Risk Factors | 2012 |
Experimental myalgia induced by repeated infusion of acidic saline into the human masseter muscle does not cause the release of algesic substances.
Topics: Acids; Adult; Female; Glucose; Glutamic Acid; Humans; Hyperalgesia; Lactic Acid; Male; Masseter Muscle; Microdialysis; Muscular Diseases; Pain Measurement; Physical Stimulation; Pyruvic Acid; Serotonin; Severity of Illness Index; Single-Blind Method | 2013 |
A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury.
Topics: Body Temperature; Brain Injuries; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Intracranial Pressure; Lactic Acid; Microdialysis; Oximetry; Pilot Projects; Propofol; Prospective Studies; Pyruvic Acid; Respiration, Artificial; Trauma Severity Indices | 2012 |
Extracellular brain pH with or without hypoxia is a marker of profound metabolic derangement and increased mortality after traumatic brain injury.
Topics: Adult; Biomarkers; Brain; Brain Injuries; Disease-Free Survival; Female; Glucose; Humans; Hydrogen-Ion Concentration; Hypoxia, Brain; Lactic Acid; Male; Middle Aged; Pyruvic Acid; Survival Rate | 2013 |
Experimental tooth clenching. A model for studying mechanisms of muscle pain.
Topics: Adult; Bruxism; Case-Control Studies; Cross-Over Studies; Female; Follow-Up Studies; Glutamic Acid; Humans; Hyperalgesia; Lactic Acid; Male; Masseter Muscle; Microdialysis; Muscle Contraction; Muscle Fatigue; Pain Measurement; Pain Threshold; Proprioception; Pyruvic Acid; Regional Blood Flow; Reproducibility of Results; Research Design; Serotonin; Single-Blind Method; Temporomandibular Joint Dysfunction Syndrome; Vibration | 2013 |
Pain and intramuscular release of algesic substances in the masseter muscle after experimental tooth-clenching exercises in healthy subjects.
Topics: Adult; Bite Force; Bruxism; Chi-Square Distribution; Cross-Over Studies; Facial Pain; Female; Glutamic Acid; Humans; Jaw; Lactic Acid; Male; Masseter Muscle; Microdialysis; Muscle Contraction; Muscle Fatigue; Pyruvic Acid; Serotonin; Single-Blind Method; Statistics, Nonparametric; Young Adult | 2013 |
Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain.
Topics: Adult; Brain; Brain Injuries, Traumatic; Energy Metabolism; Female; Frontal Lobe; Glucose; Humans; Infusions, Intravenous; Lactic Acid; Male; Microdialysis; Middle Aged; Neuroprotection; Prospective Studies; Pyruvic Acid; Respiration, Artificial; Sodium Lactate; Time Factors | 2014 |
Moderate intra-abdominal hypertension leads to anaerobic metabolism in the rectus abdominis muscle tissue of critically ill patients: a prospective observational study.
Topics: Adult; Anaerobiosis; Critical Illness; Female; Glutamic Acid; Humans; Intra-Abdominal Hypertension; Lactic Acid; Male; Pyruvic Acid; Rectus Abdominis | 2014 |
Influence of skin incision position on physiological and biochemical changes in tissue after primary total knee replacement - a prospective randomised controlled trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Dermatologic Surgical Procedures; Extracellular Fluid; Female; Glucose; Humans; Lactic Acid; Male; Middle Aged; Osteoarthritis, Knee; Prospective Studies; Pyruvic Acid; Regional Blood Flow; Skin; Surgical Flaps; Wound Healing | 2015 |
Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio.
Topics: Adult; Blood Glucose; Brain Injuries, Traumatic; Energy Metabolism; Female; Humans; Imaging, Three-Dimensional; Infusions, Intravenous; Lactic Acid; Male; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid; Sodium Lactate; Tomography, X-Ray Computed; Young Adult | 2016 |
Acute Consumption of Flavan-3-ol-Enriched Dark Chocolate Affects Human Endogenous Metabolism.
Topics: Amino Acids; Chocolate; Creatinine; Cross-Over Studies; Female; Flavonoids; Humans; Lactic Acid; Male; Metabolome; Metabolomics; Phenylacetates; Phytochemicals; Postprandial Period; Pyruvic Acid; Sex Factors | 2017 |
Evolution of Energy Related Metabolites in Plasma from Newborns with Hypoxic-Ischemic Encephalopathy during Hypothermia Treatment.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Biomarkers; Case-Control Studies; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Ketone Bodies; Lactic Acid; Limit of Detection; Male; Pyruvic Acid | 2017 |
Design paper of the "Blood pressure targets in post-resuscitation care and bedside monitoring of cerebral energy state: a randomized clinical trial".
Topics: Blood Pressure; Brain; Cardiopulmonary Resuscitation; Double-Blind Method; Energy Metabolism; Humans; Lactic Acid; Microdialysis; Out-of-Hospital Cardiac Arrest; Pyruvic Acid; Research Design | 2019 |
Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study.
Topics: Adult; Antilymphocyte Serum; Catheters, Indwelling; Early Diagnosis; Feasibility Studies; Female; Glucose; Glycerol; Graft Rejection; Hematoma; Humans; Immunosuppressive Agents; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Mycophenolic Acid; Pancreas Transplantation; Pyruvic Acid; Tacrolimus; Venous Thrombosis | 2021 |
Bedside microdialysis for detection of early brain injury after out-of-hospital cardiac arrest.
Topics: Adult; Aged; Biomarkers; Brain; Brain Injuries; Brain Ischemia; Cerebral Veins; Energy Metabolism; Feasibility Studies; Female; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Out-of-Hospital Cardiac Arrest; Oxygen; Prospective Studies; Pyruvic Acid | 2021 |
2502 other study(ies) available for lactic acid and pyruvic acid
| Article | Year |
|---|---|
Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity.
Topics: Acetoacetates; Aldehyde-Lyases; Animals; Crystallography, X-Ray; Humans; Multienzyme Complexes; Protein Structure, Quaternary; Pyruvic Acid; Rabbits | 2012 |
Regulation of ATP sensitive potassium channel of isolated guinea pig ventricular myocytes by sarcolemmal monocarboxylate transport.
Topics: 2,4-Dinitrophenol; Acetates; Adenosine Triphosphate; Animals; Coumaric Acids; Cyanides; Dinitrophenols; Guinea Pigs; Heart Ventricles; Lactates; Lactic Acid; Membrane Potentials; Myocardium; Potassium Channels; Pyruvates; Pyruvic Acid; Sarcolemma | 1992 |
A patient with severe iron-deficiency anemia and memory disturbance.
Topics: Anemia, Hypochromic; Diet; Female; Humans; Intelligence; Iron; Lactates; Lactic Acid; Memory Disorders; Middle Aged; Psychological Tests; Pyruvates; Pyruvic Acid | 1992 |
[Cerebral lactate and pyruvate metabolism in infantile spasms].
Topics: Adrenocorticotropic Hormone; Brain; Humans; Infant; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Spasms, Infantile | 1992 |
Prenatal diagnosis of systemic disorders of the respiratory chain in cultured amniocytes and chorionic villus fibroblasts by studying the formation of lactate and pyruvate from glucose.
Topics: Amnion; Cells, Cultured; Chorionic Villi; Cytochrome-c Oxidase Deficiency; Female; Fibroblasts; Glucose; Humans; Infant, Newborn; Lactates; Lactic Acid; Male; Metabolism, Inborn Errors; Mitochondria; Oxidative Phosphorylation; Pregnancy; Prenatal Diagnosis; Pyruvates; Pyruvic Acid | 1992 |
Variable presentation of cytochrome c oxidase deficiency.
Topics: Cytochrome-c Oxidase Deficiency; Female; Humans; Infant, Newborn; Lactates; Lactic Acid; Male; Metabolism, Inborn Errors; Pyruvates; Pyruvic Acid | 1992 |
Concentrations of energy substrates in oviductal fluid and blood plasma of pigs during the peri-ovulatory period.
Topics: Analysis of Variance; Animals; Blood Glucose; Estrus; Fallopian Tubes; Female; Follicular Phase; Glucose; Lactates; Lactic Acid; Luteal Phase; Ovulation; Pyruvates; Pyruvic Acid; Swine | 1992 |
Exercise intolerance in patients with McArdle's disease or mitochondrial myopathies.
Topics: Adult; Alanine; Ammonia; Energy Metabolism; Exercise Test; Exercise Tolerance; Female; Glycogen Storage Disease Type V; Humans; Lactates; Lactic Acid; Male; Mitochondrial Myopathies; Muscle Contraction; Muscles; Oxygen Consumption; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid | 1992 |
In vivo effect of glucocorticoids on the rates of pyruvate utilization and lactate formation by incubated lymphocytes.
Topics: Animals; Glucocorticoids; Lactates; Lactic Acid; Lymphocytes; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Stress, Physiological | 1992 |
T4+ cell numbers are correlated with plasma glutamate and cystine levels: association of hyperglutamataemia with immunodeficiency in diseases with different aetiologies.
Topics: CD4-Positive T-Lymphocytes; Cystine; Glutamates; Glutamic Acid; HIV Seropositivity; HIV-1; Humans; Immunologic Deficiency Syndromes; Lactates; Lactic Acid; Leukocyte Count; Lung Neoplasms; Pyruvates; Pyruvic Acid | 1992 |
Glutamine and glucose metabolism in bovine blood lymphocytes.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Blood Glucose; Cattle; Glutamates; Glutamic Acid; Glutamine; Humans; In Vitro Techniques; Lactates; Lactic Acid; Lymphocytes; Male; Pyruvates; Pyruvic Acid; Rats | 1992 |
The effect of estrous cycle and buthionine sulfoximine on glutathione release from the in vitro perfused rat ovary.
Topics: Animals; Buthionine Sulfoximine; Estrus; Female; Glutamate-Cysteine Ligase; Glutathione; In Vitro Techniques; Lactates; Lactic Acid; Methionine Sulfoximine; Ovary; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1992 |
Lindane-induced changes in carbohydrate metabolism in Anguilla anguilla.
Topics: Anguilla; Animals; Carbohydrate Metabolism; Glucose; Glycogen; Hexachlorocyclohexane; Lactates; Lactic Acid; Liver; Muscles; Pyruvates; Pyruvic Acid | 1992 |
Use of arterialized venous blood sampling during incremental exercise tests.
Topics: Adult; Arteries; Blood Specimen Collection; Carbon Dioxide; Epinephrine; Evaluation Studies as Topic; Exercise; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Potassium; Pyruvates; Pyruvic Acid; Veins | 1992 |
Interactions between gluconeogenesis and fatty acid oxidation in isolated sheep hepatocytes.
Topics: Animals; Butyrates; Butyric Acid; Caproates; Carnitine O-Palmitoyltransferase; Epoxy Compounds; Fatty Acids; Gluconeogenesis; Lactates; Lactic Acid; Liver; Mitochondria, Liver; Oxidation-Reduction; Propionates; Pyruvates; Pyruvic Acid; Sheep | 1992 |
Metabolic effects of 4-pentenoate on isolated dog kidney tubules.
Topics: Animals; Dogs; Fatty Acids, Monounsaturated; In Vitro Techniques; Ketoglutaric Acids; Kidney Cortex; Kidney Tubules, Proximal; Lactates; Lactic Acid; Loop of Henle; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1992 |
On the mechanism of stimulation of ureagenesis by gluconeogenic substrates: role of pyruvate carboxylase.
Topics: Ammonium Chloride; Animals; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Male; Ornithine; Osmolar Concentration; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Substrate Specificity; Urea | 1992 |
Effects of sodium L-lactate and sodium racemic lactate on intraoperative acid-base status.
Topics: Acid-Base Equilibrium; Adult; Aged; Anesthesia, General; Female; Humans; Intraoperative Period; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Stereoisomerism; Tympanoplasty | 1992 |
The effects of ibuprofen enantiomers on hepatocyte intermediary metabolism and mitochondrial respiration.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Hydroxybutyrates; Ibuprofen; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Stereoisomerism | 1992 |
Exercise tolerance in panic disorder patients.
Topics: Adult; Arousal; Bicarbonates; Carbon Dioxide; Epinephrine; Exercise Test; Female; Heart Rate; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Norepinephrine; Oxygen; Panic; Panic Disorder; Pyruvates; Pyruvic Acid | 1992 |
Resolution of the subcellular site of very long-chain fatty acid beta-oxidation in human skin fibroblasts using a novel approach.
Topics: Adenosine Triphosphate; Carnitine O-Palmitoyltransferase; Cells, Cultured; Electron Transport; Epoxy Compounds; Fatty Acids; Fibroblasts; Glucose; Humans; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Skin; Subcellular Fractions | 1992 |
Metabolic effects of diltiazem in the perfused rat liver.
Topics: Animals; Atractyloside; Diltiazem; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Methotrexate; Norepinephrine; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1992 |
Exhaustive physical exercise causes oxidation of glutathione status in blood: prevention by antioxidant administration.
Topics: Animals; Antioxidants; Enzymes; Glutathione; Humans; Lactates; Lactic Acid; Male; Oxidation-Reduction; Physical Exertion; Pyruvates; Pyruvic Acid; Rats | 1992 |
Glucose turnover and its regulation during intense exercise and recovery in normal male subjects.
Topics: Adult; Blood Glucose; Epinephrine; Exercise; Glucagon; Homeostasis; Humans; Insulin; Kinetics; Lactates; Lactic Acid; Male; Metabolic Clearance Rate; Norepinephrine; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1992 |
Bite-force development, metabolic and circulatory response to electrical stimulation in the canine and porcine masseter muscles.
Topics: Animals; Bite Force; Dogs; Electric Stimulation; Energy Metabolism; Female; Glucose; Glycogen; Lactates; Lactic Acid; Masseter Muscle; Muscle Contraction; Oxygen Consumption; Phosphocreatine; Pyruvates; Pyruvic Acid; Swine | 1992 |
Effects of inhibitors of gluconeogenesis on weak organic acid uptake in rat renal tubules.
Topics: Acetates; Animals; Carboxylic Acids; Citric Acid Cycle; Coumaric Acids; Fluorescein; Fluoresceins; Gluconeogenesis; Kidney Tubules, Proximal; Lactates; Lactic Acid; Malates; Male; Phenylpyruvic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1992 |
Effect of epinephrine on glucose metabolism and hydrogen peroxide content in incubated rat macrophages.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Citrate (si)-Synthase; Epinephrine; Glucose; Glucosephosphate Dehydrogenase; Hexokinase; Hydrogen Peroxide; Ketoglutaric Acids; Kinetics; Lactates; Lactic Acid; Macrophage Activation; Macrophages; Male; Peritoneal Cavity; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Stimulation, Chemical | 1992 |
Effects of topically applied sulphur mustard on tissue glycogen, blood glucose, lactate and pyruvate in mice.
Topics: Administration, Topical; Animals; Blood Glucose; Brain Chemistry; Glycogen; Lactates; Lactic Acid; Liver; Male; Mice; Muscles; Mustard Gas; Pyruvates; Pyruvic Acid | 1992 |
Effects of a 1-yr stay at altitude on ventilation, metabolism, and work capacity.
Topics: Adult; Altitude; Carbon Dioxide; Exercise Test; Humans; Hypercapnia; Lactates; Lactic Acid; Male; Metabolism; Oxygen Consumption; Physical Endurance; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid; Respiratory Function Tests; Respiratory Mechanics | 1992 |
Effects of insulin and exercise on rat hindlimb muscles after simulated microgravity.
Topics: Animals; Body Weight; Carbon Dioxide; Drinking; Eating; Glucose; Glucosephosphates; Glycogen; Hindlimb; Insulin; Lactates; Lactic Acid; Male; Muscles; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Weightlessness | 1992 |
Concentrations of D-lactate and its related metabolic intermediates in liver, blood, and muscle of diabetic and starved rats.
Topics: Animals; Blood Chemical Analysis; Blood Glucose; Diabetes Mellitus, Experimental; Enzymes; Food Deprivation; Lactates; Lactic Acid; Liver; Male; Muscles; Pyruvaldehyde; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Streptozocin | 1992 |
D-lactate concentrations in blood, urine and sweat before and after exercise.
Topics: Adult; Energy Metabolism; Exercise Therapy; Humans; Lactates; Lactic Acid; Male; Physical Exertion; Pyruvaldehyde; Pyruvates; Pyruvic Acid; Running; Sodium; Sweat | 1992 |
Brain energy metabolites in mice intoxicated with acrylamide: effects of ischemia.
Topics: Acrylamide; Acrylamides; Adenosine Triphosphate; Animals; Body Weight; Brain; Brain Ischemia; Energy Metabolism; Glucose; Lactates; Lactic Acid; Male; Mice; Mice, Inbred Strains; Phosphocreatine; Pyruvates; Pyruvic Acid | 1992 |
Mechanisms for plasma-mediated activation of human blood cell aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Enzyme Activation; Erythrocytes; Gas Chromatography-Mass Spectrometry; Glucose; Humans; Lactates; Lactic Acid; Leukocytes; Magnetic Resonance Spectroscopy; Plasma; Pyruvates; Pyruvic Acid | 1992 |
Clinical aspects of mitochondrial disorders.
Topics: Child, Preschool; Coma; Diabetes Mellitus; DNA, Mitochondrial; Dwarfism; Female; Heart Diseases; Humans; Infant; Infant, Newborn; Ketone Bodies; Kidney Diseases; Lactates; Lactic Acid; Liver Diseases; Male; Metabolism, Inborn Errors; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Pancytopenia; Pyruvates; Pyruvic Acid | 1992 |
Ethanol stimulates glycogenolysis in livers from fed rats.
Topics: Animals; Ethanol; Fructosephosphates; Glucose; Glucose-6-Phosphate; Glucosephosphates; Insulin; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Pyruvates; Pyruvic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains | 1992 |
Effect of physostigmine on plasma lactate and pyruvate in untrained/trained rats.
Topics: Animals; Lactates; Lactic Acid; Male; Physical Conditioning, Animal; Physical Exertion; Physostigmine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1992 |
Reversible and irreversible oxidant injury to PC12 cells by hydrogen peroxide.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Death; Free Radicals; Glycolysis; Hydrogen Peroxide; Lactates; Lactic Acid; Mitochondria; Palmitic Acid; Palmitic Acids; PC12 Cells; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats | 1992 |
Effects of dichloroacetate on hemodynamic responses to dynamic exercise in dogs.
Topics: Adaptation, Physiological; Animals; Cardiac Output; Dichloroacetic Acid; Dogs; Epinephrine; Hemodynamics; Lactates; Lactic Acid; Male; Norepinephrine; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid | 1992 |
Effect of six organic acids on staphylococcal growth and enterotoxin production.
Topics: Acetates; Acetic Acid; Ascorbic Acid; Carboxylic Acids; Citrates; Citric Acid; Enterotoxins; Enzyme-Linked Immunosorbent Assay; Food Microbiology; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Propionates; Pyruvates; Pyruvic Acid; Staphylococcus aureus | 1992 |
Postanoxic oxidative injury in rat hepatocytes: lactate-dependent protection against tert-butylhydroperoxide.
Topics: Animals; Free Radicals; Hypoxia; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; NAD; Oxidants; Peroxides; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide | 1992 |
Is the anaerobic threshold truly anaerobic?
Topics: Acidosis, Lactic; Anaerobic Threshold; Anaerobiosis; Exercise; Exercise Test; Humans; Lactates; Lactic Acid; Oxygen Consumption; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid; Time Factors | 1992 |
Is Parkinson's disease a mitochondrial disorder?
Topics: Aerobiosis; Aged; Blotting, Southern; DNA, Mitochondrial; Exercise Test; Humans; Lactates; Lactic Acid; Middle Aged; Mitochondria, Muscle; Oxygen Consumption; Parkinson Disease; Pyruvates; Pyruvic Acid | 1992 |
Nonproductive exchanges: the use of isotopes gone astray.
Topics: Animals; Carbon Radioisotopes; Humans; Lactates; Lactic Acid; Metabolism; Muscles; Pyruvates; Pyruvic Acid; Radioisotopes | 1992 |
The Rett syndrome and CSF lactic acid patterns.
Topics: Acid-Base Equilibrium; Adult; Child; Child, Preschool; Citrates; Female; Humans; Lactates; Lactic Acid; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rett Syndrome | 1992 |
Effects of birth asphyxia on urinary organic acid excretion.
Topics: 3-Hydroxybutyric Acid; Acids; Aconitic Acid; Apgar Score; Asphyxia Neonatorum; Creatinine; Fetal Distress; Humans; Hydrogen-Ion Concentration; Hydroxybutyrates; Infant, Newborn; Keto Acids; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Valerates; Vanilmandelic Acid | 1992 |
Effect of thyroid hormone treatment on redox and phosphate potentials in rat liver.
Topics: Animals; Cytosol; Glyceric Acids; Glycerophosphates; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Male; Mitochondria, Liver; Oxidation-Reduction; Phosphates; Phospholipids; Pyruvates; Pyruvic Acid; Rats; Triiodothyronine | 1992 |
Effect of low and high intensity exercise on circulating growth hormone in men.
Topics: Adolescent; Adult; Blood Glucose; Epinephrine; Exercise; Growth Hormone; Humans; Insulin; Lactates; Lactic Acid; Male; Norepinephrine; Oxygen; Pyruvates; Pyruvic Acid | 1992 |
Myocardial carbohydrate, ketone, and fatty acid uptake in conscious lambs with aortopulmonary shunts.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Aortopulmonary Septal Defect; Biological Transport, Active; Fatty Acids, Nonesterified; Glucose; Hydroxybutyrates; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid; Sheep; Triglycerides | 1992 |
Alpha-ketoglutarate dehydrogenase deficiency presenting as congenital lactic acidosis.
Topics: Acidosis, Lactic; Humans; Infant, Newborn; Ketoglutarate Dehydrogenase Complex; Ketone Bodies; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Recurrence | 1992 |
Role of the rat liver in the disposal of a glucose gavage.
Topics: Alanine; Animals; Glucose; Intubation, Gastrointestinal; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1992 |
[Improving effect of the synthetic protease inhibitor E-3123 on experimental DIC in dogs].
Topics: Animals; Blood Coagulation Tests; Disease Models, Animal; Disseminated Intravascular Coagulation; Dogs; Gabexate; Guanidines; Hemodynamics; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid | 1992 |
Pyruvate and lactate metabolism in livers of guinea pigs perfused with chelating agents after repeated treatment with As2O3.
Topics: Animals; Antidotes; Arsenic; Arsenic Trioxide; Arsenicals; Chelating Agents; Dimercaprol; Guinea Pigs; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxides; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Succimer | 1991 |
[The comparative characteristics of the hemodynamic and biochemical indices of the postischemic period in relation to the regimens of brain autohemoperfusion].
Topics: Animals; Blood Glucose; Brain; Cats; Female; Hemodynamics; Hemoperfusion; Ischemic Attack, Transient; Lactates; Lactic Acid; Male; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1991 |
[Delayed manifestation of mitochondrial myopathy--complex I and IV deficiency of the mitochondrial respiratory chain with progressive paresis].
Topics: Biopsy; Cytochrome-c Oxidase Deficiency; Electromyography; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria, Muscle; Muscles; Muscular Atrophy; NAD(P)H Dehydrogenase (Quinone); Neurologic Examination; Neuromuscular Diseases; Paralysis; Pyruvates; Pyruvic Acid | 1991 |
[Uncoupling expression of genes coding for the synthesis of proteins involved in transport and utilization of fructose in Escherichia coli K-12].
Topics: Alanine; Bacterial Proteins; Biological Transport; Escherichia coli; Fructose; Gene Expression Regulation, Bacterial; Genes, Bacterial; Lactates; Lactic Acid; Mutation; Operon; Phosphotransferases; Phosphotransferases (Paired Acceptors); Pyruvates; Pyruvic Acid; Xylitol | 1991 |
Influence of pregnancy and lactation on diurnal and seasonal changes in lactic acid and pyruvic acid levels and in values of pH, pCO2 and pO2 in the mare blood.
Topics: Animals; Carbon Dioxide; Circadian Rhythm; Female; Horses; Hydrogen-Ion Concentration; Lactates; Lactation; Lactic Acid; Oxygen; Pregnancy; Pregnancy, Animal; Pyruvates; Pyruvic Acid; Seasons | 1991 |
Diurnal changes in lactic and pyruvic acid levels and pH values in foals during the first 13 weeks of their life and in their lactating mothers.
Topics: Animals; Animals, Newborn; Circadian Rhythm; Female; Horses; Hydrogen-Ion Concentration; Lactates; Lactation; Lactic Acid; Pregnancy; Pyruvates; Pyruvic Acid | 1991 |
The recovery from the relaxant effect by ouabain and the metabolic dependency of K+ contractions in guinea-pig taenia coli.
Topics: Animals; Colon; Guinea Pigs; Hydrogen-Ion Concentration; Isotonic Solutions; Kinetics; Lactates; Lactic Acid; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Osmolar Concentration; Ouabain; Potassium; Pyruvates; Pyruvic Acid; Sodium | 1991 |
[Pyruvate metabolism using stable isotopes].
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Dogs; Energy Metabolism; Lactates; Lactic Acid; Mass Spectrometry; Oxygen; Pyruvates; Pyruvic Acid | 1990 |
Calcium transport in bovine sperm mitochondria: effect of substrates and phosphate.
Topics: Animals; Bicarbonates; Biological Transport; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Filipin; Glutamates; Glutamic Acid; Glycerophosphates; Hydroquinones; Kinetics; Lactates; Lactic Acid; Malates; Male; Malonates; Mitochondria; Oxygen Consumption; Phosphates; Pyruvates; Pyruvic Acid; Ruthenium Red; Spermatozoa; Succinates; Succinic Acid | 1990 |
The effect of time on physiological changes in eel Anguilla anguilla, induced by lindane.
Topics: Anguilla; Animals; Gills; Glucose; Glycogen; Hexachlorocyclohexane; Lactates; Lactic Acid; Lipid Metabolism; Pyruvates; Pyruvic Acid; Time Factors; Water Pollutants, Chemical | 1991 |
Kinetic comparison of caiman epsilon-crystallin and authentic lactate dehydrogenases of vertebrates.
Topics: Alligators and Crocodiles; Animals; Chickens; Crystallins; Ducks; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lens, Crystalline; Muscles; Myocardium; NAD; Nitroblue Tetrazolium; Pyruvates; Pyruvic Acid; Staining and Labeling; Swine | 1991 |
Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis.
Topics: Adult; Amino Acids; Craniocerebral Trauma; Critical Care; Dialysis; Female; Frontal Lobe; Humans; Hypoxanthine; Hypoxanthines; Intracranial Pressure; Lactates; Lactic Acid; Male; Monitoring, Physiologic; Pyruvates; Pyruvic Acid; Subarachnoid Hemorrhage | 1992 |
Inhibition of gluconeogenesis by extracellular ATP in isolated rat hepatocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fructose; Gluconeogenesis; Glycerol; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
[Biochemical and anatomic changes in the muscles after leg bone lengthening by the Ilizarov method].
Topics: Adenosine Triphosphate; Adult; Bone Lengthening; Energy Metabolism; Female; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Leg; Leg Length Inequality; Male; Muscles; Pyruvates; Pyruvic Acid | 1991 |
Availability of energy substrates during liver regeneration in malnourished rats.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Lactates; Lactic Acid; Liver; Liver Glycogen; Liver Regeneration; Male; Nutrition Disorders; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
Glucose and glutamine metabolism in rat macrophages: enhanced glycolysis and unaltered glutaminolysis in spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Female; Glucose; Glutamates; Glutamine; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Macrophages; Pentose Phosphate Pathway; Peritoneal Cavity; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred BB | 1991 |
The roles of pyruvate, lactate and glucose during preimplantation development of embryos from F1 hybrid mice in vitro.
Topics: Animals; Blastocyst; Cells, Cultured; Culture Media; Embryonic and Fetal Development; Glucose; Hybridization, Genetic; Lactates; Lactic Acid; Mice; Mice, Inbred Strains; Pyruvates; Pyruvic Acid | 1991 |
[Biochemical modifications in stress ischemia of the calf muscles].
Topics: Alanine; Ammonia; Energy Metabolism; Humans; Hypoxanthine; Hypoxanthines; Intermittent Claudication; Ischemia; Lactates; Lactic Acid; Leg; Male; Middle Aged; Muscles; Pyruvates; Pyruvic Acid | 1991 |
[Protective action of sophoridine on acute myocardial infarction in anesthetized dogs].
Topics: 6-Ketoprostaglandin F1 alpha; Alkaloids; Animals; Creatine Kinase; Dogs; Female; Lactates; Lactic Acid; Male; Matrines; Myocardial Infarction; Myocardium; Pyruvates; Pyruvic Acid; Quinolizines; Thromboxane B2 | 1991 |
Glucose utilization by sheep embryos derived in vivo and in vitro.
Topics: 2,4-Dinitrophenol; Analysis of Variance; Animals; Blastocyst; Cleavage Stage, Ovum; Dinitrophenols; Drug Interactions; Fertilization in Vitro; Fetus; Glucose; Glycolysis; Lactates; Lactic Acid; Morula; Pyruvates; Pyruvic Acid; Sheep | 1991 |
Glutamine and glucose metabolism in thymocytes from normal and spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Animals; Cell Count; Diabetes Mellitus, Experimental; Female; Glucose; Glutamine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred BB; T-Lymphocytes | 1991 |
A new ergopeptide, CBM 36-733, improves ischaemic cerebral metabolism in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Ergolines; Female; Hemodynamics; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred SHR | 1991 |
The effect of fructose on alcohol metabolism and on the [lactate]/[pyruvate] ratio in man.
Topics: Adolescent; Adult; Alcohol Drinking; Ethanol; Fructose; Humans; Lactates; Lactic Acid; Male; Metabolic Clearance Rate; Middle Aged; Pyruvates; Pyruvic Acid; Reference Values | 1991 |
Regulation of glycolysis in the erythrocyte: role of the lactate/pyruvate and NAD/NADH ratios.
Topics: Adult; Erythrocytes; Glycolysis; Humans; Lactates; Lactic Acid; NAD; Pyruvates; Pyruvic Acid | 1991 |
Optical measurement of perfused rat hindlimb muscle with relation of the oxygen metabolism.
Topics: Animals; Cyanides; Cytochromes; Kinetics; Lactates; Lactic Acid; Male; Muscles; Myoglobin; Oxidation-Reduction; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Spectrophotometry; Temperature | 1991 |
Effect of exogenous fructose-1,6-bisphosphate on glycolysis in the isolated perfused rat heart.
Topics: Animals; Female; Fructose; Fructosediphosphates; Glycogen; Glycolysis; Heart; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
The possible metabolic diversions adapted by the cockroach, Periplaneta americana to counteract the toxicity of fenvalerate.
Topics: Adaptation, Physiological; Administration, Topical; Amino Acids; Animals; Aspartate Aminotransferases; Central Nervous System; Glycogen; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Malate Dehydrogenase; Nitriles; Periplaneta; Proteins; Pyrethrins; Pyruvates; Pyruvic Acid; Succinate Dehydrogenase; Time Factors | 1991 |
The cytotoxicity of p-chloro-m-xylenol in primary culture of rat hepatocytes.
Topics: Animals; Cell Survival; Cells, Cultured; Disinfectants; Drug Evaluation, Preclinical; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Rats; Xylenes | 1991 |
Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children: effect of dichloroacetate and glucose infusion.
Topics: Absorption; Adult; Alanine; Burns; Carbon Isotopes; Child; Child, Preschool; Dichloroacetic Acid; Energy Metabolism; Glucose; Humans; Infusions, Intravenous; Lactates; Lactic Acid; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Reference Values | 1991 |
[Study of the status of energy metabolism in thyrotoxicosis by the insulin test].
Topics: Adult; Blood Glucose; Catecholamines; Energy Metabolism; Female; Glycolysis; Humans; Insulin; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Thyrotoxicosis | 1991 |
Effect of lactation on gluconeogenesis and ketogenesis in ovine hepatocytes.
Topics: Animals; Butyrates; Butyric Acid; Carnitine; Female; Gluconeogenesis; Ketone Bodies; Kinetics; Lactates; Lactation; Lactic Acid; Liver; Palmitic Acid; Palmitic Acids; Propionates; Pyruvates; Pyruvic Acid; Sheep | 1991 |
Energy substrate requirements for in-vitro development of hamster 1- and 2-cell embryos to the blastocyst stage.
Topics: Amino Acids; Animals; Blastocyst; Cleavage Stage, Ovum; Cricetinae; Culture Media; Culture Techniques; Dose-Response Relationship, Drug; Energy Metabolism; Glutamine; Lactates; Lactic Acid; Morula; Pyruvates; Pyruvic Acid | 1991 |
Marked reduction in CSF lactate and pyruvate levels after CoQ therapy in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS).
Topics: Acidosis, Lactic; Adult; Agnosia; Cerebrovascular Disorders; Delirium; Dose-Response Relationship, Drug; Hemianopsia; Humans; Lactates; Lactic Acid; Magnetic Resonance Imaging; Male; Mitochondria, Muscle; Neurologic Examination; Neuromuscular Diseases; Pyruvates; Pyruvic Acid; Syndrome; Ubiquinone | 1991 |
Substrate and pH effects on glutamine synthesis in rat liver. Consequences for acid-base regulation.
Topics: Acid-Base Equilibrium; Ammonia; Ammonium Chloride; Animals; Glucose; Glutamine; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Male; Nitrogen; Ornithine; Portal Vein; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
Secretory and metabolic effects of ethanol in the isolated amphibian gastric mucosa.
Topics: Alcohol Dehydrogenase; Alcoholic Beverages; Animals; Anti-Ulcer Agents; Beer; Bufo marinus; Cimetidine; Ethanol; Gastric Acid; Gastric Mucosa; Imidazoles; In Vitro Techniques; Lactates; Lactic Acid; Oxygen Consumption; Pyruvates; Pyruvic Acid; Secretory Rate; Wine | 1991 |
[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus].
Topics: 2,3-Diphosphoglycerate; Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Coma; Diabetic Ketoacidosis; Diagnosis, Differential; Diphosphoglyceric Acids; Erythrocytes; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1991 |
Interstitial and cerebrospinal fluid levels of energy-related metabolites after middle cerebral artery occlusion in rats.
Topics: Animals; Arterial Occlusive Diseases; Brain Ischemia; Cerebral Arteries; Energy Metabolism; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
Vasopressin stimulates pyruvate utilization through a Ca(2+)-dependent mechanism and lactate formation by a protein kinase C-dependent mechanism in isolated rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Coumaric Acids; Epidermal Growth Factor; Fatty Acids; Glucose; Lactates; Lactic Acid; Liver; Protein Kinase C; Pyruvates; Pyruvic Acid; Rats; Type C Phospholipases; Vasopressins | 1991 |
Thermogenesis of white adipocytes: a novel method allowing long-term microcalorimetric investigations.
Topics: Adipose Tissue; Animals; Body Temperature Regulation; Calorimetry; Glucose; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Tissue metabolite levels in different types of skeletal muscle during sepsis.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Energy Metabolism; Hindlimb; Humans; Infections; Lactates; Lactic Acid; Male; Muscles; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Toes | 1991 |
Therapeutic effect of sodium dichloroacetate on visual and auditory hallucinations in a patient with MELAS.
Topics: Acidosis, Lactic; Administration, Oral; Adult; Auditory Perception; Dichloroacetic Acid; Hallucinations; Humans; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Neurocognitive Disorders; Neuromuscular Diseases; Pyruvates; Pyruvic Acid; Syndrome; Visual Perception | 1991 |
Glucose and phosphate inhibit respiration and oxidative metabolism in cultured hamster eight-cell embryos: evidence for the "crabtree effect".
Topics: Aerobiosis; Anaerobiosis; Animals; Citric Acid Cycle; Cricetinae; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Female; Glucose; Hydrogen Peroxide; Lactates; Lactic Acid; Mesocricetus; Oxygen Consumption; Phosphates; Pyruvates; Pyruvic Acid | 1991 |
Seasonal cyclicity in carbohydrate metabolism parameters in the European bison, Bison bonasus L.
Topics: Alkalies; Animals; Artiodactyla; Blood Glucose; Carbohydrate Metabolism; Female; Lactates; Lactic Acid; Lipids; Male; Pyruvates; Pyruvic Acid; Seasons; Sex Factors | 1990 |
Repartitioning effect of a mixed beta-agonist on body composition.
Topics: Adrenergic beta-Agonists; Animals; Blood Glucose; Body Composition; Body Weight; Carboxypeptidases; Cathepsin A; Cathepsins; Eating; Growth; Lactates; Lactic Acid; Male; Metaproterenol; Muscles; Oxidation-Reduction; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Kinetic mechanism of the endogenous lactate dehydrogenase activity of duck epsilon-crystallin.
Topics: Animals; Binding, Competitive; Coenzymes; Crystallins; Ducks; Heart; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Myocardium; NAD; Oxamic Acid; Pyruvates; Pyruvic Acid; Substrate Specificity; Tartronates | 1991 |
L-lactate uptake by rat liver. Effect of food deprivation and substrate availability.
Topics: Animals; Female; Food Deprivation; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Substrate Specificity | 1991 |
Myocardial uptake of amino acids and other substrates in relation to myocardial oxygen consumption four hours after cardiac operations.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Amino Acids; Blood Glucose; Coronary Artery Bypass; Fatty Acids, Nonesterified; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Male; Middle Aged; Myocardium; Oxygen Consumption; Pyruvates; Pyruvic Acid; Time Factors | 1991 |
Stimulation of alanine metabolism by ammonia in the perfused rat liver. Quantitative analysis by means of a mathematical model.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Ammonium Chloride; Animals; Caprylates; Energy Metabolism; Female; Gluconeogenesis; Glucose; Hydroxybutyrates; Kinetics; Lactates; Lactic Acid; Liver; Mathematics; Models, Biological; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1991 |
The short-term effect of nicotinic acid on intermediary metabolism in insulin-dependent diabetes mellitus.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Humans; Insulin; Ketone Bodies; Lactates; Lactic Acid; Male; Niacin; Pyruvates; Pyruvic Acid; Triglycerides | 1991 |
Maximal activity of phosphate-dependent glutaminase and glutamine metabolism in septic rats.
Topics: Alanine; Animals; Arteries; Glutaminase; Glutamine; Intestinal Mucosa; Kidney; Lactates; Lactic Acid; Liver; Lymph Nodes; Lymphocytes; Male; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sepsis; Veins | 1991 |
Mitochondrial myopathy in Marinesco-Sjögren syndrome.
Topics: Adolescent; Adult; Biopsy; Cerebellum; Chromosome Aberrations; Chromosome Disorders; Exercise Test; Female; Genes, Recessive; Humans; Lactates; Lactic Acid; Male; Microscopy, Electron; Mitochondria, Muscle; Muscle Hypotonia; Muscles; Neurologic Examination; Neuromuscular Diseases; Pyruvates; Pyruvic Acid; Spinocerebellar Degenerations; Tomography, X-Ray Computed | 1991 |
Lactate dehydrogenase from gastrocnemius muscle of turtle.
Topics: Animals; Chromatography, Affinity; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Muscles; NAD; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid; Substrate Specificity; Temperature; Turtles | 1990 |
Glucose and lactate in human follicular fluid: concentrations and interrelationships.
Topics: Clomiphene; Estradiol; Female; Follicular Fluid; Glucose; Glycolysis; Granulosa Cells; Humans; Lactates; Lactic Acid; Models, Biological; Progesterone; Pyruvates; Pyruvic Acid; Theca Cells | 1990 |
Detection of non-volatile organic acids by head-space gas chromatography.
Topics: Bacteroides fragilis; Carboxylic Acids; Chromatography, Gas; Fumarates; Lactates; Lactic Acid; Malonates; Methylmalonic Acid; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid | 1990 |
Prostaglandin F2 alpha stimulates gluconeogenesis in the perfused rat liver and this effect is blunted in livers from endotoxin infused rats.
Topics: Animals; Dinoprost; Endotoxins; Escherichia coli; Gluconeogenesis; Kinetics; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Diurnal pattern of plasma metformin concentrations and its relation to metabolic effects in type 2 (non-insulin-dependent) diabetic patients.
Topics: Alanine; Blood Glucose; Butyrates; Butyric Acid; Circadian Rhythm; Diabetes Mellitus, Type 2; Glycerol; Humans; Lactates; Lactic Acid; Metformin; Pyruvates; Pyruvic Acid | 1990 |
Acute toxic effect of sodium dichromate on metabolism.
Topics: Amino Acids; Animals; Chromates; Chromium; Cyanosis; Glucose Tolerance Test; Lactates; Lactic Acid; Liver Glycogen; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sodium Compounds | 1990 |
[Behavior of various enzyme activities during high blood lactate and pyruvate levels in albino rats reared in a normobaric hypoxic atmosphere for 1 or 2 generations].
Topics: Acid-Base Equilibrium; Adaptation, Physiological; Animals; Atmosphere Exposure Chambers; Creatine Kinase; Glutamate Dehydrogenase; Hypoxia; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Effect of lactate and beta-hydroxybutyrate infusions on brain metabolism in the fetal sheep.
Topics: 3-Hydroxybutyric Acid; Animals; Blood-Brain Barrier; Brain; Cerebrovascular Circulation; Female; Fetus; Glucose; Hydrogen-Ion Concentration; Hydroxybutyrates; Lactates; Lactic Acid; Oxygen; Pregnancy; Pyruvates; Pyruvic Acid; Sheep | 1990 |
Hyperglycemic effect of prolactin in anterior pituitary transplanted rats.
Topics: Animals; Female; Hyperglycemia; Lactates; Lactic Acid; Pituitary Gland; Pituitary Gland, Anterior; Prolactin; Pyruvates; Pyruvic Acid; Radioimmunoassay; Rats; Rats, Inbred Strains | 1990 |
[Changes in the glycolytic pathway in patients with essential arterial hypertension].
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Diphosphoglyceric Acids; Glycolysis; Humans; Hypertension; Lactates; Lactic Acid; Middle Aged; Pyruvates; Pyruvic Acid | 1990 |
Sodium D-lactate infusion of panic disorder patients.
Topics: Adult; Agoraphobia; Bicarbonates; Blood Pressure; Calcium; Carbon Dioxide; Fear; Female; Heart Rate; Humans; Hyperventilation; Infusions, Intravenous; Lactates; Lactic Acid; Male; Panic; Phobic Disorders; Phosphates; Pilot Projects; Pyruvates; Pyruvic Acid; Stereoisomerism | 1990 |
Menadione partially restores NADH-oxidation and ATP-synthesis in complex I deficient fibroblasts.
Topics: Adenosine Triphosphate; Cells, Cultured; Fibroblasts; Glucose; Humans; Lactates; Lactic Acid; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pyruvates; Pyruvic Acid; Quinone Reductases; Rotenone; Vitamin K | 1990 |
Stimulation of rat red blood cell glycolysis by phenylhydrazine hydrochloride.
Topics: Adenine Nucleotides; Animals; Calcium; Calcium-Transporting ATPases; Erythrocytes; Glycolysis; Lactates; Lactic Acid; Pentose Phosphate Pathway; Phenylhydrazines; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
[Changes in ketone body ratio and levels of pyruvate and lactate in arterial blood of patients with hepatocellular carcinoma after transcatheter arterial embolization].
Topics: Carcinoma, Hepatocellular; Embolization, Therapeutic; Humans; Ketones; Lactates; Lactic Acid; Liver; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Pyruvates; Pyruvic Acid | 1990 |
Effect of mitochondrial inhibitors on adenosinetriphosphate levels in Plasmodium falciparum.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dicyclohexylcarbodiimide; Electron Transport Complex III; Kinetics; Lactates; Lactic Acid; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Oligomycins; Plasmodium falciparum; Potassium Cyanide; Pyruvates; Pyruvic Acid; Quinone Reductases; Rotenone | 1990 |
Detection of respiratory chain dysfunction by measuring lactate and pyruvate production in cultured fibroblasts.
Topics: Amino Acid Metabolism, Inborn Errors; Cells, Cultured; Child, Preschool; Cytochrome-c Oxidase Deficiency; Fibroblasts; Humans; Infant, Newborn; Lactates; Lactic Acid; Mitochondria; Oxygen Consumption; Pyruvates; Pyruvic Acid; Quinone Reductases | 1990 |
The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lacticacidemia.
Topics: Acidosis, Lactic; Brain Diseases; Cells, Cultured; Cytochrome-c Oxidase Deficiency; Fibroblasts; Humans; Infant; Infant, Newborn; Lactates; Lactic Acid; Metabolism, Inborn Errors; Oxygen Consumption; Pyruvates; Pyruvic Acid; Skin | 1990 |
Development and regulation of hepatocellular fatty acid synthesis towards term: studies in isolated fetal rat hepatocytes.
Topics: Animals; Caprylates; Cyclic AMP; Fatty Acids; Female; Insulin; Lactates; Lactic Acid; Liver; NAD; NADP; Pregnancy; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Regulation of glycogen synthesis from glucose and gluconeogenic precursors by insulin in periportal and perivenous rat hepatocytes.
Topics: Animals; Cells, Cultured; Fasting; Food; Gluconeogenesis; Glucose; Glycogen; Insulin; Kinetics; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
The protective action of pyruvate on recovery of ischemic rat heart: comparison with other oxidizable substrates.
Topics: Acetates; Animals; Coronary Disease; Energy Metabolism; Glucose; Heart; Insulin; Lactates; Lactic Acid; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1990 |
Gut exchange of glucose and lactate in basal state and after oral glucose ingestion in postoperative patients.
Topics: 3-Hydroxybutyric Acid; Absorption; Administration, Oral; Amino Acids; Arteries; Blood Glucose; Catecholamines; Female; Gluconeogenesis; Glucose; Glycerol; Humans; Hydroxybutyrates; Insulin; Intestinal Mucosa; Lactates; Lactic Acid; Male; Osmolar Concentration; Portal Vein; Postoperative Period; Pyruvates; Pyruvic Acid | 1990 |
Effect of insulin on glucose utilization in epitrochlearis muscle of rats with streptozocin-induced NIDDM.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glucosephosphates; Glycogen; Humerus; Insulin; Insulin Resistance; Lactates; Lactic Acid; Muscles; Organ Size; Phosphocreatine; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
[Experimental study on pathogenesis of neonatal hypoxic-ischemic encephalopathy. II. Energy metabolism in the brain].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Hypoxia, Brain; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Follow-up of the long-term effect of intraarterial vasodilator administration in patients with PAOD by means of changes in resting arterial and venous lactate and pyruvate levels, and in ABB parameters.
Topics: Acid-Base Equilibrium; Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Female; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Ischemia; Lactates; Lactic Acid; Leg; Male; Middle Aged; Pyruvates; Pyruvic Acid; Vasodilator Agents | 1990 |
On the mechanism of sodium 2-5-4 chlorophenylpentyloxirane-2-carboxylate (POCA) inhibition of hepatic gluconeogenesis.
Topics: Animals; Dose-Response Relationship, Drug; Epoxy Compounds; Fatty Acids; Gluconeogenesis; Glucose; Lactates; Lactic Acid; Liver; Male; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation | 1990 |
Elevation of blood lactate and pyruvate levels in acute intermittent porphyria--a reflection of haem deficiency?
Topics: Adult; Blood Glucose; Female; Glucose; Heme; Humans; Lactates; Lactic Acid; Male; Porphyrias; Pyruvates; Pyruvic Acid | 1990 |
The in vitro effects of four isomers of dinitrotoluene on rat Sertoli and Sertoli-germ cell cocultures: germ cell detachment and lactate and pyruvate production.
Topics: Animals; Cell Adhesion; Cells, Cultured; Dinitrobenzenes; Germ Cells; Isomerism; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sertoli Cells; Testis | 1990 |
Differential incorporation of gluconeogenic precursors and glucose into glycogen in periportal and perivenous rat hepatocytes.
Topics: Animals; Gluconeogenesis; Glucose; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Kinetic asymmetry of renal Na+-L-lactate cotransport. Characteristic parameters and evidence for a ping pong mechanism of the trans-stimulating exchange by pyruvate.
Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Horses; Kidney; Kinetics; Lactates; Lactic Acid; Microvilli; Monocarboxylic Acid Transporters; Pyruvates; Pyruvic Acid; Sodium; Symporters | 1990 |
Metabolic oxidation of pyruvate and lactate during early myocardial reperfusion.
Topics: Animals; Coronary Disease; Fatty Acids; Heart; Lactates; Lactic Acid; Myocardial Reperfusion; Myocardium; Oxidation-Reduction; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Swine | 1990 |
A new method to monitor Kupffer-cell function continuously in the perfused rat liver. Dissociation of glycogenolysis from particle phagocytosis.
Topics: Animals; Carbon; Colloids; Female; Glucose; Glycogen; Kupffer Cells; Lactates; Lactic Acid; Liver; Microscopy, Electron, Scanning; Oxygen Consumption; Perfusion; Phagocytosis; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Toxicity of the pyrethroid insecticide fenvalerate to a fresh water fish, Tilapia mossambica (Peters): changes in glycogen metabolism of muscle.
Topics: Animals; Fishes; Fructose-Bisphosphate Aldolase; Glycogen; Insecticides; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Malate Dehydrogenase; Muscles; Nitriles; Oxygen Consumption; Phosphorylases; Pyrethrins; Pyruvates; Pyruvic Acid; Succinate Dehydrogenase | 1990 |
Concentrations of nutrients in mouse oviduct fluid and their effects on embryo development and metabolism in vitro.
Topics: Animals; Body Fluids; Culture Media; Embryo, Mammalian; Embryonic and Fetal Development; Fallopian Tubes; Female; Fluorometry; Glucose; Lactates; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pregnancy; Pyruvates; Pyruvic Acid | 1990 |
[Experimental study of the viability of warm ischemic kidney. Relationship between ATP value in renal tissue by isotachophoresis and serum pyruvic acid to lactic acid ratio (P/L ratio)].
Topics: Adenosine Triphosphate; Animals; Electrophoresis; Ischemia; Kidney; Lactates; Lactic Acid; Mitochondria; Pyruvates; Pyruvic Acid; Rabbits; Temperature; Tissue Preservation; Tissue Survival | 1990 |
Muscle carnitine metabolism during incremental dynamic exercise in humans.
Topics: Acetyl Coenzyme A; Acetylcarnitine; Adult; Carnitine; Exercise; Humans; Lactates; Lactic Acid; Male; Muscles; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1990 |
Kinetic analysis of duck epsilon-crystallin, a lens structural protein with lactate dehydrogenase activity.
Topics: Animals; Chickens; Chromatography, Ion Exchange; Crystallins; Drug Stability; Ducks; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lens, Crystalline; Muscles; Myocardium; NAD; Pyruvates; Pyruvic Acid | 1990 |
[Effects of various oxygen concentrations on metabolic performance of in vitro perfused human placentas].
Topics: Blood Glucose; Cell Hypoxia; Energy Metabolism; Female; Glycolysis; Humans; Lactates; Lactic Acid; Oxygen Consumption; Perfusion; Placenta; Pregnancy; Pyruvates; Pyruvic Acid | 1990 |
[Biochemical effects of discontinuous muscle work in arterial occlusive disease].
Topics: Arterial Occlusive Diseases; Exercise Test; Humans; Ischemia; Lactates; Lactic Acid; Leg; Male; Middle Aged; Muscle Contraction; Pyruvates; Pyruvic Acid | 1990 |
Respiratory failure and stimulation of glycolysis in Chinese hamster ovary cells exposed to normobaric hyperoxia.
Topics: Adenosine Triphosphate; Amino Acids; Ammonia; Animals; Cell Division; Cell Line; Cell Membrane Permeability; Citric Acid Cycle; Cricetinae; Digitonin; Dinitrophenols; Female; Glucose; Glucosephosphate Dehydrogenase; Glutathione Reductase; Glycolysis; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Spectrophotometry | 1990 |
Carbohydrate utilization in exercising muscle in subtotally nephrectomized rabbits.
Topics: Alanine; Animals; Carbohydrate Metabolism; Glutamine; Glycogen; Ketoglutaric Acids; Kidney; Kidney Failure, Chronic; Lactates; Lactic Acid; Muscles; Nephrectomy; Physical Exertion; Pyruvates; Pyruvic Acid; Rabbits | 1990 |
Shock, transfusion, and pneumonectomy. Death is due to right heart failure and increased pulmonary vascular resistance.
Topics: Animals; Blood Pressure; Blood Transfusion; Cardiac Output; Cardiac Output, Low; Heart; Lactates; Lactic Acid; Lung Injury; Pneumonectomy; Pulmonary Artery; Pulmonary Circulation; Pyruvates; Pyruvic Acid; Resuscitation; Shock, Hemorrhagic; Swine; Vascular Resistance | 1990 |
Influence of colloidal carbon phagocytosis as a metabolic load on the hepatic energy metabolism in rats.
Topics: Adenine Nucleotides; Animals; Carbon; Colloids; Energy Metabolism; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Phagocytosis; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1990 |
Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats.
Topics: Adenosine; Amino Acids; Animals; Body Temperature; Brain Concussion; Cerebral Cortex; Chromatography, High Pressure Liquid; Energy Metabolism; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats | 1990 |
Relation between myocardial substrate utilization, oxygen consumption and regional oxygen balance in the dog heart in vivo.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Dogs; Fatty Acids, Nonesterified; Female; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1986 |
Acute and chronic effects of insulin on lactate dehydrogenase (LDH) activity in tissues of albino rat (Wistar strain).
Topics: Animals; Hyperinsulinism; Insulin; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
Absence of lactate accumulation on transurethral resection of the prostate using 2.5% sorbitol solution as an irrigating fluid.
Topics: Blood Glucose; Fructose; Humans; Lactates; Lactic Acid; Male; Phosphates; Postoperative Complications; Prostatectomy; Prostatic Hyperplasia; Pyruvates; Pyruvic Acid; Sorbitol; Therapeutic Irrigation; Urethra | 1988 |
Metabolic response to short term starvation in non-pregnant and late pregnant cafeteria-obese rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Female; Fetal Blood; Glycerol; Hydroxybutyrates; Lactates; Lactic Acid; Obesity; Pregnancy; Pregnancy Complications; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Urea | 1989 |
Blood carbohydrates and phosalone poisoning in Rana tigrina (Daudin).
Topics: Animals; Body Weight; Carbohydrates; Female; Lactates; Lactic Acid; Male; Organophosphorus Compounds; Organothiophosphorus Compounds; Pyruvates; Pyruvic Acid; Ranidae | 1989 |
Comparison of different flow injection approaches to the automatic determination of enzymatic activity.
Topics: Enzymes; Hydrogen-Ion Concentration; Indicators and Reagents; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Pyruvates; Pyruvic Acid; Spectrophotometry, Ultraviolet; Temperature | 1989 |
Brain acidosis in experimental pneumococcal meningitis.
Topics: Acidosis; Animals; Blood Glucose; Brain Diseases; Carbon Dioxide; Glucose; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Leukocytes; Meningitis, Pneumococcal; Mice; Pyruvates; Pyruvic Acid; Rabbits | 1989 |
Alpha hydroxy acids: procedures for use in clinical practice.
Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Ichthyosis; Keratosis; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Skin Diseases; Warts | 1989 |
Behavioral biochemical and neuroendocrine concomitants of lactate-induced panic anxiety.
Topics: Adult; Anxiety Disorders; Arousal; beta-Endorphin; Bicarbonates; Fear; Female; Heart Rate; Humans; Infusions, Intravenous; Lactates; Lactic Acid; Male; Methoxyhydroxyphenylglycol; Panic; Pyruvates; Pyruvic Acid | 1989 |
Metabolic effects of acetate on the heart.
Topics: Acetates; Acetic Acid; Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Coronary Circulation; Dipyridamole; Glucose; Heart; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1989 |
Metabolic profiles in patients with insulinoma.
Topics: Adenoma, Islet Cell; Adult; Aged; Alanine; Blood Glucose; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Insulin; Insulinoma; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pancreatic Neoplasms; Pyruvates; Pyruvic Acid | 1989 |
End products of glutamine oxidation in MC-29 virus-induced chicken hepatoma mitochondria.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Citric Acid Cycle; Glutamates; Glutamic Acid; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Stimulation of glutamine metabolism by the antiepileptic drug, sodium valproate, in isolated dog kidney tubules.
Topics: Alanine; Ammonia; Animals; Aspartic Acid; Dogs; Female; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Kidney Tubules; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Valproic Acid | 1989 |
[Biotinidase deficiency: a congenital metabolic disease which can be successfully treatment with vitamin H].
Topics: Acid-Base Equilibrium; Administration, Oral; Amidohydrolases; Biotin; Biotinidase; Follow-Up Studies; Humans; Infant; Lactates; Lactic Acid; Male; Multiple Carboxylase Deficiency; Pyruvates; Pyruvic Acid | 1989 |
[Comparison of effects on carbohydrate metabolism of hypotension induced by sodium nitroprusside and a nitroprusside-trimetaphan mixture in rabbits].
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Drug Combinations; Ferricyanides; Hypotension, Controlled; Lactates; Lactic Acid; Nitroprusside; Pyruvates; Pyruvic Acid; Rabbits; Trimethaphan | 1989 |
The relationship of plasma acetate with glucose and other blood intermediary metabolites in non-diabetic and diabetic subjects.
Topics: Acetates; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Humans; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
Whole body and regional fuel metabolism during early postexercise recovery.
Topics: Adult; Alanine; Amino Acids, Branched-Chain; Blood Glucose; Calorimetry, Indirect; Energy Metabolism; Exercise; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Humans; Insulin; Lactates; Lactic Acid; Lipid Metabolism; Male; Muscles; Norepinephrine; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1989 |
alpha-Glycerophosphate shuttle in a clonal beta-cell line.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amobarbital; Cell Line; Clone Cells; Cytosol; Electron Transport; Glucose; Glycerolphosphate Dehydrogenase; Glycerophosphates; Glycolysis; Guanosine Diphosphate; Guanosine Triphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1989 |
Differential effects of insulin and hyperglycemia on intracellular glucose disposition in humans.
Topics: Adult; Female; Glucose; Humans; Hyperglycemia; Insulin; Intracellular Membranes; Lactates; Lactic Acid; Male; Oxidation-Reduction; Proteins; Pyruvates; Pyruvic Acid | 1989 |
Metabolic effects of three ketogenic diets in the treatment of severe epilepsy.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Dietary Fats; Energy Metabolism; Epilepsy; Glycerol; Humans; Insulin; Ketone Bodies; Lactates; Lactic Acid; Middle Aged; Pyruvates; Pyruvic Acid; Triglycerides; Uric Acid | 1989 |
Lactate dehydrogenase displays absolute stereospecificity in the transfer of the prochiral hydrogen of NADH.
Topics: Animals; Deuterium; Hydrogen; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Myocardium; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Radioisotope Dilution Technique; Stereoisomerism; Swine; Tritium | 1989 |
Persistent abnormalities of the metabolism of an oral glucose load in insulin-treated type I diabetics.
Topics: Administration, Oral; Alanine; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 1; Forearm; Glucose; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1989 |
Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver.
Topics: Animals; Caprylates; Carbohydrate Metabolism; Electric Stimulation; Fatty Acids; Glucagon; Glucose; Insulin; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1989 |
Effects of substrate and hypoxia on smooth muscle metabolism and contraction.
Topics: Anaerobiosis; Animals; Energy Metabolism; Female; Glucose; Lactates; Lactic Acid; Muscle Contraction; Muscle, Smooth; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rabbits; Urinary Bladder | 1989 |
Effects of propylene glycol on redox state of the perfused rat liver--a note of caution.
Topics: 3-Hydroxybutyric Acid; Animals; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Perfusion; Propylene Glycol; Propylene Glycols; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1989 |
[Enzymes and metabolic products in the cerebrospinal fluid in acute craniocerebral trauma].
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Brain Injuries; Cerebrospinal Fluid; Clinical Enzyme Tests; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1989 |
[The role of ascorbic acid in the combined preoperative preparation of cancer patients].
Topics: Administration, Oral; Ascorbic Acid; Ascorbic Acid Deficiency; Combined Modality Therapy; Esophageal Neoplasms; Humans; Infusions, Intravenous; Lactates; Lactic Acid; Lung Neoplasms; Oxidation-Reduction; Preoperative Care; Pyruvates; Pyruvic Acid; Stomach Neoplasms | 1989 |
A further study of human seminal plasma lactate dehydrogenase-C4 (LDH-C4): kinetic properties of LDH-C4.
Topics: Hemiterpenes; Humans; Keto Acids; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Semen; Spermatozoa | 1989 |
[The action of cyclosporin A (CSA) on glycogen synthesis processes in rats in vivo].
Topics: Animals; Blood Glucose; Cyclosporins; Fasting; Glycogen; Heart; Lactates; Lactic Acid; Liver Glycogen; Male; Muscles; Myocardium; Pyruvates; Pyruvic Acid; Rats; Time Factors | 1989 |
Calcium uptake by bovine epididymal spermatozoa is regulated by the redox state of the mitochondrial pyridine nucleotides.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Ascorbic Acid; Butyrates; Butyric Acid; Calcium; Caproates; Cattle; Digitonin; Epididymis; Hydroxybutyrates; Lactates; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Pentanoic Acids; Pyruvates; Pyruvic Acid; Rotenone; Spermatozoa; Tetramethylphenylenediamine | 1989 |
Effect of diet on [lactate]/[pyruvate] ratios during alcohol metabolism in man.
Topics: Adult; Alcoholic Intoxication; Dietary Carbohydrates; Dietary Fats; Ethanol; Humans; Lactates; Lactic Acid; Male; Metabolic Clearance Rate; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
Effects of hyperthermia on the peripheral metabolism of ammonia and glutamine.
Topics: Acid-Base Equilibrium; Alanine; Ammonia; Arteries; Blood Glucose; Body Temperature; Fatty Acids, Nonesterified; Female; Fever; Forearm; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
A protocol for the routine measurement of lactate and pyruvate in cord blood.
Topics: Blood Specimen Collection; Female; Fetal Blood; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Time Factors | 1989 |
Effects of hyperventilation, hypothermia, and altered blood viscosity on cerebral blood flow, cross-brain oxygen extraction, and cerebral metabolic rate for oxygen in cats.
Topics: Animals; Blood Viscosity; Brain Injuries; Cats; Cerebrovascular Circulation; Hyperventilation; Hypothermia, Induced; Lactates; Lactic Acid; Oxygen; Pyruvates; Pyruvic Acid | 1989 |
The characterization of perfluorosuccinate as an inhibitor of gluconeogenesis in isolated rat hepatocytes.
Topics: Animals; Antimetabolites; Aspartate Aminotransferases; Ethanol; Fluorocarbons; Gluconeogenesis; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Malates; Male; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinates; Succinic Acid | 1989 |
Training increases cardiac glucose uptake during rest and exercise in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Deoxyglucose; Fatty Acids, Nonesterified; Glucose; Heart Rate; Lactates; Lactic Acid; Male; Myocardium; Physical Conditioning, Animal; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Rest; Tissue Distribution | 1989 |
Cerebral effects of anaesthesia and hypothermia.
Topics: Adult; Anesthesia; Brain; Cardiopulmonary Bypass; Cerebrovascular Circulation; Coronary Artery Bypass; Fentanyl; Glucose; Hemodynamics; Humans; Hypothermia, Induced; Lactates; Lactic Acid; Male; Midazolam; Middle Aged; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1989 |
Kinetics of oral propylene glycol-induced acute hyperlactatemia.
Topics: Alcohol Dehydrogenase; Animals; Blood Glucose; Kinetics; Lactates; Lactic Acid; Male; Propylene Glycol; Propylene Glycols; Pyrazoles; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1989 |
Assessment of muscular metabolism in peripheral arterial occlusive disease using 31P nuclear magnetic resonance spectroscopy. Comparison with metabolite concentrations in femoral blood.
Topics: Acid-Base Equilibrium; Adenosine Triphosphate; Adult; Arterial Occlusive Diseases; Exercise Test; Glycolysis; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Muscles; Phosphates; Phosphocreatine; Purine Nucleotides; Pyruvates; Pyruvic Acid | 1989 |
Lactate and pyruvate kinetics after treadmill exercise in patients with intermittent claudication.
Topics: Adult; Aged; Exercise Test; Humans; Intermittent Claudication; Kinetics; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
[Interval exercise in arterial occlusive disease].
Topics: Energy Metabolism; Exercise Test; Humans; Intermittent Claudication; Lactates; Lactic Acid; Male; Middle Aged; Muscles; Pyruvates; Pyruvic Acid | 1989 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Energy value of glucose and lactate for the myocardium in patients with mitral stenosis.
Topics: Adenine Nucleotides; Energy Metabolism; Glucose; Humans; In Vitro Techniques; Lactates; Lactic Acid; Mitral Valve Stenosis; Myocardium; Pyruvates; Pyruvic Acid | 1989 |
[Lactate and pyruvate blood levels in the diagnosis of mitochondrial myopathies].
Topics: Adolescent; Adult; Aged; Exercise Test; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria, Muscle; Neuromuscular Diseases; Pyruvates; Pyruvic Acid | 1989 |
Lactate and pyruvate increase the incorporation of [3H]proline into collagen [3H]hydroxyproline in liver slices of CCl4 cirrhotic rats.
Topics: Animals; Carbon Tetrachloride; Collagen; Cyclic AMP; Hydroxyproline; Lactates; Lactic Acid; Liver; Liver Cirrhosis, Experimental; Male; Proline; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
The mechanism by which adenosine decreases gluconeogenesis from lactate in isolated rat hepatocytes.
Topics: Adenine Nucleotides; Adenosine; Alanine; Animals; Cyclic AMP; Gluconeogenesis; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Liver; Phosphates; Pyruvates; Pyruvic Acid; Rats | 1987 |
Regulation of lactate/pyruvate ratios by cyclic AMP in Neurospora crassa.
Topics: Adenylyl Cyclases; Chromatography, High Pressure Liquid; Cyclic AMP; Glycolysis; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mutation; NAD; Neurospora; Neurospora crassa; Pyruvates; Pyruvic Acid | 1988 |
[A case of mitochondrial encephalomyopathy with myoclonic attacks, hyper-lactic-pyruvic acidemia, and decreased activities of complex II and cytochrome c oxidase].
Topics: Adult; Brain Diseases, Metabolic; Electron Transport Complex II; Electron Transport Complex IV; Humans; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Multienzyme Complexes; Myoclonus; Neuromuscular Diseases; Oxidoreductases; Pyruvates; Pyruvic Acid; Succinate Dehydrogenase | 1988 |
A proton gradient is the driving force for uphill transport of lactate in human placental brush-border membrane vesicles.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anions; Biological Transport; Carboxylic Acids; Female; Furosemide; Humans; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Membrane Potentials; Microvilli; Nigericin; Placenta; Potassium; Pregnancy; Protons; Pyruvates; Pyruvic Acid; Sodium; Succinates; Succinic Acid; Valinomycin | 1988 |
Metabolic events mediating early killing of host cells infected by Shigella flexneri.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Cell Line; Cell Survival; Cyclic AMP; Energy Metabolism; Kinetics; Lactates; Lactic Acid; Macrophages; Plasmids; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Shigella flexneri; Virulence | 1987 |
Ammonia intoxication: effects on cerebral cortex and spinal cord.
Topics: Acetates; Ammonia; Animals; Blood; Carbon Dioxide; Cats; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Spinal Cord | 1985 |
Exercise-induced regulation of insulin receptor affinity: role of circulating metabolites.
Topics: Adult; Blood Glucose; C-Peptide; Epinephrine; Erythrocytes; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Insulin; Ketone Bodies; Lactates; Lactic Acid; Male; Monocytes; Physical Exertion; Prostaglandins; Pyruvates; Pyruvic Acid; Receptor, Insulin; Somatostatin | 1985 |
The metabolic response of the kidney to acute sodium lactate alkalosis.
Topics: Alanine; Alanine Transaminase; Alkalosis; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Kidney; Kidney Cortex; Lactates; Lactic Acid; Liver; Muscles; Pyruvates; Pyruvic Acid | 1985 |
On the stimulation of respiration by alpha-adrenergic agonists in perfused rat liver.
Topics: Adrenergic alpha-Agonists; Animals; Atractyloside; Gluconeogenesis; Glucose; Glycolysis; Lactates; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Phenylephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1986 |
Properties of the branched-chain 2-hydroxy acid/2-oxo acid shuttle in mouse spermatozoa.
Topics: Animals; Biological Transport; Glutamates; Glutamic Acid; Hydroxy Acids; In Vitro Techniques; Keto Acids; Lactates; Lactic Acid; Leucine; Male; Mice; Mitochondria; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid; Spermatozoa; Tissue Distribution | 1986 |
Formation of hexose 6-phosphates from lactate + pyruvate + glutamate by a cell-free system from rat liver.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell-Free System; Cytosol; Ethanol; Gluconeogenesis; Glutamates; Glutamic Acid; Hexosephosphates; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Some physiological and biochemical indices of zinc toxicity in two freshwater fishes, Clarias lazera and Tilapia zilli.
Topics: Alkaline Phosphatase; Animals; Blood Proteins; Catfishes; Erythrocyte Count; Fishes; Glycogen; Lactates; Lactic Acid; Liver Glycogen; Muscles; Pyruvates; Pyruvic Acid; Zinc | 1987 |
Further biochemical characterization of chronic Trypanosoma brucei gambiense-Microtus montanus infection.
Topics: Alkaline Phosphatase; Animals; Arvicolinae; Aspartate Aminotransferases; Blood Glucose; Ketone Bodies; Lactates; Lactic Acid; Liver; Liver Glycogen; Pyruvates; Pyruvic Acid; Trypanosoma brucei gambiense; Trypanosomiasis, African; Tyrosine Transaminase | 1987 |
Regulation of mitochondrial adenine nucleotide content in newborn rabbit liver.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine Nucleotides; Adrenergic beta-Agonists; Animals; Animals, Newborn; Bucladesine; Cytosol; Glucagon; Glucose; Hydroxybutyrates; Insulin; Isoproterenol; Kinetics; Lactates; Lactic Acid; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen; Pyruvates; Pyruvic Acid; Rabbits | 1987 |
Stimulation of anaerobic metabolism in rats at high altitude hypoxia--adrenergic effects dependent on dietary states.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Altitude Sickness; Anaerobiosis; Animals; Blood Glucose; Fasting; Food; Hypoxia; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
[Effect of physical training on the aerobic-anaerobic transition in chronic liver diseases].
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Carbon Dioxide; Fatty Acids, Nonesterified; gamma-Glutamyltransferase; Humans; Insulin; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Oxygen; Physical Exertion; Pyruvates; Pyruvic Acid | 1988 |
Effect of glycerol on gluconeogenesis in isolated rabbit kidney cortex tubules.
Topics: Acetoacetates; Animals; Gluconeogenesis; Glutamates; Glutamic Acid; Glycerol; Glycerophosphates; Ketone Bodies; Kidney Cortex; Kidney Tubules; Lactates; Lactic Acid; Male; Methylene Blue; Pyruvates; Pyruvic Acid; Rabbits | 1988 |
Energy metabolism in glutamatergic neurons, GABAergic neurons and astrocytes in primary cultures.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebellum; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Mice; Neurons; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1988 |
Pathways for organic osmolyte synthesis in rabbit renal papillary tissue, a metabolic study using 13C-labeled substrates.
Topics: Alanine; Aldehyde Reductase; Animals; Citric Acid Cycle; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Glycolysis; Inositol; Kidney Medulla; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rabbits; Sorbitol | 1988 |
Monophosphoryl lipid A blocks the hemodynamic effects of lethal endotoxemia.
Topics: Animals; Endotoxins; Hemodynamics; Lactates; Lactic Acid; Lipid A; Lipopolysaccharides; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1989 |
Cerebrospinal fluid lactate in patients with diabetes mellitus and hypoglycaemic coma.
Topics: Brain Damage, Chronic; Diabetes Mellitus; Diabetic Coma; Diabetic Neuropathies; Female; Humans; Hypoglycemia; Insulin Coma; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
Quinolinate inhibition of gluconeogenesis is dependent on cytosolic oxalacetate concentration. An explanation for the differential inhibition of lactate and pyruvate gluconeogenesis.
Topics: Animals; Asparagine; Calcium; Cytosol; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Oxaloacetates; Phosphoenolpyruvate Carboxykinase (GTP); Pyridines; Pyruvates; Pyruvic Acid; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1985 |
[Blood levels of adenine nucleotides and lactic and pyruvic acids in pregnancy].
Topics: Adenine Nucleotides; Adult; Female; Humans; Lactates; Lactic Acid; Pregnancy; Pyruvates; Pyruvic Acid; Time Factors | 1985 |
Energy metabolism and mechanical function in perfused hearts of Syrian hamsters with dilated or hypertrophic cardiomyopathy.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiomegaly; Carnitine; Coenzyme A; Coronary Circulation; Cricetinae; Diaphragm; Energy Metabolism; Glucose; Heart Failure; Heart Rate; Kidney; Lactates; Lactic Acid; Liver; Male; Mesocricetus; Palmitic Acid; Palmitic Acids; Phosphocreatine; Pyruvates; Pyruvic Acid | 1986 |
Regulation of cytotoxic T-lymphocyte activation by L-lactate and pyruvate.
Topics: Animals; Cytotoxicity, Immunologic; Lactates; Lactic Acid; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pyruvates; Pyruvic Acid; T-Lymphocytes, Cytotoxic | 1985 |
Protective effect of oxygen-derived free radical scavengers on the endothelium in vivo.
Topics: alpha-Tocopherol; Animals; Anticoagulants; Ascorbic Acid; Aspirin; Coronary Disease; Endothelium; Female; Femoral Artery; Free Radicals; Heparin; Hydrogen Peroxide; Hydroxyethylrutoside; Kinetics; Lactates; Lactic Acid; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Rutin; Tocopherols; Vitamin E | 1986 |
The coupling of metabolic to secretory events in pancreatic islets. The possible role of glutathione reductase.
Topics: Animals; Calcium; Carmustine; Cyclic AMP; Glutamine; Glutathione; Glutathione Reductase; Insulin; Islets of Langerhans; Lactates; Lactic Acid; Leucine; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1985 |
Cyclic GMP affects redox state and improves energy charge of ischaemic Langendorff-perfused rat heart.
Topics: Animals; Coronary Disease; Cyclic GMP; Energy Metabolism; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardium; NAD; Oxidation-Reduction; Perfusion; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Compartmented pyruvate in perfused working heart.
Topics: Animals; Bicarbonates; Carbon Dioxide; Carbon Radioisotopes; Cytosol; Glucose; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Myocardium; Oxidation-Reduction; Perfusion; Pyruvates; Pyruvic Acid | 1985 |
Catecholamine and vasopressin stimulation of gluconeogenesis from dihydroxyacetone in the presence of atractyloside.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atractyloside; Bucladesine; Calcium; Cytosol; Dihydroxyacetone; Fructosediphosphates; Glucagon; Gluconeogenesis; Glycosides; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; Norepinephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Trioses; Vasopressins | 1985 |
Chlorpropamide raises fructose-2,6-bisphosphate concentration and inhibits gluconeogenesis in isolated rat hepatocytes.
Topics: Animals; Chlorpropamide; Cyclic AMP; Diabetes Mellitus, Type 2; Fructosediphosphates; Gluconeogenesis; Glucose; Hexosediphosphates; Humans; Lactates; Lactic Acid; Liver; Male; Phosphofructokinase-2; Phosphotransferases; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Localization and role of pyruvate kinase isoenzymes in the regulation of carbohydrate metabolism and pyruvate recycling in rat kidney cortex.
Topics: Alanine; Animals; Bucladesine; Calcium; Carbohydrate Metabolism; Gluconeogenesis; Glucose; Immune Sera; Isoenzymes; Kidney Cortex; Lactates; Lactic Acid; Male; Parathyroid Hormone; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rabbits; Rats; Sheep | 1986 |
Respiratory chain defects in the mitochondria of cultured skin fibroblasts from three patients with lacticacidemia.
Topics: Adenosine Triphosphate; Cells, Cultured; Electron Transport Complex IV; Fibroblasts; Humans; Infant, Newborn; Lactates; Lactic Acid; Male; Mitochondria; NAD; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Oxygen Consumption; Pyruvates; Pyruvic Acid; Quinone Reductases; Skin | 1986 |
Perchloric acid interference in enzymatic-fluorimetric-continuous-flow assay methods for measuring glucose, lactate, pyruvate, alanine, glycerol, and 3-hydroxybutyrate in blood.
Topics: 3-Hydroxybutyric Acid; Alanine; Autoanalysis; Blood Glucose; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Perchlorates; Pyruvates; Pyruvic Acid | 1986 |
Effects of endogenous redox-active compounds on coupling of human beta 2-adrenergic receptors.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adolescent; Adult; Glutathione; Glutathione Disulfide; Humans; Hydrogen-Ion Concentration; Hydroxybutyrates; Isoproterenol; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Radioligand Assay; Receptors, Adrenergic, beta | 1986 |
Pyruvate dehydrogenase and the path of lactate degradation in Desulfovibrio vulgaris Miyazaki F.
Topics: Acetyl Coenzyme A; Cytochrome c Group; Desulfovibrio; Flavin Mononucleotide; Hydrogen-Ion Concentration; Ketone Oxidoreductases; Kinetics; Lactates; Lactic Acid; Molecular Weight; Pyruvate Dehydrogenase Complex; Pyruvate Synthase; Pyruvates; Pyruvic Acid; Substrate Specificity; Temperature | 1986 |
Characterization of the specific pyruvate transport system in Escherichia coli K-12.
Topics: Alanine; Biological Transport, Active; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Escherichia coli; Kinetics; Lactates; Lactic Acid; Methylphenazonium Methosulfate; Phosphotransferases; Phosphotransferases (Paired Acceptors); Pyruvates; Pyruvic Acid; Time Factors | 1987 |
[Tissue respiration in chronic bronchitis].
Topics: Adult; Bronchitis; Chronic Disease; Electron Transport Complex IV; Female; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Pyruvates; Pyruvic Acid; Sulfhydryl Compounds | 1986 |
Biochemical effects of acute stress on energy metabolism in liver damaged rats.
Topics: Acetyl Coenzyme A; Animals; Chemical and Drug Induced Liver Injury; Cyclic AMP; Cyclic GMP; Energy Metabolism; Galactosamine; Ketone Bodies; Lactates; Lactic Acid; Liver Diseases; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Stress, Physiological | 1987 |
[Metabolic indicators of early graft function in liver transplantation. Comparative study].
Topics: Animals; Bile Acids and Salts; Fibrinogen; Intraoperative Period; Lactates; Lactic Acid; Liver; Liver Function Tests; Liver Transplantation; Postoperative Period; Pyruvates; Pyruvic Acid; Swine | 1988 |
[Biochemical studies of the assessment of transplant function following clinical heart transplantation--initial experiences].
Topics: Adult; Enzymes; Female; Follow-Up Studies; Heart Function Tests; Heart Transplantation; Humans; Lactates; Lactic Acid; Male; Myoglobin; Postoperative Complications; Pyruvates; Pyruvic Acid | 1988 |
Graft transection and warm perfusion in situ in canine partial orthotopic liver transplantation.
Topics: Animals; Dogs; Energy Metabolism; Graft Survival; Ketone Bodies; Lactates; Lactic Acid; Liver; Liver Transplantation; Methods; Perfusion; Pyruvates; Pyruvic Acid; Temperature | 1988 |
Effects of tolbutamide on gluconeogenesis and glycolysis in isolated perfused rat liver.
Topics: Animals; Carbon Dioxide; Gluconeogenesis; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors; Tolbutamide | 1986 |
Pathways of acetone's metabolism in the rat.
Topics: Acetone; Acetyl Coenzyme A; Animals; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Female; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Valproate causes metabolic disturbance in normal man.
Topics: Acetoacetates; Administration, Oral; Blood Glucose; Chemical and Drug Induced Liver Injury; Humans; Injections, Intravenous; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sodium Oxybate; Valproic Acid | 1986 |
Substrate utilization for lactate and energy production by heat-shocked L929 cells.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Cell Line; Citric Acid Cycle; Energy Metabolism; Fibroblasts; Glucose; Glutamine; Heat-Shock Proteins; Lactates; Lactic Acid; Mice; NAD; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid; Temperature | 1986 |
Delayed treatment with nimodipine improves cerebral blood flow after complete cerebral ischemia in the dog.
Topics: Adenine Nucleotides; Animals; Blood; Blood Flow Velocity; Brain; Calcium Channel Blockers; Carbon Dioxide; Cerebrovascular Circulation; Dogs; Glucose; Hydrogen-Ion Concentration; Ischemic Attack, Transient; Kinetics; Lactates; Lactic Acid; Nicotinic Acids; Nimodipine; Pyruvates; Pyruvic Acid; Vascular Resistance | 1986 |
Therapeutic effects of a ketogenic diet in Rett syndrome.
Topics: Ammonia; Blood Glucose; Child; Child, Preschool; Dietary Fats; Electroencephalography; Energy Intake; Energy Metabolism; Female; Humans; Intellectual Disability; Ketosis; Lactates; Lactic Acid; Movement Disorders; Pyruvates; Pyruvic Acid; Seizures; Stereotyped Behavior; Syndrome; Triglycerides | 1986 |
Lactate metabolism in fetal type II pneumocytes.
Topics: Animals; Epithelium; Fetus; Lactates; Lactic Acid; Lung; Organ Culture Techniques; Oxygen; Pyruvates; Pyruvic Acid; Rats | 1986 |
Mechanisms and patterns of blood lactate increase during exercise in man.
Topics: Adult; Carbon Dioxide; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Muscles; Oxygen; Physical Exertion; Pyruvates; Pyruvic Acid | 1986 |
Intractable unphysiologically low adenylate energy charge values in synaptosome fractions: an explanatory hypothesis based on the fraction's heterogeneity.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Carbon Dioxide; Cell Fractionation; Chickens; Dogs; Energy Metabolism; Glucose; Humans; Lactates; Lactic Acid; Male; Mice; Oxygen Consumption; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
Effects of type of dietary fat and carbohydrate on gluconeogenesis in isolated hepatocytes from BHE rats.
Topics: Animals; Coconut Oil; Corn Oil; Dietary Carbohydrates; Dietary Fats; Gluconeogenesis; Lactates; Lactic Acid; Linoleic Acid; Linoleic Acids; Liver; Lysine; Male; Oils; Palmitic Acid; Palmitic Acids; Plant Oils; Pyruvates; Pyruvic Acid; Rats; Rats, Mutant Strains; Starch; Sucrose | 1986 |
A study of the effects of substrates on intracellular pH in toad ventricular strips.
Topics: Animals; Body Fluids; Bufo marinus; Carbon Dioxide; Coronary Disease; Glucose; Heart Ventricles; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid; Theophylline | 1986 |
Regulation of gluconeogenesis from pyruvate and lactate in the isolated perfused rat liver.
Topics: Animals; Carbon Dioxide; Glucagon; Gluconeogenesis; Glucose; Lactates; Lactic Acid; Liver; Male; Oxaloacetates; Phenylephrine; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Hepatic regeneration and metabolism after partial hepatectomy in diabetic rats: effects of insulin therapy.
Topics: Adenine Nucleotides; Animals; Diabetes Mellitus, Experimental; DNA; Glucose; Hepatectomy; Insulin; Lactates; Lactic Acid; Liver; Liver Glycogen; Liver Regeneration; Male; Organ Size; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Water | 1986 |
Long-term effects of nifedipine on carbohydrate and lipid metabolism in hypertensive hemodialyzed patients.
Topics: Adult; Blood Glucose; Cholesterol; Citrates; Citric Acid; Female; Glucagon; Humans; Hypertension, Renal; Insulin; Ketoglutaric Acids; Lactates; Lactic Acid; Lipids; Long-Term Care; Male; Middle Aged; Nifedipine; Pyruvates; Pyruvic Acid; Renal Dialysis; Triglycerides | 1986 |
Competition between fatty acids and carbohydrate or ketone bodies as metabolic fuels for the isolated perfused heart.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Caprylates; Carbohydrates; Carbon Dioxide; Fatty Acids; Glucose; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Male; Myocardium; Oleic Acid; Oleic Acids; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Deficiency of the reduced nicotinamide adenine dinucleotide dehydrogenase component of complex I of mitochondrial electron transport. Fatal infantile lactic acidosis and hypermetabolism with skeletal-cardiac myopathy and encephalopathy.
Topics: Acidosis, Lactic; Bone and Bones; Brain; Electron Transport; Energy Metabolism; Humans; Infant, Newborn; Lactates; Lactic Acid; Male; Mitochondria; Mitochondria, Muscle; Multienzyme Complexes; Myocardium; NAD(P)H Dehydrogenase (Quinone); NADH Dehydrogenase; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Quinone Reductases; Riboflavin | 1987 |
Cerebrospinal fluid lactate in patients with hepatic encephalopathy.
Topics: Acid-Base Equilibrium; Brain; Carbon Dioxide; Female; Glycolysis; Hepatic Encephalopathy; Humans; Lactates; Lactic Acid; Male; Middle Aged; Neurons; Pyruvates; Pyruvic Acid | 1987 |
Gluconeogenesis from serine in rabbit hepatocytes.
Topics: Animals; Cells, Cultured; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; NAD; Pyruvates; Pyruvic Acid; Rabbits; Serine; Urea | 1987 |
Valproate and lactate/pyruvate interactions.
Topics: Humans; Infant; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Valproic Acid | 1987 |
The production of lactate and pyruvate as sensitive indices of altered rat Sertoli cell function in vitro following the addition of various testicular toxicants.
Topics: Acetates; Animals; Cells, Cultured; Diethylhexyl Phthalate; Dinitrobenzenes; Ethylene Glycols; Follicle Stimulating Hormone; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sertoli Cells; Testis; Time Factors | 1988 |
A deficiency of both subunits of pyruvate dehydrogenase which is not expressed in fibroblasts.
Topics: Child, Preschool; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Humans; Immunoassay; Infant; Kidney; Lactates; Lactic Acid; Lymphocytes; Macromolecular Substances; Male; Mitochondria, Liver; Muscles; Myocardium; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid | 1988 |
Substrate exchange in human limb muscle during exercise at reduced blood flow.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aged; Arterial Occlusive Diseases; Arteries; Blood Glucose; Carbon Dioxide; Exercise; Fatty Acids, Nonesterified; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Leg; Male; Muscles; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Regional Blood Flow; Veins | 1988 |
Effect of valproate on renal metabolism in the intact dog.
Topics: Acid-Base Equilibrium; Acidosis; Ammonia; Animals; Biological Transport; Dogs; Kidney; Kidney Tubules; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Valproic Acid | 1988 |
Some enzymes and substrates of Embden-Meyerhof pathway of different tissues and related hormones of mycotoxin, MT81, treated mice.
Topics: Animals; Anthraquinones; Enzymes; Glucose; Hormones; Lactates; Lactic Acid; Male; Mice; Mycotoxins; Pyruvates; Pyruvic Acid | 1988 |
Acute toxicity of methyl isocyanate, administered subcutaneously in rabbits: changes in physiological, clinico-chemical and histological parameters.
Topics: 2,3-Diphosphoglycerate; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Cyanates; Diphosphoglyceric Acids; Electrocardiography; Female; Heart Rate; Injections, Subcutaneous; Isocyanates; Kidney; Lactates; Lactic Acid; Lethal Dose 50; Liver; Lung; Pyruvates; Pyruvic Acid; Rabbits; Respiration | 1988 |
Reconstitution of the L-lactate carrier from rat and rabbit erythrocyte plasma membranes.
Topics: Animals; Biological Transport; Carrier Proteins; Cholesterol; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; In Vitro Techniques; Lactates; Lactic Acid; Liposomes; Membrane Proteins; Monocarboxylic Acid Transporters; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rabbits; Rats | 1988 |
[Changes in lactate, pyruvate and the lactate/pyruvate quotient in cerebrospinal fluid in ischemic cerebrovascular accidents].
Topics: Adult; Aged; Cerebrovascular Disorders; Humans; Lactates; Lactic Acid; Middle Aged; Pyruvates; Pyruvic Acid | 1988 |
Effects of acute hypoxia and reoxygenation in a blood-perfused neonatal heart model.
Topics: Acute Disease; Animals; Animals, Newborn; Blood; Energy Metabolism; Heart; Hypoxia; Lactates; Lactic Acid; Myocardial Reperfusion; Myocardium; Perfusion; Phosphates; Pyruvates; Pyruvic Acid; Swine | 1988 |
Effect of recirculation on the recovery of cerebral metabolism after experimental cerebral ischemia in male and female spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Cerebral Arteries; Cerebrovascular Circulation; Constriction; Disease Models, Animal; Female; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred SHR; Sex Factors; Time Factors | 1988 |
Relations between pH, oxygen partial pressure and growth in cultured cell spheroids.
Topics: Animals; Cell Division; Cell Line; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Neoplasms; Neoplasms, Experimental; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Tumor Cells, Cultured | 1988 |
Control of gluconeogenesis: role of fatty acids in the alpha-adrenergic response.
Topics: Animals; Caprylates; Gluconeogenesis; Kinetics; Lactates; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Phenylephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Marked secretion of pyruvate in human duodenal juice stimulated with pancreozymin or secretin.
Topics: Adult; Bicarbonates; Cholecystokinin; Citrates; Citric Acid; Duodenum; Female; Humans; Intestinal Secretions; Lactates; Lactic Acid; Male; Middle Aged; Pancreas; Pancreatic Function Tests; Pyruvates; Pyruvic Acid; Secretin | 1988 |
Cerebral metabolic response to neonatal hypoglycemia in growth-retarded dogs.
Topics: Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Female; Fetal Growth Retardation; Glycogen; Hypoglycemia; Lactates; Lactic Acid; Phosphoenolpyruvate; Pregnancy; Pyruvates; Pyruvic Acid | 1988 |
Influence of hemorrhagic shock on hepatic energy metabolism in carbon tetrachloride-induced cirrhotic rats.
Topics: Adenine Nucleotides; Animals; Carbon Tetrachloride; Energy Metabolism; Kinetics; Lactates; Lactic Acid; Liver; Liver Cirrhosis, Experimental; Male; Mitochondria, Liver; Oxidation-Reduction; Phosphorylation; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Shock, Hemorrhagic | 1988 |
Modulation of the amino acid control of hepatic protein degradation by caloric deprivation. Two modes of alanine co-regulation.
Topics: Alanine; Amino Acids; Animals; Caprylates; Fasting; Lactates; Lactic Acid; Liver; Male; Perfusion; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Lew; Reference Values | 1988 |
The relationship of cardiac diastolic dysfunction to concurrent hormonal and metabolic status in type I diabetes mellitus.
Topics: Adult; Blood Glucose; Cardiomyopathies; Diabetes Mellitus, Type 1; Diastole; Epinephrine; Female; Glycated Hemoglobin; Hemodynamics; Humans; Insulin; Lactates; Lactic Acid; Male; Myocardial Contraction; Norepinephrine; Physical Exertion; Pyruvates; Pyruvic Acid; Systole | 1988 |
Short- and longer-term regulation of very-low-density lipoprotein secretion by insulin, dexamethasone and lipogenic substrates in cultured hepatocytes. A biphasic effect of insulin.
Topics: Animals; Cells, Cultured; Cholesterol; Dexamethasone; Insulin; Lactates; Lactic Acid; Lipids; Lipoproteins, VLDL; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors; Triglycerides | 1988 |
Muscle glycogen repletion during active postexercise recovery.
Topics: Alanine; Blood Glucose; Glycogen; Humans; Hydrogen-Ion Concentration; Insulin; Lactates; Lactic Acid; Male; Muscles; Physical Exertion; Pyruvates; Pyruvic Acid | 1987 |
Effect of high dose inhaled beclomethasone dipropionate on carbohydrate and lipid metabolism in normal subjects.
Topics: Administration, Inhalation; Adult; Beclomethasone; Blood Glucose; Carbohydrate Metabolism; Cholesterol; Cholesterol, HDL; Female; Glycerol; Humans; Insulin; Lactates; Lactic Acid; Lipid Metabolism; Male; Pyruvates; Pyruvic Acid; Reference Values | 1987 |
Effect of exercise on net hepatic uptake of lactate, pyruvate, alanine, and glycerol in sheep.
Topics: Alanine; Animals; Blood Glucose; Glucagon; Gluconeogenesis; Glycerol; Insulin; Lactates; Lactic Acid; Liver; Physical Exertion; Pyruvates; Pyruvic Acid; Regional Blood Flow; Sheep | 1987 |
Change from aerobic to anaerobic metabolism after brain death, and reversal following triiodothyronine therapy.
Topics: Aerobiosis; Anaerobiosis; Animals; Brain Death; Energy Metabolism; Fatty Acids, Nonesterified; Glucose; Lactates; Lactic Acid; Palmitates; Palmitic Acids; Papio; Postmortem Changes; Pyruvates; Pyruvic Acid; Triiodothyronine | 1988 |
The kinetics of transport of lactate and pyruvate into rat hepatocytes. Evidence for the presence of a specific carrier similar to that in erythrocytes.
Topics: Animals; Antimetabolites; Biological Transport; Cell Separation; Coumaric Acids; Erythrocytes; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
Partial attenuation of dentate granule cell evoked activity by the alternative substrates, lactate and pyruvate: evidence for a postsynaptic action.
Topics: Action Potentials; Animals; Electric Stimulation; Female; Guinea Pigs; Hippocampus; In Vitro Techniques; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1988 |
Metabolism of chloral hydrate in the anoxic perfused liver.
Topics: Animals; Chloral Hydrate; Lactates; Lactic Acid; Liver; Male; Oxygen; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
Synergistic effects of hypoxia and fasting on harmol elimination in the isolated perfused rat liver.
Topics: Alkaloids; Animals; Fasting; Glucose; Harmine; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Uridine Diphosphate Glucuronic Acid | 1988 |
Influence of the malate-aspartate shuttle on oxidative metabolism in synaptosomes.
Topics: Acetylcholine; Animals; Aspartate Aminotransferases; Aspartic Acid; Brain; Cytosol; Energy Metabolism; Glucose; Lactates; Lactic Acid; Malates; Male; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Mitochondrial encephalomyopathy with sleep apnea.
Topics: Brain Diseases; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondria; Muscles; Muscular Diseases; Pyruvates; Pyruvic Acid; Radiography; Sleep Apnea Syndromes; Ubiquinone | 1988 |
Brain levels of NADH and NAD+ under hypoxic and hypoglycaemic conditions in vitro.
Topics: Adenosine Triphosphate; Animals; Brain; Female; Glucose; Guinea Pigs; Hypoglycemia; Hypoxia, Brain; In Vitro Techniques; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Oxygen; Phosphocreatine; Pyruvates; Pyruvic Acid | 1988 |
[The effect of the ultrafiltration during and after cardiopulmonary bypass].
Topics: Adult; Body Fluids; Cardiopulmonary Bypass; Female; Heart Septal Defects, Atrial; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitral Valve; Pyruvates; Pyruvic Acid; Ultrafiltration | 1988 |
Respiratory and metabolic responses of fetal and neonatal perfused livers to catecholamines and anoxia.
Topics: Animals; Animals, Newborn; Female; Gluconeogenesis; Glycolysis; Guinea Pigs; In Vitro Techniques; Lactates; Lactic Acid; Liver; NAD; Norepinephrine; Oxidation-Reduction; Oxygen Consumption; Perfusion; Pregnancy; Pyruvates; Pyruvic Acid | 1988 |
Myocardial turnover of plasma free fatty acids during angina pectoris induced by atrial pacing.
Topics: Angina Pectoris; Blood Glucose; Cardiac Output; Coronary Vessels; Fatty Acids, Nonesterified; Humans; Lactates; Lactic Acid; Male; Middle Aged; Myocardium; Oleic Acid; Oleic Acids; Oxygen; Physical Exertion; Pyruvates; Pyruvic Acid; Rest | 1988 |
Metabolic interactions of parenchymal hepatocytes and dividing epithelial cells in co-culture.
Topics: Adult; Alanine; Albumins; Animals; Carnitine O-Palmitoyltransferase; Cells, Cultured; Epithelial Cells; Epithelium; Female; Glucose; Humans; Ketone Bodies; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
[Glucose, lactic acid and pyruvic acid levels of the blood and cerebrospinal fluid in patients with diabetes mellitus and cerebral infarction].
Topics: Aged; Blood Glucose; Cerebral Infarction; Diabetes Mellitus; Female; Glucose; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1987 |
Clinical and laboratory observations in a child with hepatic phosphorylase kinase deficiency.
Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Child, Preschool; Glycogen Storage Disease; Histocytochemistry; Humans; Hydroxybutyrates; Ketosis; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Phosphorylase Kinase; Pyruvates; Pyruvic Acid | 1986 |
Release of L-alanine by tumor cells.
Topics: Alanine; Animals; Cell Line; Glucose; Lactates; Lactic Acid; Leukemia L5178; Leukemia, Experimental; Lymphocyte Activation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Pyruvates; Pyruvic Acid; T-Lymphocytes, Cytotoxic | 1986 |
Glutamine is responsible for stimulating glycolysis by L929 cells.
Topics: Animals; Energy Metabolism; Glutamine; Glycolysis; Insulin; L Cells; Lactates; Lactic Acid; Mice; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1986 |
Intermediary metabolism in diabetic dogs treated with pancreatic autotransplants and insulin pumps.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Diabetes Mellitus, Experimental; Dogs; Fatty Acids, Nonesterified; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Lactates; Lactic Acid; Pancreas Transplantation; Pyruvates; Pyruvic Acid; Transplantation, Autologous | 1986 |
Metabolic effects of glucagon in endotoxemic minipigs.
Topics: Animals; Blood Glucose; Endotoxins; Escherichia coli; Glucagon; Gluconeogenesis; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; Liver; Liver Glycogen; Pyruvates; Pyruvic Acid; Swine; Swine, Miniature; Time Factors; Toxemia | 1986 |
Metabolic effects of low-dose incremental insulin infusion in diabetic man.
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glycerol; Humans; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1986 |
Metabolic rhythms in adolescents with diabetes during treatment with porcine or human insulin.
Topics: Adolescent; Animals; Blood Glucose; Child; Diabetes Mellitus, Type 1; Drug Administration Schedule; Female; Glycerol; Humans; Insulin; Insulin, Isophane; Insulin, Regular, Pork; Ketone Bodies; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid | 1986 |
Characteristics of rat hindlimbs perfused with erythrocyte- and albumin-free medium.
Topics: Adenine Nucleotides; Albumins; Animals; Bicarbonates; Buffers; Catecholamines; Erythrocytes; Female; Glucose; Hindlimb; Insulin; Lactates; Lactic Acid; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Net substrates balance across hindlimb in conscious rabbit during late pregnancy.
Topics: Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose; Hindlimb; Homeostasis; Insulin; Ketone Bodies; Lactates; Lactic Acid; Muscles; Oxygen Consumption; Pregnancy; Pregnancy, Animal; Pyruvates; Pyruvic Acid; Rabbits | 1986 |
Glucose turnover in response to exercise during high- and low-FIO2 breathing in man.
Topics: Adult; Blood Glucose; Epinephrine; Glucagon; Glucose; Humans; Insulin; Kinetics; Lactates; Lactic Acid; Male; Norepinephrine; Oxidation-Reduction; Oxygen; Physical Exertion; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid; Radioimmunoassay; Tritium | 1986 |
The metabolic and hormonal adaptations of normal dogs to long-term exogenous sulfated insulin infusions.
Topics: 3-Hydroxybutyric Acid; Adaptation, Physiological; Alanine; Animals; Blood Glucose; Circadian Rhythm; Dogs; Fatty Acids, Nonesterified; Gastric Inhibitory Polypeptide; Gastrins; Glucagon; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sulfates; Time Factors | 1986 |
Studies on the mechanism by which glutamine and heat shock increase lactate synthesis by L929 cells in the presence of insulin.
Topics: 3-O-Methylglucose; Aminooxyacetic Acid; Cell Line; Deoxyglucose; Glutamine; Glycolysis; Hot Temperature; Insulin; Kinetics; Lactates; Lactic Acid; Methylglucosides; Pyruvates; Pyruvic Acid; Transaminases | 1986 |
Short-term changes in blood ketone body ratio in the phase immediately after liver transplantation.
Topics: Animals; Female; Ketone Bodies; Lactates; Lactic Acid; Liver; Liver Transplantation; Male; Mitochondria, Liver; NAD; Postoperative Period; Preservation, Biological; Pyruvates; Pyruvic Acid; Swine; Tissue Preservation | 1987 |
Skeletal muscle glycogenolysis, glycolysis, and pH during electrical stimulation in men.
Topics: Adult; Electric Stimulation; Glycogen; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles; Osmolar Concentration; Pyruvates; Pyruvic Acid; Regional Blood Flow; Rest | 1987 |
"Pyruvate recycling" and its influence on the estimation of the pentose pathway in intact liver and Morris hepatoma 5123TC cells.
Topics: Animals; Carbon Radioisotopes; Dicarboxylic Acids; Dihydroxyacetone Phosphate; Female; Glucose; Glucose-6-Phosphate; Glucosephosphates; Lactates; Lactic Acid; Liver; Liver Neoplasms, Experimental; Male; Pentose Phosphate Pathway; Pyruvates; Pyruvic Acid; Rabbits; Rats; Rats, Inbred Strains; Tricarboxylic Acids | 1987 |
Ethanol-induced alteration in thiamin status of young turkey poults.
Topics: Animals; Body Weight; Erythrocytes; Ethanol; Heart; Lactates; Lactic Acid; Male; Organ Size; Pyruvates; Pyruvic Acid; Thiamine; Thiamine Pyrophosphate; Transketolase; Turkeys | 1987 |
[Hyperlactacidemia in intestinal ischemia. II. Experimental principles].
Topics: Animals; Intestines; Ischemia; Lactates; Lactic Acid; Mesenteric Vascular Occlusion; Necrosis; Pyruvates; Pyruvic Acid; Rabbits; Regional Blood Flow | 1987 |
Rate-limiting steps for protein synthesis in isolated rat liver cells. Role of aspartate availability.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Aspartic Acid; Cell Separation; Cycloserine; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Fatty Acids; Female; Glucose; Glutamine; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Macrophages; Mice; Mice, Inbred C57BL; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1987 |
Flow redistribution in a hyperdynamic small animal burn: comparison to patterns in sepsis.
Topics: Animals; Burns; Female; Infections; Lactates; Lactic Acid; Liver; Liver Circulation; Muscles; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Renal Circulation; Stress, Physiological | 1987 |
Cerebral metabolic responses of hyperglycemic immature rats to hypoxia-ischemia.
Topics: Adenine Nucleotides; Animals; Animals, Newborn; Blood Glucose; Brain; Brain Ischemia; Glucose; Hyperglycemia; Hypoxia, Brain; Lactates; Lactic Acid; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Effects of storage on the pyruvate-lactate system and random migration of human granulocytes.
Topics: Adenosine Triphosphate; Blood Preservation; Cell Movement; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Neutrophils; Pyruvates; Pyruvic Acid | 1987 |
Placental glycolysis and energy metabolism in preeclampsia.
Topics: Adenine Nucleotides; Energy Metabolism; Female; Fetal Growth Retardation; Glycolysis; Humans; Lactates; Lactic Acid; Placenta; Pre-Eclampsia; Pregnancy; Pyruvates; Pyruvic Acid | 1987 |
The importance of arginine 171 in substrate binding by Bacillus stearothermophilus lactate dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Geobacillus stearothermophilus; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mutation; Pyruvates; Pyruvic Acid; Structure-Activity Relationship; Substrate Specificity | 1987 |
Carbohydrate utilization by exercising muscle following pre-exercise glucose ingestion.
Topics: Adult; Alanine; Blood Glucose; Glucose; Glycogen; Humans; Lactates; Lactic Acid; Leg; Male; Muscles; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid | 1987 |
Composition of free fatty acids and adipose tissue triglycerides in portacaval shunted rats.
Topics: Adipose Tissue; Animals; Blood Glucose; Epididymis; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Ketone Bodies; Lactates; Lactic Acid; Male; Portacaval Shunt, Surgical; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Retroperitoneal Space; Triglycerides | 1987 |
Influence of hemodilution on hepatic energy metabolism in rat.
Topics: Adenine Nucleotides; Animals; Blood Pressure; Energy Metabolism; Hemodilution; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Effect of acetazolamide on renal metabolism and ammoniagenesis in the dog.
Topics: Acetazolamide; Acidosis; Ammonium Chloride; Animals; Chronic Disease; Citrates; Citric Acid; Dogs; Glutamine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Tubules; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Renal Circulation | 1987 |
The metabolite ratio as a function of chloral hydrate dose and intracellular redox state in the perfused rat liver.
Topics: Animals; Biotransformation; Chloral Hydrate; Dose-Response Relationship, Drug; Hemoglobins; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Perfusion; Pyridines; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence | 1987 |
In vivo nutrient uptake by head and neck cancers.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Glucose; Head and Neck Neoplasms; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Nutritional Physiological Phenomena; Pyruvates; Pyruvic Acid | 1987 |
Changes in cerebral glycogenolysis and related enzymes in diazinon treated hyperglycaemic animals.
Topics: Animals; Blood Glucose; Brain; Brain Chemistry; Cholinesterases; Diazinon; Female; Glycogen; Hyperglycemia; Insecticides; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rats | 1987 |
Acute responses of blood ketone body ratio following devascularization and revascularization of rabbit liver.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine Nucleotides; Animals; Energy Metabolism; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Liver; Liver Circulation; Male; Mitochondria, Liver; NAD; Pyruvates; Pyruvic Acid; Rabbits | 1987 |
[Experimental studies of the effect of propranolol on the metabolism of the human placenta with regard to the production of lactic and pyruvic acids].
Topics: Depression, Chemical; Female; Humans; In Vitro Techniques; Lactates; Lactic Acid; Placenta; Pregnancy; Propranolol; Pyruvates; Pyruvic Acid | 1987 |
[Adaptation of peripheral circulation to isolated calf muscle stress and its relation to blood gases and substrate concentrations in femoral and popliteal venous blood in patients with occlusive disease].
Topics: Arterial Occlusive Diseases; Femoral Vein; Humans; Lactates; Lactic Acid; Leg; Male; Middle Aged; Muscles; Physical Exertion; Popliteal Vein; Pyruvates; Pyruvic Acid; Regional Blood Flow | 1987 |
Redox state and lactate accumulation in human skeletal muscle during dynamic exercise.
Topics: Adenine Nucleotides; Adult; Cytosol; Glycerophosphates; Glycolysis; Humans; Lactates; Lactic Acid; Male; Muscles; NAD; Oxidation-Reduction; Physical Exertion; Pyruvates; Pyruvic Acid | 1987 |
Stimulation by glucose of gluconeogenesis in hepatocytes isolated from starved rats.
Topics: Animals; Glucagon; Gluconeogenesis; Glucose; Glycerol; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Stimulation, Chemical | 1987 |
Electrochemically treated glassy carbon electrode for amperometric detection in high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Electrodes; Gout; Humans; Lactates; Lactic Acid; Oxypurinol; Phosphates; Pyruvates; Pyruvic Acid; Renal Dialysis; Tyrosine | 1987 |
[Biochemical factors in the pathogenesis of autonomic crises].
Topics: Adult; Autonomic Nervous System Diseases; Female; Galvanic Skin Response; Heart Rate; Humans; Lactates; Lactic Acid; Male; Personality Tests; Physical Exertion; Pyruvates; Pyruvic Acid; Respiration | 1987 |
[Isolated perfusion of the small intestine of the rat with perfluorotributylamine as an artificial oxygen carrier].
Topics: Animals; Energy Metabolism; Fluorocarbons; Intestinal Absorption; Intestine, Small; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats | 1987 |
[Changes in organic acids in plasma and cerebrospinal fluid in cerebral infarct].
Topics: Aged; Aged, 80 and over; Blood-Brain Barrier; Cerebral Infarction; Citrates; Citric Acid; Female; Follow-Up Studies; Fumarates; Humans; Keto Acids; Ketoglutaric Acids; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1987 |
Assessment of the toxicity of chemical mixtures with isolated rat hepatocytes: cadmium and chloroform.
Topics: Animals; Aspartate Aminotransferases; Cadmium Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Potassium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Influence of hypoxia and an acidic environment on the metabolism and viability of cultured cells: potential implications for cell death in tumors.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Cricetinae; Cricetulus; Energy Metabolism; Glucose; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Neoplasms; Oxygen; Pyruvates; Pyruvic Acid | 1986 |
Effect of lactate, pyruvate, and pH on secretion of angiogenesis and mitogenesis factors by macrophages.
Topics: Angiogenesis Inducing Agents; Animals; Biological Assay; Cells, Cultured; Cornea; DNA; Growth Substances; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Macrophages; Mitogens; Pyruvates; Pyruvic Acid; Rabbits | 1986 |
Hepatic UDP-glucuronic acid regulation during acetaminophen biotransformation in rats.
Topics: Acetaminophen; Animals; Biotransformation; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; NAD; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Salicylamides; Uridine Diphosphate Glucose; Uridine Diphosphate Glucose Dehydrogenase; Uridine Diphosphate Glucuronic Acid; Uridine Diphosphate Sugars | 1986 |
[Characteristics of changes in acid-base equilibrium and the level of underoxidized products of metabolism during surgery and in the early postoperative period in patients with surgical diseases of the adrenal glands].
Topics: Acid-Base Equilibrium; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Child; Child, Preschool; Cushing Syndrome; Humans; Intraoperative Period; Lactates; Lactic Acid; Middle Aged; Pheochromocytoma; Postoperative Period; Pyruvates; Pyruvic Acid | 1986 |
Hormonal and metabolic profiles in patients with alcohol-induced, mixed hypertriglyceridemia before and after abstinence from ethanol and before and after a lipid-lowering diet.
Topics: Adult; Blood Glucose; Circadian Rhythm; Dietary Fats; Ethanol; Fatty Acids, Nonesterified; Hormones; Humans; Hyperlipidemias; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Triglycerides | 1986 |
Acclimation to sublethal acidic and alkaline media of Tilapia mossambica (Peters): changes in glycogen metabolism of red muscle.
Topics: Adaptation, Physiological; Animals; Fishes; Fresh Water; Fructose-Bisphosphate Aldolase; Glucose; Glycogen; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Muscles; Pyruvates; Pyruvic Acid | 1986 |
Different types of postinsulin receptor defects contribute to insulin resistance in hearts of obese Zucker rats.
Topics: Adenine Nucleotides; Animals; Energy Metabolism; Epoxy Compounds; Glucose; Insulin Resistance; Lactates; Lactic Acid; Lipolysis; Male; Myocardium; Obesity; Oxidation-Reduction; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker; Receptor, Insulin | 1986 |
A 1H-NMR study of the activity expressed by lactate dehydrogenase in the human erythrocyte.
Topics: Erythrocytes; Glycylglycine; Humans; Imidazoles; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Pyruvates; Pyruvic Acid | 1986 |
The concerted effect of alpha-chlorohydrin and glucose on the ATP concentration in spermatozoa is associated with the accumulation of glycolytic intermediates.
Topics: Adenosine Triphosphate; alpha-Chlorohydrin; Animals; Chlorohydrins; Fructose; Glucose; Lactates; Lactic Acid; Male; Mannose; Pyruvates; Pyruvic Acid; Sheep; Spermatozoa; Swine | 1986 |
Contraction and metabolic activity of electrically stimulated cardiac myocytes from adult rats.
Topics: Animals; Electric Stimulation; Glucose; In Vitro Techniques; Isoproterenol; Lactates; Lactic Acid; Methods; Myocardial Contraction; Myocardium; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats | 1986 |
Effective organ blood flow and bioenergy status in murine peritonitis.
Topics: Adenosine Triphosphate; Animals; Cardiac Output; Cecum; Energy Metabolism; Female; Kidney; Lactates; Lactic Acid; Ligation; Liver; Liver Circulation; Muscles; Peritonitis; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Renal Circulation | 1986 |
Effect of coupling of 2-nor-2-formylpyridoxal 5'-phosphate to stroma-free hemoglobin on oxygen affinity and tissue oxygenation. Studies in the isolated perfused rat liver under conditions of normoxia and stagnant hypoxia.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Cross-Linking Reagents; Hemoglobins; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Oxygen; Oxygen Consumption; Perfusion; Plasma Substitutes; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Differential effect of glucagon on gluconeogenesis in periportal and pericentral regions of the liver lobule.
Topics: Animals; Female; Glucagon; Gluconeogenesis; Lactates; Lactic Acid; Liver; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Tissue Distribution | 1986 |
The role of the hepatocellular redox state in the hepatic triglyceride accumulation following acute ethanol administration.
Topics: Acetaldehyde; Animals; Ethanol; Lactates; Lactic Acid; Lipid Metabolism; Liver; Male; NAD; Naloxone; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol; Triglycerides | 1986 |
2-Cyanocinnamic acid sensitization of L929 cells to killing by hyperthermia.
Topics: Biological Transport; Cell Survival; Cells, Cultured; Cinnamates; Heat-Shock Proteins; Hyperthermia, Induced; Lactates; Lactic Acid; Monocarboxylic Acid Transporters; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1986 |
[Circadian profiles of lactic and pyruvic acid in diabetic patients treated with biguanides and sulfonylureas].
Topics: Aged; Biguanides; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Diet, Diabetic; Humans; Lactates; Lactic Acid; Middle Aged; Pyruvates; Pyruvic Acid; Sulfonylurea Compounds | 1986 |
Influence of various substrates on the acetylcarnitine:carnitine ratio in motile and immotile human spermatozoa.
Topics: Acetylcarnitine; Acylation; Carnitine; Cells, Cultured; Culture Media; Humans; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sperm Motility; Spermatozoa | 1986 |
Methotrexate increases glycogenolysis in the intact rat liver.
Topics: Animals; Dose-Response Relationship, Drug; Glucose; Glycogen; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Methotrexate; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Effects of alanine on malate-aspartate shuttle in perfused livers from cold-exposed rats.
Topics: Adrenalectomy; Alanine; Alanine Transaminase; Aminooxyacetic Acid; Animals; Asparagine; Aspartic Acid; Cold Temperature; Dexamethasone; Ethanol; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol | 1986 |
Rapid assay of pyruvate with a centrifugal analyser using a commercially available test kit.
Topics: Centrifugation; Humans; Indicators and Reagents; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Reagent Kits, Diagnostic | 1986 |
Effective renal blood flow and renal energy charge in murine peritonitis.
Topics: Adenine Nucleotides; Animals; Cardiac Output; Energy Metabolism; Female; Kidney; Lactates; Lactic Acid; Peritonitis; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Renal Circulation; Time Factors | 1986 |
[Protective effect of thromboxane A2 synthetase inhibitor (trapidil) on acutely-induced cerebral ischemia].
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Cerebral Arteries; Lactates; Lactic Acid; Male; Microscopy, Electron, Scanning; Pyrimidines; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred SHR; Thromboxane B2; Thromboxane-A Synthase; Trapidil | 1986 |
Renal effects of dichloroacetate in vivo.
Topics: Acetates; Acidosis, Lactic; Administration, Oral; Child, Preschool; Dichloroacetic Acid; Gas Chromatography-Mass Spectrometry; Humans; Kidney; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid | 1986 |
Reduction-oxidation state and protein degradation in skeletal muscles of growing rats.
Topics: Animals; Body Weight; Lactates; Lactic Acid; Male; Muscle Development; Muscle Proteins; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Branched-chain amino acid carbon and nitrogen arteriovenous concentration differences across the ovine fetal hindlimb.
Topics: Amino Acids, Branched-Chain; Animals; Blood Glucose; Extremities; Female; Fetus; Lactates; Lactic Acid; Maternal-Fetal Exchange; Nitrogen; Pregnancy; Pyruvates; Pyruvic Acid; Sheep | 1987 |
[A study on the usefulness of continuous monitoring of myocardial pH in myocardial protection].
Topics: Animals; Coronary Circulation; Dogs; Heart Arrest, Induced; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Monitoring, Physiologic; Myocardium; Pyruvates; Pyruvic Acid | 1986 |
Effects of in vitro anoxia and low pH on acetylcholine release by rat brain synaptosomes.
Topics: Acetylcholine; Animals; Brain; Calcium; Choline; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Male; Oxygen Consumption; Potassium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Synaptosomes | 1987 |
The effect of fatty acids and starvation on the metabolism of gluconeogenic precursors by isolated sheep liver cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Cell Separation; Fatty Acids; Gluconeogenesis; Hydroxybutyrates; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Sheep; Starvation | 1986 |
Lactate and pyruvate electrochemical biosensors for whole blood in extracorporeal experiments with an endocrine artificial pancreas.
Topics: Blood Glucose; Electrochemistry; Enzymes, Immobilized; Humans; Hydrogen Peroxide; Insulin Infusion Systems; Lactates; Lactic Acid; Mixed Function Oxygenases; Monitoring, Physiologic; Pyruvate Oxidase; Pyruvates; Pyruvic Acid | 1987 |
Early onset myophosphorylase deficiency (Mc Ardle's disease) with absence of myophosphorylase protein on SDS electrophoresis. The role of the ischemic forearm test.
Topics: Adult; Biopsy; Electromyography; Electrophoresis, Polyacrylamide Gel; Exercise Test; Female; Forearm; Glycogen Storage Disease; Glycogen Storage Disease Type V; Histocytochemistry; Humans; Ischemia; Lactates; Lactic Acid; Phosphorylases; Pyruvates; Pyruvic Acid | 1985 |
Acute stimulation by glucocorticoids of gluconeogenesis from lactate/pyruvate in isolated hepatocytes from normal and adrenalectomized rats.
Topics: Adrenalectomy; Angiotensin II; Animals; Corticosterone; Cortodoxone; Cycloheximide; Deoxyadenosines; Dexamethasone; Glucagon; Glucocorticoids; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; Progesterone; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Plasmodium berghei: gluconeogenesis in the infected mouse liver studied by 13C nuclear magnetic resonance.
Topics: Animals; Blood Glucose; Gluconeogenesis; Lactates; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Malaria; Male; Mice; Plasmodium berghei; Pyruvates; Pyruvic Acid | 1985 |
Food-induced thermogenesis in obese children.
Topics: Adolescent; Blood Glucose; Body Temperature Regulation; Child; Energy Metabolism; Fatty Acids, Nonesterified; Female; Food; Growth Hormone; Humans; Insulin; Lactates; Lactic Acid; Male; Obesity; Pyruvates; Pyruvic Acid | 1985 |
Effect of drugs, peptide hormones and lipogenic precursors on the relative incorporation of [3H]H2O and carbon into hepatic cholesterol.
Topics: Animals; Carbon; Cholesterol; Citrates; Fasting; Glucagon; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Rats; Tritium | 1985 |
[Alcohol and metabolism].
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Amino Acids; Blood Glucose; Cholesterol; Energy Metabolism; Ethanol; Hormones; Humans; Lactates; Lactic Acid; Liver; Metabolic Clearance Rate; Porphyrins; Proteins; Pyruvates; Pyruvic Acid; Triglycerides | 1985 |
Carbohydrate metabolism in potassium-depleted rats.
Topics: Acetoacetates; Animals; Blood Glucose; Carbohydrate Metabolism; Female; Glucose; Glycogen; Insulin; Ketoglutaric Acids; Kidney; Lactates; Lactic Acid; Liver; Muscles; Myocardium; Potassium; Potassium Deficiency; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation | 1985 |
Effect of taurine depletion and treatment on cardiac contractility and metabolism.
Topics: Animals; Glucose; Heart; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Taurine | 1985 |
Effect of glucose and insulin administration on hepatic adenylate energy charge and the cytosolic redox state in the neonates of normal and insulin-treated diabetic rats.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Animals, Newborn; Cytosol; Diabetes Mellitus, Experimental; Energy Metabolism; Female; Glucose; Insulin; Lactates; Lactic Acid; Liver; NAD; Oxidation-Reduction; Pregnancy; Pregnancy in Diabetics; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Role of insulin in regulating hepatic gluconeogenesis in sheep.
Topics: Animals; Female; Gluconeogenesis; Glucose; Glycerol; Injections, Intravenous; Insulin; Kinetics; Lactates; Lactic Acid; Liver; Liver Circulation; Portal Vein; Pyruvates; Pyruvic Acid; Sheep | 1985 |
High density mammalian cell growth in Leibovitz bicarbonate-free medium: effects of fructose and galactose on culture biochemistry.
Topics: Ammonia; Animals; Cell Count; Cell Line; Chlorocebus aethiops; Culture Media; Cytological Techniques; Dogs; Fructose; Galactose; Hydrogen-Ion Concentration; Kidney; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1985 |
Effect of tourniquet ischaemia on carbohydrate metabolism of dog skeletal muscle.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Citrates; Citric Acid; Dogs; Energy Metabolism; Female; Glycogen; Glycogen Synthase; Glycolysis; Hydroxybutyrates; Ischemia; Ketoglutaric Acids; Lactates; Lactic Acid; Lysosomes; Male; Muscles; Phosphorylases; Pyruvates; Pyruvic Acid; Tourniquets | 1985 |
Monocarboxylate-uptake kinetics in perfused rat heart.
Topics: Animals; Carrier Proteins; Kinetics; Lactates; Lactic Acid; Male; Mannitol; Monocarboxylic Acid Transporters; Myocardium; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Software | 1985 |
The rate of protein degradation in isolated skeletal muscle does not correlate with reduction-oxidation status.
Topics: Animals; Calcimycin; Calcium; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Male; Muscle Contraction; Muscle Proteins; Muscles; Oxidation-Reduction; Protease Inhibitors; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Temperature | 1985 |
Metabolic effects in rats of high oral doses of galactitol, mannitol and xylitol.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Corticosterone; Food Additives; Galactitol; Glucagon; Hemoglobins; Insulin; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Mannitol; Metabolism; Pyruvates; Pyruvic Acid; Rats; Sugar Alcohols; Triglycerides; Xylitol | 1985 |
The biochemical complex of ischemic damage to the central nervous system.
Topics: Bicarbonates; Carbon Dioxide; Catecholamines; Cerebrovascular Disorders; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1985 |
A reexamination of the role of the cytosolic alanine aminotransferase in hepatic gluconeogenesis.
Topics: Acetates; Acetic Acid; Alanine; Alanine Transaminase; Animals; Carbon Dioxide; Cinnamates; Cytosol; Gluconeogenesis; Isoenzymes; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Monocarboxylic Acid Transporters; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
[Respiratory enzyme activity in the thyroid tissue of toxic goiter patients receiving lithium carbonate before surgery].
Topics: Cytochrome Reductases; Goiter, Nodular; Graves Disease; Humans; Iodide Peroxidase; Lactates; Lactic Acid; Lithium; Lithium Carbonate; Methimazole; NADH Dehydrogenase; Oxidation-Reduction; Preoperative Care; Pyruvates; Pyruvic Acid; Succinate Dehydrogenase; Thyroid Gland; Thyroidectomy | 1985 |
The effects of cyclopropane carboxylate on hepatic pyruvate metabolism.
Topics: Acyl Coenzyme A; Animals; Carbon Dioxide; Cyclopropanes; Gluconeogenesis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Brain metabolism in deep controlled hypotension in neurosurgical patients.
Topics: Adult; Brain; Female; Humans; Hypotension, Controlled; Intracranial Aneurysm; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Middle Aged; Nitroglycerin; Oxygen; Pyruvates; Pyruvic Acid | 1985 |
[Mitochondrial myopathies and encephalomyopathies. Neuromuscular and central nervous system diseases caused by defects in mitochondrial oxidative metabolism].
Topics: Brain; Brain Diseases, Metabolic; Carnitine O-Acetyltransferase; Child; Citric Acid Cycle; Cytochromes; Energy Metabolism; Enzymes; Humans; Lactates; Lactic Acid; Mitochondria, Muscle; Muscles; NAD; Neuromuscular Diseases; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid | 1985 |
Utilization of pyruvate and pyruvate precursors by normal and carcinogen-altered rat tracheal epithelial cells in culture.
Topics: Alanine; Animals; Carbon Radioisotopes; Cells, Cultured; Glucose; Glutamine; Glycolysis; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Trachea; Tracheal Neoplasms | 1986 |
Effects of intravenous glycerol on cerebral blood flow and tissue metabolism in acute cerebral ischemia in spontaneously hypertensive rats.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Glycerol; Infusions, Parenteral; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred SHR | 1986 |
Metabolic rhythms in adolescents with diabetes.
Topics: Activity Cycles; Adolescent; Blood Glucose; Child; Circadian Rhythm; Diabetes Mellitus, Type 1; Female; Glycerol; Humans; Ketone Bodies; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Self Care | 1986 |
Effects of alloxan-induced diabetes mellitus on the metabolism of the rat placenta.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glycogen; Lactates; Lactic Acid; Placenta; Pregnancy; Pregnancy in Diabetics; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Influence of sulphite on the release of glycolytic metabolites in the perfused rat liver.
Topics: Animals; Glycolysis; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sulfites | 1986 |
Secretion of pyruvate and lactate in pancreatic juice induced by acetazolamide or secretin.
Topics: Acetazolamide; Animals; Bicarbonates; Dogs; Dose-Response Relationship, Drug; Female; Lactates; Lactic Acid; Male; Models, Biological; Pancreatic Juice; Pyruvates; Pyruvic Acid; Secretin | 1986 |
Rate equations and kinetics of uptake of alpha-aminoisobutyric acid and gamma-aminobutyric acid by mouse cerebrum slices incubated in media containing L(+)-lactate or a mixture of succinate, L-malate, and pyruvate as the energy source.
Topics: Aminoisobutyric Acids; Animals; Biological Transport, Active; Brain; Energy Metabolism; gamma-Aminobutyric Acid; Glucose; Kinetics; Lactates; Lactic Acid; Malates; Male; Mice; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid | 1985 |
Changes in brain energy metabolism and protein synthesis following transient bilateral ischemia in the gerbil.
Topics: Adenine Nucleotides; Animals; Brain; Energy Metabolism; Gerbillinae; Glycogen; Guanine Nucleotides; Ischemic Attack, Transient; Kinetics; Lactates; Lactic Acid; Male; NADP; Nerve Tissue Proteins; Pentobarbital; Phosphocreatine; Pyruvates; Pyruvic Acid | 1985 |
Interrelation between salvage of purine nucleotides and protein synthesis in rat heart cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Fibroblasts; Humans; Lactates; Lactic Acid; Methylphenazonium Methosulfate; Muscle Proteins; Myocardium; Oxygen Consumption; Purine Nucleotides; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
[Metabolic changes in muscle and blood caused by ergometric stress in chronic arterial occlusive disease (I)].
Topics: Adenosine Triphosphate; Arterial Occlusive Diseases; Energy Metabolism; Humans; Lactates; Lactic Acid; Male; Middle Aged; Muscles; Phosphocreatine; Physical Exertion; Pyruvates; Pyruvic Acid | 1985 |
[Muscle metabolism and blood circulation under ergometric stress in arterial occlusive disease (II)].
Topics: Arterial Occlusive Diseases; Energy Metabolism; Humans; Lactates; Lactic Acid; Male; Middle Aged; Muscles; Physical Exertion; Pyruvates; Pyruvic Acid; Regional Blood Flow | 1985 |
Why does brain make lactate?
Topics: Animals; Brain; Glucose; Lactates; Lactic Acid; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats | 1985 |
[Linearity of the lactate dehydrogenase reaction. 1. Reaction direction pyruvate----lactate (P----L)].
Topics: Humans; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Myocardium; Pyruvates; Pyruvic Acid | 1985 |
Vascular perfusion: a novel means of studying oviduct function.
Topics: Amino Acids; Animals; Fallopian Tubes; Female; Fertilization; Glucose; Lactates; Lactic Acid; Methods; Ovum Transport; Perfusion; Pyruvates; Pyruvic Acid; Rabbits | 1985 |
Characteristics of lactate transfer in isolated cardiac myocytes.
Topics: Animals; Blood Glucose; Cell Membrane Permeability; Cells, Cultured; Extracellular Space; Female; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sarcolemma | 1985 |
Red blood cell oxidative metabolism induced by hydroxypyruvaldehyde.
Topics: Adult; Blood Glucose; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Humans; In Vitro Techniques; Lactates; Lactic Acid; Malonates; Malondialdehyde; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Pentose Phosphate Pathway; Pyruvaldehyde; Pyruvates; Pyruvic Acid | 1985 |
Effect of hypoxia on oxidative and reductive pathways of omeprazole metabolism by the isolated perfused rat liver.
Topics: Animals; Benzimidazoles; Hypoxia; Lactates; Lactic Acid; Liver; Male; Omeprazole; Oxidation-Reduction; Oxygen; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Energy metabolism during mammalian embryogenesis.
Topics: Animals; Blastocyst; Citric Acid Cycle; Embryo, Mammalian; Embryonic and Fetal Development; Energy Metabolism; Glucose; Lactates; Lactic Acid; Mice; Pyruvates; Pyruvic Acid; Rats | 1985 |
Laboratory approaches for inherited neurometabolic diseases.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Galactosemias; Homocystinuria; Humans; Lactates; Lactic Acid; Lipid Metabolism, Inborn Errors; Lysosomes; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Metals; Phenylketonurias; Pyruvates; Pyruvic Acid | 1985 |
Biochemical differences between perilymph, cerebrospinal fluid and blood plasma in the guinea pig.
Topics: Animals; Blood Chemical Analysis; Blood Glucose; Blood Proteins; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Glucose; Guinea Pigs; L-Lactate Dehydrogenase; Labyrinthine Fluids; Lactates; Lactic Acid; Perilymph; Potassium; Proteins; Pyruvates; Pyruvic Acid; Sodium | 1985 |
Role of energy charge and redox state for hepatocyte gluconeogenesis of acutely uremic rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Energy Metabolism; Female; Gluconeogenesis; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Liver; Nephrectomy; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Uremia | 1985 |
Energy sources in fully aerobic rest-work transitions: a new role for glycolysis.
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Dogs; Energy Metabolism; Female; Glycolysis; Lactates; Lactic Acid; Male; Mathematics; Muscles; Oxidation-Reduction; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid | 1985 |
A kinetic model for the interaction of energy metabolism and osmotic states of human erythrocytes. Analysis of the stationary "in vivo" state and of time dependent variations under blood preservation conditions.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Biological Transport, Active; Blood Preservation; Chlorides; Energy Metabolism; Erythrocytes; Glycolysis; Humans; Hydrogen; Kinetics; Lactates; Lactic Acid; Models, Biological; Osmolar Concentration; Oxidation-Reduction; Potassium; Pyruvates; Pyruvic Acid; Sodium; Time Factors | 1985 |
Effect of various substrates on mitochondrial and cellular energy state of intact spermatozoa.
Topics: Acetates; Acetic Acid; Adenine Nucleotides; Animals; Cattle; Energy Metabolism; Glycerol; In Vitro Techniques; Lactates; Lactic Acid; Male; Mitochondria; Oxygen Consumption; Pyruvates; Pyruvic Acid; Sperm Motility; Spermatozoa | 1985 |
The rates of defined changes in protein structure during the catalytic cycle of lactate dehydrogenase.
Topics: Animals; Chemical Phenomena; Chemistry; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Protein Conformation; Pyruvates; Pyruvic Acid; Swine | 1985 |
Inhibition of recovery from potentially lethal damage by chemicals in Chinese hamster V79 A cells.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Repair; Dose-Response Relationship, Radiation; In Vitro Techniques; Lactates; Lactic Acid; Mutation; Nalidixic Acid; Novobiocin; Pyruvates; Pyruvic Acid | 1985 |
[Indicators of exertion metabolism in parturients].
Topics: Female; Humans; Labor, Obstetric; Lactates; Lactic Acid; Oxygen Consumption; Physical Exertion; Pregnancy; Pyruvates; Pyruvic Acid; Uterine Contraction | 1985 |
[Relation between glycohemoglobin, hypoxia parameters and diabetic microangiopathy].
Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Retinopathy; Diphosphoglyceric Acids; Erythrocytes; Female; Glycated Hemoglobin; Hemoglobinometry; Humans; Hypoxia; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid | 1985 |
[Energy metabolism of the myometrium in pregnancy and labor].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glycogen; Humans; Labor, Obstetric; Lactates; Lactic Acid; Myometrium; Pregnancy; Pyruvates; Pyruvic Acid | 1985 |
Metabolic adaptation to reduced muscle blood flow. II. Mechanisms and beneficial effects.
Topics: Adaptation, Physiological; Adenine Nucleotides; Animals; Creatine; Electric Stimulation; Female; Glycogen; Lactates; Lactic Acid; Ligation; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion; Phosphocreatine; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Regional Blood Flow | 1985 |
Effects of anesthetics on regional hemodynamics in normovolemic and hemorrhaged rats.
Topics: Anesthesia, General; Anesthetics; Animals; Blood Pressure; Cardiac Output; Cerium Radioisotopes; Chloralose; Decerebrate State; Heart Rate; Hemodynamics; Hemorrhage; Lactates; Lactic Acid; Male; Microspheres; Pentobarbital; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Regional Blood Flow; Vascular Resistance | 1985 |
Metabolic control of renal vascular resistance and glomerulotubular balance.
Topics: Amino Acids; Animals; Biological Transport, Active; Glomerular Filtration Rate; Gluconeogenesis; Glucose; Hydrostatic Pressure; Kidney; Kidney Concentrating Ability; Kidney Tubules, Proximal; Lactates; Lactic Acid; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Renal Artery; Renal Veins; Sodium; Vascular Resistance; Vasodilation | 1985 |
Effects of intravenous ritodrine on lactate and pyruvate levels: role of glycemia and anaerobiosis.
Topics: Anaerobiosis; Blood Glucose; Female; Humans; Lactates; Lactic Acid; Metabolism; Obstetric Labor, Premature; Pregnancy; Propanolamines; Pyruvates; Pyruvic Acid; Ritodrine | 1985 |
Different metabolites might reduce food intake by the mitochondrial generation of reducing equivalents.
Topics: Animals; Dihydroxyacetone; Eating; Energy Metabolism; Glycerol; Lactates; Lactic Acid; Malates; Male; Mitochondria, Liver; Oxaloacetates; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Estimation of a derivative by a difference quotient: its application to hepatocyte lactate metabolism.
Topics: Animals; Biometry; In Vitro Techniques; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Rats | 1985 |
Change in metabolite concentration of tears after short-term wearing of contact lenses in nonadapted eyes.
Topics: Blood Glucose; Cell Membrane Permeability; Contact Lenses; Cornea; Corneal Injuries; Epithelium; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Tears | 1985 |
Epidural diamorphine and the metabolic response to upper abdominal surgery.
Topics: Blood Glucose; Cholecystectomy; Epidural Space; Fatty Acids, Nonesterified; Female; Heroin; Humans; Hydrocortisone; Lactates; Lactic Acid; Male; Metabolism; Middle Aged; Opium; Pain, Postoperative; Pyruvates; Pyruvic Acid | 1985 |
Redox status of cultured fibroblasts. Possible relations with specific catabolic rates of proteoglycans.
Topics: Aerobiosis; Anaerobiosis; Animals; Cells, Cultured; Fibroblasts; Glycolysis; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Proteoglycans; Pyruvates; Pyruvic Acid; Rats | 1985 |
Effect of denervation on the glycolytic metabolism of the main electric organ of Electrophorus electricus (L.).
Topics: Adenosine Triphosphate; Animals; Creatine Kinase; Electric Organ; Electrophorus; Glycolysis; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Malate Dehydrogenase; Pyruvates; Pyruvic Acid | 1985 |
An in vitro approach to the study of target organ toxicity of drugs and chemicals.
Topics: Acetaminophen; Animals; Antidepressive Agents, Tricyclic; Biotransformation; Cell Survival; Cells, Cultured; Cephaloridine; Heart; Isoproterenol; Kidney Cortex; Lactates; Lactic Acid; Liver; Metals; Myocardial Contraction; Myocardium; Pyruvates; Pyruvic Acid; Rats; Toxicology; Urea | 1985 |
The interaction between the cytosolic pyridine nucleotide redox potential and gluconeogenesis from lactate/pyruvate in isolated rat hepatocytes. Implications for investigations of hormone action.
Topics: Angiotensin II; Animals; Cytosol; Dexamethasone; Glucagon; Gluconeogenesis; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; Lactates; Lactic Acid; Liver; Malate Dehydrogenase; Male; NAD; Oxaloacetates; Oxidation-Reduction; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Estimation of the relative contributions of enhanced production of oxalacetate and inhibition of pyruvate kinase to acute hormonal stimulation of gluconeogenesis in rat hepatocytes. An analysis of the effects of glucagon, angiotensin II, and dexamethasone
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin II; Animals; Cytosol; Dexamethasone; Glucagon; Glucocorticoids; Gluconeogenesis; Glyceric Acids; Hormones; Kinetics; Lactates; Lactic Acid; Liver; Male; NAD; Oxaloacetates; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Subacute necrotizing encephalomyelopathy (Leigh syndrome) associated with disturbed oxidation of pyruvate, malate and 2-oxoglutarate in muscle and liver.
Topics: Adolescent; Brain; Brain Diseases, Metabolic; Enzymes; Female; Humans; Ketoglutaric Acids; Lactates; Lactic Acid; Leigh Disease; Liver; Malates; Muscles; Oxidation-Reduction; Phosphorylation; Pyruvates; Pyruvic Acid; Spinal Cord | 1985 |
The concentration of blood components related to fuel metabolism during prolonged fasting in children.
Topics: Adolescent; Age Factors; Alanine; Blood Chemical Analysis; Blood Glucose; Child; Child, Preschool; Energy Metabolism; Fasting; Fatty Acids, Nonesterified; Female; Humans; Ketone Bodies; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sex Factors; Time Factors; Triglycerides | 1985 |
Canine liver isolation-perfusion at normo- and hyperthermic temperatures with perfluorochemical emulsion (Fluosol-43).
Topics: Alanine Transaminase; Animals; Blood Substitutes; Dogs; Fluorocarbons; Hydrogen-Ion Concentration; Ketone Bodies; Lactates; Lactic Acid; Liver; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Temperature; Time Factors | 1985 |
Multiple requirements for glycogen synthesis by hepatocytes isolated from fasted rats.
Topics: Amino Acids, Branched-Chain; Animals; Cycloheximide; Deoxyglucose; Dihydroxyacetone; Fasting; Glucose; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Puromycin; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Laboratory evaluation of patients with vascular occlusive disease.
Topics: Adenosine Triphosphate; Adult; Aged; Blood Pressure; Glycogen; Humans; Intermittent Claudication; Ischemia; Lactates; Lactic Acid; Leg; Middle Aged; Muscles; Oxygen Consumption; Phosphocreatine; Pyruvates; Pyruvic Acid; Regional Blood Flow | 1985 |
Cerebral energy metabolism during bicuculline-induced status epilepticus in spontaneously hypertensive rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bicuculline; Brain; Cerebrovascular Circulation; Energy Metabolism; Glycogen; Lactates; Lactic Acid; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Status Epilepticus; Time Factors | 1985 |
The relationship between exposure duration, carboxyhemoglobin, blood glucose, pyruvate and lactate and the severity of intoxication in 39 cases of acute carbon monoxide poisoning in man.
Topics: Adolescent; Adult; Aged; Blood Glucose; Carbon Monoxide Poisoning; Carboxyhemoglobin; Female; Hemoglobins; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1985 |
Regulation of food intake by hepatic oxidative metabolism.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Dihydroxyacetone; Eating; Glycerol; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Malates; Oxaloacetates; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1985 |
[Status of the pyruvate-LDH-lactate system in tissues of the vertebral bodies and intervertebral disks of the rat during hypokinesia in relation to age].
Topics: Age Factors; Animals; Intervertebral Disc; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Movement; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Spine | 1985 |
[Studies of muscle metabolism in chronic major limb arterial occlusive disease patients by unilateral ergometric lower leg stress (III)].
Topics: Adult; Aged; Arterial Occlusive Diseases; Chronic Disease; Energy Metabolism; Exercise Test; Humans; Lactates; Lactic Acid; Leg; Male; Middle Aged; Muscles; Pyruvates; Pyruvic Acid | 1985 |
The effect of age on glucose and energy metabolism in brain cortex of rats.
Topics: Adenosine Triphosphate; Aging; Animals; Cerebral Cortex; Citrates; Citric Acid; Energy Metabolism; Glucose; Ketoglutaric Acids; Lactates; Lactic Acid; Malates; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
The effect of exposure duration on the blood level of glucose, pyruvate and lactate in acute carbon monoxide intoxication in man.
Topics: Adolescent; Adult; Aged; Blood Glucose; Carbon Monoxide Poisoning; Carboxyhemoglobin; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1985 |
Mathematical model of muscular fatigue. II. Changes of metabolites level and of force during exercise in relation to a fatigability parameter.
Topics: Adenosine Triphosphate; Calcium; Computers; Energy Metabolism; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Models, Biological; Muscle Contraction; Muscles; Physical Exertion; Pyruvates; Pyruvic Acid; Time Factors | 1985 |
[Gas exchange and metabolic functions of the lungs in endotoxic shock].
Topics: Acidosis, Respiratory; Animals; Dogs; Female; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic Acid; Lung; Male; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid; Respiratory Distress Syndrome; Respiratory Insufficiency; Serotonin; Shock, Septic | 1985 |
Urea synthesis in hepatocytes isolated from young and old rats.
Topics: Aging; Ammonium Chloride; Animals; Epinephrine; Glucagon; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Ornithine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1985 |
Impaired hormonal stimulation in isolated hepatocytes of phosphorous depleted rats.
Topics: Animals; Cyclic AMP; Epinephrine; Glucagon; Gluconeogenesis; Insulin; Lactates; Lactic Acid; Liver; Male; Phosphorus; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
[Pituitary hormone responses to exercise at high altitudes].
Topics: Adrenocorticotropic Hormone; Adult; Altitude; Follicle Stimulating Hormone; Growth Hormone; Humans; Lactates; Lactic Acid; Luteinizing Hormone; Male; Middle Aged; Physical Exertion; Pituitary Hormones, Anterior; Prolactin; Pyruvates; Pyruvic Acid | 1984 |
Effects of ischemia on metabolite concentrations in dog renal cortex.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Female; Glutamates; Glutamic Acid; Hydroxybutyrates; Ischemia; Keto Acids; Ketoglutaric Acids; Kidney; Kidney Cortex; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats | 1982 |
Energy metabolism in cultured human fibroblasts during aging in vitro.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Division; Cell Line; Cell Survival; Citric Acid Cycle; Female; Fibroblasts; Glucose; Glutamates; Glutamic Acid; Glycolysis; Humans; Lactates; Lactic Acid; Male; Oxygen Consumption; Progeria; Pyruvates; Pyruvic Acid; Skin | 1982 |
Inhibition of hepatic lipogenesis by salicylate.
Topics: Acetyl-CoA Carboxylase; Animals; Cholesterol; Fatty Acids; Glucagon; In Vitro Techniques; Lactates; Lactic Acid; Lipids; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1982 |
The effects of fasting on glucose and 3-hydroxybutyrate utilization by the adult chick brain.
Topics: 3-Hydroxybutyric Acid; Acetyl-CoA C-Acetyltransferase; Acetyl-CoA C-Acyltransferase; Animals; Brain; Chickens; Fasting; Glucose; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Lactates; Lactic Acid; Mitochondria; Pyruvates; Pyruvic Acid | 1983 |
An improved method for perfusion of the isolated brain of the rat-influence of perfusion conditions and application of analeptic and anticonvulsant drugs.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain; Central Nervous System Stimulants; Lactates; Lactic Acid; Male; Pentylenetetrazole; Perfusion; Phenobarbital; Primidone; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Seizures | 1983 |
Gluconeogenesis in guinea pig renal tubule fragments--effects of noradrenaline, 3':5' cyclic AMP and angiotensin II.
Topics: Angiotensin II; Animals; Cyclic AMP; Gluconeogenesis; Glycerol; Guinea Pigs; Ketoglutaric Acids; Kidney Tubules; Lactates; Lactic Acid; Malates; Male; Norepinephrine; Pyruvates; Pyruvic Acid | 1983 |
Intermediary metabolism in Legionella pneumophila: utilization of amino acids and other compounds as energy sources.
Topics: Acetates; Amino Acids; Carboxylic Acids; Glucose; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Legionella; Oxygen Consumption; Pentosephosphates; Pyruvates; Pyruvic Acid; Serine; Threonine | 1983 |
Lactate, alanine and glutamine metabolism in isolated canine pup liver cells.
Topics: Alanine; Ammonia; Animals; Dogs; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1983 |
Changes of serum pyruvate and lactate in open-heart surgery.
Topics: Adolescent; Adult; Alanine Transaminase; Anesthesia, General; Aspartate Aminotransferases; Cardiac Surgical Procedures; Child; Child, Preschool; Extracorporeal Circulation; Female; gamma-Glutamyltransferase; Humans; Intraoperative Period; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Middle Aged; Postoperative Period; Pyruvates; Pyruvic Acid | 1984 |
The metabolic effects of dopamine in man.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Catecholamines; Dopamine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Hemodynamics; Humans; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Metabolism; Pyruvates; Pyruvic Acid; Somatostatin | 1984 |
Metabolic effects of adrenaline and noradrenaline in man: studies with somatostatin.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Norepinephrine; Pyruvates; Pyruvic Acid; Somatostatin | 1984 |
Effects of ethanol, fructose, and ethanol plus fructose infusions on plasma glucose concentration and glucose turnover in monkeys (Macaca fascicularis) as measured by [6-3H]glucose.
Topics: Animals; Blood Glucose; Ethanol; Female; Fructose; Kinetics; Lactates; Lactic Acid; Macaca fascicularis; Pyruvates; Pyruvic Acid; Time Factors; Tritium | 1984 |
The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis.
Topics: Alanine; Animals; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Lactates; Lactic Acid; Male; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Substrate Specificity | 1984 |
Diurnal metabolic profiles in hyperthyroidism.
Topics: Adult; Antithyroid Agents; Blood Glucose; Circadian Rhythm; Fatty Acids, Nonesterified; Female; Glycerol; Growth Hormone; Humans; Hyperthyroidism; Insulin; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Thyroid Hormones | 1982 |
Regulation of the salvage pathway of purine nucleotide synthesis by the oxidation state of NAD+ in rat heart cells.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Glycolysis; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Methylphenazonium Methosulfate; Myocardium; NAD; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Induced muscular work overload and disuse on the serum carbohydrate metabolism of dog, Canis domesticus.
Topics: Animals; Blood Glucose; Carbohydrates; Dogs; Electric Stimulation; Lactates; Lactic Acid; Male; Muscle Denervation; Muscular Atrophy; Physical Exertion; Pyruvates; Pyruvic Acid | 1983 |
Red cell metabolism affects lactate and pyruvate partition across the plasma membrane.
Topics: Cell Compartmentation; Culture Media; Erythrocyte Membrane; Erythrocytes; Glucose; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1983 |
Severe cerebral ischemia treatment by ventriculosubarachnoid perfusion with an oxygenated fluorocarbon emulsion.
Topics: Animals; Brain Ischemia; Carbon Dioxide; Cats; Cerebral Cortex; Cerebral Ventricles; Electroencephalography; Energy Metabolism; Evoked Potentials; Fluorocarbons; Lactates; Lactic Acid; Oxygen; Perfusion; Pyruvates; Pyruvic Acid; Subarachnoid Space | 1983 |
Fasting-induced impairment of glucose-1,6-bisphosphate synthesis in pancreatic islets.
Topics: Animals; Fasting; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glutamate Dehydrogenase; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; Phosphoglucomutase; Proteins; Pyruvates; Pyruvic Acid; Rats | 1984 |
Alcohol and the liver. Recent developments in preclinical and clinical research. Overview.
Topics: Adenosine Triphosphatases; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alcoholism; Animals; Ethanol; Fatty Liver, Alcoholic; Hepatitis, Alcoholic; Humans; Lactates; Lactic Acid; Liver; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1984 |
Effects of increased blood ammonia concentrations on the concentrations of some metabolites in rat tissues.
Topics: Adenosine Triphosphate; Ammonia; Animals; Cyclic AMP; Energy Metabolism; Glucose; Glycogen; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1981 |
Reversible inhibition of meiosis resumption in mouse dictyate oocytes by sub-optimal media.
Topics: Animals; Bucladesine; Cells, Cultured; Culture Media; Female; Glucose; Lactates; Lactic Acid; Meiosis; Mice; Oocytes; Ovum; Pyruvates; Pyruvic Acid | 1982 |
Effects of pyruvate on the growth of normal and transformed hamster embryo fibroblasts.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Glucose; Glutamine; Lactates; Lactic Acid; Polyomavirus; Pyruvates; Pyruvic Acid | 1982 |
Haemodynamics and myocardial metabolism of phosphorus depleted dogs: effects of catecholamines and angiotensin II.
Topics: Angiotensin II; Animals; Calcium; Catecholamines; Cyclic AMP; Dogs; Female; Hemodynamics; Lactates; Lactic Acid; Metaproterenol; Myocardium; Norepinephrine; Phosphorus; Phosphorus Metabolism Disorders; Pyruvates; Pyruvic Acid; Sarcoplasmic Reticulum | 1982 |
FSH stimulation of the production of pyruvate and lactate by rat Sertoli cells may be involved in hormonal regulation of spermatogenesis.
Topics: Age Factors; Animals; Bucladesine; Cells, Cultured; Follicle Stimulating Hormone; Insulin; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sertoli Cells; Spermatogenesis; Testosterone | 1983 |
Effects of FSH, isoproterenol, and cyclic AMP on the production of lactate and pyruvate by cultured Sertoli cells.
Topics: Animals; Cells, Cultured; Cyclic AMP; Follicle Stimulating Hormone; Isoproterenol; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Sertoli Cells | 1983 |
Catecholamine stimulation of hepatic gluconeogenesis at the site between pyruvate and phosphoenolpyruvate.
Topics: Aminooxyacetic Acid; Animals; Bucladesine; Gluconeogenesis; Guinea Pigs; Lactates; Lactic Acid; Liver; Malates; Norepinephrine; Oxaloacetates; Phosphoenolpyruvate; Picolinic Acids; Pyruvates; Pyruvic Acid; Rats | 1983 |
[Peculiarities of carbohydrate metabolism in the rat liver due to the limited accessibility of thiamine].
Topics: Adenine Nucleotides; Animals; Carbohydrate Metabolism; Cyclic AMP; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Thiamine Deficiency | 1983 |
Inhibition of lipogenesis by vasopressin and angiotensin II in glycogen-depleted hepatocytes.
Topics: Angiotensin II; Animals; Bucladesine; Citrates; Female; Glycogen; Lactates; Lactic Acid; Lipids; Liver; Proline; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Vasopressins | 1983 |
[Effects of dibutyryl cyclic AMP on myocardial metabolism].
Topics: Adult; Bucladesine; Female; Glucose; Humans; Lactates; Lactic Acid; Male; Middle Aged; Myocardium; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1983 |
Physical training of Zucker rats: lack of alleviation of muscle insulin resistance.
Topics: Animals; Blood Glucose; Glucose; Insulin; Insulin Resistance; Lactates; Lactic Acid; Muscles; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker; Receptor, Insulin | 1983 |
The effect of growth hormone on splanchnic glucose and substrate metabolism following oral glucose loading in healthy man.
Topics: Administration, Oral; Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid | 1984 |
The 75-g oral glucose tolerance test: effect on splanchnic metabolism of substrates and pancreatic hormone release in healthy man.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucagon; Glucose Tolerance Test; Hepatic Artery; Hepatic Veins; Humans; Insulin; Lactates; Lactic Acid; Liver Circulation; Male; Pancreatic Hormones; Pancreatic Polypeptide; Pyruvates; Pyruvic Acid; Splanchnic Circulation | 1983 |
Phenobarbital treatment enhances insulin mediated glucose metabolism in man.
Topics: Adult; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Lactates; Lactic Acid; Male; Metabolic Clearance Rate; Phenobarbital; Pyruvates; Pyruvic Acid | 1984 |
[Insulin extraction by the isolated perfused rat liver using infusion conditions of a biphasic insulin concentration profile].
Topics: Animals; Erythrocytes; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Insulin Infusion Systems; Lactates; Lactic Acid; Liver; Pancreas; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Lidocaine therapy in awake endotoxemic Yucatan minipigs. I. Metabolic parameters and glucose biokinetics.
Topics: Acid-Base Equilibrium; Animals; Blood Glucose; Blood Pressure; Electrolytes; Endotoxins; Energy Metabolism; Escherichia coli; Female; Insulin; Kinetics; Lactates; Lactic Acid; Lidocaine; Oxygen; Pyruvates; Pyruvic Acid; Swine; Swine, Miniature | 1984 |
Lidocaine therapy in awake endotoxemic Yucatan minipigs. II. Hepatosplanchnic metabolism.
Topics: Animals; Blood Flow Velocity; Blood Glucose; Endotoxins; Escherichia coli; Female; Kinetics; Lactates; Lactic Acid; Lidocaine; Liver; Liver Circulation; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Splanchnic Circulation; Swine; Swine, Miniature | 1984 |
Hepatic and systemic metabolic responses to aerobic and anaerobic intra-abdominal abscesses in a highly reproducible chronic rat model.
Topics: Abdomen; Abscess; Acidosis; Adenine Nucleotides; Animals; Bacteroides fragilis; Bacteroides Infections; Blood Glucose; Body Weight; Energy Metabolism; Escherichia coli Infections; Fever; Lactates; Lactic Acid; Leukocyte Count; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Metabolism during hepatic transplantation: indicators of allograft function.
Topics: Adult; Amino Acids; Aspartate Aminotransferases; Bilirubin; Child; Child, Preschool; Female; Humans; Infant; Intraoperative Period; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Liver Circulation; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Perfusion; Pyruvates; Pyruvic Acid | 1984 |
Evidence that changes in hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity are required partly to maintain a constant rate of sterol synthesis.
Topics: Animals; Glycogen; Hydroxymethylglutaryl CoA Reductases; In Vitro Techniques; Insulin; Kinetics; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sterols | 1984 |
The response of blood intermediary metabolite levels to 24 hours treatment with a blood glucose-controlled insulin infusion system in type 1 diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Diabetes Mellitus, Type 1; Female; Glycerol; Humans; Hydroxybutyrates; Insulin; Insulin Infusion Systems; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1984 |
Effects of dichloroacetate on the lactate/pyruvate ratio and on aspartate and leucine metabolism in cultured rat skeletal muscle cells.
Topics: Acetates; Animals; Aspartic Acid; Carbon Dioxide; Cells, Cultured; Culture Media; Dichloroacetic Acid; Lactates; Lactic Acid; Leucine; Male; Muscles; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Combined effect of lysine and acetate on gluconeogenesis from lactate in isolated hepatocytes.
Topics: Acetates; Animals; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Liver; Lysine; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Metabolic compartmentation of pyruvate in the isolated perfused rat heart.
Topics: Alanine; Animals; Carbon Dioxide; Cell Compartmentation; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Male; Mitochondria, Heart; Models, Biological; Myocardium; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Effect of gossypol on the motility and metabolism of human spermatozoa.
Topics: Adenosine Triphosphate; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Fructose; Glucose; Gossypol; Humans; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sperm Motility; Spermatozoa; Vagina | 1983 |
[Ophthalmoplegia plus. On nosologic, biochemical, morphologic and computer tomographic aspects of the oculocraniosomatic syndrome].
Topics: Adult; Biopsy; Blepharoptosis; Brain Stem; Enzymes; Humans; Lactates; Lactic Acid; Male; Muscles; Neuromuscular Diseases; Ophthalmoplegia; Pyruvates; Pyruvic Acid; Syndrome; Tomography, X-Ray Computed | 1983 |
Effect of treadmill exercise on blood gases and acid-base balance in patients with intermittent claudication.
Topics: Acid-Base Equilibrium; Adult; Aged; Bicarbonates; Carbon Dioxide; Exercise Test; Female; Hemodynamics; Humans; Hydrogen-Ion Concentration; Intermittent Claudication; Lactates; Lactic Acid; Male; Middle Aged; Oxygen; Partial Pressure; Pyruvates; Pyruvic Acid; Respiration | 1983 |
Hormone and metabolite profiles in alcoholic liver disease.
Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Female; Food; Glycerol; Growth Hormone; Humans; Hydrocortisone; Insulin; Lactates; Lactic Acid; Lipid Metabolism; Liver Cirrhosis, Alcoholic; Liver Diseases, Alcoholic; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1983 |
Decrease of flux through pyruvate dehydrogenase and branched-chain 2-oxo-acid dehydrogenase by nitrofurantoin in perfused rat liver.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Carbon Dioxide; Glucose; In Vitro Techniques; Ketone Oxidoreductases; Lactates; Lactic Acid; Liver; Male; Multienzyme Complexes; Nitrofurantoin; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
[Glucose, lactate, and pyruvate consumption of the myocardium in German Landrace and crossed German Landrace and wild swine (F1 and F2)].
Topics: Animals; Animals, Wild; Crosses, Genetic; Female; Glucose; Lactates; Lactic Acid; Male; Myocardium; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Swine | 1983 |
[Effect of therapeutic hyperventilation on blood lactate concentration].
Topics: Adult; Aged; Brain Injuries; Carbon Dioxide; Child; Child, Preschool; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Respiration, Artificial; Respiratory Therapy | 1983 |
Effect of ethanol and metabolic substrates on the oxidation of aminopyrine, formaldehyde and formate by isolated hepatocytes.
Topics: Aminopyrine; Animals; Carbon Dioxide; Cells, Cultured; Ethanol; Formaldehyde; Formates; Fructose; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol; Xylitol | 1983 |
Different effects of interventions suppressing free fatty acid metabolism on myocardial ischemia.
Topics: Animals; Coronary Disease; Dichloroacetic Acid; Dogs; Fatty Acids, Nonesterified; Glucose; Hemodynamics; Infusions, Parenteral; Insulin; Lactates; Lactic Acid; Mannitol; Myocardium; Potassium; Pyruvates; Pyruvic Acid | 1984 |
The effects of metformin compared to the effects of phenformin on the lactate production and the metabolism of isolated parenchymal rat liver cell.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Ethanol; Glycerol; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Liver; Male; Metformin; Oxygen Consumption; Phenformin; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Metabolism of round spermatids: evidence that lactate is preferred substrate.
Topics: Adenine Nucleotides; Animals; Carbon Dioxide; Carbon Radioisotopes; Glucose; Glycolysis; Kinetics; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Spermatids; Spermatozoa | 1984 |
Blood acetaldehyde concentration gradient between hepatic and antecubital venous blood in ethanol-intoxicated alcoholics and controls.
Topics: Acetaldehyde; Adult; Alcoholic Intoxication; Alcoholism; Ethanol; Humans; Kinetics; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1984 |
Lactic acidaemia.
Topics: Abnormalities, Multiple; Child; Humans; Lactates; Lactic Acid; Metabolism, Inborn Errors; Pyruvate Carboxylase Deficiency Disease; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid | 1984 |
Central hypoventilation syndrome in pyruvate dehydrogenase complex deficiency.
Topics: Almitrine; Cells, Cultured; Chemoreceptor Cells; Child; Decarboxylation; Doxapram; Fibroblasts; Humans; Lactates; Lactic Acid; Male; Piperazines; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Respiration, Artificial; Sleep Apnea Syndromes; Tracheotomy | 1984 |
Defects in citric acid cycle and the electron transport chain in progressive poliodystrophy.
Topics: Adolescent; Brain; Carbon Dioxide; Child; Child, Preschool; Citric Acid Cycle; Electron Transport; Fibroblasts; Humans; Lactates; Lactic Acid; Leukocytes; Liver; Muscle Hypotonia; Muscle Spasticity; NADH Dehydrogenase; Neuromuscular Diseases; Paralysis; Psychomotor Disorders; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid | 1984 |
Biochemical studies on pulmonary candidiasis in guinea pigs.
Topics: Animals; Candidiasis; Collagen; Glycosaminoglycans; Guinea Pigs; Lactates; Lactic Acid; Lung; Lung Diseases, Fungal; Male; Pyruvates; Pyruvic Acid | 1981 |
Effect of hyperthyroidism on hepatic lipogenesis in rats: studies in vivo and in vitro.
Topics: Animals; Female; Hyperthyroidism; In Vitro Techniques; Lactates; Lactic Acid; Lipids; Liver; Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Triiodothyronine | 1984 |
Changes in blood glucose levels in relation to blood ketone body ratio following hypertonic glucose infusion in 70% hepatectomized rabbits.
Topics: Alanine; Animals; Bilirubin; Blood Glucose; Cholestasis; Citric Acid Cycle; Glucose; Glucose Solution, Hypertonic; Hepatectomy; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Postoperative Complications; Postoperative Period; Pyruvates; Pyruvic Acid; Rabbits; Time Factors | 1984 |
The effect of ketone bodies and fatty acid on intestinal glucose metabolism during development.
Topics: 3-Hydroxybutyric Acid; Animal Population Groups; Animals; Animals, Suckling; Fatty Acids; Female; Glucose; Hydroxybutyrates; Intestinal Mucosa; Ketone Bodies; Lactates; Lactic Acid; Male; NAD; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats | 1984 |
Influence of oleate oxidation on pyruvate production and utilization in hepatocytes isolated from fed rats. Effect of 2-[5-(4-chlorophenyl)pentyl]oxiran-2-carboxylate.
Topics: Animals; Epoxy Compounds; Ethers, Cyclic; Glycolysis; Hypoglycemic Agents; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Protection of hypoxic myocardium by intracoronary administration of verapamil in open-chest dogs.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dogs; Energy Metabolism; Hemodynamics; Lactates; Lactic Acid; Myocardial Contraction; Myocardial Infarction; Myocardium; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Verapamil | 1984 |
[Effect of calcium, lanthanum and neodymium ions on the permeability of the corneal epithelium to low molecular metabolites in animals].
Topics: Animals; Blood Glucose; Calcium; Cell Membrane Permeability; Cornea; Epithelium; Lactates; Lactic Acid; Lanthanum; Neodymium; Pyruvates; Pyruvic Acid; Rabbits | 1984 |
The relationship between glucose concentration and rate of lactate production by human erythrocytes in an open perfusion system.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Glucose; Diphosphoglyceric Acids; Erythrocytes; Glycolysis; Hexokinase; Humans; Kinetics; Lactates; Lactic Acid; Mathematics; Perfusion; Pyruvates; Pyruvic Acid | 1984 |
Biochemical observations on a non-elite marathon runner.
Topics: Adult; Amino Acids; Blood Cell Count; Blood Glucose; Body Weight; Creatine Kinase; Electrocardiography; Electrolytes; Humans; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Running; Time Factors | 1984 |
Effect of an extract of Ginkgo biloba on rat brain energy metabolism in hypoxia.
Topics: Animals; Brain; Energy Metabolism; Hypoxia; Lactates; Lactic Acid; Male; Plant Extracts; Plants, Medicinal; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Effects of dichloroacetate on pyruvate metabolism in rat brain in vivo.
Topics: Acetates; Animals; Blood Glucose; Brain; Dichloroacetic Acid; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Lactates; Lactic Acid; Liver; Male; Muscles; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Uterine blood flow and substrate uptake in conscious rabbit during late gestation.
Topics: Animals; Blood Glucose; Consciousness; Fatty Acids, Nonesterified; Female; Ketone Bodies; Lactates; Lactic Acid; Maternal-Fetal Exchange; Oxygen; Oxygen Consumption; Pregnancy; Pregnancy, Animal; Pyruvates; Pyruvic Acid; Rabbits; Regional Blood Flow; Uterus | 1984 |
[Effect of physical exertion on heart muscle metabolism in disorders of thyroid function].
Topics: Animals; Citrates; Citric Acid; Female; Glycogen; Lactates; Lactic Acid; Lipid Metabolism; Male; Myocardium; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Changes in metabolism of the rumen bacterium Streptococcus bovis H13/1 resulting from alteration in dilution rate and glucose supply per unit time.
Topics: Acetates; Acetic Acid; Animals; Bacteria; Culture Media; Fermentation; Glucose; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rumen; Streptococcus | 1984 |
Stimulation of glycogenolysis and platelet-activating factor production by heat-aggregated immunoglobulin G in the perfused rat liver.
Topics: Animals; Hot Temperature; Immunoglobulin G; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; NAD; Oxygen Consumption; Perfusion; Platelet Activating Factor; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Stimulation of cardiac contractility by catecholamines is diminished in experimental uremia.
Topics: Angiotensin II; Animals; Catecholamines; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Hemodynamics; Lactates; Lactic Acid; Metaproterenol; Myocardial Contraction; Pyruvates; Pyruvic Acid; Uremia | 1984 |
Gluconeogenesis, cytosolic redox potential, and phosphate and fluid transport in the isolated rabbit proximal tubule.
Topics: Animals; Antimetabolites; Body Fluids; Cytosol; Gluconeogenesis; Glucose; Hydrogen-Ion Concentration; In Vitro Techniques; Ketoglutaric Acids; Kidney Tubules, Proximal; Lactates; Lactic Acid; Methylene Blue; Oxidation-Reduction; Phosphates; Picolinic Acids; Pyruvates; Pyruvic Acid; Rabbits | 1984 |
[Adaptive changes in carbohydrate metabolism in the placenta in experimental fetal anoxia].
Topics: Animals; Female; Fetal Hypoxia; Glucose; Lactates; Lactic Acid; Placenta; Pregnancy; Pyruvates; Pyruvic Acid; Rabbits | 1984 |
Pulmonary hemorrhage in experimental cerebral ischemia in mongolian gerbils. Brain metabolism and lung pathology.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain; Brain Ischemia; Female; Gerbillinae; Hemorrhage; Lactates; Lactic Acid; Lung; Lung Diseases; Male; Pulmonary Edema; Pyruvates; Pyruvic Acid | 1984 |
Effect of lactate and pyruvate on cerebrocortical microcirculation and NAD/NADH redox state.
Topics: Animals; Cats; Cerebral Cortex; Cerebrovascular Circulation; Lactates; Lactic Acid; Microcirculation; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1984 |
Cerebral metabolic and circulatory effects of 1,1,1-trichloroethane, a neurotoxic industrial solvent. 2. Tissue concentrations of labile phosphates, glycolytic metabolites, citric acid cycle intermediates, amino acids, and cyclic nucleotides.
Topics: Animals; Brain; Cerebrovascular Circulation; Citrates; Citric Acid; Glucose; Glycolysis; Hydrocarbons, Chlorinated; Lactates; Lactic Acid; Male; Neurotoxins; Nucleosides; Osmolar Concentration; Phosphates; Purine Nucleotides; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Solvents; Trichloroethanes | 1984 |
Familial intermittent ataxia with possible X-linked recessive inheritance. Two patients with abnormal pyruvate metabolism and a response to acetazolamide.
Topics: Acetazolamide; Adolescent; Adult; Ataxia; Female; Genes, Recessive; Humans; Lactates; Lactic Acid; Male; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Syndrome; X Chromosome | 1984 |
Pyruvate metabolism in the brain of young rats intoxicated with organic and inorganic lead.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Dihydrolipoamide Dehydrogenase; Lactates; Lactic Acid; Lead; Organometallic Compounds; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Tetraethyl Lead | 1984 |
The effect of monoacetin and calcium chloride on acid-base balance and survival in experimental sodium fluoroacetate poisoning.
Topics: Acid-Base Imbalance; Animals; Antidotes; Blood Pressure; Calcium; Calcium Chloride; Cats; Fluoroacetates; Glycerides; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Time Factors | 1983 |
Requirement for alanine in the amino acid control of deprivation-induced protein degradation in liver.
Topics: Alanine; Amino Acids; Animals; Caprylates; Lactates; Lactic Acid; Liver; Male; Proteins; Pyruvates; Pyruvic Acid; Rats; Starvation | 1984 |
L-amino acids from a racemic mixture of alpha-hydroxy acids.
Topics: Alanine; Alanine Dehydrogenase; Amino Acid Oxidoreductases; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Pyruvates; Pyruvic Acid; Stereoisomerism | 1984 |
Enzymatic synthesis of [1-11C]pyruvic acid, L-[1-11C]lactic acid and L-[1-11C]alanine via DL-[1-11C]alanine.
Topics: Alanine; Carbon Radioisotopes; Enzymes, Immobilized; Isotope Labeling; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Tomography, Emission-Computed | 1984 |
Nature of Na+-independent stimulation of renal transport of p-aminohippurate by exogenous metabolites.
Topics: Acetates; Aerobiosis; Aminohippuric Acids; Anaerobiosis; Animals; Biological Transport; Female; In Vitro Techniques; Kidney; Kinetics; Lactates; Lactic Acid; Male; Ouabain; p-Aminohippuric Acid; Pyruvates; Pyruvic Acid; Rabbits; Sodium; Sodium Fluoride | 1983 |
Effects of physiologic concentrations of lactate, pyruvate and ascorbate on glucose metabolism in unstressed and oxidatively stressed human red blood cells.
Topics: Adult; Aerobiosis; Ascorbic Acid; Blood Glucose; Carbon Radioisotopes; Erythrocytes; Glycolysis; Humans; Kinetics; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1983 |
A simplified method for the estimation of individual amino acid radioactivity in plasma samples.
Topics: Amino Acids; Animals; Blood Glucose; Chromatography, Thin Layer; Glycerol; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rats | 1983 |
Enhancement of the stimulating effect of fructose-1.6-diphosphate on the metabolic energy balance of carbohydrate-deficient bovine lenses by additional supply with ADP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Cattle; Energy Metabolism; Fructosediphosphates; Glycolysis; Hexosediphosphates; Lactates; Lactic Acid; Lens, Crystalline; Pyruvates; Pyruvic Acid | 1983 |
Factors influencing rates of ethanol oxidation in isolated rat hepatocytes.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Cytosol; Ethanol; Fructose; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Biochemical mode of action of a hepatoprotective drug: observations on (+)-catechin.
Topics: Animals; Benzopyrans; Catechin; Ethanol; Fatty Liver, Alcoholic; Glutamate Dehydrogenase; Lactates; Lactic Acid; Lipid Metabolism; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Triglycerides | 1983 |
Lactate production in a pure red muscle in absence of anoxia: mechanisms and significance.
Topics: Animals; Dogs; Glycolysis; Hypoxia; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Mitochondria, Muscle; Muscles; Myoglobin; Oxygen Consumption; Pyruvates; Pyruvic Acid; Regional Blood Flow | 1983 |
Splanchnic glucose metabolism during leg exercise in 60-hour-fasted human subjects.
Topics: Adult; Alanine; Blood Glucose; Fasting; Fatty Acids, Nonesterified; Glucose; Glycerol; Humans; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Liver; Male; Physical Exertion; Pyruvates; Pyruvic Acid; Splanchnic Circulation | 1983 |
The effects of ingested and intravenous glucose on forearm uptake of glucose and glucogenic substrate in normal man.
Topics: Administration, Oral; Adult; Blood Glucose; Female; Forearm; Gluconeogenesis; Glucose; Humans; Infusions, Parenteral; Lactates; Lactic Acid; Liver Glycogen; Male; Pyruvates; Pyruvic Acid | 1983 |
Control of gluconeogenesis in rat liver cells. I. Kinetics of the individual enzymes and the effect of glucagon.
Topics: Animals; Glucagon; Gluconeogenesis; Glucose-6-Phosphate; Glucosephosphates; Kinetics; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Comparison of the kinetics and utilisation of D(-)-and L(+)-sodium lactate in normal man.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Alanine; Female; Humans; Hydroxybutyrates; Kinetics; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Stereoisomerism | 1983 |
Effects of fenfluramine on hepatic intermediary metabolism.
Topics: Acetyl Coenzyme A; Alanine; Animals; Fatty Acids; Fenfluramine; Gluconeogenesis; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
[Changes of the acid-base status, serum lactate concentration and purine metabolism in reconstructive arterial surgery].
Topics: Acid-Base Equilibrium; Adenosine; Aorta, Abdominal; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Middle Aged; Purines; Pyruvates; Pyruvic Acid; Uric Acid; Xanthine; Xanthines | 1983 |
The role of mitochondrial pyruvate transport in the control of lactate gluconeogenesis.
Topics: Animals; Bicarbonates; Biological Transport, Active; Coumaric Acids; Cytosol; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats | 1983 |
Effect of pyridoxine alpha-ketoglutarate (PAK) on ammonia and pyruvic and lactic acid blood levels in patients with cirrhosis.
Topics: Aged; Amino Acids; Ammonia; Blood Glucose; Double-Blind Method; Drug Evaluation; Female; Humans; Lactates; Lactic Acid; Liver Cirrhosis; Male; Middle Aged; Pyridoxine; Pyruvates; Pyruvic Acid; Random Allocation | 1983 |
Lactic acid concentrations in vitreous humor: their use in asphyxial deaths in children.
Topics: Asphyxia; Blood Glucose; Child, Preschool; Forensic Medicine; Humans; Infant; Infant, Newborn; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Stress, Physiological; Sudden Infant Death; Vitreous Body | 1983 |
Zonal redox changes as a cause of selective perivenular hepatotoxicity of alcohol.
Topics: Alcoholism; Animals; Ethanol; Fatty Liver, Alcoholic; Hepatic Veins; Humans; Lactates; Lactic Acid; Liver; Liver Cirrhosis, Alcoholic; Oxidation-Reduction; Oxygen; Oxygen Consumption; Papio; Proteins; Pyruvates; Pyruvic Acid | 1983 |
Concentrations of lactate and pyruvate in maternal and neonatal blood with different intravenous fluids used for prehydration before epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Blood Glucose; Cesarean Section; Female; Fetal Blood; Fluid Therapy; Gluconates; Humans; Infant, Newborn; Isotonic Solutions; Lactates; Lactic Acid; Magnesium Chloride; Potassium Chloride; Pregnancy; Preoperative Care; Pyruvates; Pyruvic Acid; Ringer's Lactate; Sodium Acetate; Sodium Chloride | 1984 |
Kinetic characterization of the lactate dehydrogenase (LDH-B4) allozymes of Fundulus heteroclitus.
Topics: Alleles; Animals; Fishes; Hydrogen-Ion Concentration; Isoenzymes; Killifishes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Temperature | 1984 |
Transfer and metabolism of norepinephrine studied from maternal-to-fetal and fetal-to-maternal sides in the in vitro perfused human placental lobe.
Topics: Antipyrine; Clorgyline; Female; Glucose; Humans; In Vitro Techniques; Lactates; Lactic Acid; Mandelic Acids; Maternal-Fetal Exchange; Norepinephrine; Placenta; Pregnancy; Pyruvates; Pyruvic Acid; Vanilmandelic Acid | 1984 |
[Oxygen and hemodynamic provisions for measured physical exertion in ischemic heart disease patients with intact and atherosclerotic coronary arteries].
Topics: Adult; Coronary Disease; Exercise Test; Hemodynamics; Humans; Lactates; Lactic Acid; Middle Aged; Myocardial Infarction; Physical Exertion; Pyruvates; Pyruvic Acid; Respiration | 1984 |
[Lactic and pyruvic acid levels and lactate dehydrogenase activity in the blood in stroke].
Topics: Adult; Aged; Cerebrovascular Disorders; Female; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1984 |
Inhibition of mixed-function oxidation in perfused rat liver by fluoroacetate treatment.
Topics: Animals; Citrates; Citric Acid; Female; Fluoroacetates; Glucose; Lactates; Lactic Acid; Liver; Mixed Function Oxygenases; Nitroanisole O-Demethylase; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Effect of glucose and pyruvate metabolism on membrane potential in synaptosomes.
Topics: Animals; Brain; Coloring Agents; Glucose; Intracellular Membranes; Kinetics; Lactates; Lactic Acid; Membrane Potentials; Pyruvates; Pyruvic Acid; Rats; Rhodamines; Synaptosomes | 1984 |
The kinetic mechanism of pyruvate reduction by lactate dehydrogenase from Phycomyces blakesleeanus.
Topics: Fungi; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Phycomyces; Pyruvates; Pyruvic Acid | 1984 |
Aerobic glycolysis by the pituitary gland in vivo.
Topics: Aerobiosis; Animals; Blood Glucose; Cerebral Cortex; Fasting; Female; Glycolysis; Kinetics; Lactates; Lactic Acid; Pituitary Gland; Pyruvates; Pyruvic Acid; Swine | 1984 |
[Acid-base equilibrium, blood lactic acid and pyruvic acid in albino rats after muscular exertion under conditions of normal oxygen, hypoxia and hypoxia-hypercapnia].
Topics: Acid-Base Equilibrium; Animals; Hypercapnia; Hypoxia; Lactates; Lactic Acid; Male; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Proline and hepatic lipogenesis.
Topics: Animals; Citrates; Fatty Acids; Female; Lactates; Lactic Acid; Lipids; Liver; Picolinic Acids; Proline; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation | 1984 |
Lactate and regulation of lung glycolytic rate.
Topics: Animals; Glycolysis; Hypoxia; Kinetics; Lactates; Lactic Acid; Lung; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
Development of gluconeogenesis from dihydroxyacetone in rat hepatocytes during a feeding cycle and starvation.
Topics: Animals; Dihydroxyacetone; Food; Gluconeogenesis; Glucose; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Trioses | 1984 |
Lactate and pyruvate production in isolated thiamine-deficient rat diaphragm strips.
Topics: Animals; Diaphragm; Fatigue; Glucose; Glycolysis; Hydrogen; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Thiamine Deficiency | 1984 |
Nutritional factors affecting the synthesis of an antiphagocytic factor by group E streptococci.
Topics: Animals; Bacterial Proteins; Blood Proteins; Carbohydrate Metabolism; Citrates; Citric Acid; Culture Media; Lactates; Lactic Acid; Leukocytes; Phagocytosis; Pyruvates; Pyruvic Acid; Serum Albumin, Bovine; Streptococcus; Swine | 1984 |
3-Aminopicolinate inhibits phosphoenolpyruvate carboxykinase in hepatocytes and increases release of gluconeogenic precursors from peripheral tissues.
Topics: Animals; Blood Glucose; Gluconeogenesis; Glutamine; Kidney; Lactates; Lactic Acid; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinates | 1984 |
[Status of several types of tissue metabolism at rest and during functional tests in patients in the initial stage of heart failure].
Topics: Acid-Base Equilibrium; Adult; Aged; Exercise Test; Female; Glycolysis; Heart Failure; Humans; Lactates; Lactic Acid; Male; Middle Aged; Oxygen; Oxygen Consumption; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Sugar Phosphates | 1984 |
Glucose metabolism of oxidatively stressed human red blood cells incubated in plasma or medium containing physiologic concentrations of lactate, pyruvate and ascorbate.
Topics: Adenosine Triphosphate; Ascorbic Acid; Blood Glucose; Erythrocytes; Glycolysis; Humans; In Vitro Techniques; Lactates; Lactic Acid; Methemoglobin; Naphthoquinones; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1984 |
The stimulation of hepatic gluconeogenesis by acetoacetate precursors. A role for the monocarboxylate translocator.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetoacetates; Alanine; Animals; Gluconeogenesis; Hydroxybutyrates; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
[Stroma-free hemoglobin solution and perfusion of isolated extremities].
Topics: Adenosine Triphosphate; Animals; Blood Substitutes; Dogs; Extremities; Female; Hemoglobins; Lactates; Lactic Acid; Male; Muscles; Oxygen; Partial Pressure; Perfusion; Phosphocreatine; Pyruvates; Pyruvic Acid | 1984 |
The contribution of both extracellular and intracellular calcium to the action of alpha-adrenergic agonists in perfused rat liver.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Calcium; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Oxidation-Reduction; Oxygen Consumption; Perfusion; Phenylephrine; Potassium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
The effect of glyceraldehyde on red cells. Haemoglobin status, oxidative metabolism and glycolysis.
Topics: Blood Glucose; Erythrocytes; Glutathione; Glyceraldehyde; Glycolysis; Hemoglobins; Hexosephosphates; Humans; Lactates; Lactic Acid; Lactoylglutathione Lyase; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Thiolester Hydrolases | 1984 |
The metabolic and hormonal response to acute normoglycaemia in type 1 (insulin-dependent) diabetes: studies with a glucose controlled insulin infusion system (artificial endocrine pancreas).
Topics: Adult; Alanine; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Humans; Insulin; Insulin Infusion Systems; Ketone Bodies; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1982 |
Intravenous glucose tolerance test in childhood obesity: metabolite levels and their relation to glucose utilization rate (KG).
Topics: Blood Glucose; Body Height; Child; Cholesterol; Fasting; Fatty Acids, Nonesterified; Glucose Tolerance Test; Glycerol; Humans; Insulin; Lactates; Lactic Acid; Obesity; Pyruvates; Pyruvic Acid; Triglycerides | 1982 |
Effect of glucagon infusion on some plasma metabolites and hormones in obese children.
Topics: Amino Acids; Blood Glucose; Child; Cholesterol; Fatty Acids, Nonesterified; Glucagon; Glycerol; Growth Hormone; Humans; Insulin; Insulin Secretion; Lactates; Lactic Acid; Obesity; Pyruvates; Pyruvic Acid; Stimulation, Chemical; Triglycerides | 1982 |
Acute effect of ethanol on metabolite concentrations of dog pancreas in vivo.
Topics: Amino Acids; Animals; Dogs; Ethanol; Female; Lactates; Lactic Acid; Male; NAD; Pancreas; Pyruvates; Pyruvic Acid | 1982 |
Lactic acidosis due to pyruvate carboxylase deficiency.
Topics: Acidosis; Humans; Infant; Lactates; Lactic Acid; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Carboxylase Deficiency Disease; Pyruvates; Pyruvic Acid; Skin | 1981 |
Screening of high risk infants for metabolic disease in a metropolitan hospital.
Topics: Amino Acids; Ammonia; Carboxylic Acids; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lactates; Lactic Acid; Metabolism, Inborn Errors; Methylmalonic Acid; Pyruvates; Pyruvic Acid | 1981 |
A patient with pyruvate carboxylase deficiency in the liver: treatment with aspartic acid and thiamine.
Topics: Aspartic Acid; Child; Female; Humans; Lactates; Lactic Acid; Liver; Psychological Tests; Pyruvate Carboxylase Deficiency Disease; Pyruvates; Pyruvic Acid; Thiamine | 1981 |
The metabolism of the preserved heart. I. Does lactate properly reflect the functional state of the preserved heart? Part one.
Topics: Amino Acids; Animals; Fatty Acids, Nonesterified; Heart; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Organ Preservation; Perfusion; Pyruvates; Pyruvic Acid; Time Factors; Tissue Preservation | 1981 |
Myocardial protection during aortic valve replacement. effects of mannitol in the cardioplegic solution on cardiac metabolism and enzyme release.
Topics: Aortic Valve; Blood Glucose; Creatine Kinase; Heart Arrest, Induced; Heart Valve Prosthesis; Humans; Isoenzymes; Lactates; Lactic Acid; Mannitol; Myocardium; Myoglobin; Potassium; Pyruvates; Pyruvic Acid | 1981 |
Human skeletal muscle metabolism and morphology after temporary incomplete ischaemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adult; Aged; Constriction; Female; Humans; Intermittent Claudication; Ischemia; Lactates; Lactic Acid; Leg; Male; Middle Aged; Mitochondria, Muscle; Muscles; Phosphocreatine; Pyruvates; Pyruvic Acid | 1982 |
Blood:bone disequilibrium. VI. Studies of the solubility characteristics of brushite: apatite mixtures and their stabilization by noncollagenous proteins of bone.
Topics: Animals; Apatites; Blood Physiological Phenomena; Bone and Bones; Bone Matrix; Calcium Phosphates; Homeostasis; Hydrogen-Ion Concentration; Hydrolysis; Lactates; Lactic Acid; Proteins; Pyruvates; Pyruvic Acid; Rats; Sheep; Solubility | 1982 |
Carbon balance studies of glucose metabolism in rat cerebral cortical synaptosomes.
Topics: Amino Acids; Animals; Carbon Dioxide; Carbon Radioisotopes; Cerebral Cortex; Citric Acid Cycle; Glucose; Lactates; Lactic Acid; Male; Pentosephosphates; Psychotropic Drugs; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Synaptosomes | 1982 |
An attempt to establish metabolic indices useful in evaluating the training of thoroughbred racehorses.
Topics: Animals; Blood Sedimentation; Horses; Lactates; Lactic Acid; Male; Physical Exertion; Pyruvates; Pyruvic Acid; Sports | 1981 |
Influence of age upon the cerebral metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Topics: Adenine Nucleotides; Aging; Animals; Dihydroergotoxine; Dogs; Female; Hypoxia; Lactates; Lactic Acid; Motor Cortex; Phenobarbital; Phosphocreatine; Pyruvates; Pyruvic Acid; Synaptosomes; Vinca Alkaloids | 1982 |
Rates of flux through the pentose cycle in perfused rat liver. A procedure for the calculation of rates of substrate flux from 14CO2 production from [1-14C]glucose.
Topics: Animals; Carbon Dioxide; Glucose; Glucosephosphates; Kinetics; Lactates; Lactic Acid; Liver; Male; Pentoses; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
Determination of pyruvate dehydrogenase in cultured human fibroblasts and amniotic fluid cells.
Topics: Adenosine Triphosphate; Amniotic Fluid; Cells, Cultured; Egtazic Acid; Fibroblasts; Humans; Kinetics; Lactates; Lactic Acid; Methods; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid | 1982 |
Effects of severe arterial hypocapnia on regional blood flow regulation, tissue PO2 and metabolism in the brain cortex of cats.
Topics: Adenine Nucleotides; Animals; Carbon Dioxide; Cats; Cerebral Cortex; Cerebrovascular Circulation; Glucose; Hyperventilation; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Phosphocreatine; Pyruvates; Pyruvic Acid; Vascular Resistance | 1981 |
Buffer metabolism in continuous ambulatory peritoneal dialysis (CAPD): relationship with respiratory dynamics.
Topics: Acetates; Acid-Base Equilibrium; Adult; Buffers; Carbon Dioxide; Citric Acid Cycle; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Pyruvates; Pyruvic Acid; Respiration | 1982 |
Calculation of the rate of gluconeogenesis from the incorporation of 14C atoms from labelled bicarbonate or acetate.
Topics: Acetates; Animals; Bicarbonates; Carbon Dioxide; Carbon Radioisotopes; Dogs; Gluconeogenesis; Glucose; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Urea | 1982 |
Brown adipose tissue metabolism in hypothalamic-obese rats.
Topics: Adipose Tissue, Brown; Aging; Animals; Diet; Fatty Acids; Glucose; Hypothalamus; Lactates; Lactic Acid; Lipids; Male; Obesity; Pyruvates; Pyruvic Acid; Rats | 1983 |
Cerebral metabolism of amino acids and glucose in fed and fasted sheep.
Topics: Amino Acids; Animals; Brain; Cerebrovascular Circulation; Fasting; Female; Glucose; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Male; Oxygen Consumption; Pyruvates; Pyruvic Acid; Sheep | 1983 |
Glucose transport and metabolism in cultured human skin fibroblasts.
Topics: Biological Transport; Cells, Cultured; Culture Media; Fibroblasts; Glucose; Glycolysis; Humans; Lactates; Lactic Acid; Oxygen Consumption; Pyruvates; Pyruvic Acid; Skin | 1983 |
Compartmentation of fatty acid oxidation in liver cells.
Topics: Acetoacetates; Animals; Caproates; Cell Compartmentation; Fatty Acids; Lactates; Lactic Acid; Liver; Palmitic Acid; Palmitic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Rotenone | 1983 |
Interactions between alpha-ketoisovalerate metabolism and the pathways of gluconeogenesis and urea synthesis in isolated hepatocytes.
Topics: Ammonia; Animals; Citrulline; Gluconeogenesis; Hemiterpenes; In Vitro Techniques; Keto Acids; Kinetics; Lactates; Lactic Acid; Liver; Male; Myocardium; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Swine; Urea | 1983 |
J10 lactate-induced polycythemia in newts.
Topics: Alkalosis; Animals; Erythrocyte Count; Lactates; Lactic Acid; Polycythemia; Pyruvates; Pyruvic Acid; Salamandridae | 1983 |
Normal activities of hepatic pyruvate dehydrogenase and pyruvate carboxylase in Leigh's syndrome.
Topics: Brain; Brain Stem; Central Nervous System Diseases; Encephalomalacia; Humans; Infant; Intellectual Disability; Lactates; Lactic Acid; Liver; Male; Psychomotor Disorders; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Syndrome | 1983 |
Endotoxin dose. I. Hemodynamic, metabolic, and lethal consequences in Yucatan minipigs.
Topics: Animals; Anions; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Electrolytes; Endotoxins; Female; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Male; Oxygen; Pyruvates; Pyruvic Acid; Swine; Swine, Miniature | 1983 |
The influence of the thyroid state on energy turnover during tetanic stimulation in the fast-twitch (mixed type) muscle of rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Energy Metabolism; Hydrogen-Ion Concentration; In Vitro Techniques; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles; Phosphorylation; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Thyroid Hormones | 1983 |
Pyruvate and lactate levels in oviducts of cycling, pregnant, and pseudopregnant mice.
Topics: Analysis of Variance; Animals; Estrus; Fallopian Tubes; Female; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mice; Mice, Inbred Strains; Pregnancy; Pregnancy, Animal; Pseudopregnancy; Pyruvates; Pyruvic Acid | 1983 |
Influence of Sertoli cell products upon the in vitro survival of isolated spermatocytes and spermatids.
Topics: Animals; Cell Survival; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sertoli Cells; Spermatids; Spermatozoa | 1983 |
Age-related changes in rat adipose tissue in response to fasting: protein, lactate and pyruvate levels.
Topics: Adipose Tissue; Aging; Animals; Fasting; Lactates; Lactic Acid; Male; NAD; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Lactate and pyruvate content of the human cisternal cerebrospinal fluid. Normal values, age and sex dependency, correlations with glucose concentrations.
Topics: Adolescent; Adult; Aged; Aging; Blood Glucose; Cisterna Magna; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Reference Values; Sex Factors | 1983 |
Lactate dehydrogenase activity and lactate/pyruvate ratio in muscle of thermally acclimated goldfish.
Topics: Acclimatization; Animals; Cyprinidae; Glycogen; Goldfish; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Muscles; Physical Exertion; Pyruvates; Pyruvic Acid | 1983 |
Effects of pyridoxine alpha-ketoglutarate on blood glucose and lactate in type I and II diabetics.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus; Female; Hemoglobin A; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyridoxine; Pyruvates; Pyruvic Acid | 1983 |
Pharmacologic effects of metformin in relation to its disposition in alloxan diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Injections, Intravenous; Intestinal Absorption; Lactates; Lactic Acid; Male; Metformin; Models, Biological; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
The effect of diet on intermediary metabolite concentrations in Type 2 (non-insulin-dependent) diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Alanine; Diabetes Mellitus; Female; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Time Factors | 1983 |
Substrate utilization by rat stomach in vivo. Arteriovenous differences for glucose, lactate, ketone bodies, fatty acids and glycerol under control and acid-secreting conditions.
Topics: Animals; Arteries; Carbohydrate Metabolism; Fatty Acids; Gastric Acid; Gastric Mucosa; Glucose; Glycerol; Ketone Bodies; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Veins | 1983 |
Effect of postnatal hypoxia on the energy homeostasis of the newborn rat during the early neonatal period.
Topics: Adenine Nucleotides; Alanine; Animals; Animals, Newborn; Blood Glucose; Energy Metabolism; Glucagon; Homeostasis; Hypoxia; Lactates; Lactic Acid; Liver; Liver Glycogen; Oxygen; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1983 |
Energetics of growth of a defined mixed culture of Desulfovibrio vulgaris and Methanosarcina barkeri: maintenance energy coefficient of the sulfate-reducing organism in the absence and presence of its partner.
Topics: Culture Media; Desulfovibrio; Ecology; Energy Metabolism; Euryarchaeota; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Sulfates | 1983 |
The effect of diphenylhydantoin on metabolic and growth hormone changes during and after exercise.
Topics: Administration, Oral; Adult; Blood Glucose; Energy Metabolism; Fatty Acids, Nonesterified; Glycerol; Growth Hormone; Humans; Ketones; Lactates; Lactic Acid; Phenytoin; Physical Exertion; Pyruvates; Pyruvic Acid | 1983 |
Effect of ischemia on fatty acid metabolism in fetal lung.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fatty Acids; Female; Fetus; Ischemia; Kinetics; Lactates; Lactic Acid; Lung; NAD; Oxidation-Reduction; Pregnancy; Pulmonary Circulation; Pyruvates; Pyruvic Acid; Rabbits | 1983 |
Quantitative histochemical measurement of pyruvate and lactate in mouse oviduct during the estrous cycle.
Topics: Anaerobiosis; Animals; Estrus; Fallopian Tubes; Female; Histocytochemistry; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Malate Dehydrogenase; Mice; Pentobarbital; Pregnancy; Pyruvates; Pyruvic Acid | 1982 |
Studies on pyruvate carboxylase, pyruvate decarboxylase and lipoamide dehydrogenase in subacute necrotizing encephalomyelopathy.
Topics: Alanine; Brain Diseases; Carboxy-Lyases; Cells, Cultured; Dihydrolipoamide Dehydrogenase; Female; Fibroblasts; Humans; Infant; Lactates; Lactic Acid; Male; Necrosis; Pyruvate Carboxylase; Pyruvate Decarboxylase; Pyruvates; Pyruvic Acid | 1982 |
The lactate metabolism of the oral bacterium Veillonella from human saliva.
Topics: Acetates; Humans; Lactates; Lactic Acid; Oxaloacetates; Pyruvates; Pyruvic Acid; Saliva; Succinates; Succinic Acid; Veillonella | 1981 |
Biochemical properties of mammalian 2-oxo acid dehydrogenase multienzyme complexes and clinical relevancy with chronic lactic acidosis.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acidosis; Animals; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Kinetics; Lactates; Lactic Acid; Liver; Macromolecular Substances; Male; Microscopy, Electron; Mitochondria, Heart; Multienzyme Complexes; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Structure-Activity Relationship; Swine | 1982 |
Fructose-1,6-diphosphate (FDP), hemodynamics and heart metabolism: preliminary experimental studies.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Fructosediphosphates; Heart Rate; Hemodynamics; Hexosediphosphates; Lactates; Lactic Acid; Male; Myocardium; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1982 |
[Postmortem changes in the perilymphatic lactate and pyruvate concentrations of guinea pigs. (author's transl)].
Topics: Animals; Guinea Pigs; Labyrinthine Fluids; Lactates; Lactic Acid; Perilymph; Postmortem Changes; Pyruvates; Pyruvic Acid; Scala Tympani; Vestibule, Labyrinth | 1981 |
Isotachophoretic analyses of metabolites of cardiac and skeletal muscles in four species.
Topics: Adenine Nucleotides; Animals; Cricetinae; Dogs; Electrophoresis; Glucose-6-Phosphate; Glucosephosphates; Guinea Pigs; Inosine Monophosphate; Lactates; Lactic Acid; Muscles; Myocardium; Phosphates; Phosphocreatine; Pyruvates; Pyruvic Acid; Rana catesbeiana | 1982 |
Stimulus-secretion coupling of glucose-induced insulin release. Timing of early metabolic, ionic, and secretory events.
Topics: Animals; Calcium; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Lactates; Lactic Acid; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rubidium | 1981 |
Regionally selective metabolic effects of hypoglycemia in brain.
Topics: Adenosine Triphosphate; Animals; Brain; Electroencephalography; Fructosediphosphates; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glycogen; Hypoglycemia; Insulin; Lactates; Lactic Acid; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats | 1981 |
Effects of pregnancy and sex steroid administration on skeletal muscle metabolism in the rat.
Topics: Alanine; Animals; Estradiol; Female; Glucose; Glycerol; Insulin; Lactates; Lactic Acid; Muscles; Oxygen Consumption; Phenylalanine; Pregnancy; Pregnancy, Animal; Progesterone; Pyruvates; Pyruvic Acid; Rats | 1981 |
The acute metabolic effects of glucagon and its interactions with insulin in forearm tissue.
Topics: Blood Glucose; Fatty Acids, Nonesterified; Forearm; Glucagon; Glycerol; Humans; Insulin; Lactates; Lactic Acid; Lipolysis; Male; Perfusion; Potassium; Pyruvates; Pyruvic Acid; Regional Blood Flow | 1981 |
The effects of high ethanol doses on rates of ethanol oxidation in rats. A reassessment of factors controlling rates of ethanol oxidation in vivo.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Animals; Dose-Response Relationship, Drug; Ethanol; Lactates; Lactic Acid; Liver; Male; Metabolic Clearance Rate; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation | 1981 |
Hemodynamic responses to sepsis: hypodynamic versus hyperdynamic states.
Topics: Animals; Blood Cell Count; Escherichia coli Infections; Female; Hematology; Hemodynamics; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Swine | 1981 |
Effect of acetate on ketogenesis during hemodialysis.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetoacetates; Biological Transport; Blood Glucose; Female; Glucagon; Humans; Hydroxybutyrates; Insulin; Keto Acids; Ketone Bodies; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Renal Dialysis | 1982 |
Insulin "inhibition" of gluconeogenesis by stimulation of protein synthesis.
Topics: Alanine; Animals; Blood Glucose; Gluconeogenesis; Glycerol; Insulin; Lactates; Lactic Acid; Male; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Rabbits | 1981 |
Effect of insulin and leucine on protein turnover in rat soleus muscle after burn injury.
Topics: Adenosine Triphosphate; Animals; Atrophy; Burns; Insulin; Lactates; Lactic Acid; Leucine; Male; Muscles; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
[Carbohydrate infusion in internal diseases. A comparative study in metabolically healthy, liver diseased and diabetic patients. VI. Infusions of a glucose/xylitol mixture (1:1 ratio) over a 48-hour period].
Topics: Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucose; Glucose Solution, Hypertonic; Humans; Infusions, Parenteral; Insulin; Ketone Bodies; Lactates; Lactic Acid; Liver Cirrhosis; Pyruvates; Pyruvic Acid; Triglycerides; Uric Acid; Xylitol | 1982 |
Transient triiodothyronine deficiency. Absence of effect on basal or adrenaline-stimulated carbohydrate and lipid metabolism in man.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Carbohydrates; Epinephrine; Fatty Acids, Nonesterified; Glycerol; Humans; Hydroxybutyrates; Insulin; Ipodate; Lactates; Lactic Acid; Lipid Metabolism; Male; Pyruvates; Pyruvic Acid; Triiodothyronine | 1982 |
Impaired lactate utilization in livers of rats fed high protein-diets.
Topics: Alanine; Animals; Blood Glucose; Dietary Proteins; Gluconeogenesis; Intestinal Absorption; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats | 1982 |
Microcalorimetric studies of the growth of sulfate-reducing bacteria: comparison of the growth parameters of some Desulfovibrio species.
Topics: Calorimetry; Desulfovibrio; Hot Temperature; Kinetics; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Sulfates | 1982 |
Relationships between adenosine and coronary resistance in conscious exercising dogs.
Topics: Adenosine; Animals; Cardiac Output; Dogs; Female; Heart; Heart Rate; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid; Vascular Resistance | 1982 |
Intracellular compartmentation and control of alanine metabolism in rat liver parenchymal cells.
Topics: Alanine; Animals; Cytosol; In Vitro Techniques; Lactates; Lactic Acid; Liver; Mitochondria, Liver; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Subcellular Fractions; Thermodynamics | 1982 |
Effects of glucose, pyruvate, lactate, and amino acids on muscle protein synthesis.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Cytoplasm; Diaphragm; Energy Metabolism; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Oxidation-Reduction; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Rats; Time Factors | 1982 |
Fetal myocardial oxygen and carbohydrate consumption during acutely induced hypoxemia.
Topics: Animals; Blood Pressure; Coronary Circulation; Female; Fetus; Glucose; Heart; Heart Rate; Hypoxia; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Pregnancy; Pyruvates; Pyruvic Acid; Sheep | 1982 |
Changes in NAD(P)+-dependent malic enzyme and malate dehydrogenase activities during fibroblast proliferation.
Topics: Cell Division; Cell Fractionation; Cells, Cultured; Fibroblasts; Humans; Lactates; Lactic Acid; Malate Dehydrogenase; Malates; Manganese; Mitochondria; NAD; NADP; Oxaloacetates; Pyruvates; Pyruvic Acid | 1982 |
Effects of ascorbate on methemoglobin reduction in intact red cells.
Topics: Adult; Ascorbic Acid; Erythrocytes; Glucose; Hemoglobins; Humans; Lactates; Lactic Acid; Methemoglobin; Pyruvates; Pyruvic Acid | 1982 |
Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart.
Topics: Acetates; Alanine; Animals; Citrates; Citric Acid; Citric Acid Cycle; Female; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Malates; Myocardium; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
[Influence of differential hypothermia treatment on the cerebral metabolism (author's transl)].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Brain; Dihydroxyacetone Phosphate; Female; Fructosediphosphates; Glucose; Glucosephosphates; Hypothermia, Induced; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rabbits | 1982 |
Metabolism of round spermatids from rats: lactate as the preferred substrate.
Topics: Adenosine Triphosphate; Animals; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Male; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Spermatids; Spermatozoa | 1982 |
A p.m.r. isotope-exchange method for studying the kinetic properties of dehydrogenases in intact cells.
Topics: Erythrocytes; Humans; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Biological; Pyruvates; Pyruvic Acid | 1982 |
Studies of lactate dehydrogenase in the purified state and in intact erythrocytes.
Topics: Erythrocytes; Humans; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Biological; NAD; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid | 1982 |
A 1H n.m.r. study of isotope exchange catalysed by glycolytic enzymes in the human erythrocyte.
Topics: Carbohydrate Epimerases; Dihydroxyacetone Phosphate; Erythrocytes; Fructose-Bisphosphate Aldolase; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Biological; Pyruvates; Pyruvic Acid; Triose-Phosphate Isomerase | 1982 |
Prolonged hypolactatemia and increased total pyruvate dehydrogenase activity by dichloroacetate.
Topics: Acetates; Animals; Blood Glucose; Dichloroacetic Acid; Glyoxylates; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxalates; Oxalic Acid; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Changes in some metabolites contents of the carbohydrate metabolism in mouse submandibular salivary gland after stimulation by isoproterenol.
Topics: Animals; Carbohydrate Metabolism; Citrates; Citric Acid; Isoproterenol; Lactates; Lactic Acid; Male; Mice; NAD; Pyruvates; Pyruvic Acid; Submandibular Gland | 1982 |
Inhibition of paranitroanisole and antipyrine monooxygenation in isolated rat hepatocytes by compounds interacting with mitochondrially related carbohydrate metabolism.
Topics: Ammonium Chloride; Animals; Anisoles; Antipyrine; Carbohydrate Metabolism; Fasting; Lactates; Lactic Acid; Male; Mitochondria, Liver; Mixed Function Oxygenases; Oxidoreductases; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
A simple, rapid method for the determination of glucose, lactate, pyruvate, alanine, 3-hydroxybutyrate and acetoacetate on a single 20-mul blood sample.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Blood Glucose; Fluorometry; Humans; Hydroxybutyrates; Keto Acids; Lactates; Lactic Acid; Methods; Microchemistry; NAD; Physical Exertion; Pyruvates; Pyruvic Acid; Spectrophotometry; Starvation | 1982 |
Quantification of pathways of glucose utilization and balance of energy metabolism of rabbit reticulocytes.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Energy Metabolism; Erythrocytes; In Vitro Techniques; Lactates; Lactic Acid; Mathematics; Oxidative Phosphorylation; Pyruvates; Pyruvic Acid; Rabbits; Reticulocytes | 1982 |
Impaired acetaldehyde oxidation in alcoholics.
Topics: Acetaldehyde; Adult; Alcoholism; Aldehyde Oxidoreductases; Ethanol; Humans; Lactates; Lactic Acid; Liver; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1982 |
Metabolic effects of pyridoxine alpha-ketoglutarate in ophthalmoplegia plus.
Topics: Adolescent; Adult; Female; Humans; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Ophthalmoplegia; Pyridoxine; Pyruvates; Pyruvic Acid | 1982 |
Energy metabolism and ATP turnover time during the cell cycle of Ehrlich ascites tumour cells.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Energy Metabolism; Glycolysis; Interphase; Kinetics; Lactates; Lactic Acid; Mice; Mitosis; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1982 |
Relationship of the reduction-oxidation state to protein degradation in skeletal and atrial muscle.
Topics: Animals; Diaphragm; Heart Atria; Lactates; Lactic Acid; Leucine; Malates; Male; Muscle Proteins; Muscles; NAD; Oxidation-Reduction; Protease Inhibitors; Pyruvates; Pyruvic Acid; Rats | 1982 |
Cadmium toxicity in primary cultures of rat hepatocytes.
Topics: Animals; Cadmium; Chemical and Drug Induced Liver Injury; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1982 |
Intracellular oxygen supply during hypoxia.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Anaerobiosis; Animals; Cytochromes; Glutathione; Hypoxia; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats | 1982 |
Pathways for carboxylic acid transport by rabbit renal brush border membrane vesicles.
Topics: Animals; Biological Transport; Carboxylic Acids; Cell Membrane; Kidney Cortex; Kinetics; Lactates; Lactic Acid; Microvilli; Pyruvates; Pyruvic Acid; Rabbits; Structure-Activity Relationship; Succinates; Succinic Acid | 1982 |
Accumulation and disposal of tricarboxylic acid cycle intermediates during propionate oxidation in the isolated perfused rat heart.
Topics: Alanine; Animals; Biological Transport; Carbon Radioisotopes; Citric Acid Cycle; Female; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Oxidation-Reduction; Perfusion; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
Modulation of phosphate accumulation in isolated chick kidney cells by gluconeogenic substrates.
Topics: Animals; Chickens; Gluconeogenesis; Glucose; Kidney Tubules, Proximal; Kinetics; Lactates; Lactic Acid; Male; Phosphates; Pyruvates; Pyruvic Acid | 1982 |
Determination of D-lactate in plasma.
Topics: Catalysis; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Spectrophotometry | 1982 |
Fetal myocardial oxygen and carbohydrate metabolism in sustained hypoxemia in utero.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Coronary Vessels; Female; Fetus; Heart; Hypoxia; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Pregnancy; Pyruvates; Pyruvic Acid; Sheep | 1982 |
Effect of temperature on the red and white muscle lactate dehydrogenase of thermally acclimated goldfish.
Topics: Adaptation, Physiological; Animals; Cold Temperature; Cyprinidae; Drug Stability; Goldfish; Hot Temperature; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Muscles; Pyruvates; Pyruvic Acid | 1982 |
Concentrations of lactate and pyruvate and temperature effects on lactate dehydrogenase activity in the tissues of the big brown bat (Eptesicus fuscus) during arousal from hibernation.
Topics: Animals; Arousal; Body Temperature; Chiroptera; Hibernation; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Mathematics; Muscles; Myocardium; Pyruvates; Pyruvic Acid | 1982 |
Metabolism of glucose and glycogen in Limulus polyphemus in vivo.
Topics: Animals; Blood Glucose; Glucose; Glycogen; Horseshoe Crabs; Lactates; Lactic Acid; Liver; Muscles; Pancreas; Pyruvates; Pyruvic Acid | 1982 |
[Effect of recirculation on experimental cerebral ischemia. 3. Therapy].
Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Carotid Arteries; Cerebrovascular Circulation; Dexamethasone; Glycerol; Hypertension; Lactates; Lactic Acid; Ligation; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Ubiquinone | 1982 |
The study of organic acids metabolism in a patient with ornithine transcarbamylase (OTC) deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Child; Citrates; Citric Acid; Female; Humans; Ketoglutaric Acids; Lactates; Lactic Acid; Liver; Ornithine Carbamoyltransferase Deficiency Disease; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid | 1982 |
alpha-Ketoglutarate induced transamination during ischemic exercise.
Topics: Adult; Amination; Ammonia; Citric Acid Cycle; Energy Metabolism; Humans; Ischemia; Ketoglutaric Acids; Lactates; Lactic Acid; Ornithine; Physical Exertion; Pyruvates; Pyruvic Acid | 1982 |
A 1H n.m.r. study of the kinetic properties expressed by glyceraldehyde phosphate dehydrogenase in the intact human erythrocyte.
Topics: Erythrocyte Membrane; Erythrocytes; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Biological; NAD; Pyruvates; Pyruvic Acid | 1982 |
[Changes in the oxidative metabolism of the brain in the elderly].
Topics: Adult; Aged; Brain; Glucose; Humans; Lactates; Lactic Acid; Middle Aged; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1981 |
Succinylcholine in congenital pyruvate kinase deficiency.
Topics: Anesthesia; Child, Preschool; Cholesteatoma; Female; Humans; Lactates; Lactic Acid; Potassium; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Succinylcholine | 1982 |
Inhibition, by 2-oxo acids that accumulate in maple-syrup-urine disease, of lactate, pyruvate, and 3-hydroxybutyrate transport across the blood-brain barrier.
Topics: 3-Hydroxybutyric Acid; Animals; Blood-Brain Barrier; Brain; Humans; Hydroxybutyrates; Keto Acids; Kinetics; Lactates; Lactic Acid; Maple Syrup Urine Disease; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Pathophysiology of metabolic acidosis: effect of low pH on the hepatic uptake of lactate, pyruvate and alanine.
Topics: Acidosis; Alanine; Animals; Blood Glucose; Female; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
Dichloroacetate: effects on exercise endurance in untrained rats.
Topics: 3-Hydroxybutyric Acid; Acetates; Adenosine Triphosphate; Animals; Dichloroacetic Acid; Glycogen; Hydroxybutyrates; Lactates; Lactic Acid; Male; Muscles; Phosphocreatine; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Time Factors | 1981 |
Effect of adenosine on gluconeogenesis in the perfused liver of chicken and guinea-pig.
Topics: Adenosine; Animals; Aspartic Acid; Chickens; Female; Gluconeogenesis; Guinea Pigs; Humans; Lactates; Lactic Acid; Liver; Malates; Perfusion; Pyruvates; Pyruvic Acid | 1981 |
Disturbances of lactate metabolism in patients with liver damage due to paracetamol overdose.
Topics: Acetaminophen; Adult; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Viral, Human; Humans; Ketoglutaric Acids; Kinetics; Lactates; Lactic Acid; Liver; Liver Diseases; Male; Middle Aged; Muscles; Pyruvates; Pyruvic Acid | 1981 |
Effect of oral administration of lipids with 67% medium chain triglycerides on glucose homeostasis in preterm neonates.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Blood Glucose; Dietary Fats; Fatty Acids, Nonesterified; Glucose Tolerance Test; Glycerol; Homeostasis; Humans; Hydroxybutyrates; Infant, Newborn; Infant, Premature; Keto Acids; Kinetics; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Structure-Activity Relationship; Triglycerides | 1981 |
Myocardial consumption of oxygen and carbohydrates in newborn sheep.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Glucose; Coronary Vessels; Fetus; Lactates; Lactic Acid; Myocardium; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Sheep | 1981 |
Metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Topics: Adenine Nucleotides; Animals; Cerebral Cortex; Dogs; Female; Hypoxia; Lactates; Lactic Acid; Oxygen Consumption; Papaverine; Phenobarbital; Phosphocreatine; Pyruvates; Pyruvic Acid; Synaptosomes; Vinca Alkaloids | 1981 |
Correlation of changes in blood chemistry with pathological changes in the animal's body: II Electrolytes, kidney function tests, serum enzymes, and liver function tests.
Topics: Animals; Blood Urea Nitrogen; Calcium; Cats; Cattle; Cattle Diseases; Chlorides; Dogs; Electrolytes; Enzymes; Female; Goats; Horses; Hydrogen-Ion Concentration; Kidney Function Tests; Lactates; Lactic Acid; Liver Function Tests; Magnesium; Phosphorus; Potassium; Pyruvates; Pyruvic Acid; Sheep; Sodium; Swine | 1981 |
Effects of glucagon on hepatic glycogen and smooth endoplasmic reticulum.
Topics: Animals; Blood Glucose; Endoplasmic Reticulum; Glucagon; Glucose; Histocytochemistry; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Pyruvates; Pyruvic Acid; Rats | 1981 |
[Histo- and biochemical characteristics of rat skeletal muscle after prolonged static loading].
Topics: Animals; Glycogen; Histocytochemistry; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Muscles; Organ Specificity; Physical Exertion; Posture; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinate Dehydrogenase | 1981 |
Metabolic consequences of pyruvate kinase inhibition by oxalate in intact rat hepatocytes.
Topics: Animals; Fasting; Female; Gluconeogenesis; Glycolysis; Lactates; Lactic Acid; Liver; Oxalates; Oxalic Acid; Phosphoenolpyruvate; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1981 |
[Hexokinase and lactate dehydrogenase activity, lactic and pyruvic acid content of erythrocytes and acid-base equilibrium in stomach cancer patients after radical operations].
Topics: Acid-Base Equilibrium; Adult; Aged; Enzyme Activation; Erythrocytes; Gastrectomy; Hexokinase; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Middle Aged; Postoperative Period; Pyruvates; Pyruvic Acid; Stomach Neoplasms | 1981 |
Effect of increasing the intracellular ratio of NADH to NAD+ on human erythrocyte metabolism: new estimation of the turnover through the phosphoglycerate shunt.
Topics: 2,3-Diphosphoglycerate; Adenine Nucleotides; Diphosphoglyceric Acids; Erythrocytes; Glyceric Acids; Humans; In Vitro Techniques; Lactates; Lactic Acid; NAD; Organophosphorus Compounds; Oxidation-Reduction; Phosphates; Pyruvates; Pyruvic Acid | 1981 |
Carbohydrate metabolism in isolated, working newborn pig heart.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Blood Pressure; Buffers; Carbohydrate Metabolism; Glucose; Glycogen; Heart; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Perfusion; Phosphocreatine; Pyruvates; Pyruvic Acid; Swine | 1981 |
Effect of acute ammonia intoxication on energy stores in the cerebral reticular activating system.
Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Brain Stem; Energy Metabolism; Female; Glycogen; Kinetics; Lactates; Lactic Acid; Mice; Phosphocreatine; Pyruvates; Pyruvic Acid | 1981 |
Effects of endosulfan on fish carbohydrate metabolism.
Topics: Animals; Behavior, Animal; Blood Glucose; Carbohydrate Metabolism; Endosulfan; Fishes; Glycogen; Lactates; Lactic Acid; Liver; Muscles; Pyruvates; Pyruvic Acid; Time Factors | 1981 |
In vitro cultivation of bloodstream forms of Trypanosoma brucei, T. rhodesiense, and T. gambiense.
Topics: Animals; Blood; Culture Media; Fibroblasts; Glucose; Lactates; Lactic Acid; Methods; Pyruvates; Pyruvic Acid; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma brucei gambiense | 1981 |
Vascular and metabolic effects of methylprednisolone and phenoxybenzamine during controlled hypotension in the dog.
Topics: Animals; Dogs; Hydrogen-Ion Concentration; Hypotension, Controlled; Lactates; Lactic Acid; Male; Methylprednisolone; Muscles; Oxygen Consumption; Phenoxybenzamine; Phosphocreatine; Pyruvates; Pyruvic Acid; Receptors, Adrenergic; Shock, Hemorrhagic; Vascular Resistance; Vasodilation | 1981 |
Influence of abdominal surgical trauma on substrate utilization by the human brain.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Blood Glucose; Brain; Cholecystectomy; Female; Glucose; Glycerol; Humans; Hydroxybutyrates; Lactates; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Pyruvates; Pyruvic Acid; Surgical Procedures, Operative | 1981 |
Cerebral blood flow and metabolic rate of oxygen, glucose, lactate, pyruvate, ketone bodies and amino acids.
Topics: Aged; Alzheimer Disease; Amino Acids; Brain; Cerebrospinal Fluid Shunts; Cerebrovascular Circulation; Dementia; Humans; Hydrocephalus; Hydrocephalus, Normal Pressure; Ketone Bodies; Lactates; Lactic Acid; Middle Aged; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1981 |
The rôle of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes.
Topics: Animals; Biological Transport; Coumaric Acids; Glucagon; Gluconeogenesis; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Phenylephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1981 |
Canine cerebral metabolism and blood flow during hypoxemia and normoxic recovery from hypoxemia.
Topics: Acidosis; Adenine Nucleotides; Animals; Brain; Dogs; Electroencephalography; Glucose; Hypoxia; Lactates; Lactic Acid; Oxygen; Phosphocreatine; Pyruvates; Pyruvic Acid | 1981 |
Effects of lactate, pyruvate, butyrate and ammonia on gluconeogenesis from propionate by isolated rabbit liver cells.
Topics: Ammonia; Animals; Butyrates; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Liver; Propionates; Pyruvates; Pyruvic Acid; Rabbits | 1980 |
Metabolism of [3-13C]pyruvate and [3-13C]propionate in normal and ischaemic rat heart in vivo: 1H- and 13C-NMR studies.
Topics: Acetyl Coenzyme A; Alanine; Animals; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1995 |
Hepatotoxic effects of hexachlorocyclohexane on carbohydrate metabolism of a freshwater fish Channa punctatus (Bloch).
Topics: Animals; Carbohydrate Metabolism; Fishes; Glucose; Glucosephosphate Dehydrogenase; Glycogen; Hexachlorocyclohexane; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lethal Dose 50; Liver; Malate Dehydrogenase; Pest Control; Phosphorylase a; Phosphorylases; Pyruvates; Pyruvic Acid; Succinate Dehydrogenase; Water Pollutants | 1994 |
Bivascular liver perfusion in the anterograde and retrograde modes: zonation of the response to inhibitors of oxidative phosphorylation.
Topics: 2,4-Dinitrophenol; Animals; Atractyloside; Cyanides; Dinitrophenols; Glucose; Glycogen; Glycolysis; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Oxygen; Perfusion; Phosphorylation; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Sucrose; Water | 1995 |
Lactate transport in cultured glial cells.
Topics: Animals; Astrocytes; Cells, Cultured; Female; Glioma; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Neuroglia; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Tumor Cells, Cultured | 1995 |
Acidic, pyruvate-based peritoneal dialysis solutions: relationship between low titratable acidity and biocompatibility.
Topics: Biocompatible Materials; Dialysis Solutions; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Peritoneal Dialysis, Continuous Ambulatory; Pyruvates; Pyruvic Acid; Titrimetry | 1995 |
Pyruvate neutralizes peritoneal dialysate cytotoxicity: maintained integrity and proliferation of cultured human mesothelial cells.
Topics: Cell Division; Cells, Cultured; Dialysis Solutions; Epithelium; Glucose; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Peritoneal Dialysis; Peritoneum; Pyruvates; Pyruvic Acid; Receptors, Interleukin-1; Thymidine | 1995 |
The influence of lactate, pyruvate and glucose as exogenous substrates on free radical defense mechanisms in isolated rat hearts during ischaemia and reperfusion.
Topics: Animals; Antioxidants; Catalase; Free Radicals; Glucose; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hemodynamics; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Lew; Superoxide Dismutase | 1995 |
Interaction of decreased arterial PO2 and exercise on carbohydrate metabolism in the dog.
Topics: Animals; Arteries; Blood Glucose; Carbohydrate Metabolism; Dogs; Female; Hemodynamics; Lactates; Lactic Acid; Male; Oxygen; Partial Pressure; Physical Exertion; Pyruvates; Pyruvic Acid | 1995 |
Skeletal muscle pyruvate dehydrogenase activity during maximal exercise in humans.
Topics: Adenine Nucleotides; Adult; Carbon Dioxide; Coenzyme A; Cytosol; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Mitochondria; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Physical Endurance; Physical Exertion; Pulmonary Gas Exchange; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Respiration | 1995 |
Hepatocyte injury resulting from the inhibition of mitochondrial respiration at low oxygen concentrations involves reductive stress and oxygen activation.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Antioxidants; Cell Death; Cell Hypoxia; Cyanides; Ethanol; Hydrogen Peroxide; Iron; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1995 |
Glial formation of pyruvate and lactate from TCA cycle intermediates: implications for the inactivation of transmitter amino acids?
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Citric Acid Cycle; Female; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Neuroglia; Neurotransmitter Agents; Pyruvates; Pyruvic Acid | 1995 |
Whole animal, lung and muscle hemodynamics and function are maintained during and after Oxygent HT infusion.
Topics: Animals; Biological Transport, Active; Dogs; Emulsions; Fluorocarbons; Hemodynamics; Hydrocarbons, Brominated; Infusions, Intravenous; Lactates; Lactic Acid; Lung; Muscle, Skeletal; Oxygen; Pyruvates; Pyruvic Acid | 1994 |
Lactate dehydrogenase M-subunit deficiencies: clinical features, metabolic background, and genetic heterogeneities.
Topics: Adolescent; Adult; Base Sequence; DNA; Exercise; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Molecular Sequence Data; Mutation; Myoglobinuria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Skin Diseases | 1995 |
Mitochondrial enzyme deficiency in cerebrotendinous xanthomatosis.
Topics: Adult; Biopsy; Brain Diseases; Electron Transport; Female; Humans; Lactates; Lactic Acid; Mitochondria, Muscle; Muscles; Pyruvates; Pyruvic Acid; Tendons; Xanthomatosis | 1995 |
Utilization of short-chain monocarboxylic acids by the yeast Torulaspora delbrueckii: specificity of the transport systems and their regulation.
Topics: Acetates; Acetic Acid; Biological Transport; Carboxylic Acids; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae | 1995 |
Cardiac responses to induced lactate oxidation: NMR analysis of metabolic equilibria.
Topics: Animals; Carbon; Carbon Isotopes; Energy Metabolism; Heart; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardial Contraction; Myocardium; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rabbits | 1995 |
Octanoate affects 2,4-dinitrophenol uncoupling in intact isolated rat hepatocytes.
Topics: 2,4-Dinitrophenol; Adenine Nucleotides; Animals; Aspartic Acid; Caprylates; Cell Separation; Dihydroxyacetone; Dinitrophenols; Electron Transport; Fatty Acids; Glucose; Lactates; Lactic Acid; Liver; Malates; Male; NAD; Oxidation-Reduction; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1995 |
Protection by pyruvate against inhibition of Na+, K(+)-ATPase by a free radical generating system containing t-butylhydroperoxide.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Free Radicals; Glucose; Guinea Pigs; Horseradish Peroxidase; Kidney Cortex; Lactates; Lactic Acid; Male; Mannitol; Microsomes; Myocardium; Peroxides; Pyruvates; Pyruvic Acid; Rats; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; tert-Butylhydroperoxide | 1995 |
Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion.
Topics: Animals; Cytosol; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lactates; Lactic Acid; Malates; Male; Mitochondria; NADP; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Succinates | 1995 |
Lactate and pyruvate stimulate the conversion of glucose to glycogen in hepatocytes by a mechanism that does not involve gluconeogenic flux.
Topics: Amiloride; Animals; Glucose; Glycogen; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Male; Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1995 |
Effect of endosulfan 35 EC on some biochemical changes in the tissues and haemolymph of a freshwater field crab, Barytelphusa guerini.
Topics: Animals; Brachyura; Endosulfan; Fresh Water; Ganglia, Invertebrate; Gills; Heart; Hemolymph; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lethal Dose 50; Liver; Male; Muscle, Skeletal; Myocardium; Pancreas; Pyruvates; Pyruvic Acid; Succinate Dehydrogenase; Water Pollutants, Chemical | 1995 |
Dynamics of myocardial metabolism in the preconditioned porcine heart studied using continuous microdialysis.
Topics: Adenine Nucleotides; Animals; Cardiac Output; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrocardiography; Female; Lactates; Lactic Acid; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Pulmonary Wedge Pressure; Pyruvates; Pyruvic Acid; Swine | 1995 |
Concentrations of catecholamines in transplanted hearts after extracorporeal perfusion and cold storage.
Topics: Animals; Cold Temperature; Disease Models, Animal; Heart Transplantation; Lactates; Lactic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Organ Preservation; Perfusion; Pyruvates; Pyruvic Acid; Random Allocation; Swine; Swine, Miniature | 1995 |
[The walking-through phenomenon in arterial occlusive disease].
Topics: Adult; Aged; Arterial Occlusive Diseases; Exercise Test; Exercise Therapy; Glycolysis; Humans; Intermittent Claudication; Ischemia; Lactates; Lactic Acid; Leg; Male; Middle Aged; Pyruvates; Pyruvic Acid; Walking | 1995 |
Supersensitivity to beta-adrenoceptor stimulation evoked in cultured neonatal rat heart myocytes by L(+)-lactate and pyruvate.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Cinnamates; Cyclic AMP; Heart; Heart Rate; Isoproterenol; Lactates; Lactic Acid; Monocarboxylic Acid Transporters; Protein Kinases; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stereoisomerism | 1993 |
The isoenzyme forms of lactate dehydrogenase from the testes of Uromastix hardwickii.
Topics: Animals; Chromatography, Agarose; Colchicine; Electrophoresis, Polyacrylamide Gel; Ethanolamines; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Lizards; Male; NAD; Pyruvates; Pyruvic Acid; Testis | 1994 |
Recovery of power output and muscle metabolites following 30 s of maximal sprint cycling in man.
Topics: Adenosine Triphosphate; Adult; Ammonia; Ergometry; Glycogen; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Muscle Fatigue; Muscle, Smooth; Phosphocreatine; Physical Exertion; Pyruvates; Pyruvic Acid | 1995 |
Expression and subcellular distribution of phosphoenolpyruvate carboxykinase in primary cultures of rabbit kidney proximal tubule cells: comparative study with renal and hepatic PEPCK in vivo.
Topics: Animals; Bucladesine; Cells, Cultured; Culture Media; Cytosol; Glucose; Insulin; Kidney Tubules, Proximal; Kinetics; Lactates; Lactic Acid; Liver; Mitochondria; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Pyruvic Acid; Rabbits; Rats; Rats, Wistar; RNA, Messenger; Subcellular Fractions | 1995 |
Presentation and clinical investigation of mitochondrial respiratory chain disease. A study of 51 patients.
Topics: Adolescent; Adult; Alanine; Brain; Child; Creatine Kinase; DNA, Mitochondrial; Electroencephalography; Electromyography; Electron Transport; Electron Transport Complex IV; Humans; Lactates; Lactic Acid; Mitochondrial Encephalomyopathies; Pyruvates; Pyruvic Acid; Sarcolemma | 1995 |
Proportional activation coefficients during stimulation of oxidative phosphorylation by lactate and pyruvate or by vasopressin.
Topics: Animals; Binding Sites; Fatty Acids; Lactates; Lactic Acid; Male; Membrane Potentials; Mitochondria, Liver; Mitochondria, Muscle; Oxidative Phosphorylation; Pyruvates; Pyruvic Acid; Quinolinic Acid; Rats; Rats, Wistar; Vasopressins | 1995 |
Effect of galactosamine-induced hepatitis on the aerobic and anaerobic metabolism of the rat exposed to high-altitude hypoxia.
Topics: Aerobiosis; Altitude; Anaerobiosis; Animals; Citrate (si)-Synthase; Energy Metabolism; Fatty Acids; Fructose-Bisphosphatase; Fumarate Hydratase; Galactosamine; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Hepatitis, Animal; Hypoxia; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1995 |
Purification and properties of lactate dehydrogenase from liver of Uromastix hardwickii.
Topics: Animals; Cations, Divalent; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Glutamic Acid; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Lizards; Molecular Weight; NAD; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid | 1995 |
Hormone effects on hepatic substrate preference in sepsis.
Topics: Alanine; Animals; Energy Metabolism; Gluconeogenesis; Hormones; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Oxygen Consumption; Peritonitis; Phenylephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sepsis; Substrate Specificity; Urea | 1994 |
Lactate and pyruvate isotopic enrichments in plasma and tissues of postabsorptive and starved rats.
Topics: Animals; Blood; Eating; Lactates; Lactic Acid; Male; Microdialysis; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Starvation | 1995 |
Mechanism of gluconeogenesis inhibition in rat hepatocytes isolated after in vivo hypoxia.
Topics: Adenine Nucleotides; Animals; Cell Separation; Dihydroxyacetone; Gluconeogenesis; Hypoxia; Lactates; Lactic Acid; Liver; Male; Oxygen Consumption; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Time Factors | 1995 |
Assay of dehydrogenases with an O2-consuming biosensor.
Topics: Animals; Bacterial Proteins; Biosensing Techniques; Cell Survival; Chloromercuribenzoates; Electrodes; Electron Transport; Enzymes, Immobilized; Equipment Design; Escherichia coli; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mixed Function Oxygenases; NAD; Oxidation-Reduction; Oxidoreductases; Oxygen; p-Chloromercuribenzoic Acid; Pyruvates; Pyruvic Acid; Sensitivity and Specificity | 1994 |
Transient rise of glucose uptake in the fetal rat brain after brief episodes of intrauterine ischemia.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Deoxyglucose; Energy Metabolism; Female; Glucose; Glycolysis; Kinetics; Lactates; Lactic Acid; Phosphocreatine; Placental Circulation; Pregnancy; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Reperfusion | 1994 |
Human tubal fluid: formation and composition during vascular perfusion of the fallopian tube.
Topics: Adult; Body Fluids; Catheterization; Fallopian Tubes; Female; Follicular Phase; Glucose; Humans; Hysterectomy; Lactates; Lactic Acid; Microscopy, Electron, Scanning; Perfusion; Pyruvates; Pyruvic Acid | 1995 |
Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig.
Topics: Adenosine; Animals; Energy Metabolism; Female; Guanosine; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyruvates; Pyruvic Acid; Swine | 1995 |
Pyruvate anions neutralize peritoneal dialysate cytotoxicity.
Topics: Cell Division; Cell Survival; Cells, Cultured; Cytokines; Dialysis Solutions; DNA Replication; Epithelial Cells; Epithelium; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Macrophages, Peritoneal; Peritoneal Dialysis, Continuous Ambulatory; Pyruvates; Pyruvic Acid; Superoxides | 1995 |
[Metabolic effects of intermittent exercise by patients with stage II arterial occlusive disease].
Topics: Arterial Occlusive Diseases; Energy Metabolism; Exercise Test; Glycolysis; Humans; Ischemia; Lactates; Lactic Acid; Leg; Male; Middle Aged; Oxygen; Pyruvates; Pyruvic Acid | 1995 |
Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.
Topics: Brain; Carbon Isotopes; Citric Acid Cycle; Glucose; Glutamic Acid; Glutamine; Glycolysis; Humans; Ketoglutaric Acids; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mathematics; Models, Biological; Oxygen Consumption; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid | 1995 |
Evaluation of cultured hamster hepatocytes as an experimental model for the study of very low density lipoprotein secretion.
Topics: Animals; Anticholesteremic Agents; Cells, Cultured; Cholesterol; Cholesterol Esters; Cholesterol, Dietary; Cricetinae; Dexamethasone; Lactates; Lactic Acid; Lipoproteins, VLDL; Liver; Lovastatin; Male; Mesocricetus; Models, Biological; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Triglycerides | 1995 |
Lactate and pyruvate concentrations in capillary blood from newborns.
Topics: Adolescent; Adult; Capillaries; Female; Heel; Humans; Infant, Newborn; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Reference Values; Time Factors | 1994 |
Gastric mucosal high-energy phosphate metabolism. Influence of ethanol and PGE2.
Topics: Adenine Nucleotides; Animals; Dinoprostone; Energy Metabolism; Ethanol; Female; Gastric Mucosa; Glucose; Glucose-6-Phosphate; Glucosephosphates; Lactates; Lactic Acid; Oxidative Phosphorylation; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1995 |
Mitochondrial pyruvate metabolism in liver and kidney during acidosis.
Topics: Acidosis; Alanine; Ammonium Chloride; Animals; Fasting; Gluconeogenesis; Kidney Cortex; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mitochondria; Mitochondria, Liver; Physical Conditioning, Animal; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Catecholamine-induced cAMP response in streptozotocin-induced diabetic rat liver.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Emaciation; Epinephrine; Glucagon; Glucose; Insulin; Isoproterenol; Lactates; Lactic Acid; Liver; Male; Oxymetazoline; Phenylephrine; Propranolol; Pyruvates; Pyruvic Acid; Rats; Receptors, Adrenergic, beta; Streptozocin | 1994 |
Insulin-independent and extremely rapid switch in the partitioning of hepatic fatty acids from oxidation to esterification in starved-refed diabetic rats. Possible roles for changes in cell pH and volume.
Topics: Animals; Carnitine O-Palmitoyltransferase; Cholesterol Esters; Diabetes Mellitus, Experimental; Esterification; Fatty Acids; Fatty Acids, Nonesterified; Female; Food; Glycerophosphates; Insulin; Lactates; Lactic Acid; Liver; Malonyl Coenzyme A; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Starvation | 1995 |
Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Neuropathies; Eye; Fructose; Glycated Hemoglobin; L-Iditol 2-Dehydrogenase; Lactates; Lactic Acid; Male; Pyrimidines; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Sorbitol | 1995 |
Subcellular localization of PEPCK and metabolism of gluconeogenic substrains of renal cell lines.
Topics: Aminooxyacetic Acid; Blotting, Northern; Cell Line; Cytosol; Fructose-Bisphosphatase; Gluconeogenesis; Kidney; Lactates; Lactic Acid; Mitochondria; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Pyruvic Acid; RNA, Messenger; Subcellular Fractions; Time Factors; Tissue Distribution | 1995 |
Meta-iodobenzylguanidine inhibits complex I and III of the respiratory chain in the human cell line Molt-4.
Topics: 3-Iodobenzylguanidine; Adenosine Triphosphate; Cell Division; Culture Media; Electron Transport Complex III; Humans; Iodobenzenes; Lactates; Lactic Acid; NAD(P)H Dehydrogenase (Quinone); Pyruvates; Pyruvic Acid; Tumor Cells, Cultured | 1995 |
Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency.
Topics: Acidosis, Lactic; Agenesis of Corpus Callosum; Brain; Brain Damage, Chronic; Brain Diseases, Metabolic; Corpus Callosum; Diagnosis, Differential; Female; Follow-Up Studies; Genetic Carrier Screening; Humans; Infant; Infant, Newborn; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurologic Examination; Phosphates; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid; Sex Chromosome Aberrations; X Chromosome | 1994 |
The role of exogenous energy substrates in blastocoele fluid accumulation in the rat.
Topics: Animals; Blastocyst; Energy Metabolism; Female; Glucose; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Substrate Specificity | 1994 |
Preservation of sarcoplasmic reticulum Ca2(+)-sequestering function in homogenates of different type composition following sprint activity.
Topics: Adenosine Triphosphatases; Animals; Calcium; Calcium-Transporting ATPases; Creatine; Glycogen; In Vitro Techniques; Lactates; Lactic Acid; Male; Muscle, Skeletal; Nucleotides; Phosphates; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Sarcoplasmic Reticulum | 1994 |
Increased CSF pyruvate levels as a marker of impaired energy metabolism in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Case-Control Studies; Energy Metabolism; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1995 |
Properties of a lactate-induced relaxation in human placental arteries and veins.
Topics: Analysis of Variance; Arginine; Arteries; Colforsin; Cyanides; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Guanylate Cyclase; Humans; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Lactates; Lactic Acid; Methylene Blue; Nitroarginine; Nitroglycerin; Oxygen; Placenta; Pregnancy; Prostaglandin-Endoperoxide Synthases; Pyruvates; Pyruvic Acid; Vasoconstriction; Veins | 1993 |
Isotopomer studies of gluconeogenesis and the Krebs cycle with 13C-labeled lactate.
Topics: Acetyl Coenzyme A; Alanine; Animals; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Isotope Labeling; Lactates; Lactic Acid; Liver; Male; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Lipoamide influences substrate selection in post-ischaemic perfused rat hearts.
Topics: Acetates; Acetylation; Animals; Aspartic Acid; Binding, Competitive; Carbon Isotopes; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thioctic Acid | 1994 |
Orientation-conserved transfer of symmetric Krebs cycle intermediates in mammalian tissue.
Topics: Acetates; Animals; Biological Transport; Carbon Isotopes; Citrates; Citric Acid; Citric Acid Cycle; Fumarates; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Myocardium; Propionates; Pyruvates; Pyruvic Acid; Rats; Succinates; Succinic Acid | 1994 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Guanosine Diphosphate; Guanosine Triphosphate; Lactates; Lactic Acid; Male; Neurotransmitter Agents; Nitro Compounds; Oxygen Consumption; Phosphocreatine; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 1994 |
Biochemical diversity within the "Mycoplasma mycoides" cluster.
Topics: Animals; Carbohydrate Metabolism; Cattle; Cattle Diseases; Glycerol; Goat Diseases; Goats; Lactates; Lactic Acid; Mycoplasma; Oxygen; Pneumonia, Mycoplasma; Pyruvates; Pyruvic Acid; Sheep; Sheep Diseases; Species Specificity | 1994 |
Zonation of the action of glucagon on gluconeogenesis studied in the bivascularly perfused rat liver.
Topics: Albinism; Animals; Glucagon; Gluconeogenesis; Glucose; Hepatic Artery; Lactates; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Determination of the anaerobic threshold by gas exchange: biochemical considerations, methodology and physiological effects.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Anaerobic Threshold; Bicarbonates; Carbon Dioxide; Energy Metabolism; Exercise Test; Glycolysis; Heart Diseases; Humans; Lactates; Lactic Acid; Oxygen; Physical Fitness; Pulmonary Gas Exchange; Pyruvates; Pyruvic Acid; Spirometry | 1994 |
Loss of fatty acid control of gluconeogenesis and PDH complex flux in adrenalectomized rats.
Topics: Adrenalectomy; Animals; Fatty Acids; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Reference Values | 1994 |
Calculation of inspired oxygen fraction during anaesthesia based on awake oxygen saturation.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Blood Pressure; Female; Heart Rate; Humans; Intraoperative Period; Lactates; Lactic Acid; Male; Middle Aged; Nitrous Oxide; Oximetry; Oxygen; Partial Pressure; Pyruvates; Pyruvic Acid | 1994 |
Metabolic effects and fate of succinic acid methyl esters in rat hepatocytes.
Topics: Amino Acids; Animals; Esters; Female; Gluconeogenesis; Glucose; Glycogen; Lactates; Lactic Acid; Liver; Oxidation-Reduction; Phosphorylation; Pyruvates; Pyruvic Acid; Rats; Succinates | 1994 |
Ouabain and digitoxin as modulators of chick embryo cardiomyocyte energy metabolism.
Topics: Animals; Caprylates; Cells, Cultured; Chick Embryo; Digitoxin; Energy Metabolism; Glucose; Glycolysis; Heart; Lactates; Lactic Acid; Muscle Proteins; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid | 1994 |
Energetic modulation of cardiac inotropism and sarcoplasmic reticular Ca2+ uptake.
Topics: Animals; Caffeine; Calcium; Calcium Radioisotopes; Energy Metabolism; Guinea Pigs; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Contraction; Phosphorylation; Pyruvates; Pyruvic Acid; Ryanodine; Sarcoplasmic Reticulum; Ventricular Function, Left | 1994 |
Capillary zone electrophoretic determination of organic acids in cerebrospinal fluid from patients with central nervous system diseases.
Topics: Brain Diseases; Cerebral Infarction; Electrophoresis; Humans; Lactates; Lactic Acid; Meningitis, Bacterial; Pyruvates; Pyruvic Acid; Spectrophotometry, Ultraviolet | 1994 |
Dynamics of energy metabolism in the transplanted human heart during reperfusion.
Topics: Energy Metabolism; Heart Transplantation; Heart-Lung Transplantation; Humans; Lactates; Lactic Acid; Myocardial Reperfusion; Myocardium; Pyruvates; Pyruvic Acid | 1994 |
Glucose, galactose, and glutamine metabolism in pig isolated enterocytes during development.
Topics: Animals; Animals, Newborn; Animals, Suckling; Female; Galactose; Glucose; Glutamine; Glycogen; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Kinetics; Lactates; Lactic Acid; Oxidation-Reduction; Pregnancy; Pyruvates; Pyruvic Acid; Swine | 1994 |
Effects of epidermal growth factor on gluconeogenesis and cellular redox state do not require Na+/H+ exchange or Na+/K(+)-ATPase activities.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amiloride; Animals; Cell Survival; Cells, Cultured; Epidermal Growth Factor; Gluconeogenesis; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Ouabain; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase | 1994 |
Glycogen synthesis from glucose by direct and indirect pathways in hepatocyte cultures from different nutritional states.
Topics: Albumins; Animals; Carbon Radioisotopes; Cells, Cultured; Glucokinase; Glucose; Glycogen; Insulin; Lactates; Lactic Acid; Liver; Male; Nutritional Status; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; RNA, Messenger; Tritium | 1994 |
Insulin stimulates glycolysis and pentose cycle activity in bovine microvascular endothelial cells.
Topics: Animals; Carbon Dioxide; Cattle; Cells, Cultured; Citric Acid Cycle; Coronary Vessels; Endothelium, Vascular; Glucose; Glycolysis; Insulin; Lactates; Lactic Acid; NADP; Nitric Oxide; Oxidation-Reduction; Pentoses; Pyruvates; Pyruvic Acid; Stereoisomerism | 1994 |
Serum serotonin, lactate and pyruvate levels in infantile autistic children.
Topics: Autistic Disorder; Child; Child, Preschool; Humans; Infant; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Reference Values; Serotonin | 1994 |
Exercise O2 transport model assuming zero cytochrome PO2 at VO2 max.
Topics: Anaerobiosis; Biological Transport, Active; Cytochromes; Exercise; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Models, Biological; Muscle, Skeletal; Myoglobin; Oxygen Consumption; Partial Pressure; Pyruvates; Pyruvic Acid; Regional Blood Flow | 1994 |
Generation of C3- and C2-deuterated L-lactic acid by human erythrocytes exposed to D-[1-13C]glucose, D-[2-13C]glucose and D-[6-13C]glucose in the presence of D2O.
Topics: Alanine; Alanine Transaminase; Carbon Isotopes; Deuterium; Erythrocytes; Glucose; Glycolysis; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvates; Pyruvic Acid | 1994 |
Glycolysis abnormalities in fibromyalgia.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Aging; Diphosphoglyceric Acids; Erythrocytes; Female; Fibromyalgia; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Growth Hormone; Humans; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Leukocytes; Male; Middle Aged; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Reference Values | 1994 |
Altered hepatic metabolic response to carbohydrate loads in rats with hepatic branch vagotomy or cholinergic blockade.
Topics: Animals; Atropine; Autonomic Nerve Block; Cholinergic Fibers; Fructose; Glucose; Glycogen; Glycolysis; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Vagotomy | 1994 |
Optimal handling of blood samples for routine measurement of lactate and pyruvate.
Topics: Adult; Blood Specimen Collection; Female; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Reproducibility of Results; Temperature; Time Factors | 1994 |
Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices.
Topics: Animals; Cell Size; Energy Metabolism; Glucose; Glycolysis; Hippocampus; Lactates; Lactic Acid; Membrane Potentials; Neurons; Pyruvates; Pyruvic Acid; Rats; Synaptic Transmission | 1994 |
Effect of concurrent exercise and physostigmine on lactate and pyruvate in plasma, muscle, and brain tissue of rats.
Topics: Animals; Brain; Kinetics; Lactates; Lactic Acid; Male; Muscles; Physical Exertion; Physostigmine; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1994 |
Possible role of cell redox state on collagen metabolism in carbon tetrachloride-induced cirrhosis as evidenced by adenosine administration to rats.
Topics: 3-Hydroxybutyric Acid; Adenosine; Animals; Carbon Tetrachloride; Collagen; Hydroxybutyrates; Lactates; Lactic Acid; Liver Cirrhosis, Experimental; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Measurement of pyruvate and lactate kinetics across the hindlimb and gut of anesthetized dogs.
Topics: Anesthesia; Animals; Dogs; Hindlimb; Intestinal Mucosa; Kinetics; Lactates; Lactic Acid; Models, Biological; Pyruvates; Pyruvic Acid | 1994 |
Effects of flow and contraction on lactate transport in the perfused rat hindlimb.
Topics: Animals; Biological Transport; Coumaric Acids; Electric Stimulation; Female; Lactates; Lactic Acid; Muscle Contraction; Muscles; Perfusion; Phloretin; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Nonglucose substrates increase glycogen synthesis in vivo in dog heart.
Topics: 3-Hydroxybutyric Acid; Animals; Carbon Isotopes; Dogs; Epinephrine; Glucose; Glycogen; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Oxygen Consumption; Pyruvates; Pyruvic Acid; Substrate Specificity | 1994 |
Mitochondrial creatine kinase activity in patients with disturbed energy generation in muscle mitochondria.
Topics: Adenosine Triphosphate; Adolescent; Adult; Child; Child, Preschool; Creatine Kinase; Energy Metabolism; Female; Humans; Infant; Lactates; Lactic Acid; Male; Mitochondria, Muscle; Mitochondrial Myopathies; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1994 |
Metabolic recovery of isolated working rat heart after brief global ischemia.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Fasting; Glucose-6-Phosphate; Glucosephosphates; Glycogen; Heart; Hydroxybutyrates; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Pyruvates; Pyruvic Acid; Rats; Time Factors | 1994 |
Plasma exchange and the arterial blood ketone body ratio in patients with acute hepatic failure.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Arteries; Child; Citrates; Citric Acid; Female; Humans; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Liver Failure, Acute; Male; Middle Aged; Plasma Exchange; Pyruvates; Pyruvic Acid; Survival Analysis | 1994 |
Type-2 astrocytes have much greater susceptibility to heat stress than type-1 astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cytosol; Heat-Shock Proteins; Hot Temperature; Lactates; Lactic Acid; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Stress, Physiological | 1994 |
Measured and predicted values of oxygen consumption during isoflurane anesthesia in man.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Anesthesia, Inhalation; Blood Glucose; Cardiac Output; Female; Hemoglobins; Humans; Isoflurane; Lactates; Lactic Acid; Male; Middle Aged; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Thermodilution | 1994 |
Substrate utilization by Rana ridibunda erythrocytes.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Diphosphoglyceric Acids; Erythrocytes; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Monosaccharides; Ouabain; Pyruvates; Pyruvic Acid; Rana ridibunda | 1994 |
Do the hydrolysis products, methylamine and N,N'-dimethylurea, play any role in the methyl isocyanate-induced haematological and biochemical changes in rabbits?
Topics: Animals; Antisickling Agents; Cyanates; Erythrocyte Count; Female; Hemoglobins; Hemorrhage; Hydrolysis; Isocyanates; Lactates; Lactic Acid; Lethal Dose 50; Leukocyte Count; Methylamines; Methylurea Compounds; Pyruvates; Pyruvic Acid; Rabbits; Serum Albumin; Urea | 1993 |
Odd-numbered medium-chain triglycerides (trinonanoin) in total parenteral nutrition: parameters of carbohydrate and protein metabolism.
Topics: Animals; Blood Glucose; Fat Emulsions, Intravenous; Glycogen; Lactates; Lactic Acid; Liver; Male; Nitrogen; Parenteral Nutrition, Total; Pyruvates; Pyruvic Acid; Rabbits; Triglycerides | 1993 |
Long-term monitoring of CSF lactate levels and lactate/pyruvate ratios following subarachnoid haemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Bicarbonates; Female; Humans; Hydrogen-Ion Concentration; Intracranial Aneurysm; Ischemic Attack, Transient; Lactates; Lactic Acid; Male; Middle Aged; Neurologic Examination; Pyruvates; Pyruvic Acid; Risk Factors; Subarachnoid Hemorrhage | 1993 |
The participation of energy substrates in the control of meiotic maturation in murine oocytes.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Energy Metabolism; Female; Glucose; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Ovarian Follicle; Pyruvates; Pyruvic Acid; Tricarboxylic Acids | 1994 |
Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats.
Topics: Acetyl Coenzyme A; Animals; Butyrates; Butyric Acid; Caprylates; Citrates; Citric Acid; Fatty Acids; Fructosediphosphates; Glycolysis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Toxicokinetics of diethylene glycol (DEG) in the rat.
Topics: Administration, Oral; Animals; Carbon Radioisotopes; Ethylene Glycols; Intestinal Absorption; Kidney; Lactates; Lactic Acid; Male; Metabolic Clearance Rate; Oxalates; Oxalic Acid; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1993 |
Indirect fluorescence determination of lactate and pyruvate in single erythrocytes by capillary electrophoresis.
Topics: Adult; Electrophoresis; Erythrocytes; Evaluation Studies as Topic; Fluorescein; Fluoresceins; Humans; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Spectrometry, Fluorescence | 1994 |
Alternatives to arginine as energy sources for the non-fermentative Mycoplasma gallinarum.
Topics: Acetoacetates; Arginine; Carboxylic Acids; Ethanol; Lactates; Lactic Acid; Mycoplasma; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1994 |
Acetaldehyde-protein adducts, but not lactate and pyruvate, stimulate gene transcription of collagen and fibronectin in hepatic fat-storing cells.
Topics: Acetaldehyde; Adipocytes; Animals; Collagen; Female; Fibronectins; Lactates; Lactic Acid; Liver; Proteins; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Transcription, Genetic | 1993 |
Metabolism of pyruvate by pre-elongation sheep embryos and effect of pyruvate and lactate concentrations during culture in vitro.
Topics: Animals; Blastocyst; Culture Media; Embryonic and Fetal Development; Female; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Male; Pregnancy; Pyruvates; Pyruvic Acid; Sheep | 1993 |
Pyruvate metabolism in Halobacterium salinarium studied by intracellular 13C nuclear magnetic resonance spectroscopy.
Topics: Alanine; Carbon Isotopes; Citric Acid Cycle; Halobacterium; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvates; Pyruvic Acid | 1994 |
Lactate-pyruvate interconversion in blood: implications for in vivo tracer studies.
Topics: Adult; Carbon Isotopes; Humans; Kinetics; Lactates; Lactic Acid; Male; Mass Spectrometry; Models, Biological; Osmolar Concentration; Pyruvates; Pyruvic Acid | 1994 |
Liver cytochrome c oxidase deficiency in a case of neonatal-onset hepatic failure.
Topics: Cytochrome-c Oxidase Deficiency; Female; Humans; Infant; Lactates; Lactic Acid; Liver; Liver Failure; Metabolism, Inborn Errors; Oxidative Phosphorylation; Pyruvates; Pyruvic Acid | 1994 |
Effect of lactate concentration and metabolic rate on net lactate uptake by canine skeletal muscle.
Topics: Animals; Dogs; Electric Stimulation; Female; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Male; Mathematics; Muscle Contraction; Muscles; Osmolar Concentration; Pyruvates; Pyruvic Acid | 1994 |
Influence of operation on glucose metabolism and lipolysis in human adipose tissue: a microdialysis study.
Topics: Adipose Tissue; Cholecystectomy; Female; Glucose; Humans; Insulin; Lactates; Lactic Acid; Lipolysis; Male; Microdialysis; Middle Aged; Pyruvates; Pyruvic Acid; Surgical Procedures, Operative | 1994 |
Metabolic and thermogenic effects of lactate infusion in humans.
Topics: Adult; Arteries; Blood; Blood Glucose; Body Temperature Regulation; Calorimetry, Indirect; Carbon Dioxide; Energy Metabolism; Fasting; Female; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Lactates; Lactic Acid; Male; Metabolism; Nitrogen; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1993 |
Alanine as a lipogenic precursor in isolated hepatocytes from obese Zucker rats.
Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Cells, Cultured; Citrates; Coumaric Acids; Fatty Acids; Glucose; Lactates; Lactic Acid; Leucine; Lipids; Liver; Liver Glycogen; Male; Mitochondria, Liver; Obesity; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker | 1993 |
The effects of exogenous lactate and pyruvate on the recovery of coronary flow in the rat heart after ischaemia.
Topics: Animals; Coronary Circulation; Glucose; In Vitro Techniques; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Lew; Time Factors | 1993 |
Energy metabolism of the trophectoderm and inner cell mass of the mouse blastocyst.
Topics: Animals; Blastocyst; Culture Techniques; Ectoderm; Energy Metabolism; Female; Glucose; Lactates; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Microscopy, Fluorescence; Pyruvates; Pyruvic Acid; Trophoblasts | 1993 |
Diltiazem preserves hepatic gluconeogenesis following hemorrhagic shock.
Topics: Animals; Diltiazem; Disease Models, Animal; Gluconeogenesis; Glucose; Isotonic Solutions; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Resuscitation; Ringer's Lactate; Shock, Hemorrhagic | 1993 |
Evidence for a preventive action of the vigilance-promoting drug modafinil against striatal ischemic injury induced by endothelin-1 in the rat.
Topics: Amphetamine; Animals; Arousal; Benzhydryl Compounds; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Endothelins; Hemodynamics; Injections; Lactates; Lactic Acid; Male; Microdialysis; Modafinil; Neostriatum; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Stereotyped Behavior | 1993 |
[Effect of gamma radiation on the concentration of pyruvate and lactate in erythrocytes of healthy men after submaximal physical exercise].
Topics: Adult; Erythrocytes; Exercise; Gamma Rays; Humans; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Reference Values | 1993 |
Lactated Ringer's solution alleviates brain trauma-precipitated lactic acidosis in hemorrhagic shock.
Topics: Acidosis, Lactic; Animals; Blood Glucose; Brain Injuries; Cerebral Hemorrhage; Gases; Hydrogen-Ion Concentration; Isotonic Solutions; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Resuscitation; Ringer's Lactate; Shock, Hemorrhagic | 1993 |
Accelerated glycolysis in early hypertensive left ventricular hypertrophy.
Topics: Animals; Blood Pressure; Energy Metabolism; Glycogen; Glycolysis; Hypertrophy, Left Ventricular; Lactates; Lactic Acid; Male; Myocardium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Function, Left | 1993 |
Energy economy in the pregnant human uterus at term: studies on arteriovenous differences in metabolites of carbohydrate, fat and nucleotides.
Topics: Adult; Arteries; Blood Glucose; Carbohydrates; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Lipids; Middle Aged; Nucleotides; Pregnancy; Pyruvates; Pyruvic Acid; Uterus; Veins; Xanthine; Xanthines | 1993 |
Radiosensitization of human lung fibroblasts by chemical that decrease ATP levels.
Topics: Adenosine Triphosphate; Cell Death; Cells, Cultured; Fibroblasts; Humans; Lactates; Lactic Acid; Lung; Nalidixic Acid; Novobiocin; Pyruvates; Pyruvic Acid; Radiation-Sensitizing Agents | 1993 |
Decreased hepatic glucose production in rats with carbon tetrachloride-induced cirrhosis.
Topics: Animals; Carbon Tetrachloride Poisoning; Glucagon; Gluconeogenesis; Glucose; Lactates; Lactic Acid; Liver; Liver Cirrhosis, Experimental; Male; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Urea | 1993 |
Mechanisms of glucose-enhanced extracellular matrix accumulation in rat glomerular mesangial cells.
Topics: Animals; Cell Division; Cells, Cultured; Collagen; DNA; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Fructose; Glomerular Mesangium; Glucose; Immunoenzyme Techniques; Inositol; Lactates; Lactic Acid; Laminin; Polymers; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1994 |
Specific enzymatic spectrophotometric assay of adenosine 5'-diphosphate.
Topics: Adenosine Diphosphate; Animals; Cattle; Cells, Cultured; Creatine Kinase; Endothelium, Vascular; Guanosine Diphosphate; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Phosphocreatine; Phosphorylation; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Spectrophotometry, Ultraviolet | 1993 |
Effects of phosphate, energy substrates, and amino acids on development of in vitro-matured, in vitro-fertilized bovine oocytes in a chemically defined, protein-free culture medium.
Topics: Amino Acids; Animals; Blastocyst; Cattle; Cells, Cultured; Culture Media; Energy Metabolism; Female; Fertilization in Vitro; Glucose; Lactates; Lactic Acid; Morula; Oocytes; Phosphates; Pyruvates; Pyruvic Acid | 1993 |
Inhibition of hepatic gluconeogenesis by niflumic acid correlates with the concentration of the free form.
Topics: Animals; Biological Availability; Gluconeogenesis; Glucose; Lactates; Lactic Acid; Liver; Male; Niflumic Acid; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Serum Albumin | 1993 |
Pyruvate and lactate metabolism in the in vivo dog heart.
Topics: Animals; Carbon Isotopes; Dogs; Energy Metabolism; Female; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Phosphates; Phosphorus; Pyruvates; Pyruvic Acid | 1993 |
The effect of metabolic fuel on force production and resting inorganic phosphate levels in mouse skeletal muscle.
Topics: Animals; Electric Stimulation; Glucose; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscles; Phosphates; Pyruvates; Pyruvic Acid | 1993 |
Characterisation of erythrocyte transmembrane exchange of trifluoroacetate using 19F-NMR: evidence for transport via the monocarboxylate transporter.
Topics: Animals; Anion Exchange Protein 1, Erythrocyte; Biological Transport; Cell Membrane Permeability; Coumaric Acids; Diffusion; Erythrocyte Membrane; Ethylmaleimide; Fluorides; Fluorine; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphoric Acids; Pyruvates; Pyruvic Acid; Sheep; Trifluoroacetic Acid | 1993 |
Responses to catecholamines in perfused livers of hypothalamic-lesioned rats.
Topics: Adrenalectomy; Animals; Catecholamines; Denervation; Glucagon; Glucose; Hypothalamus; Lactates; Lactic Acid; Liver; Male; Norepinephrine; Oxygen Consumption; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Vasopressins | 1993 |
Adenosine effect on lactate and pyruvate production in the hypoxic guinea pig heart.
Topics: Adenosine; Animals; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid | 1993 |
Glucose, pyruvate, and lactate concentrations in the blastocoel cavity of rat and mouse embryos.
Topics: Animals; Blastocyst; Body Fluids; Female; Fluorometry; Glucose; Lactates; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pregnancy; Punctures; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1993 |
Propionate regulates lymphocyte proliferation and metabolism.
Topics: Adult; Animals; B-Lymphocytes; Cells, Cultured; DNA; Glucose; Glutamine; Humans; Lactates; Lactic Acid; Lipids; Lymphocyte Activation; Lymphocytes; Male; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; T-Lymphocytes | 1993 |
Effect of sepsis on brain energy metabolism in normoxic and hypoxic rats.
Topics: Animals; Brain; Energy Metabolism; Female; Hypoxia; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sepsis | 1993 |
Adrenergic regulation of human adipose tissue metabolism in situ during mental stress.
Topics: Adipose Tissue; Adult; Blood Glucose; Dialysis; Epinephrine; Female; Glucose; Glycerol; Humans; Lactates; Lactic Acid; Lipolysis; Male; Norepinephrine; Phentolamine; Propranolol; Pyruvates; Pyruvic Acid; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stress, Psychological | 1993 |
Interrelationships between ureogenesis and gluconeogenesis in perfused rat liver.
Topics: Ammonium Chloride; Animals; Dichloroacetic Acid; Gluconeogenesis; Glucose; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Male; Oleic Acid; Oleic Acids; Ornithine; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Time Factors; Urea | 1993 |
Development of bovine embryos in vitro as affected by energy substrates.
Topics: Animals; Blastocyst; Calcium; Cattle; Culture Media; Culture Techniques; Embryonic and Fetal Development; Female; Fertilization in Vitro; Glucose; Lactates; Lactic Acid; Male; Morula; Pyruvates; Pyruvic Acid | 1993 |
Substrate-induced changes in the lipid content of ischemic and reperfused myocardium. Its relation to hemodynamic recovery.
Topics: Animals; Disease Models, Animal; Fatty Acids; Glucose; Glycerol; Heart; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardium; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Lew; Reperfusion Injury | 1993 |
The effects of tumor necrosis factor after removal of the gut.
Topics: Animals; Carbon Dioxide; Dogs; Female; Glucose; Hemodynamics; Intestines; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Tumor Necrosis Factor-alpha | 1993 |
Characterization of the inhibition by stilbene disulphonates and phloretin of lactate and pyruvate transport into rat and guinea-pig cardiac myocytes suggests the presence of two kinetically distinct carriers in heart cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Biological Transport; Carrier Proteins; Erythrocytes; Guinea Pigs; Kinetics; Lactates; Lactic Acid; Myocardium; Phloretin; Pyruvates; Pyruvic Acid; Rats; Stilbenes | 1993 |
Metabolic and hemodynamic effects of insulin on human hearts.
Topics: 3-Hydroxybutyric Acid; Coronary Circulation; Fatty Acids, Nonesterified; Female; Glycerol; Hemodynamics; Humans; Hydroxybutyrates; Insulin; Lactates; Lactic Acid; Male; Middle Aged; Myocardium; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1993 |
Ethanol alters the metabolic response of isolated perfused rat liver to a phagocytic stimulus.
Topics: Acetaldehyde; Animals; Blood Glucose; Culture Techniques; Endothelium, Vascular; Energy Metabolism; Ethanol; Fomepizole; Indomethacin; Kupffer Cells; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Oxygen Consumption; Perfusion; Phagocytosis; Prostaglandins; Pyrazoles; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1993 |
The mechanisms by which mild respiratory chain inhibitors inhibit hepatic gluconeogenesis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Diuron; Glucagon; Gluconeogenesis; Lactates; Lactic Acid; Liver; Mitochondria, Liver; Phenformin; Pyruvate Carboxylase; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Starvation | 1993 |
Dietary addition of cellular metabolic intermediates and carcass fat deposition in broilers.
Topics: Adipose Tissue; Animal Feed; Animals; Body Weight; Chickens; Citrates; Citric Acid; Dihydroxyacetone; Food, Fortified; Glycerol; Lactates; Lactic Acid; Liver; Male; Muscles; Organ Size; Pyruvates; Pyruvic Acid | 1993 |
Effect of acute hypoxia on metabolism and ventilation in awake piglets.
Topics: Animals; Carbon Dioxide; Hypoxia; Lactates; Lactic Acid; Oxygen; Oxygen Consumption; Pyruvates; Pyruvic Acid; Respiration; Respiratory Physiological Phenomena; Respiratory System; Swine; Wakefulness | 1993 |
The inhibitory action of buformin, a biguanide on gluconeogenesis from alanine and its transport system in rat livers.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Biological Transport, Active; Buformin; Cell Separation; Diabetes Mellitus, Experimental; Glucagon; Gluconeogenesis; Hydroxybutyrates; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Tolbutamide | 1993 |
Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Fructose; Glycolysis; Intracellular Membranes; Lactates; Lactic Acid; Liver; Male; Membrane Potentials; Mitochondria, Liver; Oligomycins; Oxidative Phosphorylation; Peroxides; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Trifluoperazine | 1993 |
Pattern of lactate production and steroidogenesis during growth and maturation of mouse ovarian follicles in vitro.
Topics: Animals; Energy Metabolism; Estradiol; Female; Follicle Stimulating Hormone; In Vitro Techniques; Lactates; Lactic Acid; Luteinizing Hormone; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Ovarian Follicle; Progesterone; Pyruvates; Pyruvic Acid | 1993 |
Biological variation of lactate and pyruvate in blood.
Topics: Adult; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1993 |
Time course of energy perturbation after compression trauma to the spinal cord: an experimental study in the rat using microdialysis.
Topics: Analysis of Variance; Animals; Dialysis; Energy Metabolism; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Spinal Cord; Spinal Cord Compression; Time Factors | 1993 |
Similar effects of ethanol and tert-butanol on amino acid concentrations in rat serum and liver.
Topics: Amino Acids; Animals; Butanols; Ethanol; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; tert-Butyl Alcohol | 1993 |
Partial oxidation of leucine in skeletal muscle.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diaphragm; Eating; Glucose; Hydroxybutyrates; Keto Acids; Ketone Bodies; Lactates; Lactic Acid; Leucine; Male; Muscles; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1993 |
Interaction of exercise and age on substrates of carbohydrate metabolism.
Topics: Aging; Animals; Blood Glucose; Carbohydrate Metabolism; Glycogen; Lactates; Lactic Acid; Male; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1993 |
Glycogenolytic and haemodynamic responses to bovine serum albumin in isolated perfused livers from sensitized rats.
Topics: Animals; Azepines; Calcium; Glycogen; Hemodynamics; Ibuprofen; In Vitro Techniques; Indomethacin; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Triazoles | 1993 |
A fatal, systemic mitochondrial disease with decreased mitochondrial enzyme activities, abnormal ultrastructure of the mitochondria and deficiency of heat shock protein 60.
Topics: Cells, Cultured; Female; Fibroblasts; Glucose; Heat-Shock Proteins; Humans; Infant, Newborn; Lactates; Lactic Acid; Microscopy, Electron; Mitochondria; Mitochondrial Encephalomyopathies; Pyruvates; Pyruvic Acid | 1993 |
Metformin decreases gluconeogenesis by enhancing the pyruvate kinase flux in isolated rat hepatocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Glucagon; Gluconeogenesis; Lactates; Lactic Acid; Liver; Male; Metformin; Perfusion; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1993 |
Metabolic effects of two regimens of growth hormone given before operation in piglets.
Topics: Animals; Calorimetry, Indirect; Energy Metabolism; Fatty Acids; Glucose; Growth Hormone; Lactates; Lactic Acid; Muscle, Skeletal; Nitrogen; Oxidation-Reduction; Postoperative Period; Preoperative Care; Pyruvates; Pyruvic Acid; Surgical Procedures, Operative; Swine; Time Factors; Triglycerides | 1995 |
Determination of lactate, pyruvate, beta-hydroxybutyrate and acetoacetate with a centrifugal analyser.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Age Factors; Blood Chemical Analysis; Centrifugation; Child; Child, Preschool; Humans; Hydroxybutyrates; Infant; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Reference Values; Reproducibility of Results; Temperature | 1995 |
Metabolic fluxes regulate the success of sporulation in Saccharomyces cerevisiae.
Topics: Acetates; Gluconeogenesis; Glyoxylates; Kinetics; Lactates; Lactic Acid; Meiosis; Oxygen Consumption; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Spores, Fungal | 1996 |
Utilization of acetic acid and other short-chain monocarboxylic acids in the yeasts Torulaspora delbrueckii and Saccharomyces cerevisiae: transport and its regulation.
Topics: Acetates; Acetic Acid; Biological Transport; Lactates; Lactic Acid; Propionates; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Saccharomycetales | 1994 |
A Cl channel in Ascaris suum selectivity conducts dicarboxylic anion product of glucose fermentation and suggests a role in removal of waste organic anions.
Topics: Action Potentials; Animals; Anions; Ascaris suum; Chloride Channels; Dicarboxylic Acids; Fermentation; Glucose; Lactates; Lactic Acid; Membrane Potentials; Patch-Clamp Techniques; Permeability; Pyruvates; Pyruvic Acid | 1995 |
Environment of the preimplantation human embryo in vivo: metabolite analysis of oviduct and uterine fluids and metabolism of cumulus cells.
Topics: Body Fluids; Cells, Cultured; Embryo Implantation; Embryo, Mammalian; Fallopian Tubes; Female; Glucose; Humans; Lactates; Lactic Acid; Oocytes; Pyruvates; Pyruvic Acid; Uterus | 1996 |
Lactate catabolism by enzyme-loaded red blood cells.
Topics: Acetates; Adenosine Triphosphate; Animals; Carbon Dioxide; Drug Compounding; Erythrocytes; Humans; Hydrogen Peroxide; In Vitro Techniques; Injections, Intraperitoneal; Lactates; Lactic Acid; Methemoglobin; Mice; Mixed Function Oxygenases; Pyruvates; Pyruvic Acid | 1995 |
The 8,344 mutation in mitochondrial DNA: a comparison between the proportion of mutant DNA and clinico-pathologic findings.
Topics: Adolescent; Adult; Base Sequence; Child; Child, Preschool; DNA Mutational Analysis; DNA, Mitochondrial; Electron Transport Complex IV; Female; Histocytochemistry; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondrial Encephalomyopathies; Molecular Sequence Data; Muscle, Skeletal; Phenotype; Polymerase Chain Reaction; Pyruvates; Pyruvic Acid | 1995 |
Experimental streptozotocin-reduced diabetes and intestinal glucose metabolism in the rat, in vivo and in vitro.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glycolysis; In Vitro Techniques; Intestine, Small; Lactates; Lactic Acid; Male; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Reference Values | 1995 |
Desulfitobacterium sp. strain PCE1, an anaerobic bacterium that can grow by reductive dechlorination of tetrachloroethene or ortho-chlorinated phenols.
Topics: Bacteria, Anaerobic; Biodegradation, Environmental; Chlorophenols; Culture Media; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Molecular Sequence Data; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Soil Microbiology; Temperature; Tetrachloroethylene | 1996 |
Effect of diet and training on muscle glycogen storage and utilization in sled dogs.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Diet; Dogs; Glycogen; Lactates; Lactic Acid; Muscle, Skeletal; Physical Conditioning, Animal; Pyruvates; Pyruvic Acid | 1995 |
Redox potential status in children with perinatal HIV-1 infection treated with zidovudine.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Child; Child, Preschool; Female; HIV Infections; HIV-1; Humans; Hydroxybutyrates; Infant; Infectious Disease Transmission, Vertical; Lactates; Lactic Acid; Male; Mitochondria; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Zidovudine | 1995 |
Derangement in aerobic and anaerobic energy metabolism in skeletal muscle of critically ill and recovering rats.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Creatine; Critical Illness; Energy Metabolism; Glycogen; Lactates; Lactic Acid; Male; Muscle, Skeletal; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Lew; Tricarboxylic Acids; Zymosan | 1996 |
Determination of lactic acid and pyruvic acid in serum and cerebrospinal fluid by ion-exclusion chromatography with a bulk acoustic wave detector.
Topics: Acoustics; Chromatography; Humans; Lactates; Lactic Acid; Phosphoric Acids; Pyruvates; Pyruvic Acid; Reference Values; Sensitivity and Specificity; Solutions | 1995 |
Clinical significance of serum hepatocyte growth factor in orthotopic liver transplantation.
Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Female; Hepatocyte Growth Factor; Humans; Lactates; Lactic Acid; Liver; Liver Circulation; Liver Transplantation; Male; Middle Aged; Osmolar Concentration; Postoperative Period; Pyruvates; Pyruvic Acid; Reperfusion; Survival Analysis | 1996 |
Muscle fatigue, lactate, and pyruvate in mitochondrial myopathy with progressive external ophthalmoplegia.
Topics: Action Potentials; Adolescent; Adult; Aged; Exercise Test; Female; Humans; Lactates; Lactic Acid; Male; Middle Aged; Mitochondrial Myopathies; Muscle Contraction; Muscle Fatigue; Ophthalmoplegia, Chronic Progressive External; Pyruvates; Pyruvic Acid | 1996 |
Pivalate affects carnitine status but causes no severe metabolic changes in rat liver.
Topics: 3-Hydroxybutyric Acid; Animals; Carnitine; Fatty Acids, Nonesterified; Gluconeogenesis; Heart; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Muscles; Myocardium; Pentanoic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1996 |
Mechanism of inhibition of hepatic gluconeogenesis by bacterial endotoxin: a role for nitric oxide?
Topics: Animals; Cells, Cultured; Cytokines; Gluconeogenesis; Lactates; Lactic Acid; Lipopolysaccharides; Liver; Nitric Oxide; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Pyruvic Acid; Shock, Septic | 1995 |
Protective effect of histidine by inhibition of gossypol on rat's liver LDH-5.
Topics: Animals; Fertility; Gossypol; Histidine; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats | 1995 |
Therapeutic efficacy of a case of pyruvate dehydrogenase complex deficiency monitored by localized proton magnetic resonance spectroscopy.
Topics: Brain; Brain Chemistry; Dichloroacetic Acid; Humans; Infant; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvates; Pyruvic Acid | 1996 |
Chloropropionic acid-induced alterations in glucose metabolic status: possible relevance to cerebellar granule cell necrosis.
Topics: Animals; Blood Glucose; Cerebellum; Cytoplasmic Granules; Glucose; Hydrocarbons, Chlorinated; Lactates; Lactic Acid; Male; Necrosis; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1995 |
Optimizing enzymatic cycling assays: spectrophotometric determination of low levels of pyruvate and L-lactate.
Topics: Animals; Biological Assay; Evaluation Studies as Topic; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mixed Function Oxygenases; Models, Chemical; Muscles; Pyruvates; Pyruvic Acid; Rabbits; Sensitivity and Specificity; Spectrophotometry | 1996 |
Effects of the nonsteroidal anti-inflammatory drug piroxicam on energy metabolism in the perfused rat liver.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimycin A; Atractyloside; Drug Interactions; Energy Metabolism; Fasting; Gluconeogenesis; Glucose; Glycogen; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxygen Consumption; Perfusion; Piroxicam; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1996 |
Carbohydrate metabolism in insulin resistance: glucose uptake and lactate production by adipose and forearm tissues in vivo before and after a mixed meal.
Topics: Adipose Tissue; Adult; Female; Forearm; Glucose; Humans; Insulin; Insulin Resistance; Lactates; Lactic Acid; Male; Middle Aged; Muscle, Skeletal; Obesity; Pyruvates; Pyruvic Acid; Regional Blood Flow | 1996 |
Intracellular lactate- and pyruvate-interconversion rates are increased in muscle tissue of non-insulin-dependent diabetic individuals.
Topics: Adult; Blood Glucose; Body Fluid Compartments; Diabetes Mellitus, Type 2; Forearm; Humans; Hyperglycemia; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Lipids; Male; Middle Aged; Models, Biological; Muscles; Pyruvates; Pyruvic Acid | 1996 |
In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated.
Topics: Acetyl Coenzyme A; Animals; Blood Chemical Analysis; Blood Glucose; Cholesterol; Deuterium; Deuterium Oxide; Fatty Acids; Gas Chromatography-Mass Spectrometry; Lactates; Lactic Acid; Liver; Male; Palmitates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Triglycerides | 1996 |
Oxygen uptake and carbohydrate metabolism by in vitro derived bovine embryos.
Topics: Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Cattle; Cells, Cultured; Culture Media; Embryo, Mammalian; Fertilization in Vitro; Glucose; Lactates; Lactic Acid; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1996 |
Effects of pyruvate and lactate on food intake in rat strains sensitive and resistant to dietary obesity.
Topics: Animals; Body Weight; Diet; Diet, Fat-Restricted; Dietary Fats; Eating; Lactates; Lactic Acid; Liver; Male; Obesity; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Species Specificity; Vagus Nerve | 1996 |
Mechanisms regulating the transport of acetic acid in Saccharomyces cerevisiae.
Topics: Acetates; Acetic Acid; Biological Transport; Carbohydrates; Carrier Proteins; Diffusion; Formates; Fungal Proteins; Lactates; Lactic Acid; Monocarboxylic Acid Transporters; Propionates; Protons; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae | 1996 |
Phagocytic function and metabolite production in thioacetamide-induced liver cirrhosis: a comparative study in perfused livers and cultured Kupffer cells.
Topics: Animals; Carbon; Colloids; Female; Glucose; Isoproterenol; Kupffer Cells; Lactic Acid; Liver; Liver Cirrhosis, Experimental; Phagocytes; Phagocytosis; Pyruvic Acid; Rats; Rats, Wistar; Thioacetamide; Zymosan | 1996 |
Progressive generalized brain atrophy and infantile spasms associated with cytochrome c oxidase deficiency.
Topics: Acidosis; Atrophy; Brain; Cytochrome-c Oxidase Deficiency; Humans; Infant, Newborn; Lactates; Lactic Acid; Magnetic Resonance Imaging; Male; Pyruvates; Pyruvic Acid; Spasms, Infantile | 1996 |
Response of phosphoenolpyruvate cycle activity to fasting and to hyperinsulinemia in human subjects.
Topics: Fasting; Humans; Hyperinsulinism; Lactic Acid; Male; Models, Biological; Oxaloacetates; Phosphoenolpyruvate; Pyruvic Acid | 1996 |
Microdialysis methodology for the measurement of dermal interstitial fluid in humans.
Topics: Adult; Biopsy; Calibration; Extracellular Space; Female; Glucose; Humans; Lactates; Lactic Acid; Male; Microdialysis; Pyruvates; Pyruvic Acid; Regional Blood Flow; Skin | 1996 |
Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle.
Topics: Adenosine Triphosphate; Animals; Caprylates; Citric Acid Cycle; Energy Metabolism; Glucose; Glycogen; In Vitro Techniques; Isometric Contraction; Lactates; Lactic Acid; Muscle, Smooth, Vascular; Oxygen Consumption; Phosphocreatine; Pyruvates; Pyruvic Acid; Substrate Specificity; Swine; Vasoconstriction | 1996 |
[The enzyme activity and pyruvate, lactate and 2,3-DPG levels in the erythrocytes of patients with severe forms of meningococcal infection and suppurative meningitis].
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Diphosphoglyceric Acids; Erythrocytes; Female; Humans; Lactic Acid; Male; Meningitis, Bacterial; Meningitis, Meningococcal; Meningitis, Pneumococcal; Meningococcal Infections; Middle Aged; Pyruvic Acid; Staphylococcal Infections; Time Factors | 1996 |
Anti-CD69 antibodies enhance phorbol-dependent glucose metabolism and Ca2+ levels in human thymocytes. Antagonist effect of cyclosporin A.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; Cyclosporine; Diglycerides; Drug Interactions; Fructosediphosphates; Glucose; Glycolysis; Humans; Immunosuppressive Agents; Lactates; Lactic Acid; Lectins, C-Type; Pyruvates; Pyruvic Acid; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymus Gland; Tritium | 1996 |
Progressive effect of endurance training on metabolic adaptations in working skeletal muscle.
Topics: Adaptation, Physiological; Adult; Citric Acid; Energy Metabolism; Glucose; Glucose-6-Phosphate; Glycogen; Humans; Lactic Acid; Male; Muscle, Skeletal; Phosphates; Physical Education and Training; Physical Endurance; Pyruvic Acid; Triglycerides | 1996 |
Sleeping time after phenobarbital treatment and the brain levels of gamma-aminobutyric acid and phenobarbital at the regaining of righting response point in ethionine-induced liver-disordered mice.
Topics: Anesthesia; Anesthesia Recovery Period; Animals; Brain Chemistry; Carcinogens; Chemical and Drug Induced Liver Injury; Ethionine; Female; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Lactic Acid; Liver Diseases; Mice; Phenobarbital; Pyruvic Acid; Sleep | 1996 |
Improvement of cardiac performance and metabolism in long-term diabetes mellitus after treatment with insulin [see comment].
Topics: Adenosine Triphosphate; Animals; Cardiac Output; Diabetes Mellitus, Experimental; Glucose; Heart; Insulin; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Phosphocreatine; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Time Factors | 1995 |
Complex I deficiency is associated with 3243G:C mitochondrial DNA in osteosarcoma cell cybrids.
Topics: Cell Fusion; DNA, Mitochondrial; Electron Transport Complex IV; Humans; Hybrid Cells; Lactates; Lactic Acid; MELAS Syndrome; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Osteosarcoma; Oxygen Consumption; Point Mutation; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Tumor Cells, Cultured | 1996 |
Effects of platelet-activating factor antagonist E5880 on intrahepatic and systemic metabolic responses to transient hepatic inflow occlusion and reperfusion in the rabbit.
Topics: 6-Ketoprostaglandin F1 alpha; Adenine Nucleotides; Ammonia; Analysis of Variance; Animals; Blood Gas Analysis; Blood Glucose; Energy Metabolism; Hydrogen-Ion Concentration; Lactic Acid; Liver; Male; Piperidines; Platelet Activating Factor; Pyridinium Compounds; Pyruvic Acid; Rabbits; Reperfusion Injury; Thromboxane B2 | 1996 |
Assay of the 13C and 2H mass isotopomer distribution of phosphoenolpyruvate by gas chromatography/mass spectrometry.
Topics: Animals; Borohydrides; Carbon Isotopes; Chromatography, Ion Exchange; Deuterium; Gas Chromatography-Mass Spectrometry; Glucose; In Vitro Techniques; Indicators and Reagents; Lactic Acid; Oxidation-Reduction; Perfusion; Peroxides; Phosphoenolpyruvate; Pyruvic Acid; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide | 1996 |
Elevated cerebrospinal fluid lactate/pyruvate ratio in Machado-Joseph disease.
Topics: Adult; Aged; Brain; Citric Acid Cycle; Female; Humans; Lactic Acid; Machado-Joseph Disease; Male; Middle Aged; Mitochondria; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Regional Blood Flow | 1996 |
High glycolysis in gliomas despite low hexokinase transcription and activity correlated to chromosome 10 loss.
Topics: Adenosine Triphosphate; Chromosome Deletion; Chromosomes, Human, Pair 10; Glioma; Glycolysis; Hexokinase; Humans; L-Lactate Dehydrogenase; Lactic Acid; Pyruvic Acid; RNA, Messenger | 1996 |
Characterization of Desulfitobacterium chlororespirans sp. nov., which grows by coupling the oxidation of lactate to the reductive dechlorination of 3-chloro-4-hydroxybenzoate.
Topics: Anaerobiosis; Bacteria, Anaerobic; Biodegradation, Environmental; Chlorine; Chlorobenzoates; Hydrogen-Ion Concentration; Hydroxybenzoates; Lactic Acid; Molecular Sequence Data; Oxidation-Reduction; Phylogeny; Pyruvic Acid; RNA, Ribosomal, 16S; Sequence Homology, Nucleic Acid; Soil Microbiology; Spores, Bacterial; Substrate Specificity; Temperature | 1996 |
Selectivity, differential mobility and resolution as parameters to optimize capillary electrophoretic separation.
Topics: Anions; Carboxylic Acids; Citric Acid; Computer Simulation; Electrolytes; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Isoelectric Point; Ketoglutaric Acids; Lactic Acid; Malates; Models, Chemical; Osmolar Concentration; Phosphates; Pyruvic Acid | 1996 |
The effect of erythropoietin on lactate, pyruvate and excess lactate under physical exercise in dialysis patients.
Topics: Anaerobic Threshold; Anemia; Case-Control Studies; Energy Metabolism; Erythropoietin; Exercise; Exercise Test; Female; Humans; Kidney Failure, Chronic; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid; Recombinant Proteins; Renal Dialysis | 1996 |
Metabolic assessment of wallaby blastocysts during embryonic diapause and subsequent reactivation.
Topics: Animals; Blastocyst; Glucose; Lactates; Lactic Acid; Macropodidae; Microscopy, Fluorescence; Pyruvates; Pyruvic Acid; Trophoblasts | 1995 |
Reduced glucose metabolism enhances the glutamate-evoked release of arachidonic acid from striatal neurons.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Lactic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Pyruvic Acid | 1996 |
Metabolism and cell allocation during parthenogenetic preimplantation mouse development.
Topics: Animals; Blastomeres; Cell Count; Chromosomes; Cleavage Stage, Ovum; Ectoderm; Embryonic and Fetal Development; Embryonic Development; Female; Glucose; Humans; Lactic Acid; Male; Metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mitosis; Parthenogenesis; Pregnancy; Pyruvic Acid | 1996 |
Age-related responses of right ventricle in swim-trained rats: changes in lactate and pyruvate contents and lactate dehydrogenase activity.
Topics: Aging; Anaerobiosis; Animals; Glycolysis; Hypertrophy, Right Ventricular; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardium; Organ Size; Physical Conditioning, Animal; Pyruvic Acid; Rats; Rats, Wistar; Swimming | 1996 |
Lipid-lowering drugs and mitochondrial function: effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio.
Topics: Adult; Aged; Enzyme Inhibitors; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lactic Acid; Male; Middle Aged; Mitochondria; Pyruvic Acid; Ubiquinone | 1996 |
Carbohydrate three-carbon metabolism of adipose tissue during surgery.
Topics: Adipose Tissue; Adult; Blood Glucose; Carbohydrate Metabolism; Cholecystectomy; Epinephrine; Female; Glucose; Humans; Insulin; Lactic Acid; Male; Norepinephrine; Pyruvic Acid | 1996 |
Microcalorimetric and biochemical investigations of thermogenesis and metabolic pathways in human white adipocytes.
Topics: Adipocytes; Adult; Aged; Body Temperature Regulation; Calorimetry; Cell Survival; Cells, Cultured; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Humans; Isoproterenol; L-Lactate Dehydrogenase; Lactic Acid; Lipolysis; Male; Middle Aged; Pyruvic Acid | 1996 |
Physiologic studies with the sulfate-reducing bacterium Desulfovibrio desulfuricans: evaluation for use in a biofuel cell.
Topics: Biomass; Cell Division; Desulfovibrio; Electricity; Hydrogen Sulfide; Kinetics; Lactic Acid; Models, Chemical; Oxidation-Reduction; Pyruvic Acid; Sulfates | 1996 |
Regulation of gonococcal sialyltransferase, lipooligosaccharide, and serum resistance by glucose, pyruvate, and lactate.
Topics: Aerobiosis; Anaerobiosis; Blood Bactericidal Activity; Culture Media; Cytidine Monophosphate N-Acetylneuraminic Acid; Glucose; Lactic Acid; Lipopolysaccharides; N-Acetylneuraminic Acid; Neisseria gonorrhoeae; Nitrites; Pyruvic Acid; Sialyltransferases | 1996 |
Hepatotoxic effects of SH-reagents in human and rat hepatocyte cultures and in situ perfused rat livers.
Topics: 2,2'-Dipyridyl; 4-Chloromercuribenzenesulfonate; Adenosine Triphosphate; Albumins; Alkylating Agents; Animals; Biotransformation; Cell Survival; Cells, Cultured; Chloromercuribenzoates; Disulfides; Disulfiram; Ethanol; Ethylmaleimide; Glycogen; Humans; Inactivation, Metabolic; Lactic Acid; Liver; Male; Mersalyl; Oxygen Consumption; p-Chloromercuribenzoic Acid; Pyruvic Acid; Rats; Rats, Wistar | 1996 |
Glucose production, recycling, and gluconeogenesis in normals and diabetics: a mass isotopomer [U-13C]glucose study.
Topics: Diabetes Mellitus, Type 2; Female; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Humans; Lactic Acid; Male; Middle Aged; Pyruvic Acid; Reference Values | 1996 |
Brain pyruvate oxidation in experimental thiamin-deficiency encephalopathy.
Topics: Alcohol Amnestic Disorder; Animals; Brain; Brain Chemistry; Female; Hypothalamus; Ketoglutarate Dehydrogenase Complex; Lactic Acid; Mesencephalon; Mitochondria; Oxygen Consumption; Pyrithiamine; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Substrate Specificity; Thalamus; Thiamine Deficiency; Time Factors; Wernicke Encephalopathy | 1996 |
Linkage of aerobic glycolysis to sodium-potassium transport in rat skeletal muscle. Implications for increased muscle lactate production in sepsis.
Topics: Aerobiosis; Alanine; Amino Acids; Animals; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Glycolysis; Hindlimb; Hydrogen-Ion Concentration; Lactic Acid; Lipopolysaccharides; Male; Monensin; Muscle, Skeletal; Ouabain; Potassium; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Shock, Septic; Sodium; Sodium-Potassium-Exchanging ATPase | 1996 |
Enhancement of glycolysis and CO2 formation from glycerol by hydroxyl radical scavengers in rat hepatocytes.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Dimethyl Sulfoxide; Free Radical Scavengers; Glucose; Glycerol; Glycolysis; Hydroxyl Radical; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Tromethamine | 1996 |
Hydroxycitrate causes altered pyruvate metabolism by tumorigenic cells.
Topics: Animals; ATP Citrate (pro-S)-Lyase; Carbon Dioxide; Cell Line; Citrates; Citric Acid; Citric Acid Cycle; Glucose; Humans; Lactic Acid; Neoplasms; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Tumor Cells, Cultured | 1996 |
Cadmium-sensitive targets in the aerobic respiratory metabolism of Staphylococcus aureus.
Topics: Aerobiosis; Cadmium; Cell Membrane; Culture Media; Cytoplasm; Glutamic Acid; Lactic Acid; Mixed Function Oxygenases; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxidoreductases; Pyruvic Acid; Staphylococcus aureus | 1996 |
Effects of thoracic epidural anesthesia on changes in ischemic myocardial metabolism induced by intracoronary injection of endothelin in dogs.
Topics: Adenosine Triphosphate; Anesthesia, Epidural; Animals; Coronary Circulation; Dogs; Endothelins; Female; Lactic Acid; Male; Myocardial Ischemia; Myocardium; Pyruvic Acid | 1996 |
Effects of glutamate and aspartate on myocardial substrate oxidation during potassium arrest.
Topics: Acetoacetates; Animals; Aspartic Acid; Carbon Radioisotopes; Citric Acid Cycle; Fatty Acids; Glucose; Glutamic Acid; Heart; Heart Arrest, Induced; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Oxygen Consumption; Potassium; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1996 |
Blood lactate and pyruvate concentrations, and their ratio during exercise in healthy children: developmental perspective.
Topics: Adolescent; Aging; Child; Child Development; Female; Humans; Lactic Acid; Male; Osmolar Concentration; Oxygen Consumption; Physical Exertion; Pyruvic Acid | 1995 |
[Lactate determination at rest and during bicycle ergometry in healthy probands and in patients with mitochondrial myopathies].
Topics: Electron Transport; Exercise Test; Glycolysis; Humans; Lactic Acid; Mitochondrial Myopathies; Pyruvic Acid; Reference Values | 1996 |
Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: the roles of endogenous pyruvate and lactate. Relevance to inflammatory joint diseases.
Topics: Adult; Aged; Arthritis; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Knee Joint; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyruvic Acid; Synovial Fluid | 1997 |
Age-related ischemia in the brain following bilateral carotid artery occlusion--collateral blood flow and brain metabolism.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Suckling; Arterial Occlusive Diseases; Brain; Brain Ischemia; Carotid Artery Diseases; Cerebellum; Collateral Circulation; Functional Laterality; Lactic Acid; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Subclavian Steal Syndrome | 1997 |
Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes.
Topics: 3-Hydroxybutyric Acid; 3-O-Methylglucose; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Energy Metabolism; Enzyme Inhibitors; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Hydroxybutyrates; Insulin; Lactic Acid; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Phenylephrine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substrate Specificity; Transaminases | 1997 |
Increased lactate/pyruvate ratio with normal beta-hydroxybutyrate/acetoacetate ratio and lack of oxygen supply dependency in a patient with fatal septic shock.
Topics: Acetoacetates; Aged; Fatal Outcome; Hemodynamics; Humans; Hydroxybutyrates; Lactic Acid; Male; Oxygen; Oxygen Consumption; Pyruvic Acid; Shock, Septic | 1997 |
Use of labeling pattern of liver glutamate to calculate rates of citric acid cycle and gluconeogenesis.
Topics: Animals; Citric Acid Cycle; Dichloroacetic Acid; Enzyme Inhibitors; Glucagon; Gluconeogenesis; Glutamic Acid; Lactic Acid; Liver; Methods; Osmolar Concentration; Picolinic Acids; Pyruvate Kinase; Pyruvic Acid; Rats | 1997 |
Regulation of synthesis of pyruvate carboxylase in the photosynthetic bacterium Rhodobacter capsulatus.
Topics: Aerobiosis; Amino Acid Sequence; Anaerobiosis; Chloramphenicol; Citric Acid Cycle; Culture Media; Darkness; Dicarboxylic Acids; Enzyme Induction; Enzyme Repression; Fumarates; Lactic Acid; Molecular Sequence Data; Protein Synthesis Inhibitors; Pyruvate Carboxylase; Pyruvic Acid; Rhodobacter capsulatus | 1997 |
In vivo functional investigations of lactic acid in patients with respiratory chain disorders.
Topics: Adolescent; Adult; Age of Onset; Case-Control Studies; Child; Child, Preschool; Creatinine; Electron Transport; Humans; Infant; Lactic Acid; Metabolism, Inborn Errors; Middle Aged; Pyruvic Acid; Retrospective Studies | 1997 |
Comparison of the lactate-pyruvate ratio during labour and delivery in singleton and twin pregnancy.
Topics: Female; Fetal Blood; Humans; Labor, Obstetric; Lactic Acid; Oxygen Consumption; Pregnancy; Pregnancy, Multiple; Pyruvic Acid; Twins | 1997 |
Effect of glucose and pyruvate in acidic and non-acidic peritoneal dialysis fluids on leukocytes cell functions.
Topics: Cell Line; Chemotaxis, Leukocyte; Cytokines; Dialysis Solutions; Glucose; Humans; In Vitro Techniques; Lactic Acid; Leukocytes; Leukocytes, Mononuclear; Macrophages, Peritoneal; Peritoneal Dialysis, Continuous Ambulatory; Pyruvic Acid; Reactive Oxygen Species; RNA, Messenger | 1997 |
Effects of copper, iron and fluoride co-crystallized with sugar on caries development and acid formation in deslivated rats.
Topics: Acetates; Acids; Animals; Butyrates; Cariogenic Agents; Cariostatic Agents; Colony Count, Microbial; Copper; Crystallization; Dental Caries; Dental Plaque; Disease Models, Animal; Drug Synergism; Female; Fluorides; Iron; Isobutyrates; Lactic Acid; Mouth; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Saliva; Salivary Glands; Streptococcus sobrinus; Sucrose | 1996 |
Effect of high glucose on permeability of retinal capillary endothelium in vitro.
Topics: Animals; Blood-Retinal Barrier; Capillary Permeability; Carbon Radioisotopes; Cattle; Cells, Cultured; Diffusion Chambers, Culture; Electric Impedance; Endothelium, Vascular; Enzyme Inhibitors; Fructose; Glucose; Guanidines; Inulin; Lactic Acid; Phthalazines; Polymers; Pyruvic Acid; Retinal Vessels; Sorbitol | 1997 |
The acetate kinase of Clostridum acetobutylicum strain P262.
Topics: Acetate Kinase; Acetates; Chromatography, Agarose; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Clostridium; Electrophoresis, Polyacrylamide Gel; Fermentation; Glucose; Hydrogen-Ion Concentration; Lactic Acid; NAD; Phosphate Acetyltransferase; Phosphotransferases (Carboxyl Group Acceptor); Pyruvic Acid | 1996 |
Hepatic glucose production from L-alanine is absent in perfused liver of diabetic rats.
Topics: Alanine; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glycerol; Infusions, Intravenous; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Software; Sorbitol; Streptozocin | 1997 |
The effects of propofol on cerebral high energy metabolites, lactate, and glucose in normoxic and severely hypoxic rats.
Topics: Adenine Nucleotides; Anesthetics, Intravenous; Animals; Cerebral Cortex; Energy Metabolism; Glucose; Hypoxia; Lactic Acid; Male; Oxygen; Phosphocreatine; Propofol; Pyruvic Acid; Rats; Rats, Inbred F344 | 1997 |
[The Ohtahara's syndrome: a special form of age-dependent epilepsy].
Topics: Adrenocorticotropic Hormone; Age of Onset; Ammonia; Brain; Electroencephalography; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; Male; Pyruvic Acid; Retrospective Studies; Syndrome | 1997 |
Gonadotropins, serum, and amino acids alter nuclear maturation, cumulus expansion, and oocyte morphology in hamster cumulus-oocyte complexes in vitro.
Topics: Actin Cytoskeleton; Amino Acids; Animals; Blood Proteins; Cattle; Cell Nucleus; Cricetinae; Culture Media; Female; Follicle Stimulating Hormone; Glucose; Glutamine; In Vitro Techniques; Lactic Acid; Luteinizing Hormone; Mesocricetus; Oocytes; Pyruvic Acid | 1997 |
Differential regulation of glucose and glycogen metabolism in vascular smooth muscle by exogenous substrates.
Topics: Acetates; Animals; Carbon Isotopes; Carotid Arteries; Glucose; Glycogen; Isometric Contraction; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Muscle Contraction; Muscle, Smooth, Vascular; Pyruvic Acid; Swine | 1997 |
Identification of a unique monocarboxylate transporter (MCT3) in retinal pigment epithelium.
Topics: Amino Acid Sequence; Animals; Biological Transport; Carrier Proteins; Cell Line; Chickens; Cloning, Molecular; DNA, Complementary; Gene Expression; Glycosylation; Lactic Acid; Membrane Transport Proteins; Microscopy, Fluorescence; Molecular Sequence Data; Pigment Epithelium of Eye; Protons; Pyruvic Acid; Rats; RNA, Messenger; Sequence Homology, Amino Acid; Transfection | 1997 |
Microdialysis of human breast tissue during the menstrual cycle.
Topics: Adipose Tissue; Adult; Amino Acids; Asparagine; Aspartic Acid; Breast; Chromatography, High Pressure Liquid; Female; Glycine; Humans; Lactic Acid; Menstrual Cycle; Microdialysis; Ornithine; Pyruvic Acid; Serine; Threonine; Tyrosine | 1997 |
Insulin and insulin-like growth factor 1 antagonize the stimulation of ob gene expression by dexamethasone in cultured rat adipose tissue.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Animals; Cyclic AMP; Cycloheximide; Dexamethasone; Energy Metabolism; Enzyme Induction; Epididymis; Fatty Acid Synthases; Fatty Acids; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Leptin; Male; Microbodies; Monosaccharide Transport Proteins; Muscle Proteins; Organ Culture Techniques; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
[Effects of steroids on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acidosis, Lactic; Acute Disease; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Glycogen; Hemorrhage; Hydrocortisone; Lactic Acid; Liver; Male; Methylprednisolone; Pyruvic Acid; Rats; Rats, Wistar | 1997 |
Metabolism of lactate by mature boar spermatozoa.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Fructose; Glucose; Glycerol; Glycerophosphates; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Spermatozoa; Swine | 1997 |
Effects of pyruvate-based or lactate-based peritoneal dialysis solutions on neutrophil intracellular pH.
Topics: Adult; Biocompatible Materials; Dialysis Solutions; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Neutrophils; Peritoneal Dialysis; Pyruvic Acid | 1997 |
Renal circulation and cellular metabolism during left ventricular assisted circulation: comparison study of pulsatile and nonpulsatile assists.
Topics: Animals; beta 2-Microglobulin; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Erythrocytes; Heart Failure; Heart-Assist Devices; Ketone Bodies; Kidney; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Kidney Tubules; Lactic Acid; Microcirculation; Pulsatile Flow; Pyruvic Acid; Renal Circulation; Shock, Cardiogenic; Swine; Ventricular Function, Left | 1997 |
Types and sources of fuels for platelets in a medium containing minimal added fuels and a low carryover plasma.
Topics: Adenosine Triphosphate; Amino Acids; Ammonia; Blood Platelets; Blood Preservation; Culture Media; Glycogen; Humans; Lactic Acid; Lipid Metabolism; Oxygen; Oxygen Consumption; Pyruvic Acid | 1997 |
A case of Leber's hereditary optic neuropathy with elevated blood levels of lactate and pyruvate.
Topics: Adult; Humans; Lactic Acid; Male; Optic Atrophies, Hereditary; Pyruvic Acid | 1997 |
Inhibition of glycerol metabolism in hepatocytes isolated from endotoxic rats.
Topics: Adenine Nucleotides; Animals; Caprylates; Cell Membrane Permeability; Cells, Cultured; Dihydroxyacetone Phosphate; Endotoxemia; Gluconeogenesis; Glycerol; Glycerophosphates; Lactic Acid; Lipopolysaccharides; Liver; Male; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar | 1997 |
Hemodynamic effects of isoprostanes (8-iso-prostaglandin F2alpha and E2) in isolated guinea pig hearts.
Topics: Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Coronary Circulation; Dinoprost; Dinoprostone; Endothelin-1; F2-Isoprostanes; Fatty Acids, Unsaturated; Guinea Pigs; Heart Rate; Hemodynamics; Hydrazines; In Vitro Techniques; Isoprostanes; Lactic Acid; Male; Myocardial Contraction; Myocardium; Pyruvic Acid; Receptors, Thromboxane; Vasoconstrictor Agents | 1997 |
The purpose of glycolysis.
Topics: Alanine; Animals; Brain; Cerebrovascular Circulation; Cytosol; Glycolysis; Humans; Lactic Acid; Neurons; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid | 1997 |
Effect of low levels of fluoride on proton excretion and intracellular pH in glycolysing streptococcal cells under strictly anaerobic conditions.
Topics: Anaerobiosis; Bacteriological Techniques; Fluorides; Glucose; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Proton-Translocating ATPases; Protons; Pyruvic Acid; Streptococcus mutans | 1997 |
Control of the shift from homolactic acid to mixed-acid fermentation in Lactococcus lactis: predominant role of the NADH/NAD+ ratio.
Topics: Acetyltransferases; Fermentation; Galactose; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Lactococcus lactis; Lactose; NAD; Pyruvic Acid | 1997 |
Formation of formate and hydrogen, and flux of reducing equivalents and carbon in Ruminococcus flavefaciens FD-1.
Topics: Acetates; Anaerobiosis; Bacterial Proteins; Carbon Dioxide; Cellobiose; Cellulose; Fermentation; Formates; Gram-Positive Cocci; Hydrogen; Hydrogen-Ion Concentration; Hydrogenase; Lactic Acid; Phosphoenolpyruvate; Pyruvic Acid; Succinic Acid | 1997 |
Activation of pyruvate dehydrogenase improves heart function and metabolism after hemorrhagic shock.
Topics: Adenosine Triphosphate; Animals; Arteries; Blood Chemical Analysis; Blood Pressure; Dichloroacetic Acid; Energy Metabolism; Heart; Hemodynamics; Lactic Acid; Male; Myocardium; Phosphates; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Ventricular Function | 1997 |
Glycogen utilization and ischemic injury in the isolated rat heart.
Topics: Animals; Creatine Kinase; Fasting; Glycogen; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Ischemia; Myocardium; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1997 |
Influence of different levels of redox potential on fermentative products formed by Bacteroides fragilis.
Topics: Acetic Acid; Bacteroides fragilis; Fermentation; Lactic Acid; Oxidation-Reduction; Pyruvic Acid; Succinic Acid | 1997 |
Dexfenfluramine modulates hepatic glycogen metabolism by a calcium-dependent pathway.
Topics: Adrenergic Agonists; Adrenergic alpha-Agonists; Animals; Calcium; Enzyme Activation; Epinephrine; Fenfluramine; Fructosediphosphates; Glucose; Lactic Acid; Liver; Liver Glycogen; Male; Phenylephrine; Phosphorylases; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Glucose response elements in a gene that codes for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Topics: Animals; Carcinoma, Hepatocellular; Dactinomycin; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes; Glucose; Insulin; Lactic Acid; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phosphofructokinase-2; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Promoter Regions, Genetic; Pyruvic Acid; Rats; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tumor Cells, Cultured; Xylitol | 1997 |
Pyruvate protects neurons against hydrogen peroxide-induced toxicity.
Topics: Animals; Butyrates; Cells, Cultured; Corpus Striatum; Energy Metabolism; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ketoglutaric Acids; Lactic Acid; Mice; Neurons; Neuroprotective Agents; Oxaloacetates; Oxidation-Reduction; Oxidative Stress; Pyruvic Acid; Vitamin K | 1997 |
Determination of the specific radioactivity of [14C]lactate by enzymatic decarboxylation and 14CO2 collection.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Decarboxylation; Kinetics; Lactic Acid; Mixed Function Oxygenases; Pyruvate Oxidase; Pyruvic Acid; Rabbits; Reproducibility of Results; Scintillation Counting; Temperature; Tissue Extracts | 1997 |
New familial mitochondrial encephalopathy with macrocephaly, cardiomyopathy, and complex I deficiency.
Topics: Cardiomyopathies; Electrophoresis, Gel, Two-Dimensional; Family Health; Fatal Outcome; Fibroblasts; Head; Humans; Infant; Lactic Acid; Male; Mitochondrial Encephalomyopathies; Muscle Fibers, Skeletal; Muscle, Skeletal; Myocardium; NAD(P)H Dehydrogenase (Quinone); Nuclear Family; Phenotype; Pyruvic Acid | 1997 |
Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation.
Topics: Animals; Biological Transport; Cell Communication; Coumaric Acids; Cytochalasin B; Electrophysiology; Energy Metabolism; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; Iodoacetates; Iodoacetic Acid; Lactic Acid; Neuroglia; Neurons; Organ Culture Techniques; Pyruvic Acid; Rats; Rats, Inbred Strains; Synapses | 1997 |
Pyruvate improves deleterious effects of high glucose on activation of pentose phosphate pathway and glutathione redox cycle in endothelial cells.
Topics: Adenosine Triphosphate; Cells, Cultured; Endothelium, Vascular; Fructosediphosphates; Glucose; Glutathione; Humans; Hydrogen Peroxide; Lactic Acid; NAD; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvic Acid; Umbilical Veins | 1997 |
Mixed venous oxygen saturation and biochemical parameters of hypoxia during progressive hypoxemia in 10- to 14-day-old piglets.
Topics: Animals; Disease Progression; Hypoxia; Lactic Acid; Linear Models; Oxygen; Pyruvic Acid; Swine; Veins | 1997 |
Dynamic 13C NMR analysis of pyruvate and lactate oxidation in the in vivo canine myocardium: evidence of reduced utilization with increased work.
Topics: Animals; Carbon Radioisotopes; Citric Acid Cycle; Dichloroacetic Acid; Dogs; Glutamic Acid; Heart; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Oxidation-Reduction; Pyruvic Acid | 1997 |
Pentoxifylline induces hyperactivation and acrosome reaction in spermatozoa of golden hamsters: changes in motility kinematics.
Topics: Acrosome; Animals; Cricetinae; Culture Media; Female; Isotonic Solutions; Kinetics; Lactic Acid; Male; Mesocricetus; Pentoxifylline; Polyvinyl Alcohol; Pyruvic Acid; Serum Albumin, Bovine; Sperm Motility; Spermatozoa | 1997 |
Effect of methotrexate (MTX) on NAD(P)+ dehydrogenases of HeLa cells: malic enzyme, 2-oxoglutarate and isocitrate dehydrogenases.
Topics: Antimetabolites, Antineoplastic; HeLa Cells; Humans; Isocitrate Dehydrogenase; Ketoglutarate Dehydrogenase Complex; Lactic Acid; Malate Dehydrogenase; Methotrexate; Mitochondria; NADPH Dehydrogenase; Oxidoreductases; Oxygen Consumption; Pyruvic Acid | 1997 |
Cerebral metabolic changes in biotinidase deficiency.
Topics: Amidohydrolases; Biotin; Biotinidase; Brain; Electroencephalography; Humans; Infant; Lactic Acid; Magnetic Resonance Imaging; Male; Pyruvic Acid; Seizures; Valerates | 1997 |
Mitochondrial respiratory chain succinate-cytochrome-c oxidoreductase deficiency and hepatic cirrhosis.
Topics: Electron Transport; Fatal Outcome; Humans; Infant; Lactic Acid; Liver; Liver Cirrhosis; Male; Mitochondria; Pyruvic Acid; Succinate Cytochrome c Oxidoreductase | 1997 |
Human tubal fluid: production, nutrient composition and response to adrenergic agents.
Topics: Adrenergic beta-Agonists; Adult; Animals; Body Fluids; Cattle; Cyclic AMP; Fallopian Tubes; Female; Glucose; Humans; Isoproterenol; Lactic Acid; Middle Aged; Perfusion; Pyruvic Acid | 1997 |
Phosphoenolpyruvate prevents the decline in hepatic ATP and energy charge after ischemia and reperfusion injury in rats.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Arteries; Energy Metabolism; Infusions, Intravenous; Ischemia; Kinetics; Lactic Acid; Liver; Male; Phosphoenolpyruvate; Portal Vein; Pyruvic Acid; Rats; Rats, Wistar; Reperfusion Injury | 1997 |
Functional evidence for a monocarboxylate transporter (MCT) in strial marginal cells and molecular evidence for MCT1 and MCT2 in stria vascularis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Base Sequence; Carrier Proteins; Coumaric Acids; Cricetinae; Cytosol; DNA, Complementary; Electrophoresis, Agar Gel; Gerbillinae; Hydrogen-Ion Concentration; Lactic Acid; Membrane Proteins; Molecular Sequence Data; Monocarboxylic Acid Transporters; Polymerase Chain Reaction; Pyruvic Acid; RNA; Sequence Homology, Nucleic Acid; Stria Vascularis | 1997 |
Lactate formation from [U-13C]aspartate in cultured astrocytes: compartmentation of pyruvate metabolism.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Enzyme Inhibitors; Immunohistochemistry; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Phosphoenolpyruvate Carboxykinase (ATP); Pyruvic Acid | 1997 |
Pyruvate augments calcium transients and cell shortening in rat ventricular myocytes.
Topics: Animals; Calcium; Cells, Cultured; Cytosol; Glucose; Heart; Heart Ventricles; Lactic Acid; Male; Mitochondria, Heart; Models, Cardiovascular; Myocardial Contraction; Myocardium; NAD; NADP; Phosphorylation; Pyruvic Acid; Rats; Rats, Wistar | 1998 |
Status of ammonia, glutamate, lactate and pyruvate during Plasmodium yoelii infection and pyrimethamine treatment in mice.
Topics: Ammonia; Animals; Antimalarials; Glutamic Acid; Humans; Lactic Acid; Malaria; Mice; Plasmodium yoelii; Pyrimethamine; Pyruvic Acid | 1997 |
Effect of chronic ethanol consumption on respiratory and glycolytic activities of rat periportal and perivenous hepatocytes.
Topics: Adenosine Triphosphate; Alcohol Drinking; Anaerobiosis; Animals; Ascorbic Acid; Cell Respiration; Cells, Cultured; Ethanol; Glucosyltransferases; Glycogen; Glycolysis; Glycoproteins; Lactic Acid; Liver; Male; Mice; NAD; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1998 |
Expression of the monocarboxylate transporter MCT2 by rat brain glia.
Topics: Animals; Antibody Specificity; Astrocytes; Brain Chemistry; Carrier Proteins; DNA, Complementary; Immunoblotting; Immunohistochemistry; Kidney; Lactic Acid; Membrane Proteins; Microscopy, Electron; Monocarboxylic Acid Transporters; Muscle, Skeletal; Neuropil; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sequence Analysis, DNA; Stomach | 1998 |
[Effects of lactated Ringer solution and acetated Ringer solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acute Disease; Adenosine Triphosphate; Animals; Glycogen; Hemorrhage; Isotonic Solutions; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Ringer's Lactate | 1998 |
Lactate transport in L6 skeletal muscle cells and vesicles: allosteric or multisite mechanism and functional membrane marker of differentiation.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Allosteric Regulation; Animals; Biological Transport; Cell Line; Cell Membrane; Citric Acid; Coumaric Acids; Creatine Kinase; Kinetics; Lactic Acid; Muscle, Skeletal; Phenylmercury Compounds; Pyruvic Acid; Rats; Sarcolemma; Succinic Acid | 1998 |
Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Enzyme Inhibitors; Gossypol; Humans; Isoelectric Point; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; NAD; Plasmodium falciparum; Pyruvic Acid; Recombinant Proteins; Substrate Specificity | 1997 |
Plasma lactic acid and pyruvic acid levels in migraine and tension-type headache.
Topics: Adult; Energy Metabolism; Female; Humans; Lactic Acid; Male; Middle Aged; Migraine Disorders; Mitochondria; Pyruvic Acid; Tension-Type Headache | 1998 |
Redox potential measurements of plasma in patients undergoing coronary artery bypass graft and its clinical significance.
Topics: Anticoagulants; Aprotinin; Aspirin; Coronary Artery Bypass; Electrophysiology; Heparin; Heparin Antagonists; Homeostasis; Humans; Intraoperative Complications; Lactic Acid; Oxidants; Oxidation-Reduction; Oxidative Stress; Plasma; Protamines; Pyruvic Acid; Serine Proteinase Inhibitors | 1997 |
A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.
Topics: Animals; Cell Line; Dihydroxyacetone Phosphate; Drug Synergism; Fatty Acids; Glucose; Glycerophosphates; Glycolysis; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Lactic Acid; Male; Malonyl Coenzyme A; Mitochondria; Proinsulin; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1998 |
High oxygen delivery and extraction by perfluorocarbon-primed extracorporeal membrane oxygenation do not prevent anaerobic metabolism in rabbits.
Topics: Anaerobiosis; Animals; Carbon Dioxide; Extracorporeal Membrane Oxygenation; Fluorocarbons; Hematocrit; Hydroxyethyl Starch Derivatives; Lactic Acid; Male; Oxygen; Partial Pressure; Pyruvic Acid; Rabbits | 1998 |
Vanadium toxicology--an assessment of general health, haematological aspects and energy response in an Indian catfish Clarias batrachus (Linn).
Topics: Anaerobiosis; Animals; Catfishes; Energy Metabolism; Environmental Monitoring; Hematocrit; Hemoglobins; India; Lactic Acid; Liver; Liver Glycogen; Muscle, Skeletal; Pyruvic Acid; Vanadium; Water Pollutants, Chemical | 1998 |
Metabolism of pyruvate by the early human embryo.
Topics: Acrylates; Biological Transport; Culture Media; Culture Techniques; Embryo, Mammalian; Glucose; Humans; Lactic Acid; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid | 1998 |
The importance of the glycerol 3-phosphate shuttle during aerobic growth of Saccharomyces cerevisiae.
Topics: Aerobiosis; Ethanol; Glycerol; Glycerol-3-Phosphate Dehydrogenase (NAD+); Glycerolphosphate Dehydrogenase; Glycerophosphates; Hydrogen-Ion Concentration; Isoenzymes; Lactic Acid; Mutation; NAD; NADH Dehydrogenase; Oxidation-Reduction; Pyruvic Acid; Saccharomyces cerevisiae | 1998 |
Markers of cellular dysoxia during orthotopic liver transplantation in pigs.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Biomarkers; Carnitine; Cell Hypoxia; Cytosol; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Humans; Hydroxybutyrates; Lactic Acid; Liver Transplantation; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; ROC Curve; Swine; Time Factors | 1998 |
Vestibular dark cells contain an H+/monocarboxylate- cotransporter in their apical and basolateral membrane.
Topics: 4-Chloromercuribenzenesulfonate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Animals; Carrier Proteins; Cell Membrane; Coumaric Acids; Cricetinae; Dicarboxylic Acids; Electrophysiology; Gerbillinae; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Polymerase Chain Reaction; Pyruvic Acid; Vestibule, Labyrinth | 1998 |
Changes in the redox state in the retina and brain during the onset of diabetes in rats.
Topics: Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; L-Lactate Dehydrogenase; Lactic Acid; Lens, Crystalline; Liver; NAD; Oxidation-Reduction; Pigment Epithelium of Eye; Pyruvic Acid; Rats; Retina | 1998 |
The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patients.
Topics: Blood Glucose; C-Peptide; Calorimetry, Indirect; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Dicarboxylic Acids; Fatty Acids, Nonesterified; Humans; Insulin; Ketone Bodies; Kinetics; Lactic Acid; Middle Aged; Oxygen Consumption; Pyruvic Acid | 1998 |
Pantothenol protects rats against some deleterious effects of gamma radiation.
Topics: Animals; Antioxidants; beta Carotene; Cholesterol; Coenzyme A; Drug Administration Schedule; Female; Gamma Rays; Glutathione; Glutathione Disulfide; Intubation, Gastrointestinal; Lactic Acid; Lipids; Liver; Malate Dehydrogenase; Malate Dehydrogenase (NADP+); NAD; Pantothenic Acid; Phospholipids; Proteins; Pyruvic Acid; Radiation-Protective Agents; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances | 1998 |
Effect of glucagon on the plasma concentration of uridine.
Topics: Adult; Blood Glucose; Cyclic AMP; Glucagon; Humans; Lactic Acid; Male; Middle Aged; Osmolar Concentration; Phosphates; Purines; Pyruvic Acid; Uridine | 1998 |
Xylitol-induced increase in the plasma concentration and urinary excretion of uridine and purine bases.
Topics: Adult; Humans; Hypoxanthine; Injections, Intravenous; Lactic Acid; Male; Middle Aged; Osmolar Concentration; Phosphates; Purines; Pyruvic Acid; Uric Acid; Uridine; Xanthine; Xylitol | 1998 |
Conditions that promote production of lactic acid by Zymomonas mobilis in batch and continuous culture.
Topics: Carbon Dioxide; Culture Media; Ethanol; Fermentation; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Pentose Phosphate Pathway; Plasmids; Pyruvic Acid; Salts; Zymomonas | 1998 |
Control of oxidative phosphorylation, gluconeogenesis, ureagenesis and ATP turnover in isolated perfused rat liver analyzed by top-down metabolic control analysis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Ammonia; Amobarbital; Animals; Gluconeogenesis; Glucose; Hydroxybutyrates; Lactic Acid; Liver; Oxidative Phosphorylation; Oxygen Consumption; Perfusion; Pyruvic Acid; Quinolinic Acid; Rats; Urea; Valine | 1998 |
Metabolism of [3-(13)C]-pyruvate by cysticerci of Taenia crassiceps.
Topics: Acetates; Alanine; Animals; Citric Acid; Citric Acid Cycle; Cysticercus; Cytosol; Lactic Acid; Magnetic Resonance Spectroscopy; Malate Dehydrogenase; Mitochondria; Pyruvic Acid; Succinic Acid | 1998 |
AACC 50th anniversary retrospective. Citation classics in intermediary metabolism. American Association for Clinical Chemistry.
Topics: Calcium; Chemistry, Clinical; Clinical Laboratory Techniques; Glucose; History, 20th Century; Humans; Lactic Acid; Metabolism; Periodicals as Topic; Pyruvic Acid; Urea | 1998 |
In vivo voltammetric detection of rat brain lactate with carbon fiber microelectrodes coated with lactate oxidase.
Topics: Animals; Biosensing Techniques; Brain; Carbon; Carbon Fiber; Cellulose; Electrochemistry; Electrodes, Implanted; Hydrogen Peroxide; Lactic Acid; Male; Microelectrodes; Mixed Function Oxygenases; Pyruvic Acid; Rats | 1998 |
[Standardized bicycle ergometry test in mitochondrial myopathies. Indications, interferences and clinical parameters].
Topics: Adult; Energy Metabolism; Exercise Test; Female; Humans; Isometric Contraction; Lactic Acid; Male; Middle Aged; Mitochondrial Myopathies; Pyruvic Acid; Reference Values; Sensitivity and Specificity; Ubiquinone | 1998 |
Hyperpolarization of the cell membrane of mouse hepatocytes by lactate, pyruvate, and fructose is due to Ca2+-dependent activation of K+ channels and of the Na+/K+-ATPase.
Topics: Amiloride; Animals; Calcium; Cell Membrane; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; Female; Fructose; Gluconeogenesis; Lactic Acid; Liver; Mice; Mice, Inbred ICR; Ouabain; Potassium Channel Blockers; Potassium Channels; Pyruvic Acid; Sodium-Potassium-Exchanging ATPase; Tetraethylammonium; Thapsigargin | 1998 |
Extracellular ischaemia markers in repeated global ischaemia and secondary hypoxaemia monitored by microdialysis in rat brain.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Electroencephalography; Energy Metabolism; Extracellular Space; Hypoxanthine; Hypoxia, Brain; Inosine; Ischemic Attack, Transient; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1998 |
Comparative effects of englitazone and glyburide on gluconeogenesis and glycolysis in the isolated perfused rat liver.
Topics: Animals; Benzopyrans; Dihydroxyacetone; Fructose; Gluconeogenesis; Glucose; Glyburide; Glycerol; Glycolysis; Hypoglycemic Agents; In Vitro Techniques; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones | 1998 |
Clinical application of the measurement of cord plasma lactate and pyruvate in the assessment of high-risk neonates.
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Infant, Premature; Lactic Acid; Male; Pyruvic Acid; Risk Assessment; Sensitivity and Specificity | 1998 |
Insulin stimulates pyruvate dehydrogenase and protects human ventricular cardiomyocytes from simulated ischemia.
Topics: Adenine Nucleotides; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; Insulin; Lactic Acid; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 1998 |
Oxidative phosphorylation in intact hepatocytes: quantitative characterization of the mechanisms of change in efficiency and cellular consequences.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphatases; Adenosine Triphosphate; Almitrine; Animals; Caprylates; Cells, Cultured; Dihydroxyacetone; Lactic Acid; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Proton Pumps; Pyruvic Acid; Rats; Rats, Wistar; Thermodynamics | 1998 |
Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum.
Topics: Animals; Enzyme Inhibitors; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; NAD; Oxidation-Reduction; Plasmodium falciparum; Pyruvic Acid; Sesquiterpenes | 1998 |
Interference with cellular energy metabolism reduces kynurenic acid formation in rat brain slices: reversal by lactate and pyruvate.
Topics: Animals; Brain; Electron Transport; Energy Metabolism; Formazans; Glucose; In Vitro Techniques; Kynurenic Acid; Kynurenine; Lactic Acid; Male; Neurons; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tetrazolium Salts | 1998 |
Effect of increased cardiac output on liver blood flow, oxygen exchange and metabolic rate during longterm endotoxin-induced shock in pigs.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiac Output; Gluconeogenesis; Hemodynamics; Hemoglobins; Lactic Acid; Liver; Liver Circulation; Oxygen Consumption; Pyruvic Acid; Shock, Septic; Swine; Time Factors | 1998 |
Lactate, lactate/pyruvate ratio and catecholamine interrelations in cord blood at delivery in complicated pregnancies.
Topics: Asphyxia Neonatorum; Catecholamines; Female; Fetal Blood; Humans; Infant, Newborn; Labor, Obstetric; Lactic Acid; Pregnancy; Pregnancy Complications; Pyruvic Acid | 1998 |
Simulated postaggression metabolism in healthy subjects: metabolic changes and insulin resistance.
Topics: Adult; Carbohydrate Metabolism; Fatty Acids, Nonesterified; Humans; Insulin Resistance; Lactic Acid; Male; Pyruvic Acid; Stress, Physiological | 1998 |
Human embryo culture: back to nature.
Topics: Amino Acids; Body Fluids; Calcium; Chlorine; Culture Media; Electron Probe Microanalysis; Fallopian Tubes; Female; Glucose; Humans; Lactic Acid; Magnesium; Male; Oxygen; Phosphorus; Potassium; Pregnancy; Pyruvic Acid; Serum Albumin; Sodium; Sulfur | 1998 |
Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter.
Topics: Amino Acid Sequence; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 12; Cloning, Molecular; DNA, Complementary; Humans; Lactic Acid; Molecular Sequence Data; Monocarboxylic Acid Transporters; Protein Binding; Pyruvic Acid; RNA, Messenger; Sequence Homology, Amino Acid; Tumor Cells, Cultured | 1998 |
Lactate and pyruvate changes in the cerebral gray and white matter during posthypoxic seizures in newborn pigs.
Topics: Animals; Animals, Newborn; Cerebellum; Electroencephalography; Hypoxia; Lactic Acid; Microdialysis; Pyruvic Acid; Seizures; Swine; Time Factors | 1998 |
[Effects of local ischemia on various parameters of the small intestine viability at different ages].
Topics: Age Factors; Animals; Catalase; Dogs; Hemorrhage; Intestine, Small; Ischemia; L-Lactate Dehydrogenase; Lactic Acid; Lipid Peroxidation; Malondialdehyde; Mesentery; Microcirculation; Pyruvic Acid; Superoxide Dismutase | 1998 |
Interleukin 1alpha stimulates lactate dehydrogenase A expression and lactate production in cultured porcine sertoli cells.
Topics: Animals; Blotting, Northern; Cells, Cultured; Gene Expression; Glucose; Interleukin-1; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Pyruvic Acid; RNA, Messenger; Sertoli Cells; Swine | 1998 |
Pyruvate prevents hydrogen peroxide-induced apoptosis.
Topics: Acetates; Animals; Annexin A5; Apoptosis; Cell Membrane; Cell Size; Cell Survival; Cells, Cultured; DNA Fragmentation; Flow Cytometry; Hydrogen Peroxide; Lactic Acid; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Phosphatidylserines; Propidium; Pyruvic Acid; T-Lymphocytes; Thymus Gland | 1998 |
Changes in rectal temperature and hematologic, biochemical, blood gas, and acid-base values in healthy Labrador Retrievers before and after strenuous exercise.
Topics: Acid-Base Equilibrium; Animals; Blood Cell Count; Blood Chemical Analysis; Blood Gas Analysis; Body Temperature; Dogs; Female; Lactic Acid; Male; Physical Conditioning, Animal; Pulse; Pyruvic Acid; Reference Values; Respiration | 1999 |
Spinal muscular atrophy-like picture, cardiomyopathy, and cytochrome c oxidase deficiency.
Topics: Blotting, Western; Cardiomegaly; Cells, Cultured; Cytochrome-c Oxidase Deficiency; Fibroblasts; Humans; Infant, Newborn; Lactic Acid; Male; Mitochondria; Pyruvic Acid; Spinal Muscular Atrophies of Childhood | 1999 |
Neurochemical monitoring of fatal middle cerebral artery infarction.
Topics: Adult; Biomarkers; Brain Edema; Cerebral Arteries; Cerebral Cortex; Cerebral Infarction; Fatal Outcome; Female; Follow-Up Studies; Glutamic Acid; Glycerol; Humans; Lactic Acid; Microdialysis; Pyruvic Acid; Tomography, X-Ray Computed | 1999 |
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate.
Topics: Adenine Nucleotides; Animals; Capillary Permeability; Deoxyglucose; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Osmolar Concentration; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Metabolic effects of oxalate in the perfused rat liver.
Topics: Alanine; Animals; Ascorbic Acid; Gluconeogenesis; Glycolysis; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Liver Glycogen; Male; Oxalic Acid; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Wistar | 1998 |
[Effects of hypertonic lactated Ringer's solution on hepatic ATP and L/P ratio in rats subjected to acute hemorrhage].
Topics: Acute Disease; Adenosine Triphosphate; Animals; Energy Metabolism; Glycogen; Hemorrhage; Hypertonic Solutions; Isotonic Solutions; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Ringer's Lactate | 1998 |
Does growth hormone augment brain edema caused by brain injury? A study with a freeze brain injury model in the rat.
Topics: Animals; Blood Glucose; Body Water; Brain Chemistry; Brain Edema; Brain Injuries; Disease Models, Animal; Drug Evaluation, Preclinical; Freezing; Human Growth Hormone; Injections, Subcutaneous; Insulin; Lactic Acid; Male; Muscle, Skeletal; Pyruvic Acid; Rats; Rats, Wistar; Sodium | 1999 |
Rapid on-line microdialysis hyphenated technique for the dynamic monitoring of extracellular pyruvate, lactic acid and ascorbic acid during cerebral ischemia.
Topics: Animals; Ascorbic Acid; Brain Ischemia; Extracellular Space; Gerbillinae; Lactic Acid; Microdialysis; Pyruvic Acid; Reproducibility of Results | 1999 |
Kinetics of lactate and pyruvate transport in cultured rat myotubes.
Topics: Animals; Biological Transport; Carrier Proteins; Cell Differentiation; Cells, Cultured; Creatine Kinase; Fluoresceins; Fluorescent Dyes; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Muscle, Skeletal; Protein Isoforms; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Repopulation of rho0 cells with mitochondria from a patient with a mitochondrial DNA point mutation in tRNA(Gly) results in respiratory chain dysfunction.
Topics: Blotting, Southern; Cardiomyopathy, Hypertrophic; Citrate (si)-Synthase; DNA, Mitochondrial; Electron Transport; Electron Transport Complex II; Electron Transport Complex III; Fibroblasts; Glycine; Humans; Hybrid Cells; Lactic Acid; Models, Genetic; Multienzyme Complexes; NADH Dehydrogenase; Oxidoreductases; Phenotype; Point Mutation; Pyruvic Acid; Quinone Reductases; RNA, Transfer, Gly; Succinate Dehydrogenase | 1999 |
Lipid storage myopathy in a cocker spaniel.
Topics: Acetoacetates; Animals; Dog Diseases; Dogs; Lactic Acid; Lipid Metabolism, Inborn Errors; Male; Muscle, Skeletal; Muscular Diseases; Pyruvic Acid | 1999 |
Uptake and excretion of sodium taurocholate by the isolated perfused neonatal sheep liver.
Topics: Aging; Algorithms; Animals; Animals, Newborn; Bile; Blood Pressure; Lactic Acid; Liver; Liver Circulation; Oxygen Consumption; Perfusion; Pyruvic Acid; Sheep; Taurocholic Acid | 1999 |
Major organ function under mechanical support: comparative studies of pulsatile and nonpulsatile circulation.
Topics: Animals; Blood Circulation; Cerebrovascular Circulation; Heart-Assist Devices; Hemodynamics; Ketone Bodies; Lactic Acid; Liver Circulation; Microcirculation; Myocardial Infarction; Prosthesis Design; Pulsatile Flow; Pyruvic Acid; Renal Circulation; Shock, Cardiogenic; Swine | 1999 |
Energy storage and cytokine response in patients undergoing liver transplantation.
Topics: Adolescent; Adult; Aged; Cytokines; Energy Metabolism; Humans; Interleukin-1; Interleukin-6; Ketone Bodies; Lactic Acid; Liver Glycogen; Liver Transplantation; Middle Aged; Muscles; Pyruvic Acid; Tumor Necrosis Factor-alpha | 1999 |
S(+)-ketamine, but not R(-)-ketamine, reduces postischemic adherence of neutrophils in the coronary system of isolated guinea pig hearts.
Topics: Anesthetics, Dissociative; Animals; Cell Adhesion; Coronary Vessels; Guinea Pigs; Humans; Ketamine; Lactic Acid; Macrophage-1 Antigen; Male; Myocardial Ischemia; Neutrophils; Nitric Oxide; Nitroarginine; Pyruvic Acid; Stereoisomerism | 1999 |
Carbon and electron flow in Clostridium cellulolyticum grown in chemostat culture on synthetic medium.
Topics: Acetates; Adenosine Triphosphate; Bacteriological Techniques; Biomass; Carbon; Cellobiose; Clostridium; Coenzymes; Culture Media; Diffusion; Electron Transport; Ethanol; Glycolysis; Hydrogen; Kinetics; Lactic Acid; Oxidation-Reduction; Oxidoreductases; Pyruvic Acid; Salts | 1999 |
Regulation of NO-elicited pulmonary artery relaxation and guanylate cyclase activation by NADH oxidase and SOD.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Catalase; Cattle; Colforsin; Cyclic GMP; Endothelium, Vascular; Estradiol; Guanylate Cyclase; Lactic Acid; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Nitric Oxide; Oxidation-Reduction; Penicillamine; Pulmonary Artery; Pyruvic Acid; Superoxide Dismutase; Superoxides; Vasodilation | 1999 |
Modifications of citric acid cycle activity and gluconeogenesis in streptozotocin-induced diabetes and effects of metformin.
Topics: Animals; Citric Acid Cycle; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glutamic Acid; Hypoglycemic Agents; In Vitro Techniques; Lactic Acid; Liver; Male; Metformin; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Starvation; Streptozocin | 1999 |
The toxic and metabolic effects of 23 aliphatic alcohols in the isolated perfused rat liver.
Topics: 3,4-Methylenedioxyamphetamine; Adenosine Triphosphate; Alanine Transaminase; Alcohols; Animals; Bile; Glutamate Dehydrogenase; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; Oxidation-Reduction; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Solubility; Structure-Activity Relationship | 1999 |
A general method for relieving substrate inhibition in lactate dehydrogenases.
Topics: Enzyme Inhibitors; Escherichia coli; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Mutagenesis, Site-Directed; Myocardium; NAD; Pyruvic Acid | 1999 |
Study of single-molecule dynamics and reactions with classic light microscopy.
Topics: Bacteriophage lambda; Deoxyribonucleases, Type II Site-Specific; DNA, Viral; L-Lactate Dehydrogenase; Lactic Acid; Microinjections; Microscopy, Fluorescence; NAD; NADP; Pyruvic Acid | 1999 |
Frequency-dependent fatigue development during electrical stimulation in the masseter muscle of pigtail monkeys.
Topics: Animals; Bite Force; Electric Stimulation; Electromyography; Female; Glucose; Glycogen; Lactic Acid; Macaca nemestrina; Male; Masseter Muscle; Muscle Fatigue; NAD; Phosphocreatine; Pyruvic Acid | 1998 |
Influence of deflated and anaerobic conditions during cold storage on rat lungs.
Topics: Air; Anaerobiosis; Animals; Bronchoalveolar Lavage Fluid; Cryopreservation; Lactic Acid; Lung; Male; Nitrogen; Organ Preservation; Phosphates; Pulmonary Alveoli; Pyruvic Acid; Rats; Rats, Inbred Lew; Reperfusion Injury; Respiration, Artificial; Risk Factors | 1999 |
Brain substrate utilisation during acute hypoglycaemia.
Topics: Acute Disease; Adult; Amino Acids; Blood Glucose; Brain; Glucose Clamp Technique; Humans; Hypoglycemia; Lactic Acid; Male; Pyruvic Acid | 1999 |
Cytosolic redox state mediates postischemic response to pyruvate dehydrogenase stimulation.
Topics: Animals; Cytosol; Heart; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rabbits | 1999 |
Relationship between mixed venous oxygen saturation and markers of tissue oxygenation in progressive hypoxic hypoxia and in isovolemic anemic hypoxia in 8- to 12-day-old piglets.
Topics: Anemia; Animals; Animals, Newborn; Hemoglobins; Hypoxia; Lactic Acid; Oximetry; Oxygen; Oxygen Consumption; Pyruvic Acid; Reference Values; Swine; Veins | 1999 |
Pyruvate and lactate protect striatal neurons against N-methyl-D-aspartate-induced neurotoxicity.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cytosol; Energy Metabolism; Excitatory Amino Acid Agonists; Free Radical Scavengers; Glucose; Glutamic Acid; Glycolysis; Kinetics; Lactic Acid; Mice; Mitochondria; N-Methylaspartate; Neostriatum; Neurons; Neurotoxicity Syndromes; Oxygen Consumption; Pyruvic Acid | 1999 |
Regulation of the lipopolysaccharide-specific sialyltransferase activity of gonococci by the growth state of the bacteria, but not by carbon source, catabolite repression or oxygen supply.
Topics: Carbon; Cytidine Monophosphate N-Acetylneuraminic Acid; Glucose; Lactic Acid; Lipopolysaccharides; Neisseria gonorrhoeae; Oxygen; Pyruvic Acid; Sialyltransferases | 1999 |
Effect of induced metabolic acidosis on human skeletal muscle metabolism during exercise.
Topics: Acidosis; Adult; Exercise; Fatty Acids, Nonesterified; Glycerol; Glycogen; Humans; Lactic Acid; Leg; Male; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Phosphates; Pulmonary Gas Exchange; Pyruvic Acid; Regional Blood Flow | 1999 |
The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis.
Topics: Adenosine Triphosphate; Animals; Epinephrine; Glucagon; Glucose; Glycolysis; Homeostasis; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Liver Glycogen; Mitochondria, Liver; Models, Biological; NAD; Protons; Pyruvic Acid; Rats | 1999 |
Contributions of dietary carbohydrate and ethanol to alterations in liver glycogen levels and glycolytic activity.
Topics: Animals; Central Nervous System Depressants; Dietary Carbohydrates; Ethanol; Glycolysis; Lactic Acid; Liver Glycogen; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1999 |
Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Brain Ischemia; Cerebral Cortex; Female; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Point-of-Care Systems; Postoperative Complications; Prognosis; Pyruvic Acid; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 1999 |
Cardiac and skeletal muscle mitochondria have a monocarboxylate transporter MCT1.
Topics: Amino Acid Sequence; Animals; Antibodies; Blotting, Western; Carrier Proteins; Cell Membrane; Glucose Transporter Type 1; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Microscopy, Electron; Mitochondria, Muscle; Molecular Sequence Data; Monocarboxylic Acid Transporters; Monosaccharide Transport Proteins; Muscle, Skeletal; Myocardium; Myofibrils; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sarcolemma | 1999 |
Glucoregulation during and after intense exercise: effects of beta-adrenergic blockade in subjects with type 1 diabetes mellitus.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinephrine; Exercise; Fatty Acids, Nonesterified; Glycerol; Homeostasis; Humans; Insulin; Insulin Secretion; Lactic Acid; Male; Norepinephrine; Oxygen Consumption; Propranolol; Pyruvic Acid; Receptors, Adrenergic, beta | 1999 |
Regulation of skeletal muscle glycogen phosphorylase and PDH during maximal intermittent exercise.
Topics: Acetylcarnitine; Adenosine Triphosphate; Adult; Coenzyme A; Energy Metabolism; Exercise Test; Glycolysis; Humans; Lactic Acid; Male; Muscle, Skeletal; Oxidative Phosphorylation; Phosphocreatine; Phosphorylases; Physical Exertion; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 1999 |
Effects of insulin and metformin on glucose metabolism in rat vascular smooth muscle.
Topics: Acetyl Coenzyme A; Animals; Glucose; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Mitochondria, Muscle; Muscle, Smooth, Vascular; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1999 |
The in vitro manipulation of carbohydrate metabolism: a new strategy for deciphering the cellular defence mechanisms against nitric oxide attack.
Topics: Adenosine Triphosphate; Carbohydrate Metabolism; Cell Survival; Culture Media; Deoxyglucose; Epithelial Cells; Galactose; Glucose; Glutathione; HT29 Cells; Humans; Lactic Acid; Nitric Oxide; Nitroso Compounds; Oligomycins; Pyruvic Acid; S-Nitrosoglutathione; Tyrosine | 1999 |
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells.
Topics: Adenoviridae; Animals; Carrier Proteins; Cell Line; Fluoresceins; Fluorescent Antibody Technique; Gene Expression Regulation; Glucose; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; L-Lactate Dehydrogenase; Lactic Acid; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Transfection | 1999 |
Gluconeogenesis in the liver of arthritic rats.
Topics: Alanine; Animals; Arthritis, Experimental; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Oxygen; Pyruvic Acid; Rats; Rats, Wistar; Xylitol | 1999 |
Red blood cell energy metabolism during cardiopulmonary bypass.
Topics: Adenine Nucleotides; Aged; Body Temperature; Cardiopulmonary Bypass; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Coronary Disease; Energy Metabolism; Erythrocytes; Female; Hematocrit; Hemoglobins; Humans; Hydrogen-Ion Concentration; Lactic Acid; Male; Middle Aged; Pyruvic Acid | 1999 |
Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.
Topics: Animals; Blastocyst; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Fluorescence; Glucose; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; NAD; Oxidation-Reduction; Pregnancy; Pyruvic Acid; Zygote | 2000 |
Altered glutamate metabolism is associated with reduced muscle glutathione levels in patients with emphysema.
Topics: Biomarkers; Body Mass Index; Female; Glutamic Acid; Glutathione; Glycolysis; Humans; Lactic Acid; Male; Muscle, Skeletal; Pulmonary Emphysema; Pyruvic Acid; Respiratory Function Tests | 2000 |
A model analysis of lactate accumulation during muscle ischemia.
Topics: Computer Simulation; Glycolysis; Humans; Ischemia; Lactic Acid; Models, Biological; Muscles; Oxidation-Reduction; Oxygen; Pyruvic Acid; Regional Blood Flow; Time Factors | 1999 |
Sevoflurane and isoflurane do not enhance the pre- and postischemic eicosanoid production in guinea pig hearts.
Topics: Anesthetics, Inhalation; Animals; Coronary Circulation; Dinoprost; Eicosanoids; Guinea Pigs; Hemodynamics; In Vitro Techniques; Isoflurane; Lactic Acid; Male; Methyl Ethers; Myocardial Ischemia; Myocardium; Pyruvic Acid; Sevoflurane; Thromboxane A2; Time Factors | 2000 |
Neonatal hypoglycaemia in Nepal 2. Availability of alternative fuels.
Topics: Age Factors; Blood Glucose; Cross-Sectional Studies; Energy Metabolism; Fatty Acids, Nonesterified; Female; Fever; Glycerol; Humans; Hydroxybutyrates; Hyperinsulinism; Hypoglycemia; Infant Nutritional Physiological Phenomena; Infant, Low Birth Weight; Infant, Newborn; Infant, Small for Gestational Age; Ketones; Lactic Acid; Male; Nepal; Pyruvic Acid; Regression Analysis; Risk Factors; Sex Factors; Stress, Physiological; Thyroid Hormones; Thyroxine | 2000 |
Effect of hypocapnea on CBF and extracellular intermediates of secondary brain injury.
Topics: Brain; Brain Injuries; Carbon Dioxide; Chromatography, High Pressure Liquid; Extracellular Space; Glasgow Coma Scale; Glutamic Acid; Hematoma, Subdural; Humans; Hyperventilation; Hypocapnia; Intracranial Pressure; Lactic Acid; Microdialysis; Pyruvic Acid; Time Factors | 1999 |
Continuous monitoring of cerebrospinal fluid acid-base balance and oxygen metabolism in patients with severe head injury: pathophysiology and treatments for cerebral acidosis and ischemia.
Topics: Acidosis; Adolescent; Adult; Brain Injuries; Brain Ischemia; Carbon Dioxide; Fever; Glasgow Coma Scale; Humans; Hyperventilation; Jugular Veins; Lactic Acid; Middle Aged; Monitoring, Physiologic; Oxygen; Postoperative Care; Pyruvic Acid | 1999 |
[Parameters of energy metabolism in patients after vascular reconstructive surgical procedures].
Topics: Acid-Base Equilibrium; Adult; Antioxidants; Energy Metabolism; Female; Humans; Ischemia; Lactic Acid; Leg; Male; Middle Aged; Oxidation-Reduction; Pyruvic Acid; Reperfusion Injury; Vascular Surgical Procedures | 1999 |
A pyruvate-proton symport and an H+-ATPase regulate the intracellular pH of Trypanosoma brucei at different stages of its life cycle.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acid-Base Equilibrium; Animals; Blood; Carrier Proteins; Chlorides; Coumaric Acids; Fluoresceins; Fluorescent Dyes; Glucose; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Lactic Acid; Membrane Transport Proteins; Mice; Monocarboxylic Acid Transporters; Potassium; Proton-Translocating ATPases; Protons; Pyruvic Acid; Rats; Sodium; Trypanosoma brucei brucei | 2000 |
Substrate profile in rat soleus muscle fibers after hindlimb unloading and fatigue.
Topics: Adenosine Triphosphate; Animals; Glycogen; Hindlimb Suspension; Lactic Acid; Male; Muscle Fatigue; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Oxidation-Reduction; Palmitates; Phosphocreatine; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2000 |
Effect of induced metabolic alkalosis on human skeletal muscle metabolism during exercise.
Topics: Adenine Nucleotides; Adult; Alkalosis; Biopsy; Exercise; Femoral Vein; Glucose; Glycogen; Humans; Hydrogen-Ion Concentration; Lactic Acid; Leg; Male; Muscle, Skeletal; Oxygen Consumption; Phosphorylases; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Radial Artery; Sodium Bicarbonate | 2000 |
Evolution of lactate/pyruvate and arterial ketone body ratios in the early course of catecholamine-treated septic shock.
Topics: Acidosis, Lactic; Adult; Aged; Aged, 80 and over; Case-Control Studies; Catecholamines; Female; Hemodynamics; Humans; Ketone Bodies; Lactic Acid; Male; Middle Aged; Prospective Studies; Pyruvic Acid; Shock, Cardiogenic; Shock, Septic; Vasoconstrictor Agents | 2000 |
Redox pairs, tissue hypoxia, organ dysfunction, and mortality.
Topics: Humans; Hypoxia; Ketone Bodies; Lactic Acid; Multiple Organ Failure; Oxidation-Reduction; Predictive Value of Tests; Pyruvic Acid; Resuscitation; Shock, Septic; United States | 2000 |
Peripheral plasma amino acid abnormalities in rehabilitation patients with severe brain injury.
Topics: Adolescent; Adult; Aged; Amino Acids; Biomarkers; Brain Injuries; Carnitine; Disability Evaluation; Female; Glycerol; Humans; Ketone Bodies; Lactic Acid; Male; Middle Aged; Nutritional Status; Pyruvic Acid; Spectrophotometry; Trauma Severity Indices | 2000 |
The effects of varying dietary fat on performance and metabolism in trained male and female runners.
Topics: Adult; Blood Glucose; Body Composition; Diet; Dietary Fats; Energy Intake; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Lactic Acid; Male; Oxygen Consumption; Physical Endurance; Pyruvic Acid; Running; Triglycerides | 2000 |
Thyroid hormone and dehydroepiandrosterone permit gluconeogenic hormone responses in hepatocytes.
Topics: Aminooxyacetic Acid; Animals; Calcium; Cyclic AMP; Dehydroepiandrosterone; Glucagon; Gluconeogenesis; Glucose; Glycerol; Glycerol-3-Phosphate Dehydrogenase (NAD+); Glycerolphosphate Dehydrogenase; Glycerophosphates; Hypothyroidism; Lactic Acid; Liver; Male; Mitochondria, Liver; Norepinephrine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thyroidectomy; Transaminases; Triiodothyronine; Vasopressins; Xylitol | 2000 |
[Dynamics of oxyhemoglobin, lactate, and pyruvate in plasma in connection with the woman menstrual cycle].
Topics: Adult; Female; Humans; Lactic Acid; Menstrual Cycle; Oxyhemoglobins; Pyruvic Acid | 1999 |
Free [ADP] and aerobic muscle work follow at least second order kinetics in rat gastrocnemius in vivo.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aerobiosis; Animals; Electric Stimulation; Energy Metabolism; Glycogen; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle, Skeletal; Phosphocreatine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2000 |
Cerebral metabolism of lactate in vivo: evidence for neuronal pyruvate carboxylation.
Topics: Animals; Blood Glucose; Brain; Carbon; Carbon Isotopes; Carbon Radioisotopes; Cell Communication; Cytosol; Eating; Fasting; Female; Fumarates; Glucose; Lactic Acid; Magnetic Resonance Spectroscopy; Malate Dehydrogenase; Malates; Mice; Mice, Inbred Strains; Mitochondria; Neuroglia; Neurons; Pyruvic Acid; Synaptosomes | 2000 |
Regulation of glycogen phosphorylase and PDH during exercise in human skeletal muscle during hypoxia.
Topics: Adenosine Triphosphate; Adult; Carnitine; Coenzyme A; Energy Metabolism; Exercise; Glycogen; Glycolysis; Heart; Humans; Hypoxia; Lactic Acid; Male; Muscle, Skeletal; Phosphates; Phosphorylases; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Respiration | 2000 |
Organic acids and volatile flavor components evolved during refrigerated storage of kefir.
Topics: Acetaldehyde; Acetoin; Animals; Carboxylic Acids; Cattle; Chromatography, Gas; Chromatography, High Pressure Liquid; Citric Acid; Ethanol; Food Preservation; Hydrogen-Ion Concentration; Lactic Acid; Milk; Pyruvic Acid; Refrigeration | 2000 |
Monitoring of extracellular pyruvate, lactate, and ascorbic acid during cerebral ischemia: a microdialysis study in awake gerbils.
Topics: Animals; Ascorbic Acid; Brain Ischemia; Gerbillinae; Lactic Acid; Microdialysis; Pyruvic Acid | 2000 |
[Regulation of distractional osteogenesis: biochemical aspects].
Topics: Animals; Animals, Newborn; Bone and Bones; Bone Density; Bone Regeneration; Cell Division; Dogs; L-Lactate Dehydrogenase; Lactic Acid; Pyruvic Acid | 2000 |
Energy metabolism in preimplantation bovine embryos derived in vitro or in vivo.
Topics: Animals; Blastocyst; Carbon Dioxide; Cattle; Culture Media; Embryonic and Fetal Development; Energy Metabolism; Female; Fertilization in Vitro; Glucose; Lactic Acid; Oocytes; Pregnancy; Pyruvic Acid | 2000 |
Effect of lactate dehydrogenase activity and isoenzyme localization in bovine oocytes and utilization of oxidative substrates on in vitro maturation.
Topics: Animals; Cattle; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Mice; Oocytes; Oxidation-Reduction; Pyruvic Acid | 1999 |
Difference in mechanism between glyceraldehyde- and glucose-induced insulin secretion from isolated rat pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diazoxide; Female; Glucose; Glyceraldehyde; In Vitro Techniques; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Lactic Acid; Nitrendipine; Pyruvic Acid; Rats; Rats, Wistar; Triose-Phosphate Isomerase | 2000 |
Relationship between motility and oxygen consumption of sperm from the cauda epididymides of the rat.
Topics: Acetates; Animals; Bucladesine; Deoxyglucose; Epididymis; Glucose; Kinetics; Lactic Acid; Male; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar; Sperm Motility; Spermatozoa | 1999 |
In vitro maturation and in vitro fertilization of bovine oocytes cultured in a chemically defined, protein-free medium: effects of carbohydrates and amino acids.
Topics: Amino Acids; Animals; Blastocyst; Carbohydrates; Cattle; Cell Nucleus; Cells, Cultured; Culture Media; Female; Fertilization in Vitro; Glucose; Lactic Acid; Male; Oocytes; Pyruvic Acid; Sperm-Ovum Interactions | 1999 |
Insulin increases NO-stimulated guanylate cyclase activity in cultured VSMC while raising redox potential.
Topics: Aerobiosis; Animals; Cells, Cultured; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Glycolysis; Guanylate Cyclase; Immunoblotting; Insulin; Lactic Acid; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Oxidation-Reduction; Penicillamine; Pyruvic Acid; S-Nitroso-N-Acetylpenicillamine | 2000 |
Effects of diet forage:concentrate ratio and metabolizable energy intake on isolated rumen epithelial cell metabolism in vitro.
Topics: Animal Feed; Animals; Carbon Dioxide; Cells, Cultured; Energy Intake; Energy Metabolism; Epithelial Cells; Female; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Rumen; Sheep | 2000 |
Acute oxygen supplementation restores markers of hepatocyte energy status and hypoxia in cirrhotic rats.
Topics: Animals; Biomarkers; Blood Gas Analysis; Carbon Tetrachloride Poisoning; Energy Metabolism; Hypoxia; Lactic Acid; Liver; Liver Cirrhosis, Experimental; Magnetic Resonance Spectroscopy; Male; Oxygen; Perchlorates; Phosphorylation; Pyruvic Acid; Rats; Rats, Wistar | 2000 |
Sodium monochloroacetate causes cytotoxic effects, an increased lactate and pyruvate level and induces ultra structural and cytoskeletal alterations in cultured kidney and liver epithelial cells.
Topics: Acetates; Animals; Cell Line; Cell Survival; Cytoskeleton; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Kidney Tubules, Proximal; Lactic Acid; Liver; Opossums; Pyruvic Acid | 2000 |
Glucoregulatory responses to intense exercise performed in the postprandial state.
Topics: Adolescent; Adult; Blood Glucose; Epinephrine; Exercise; Food; Glucagon; Glucose; Homeostasis; Humans; Insulin; Intestinal Absorption; Kinetics; Lactic Acid; Liver; Male; Norepinephrine; Oxygen Consumption; Pyruvic Acid | 2000 |
Citrate release by perfused rat hearts: a window on mitochondrial cataplerosis.
Topics: Acetyl Coenzyme A; Animals; Caprylates; Citric Acid; Energy Metabolism; Gas Chromatography-Mass Spectrometry; Glucose; In Vitro Techniques; Indicator Dilution Techniques; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria, Heart; Myocardium; Oxaloacetic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2000 |
Microdialysis of the spinal cord during thoracic aortic cross-clamping in a porcine model.
Topics: Animals; Aorta, Thoracic; Disease Models, Animal; Glucose; Glutamic Acid; Lactic Acid; Microdialysis; Monitoring, Intraoperative; Pilot Projects; Pyruvic Acid; Spinal Cord; Spinal Cord Diseases; Surgical Instruments; Swine | 2000 |
An endogenous monocarboxylate transport in Xenopus laevis oocytes.
Topics: 1-Methyl-3-isobutylxanthine; 4-Chloromercuribenzenesulfonate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cations; Chlorine; Coumaric Acids; Female; Hydrogen-Ion Concentration; Lactic Acid; Oocytes; Pyruvic Acid; Radioisotopes; Sodium; Tetraethylammonium; Xenopus laevis | 2000 |
Microdialysis-based long-term measurements of energy-related metabolites in the rat brain following a fluid percussion trauma.
Topics: Animals; Brain Chemistry; Brain Injuries; Cerebral Cortex; Energy Metabolism; Extracellular Space; Glucose; Lactic Acid; Microdialysis; Percussion; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Hyperammonemia induced by administration of glucose and insulin after hepatopancreatectomy in rats.
Topics: Alanine; Ammonia; Animals; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hepatectomy; Insulin; Lactic Acid; Male; Pancreatectomy; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Glutamic acid decarboxylase-expressing astrocytes exhibit enhanced energetic metabolism and increase PC12 cell survival under glucose deprivation.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Cell Line, Transformed; Cell Survival; Culture Media, Conditioned; Energy Metabolism; gamma-Aminobutyric Acid; Gene Expression; Glucose; Glutamate Decarboxylase; Glycogen; Isoenzymes; Lactic Acid; PC12 Cells; Pyruvic Acid; Rats; Transfection | 2000 |
Effects of naloxone on lactate, pyruvate metabolism and antioxidant enzyme activity in rat cerebral ischemia/reperfusion.
Topics: Animals; Antioxidants; Brain; Catalase; Energy Metabolism; Free Radicals; Glutathione Peroxidase; Ischemic Attack, Transient; Lactic Acid; Male; Microdialysis; Naloxone; Narcotic Antagonists; Opioid Peptides; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke; Superoxide Dismutase | 2000 |
Oxygen-transfer strategy and its regulation effects in serine alkaline protease production by Bacillus licheniformis.
Topics: Acetic Acid; Air; Amino Acids; Bacillus; Biomass; Bioreactors; Citric Acid; Citric Acid Cycle; Culture Media; Fermentation; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Oxygen; Pyruvic Acid; Serine Endopeptidases | 2000 |
Transport of protons and lactate in cultured human fetal retinal pigment epithelial cells.
Topics: Acids; Cell Size; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Fluoresceins; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ion Transport; Lactic Acid; Models, Biological; Osmolar Concentration; Pigment Epithelium of Eye; Pyruvic Acid; Sodium-Hydrogen Exchangers; Water | 2000 |
Outcome of thiamine treatment in a child with Leigh disease due to thiamine-responsive pyruvate dehydrogenase deficiency.
Topics: Child; Diagnosis, Differential; Dose-Response Relationship, Drug; Fibroblasts; Follow-Up Studies; Humans; Lactic Acid; Leigh Disease; Male; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid; Remission Induction; Thiamine | 2000 |
Effect of positive end-expiratory pressure on splanchnic perfusion in acute lung injury.
Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Female; Hemodynamics; Humans; Indocyanine Green; Intensive Care Units; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Positive-Pressure Respiration; Prospective Studies; Pyruvic Acid; Regional Blood Flow; Respiratory Distress Syndrome; Splanchnic Circulation; Statistics, Nonparametric | 2000 |
Continuous assessment of local metabolism by microdialysis in critical limb ischaemia.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Blood Pressure; Feasibility Studies; Femoral Artery; Glucose; Humans; Ischemia; Lactic Acid; Laser-Doppler Flowmetry; Leg; Microdialysis; Monitoring, Physiologic; Posture; Pyruvic Acid | 2000 |
Differences in metabolic and hormonal milieu in diabetic- and alcohol-induced ketoacidosis.
Topics: Adult; Alcoholism; Blood Glucose; Diabetic Ketoacidosis; Diagnosis, Differential; Epinephrine; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Insulin; Ketone Bodies; Ketosis; Lactic Acid; Male; Middle Aged; Pyruvic Acid; Time Factors | 2000 |
Clinical cerebral microdialysis: a methodological study.
Topics: Adult; Blood Glucose; Brain Chemistry; Brain Injuries; Catheters, Indwelling; Chromatography, High Pressure Liquid; Critical Care; Extracellular Space; Frontal Lobe; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Microdialysis; Monitoring, Physiologic; Online Systems; Pyruvic Acid; Subarachnoid Hemorrhage | 2000 |
The pathophysiologic and prognostic significance of acidosis in severe adult malaria.
Topics: Acidosis; Adolescent; Adult; Aged; Cohort Studies; Female; Hepatic Veins; Humans; Lactic Acid; Malaria, Falciparum; Male; Middle Aged; Multivariate Analysis; Prognosis; Pyruvic Acid; ROC Curve; Severity of Illness Index | 2000 |
Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions.
Topics: Acidosis, Lactic; APACHE; Biomarkers; Critical Care; Emergencies; Female; Finland; Glasgow Coma Scale; Humans; Hypoxia; Lactic Acid; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Prospective Studies; Pyruvic Acid; Risk Factors; Shock; Time Factors | 2000 |
Effects of high myoplasmic L-lactate concentration on E-C coupling in mammalian skeletal muscle.
Topics: Animals; Calcium; Diffusion; Electrophysiology; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Magnesium; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Pyruvic Acid; Rats; Rats, Wistar; Sarcoplasmic Reticulum | 2000 |
Osmolar gap metabolic acidosis in a 60-year-old man treated for hypoxemic respiratory failure.
Topics: Acidosis, Lactic; Drug Combinations; Humans; Hypnotics and Sedatives; Hypoxia; Infusions, Intravenous; Lactic Acid; Lorazepam; Male; Middle Aged; Osmolar Concentration; Oxygen Inhalation Therapy; Positive-Pressure Respiration; Propylene Glycol; Pyruvic Acid; Respiratory Insufficiency; Solvents | 2000 |
In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum.
Topics: Amino Acids; Ammonia; Biomass; Bioreactors; Carbon; Carbon Isotopes; Citric Acid Cycle; Corynebacterium; Glucose; Glycolysis; Glyoxylates; Lactic Acid; Magnetic Resonance Spectroscopy; Models, Biological; Oxaloacetates; Phosphoenolpyruvate; Pyruvic Acid | 2000 |
Rapid extracellular acidification induced by glucose metabolism in non-proliferating cells of Serratia marcescens.
Topics: Acetic Acid; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Citric Acid; Culture Media, Conditioned; Energy Metabolism; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Prodigiosin; Pyruvic Acid; Serratia marcescens; Sugar Alcohols | 2000 |
Metabolic effects induced by epinephrine in Rana balcanica erythrocytes under normoxic and hypoxic conditions.
Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Colforsin; Cyclic AMP; Epinephrine; Erythrocytes; Glucose; Hypoxia; Lactic Acid; Ouabain; Oxygen; Perchlorates; Phosphofructokinase-1; Prazosin; Propranolol; Pyruvic Acid; Ranidae; Sodium-Potassium-Exchanging ATPase; Time Factors; Yohimbine | 2000 |
Age-dependent changes in glycosaminoglycan content in the skin of fasted rats. A possible mechanism.
Topics: Aging; Animals; Blood Glucose; Fasting; Glycosaminoglycans; Lactic Acid; Male; NAD; Pyruvic Acid; Rats; Rats, Wistar; Skin; Uronic Acids | 2000 |
Pyruvate protects against 3-nitropropionic acid neurotoxicity in corticostriatal slice cultures.
Topics: Adenosine Triphosphate; Animals; Culture Techniques; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Lactic Acid; Malates; Neurotoxins; Nitro Compounds; Oxaloacetic Acid; Propidium; Propionates; Pyruvic Acid; Rats; Visual Cortex | 2000 |
Intracerebral microdialysis in clinical practice: baseline values for chemical markers during wakefulness, anesthesia, and neurosurgery.
Topics: Adult; Amino Acids; Anesthesia, General; Blood Glucose; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Glycerol; Humans; Lactic Acid; Male; Meningeal Neoplasms; Meningioma; Microdialysis; Middle Aged; Monitoring, Intraoperative; Neuroma, Acoustic; Pyruvic Acid; Reference Values; Urea; Wakefulness | 2000 |
Acidotic pH augments glucagon secretion and gluconeogenesis in the isolated perfused rat pancreas and liver.
Topics: Acidosis; Animals; Glucagon; Gluconeogenesis; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Liver; Male; Pancreas; Perfusion; Pyruvic Acid; Rats; Rats, Wistar | 2000 |
In vivo study of tumor metabolism: an application of new multi-probe microdialysis system in the striatum of freely moving rats grafted with C6 cells.
Topics: Animals; Brain Neoplasms; Corpus Striatum; Glioma; Glucose; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2000 |
Dental plaque mass and acid production activity of the microbiota on teeth.
Topics: Acetic Acid; Adolescent; Anions; Biofilms; Dental Plaque; Dental Plaque Index; Ecosystem; Female; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Male; Propionates; Pyruvic Acid; Statistics, Nonparametric | 2000 |
Partitioning of pyruvate between oxidation and anaplerosis in swine hearts.
Topics: 3-Hydroxybutyric Acid; Animals; Caprylates; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Coronary Vessels; Fatty Acids, Nonesterified; Female; Glucose; Infusions, Intra-Arterial; Lactic Acid; Male; Myocardium; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Swine; Tissue Distribution | 2000 |
Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state.
Topics: Animals; Antioxidants; Coumaric Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hydralazine; In Vitro Techniques; Lactic Acid; Mitochondria, Heart; Multienzyme Complexes; Myocardial Ischemia; Myocardium; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Pyruvic Acid; Rabbits; Reactive Oxygen Species; Xanthine Oxidase | 2000 |
Exercise-induced lactate increase in relation to muscle substrates in patients with chronic obstructive pulmonary disease.
Topics: Aged; Exercise Tolerance; Female; Glucose; Glutamic Acid; Glycogen; Humans; Lactic Acid; Leg; Lung Diseases, Obstructive; Male; Middle Aged; Muscle, Skeletal; Oxygen Consumption; Physical Exertion; Pulmonary Diffusing Capacity; Pulmonary Emphysema; Pyruvic Acid; Respiratory Mechanics | 2000 |
Serial diffusion-weighted imaging in MELAS.
Topics: Adult; Atrophy; Brain; DNA, Mitochondrial; Echo-Planar Imaging; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; MELAS Syndrome; Middle Aged; Muscle, Skeletal; Pyruvic Acid; Succinate Dehydrogenase | 2000 |
Transient improvement of pyruvate metabolism after coenzyme Q therapy in Kearns-Sayre syndrome: MRS study.
Topics: Adolescent; Brain; Female; Humans; Kearns-Sayre Syndrome; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Treatment Outcome; Ubiquinone | 2000 |
Anaerobic glycolysis is crucial for the maintenance of neural activity in guinea pig hippocampal slices.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Brain Ischemia; Energy Metabolism; Fructose; Glucose; Glycolysis; Guinea Pigs; Hippocampus; Lactic Acid; Mannose; Neurons; Organ Culture Techniques; Phosphocreatine; Pyruvic Acid | 2000 |
Importance of lactate dehydrogenase for the regulation of glycolytic flux and insulin secretion in insulin-producing cells.
Topics: Base Sequence; DNA Primers; Glucose; Glycolysis; Insulin; Insulin Secretion; Islets of Langerhans; L-Lactate Dehydrogenase; Lactic Acid; Pyruvic Acid | 2000 |
Glycolytic enzyme activity in hypotonically treated boar spermatozoa.
Topics: Adenosine Diphosphate; Animals; Buffers; Dihydroxyacetone Phosphate; Fructosediphosphates; Glyceraldehyde 3-Phosphate; Glyceric Acids; Glycolysis; Hypotonic Solutions; L-Lactate Dehydrogenase; Lactic Acid; Male; NAD; Phosphates; Phosphofructokinase-1; Pyruvic Acid; Spermatozoa; Swine | 1999 |
Functional relationships between capacitation-dependent cell signaling and compartmentalized metabolic pathways in murine spermatozoa.
Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cyclic AMP; Dose-Response Relationship, Drug; Glucose; Glycolysis; Hexokinase; Immunoblotting; Kinetics; Lactic Acid; Male; Mice; Phosphorylation; Protein Isoforms; Pyruvic Acid; Signal Transduction; Spectrophotometry; Sperm Capacitation; Spermatozoa; Time Factors; Tyrosine | 2001 |
Hepatic O2 exchange and liver energy metabolism in hyperdynamic porcine endotoxemia: effects of iloprost.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxemia; Energy Metabolism; Escherichia coli; Escherichia coli Infections; Female; Fluid Therapy; Hemodynamics; Hemoglobins; Iloprost; Lactic Acid; Lipopolysaccharides; Liver; Male; Microcirculation; Oxygen Consumption; Prospective Studies; Pyruvic Acid; Random Allocation; Resuscitation; Swine; Time Factors; Vasodilator Agents | 2000 |
Low-dose IGF-I has no selective advantage over insulin in regulating glucose metabolism in hyperglycemic depancreatized dogs.
Topics: 3-Hydroxybutyric Acid; Alanine; Analysis of Variance; Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dogs; Drug Administration Schedule; Fatty Acids, Nonesterified; Glucose Clamp Technique; Glycerol; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Male; Pancreatectomy; Pyruvic Acid | 2001 |
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport; Brain Ischemia; Cerebral Cortex; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Energy Metabolism; Ethanolamines; gamma-Aminobutyric Acid; Glucose; Glutamine; Lactic Acid; Male; Pyruvic Acid; Quercetin; Rats; Rats, Sprague-Dawley | 2001 |
Substrate utilization in porcine embryos cultured in NCSU23 and G1.2/G2.2 sequential culture media.
Topics: Animals; Blastocyst; Cleavage Stage, Ovum; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fertilization in Vitro; Glucose; Lactic Acid; Male; Morula; Pyruvic Acid; Random Allocation; Swine | 2001 |
Energy substrate requirement for in vitro maturation of oocytes from unstimulated adult rhesus monkeys.
Topics: Animals; Cells, Cultured; Culture Media; Embryonic and Fetal Development; Female; Fertilization in Vitro; Glucose; Humans; Lactic Acid; Macaca mulatta; Oocytes; Pyruvic Acid; Random Allocation | 2001 |
[5-3H]glucose overestimates glycolytic flux in isolated working rat heart: role of the pentose phosphate pathway.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; False Positive Reactions; Glucose; Glycogen; Glycolysis; Lactic Acid; Male; Myocardial Contraction; Myocardium; Pentose Phosphate Pathway; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sugar Phosphates; Transaldolase; Tritium | 2001 |
Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs.
Topics: Animals; Basilar Artery; Caspase Inhibitors; Caspases; Cerebrospinal Fluid; Disease Models, Animal; Dogs; Enzyme Inhibitors; Female; Glucose; Glutamic Acid; Lactic Acid; Male; Mitogen-Activated Protein Kinases; Pyruvic Acid; Subarachnoid Hemorrhage; Time Factors; Vasospasm, Intracranial | 2001 |
Intramitochondrial pyruvate attenuates hydrogen peroxide-induced apoptosis in bovine pulmonary artery endothelium.
Topics: Animals; Annexin A5; Apoptosis; Bisbenzimidazole; Cattle; Cell Nucleus; Cell Survival; Cells, Cultured; Coumaric Acids; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Fluorescent Dyes; Glucose; Hydrogen Peroxide; In Situ Nick-End Labeling; Lactic Acid; Microscopy, Fluorescence; Mitochondria; Oxidation-Reduction; Oxidative Stress; Propidium; Pulmonary Artery; Pyruvic Acid; Time Factors | 2001 |
Inhibitory effect of sorbitol on sugar metabolism of Streptococcus mutans in vitro and on acid production in dental plaque in vivo.
Topics: Acetic Acid; Acetyltransferases; Adult; Aged; Dental Plaque; Female; Formates; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Humans; Hydrogen-Ion Concentration; Ion-Selective Electrodes; Lactic Acid; Middle Aged; NAD; Oxygen; Pyruvic Acid; Sorbitol; Streptococcus mutans; Sucrose | 2001 |
Beneficial effects of low-dose prostacyclin on cat intestinal perfusion during endotoxemia as evaluated with microdialysis and oxygen transport variables.
Topics: Animals; Antihypertensive Agents; Blood Gas Analysis; Cats; Constriction, Pathologic; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxemia; Energy Metabolism; Epoprostenol; Hemodynamics; Hydrogen-Ion Concentration; Infusions, Intravenous; Intestinal Mucosa; Lactic Acid; Microcirculation; Microdialysis; Oxygen Consumption; Pyruvic Acid; Random Allocation; Single-Blind Method; Vascular Resistance | 2001 |
Chemo-enzymatic D-enantiomerization of DL-lactate.
Topics: Borohydrides; Lactic Acid; Mixed Function Oxygenases; Molecular Conformation; Oxidation-Reduction; Pyruvic Acid; Stereoisomerism; Time Factors | 2001 |
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Pentosephosphates; Pyruvaldehyde; Pyruvic Acid; Sugar Phosphates; Thiamine; Transketolase; Trioses | 2001 |
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
Topics: Adrenergic alpha-Antagonists; Ammonia; Animals; Antioxidants; Cell Fractionation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Glutamic Acid; Imidazoles; Imidazolidines; Ketoglutaric Acids; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Piperazines; Prazosin; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Thioctic Acid | 2001 |
[An autopsy case of neonatal lactic acidosis].
Topics: Acidosis, Lactic; Atrophy; Autopsy; Body Fluids; Brain; Cardiomegaly; Epilepsy, Generalized; Fatal Outcome; Female; Humans; Infant, Newborn; Lactic Acid; Mitochondria; Mitochondrial Myopathies; Muscle, Skeletal; Pyruvic Acid; Spasms, Infantile | 2001 |
Spatial heterogeneity of energy turnover in the heart.
Topics: Alanine; Animals; Aspartic Acid; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Coronary Circulation; Dogs; Energy Metabolism; Glutamic Acid; Ketoglutaric Acids; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; Models, Biological; Myocardium; Oxaloacetic Acid; Oxygen Consumption; Pyruvic Acid | 2001 |
Effects of cibenzoline on cardiac function and metabolism in the rat heart--lung preparation.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiac Output; Dose-Response Relationship, Drug; Heart; Heart Rate; Hemodynamics; Imidazoles; Lactic Acid; Lung; Male; Myocardium; Pyruvic Acid; Rats; Rats, Wistar; Ventricular Function, Left | 2001 |
Transport of lactate and pyruvate in the intraerythrocytic malaria parasite, Plasmodium falciparum.
Topics: Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Erythrocytes; Glycolysis; Humans; Hydrogen; Hydrogen-Ion Concentration; Ion Transport; Kinetics; Lactic Acid; Malaria, Falciparum; Monocarboxylic Acid Transporters; Phloretin; Plasmodium falciparum; Pyruvic Acid; Saponins | 2001 |
The simulated microgravity environment maintains key metabolic functions and promotes aggregation of primary porcine hepatocytes.
Topics: Amino Acids; Animals; Cell Aggregation; Cell Division; Cell Survival; Chromatography, High Pressure Liquid; Culture Media; Glucose; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Pyruvic Acid; Swine; Time Factors; Weightlessness | 2001 |
13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Compartmentation; Cell Extracts; Cells, Cultured; Culture Media; Cytosol; Energy Metabolism; Enzymes; Glucose; Glutamic Acid; Glutamine; Hydrogen; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2001 |
Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity.
Topics: Animals; Animals, Newborn; Astrocytes; Catalase; Cell Survival; Cells, Cultured; Cerebrospinal Fluid; Chlorides; Chromatography, High Pressure Liquid; Copper; Cysteine; Cytoprotection; Dose-Response Relationship, Drug; Ferric Compounds; Hydroxyl Radical; Lactic Acid; Male; Metals; Neurons; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Long-Evans | 2001 |
Rates of gluconeogenesis in perfused liver of alloxan-diabetic fed rats.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fructose; Gluconeogenesis; Glucose; Glutamine; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Uric Acid | 2000 |
Effects of hypothermic deep-anaesthesia on energy metabolism at brain and peripheral levels: a multi-probe microdialysis study in free-moving rat.
Topics: Adjuvants, Anesthesia; Animals; Brain; Energy Metabolism; Glucose; Hypothermia, Induced; Lactic Acid; Male; Microdialysis; Pentobarbital; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2001 |
Assessment of metabolism of equine morulae and blastocysts.
Topics: Animals; Blastocyst; Cell Size; Cytophotometry; Female; Glucose; Horses; Lactic Acid; Morula; Pyruvic Acid | 2001 |
Blood oxygen binding in calves with naturally occurring diarrhea.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Animals, Newborn; Carbon Dioxide; Cattle; Cattle Diseases; Chlorides; Dehydration; Diarrhea; Female; Lactic Acid; Oxygen; Oxyhemoglobins; Partial Pressure; Phosphates; Pyruvic Acid | 2001 |
Norepinephrine infusion during moderate-intensity exercise increases glucose production and uptake.
Topics: Adult; Exercise; Glucose; Humans; Lactic Acid; Male; Norepinephrine; Oxygen Consumption; Pyruvic Acid | 2001 |
Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Disease Models, Animal; Energy Metabolism; Extracorporeal Circulation; Guanine; Heart Arrest, Induced; Hypoxanthine; Inosine; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardium; Pyruvic Acid; Reperfusion Injury; Swine; Taurine | 2001 |
Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Cryoprotective Agents; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2001 |
NADH: sensor of blood flow need in brain, muscle, and other tissues.
Topics: Animals; Brain; Cytosol; Lactic Acid; Muscle Contraction; Muscles; NAD; Physical Conditioning, Animal; Pyruvic Acid; Rats; Regional Blood Flow; Seizures; Signal Transduction; Vibrissae | 2001 |
An NMR and enzyme study of the carbon metabolism of Neisseria meningitidis.
Topics: Acetate Kinase; Carbon; Citric Acid Cycle; Culture Media; Glucose; Lactic Acid; Magnetic Resonance Spectroscopy; Neisseria meningitidis; Phosphate Acetyltransferase; Pyruvic Acid | 2001 |
[Mitochondrial DNA T to G mutation 8993 in Leigh encephalopathy and organic aciduria].
Topics: DNA, Mitochondrial; Female; Humans; Infant; Ketoglutaric Acids; Lactic Acid; Leigh Disease; Magnetic Resonance Imaging; Mutation; Pyruvic Acid | 2001 |
Increased ileal-mucosal-arterial PCO2 gap is associated with impaired villus microcirculation in endotoxic pigs.
Topics: Animals; Blood Gas Analysis; Carbon Dioxide; Disease Models, Animal; Endotoxemia; Escherichia coli Infections; Female; Ileum; Intestinal Mucosa; Lactic Acid; Male; Mesenteric Arteries; Microcirculation; Microscopy, Polarization; Portal Vein; Prospective Studies; Pyruvic Acid; Spectrophotometry; Swine | 2001 |
Partial amino acid catabolism leading to the formation of alanine in Periophthalmodon schlosseri (mudskipper): a strategy that facilitates the use of amino acids as an energy source during locomotory activity on land.
Topics: Adenosine Triphosphate; Air; Alanine; Amino Acids; Animals; Citric Acid Cycle; Energy Metabolism; Glycogen; Lactic Acid; Liver; Malate Dehydrogenase; Malates; Motor Activity; Muscles; Oxidation-Reduction; Perciformes; Photoperiod; Physical Exertion; Pyruvic Acid | 2001 |
Dynamics of pyruvate metabolism in Lactococcus lactis.
Topics: Acetates; Acetyltransferases; Anaerobiosis; Biomass; Ethanol; Fermentation; Formates; Glucose; Glycolysis; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Lactococcus lactis; Models, Biological; Pyruvic Acid | 2001 |
Middle cerebral artery occlusion and reperfusion in primates monitored by microdialysis and sequential positron emission tomography.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Glutamic Acid; Hypoxanthine; Infarction, Middle Cerebral Artery; Lactic Acid; Macaca mulatta; Microdialysis; Oxygen Consumption; Pyruvic Acid; Reperfusion Injury; Tomography, Emission-Computed | 2001 |
Force reduction uncoupled from pH and H(2)PO(-)(4) in rat gastrocnemius in vivo with continuous 2-Hz stimulation.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Glycogen; Hydrogen-Ion Concentration; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Phosphates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
On-line monitoring of substrate delivery and brain metabolism in head injury.
Topics: Adolescent; Adult; Aged; Blood Glucose; Brain Injuries; Catheters, Indwelling; Energy Metabolism; Female; Frontal Lobe; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Online Systems; Prognosis; Pyruvic Acid; Survival Rate | 2000 |
Allosteric activation of pyruvate kinase via NAD+ in rat liver cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Cell Separation; Dihydroxyacetone Phosphate; Energy Metabolism; Lactic Acid; Liver; Male; NAD; Niacinamide; Phosphoenolpyruvate; Pyruvate Kinase; Pyruvic Acid; Rats; Rats, Wistar | 2001 |
Induced mitochondrial failure in the feline brain: implications for understanding acute post-traumatic metabolic events.
Topics: Animals; Brain; Brain Injuries; Carbon Dioxide; Cats; Cerebrovascular Circulation; Energy Metabolism; Extracellular Space; Glucose; Glutamic Acid; Hydrogen-Ion Concentration; Lactic Acid; Male; Microscopy, Electron; Mitochondria; Neurons; Oxygen; Perfusion; Potassium Cyanide; Pyruvic Acid | 2001 |
Comparison between hypothermia and glutamate antagonism treatments on the immediate outcome of perinatal asphyxia.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Aspartic Acid; Asphyxia Neonatorum; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Heart; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Kidney; Lactic Acid; Maternal Behavior; Microdialysis; Pyruvic Acid; Quinoxalines; Rats; Receptors, Glutamate; Survival Rate; Treatment Outcome | 2001 |
Identification of lactate. Analytical methods of pharmacopoeias with DBH in respect to environmental and economical concern, Part 4.
Topics: Bromates; Environmental Pollutants; Enzymes, Immobilized; Hydantoins; Indicators and Reagents; Lactic Acid; Mixed Function Oxygenases; Oxidation-Reduction; Pharmacopoeias as Topic; Pyruvic Acid | 2001 |
Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes.
Topics: Amino Acids; Animals; Astrocytes; Carbon Radioisotopes; Cell Compartmentation; Cells, Cultured; Cerebellum; Citric Acid; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Intracellular Fluid; Lactic Acid; Mice; Pyruvic Acid | 2001 |
Mitochondrial energy metabolism in brain-dead organ donors.
Topics: Adenosine Triphosphate; Adult; Brain Death; Case-Control Studies; Energy Metabolism; Female; Humans; Lactic Acid; Male; Middle Aged; Mitochondria, Muscle; Oxygen Consumption; Pyruvic Acid; Tissue Donors | 2000 |
[Acute effect of 7% CO2 breathing on lactate, pyruvate and ketone body metabolism in healthy subjects].
Topics: Acute Disease; Adult; Carbon Dioxide; Energy Metabolism; Female; Humans; Hypercapnia; Ketone Bodies; Lactic Acid; Male; Mitochondria; Pyruvic Acid | 2001 |
Respiratory chain deficiency in Alpers syndrome.
Topics: Atrophy; Biopsy, Needle; Cerebral Cortex; Child, Preschool; Consanguinity; Diagnosis, Differential; Diffuse Cerebral Sclerosis of Schilder; Electron Transport; Enzymes; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Ketone Bodies; Lactic Acid; Liver; Male; Pyruvic Acid; Status Epilepticus | 2001 |
Brain energy metabolism during controlled reduction of cerebral perfusion pressure in severe head injuries.
Topics: Adolescent; Adult; Aged; Biomarkers; Brain Injuries; Cerebrovascular Circulation; Child; Child, Preschool; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Hemodynamics; Humans; Infant; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid | 2001 |
Muscle metabolism during exercise in dogs after 8-week confinement.
Topics: Adenine Nucleotides; Animals; Creatine; Dogs; Glycogen; Housing, Animal; Immobilization; Lactic Acid; Male; Muscle, Skeletal; Phosphocreatine; Physical Conditioning, Animal; Pyruvic Acid | 1996 |
Is ischemia involved in the pathogenesis of murine cerebral malaria?
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Female; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Malaria, Cerebral; Mice; Mice, Inbred CBA; NAD; Osmolar Concentration; Pyruvic Acid | 2001 |
Effects of acetoacetate on in vitro development of bovine embryos in medium containing citrate and myo-inositol.
Topics: Acetoacetates; Animals; Blastocyst; Cattle; Citric Acid; Culture Media, Serum-Free; Embryonic and Fetal Development; Female; Fertilization in Vitro; Inositol; Lactic Acid; Oocytes; Pyruvic Acid; Serum Albumin, Bovine | 2001 |
Increase of interstitial glycerol reflects the degree of ischaemic brain damage: a PET and microdialysis study in a middle cerebral artery occlusion-reperfusion primate model.
Topics: Animals; Brain Damage, Chronic; Extracellular Space; Glutamic Acid; Glycerol; Infarction, Middle Cerebral Artery; Lactic Acid; Macaca mulatta; Microdialysis; Oxygen Consumption; Phospholipids; Pyruvic Acid; Reperfusion Injury; Tomography, Emission-Computed | 2001 |
Effect of conventional controlled-rate freezing and vitrification on morphology and metabolism of bovine blastocysts produced in vitro.
Topics: Animals; Blastocyst; Cattle; Cell Count; Cell Membrane Permeability; Cells, Cultured; Cryopreservation; Ethylene Glycol; Female; Fertilization in Vitro; Freezing; Glucose; Glycerol; Hot Temperature; Lactic Acid; Oxygen Consumption; Pyruvic Acid | 2001 |
Determination of lactic acid, pyruvic acid, and ketone bodies in serum and cerebrospinal fluid by HPLC.
Topics: Chromatography, High Pressure Liquid; Humans; Ketone Bodies; Lactic Acid; Pyruvic Acid; Reference Values | 2001 |
Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions.
Topics: Adult; Aged; Brain; Brain Injuries; Brain Ischemia; Energy Metabolism; Female; Glucose; Glycerol; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid | 2001 |
[Novel methods in diabetes mellitus diagnosis].
Topics: Cadaver; Coma; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucose; Humans; Hyperglycemia; Lactic Acid; Pyruvic Acid; Tears; Vitreous Body | 2001 |
Simultaneous monitoring of extracellular glucose, pyruvate, and lactate in rat testies during ischemia: a microdialysis study.
Topics: Animals; Extracellular Space; Glucose; Ischemia; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion; Testis | 2001 |
Estimation of gluconeogenesis in newborn infants.
Topics: Amino Acids; Blood Glucose; Body Water; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Female; Gluconeogenesis; Glucose; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Lactic Acid; Parenteral Nutrition; Pregnancy; Pregnancy in Diabetics; Pyruvic Acid | 2001 |
Effect of hyperbaric oxygen on striatal metabolites: a microdialysis study in awake freely moving rats after MCA occlusion.
Topics: Animals; Brain Ischemia; Corpus Striatum; Energy Metabolism; Extracellular Space; Glucose; Glutamic Acid; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Lactic Acid; Male; Microdialysis; Movement; Neurons; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Wakefulness | 2001 |
Impaired redox status and cytochrome c oxidase deficiency in patients with polymyalgia rheumatica.
Topics: Aged; Aged, 80 and over; Biopsy; Case-Control Studies; Cytochrome-c Oxidase Deficiency; Female; Humans; Lactic Acid; Male; Middle Aged; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Oxidation-Reduction; Polymyalgia Rheumatica; Prospective Studies; Pyruvic Acid; Statistics, Nonparametric; Succinate Dehydrogenase | 2001 |
Vero cells, but not oviductal cells, increase the hatching frequency and total cell count of mouse blastocysts partly by changing energy substrate concentrations in culture medium.
Topics: Animals; Blastocyst; Chlorocebus aethiops; Coculture Techniques; Culture Media, Conditioned; Embryonic and Fetal Development; Fallopian Tubes; Female; Glutamine; Humans; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Pyruvic Acid; Vero Cells | 2001 |
In vitro secretion of metabolic end-products by piscine haemoflagellates Cryptobia salmositica and C. bullocki (Kinetoplastida: Bodonidae) and the relationship of these products to the pH in the medium.
Topics: Animals; Culture Media; Culture Media, Serum-Free; Fishes; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetoplastida; Lactic Acid; Leeches; Oncorhynchus mykiss; Pyruvic Acid; Temperature | 2001 |
Flux of amino acids and energy substrates across the leg in weight-stable HIV-infected patients with acute opportunistic infections: indication of a slow protein wasting process.
Topics: Adult; AIDS-Related Opportunistic Infections; Amino Acids; Arginine; Blood Glucose; Case-Control Studies; Dose-Response Relationship, Drug; Erythrocytes; Fatty Acids; Female; Glycerol; HIV Seropositivity; HIV Wasting Syndrome; Humans; Insulin; Interleukin-6; Ketones; Lactic Acid; Leg; Lysine; Male; Middle Aged; Muscle, Skeletal; Nitrogen; Pyruvic Acid | 2001 |
Sodium pyruvate is better than sodium chloride as a resuscitation solution in a rodent model of profound hemorrhagic shock.
Topics: Animals; Blood Glucose; Cardiotonic Agents; Disease Models, Animal; Lactic Acid; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Sodium Chloride; Survival Rate | 2001 |
Neurometabolic changes during treatment with moderate hypothermia in a patient suffering from severe middle cerebral artery infarction.
Topics: Adult; Brain Ischemia; Extracellular Space; Glutamic Acid; Glycerol; Humans; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Lactic Acid; Microdialysis; Pyruvic Acid; Tomography, X-Ray Computed | 2001 |
Efficient homolactic fermentation by Kluyveromyces lactis strains defective in pyruvate utilization and transformed with the heterologous LDH gene.
Topics: Culture Media; Fermentation; Gene Deletion; Kluyveromyces; L-Lactate Dehydrogenase; Lactic Acid; Pyruvate Decarboxylase; Pyruvic Acid; Transformation, Genetic | 2001 |
Effects of glibenclamide on hydroxyl radical formation in the postischaemic reperfused heart with or without inhalation anaesthetics.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Glyburide; Glycogen; Hemodynamics; Hydroxybenzoates; Hydroxyl Radical; Isoflurane; Lactic Acid; Male; Methyl Ethers; Myocardial Reperfusion; Myocardium; Potassium Channel Blockers; Pyruvic Acid; Rats; Rats, Wistar; Sevoflurane | 2001 |
Glycolysis in neurons, not astrocytes, delays oxidative metabolism of human visual cortex during sustained checkerboard stimulation in vivo.
Topics: Animals; Astrocytes; Computer Simulation; Glycolysis; Humans; Lactic Acid; Models, Neurological; Neurons; Oxidative Phosphorylation; Oxygen; Oxygen Consumption; Pyruvic Acid; Visual Cortex | 2001 |
Enhanced pyruvate dehydrogenase activity does not affect muscle O2 uptake at onset of intense exercise in humans.
Topics: Adult; Dichloroacetic Acid; Enzyme Activation; Humans; Lactic Acid; Male; Muscle, Skeletal; Oxygen; Oxygen Consumption; Phosphocreatine; Physical Exertion; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Regional Blood Flow; Thigh | 2002 |
Alpha-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: implications for lactate as an energy substrate for neurons.
Topics: Animals; Astrocytes; Brain; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Coumaric Acids; Dose-Response Relationship, Drug; Down-Regulation; Female; Fetus; Glucose; Lactic Acid; Monosaccharide Transport Proteins; Neurons; Oxidative Phosphorylation; Pregnancy; Pyruvic Acid; Rats | 2001 |
Elucidation of the quantitative significance of pyruvate carboxylation in cultured cerebellar neurons and astrocytes.
Topics: Amino Acids; Animals; Aspartic Acid; Astrocytes; Brain; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Cerebellum; Citric Acid Cycle; Convulsants; Glucose; Lactic Acid; Mice; Neurons; Nitro Compounds; Oxidative Phosphorylation; Propionates; Pyruvic Acid | 2001 |
Discrepant outcome between myocardial energy-related metabolites and infarct size limitation during retroperfusion of the coronary sinus.
Topics: Animals; Coronary Circulation; Energy Metabolism; Guanosine; Jugular Veins; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Pyruvic Acid; Swine | 2001 |
Cerebrospinal fluid purines, pyrimidines, organic acids and amino acids in neonatal citrullinaemia.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Child; Child, Preschool; Citrullinemia; Humans; Infant; Infant, Newborn; Lactic Acid; Purines; Pyrimidines; Pyrrolidonecarboxylic Acid; Pyruvic Acid | 2000 |
Post-operative monitoring of cortical taurine in patients with subarachnoid hemorrhage: a microdialysis study.
Topics: Adult; Cerebral Cortex; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Monitoring, Physiologic; Postoperative Period; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage; Taurine | 2000 |
Juvenile sturgeon exhibit reduced physiological responses to exercise.
Topics: Ammonia; Animals; Blood; Energy Metabolism; Fishes; Glucose; Kinetics; Lactic Acid; Muscle, Skeletal; Osmolar Concentration; Oxygen Consumption; Phosphocreatine; Physical Exertion; Pyruvic Acid | 2001 |
Metabolism in pedicled and free TRAM flaps: a comparison using the microdialysis technique.
Topics: Abdominal Muscles; Adult; Aged; Female; Glucose; Glycerol; Humans; Ischemia; Lactic Acid; Mammaplasty; Mastectomy; Microdialysis; Middle Aged; Monitoring, Intraoperative; Postoperative Period; Pyruvic Acid; Regional Blood Flow; Reperfusion; Surgical Flaps | 2002 |
Microdialysis in abdominal surgery.
Topics: Abdomen; Adult; Aged; Digestive System Diseases; Glucose; Glycerol; Humans; Lactic Acid; Microdialysis; Middle Aged; Monitoring, Intraoperative; Pyruvic Acid | 2002 |
Intrinsic factors involved in the depression of neuronal activity induced by temperature increase in rat hippocampal neurons.
Topics: Adenosine; Animals; Glucose; Glyburide; Hippocampus; Lactic Acid; Male; Neurons; NG-Nitroarginine Methyl Ester; Pyruvic Acid; Rats; Rats, Wistar; Temperature; Vitamin B 12 | 2001 |
Fetal hepatic and umbilical uptakes of glucogenic substrates during a glucagon-somatostatin infusion.
Topics: Alanine; Animals; Arginine; Blood Glucose; Female; Fetal Blood; Gestational Age; Glucagon; Gluconeogenesis; Glucose; Glutamine; Lactic Acid; Liver; Ornithine; Oxygen Consumption; Placenta; Pregnancy; Pyruvic Acid; Sheep; Somatostatin; Umbilical Veins | 2002 |
Effect of extracellular pH on insulin secretion and glucose metabolism in neonatal and adult rat pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Calcium; DNA; Glucose; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Islets of Langerhans; Lactic Acid; Pyruvic Acid; Rats; Rats, Inbred Lew | 2001 |
Glucose deprivation decreases nitric oxide production via NADPH depletion in immunostimulated rat primary astrocytes.
Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Astrocytes; Biopterins; Cell Death; Cells, Cultured; Central Nervous System; Deoxyglucose; Down-Regulation; Glucose; Glutathione; Interferon-gamma; Lactic Acid; Lipopolysaccharides; NADP; Neurodegenerative Diseases; Nitric Oxide; Nitric Oxide Synthase; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2002 |
Determination of serum organic acids in puppies with naturally acquired parvoviral enteritis.
Topics: 3-Hydroxybutyric Acid; Acetates; Acid-Base Equilibrium; Acidosis; Animals; Animals, Newborn; Blood Gas Analysis; Chromatography, High Pressure Liquid; Dog Diseases; Dogs; Electrolytes; Enteritis; Female; Lactic Acid; Male; Parvoviridae Infections; Parvovirus, Canine; Pyruvic Acid | 2002 |
Effect of AICAR treatment on glycogen metabolism in skeletal muscle.
Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Enzyme Activation; Glucose; Glycogen; Glycogen Phosphorylase; Glycogen Synthase; Isoenzymes; Kinetics; Lactic Acid; Male; Multienzyme Complexes; Muscle, Skeletal; Phosphorylation; Protein Serine-Threonine Kinases; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ribonucleotides | 2002 |
Submaximal exercise in healthy volunteers: the relationship between gastric mucosal and systemic energy status.
Topics: Adult; Blood Pressure; Carbon Dioxide; Energy Metabolism; Exercise; Exercise Test; Gastric Mucosa; Heart Rate; Humans; Lactic Acid; Male; Pyruvic Acid; Splanchnic Circulation | 2002 |
Development of a CE method to analyze organic acids in dairy products: application to study the metabolism of heat-shocked spores.
Topics: Acetic Acid; Animals; Butyric Acid; Carboxylic Acids; Citric Acid; Dairy Products; Electrophoresis, Capillary; Formates; Hot Temperature; Hydrogen-Ion Concentration; Lactic Acid; Orotic Acid; Oxalic Acid; Propionates; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity; Spores, Bacterial; Succinic Acid; Uric Acid | 2002 |
Reversal of hypercapnia induces KATP channel and NO-independent constriction of basilar artery in rabbits with acute metabolic alkalosis.
Topics: Adrenergic alpha-Agonists; Alkalosis; Animals; ATP-Binding Cassette Transporters; Basilar Artery; Blood Pressure; Carbon Dioxide; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hydrogen-Ion Concentration; Hypercapnia; KATP Channels; Ketamine; Lactic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxygen; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyruvic Acid; Rabbits; Vasoconstriction; Xylazine | 2000 |
Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1'S,2'R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy.
Topics: Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Animals; Carbon Isotopes; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Guinea Pigs; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Oocytes; Pyruvate Carboxylase; Pyruvic Acid; Xenopus laevis | 2002 |
Effect of diet supplementation with l-carnitine on hepatic catabolism of l-alanine in rats.
Topics: Alanine; Animals; Carnitine; Dietary Supplements; Glucose; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2002 |
Mitochondrial cardiomyopathy--case report.
Topics: Adult; Cardiomyopathy, Hypertrophic; Energy Metabolism; Female; Humans; Infant; Lactic Acid; Male; Mitochondria, Heart; Mitochondrial Myopathies; Pyruvic Acid | 2002 |
Accelerated rates of glycolysis in the hypertrophied heart: are they a methodological artifact?
Topics: Animals; Artifacts; Blood Pressure; Glucose; Glucosephosphate Dehydrogenase; Glycolysis; Heart Rate; Hypertrophy, Left Ventricular; Lactic Acid; Male; Myocardium; Organ Size; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Transaldolase; Tritium | 2002 |
Glycogen levels and glycogen catabolism in livers from arthritic rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arthritis, Experimental; Blood Glucose; Cyclic AMP; Glucagon; Glycogen; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar | 2002 |
Insulin increases NADH/NAD+ redox state, which stimulates guanylate cyclase in vascular smooth muscle.
Topics: Animals; Cells, Cultured; Cyclic GMP; Dogs; Guanylate Cyclase; Indazoles; Insulin; Isocitrates; Lactic Acid; Muscle, Smooth, Vascular; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxaloacetic Acid; Oxidation-Reduction; Pyruvic Acid; Stimulation, Chemical | 2002 |
Increased synthesis of nitric oxide in rat brain cortex due to halogenated volatile anesthetics confirmed by EPR spectroscopy.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Brain Chemistry; Calibration; Cerebral Cortex; Electron Spin Resonance Spectroscopy; Energy Metabolism; Enzyme Inhibitors; Halothane; Isoflurane; Lactic Acid; Male; Methyl Ethers; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pyruvic Acid; Rats; Rats, Wistar; Sevoflurane; Spin Trapping; Stimulation, Chemical | 2002 |
Effects of indomethacin on energy metabolism in rat jejunal tissue in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Culture Techniques; Energy Metabolism; Humans; Indomethacin; Jejunum; Lactic Acid; Male; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2002 |
A theoretical approach to the link between oxidoreductions and pyrite formation in the early stage of evolution.
Topics: Biological Evolution; Iron; Lactic Acid; Lactoylglutathione Lyase; Origin of Life; Oxidation-Reduction; Pyruvic Acid; Sulfides; Thermodynamics | 2002 |
Metabolic changes in the liver graft monitored continuously with microdialysis during liver transplantation in a pig model.
Topics: Animals; Female; Glucose; Glycerol; Intraoperative Period; Lactic Acid; Liver; Liver Transplantation; Microdialysis; Monitoring, Physiologic; Pyruvic Acid; Swine | 2002 |
Analyte flux through chronically implanted subcutaneous polyamide membranes differs in humans and rats.
Topics: Adult; Animals; Biocompatible Materials; Blood Glucose; Glucose; Glycerol; Humans; Lactic Acid; Male; Membranes, Artificial; Microdialysis; Microscopy, Electron; Nylons; Prostheses and Implants; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Species Specificity; Time Factors; Urea | 2002 |
Adverse cerebral events detected after subarachnoid hemorrhage using brain oxygen and microdialysis probes.
Topics: Brain; Brain Ischemia; Carbon Dioxide; Cerebral Angiography; Cerebral Infarction; Disabled Persons; Glutamic Acid; Hematoma; Humans; Hydrogen-Ion Concentration; Lactic Acid; Microdialysis; Monitoring, Physiologic; Oxygen; Partial Pressure; Prospective Studies; Pyruvic Acid; Recurrence; Subarachnoid Hemorrhage; Treatment Outcome | 2002 |
The oxygen debt during routine cardiac surgery: illusion or reality?
Topics: Aged; Biological Availability; Coronary Artery Bypass; Female; Humans; Hypoxia; Lactic Acid; Male; Middle Aged; Oxygen; Oxygen Consumption; Pyruvic Acid; Time Factors; Vascular Resistance | 2002 |
Monitoring of porcine myocardial ischemia and reperfusion by intravasal microdialysis.
Topics: Animals; Biomarkers; Blood Glucose; Disease Models, Animal; Female; Glutamic Acid; Glycerol; Hemodynamics; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Probability; Pyruvic Acid; Random Allocation; Reference Values; Sensitivity and Specificity; Swine | 2002 |
Nicotine increases hepatic oxygen uptake in the isolated perfused rat liver by inhibiting glycolysis.
Topics: Animals; Calcium; Cell Separation; Cotinine; Electron Transport; Glucagon; Glucose; Glycolysis; Hepatocytes; In Vitro Techniques; Intracellular Fluid; Ketone Bodies; Lactic Acid; Liver; Male; Mitochondrial ADP, ATP Translocases; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tubocurarine; Up-Regulation | 2002 |
Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Bacterial Infections; Blood Pressure; Brain; Cerebral Palsy; Encephalitis; Endotoxins; Energy Metabolism; Extracellular Space; Female; Hypoxia-Ischemia, Brain; Interleukin-10; Lactic Acid; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvic Acid; Swine; Tumor Necrosis Factor-alpha | 2002 |
Amino acid kinetics during the anhepatic phase of liver transplantation.
Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid | 2002 |
A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.
Topics: Adenosine Triphosphate; Alanine; Carbon Isotopes; Cell Line; Citric Acid Cycle; Clone Cells; Glucose; Glutamic Acid; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Oligomycins; Oxidation-Reduction; Oxidative Phosphorylation; Pyruvic Acid | 2002 |
No evidence of an intracellular lactate shuttle in rat skeletal muscle.
Topics: Animals; Cytosol; Electrophoresis, Agar Gel; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Mitochondria, Muscle; Muscle, Skeletal; Oxidation-Reduction; Polarography; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2002 |
Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: a combined microdialysis and triple oxygen positron emission tomography study.
Topics: Adolescent; Adult; Brain; Brain Chemistry; Brain Injuries; Cerebrovascular Circulation; Female; Glucose; Glutamic Acid; Humans; Hyperventilation; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Tomography, Emission-Computed | 2002 |
Capacitation and acrosomal exocytosis are enhanced by incubation of stallion spermatozoa in a commercial semen extender.
Topics: Acrosome; Albumins; Animals; Calcium; Cell Survival; Cold Temperature; Horses; Isotonic Solutions; Lactic Acid; Male; Milk; Pyruvic Acid; Semen Preservation; Solutions; Sperm Capacitation; Sperm Motility; Spermatozoa | 2002 |
Cardiac carbohydrate metabolism in Zucker diabetic fatty rats.
Topics: Animals; Carbohydrate Metabolism; Carbon Isotopes; Diabetes Mellitus, Type 2; Fatty Acids; Glucose; Glycolysis; Ketone Oxidoreductases; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Obesity; Perfusion; Pyruvic Acid; Rats; Rats, Zucker; Systole | 2002 |
Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Energy Metabolism; Gerbillinae; Glucose; Glutamic Acid; Lactic Acid; Magnesium Sulfate; Microdialysis; Pyruvic Acid; Reperfusion Injury | 2002 |
Hepatic gluconeogenic capacity from various precursors in young versus old rats.
Topics: Aging; Alanine; Animals; Body Weight; Cell Separation; Cell Survival; Dihydroxyacetone; Fasting; Fructose; Gluconeogenesis; Glucose; Glutamine; Glycerol; Glycogen; Hepatocytes; Lactic Acid; Liver; Male; Oxaloacetates; Pyruvic Acid; Rats; Rats, Inbred F344 | 2002 |
Effect of octreotide acetate on the plasma concentration and urinary excretion of uridine and purine bases.
Topics: Adult; Blood Glucose; Chlorides; Creatinine; Cyclic AMP; Glucagon; Hormones; Humans; Insulin; Lactic Acid; Middle Aged; Octreotide; Purines; Pyruvic Acid; Sodium; Uridine | 2002 |
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Female; Glucose; Hypoxanthine; Hypoxia; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Pregnancy; Protons; Pyruvic Acid; Sheep; Succinic Acid; Valine | 2002 |
Reduction of Alamar Blue, a novel redox indicator, is dependent on both the glycolytic and oxidative metabolism of glucose in rat cultured neurons.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Coloring Agents; Enzyme Inhibitors; Fetus; Glucose; Glycolysis; Indicators and Reagents; Iodoacetates; Lactic Acid; Neurons; Nitro Compounds; Oxazines; Oxidation-Reduction; Propionates; Pyruvic Acid; Rats; Xanthenes | 2002 |
Changes in cerebral glycolytic activity during transport of critically ill neurotrauma patients measured with microdialysis.
Topics: Adolescent; Aged; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Critical Care; Critical Illness; Energy Metabolism; Female; Glucose; Glycolysis; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Respiration, Artificial; Transportation of Patients | 2002 |
Multiple operons connected with catabolism of aromatic compounds in Acinetobacter sp. strain ADP1 are under carbon catabolite repression.
Topics: Acinetobacter; Carbon; Glucose; Hydroxybenzoates; Kinetics; Lactic Acid; Operon; Parabens; Pyruvic Acid; Restriction Mapping; RNA, Bacterial; RNA, Ribosomal, 16S; RNA, Ribosomal, 23S; Succinic Acid; Transcription, Genetic | 2002 |
Mitochondrial disorders: a potentially under-recognized etiology of infantile spasms.
Topics: Diagnosis, Differential; DNA, Mitochondrial; Energy Metabolism; Female; Humans; Infant; Infant, Newborn; Lactic Acid; Male; Mitochondrial Diseases; Point Mutation; Polymerase Chain Reaction; Pyruvic Acid; Retrospective Studies; Spasms, Infantile; Twins | 2002 |
Clinical cerebral microdialysis--determining the true extracellular concentration.
Topics: Biomarkers; Blood Flow Velocity; Brain; Catheters, Indwelling; Cerebrovascular Circulation; Extracellular Space; Frontal Lobe; Glucose; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Monitoring, Physiologic; Neurosurgical Procedures; Perfusion; Postoperative Care; Prognosis; Pyruvic Acid | 2002 |
Extracellular lactate/pyruvate and glutamate changes in patients during per-operative episodes of cerebral ischaemia.
Topics: Adult; Aged; Biomarkers; Brain; Brain Ischemia; Carotid Artery, Internal; Craniotomy; Glutamic Acid; Humans; Intracranial Aneurysm; Lactic Acid; Middle Aged; Monitoring, Intraoperative; Neurosurgical Procedures; Pyruvic Acid; Time Factors | 2002 |
Stimulation of glycolysis in anaerobic elongation of pondweed (Potamogeton distinctus) turions.
Topics: Aerobiosis; Alanine Transaminase; Amino Acids; Anaerobiosis; Carbohydrate Metabolism; Carbon Radioisotopes; Glucose; Glycolysis; Lactic Acid; Magnoliopsida; Nitrogen; Oxygen; Plant Stems; Plastids; Polysaccharides; Pyruvic Acid; Starch | 2002 |
Haemodynamic and metabolic effects of low daily dose sulphonylureas in diabetic dog hearts.
Topics: Animals; Blood Glucose; Blood Pressure; Coronary Circulation; Diabetes Mellitus, Experimental; Dogs; Female; Glyburide; Heart; Heart Rate; Hemodynamics; Hypoglycemic Agents; Lactic Acid; Male; Myocardial Contraction; Potassium; Pyruvic Acid; Sulfonylurea Compounds | 2002 |
Chronic corticosteroid administration causes mitochondrial dysfunction in skeletal muscle.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adrenal Cortex Hormones; Case-Control Studies; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Electron Transport Complex I; Electron Transport Complex II; Electron Transport Complex III; Exercise Test; Female; Humans; Lactic Acid; Male; Middle Aged; Mitochondria; Multienzyme Complexes; Muscle, Skeletal; NADH, NADPH Oxidoreductases; Oxidative Stress; Oxidoreductases; Pyruvic Acid; Succinate Dehydrogenase; Time Factors | 2002 |
Variation in organic acids content during ripening of pickled white cheese.
Topics: Acetic Acid; Acids, Heterocyclic; Butyric Acid; Carboxylic Acids; Cheese; Chromatography, High Pressure Liquid; Citric Acid; Fermentation; Food Technology; Formates; Lactic Acid; Orotic Acid; Propionates; Pyruvic Acid; Regression Analysis; Time Factors; Uric Acid | 2002 |
Phosphite dehydrogenase: a versatile cofactor-regeneration enzyme.
Topics: Kinetics; L-Lactate Dehydrogenase; Lactic Acid; NAD; NADH, NADPH Oxidoreductases; NADP; Pyruvic Acid; Thermodynamics | 2002 |
Impact of adding 5.5 mM glucose to SOF medium on the development, metabolism and quality of in vitro produced bovine embryos from the morula to the blastocyst stage.
Topics: Animals; Apoptosis; Blastocyst; Cattle; Culture Media; Embryonic and Fetal Development; Energy Metabolism; Fertilization in Vitro; Glucose; In Vitro Techniques; Lactic Acid; Morula; Oxygen Consumption; Pyruvic Acid | 2002 |
Kinetic and mechanistic investigations on reductions of aflatoxins by lactic acid.
Topics: Aflatoxins; Aspergillus; Carcinogens; Chromatography, Thin Layer; Free Radical Scavengers; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Oxidation-Reduction; Pyruvic Acid | 2002 |
Futile cycles revisited: a markov chain model of simultaneous glycolysis and gluconeogenesis.
Topics: Animals; Cells, Cultured; Computer Simulation; Gluconeogenesis; Glucose; Glycerol; Glycolysis; Hepatocytes; Lactic Acid; Male; Markov Chains; Models, Biological; Pyruvic Acid; Rats; Rats, Wistar; Substrate Cycling | 2002 |
Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine.
Topics: Acid-Base Equilibrium; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blood Pressure; Caspases; Glutathione; Glutathione Disulfide; Lactic Acid; Liver; Microdialysis; Mitochondria; NAD; NADP; Osmolar Concentration; Oxidation-Reduction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyruvic Acid; Shock, Hemorrhagic; Swine | 2002 |
Improved monospermic fertilization and subsequent blastocyst formation of bovine oocytes fertilized in vitro in a medium containing NaCl of decreased concentration.
Topics: Animals; Blastocyst; Cattle; Cell Nucleus; Cells, Cultured; Culture Media; Female; Fertilization; Fertilization in Vitro; Glucose; Lactic Acid; Oocytes; Pyruvic Acid; Sodium Chloride | 2002 |
Sperm binding to epithelial oviduct explants in bulls with different nonreturn rates investigated with a new in vitro model.
Topics: Animals; Benzimidazoles; Carbocyanines; Cattle; Cryopreservation; Culture Media; Culture Techniques; Epithelium; Female; Fertilization in Vitro; Fluorescent Dyes; HEPES; Image Processing, Computer-Assisted; Isotonic Solutions; Lactic Acid; Male; Microscopy, Fluorescence; Oviducts; Pyruvic Acid; Semen Preservation; Serum Albumin, Bovine; Spermatozoa | 2002 |
Microdialysis measurements demonstrate a shift to nonoxidative glucose metabolism in rat pancreatic islets transplanted beneath the renal capsule.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Glucose; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Lactic Acid; Male; Microdialysis; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Inbred WF | 2002 |
Does tissue oxygen-tension reliably reflect cerebral oxygen delivery and consumption?
Topics: Animals; Blood Gas Analysis; Brain; Brain Chemistry; Cerebrovascular Circulation; Electron Transport Complex IV; Electrophysiology; Glutamic Acid; Ischemia; Kinetics; Lactic Acid; Male; Oxidation-Reduction; Oxygen; Oxygen Consumption; Pyruvic Acid; Rabbits; Spectroscopy, Near-Infrared | 2002 |
Experimental pancreatitis causes acute perturbation of energy metabolism in the intestinal wall.
Topics: Animals; Area Under Curve; Energy Metabolism; Glucose; Intestine, Small; Lactic Acid; Liver; Male; Microdialysis; Pancreas; Pancreatitis; Pyruvic Acid; Rats | 2002 |
Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain Diseases; Corpus Striatum; Endotoxins; Escherichia coli; Glutamic Acid; Glycerol; Hydrogen-Ion Concentration; Hypoxia; Lactic Acid; Microdialysis; Nicotine; Oxygen; Pyruvic Acid; Swine; Tumor Necrosis Factor-alpha | 2002 |
Effects of hypothermia on myocardial substrate selection.
Topics: Animals; Coronary Circulation; Fatty Acids; Hypothermia, Induced; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Pyruvic Acid; Rats; Substrate Specificity | 2002 |
Culture environment modulates maturation and metabolism of human oocytes.
Topics: Cells, Cultured; Cellular Senescence; Culture Media; Female; Humans; Lactic Acid; Oocytes; Pyruvic Acid | 2002 |
Amplifying the cellular reduction potential of Streptococcus zooepidemicus.
Topics: Acetates; Adenosine Triphosphate; Catalysis; Cells, Cultured; Cloning, Molecular; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genetic Engineering; Hyaluronic Acid; Lactic Acid; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Pyruvic Acid; Recombinant Fusion Proteins; Reproducibility of Results; Sensitivity and Specificity; Species Specificity; Streptococcus equi | 2003 |
pH is decreased in transplanted rat pancreatic islets.
Topics: Animals; Blood Glucose; Body Weight; Hydrogen; Hydrogen-Ion Concentration; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Lactic Acid; Male; Oxygen; Partial Pressure; Pyruvic Acid; Rats; Rats, Inbred WF; Transplantation, Heterotopic | 2003 |
Early cerebral hyperglycolysis after subarachnoid haemorrhage correlates with favourable outcome.
Topics: Adolescent; Adult; Aged; Blood Glucose; Brain; Embolization, Therapeutic; Energy Metabolism; Female; Glasgow Outcome Scale; Glycolysis; Humans; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Microsurgery; Middle Aged; Prognosis; Pyruvic Acid; Subarachnoid Hemorrhage; Survival Rate | 2002 |
Long-time microdialysis in a patient with meningoencephalitis.
Topics: Adult; Brain Edema; Combined Modality Therapy; Diuretics, Osmotic; Glucose; Glutamic Acid; Glycerol; Humans; Intracranial Pressure; Lactic Acid; Magnetic Resonance Imaging; Male; Mannitol; Meningoencephalitis; Microdialysis; Pyruvic Acid; Respiration, Artificial; Respiratory Tract Infections; Tomography, X-Ray Computed | 2002 |
Intraperitoneal microdialysis for detection of splanchnic metabolic disorders.
Topics: Animals; Ascitic Fluid; Cryoprotective Agents; Disease Models, Animal; Extracellular Space; Gastrointestinal Diseases; Glycerol; Hypoxia; Lactic Acid; Male; Metabolic Diseases; Microdialysis; Peritoneal Dialysis; Postoperative Complications; Pyruvic Acid; Rats; Surgical Procedures, Operative | 2002 |
Pyruvate reverses metabolic effects produced by hypoxia in glioma and hepatoma cell cultures.
Topics: Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Glioma; Glucose; Humans; Hypoxia; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats | 2002 |
Tissue-specific response to interstitial angiotensin II in humans.
Topics: Adipose Tissue; Adult; Angiotensin II; Enzyme Inhibitors; Extracellular Space; Glycolysis; Humans; Lactic Acid; Lipolysis; Male; Microdialysis; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Organ Specificity; Perfusion; Pyruvic Acid; Regional Blood Flow | 2003 |
Intracerebral microdialysis and CSF hydrodynamics in idiopathic adult hydrocephalus syndrome.
Topics: Aged; Blood Glucose; Brain; Brain Ischemia; Cerebrospinal Fluid; Cerebrospinal Fluid Shunts; Female; Glutamic Acid; Humans; Hydrocephalus; Intracranial Arteriosclerosis; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen Consumption; Pyruvic Acid | 2003 |
Effects of endurance training on the gluconeogenic capacity of periportal and perivenous hepatocytes.
Topics: Alanine; Animals; Cell Separation; Female; Gluconeogenesis; Glutamate-Ammonia Ligase; Hepatic Veins; Hepatocytes; Kinetics; Lactic Acid; Physical Conditioning, Animal; Physical Endurance; Portal Vein; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2003 |
Subcutaneous microdialysis for metabolic monitoring in abdominal aortic surgery.
Topics: Aged; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomarkers; Constriction; Glycerol; Humans; Ischemia; Lactic Acid; Leg; Microdialysis; Middle Aged; Monitoring, Intraoperative; Pyruvic Acid; Shoulder; Subcutaneous Tissue | 2002 |
[Study on the organic acids metabolism in Candida glycerolgenesis under different fermentation conditions].
Topics: Acetates; Bioreactors; Candida; Fermentation; Glycerol; Hydrogen-Ion Concentration; Lactic Acid; Oleic Acid; Pyruvic Acid | 2001 |
Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Caloric Restriction; Fructosediphosphates; Glucose; Glycolysis; Lactic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Phosphofructokinase-1; Pyruvic Acid | 2003 |
Cerebrospinal fluid lactate and pyruvate concentrations and their ratio in children: age-related reference intervals.
Topics: Adolescent; Child; Child, Preschool; Female; Hospitals, Pediatric; Humans; Infant; Infant, Newborn; Inpatients; Lactic Acid; Male; Pyruvic Acid; Reference Values; Retrospective Studies | 2003 |
Copper sulphate (CuSO4) toxicity on tissue phosphatases activity and carbohydrates turnover in Achatina fulica.
Topics: Animals; Carbohydrate Metabolism; Copper Sulfate; Dose-Response Relationship, Drug; Emetics; Glycogen; Lactic Acid; Phosphoric Monoester Hydrolases; Pyruvic Acid; Snails; Tissue Distribution | 2002 |
Local energy depletion in the basal forebrain increases sleep.
Topics: 2,4-Dinitrophenol; Adenosine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Dose-Response Relationship, Drug; Electroencephalography; Energy Metabolism; Enzyme Inhibitors; Lactic Acid; Male; Microdialysis; Potassium Cyanide; Prosencephalon; Pyruvic Acid; Rats; Sleep; Sleep Deprivation; Sleep Stages; Uncoupling Agents | 2003 |
The urea cycle in the liver of arthritic rats.
Topics: Ammonia; Animals; Arthritis, Experimental; Aspartic Acid; Citrulline; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Kidney; Lactic Acid; Liver; Male; Models, Biological; Oxygen; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Time Factors; Urea | 2003 |
Biochemical tissue monitoring during hypoxia and reoxygenation.
Topics: Acidosis; Animals; Blood Pressure; Hypoxia; Lactic Acid; Liver; Male; Microdialysis; Muscle, Skeletal; Oxygen; Oxygen Inhalation Therapy; Peritoneum; Pyruvic Acid; Rats; Subcutaneous Tissue | 2003 |
In situ proton NMR analysis of alpha-alkynoate biotransformations. From 'invisible' substrates to detectable metabolites.
Topics: Acetaldehyde; Acetic Acid; Alkynes; Biotransformation; Cell Division; Fatty Acids, Unsaturated; Keto Acids; Lactic Acid; Magnetic Resonance Spectroscopy; Propionates; Protons; Pseudomonas putida; Pyruvic Acid; Spectrophotometry, Ultraviolet | 2003 |
Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case report.
Topics: Adult; Angioplasty, Balloon; Blood Flow Velocity; Blood Glucose; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Angiography; Energy Metabolism; Glutamic Acid; Humans; Intracranial Aneurysm; Lactic Acid; Male; Oxygen Consumption; Postoperative Complications; Pyruvic Acid; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2003 |
Fructose-1,6-bisphosphate for improved outcome after hypothermic circulatory arrest in pigs.
Topics: Animals; Brain Chemistry; Brain Ischemia; Calcium; Creatine Kinase; Creatine Kinase, MB Form; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fructosediphosphates; Glucose; Glycerol; Heart Arrest, Induced; Hypothermia, Induced; Infusions, Intravenous; Isoenzymes; Lactic Acid; Neuroprotective Agents; Phosphorus; Pyruvic Acid; Random Allocation; Sodium; Survival Analysis; Swine; Time Factors; Treatment Outcome | 2003 |
Microdialysis in cisterna magna during cerebral air embolism in swine.
Topics: Animals; Brain; Cisterna Magna; Embolism, Air; Female; Glutamic Acid; Glycerol; Intracranial Embolism; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Swine | 2002 |
Metabolic engineering of Lactobacillus fermentum for production of mannitol and pure L-lactic acid or pyruvate.
Topics: Bioreactors; Cloning, Molecular; Gene Silencing; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Lactobacillus; Mannitol; Protein Engineering; Pyruvic Acid; Recombinant Proteins | 2003 |
Use of the mannitol pathway in fructose fermentation of Oenococcus oeni due to limiting redox regeneration capacity of the ethanol pathway.
Topics: Aldehyde-Lyases; Carbon Dioxide; Culture Media; Ethanol; Fermentation; Fructose; Gram-Positive Cocci; Lactic Acid; Leuconostoc; Mannitol; NADP; Oxidation-Reduction; Pantothenic Acid; Pyruvic Acid; Substrate Specificity | 2003 |
Hypothermia attenuates circulatory shock and cerebral ischemia in experimental heatstroke.
Topics: Animals; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebrovascular Circulation; Corpus Striatum; Frontal Lobe; Glutamic Acid; Glycerol; Heat Stroke; Hippocampus; Hypothalamus; Hypothermia, Induced; Lactic Acid; Male; Microdialysis; Neurons; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Shock | 2003 |
Monocarboxylates and glucose utilization as energy substrates in rat brain slices under selective glial poisoning--a 31P NMR study.
Topics: Animals; Brain; Carboxylic Acids; Glucose; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Models, Biological; Neuroglia; Potassium; Pyruvic Acid; Rats; Rats, Wistar; Time Factors | 2003 |
Peroxisomal membrane monocarboxylate transporters: evidence for a redox shuttle system?
Topics: Animals; Biological Transport; Fatty Acids; Female; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; Models, Chemical; Monocarboxylic Acid Transporters; Oxidation-Reduction; Peroxisomes; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Symporters | 2003 |
Effects of nebivolol on ischemia-induced metabolic changes in dog hearts.
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Carbohydrate Metabolism; Dogs; Endothelium, Vascular; Energy Metabolism; Enzyme Inhibitors; Ethanolamines; Female; Heart; Hemodynamics; Lactic Acid; Male; Myocardial Ischemia; Myocardium; Nebivolol; NG-Nitroarginine Methyl Ester; Pyruvic Acid; Stereoisomerism; Vasodilation | 2003 |
Hyperoxia: good or bad?
Topics: Animals; Blood Glucose; Brain Concussion; Energy Metabolism; Humans; Lactic Acid; Oxygen Inhalation Therapy; Oxyhemoglobins; Pyruvic Acid; Treatment Outcome | 2003 |
Lack of improvement in cerebral metabolism after hyperoxia in severe head injury: a microdialysis study.
Topics: Adolescent; Adult; Aged; Blood Glucose; Brain; Brain Concussion; Diffuse Axonal Injury; Energy Metabolism; Female; Glutamic Acid; Humans; Intensive Care Units; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen Consumption; Oxygen Inhalation Therapy; Pyruvic Acid; Treatment Outcome | 2003 |
Co-fermentation of glucose and citrate by Lactococcus lactis diacetylactis: quantification of the relative metabolic rates by isotopic analysis at natural abundance.
Topics: Acetates; Acetoin; Citric Acid; Diacetyl; Fermentation; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Lactococcus lactis; Pyruvic Acid; Temperature | 2003 |
Response of a strict anaerobe to oxygen: survival strategies in Desulfovibrio gigas.
Topics: Adenosine Triphosphate; Anaerobiosis; Bacterial Proteins; Catalase; Desulfovibrio; Energy Metabolism; Heat-Shock Proteins; Lactic Acid; Oxidative Phosphorylation; Oxidative Stress; Oxygen; Pyruvic Acid; Sulfates | 2003 |
Differential modulation of glucose, lactate, and pyruvate oxidation by insulin and dichloroacetate in the rat heart.
Topics: Acetyl Coenzyme A; Alanine; Animals; Buffers; Citric Acid Cycle; Dichloroacetic Acid; Energy Metabolism; Glucose; Heart; Heart Function Tests; Heart Rate; Hypoglycemic Agents; In Vitro Techniques; Insulin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2003 |
Effects of lactate/pyruvate on synaptic plasticity in the hippocampal dentate gyrus.
Topics: Action Potentials; Animals; Dentate Gyrus; Glucose; Guinea Pigs; In Vitro Techniques; Lactic Acid; Neuronal Plasticity; Pyruvic Acid | 2003 |
Intraperitoneal microdialysis (IPM): a new technique for monitoring intestinal ischemia studied in a porcine model.
Topics: Animals; Catheterization; Disease Models, Animal; Female; Glucose; Glycerol; Intestinal Mucosa; Intestines; Ischemia; Lactic Acid; Ligation; Microdialysis; Monitoring, Physiologic; Peritoneal Dialysis; Pyruvic Acid; Splanchnic Circulation; Swine | 2003 |
Influence of oocyte-secreted factors and culture duration on the metabolic activity of bovine cumulus cell complexes.
Topics: Animals; Cattle; Cells, Cultured; Culture Media; DNA; Female; Glucose; Lactic Acid; Oocytes; Oogenesis; Oxygen Consumption; Pyruvic Acid; Second Messenger Systems; Time; Zona Pellucida | 2003 |
Enhanced energy metabolism during cold hypoxic organ preservation: studies on rat liver after pyruvate supplementation.
Topics: Adenosine; Adenosine Triphosphate; Alanine; Allopurinol; Animals; Cryopreservation; Dose-Response Relationship, Drug; Drug Combinations; Energy Metabolism; Glutathione; Insulin; Lactic Acid; Liver; Male; Organ Preservation Solutions; Osmolar Concentration; Pyruvic Acid; Raffinose; Rats; Rats, Sprague-Dawley; Succinic Acid | 2003 |
The effect of acetate pathway mutations on the production of pyruvate in Escherichia coli.
Topics: Acetates; Escherichia coli; Fermentation; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Mutation; Pyruvic Acid; Temperature | 2003 |
Protective effect of urinary trypsin inhibitor on myocardial mitochondria during hemorrhagic shock and reperfusion.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Blood Transfusion, Autologous; Energy Metabolism; Glycoproteins; Heart Rate; Lactic Acid; Male; Mitochondria, Heart; Mitochondrial Diseases; Myocardial Reperfusion Injury; Oxidation-Reduction; Phosphocreatine; Pyruvic Acid; Rats; Rats, Wistar; Shock, Hemorrhagic; Stroke Volume | 2003 |
Exercise and recovery metabolism in the Pacific spiny dogfish (Squalus acanthias).
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Alanine; Ammonia; Analysis of Variance; Animals; Basal Metabolism; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Coenzyme A; Creatine; Dogfish; Electric Stimulation; Energy Metabolism; Female; Glucose; Glycogen; Hydrogen-Ion Concentration; Lactic Acid; Male; Muscle Fatigue; Muscle Fibers, Fast-Twitch; Oxygen; Partial Pressure; Perfusion; Phosphocreatine; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2003 |
Effects of cerebral air embolism on brain metabolism in pigs.
Topics: Animals; Brain; Carbon Dioxide; Cerebral Cortex; Embolism, Air; Female; Glucose; Hydrogen-Ion Concentration; Intracranial Embolism; Intracranial Pressure; Lactic Acid; Male; Oxygen; Pyruvic Acid; Swine | 2003 |
Glucagon-like peptide-1 (7-36) amide prevents the accumulation of pyruvate and lactate in the ischemic and non-ischemic porcine myocardium.
Topics: Animals; Area Under Curve; Blood Glucose; Cardiovascular System; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Ischemia; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardium; Peptide Fragments; Protein Precursors; Pyruvic Acid; Reperfusion Injury; Swine; Time Factors | 2003 |
Improved developmental competence of cloned porcine embryos with different energy supplements and chemical activation.
Topics: Animals; Cloning, Organism; Culture Media; Electric Stimulation; Glucose; Lactic Acid; Pyruvic Acid; Swine | 2003 |
Pitfalls in the measurement of some intermediary metabolites.
Topics: 3-Hydroxybutyric Acid; Artifacts; Biomarkers; Diagnostic Techniques and Procedures; Fatty Acids, Nonesterified; Humans; Lactic Acid; Metabolism, Inborn Errors; Predictive Value of Tests; Pyruvic Acid; Sensitivity and Specificity | 2003 |
By-product formation by a novel glycerol-producing yeast, Candida glycerinogenes, with different O2 supplies.
Topics: Acetic Acid; Candida; Ethanol; Glucose; Glycerol; Ketoglutaric Acids; Lactic Acid; Oxygen; Pyruvic Acid; Species Specificity; Sulfites; Zea mays | 2003 |
Bedside biochemical monitoring of the penumbra zone surrounding an evacuated acute subdural haematoma.
Topics: Cerebral Cortex; Glucose; Glutamic Acid; Glycerol; Hematoma, Subdural, Acute; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Time Factors; Tomography, X-Ray Computed | 2003 |
Pyruvate shuttle in muscle cells: high-affinity pyruvate transport sites insensitive to trans-lactate efflux.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport, Active; Cell Line; Dose-Response Relationship, Drug; Lactic Acid; Muscle Fibers, Skeletal; Muscle, Skeletal; Phenylpropionates; Protein Binding; Pyruvic Acid; Rats; Reproducibility of Results; Sensitivity and Specificity; Signal Transduction | 2003 |
[Synaptic utilization of lactate/pyruvate and neural function in the aging].
Topics: Aging; Animals; Brain; Glucose; Guinea Pigs; Hippocampus; Lactic Acid; Neurons; Pyruvic Acid; Synapses | 2003 |
Mechanisms of pyruvate inhibition of oxidant-induced apoptosis in human endothelial cells.
Topics: Acetates; Aminooxyacetic Acid; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cell Nucleus; Cell Survival; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydrogen Peroxide; Infant, Newborn; Lactic Acid; Models, Biological; Oxidants; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyruvic Acid; Signal Transduction; Transcriptional Activation; Tumor Suppressor Protein p53; Umbilical Veins | 2003 |
The positive inotropic and calcium-mobilizing effects of growth hormone-releasing peptides on rat heart.
Topics: Animals; Animals, Newborn; Biological Transport; Calcium; Cells, Cultured; Coronary Circulation; Growth Hormone-Releasing Hormone; Heart; Heart Rate; In Vitro Techniques; Lactic Acid; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Peptide Fragments; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2003 |
Metabolic characterization of the bovine blastocyst, inner cell mass, trophectoderm and blastocoel fluid.
Topics: Amino Acids; Analysis of Variance; Animals; Blastocyst; Blastoderm; Cattle; Cell Count; Cells, Cultured; Embryonic Development; Female; Glucose; Intracellular Fluid; Lactic Acid; Pregnancy; Pyruvic Acid; Trophoblasts | 2003 |
The action of oxybutynin on haemodynamics and metabolism in the perfused rat liver.
Topics: Adenine Nucleotides; Animals; Calcium; Glucose; Glucose-6-Phosphate; Hemodynamics; In Vitro Techniques; Lactic Acid; Liver; Male; Mandelic Acids; Muscarinic Antagonists; Pyruvic Acid; Rats; Rats, Wistar | 2003 |
[The distribution of lactic and pyruvic acids in the bovine crystalline lens].
Topics: Animals; Cattle; Lactic Acid; Lens, Crystalline; Pyruvates; Pyruvic Acid | 1952 |
Metabolism of cardiac muscle. IV. Utilization of pyruvate and DL-Lactate by duck heart.
Topics: Animals; Ducks; Heart; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid | 1952 |
Metabolism of cardiac muscle. VI. Competition between L(+)-Lactate uniformly labeled with C14 and C14-carbonyl-labeled pyruvate.
Topics: Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid | 1952 |
[Effect of x-rays on the content of pyruvate and lactate of the blood and on the glycolysis of the bone marrow].
Topics: Blood; Bone Marrow; Glycolysis; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Radiation; X-Rays | 1952 |
[Studies on glycemia and lactic acid and pyruvic acid in the blood in chronic amebiasis before, during, and after emetine therapy].
Topics: Amebiasis; Blood Glucose; Dysentery, Amebic; Emetine; Humans; Intestines; Lactic Acid; Pyruvates; Pyruvic Acid | 1953 |
[Blood glucose, phosphorus, pyruvic acid and lactic acid levels after glucose administration in induced pyrexia].
Topics: Blood; Blood Glucose; Fever; Glucose; Hyperthermia, Induced; Lactic Acid; Phosphorus; Phosphorus, Dietary; Pyruvates; Pyruvic Acid | 1953 |
[Metabolic action of the Cardiac Glycosides. III. Influence of Ouabain on the Utilization of C14-Labeled Glucose, Lactate, and Pyruvate by Dog Heart Slices].
Topics: Animals; Cardiac Glycosides; Dogs; Glucose; Heart; Humans; Lactates; Lactic Acid; Myocardium; Ouabain; Pyruvates; Pyruvic Acid | 1953 |
Effect of electroshock therapy on blood lactic acid and pyruvic acid.
Topics: Blood; Convulsive Therapy; Electricity; Electroconvulsive Therapy; Lactic Acid; Pyruvates; Pyruvic Acid | 1953 |
[Study of simultaneous curves of glucose pyruvic acid and lactic acid in blood after second intravenous administration of glucose in normal and diabetic subjects].
Topics: Administration, Intravenous; Blood; Diabetes Mellitus; Glucose; Glucose Tolerance Test; Humans; Lactic Acid; Pyruvates; Pyruvic Acid | 1953 |
[Modifications of lactic and pyruvic acids in the blood and cerebrospinal fluid in cranial trauma].
Topics: Blood; Cerebrospinal Fluid; Craniocerebral Trauma; Humans; Lactic Acid; Pyruvates; Pyruvic Acid; Wounds and Injuries | 1952 |
Lactic and pyruvic acid relations in frog muscle.
Topics: Animals; Anura; Lactic Acid; Muscles; Musculoskeletal Physiological Phenomena; Pyruvates; Pyruvic Acid; Ranidae; Temperature | 1954 |
Metabolism of cardiac muscle. VII. The effect of inhibitors of the metabolism of pyruvate and DL-lactate.
Topics: Biochemical Phenomena; Fluorides; Iodoacetates; Lactates; Lactic Acid; Malonates; Myocardium; Pyruvates; Pyruvic Acid | 1954 |
[Study of variations of blood sugar, pyruvic acid and lactic acid levels during surgery and anesthesia].
Topics: Anesthesia; Blood; Blood Glucose; Humans; Lactic Acid; Pyruvates; Pyruvic Acid; Surgical Procedures, Operative | 1954 |
[The oxidation of lactic acid, pyruvic acid, and other components of the citric acid cycle by homogenates of corneal epithelium].
Topics: Citric Acid Cycle; Cornea; Epithelium, Corneal; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1954 |
[The role of pyruvic acid in intermediary metabolism; pyruvic acid after glucose load].
Topics: Biochemical Phenomena; Blood; Glucose; Glucose Tolerance Test; Humans; Lactic Acid; Pyruvates; Pyruvic Acid | 1954 |
Studies on obesity. II. Blood pyruvate and lactate curves in obese and normal subjects after ingestion of glucose.
Topics: Blood; Eating; Glucose; Humans; Lactates; Lactic Acid; Obesity; Pyruvates; Pyruvic Acid | 1956 |
Effect of intravenous administration of lactate on blood pyruvate level in man.
Topics: Administration, Intravenous; Blood; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1956 |
Control of concentration gradients of pyruvate and lactate across cell membranes in blood.
Topics: Cell Membrane; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1956 |
[Significance of changes in blood lactic and pyruvic acid levels in cardiac decompensation].
Topics: Heart Failure; Lactic Acid; Pyruvates; Pyruvic Acid | 1956 |
[Concentration of lactic acid and pyruvic acid in the blood after administration of potassium atractylate].
Topics: Atractyloside; Lactic Acid; Potassium; Pyruvates; Pyruvic Acid | 1956 |
[Effects of fructose and glucose on succinic dehydrogenase activity, on concentrations of pyridinnucleotides, pyruvate, ketoglutarate and lactate in tissues of normal and scorbutic animals].
Topics: Animals; Electron Transport Complex II; Fructose; Glucose; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Scurvy; Succinate Dehydrogenase | 1956 |
[Pharmacological research on the active principle of Atractylis gummifera. VI. Blood concentrations of lactic acid & pyruvic acid after potassium atractylate administration].
Topics: Atractylis; Atractyloside; Glycosides; Lactic Acid; Potassium; Pyruvates; Pyruvic Acid; Research | 1957 |
[Intra-arterial administration of respiratory enzymes in peripheral arteritis; local changes of lactic acid, pyruvic acid and alpha-ketoglutaric acid levels and of oxygen utilization coefficient].
Topics: Arteritis; Enzyme Therapy; Glutarates; Humans; Ketoglutaric Acids; Lactic Acid; Oxygen; Pyruvates; Pyruvic Acid | 1957 |
[Changes of certain metabolic aspects (pyruvic acid, lactic acid, ketone bodies, lipids) in diabetics treated with hypoglycemic sulfonamides].
Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Ketone Bodies; Lactic Acid; Lipids; Pyruvates; Pyruvic Acid; Sulfanilamide; Sulfanilamides; Sulfonamides | 1957 |
Potentiation of renoprival hypertension by alanine, pyruvate and lactate.
Topics: Alanine; Humans; Hypertension; Hypertension, Renal; Lactates; Lactic Acid; Nephrectomy; Pyruvates; Pyruvic Acid | 1957 |
The effect of some inorganic ions on brain slices metabolizing glucose or pyruvate.
Topics: Brain; Electrolytes; Glucose; Ions; Lactic Acid; Neurochemistry; Oxygen; Pyruvates; Pyruvic Acid | 1957 |
Relationships of pyruvate and lactate during anaerobic metabolism. I. Effects of infusion of pyruvate or glucose and of hyperventilation.
Topics: Glucose; Hyperventilation; Lactates; Lactic Acid; Metabolism; Pyruvates; Pyruvic Acid | 1958 |
Relationships of pyruvate and lactate during anaerobic metabolism. II. Exercise and formation of O-debt.
Topics: Exercise; Hypoxia; Lactates; Lactic Acid; Metabolism; Pyruvates; Pyruvic Acid | 1958 |
Relationships of pyruvate and lactate during anaerobic metabolism. III. Effect of breathing low-oxygen gases.
Topics: Gases; Hypoxia; Lactates; Lactic Acid; Metabolism; Oxygen; Pyruvates; Pyruvic Acid | 1958 |
[Effect of carbutamide and tolbutamide serum glucose, pyruvic acid, lactic acid and ketone bodies in oral glucose tolerance test].
Topics: Carbutamide; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Ketone Bodies; Lactic Acid; Pyruvates; Pyruvic Acid; Tolbutamide | 1958 |
[Blood content of pyruvic acid, 1(+)-lactic acid & alpha-ketoglutaric acid during radiotherapy].
Topics: Humans; Keto Acids; Ketoglutaric Acids; Ketones; Lactic Acid; Pyruvates; Pyruvic Acid; X-Rays | 1958 |
[Studies on rigor mortis by dinitrophenols. XI. Lactic acid & pyruvic acid content in muscles of albino rats subjected to lethal poisoning by 1,2,4-dinitrophenol & 1,2,6-dinitrophenol].
Topics: 2,4-Dinitrophenol; Animals; Death; Dinitrophenols; Lactic Acid; Muscles; Nitrophenols; Pyruvates; Pyruvic Acid; Rats; Rigor Mortis | 1958 |
[Variations in blood levels of pyruvic acid & lactic acid in patients with simple & hyperfunctioning goiter treated surgically].
Topics: Goiter; Goiter, Endemic; Goiter, Nodular; Humans; Hyperthyroidism; Lactic Acid; Pyruvates; Pyruvic Acid | 1958 |
[Behavior of arterial lactic acid, pyruvic acid & citric acid in normal & pathological subjects].
Topics: Arteries; Citrates; Citric Acid; Lactic Acid; Pyruvates; Pyruvic Acid | 1958 |
[Research on the blood pyruvic acid and lactic acid levels in diabetics treated with carbutamide and tolbutamide].
Topics: Carbutamide; Diabetes Mellitus; Humans; Hypoglycemic Agents; Lactic Acid; Pyruvates; Pyruvic Acid; Research; Tolbutamide | 1958 |
Relationship of pyruvate and lactate during anaerobic metabolism. IV. Local tissue components of total body O2-debt.
Topics: Cell Respiration; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Respiration | 1959 |
Interaction of glycolytic and mitochondrial enzyme systems. II. The reaction sequences: fructose diphosphate to 3-phosphoglyceric acid; and pyruvate to lactate, carbon dioxide and water.
Topics: Carbon Dioxide; Diphosphates; Fructose; Glycerophosphates; Glycolysis; Hexosephosphates; Lactates; Lactic Acid; Mitochondria; Myocardium; Pyruvates; Pyruvic Acid; Water | 1959 |
[2,4-DNP inhibition of enzymatic conversion of 2-phospho-enol-pyruvic acid into lactic acid].
Topics: 2,4-Dinitrophenol; Biochemical Phenomena; Lactic Acid; Nitrophenols; Phosphates; Pyruvates; Pyruvic Acid | 1959 |
Effect of whole body gamma radiation on hepatic LDH activity, lactate, pyruvate concentration and rate of oxygen consumption in Bufo melanostictus.
Topics: Animals; Bufonidae; Dose-Response Relationship, Radiation; Gamma Rays; L-Lactate Dehydrogenase; Lactic Acid; Liver; Oxygen Consumption; Pyruvic Acid; Whole-Body Irradiation | 2002 |
Effect of glucagon and epinephrine on regional metabolism of glucose, pyruvate, lactate, and citrate in normal conscious dogs.
Topics: Animals; Citric Acid; Dogs; Epinephrine; Glucagon; Glucose; Lactates; Lactic Acid; Metabolism; Pyruvates; Pyruvic Acid | 1961 |
[On the problem of cryptogenetic processes of brain atrophy: quantitative measurements of cerebral circulation and cerebral glucose, lactic acid and pyruvic acid metabolism].
Topics: Atrophy; Brain; Brain Diseases; Cerebrovascular Circulation; Glucose; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1961 |
Relationship of pyruvate and lactate during anaerobic metabolism. V. Coronary adequacy.
Topics: Coronary Vessels; Heart; Humans; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid | 1961 |
[The content of pyruvic acid and lactic acid in bovine and rabbit crystalline lens in relation to the amount of glucose in the nutrient solution and following injury by roentgen rays].
Topics: Animals; Cattle; Glucose; Lactates; Lactic Acid; Lens, Crystalline; Pyruvates; Pyruvic Acid; Rabbits; Radiation Injuries, Experimental; X-Rays | 1961 |
Cerebral metabolism of glucose-3-C14, pyruvate-1-C14 and lactate-1-C14 in mental disease.
Topics: Brain; Glucose; Humans; Lactates; Lactic Acid; Neurochemistry; Psychotic Disorders; Pyruvates; Pyruvic Acid | 1961 |
Humoral changes in arteriosclerosis. Investigations on lipids, fatty acids, ketone bodies, pyruvic acid, lactic acid, and glucose in the blood.
Topics: Arteriosclerosis; Blood Glucose; Fatty Acids; Glucose; Humans; Ketone Bodies; Lactates; Lactic Acid; Lipids; Pyruvates; Pyruvic Acid | 1960 |
[Studies of intermediate metabolism in myotonic dystrophy (lactic acid, pyruvic acid, lactic dehydrogenase and malic acid dehydrogenase)].
Topics: Humans; Lactates; Lactic Acid; Malate Dehydrogenase; Malates; Myotonic Dystrophy; Oxidoreductases; Pyruvates; Pyruvic Acid | 1961 |
[On the metabolism of injured tissues. 11. Pyridine nucleotide content, lactic acid content, and pyruvic acid content of the liver of normal and alloxan-diabetic mice after glucose and fructose loading].
Topics: Alloxan; Animals; Coenzymes; Diabetes Mellitus, Experimental; Fructose; Glucose; Lactates; Lactic Acid; Liver; Mice; Nucleotides; Pyridines; Pyruvates; Pyruvic Acid | 1960 |
Studies on the oxidative metabolism of Saccharomyces cerevisiae. II. Morphology and oxidative phosphorylation capacity of mitochondria and derived particles from baker's yeast.
Topics: Cell Respiration; Citric Acid Cycle; Lactates; Lactic Acid; Malates; Metabolism; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Succinates; Succinic Acid; Yeasts | 1961 |
The role of pyruvate in the oxidation of glucose and lactate.
Topics: Carbohydrate Metabolism; Glucose; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1961 |
[Changes in the blood levels of proteins, fatty acids, pyruvic acid and lactic acid during physical effect according to the degree of training].
Topics: Blood Proteins; Fatty Acids; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Sports | 1960 |
[Lactic acid, pyruvic acid, and citric acid in "blood"].
Topics: Citrates; Citric Acid; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1961 |
[Behavior of blood sugar, blood pyruvate and blood lactic acid after oral glucose loading in 30 elderly diabetics].
Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus; Glucose Tolerance Test; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1959 |
[Behavior of the blood sugar, blood pyruvate and blood lactic acid after insulin loading in a group of 10 elderly diabetics].
Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus; Glucose Tolerance Test; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1959 |
Blood pyruvate and lactate response of normal subjects to dextrose, sucrose, and liquid glucose.
Topics: Glucose; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Sucrose | 1960 |
Studies on the peripheral circulation and metabolism in man. II. Oxygen utilization and lactate-pyruvate formation in the legs at rest and during exercise in patients with arteriosclerosis obliterans.
Topics: Arteriosclerosis; Arteriosclerosis Obliterans; Exercise; Humans; Lactates; Lactic Acid; Leg; Male; Oxygen; Pyruvates; Pyruvic Acid; Rest | 1962 |
Evidence for ternary-complex formation with rabbit-muscle lactic acid dehydrogenase, diphosphopyridine nucleotide and pyruvic acid.
Topics: Animals; Coenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Muscles; NAD; Oxidoreductases; Pyruvates; Pyruvic Acid; Rabbits | 1961 |
Effect of epinephrine on lactate, pyruvate, and excess lactate production in normal human subjects.
Topics: Epinephrine; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1961 |
The redox-potential of the lactate-pyruvate system in blood as an indicator of the functional state of cellular oxidation.
Topics: Humans; Lactates; Lactic Acid; Metabolism; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1962 |
[Changes of serum lactic and pyruvic acid in hypoxia and hypercapnea, especially effects of respiratory changes of blood PH upon lactic acid level].
Topics: Carbon Dioxide; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1962 |
[Action of human STH on blood phosphorus, pyruvic acid, lactic acid, alpha-ketoglutaric acid and ATP in man].
Topics: Adenosine Triphosphate; Growth Hormone; Human Growth Hormone; Humans; Ketoglutaric Acids; Lactates; Lactic Acid; Male; Phosphorus; Phosphorus, Dietary; Pyruvates; Pyruvic Acid | 1963 |
[The action of DOCA on the arteriovenous blood sugar-pyruvic-alcohol-lactic acid sequence in liver patients].
Topics: Blood Chemical Analysis; Blood Glucose; Carbohydrate Metabolism; Desoxycorticosterone; Desoxycorticosterone Acetate; Ethanol; Humans; Lactates; Lactic Acid; Liver Diseases; Pyruvates; Pyruvic Acid | 1962 |
The metabolic pattern of the brain in brain perfusion experiments in vivo. II. Pyruvate and lactate formation from C-14-labelled aspartate.
Topics: Aspartic Acid; Brain; Lactates; Lactic Acid; Perfusion; Pyruvates; Pyruvic Acid | 1963 |
The regional metabolism of lactate and pyruvate during exercise in patients with rheumatic heart disease.
Topics: Exercise; Humans; Lactates; Lactic Acid; Physical Exertion; Pyruvates; Pyruvic Acid; Rheumatic Heart Disease | 1962 |
Relations between the cardio-respiratory effects of exercise and the arterial concentration of lactate and pyruvate in patients with rheumatic heart disease.
Topics: Cell Respiration; Exercise; Heart; Humans; Lactates; Lactic Acid; Physical Exertion; Pyruvates; Pyruvic Acid; Respiration; Rheumatic Heart Disease | 1962 |
Regulation of lactate and pyruvate levels in perfusion medium by the isolated rat liver.
Topics: Animals; Lactates; Lactic Acid; Liver; Perfusion; Pyruvates; Pyruvic Acid; Rats | 1962 |
[Effect of the liver on the extracellular lactate/pyruvate redox quotient. Experiments on the isolated perfused rat liver].
Topics: Animals; Extracorporeal Circulation; Lactates; Lactic Acid; Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1963 |
Pyruvate and lactate excretion in patients with diabetes mellitus and benign glycosuria.
Topics: Diabetes Mellitus; Glycosuria; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1963 |
Studies on the peripheral circulation and metabolism in man. III. Oxygen utilization and lactate-pyruvate formation in the legs at rest and during exercise in subjects with hyperkinetic circulation and low physical working capacity (vasoregulatory astheni
Topics: Asthenia; Exercise; Humans; Lactates; Lactic Acid; Leg; Male; Metabolism; Oxygen; Physical Examination; Physical Exertion; Pyruvates; Pyruvic Acid; Rest; Vascular Diseases; Work | 1962 |
[On the enzymatic determination of pyruvic acid and lactic acid in the cerebrospinal fluid of the normal subject].
Topics: Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1963 |
Lactate and pyruvate catabolism in acetic acid bacteria.
Topics: Acetates; Acetic Acid; Acetobacter; Bacteria; Lactates; Lactic Acid; Pseudomonas; Pyruvates; Pyruvic Acid | 1962 |
Conversion of DL-lactate-2-C14 or -3-C14 or pyruvate-2-C14 to blood glucose in humans: effects of diabetes, insulin, tolbutamide, and glucose load.
Topics: Blood Glucose; Diabetes Mellitus; Glucose; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Tolbutamide | 1963 |
Myocardial lactate and pyruvate metabolism.
Topics: Humans; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid; Stress, Physiological | 1962 |
METABOLIC ROLE OF THE BR FACTOR IN BUTYRIBACTERIUM RETTGERI.
Topics: Acetates; Carbohydrate Metabolism; Carbon Dioxide; Eubacterium; Fermentation; Glucose; Lactates; Lactic Acid; Manometry; Pyruvates; Pyruvic Acid; Research; Thioctic Acid | 1963 |
EFFECT OF ELECTROSHOCK AND THIAMINE ON CEREBRAL LACTIC ACID AND PYRUVIC ACID CONTENT OF THE RAT BRAIN.
Topics: Brain; Convulsive Therapy; Electricity; Electroconvulsive Therapy; Electroshock; Lactates; Lactic Acid; Pharmacology; Pyruvates; Pyruvic Acid; Rats; Research; Thiamine | 1963 |
LACTATE, PYRUVATE, GLUCOSE, AND FREE FATTY ACID IN MIXED VENOUS AND ARTERIAL BLOOD.
Topics: Blood Chemical Analysis; Blood Glucose; Brachial Artery; Cardiac Catheterization; Fatty Acids; Fatty Acids, Nonesterified; Glucose; Heart Diseases; Humans; Lactates; Lactic Acid; Lipids; Pulmonary Artery; Pyruvates; Pyruvic Acid | 1963 |
URINARY EXCRETION OF PYRUVIC ACID AND LACTIC ACID IN PREMATURE AND FULL-TERM NEWBORN INFANTS.
Topics: Abruptio Placentae; Female; Humans; Infant, Newborn; Infant, Premature; Lactates; Lactic Acid; Pre-Eclampsia; Pregnancy; Pregnancy, Multiple; Pyruvates; Pyruvic Acid; Urine | 1963 |
[DIISOPROPYLAMMONIUM DICHLOROETHANOATE IN PERIPHERAL VASCULAR DISEASE. EXPERIMENTAL STUDY OF THE CHANGES IN BLOOD SUGAR, PYRUVIC ACID AND LACTIC ACID].
Topics: Acetates; Ammonium Compounds; Arteriosclerosis Obliterans; Blood Chemical Analysis; Blood Glucose; Humans; Lactates; Lactic Acid; Peripheral Vascular Diseases; Pharmacology; Pyruvates; Pyruvic Acid; Quaternary Ammonium Compounds; Vascular Diseases | 1963 |
EFFECT OF ANOXIA ON LACTATE/PYRUVATE AND ATP/ADP RATIOS IN ADULT AND FETAL GUINEA PIG LIVER.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Fetus; Guinea Pigs; Hypoxia; Lactates; Lactic Acid; Liver; Metabolism; Pyruvates; Pyruvic Acid; Research | 1964 |
BLOOD LACTATE, PYRUVATE AND LACTATE-PYRUVATE RATIOS IN CONGENITAL HEART DISEASE.
Topics: Blood Chemical Analysis; Child; Heart Defects, Congenital; Humans; Hypoxia; Lactates; Lactic Acid; NAD; Oximetry; Pyruvates; Pyruvic Acid | 1964 |
PATHWAYS OF CARBOHYDRATE FORMATION IN MAN. III. DISTRIBUTION LABELING OF BLOOD GLUCOSE BY DL-LACTATE-2-14C OR PYRUVATE-2-14C IN DIABETIC AND NONDIABETIC SUBJECTS.
Topics: Blood; Blood Glucose; Carbohydrate Metabolism; Carbon Isotopes; Diabetes Mellitus; Drug Therapy; Glucose; Humans; Hydrocortisone; Insulin; Lactates; Lactic Acid; Leuconostoc; Male; Pyruvates; Pyruvic Acid; Transferases | 1964 |
[KETOSIS IN FEBRILE DISEASE. I. GLYCEMIA, PYRUVIC ACID, LACTIC ACID, ALPHAGLUTARIC ACID, NONESTERIFIED FATTY ACIDS AND KETONEMIA IN FEVER].
Topics: Blood Chemical Analysis; Blood Glucose; Child; Fatty Acids; Fatty Acids, Nonesterified; Fever; Glutarates; Humans; Ketones; Ketosis; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1964 |
A CONVENIENT DEPROTEINIZING PROCEDURE IN THE ENZYMATIC DETERMINATION OF LACTATE AND PYRUVATE IN WHOLE BLOOD.
Topics: Blood Chemical Analysis; Blood Glucose; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Research | 1964 |
[EXPERIMENTAL STUDIES ON EXTRACORPOREAL CIRCULATION, ESPECIALLY ON BLOOD GAS CONTENT, SERUM LACTIC ACID, AND PYRUVIC ACID].
Topics: Blood Chemical Analysis; Blood Gas Analysis; Dogs; Extracorporeal Circulation; Heart; Heart, Artificial; Hypothermia; Hypothermia, Induced; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Research | 1963 |
PROLONGED ANOXIC SURVIVAL DUE TO ANOXIA PRE-EXPOSURE: BRAIN ATP, LACTATE, AND PYRUVATE.
Topics: Adenosine Triphosphate; Brain; Brain Chemistry; Carbohydrate Metabolism; Glucose; Glycolysis; Hypoxia; Iodoacetates; Lactates; Lactic Acid; Metabolism; Pyruvates; Pyruvic Acid; Rats; Research; Telencephalon | 1964 |
CHRONIC ACIDOSIS DUE TO AN ERROR IN LACTATE AND PYRUVATE METABOLISM. REPORT OF TWO CASES.
Topics: Acetoacetates; Acidosis; Blood; Blood Gas Analysis; Carbohydrate Metabolism; Carbohydrate Metabolism, Inborn Errors; Epinephrine; Fructose; Glucagon; Glucose Tolerance Test; Humans; Indians, North American; Infant; Insulin; Intellectual Disability; Ketoglutaric Acids; Lactates; Lactic Acid; Methylene Blue; Muscular Diseases; Obesity; Pantothenic Acid; Penicillamine; Pyruvates; Pyruvic Acid; Seizures; Thiamine; United States | 1964 |
LACTATE-DEGRADING SYSTEM IN BUTYRIBACTERIUM RETTGERI SUBJECT TO GLUCOSE REPRESSION.
Topics: Culture Media; Eubacterium; Fructose; Glucose; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Metabolism; NAD; Oxidation-Reduction; Oxidoreductases; Pyruvates; Pyruvic Acid; Research; Thioctic Acid; United States | 1964 |
IN VIVO INFLUENCES OF HYDROGEN IONS ON LACTATE AND PYRUVATE OF BLOOD.
Topics: Acetates; Acidosis; Bicarbonates; Blood; Carbohydrate Metabolism; Cats; Glucose; Hydrochloric Acid; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Malates; Oxidation-Reduction; Pharmacology; Protons; Pyruvates; Pyruvic Acid; Research; Tromethamine | 1964 |
LACTATE-PYRUVATE STUDIES IN ISCHEMIC FEET.
Topics: Blood; Foot Diseases; Ischemia; Lactates; Lactic Acid; Peripheral Vascular Diseases; Pyruvates; Pyruvic Acid; Vascular Diseases | 1964 |
SERUM PYRUVATE AND LACTATE IN UREMIA.
Topics: Blood Chemical Analysis; Coenzyme A; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Uremia | 1964 |
LACTATE AND PYRUVATE GRADIENTS BETWEEN RED BLOOD CELLS AND PLASMA DURING ACUTE ASPHYXIA.
Topics: Asphyxia; Biological Transport; Blood; Cell Membrane Permeability; Erythrocytes; Glucose; Guinea Pigs; Lactates; Lactic Acid; Plasma; Pyruvates; Pyruvic Acid; Research | 1964 |
MOVEMENTS OF LACTATE AND PYRUVATE IN THE PREGNANT UTERUS OF THE HUMAN.
Topics: Biomedical Research; Blood; Female; Fetus; Humans; Lactates; Lactic Acid; Maternal-Fetal Exchange; Placenta; Pregnancy; Pyruvates; Pyruvic Acid; Uterus | 1964 |
MATERNAL LACTATE, PYRUVATE, AND EXCESS LACTATE PRODUCTION DURING LABOR AND DELIVERY.
Topics: Blood; Carbohydrate Metabolism; Delivery, Obstetric; Drug Therapy; Female; Humans; Labor, Obstetric; Lactates; Lactic Acid; Pregnancy; Pyruvates; Pyruvic Acid | 1964 |
[ATP-ADP- AND LACTATE-PYRUVATE RATIOS IN AEROBIC AND ANEROBIC GLYCOLYSIS IN RABBIT ERYTHROCYTES].
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Erythrocytes; Glycolysis; Lactates; Lactic Acid; Lagomorpha; Pyruvates; Pyruvic Acid; Rabbits; Research | 1964 |
HUMAN CEREBRAL LACTATE AND PYRUVATE EXTRACTION. I. CONTROL SUBJECTS.
Topics: Blood Chemical Analysis; Brain; Brain Chemistry; Carbohydrate Metabolism; Cerebral Arteries; Cranial Sinuses; Glucose; Humans; Hypoxia, Brain; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1965 |
[ON THE INTERMEDIATE METABOLISM OF SORBITOL IN CHILDHOOD. 3. ALTERATION OF KETONE BODIES, PYRUVIC ACID, LACTIC ACID, ALKALI RESERVE AND INORGANIC PHOSPHATE IN THE BLOOD].
Topics: Acidosis; Alkalies; Bicarbonates; Blood Chemical Analysis; Child; Fructose; Humans; Infant; Ketone Bodies; Lactates; Lactic Acid; Metabolism; Phosphates; Pyruvates; Pyruvic Acid; Sorbitol | 1964 |
PYRUVATE AND LACTATE LEVELS IN RELATIONSHIP TO THE NICOTINAMIDE--ADENINE DINUCLEOTIDE LEVELS IN MALARIAL PARASITES (PLASMODIUM BERGHEI).
Topics: Adenine; Animals; Erythrocytes; Glucose; L-Lactate Dehydrogenase; Lactates; Lactic Acid; N-Glycosyl Hydrolases; NAD; Niacinamide; Parasites; Phenylhydrazines; Plasmodium; Plasmodium berghei; Pyruvates; Pyruvic Acid; Rats; Research; Reticulocytes | 1964 |
THE EFFECT OF HYPOXIA ON GAS EXCHANGE AND ARTERIAL LACTATE AND PYRUVATE CONCENTRATION DURING MODERATE EXERCISE IN MAN.
Topics: Arteries; Blood; Carbon Dioxide; Exercise; Humans; Hydrogen-Ion Concentration; Hyperventilation; Hypoxia; Lactates; Lactic Acid; Male; Metabolism; Oxygen; Physical Exertion; Pyruvates; Pyruvic Acid | 1965 |
THE ACID-BASE STATUS IN CYANOTIC CONGENITAL HEART DISEASE.
Topics: Acid-Base Equilibrium; Acidosis; Blood Gas Analysis; Cardiac Output; Heart Defects, Congenital; Humans; Hypoxia; Infant; Infant, Newborn; Lactates; Lactic Acid; Metabolism; Oxygen Consumption; Prognosis; Pyruvates; Pyruvic Acid | 1965 |
LACTATE/PYRUVATE RATIO OF UMBILICAL VEIN BLOOD.
Topics: Anesthesia; Anesthesia, Obstetrical; Blood Chemical Analysis; Delivery, Obstetric; Female; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Labor, Obstetric; Lactates; Lactic Acid; Metabolism; Pharmacology; Pregnancy; Pyruvates; Pyruvic Acid; Umbilical Cord; Umbilical Veins | 1965 |
BLOOD LACTATE AND PYRUVATE AND EVIDENCE FOR HYPOCAPNIC LACTICACIDOSIS IN THE CHICKEN.
Topics: Acidosis; Animals; Bicarbonates; Blood Gas Analysis; Blood Glucose; Carbon Dioxide; Chickens; Hyperventilation; Hypocapnia; Lactates; Lactic Acid; Poultry; Pyruvates; Pyruvic Acid; Research; Toxicology | 1965 |
REFRACTORY SEPTIC SHOCK IN MAN. ROLE OF LACTATE AND PYRUVATE METABOLISM AND ACID-BASE BALANCE IN PROGNOSIS.
Topics: Acid-Base Equilibrium; Acidosis; Humans; Lactates; Lactic Acid; Male; Metabolism; Prognosis; Pyruvates; Pyruvic Acid; Shock; Shock, Septic | 1965 |
RATE OF UTILIZATION OF GLUCOSE AND 'COMPARTMENTATION' OF ALPHA-OXOGLUTARATE AND GLUTAMATE IN RAT BRAIN.
Topics: Alanine; Amino Acids; Blood; Blood Glucose; Brain; Brain Chemistry; Chemistry Techniques, Analytical; Glucose; Glutamates; Glutamic Acid; Glycolysis; Ketoglutaric Acids; Kinetics; Lactates; Lactic Acid; Liver; Pyruvates; Pyruvic Acid; Rats; Research | 1965 |
[Behavior of sugar, pyruvic acid and lactic acid in blood in lymphadenosis and chronic myeloid leukemia].
Topics: Blood Glucose; Humans; Lactic Acid; Leukemia; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphatic Vessels; Pyruvates; Pyruvic Acid | 1955 |
Thiamine deficiency and the in vivo oxidation of lactate and pyruvate labeled with carbon.
Topics: Carbon; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Thiamine; Thiamine Deficiency; Vitamin B Deficiency | 1960 |
[The influence of physical work on the behavior of lactic acid, pyruvic acid and citric acid in the blood].
Topics: Citrates; Citric Acid; Humans; Lactates; Lactic Acid; Leadership; Physical Examination; Physical Exertion; Pyruvates; Pyruvic Acid; Work | 1960 |
[A new determination of the redox potential of the lactate-pyruvate system].
Topics: Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1960 |
[On the glucose, lactic acid and pyruvic acid metabolism of the isolated pulmonary lobe perfused by a donor dog].
Topics: Animals; Carbohydrate Metabolism; Dogs; Glucose; Lactates; Lactic Acid; Lung; Pyruvates; Pyruvic Acid | 1959 |
[An optical-enzymatic determination of L-lactic acid and pyruvic acid in the single parts of young and old crystalline lens of cattle].
Topics: Animals; Cattle; Lactates; Lactic Acid; Lens, Crystalline; Pyruvates; Pyruvic Acid | 1960 |
[Behavior of blood sugar, blood pyruvate and blood lactic acid after oral sulfanylurea loading in 34 diabetics].
Topics: Blood Glucose; Diabetes Mellitus; Humans; Hypoglycemic Agents; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1959 |
A study in man of cerebral blood flow and cerebral glucose, lactate and pyruvate metabolism before and after eating.
Topics: Brain; Cerebrovascular Circulation; Glucose; Humans; Hunger; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid | 1959 |
Movements of lactate and pyruvate in pregnant uterus.
Topics: Female; Humans; Lactates; Lactic Acid; Movement; Pregnancy; Pyruvates; Pyruvic Acid; Uterus | 1962 |
Oxygen debt, lactate, pyruvate, and excess lactate after muscular work.
Topics: Humans; Lactates; Lactic Acid; Metabolism; Muscles; Oxygen; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid | 1962 |
Uptake of lactate and pyruvate by intact kidney of the dog.
Topics: Animals; Biochemical Phenomena; Dogs; Humans; Kidney; Lactates; Lactic Acid; Metabolism; Pyruvates; Pyruvic Acid | 1962 |
[The effect of thiamine on the lactic acid and pyruvic acid content of the rat brain].
Topics: Animals; Brain; Brain Chemistry; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Rats; Thiamine | 1962 |
Hexose monophosphate, pyruvate and lactate in the peripheral blood in glycogen-storage disease type I.
Topics: Glycogen; Glycogen Storage Disease; Hexosephosphates; Hexoses; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1962 |
Actions of quercetin on gluconeogenesis and glycolysis in rat liver.
Topics: Animals; Glucokinase; Gluconeogenesis; Glucose; Glycolysis; In Vitro Techniques; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Phosphorylation; Pyruvic Acid; Quercetin; Rats; Rats, Wistar | 2003 |
In vitro nutritional requirements and metabolic products of pathogenic and nonpathogenic strains of Cryptobia salmositica: essential carbohydrates and amino acids.
Topics: Alanine Transaminase; Amino Acids; Analysis of Variance; Animals; Aspartate Aminotransferases; Carbon Dioxide; Cells, Cultured; Disaccharidases; In Vitro Techniques; Kinetoplastida; Lactic Acid; Monosaccharides; Pyruvic Acid | 2003 |
Human intraperitoneal microdialysis: increased lactate/pyruvate ratio suggests early visceral ischaemia. A pilot study.
Topics: Aged; Aged, 80 and over; Colonic Neoplasms; Female; Humans; Intestines; Ischemia; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Postoperative Complications; Pyruvic Acid; Splanchnic Circulation | 2003 |
Glucose deprivation produces a prolonged increase in sensitivity to glutamate in cultured rat cortical neurons.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dose-Response Relationship, Drug; Drug Resistance; Glucose; Glutamic Acid; Glycolysis; Lactic Acid; Mitochondria; Neurons; Oligomycins; Oxidative Phosphorylation; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Uncoupling Agents | 2003 |
Description and interpretation of adaptive evolution of Escherichia coli K-12 MG1655 by using a genome-scale in silico metabolic model.
Topics: Adaptation, Physiological; Biological Evolution; Computational Biology; Culture Media; Escherichia coli; Genome, Bacterial; Hot Temperature; Ketoglutaric Acids; Lactic Acid; Models, Biological; Phenotype; Pyruvic Acid | 2003 |
1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects.
Topics: Animals; Dose-Response Relationship, Drug; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Necrosis; Phosphorus Isotopes; Pyruvic Acid; Rats; Rats, Wistar; Serine; Time Factors; Urine | 2003 |
Mitochondrial and metabolic effects of nucleoside reverse transcriptase inhibitors (NRTIs) in mice receiving one of five single- and three dual-NRTI treatments.
Topics: Aminoisobutyric Acids; Animals; Blotting, Northern; Cholesterol; DNA; Fatty Acids; Immunoblotting; Ketone Bodies; Lactic Acid; Lipid Metabolism; Liver; Male; Metabolism; Mice; Mitochondria; Oxidation-Reduction; Phospholipids; Pyruvic Acid; Reverse Transcriptase Inhibitors; Thymidine; Triglycerides; Zidovudine | 2003 |
Enhanced survival effect of pyruvate correlates MAPK and NF-kappaB activation in hydrogen peroxide-treated human endothelial cells.
Topics: Acetates; Aminooxyacetic Acid; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Cytosol; Endothelium, Vascular; Glutathione; Humans; Hydrogen Peroxide; Lactic Acid; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidants; Oxidative Stress; Pyruvic Acid; Umbilical Veins | 2004 |
The effect of crude and purified Cerastes vipera venom protein fractions on respiratory chain function in cultured human fibroblasts.
Topics: Animals; Cell Line; Citrate (si)-Synthase; Electron Transport; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Humans; Lactic Acid; Pyruvic Acid; Viper Venoms | 2003 |
Neurochemical monitoring using intracerebral microdialysis during cardiac resuscitation.
Topics: Adult; Biomarkers; Brain Chemistry; Cause of Death; Cerebral Infarction; Energy Metabolism; Fatal Outcome; Glycerol; Glycolysis; Heart Arrest; Heart Massage; Humans; Hypoxia, Brain; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Pulmonary Embolism; Pyruvic Acid | 2004 |
Cerebral glucose and oxygen metabolism in patients with fulminant hepatic failure.
Topics: Acetoacetates; Brain; Humans; Lactic Acid; Liver Cirrhosis; Liver Failure; Oxygen; Oxygen Consumption; Pyruvic Acid | 2003 |
Novel tyrosine-phosphorylated post-pyruvate metabolic enzyme, dihydrolipoamide dehydrogenase, involved in capacitation of hamster spermatozoa.
Topics: Acrosome Reaction; Amino Acid Sequence; Animals; Calcium; Cricetinae; Dihydrolipoamide Dehydrogenase; Enzyme Inhibitors; Glucose; Indoles; Lactic Acid; Male; Mesocricetus; Molecular Sequence Data; Phosphorylation; Pyruvic Acid; Sperm Capacitation; Spermatozoa; Time Factors; Tyrosine | 2004 |
The effect of pfl gene knockout on the metabolism for optically pure D-lactate production by Escherichia coli.
Topics: Acetate Kinase; Acetyltransferases; Adenosine Triphosphate; Aerobiosis; Alcohol Dehydrogenase; Energy Metabolism; Escherichia coli; Fructose; Genes, Bacterial; Gluconates; Glucose; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenase (NADP+)(Phosphorylating); Glycerol; Glycolysis; Isomerism; L-Lactate Dehydrogenase; Lactic Acid; Mutation; Phosphoenolpyruvate Carboxylase; Phosphogluconate Dehydrogenase; Pyruvate Kinase; Pyruvic Acid | 2004 |
Serum L-lactate and pyruvate in HIV-infected patients with and without presumed NRTI-related adverse events compared to healthy volunteers.
Topics: Adult; Anti-HIV Agents; DNA, Mitochondrial; Female; HIV Infections; HIV-1; Humans; Lactic Acid; Male; Mitochondria; Pyruvic Acid; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine | 2004 |
Effect of hypervolaemic haemodilution on cerebral glutamate, glycerol, lactate and free radicals in heatstroke rats.
Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Free Radicals; Glutamic Acid; Glycerol; Heat Stroke; Hemodilution; Lactic Acid; Lipid Peroxidation; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serum Albumin | 2004 |
Changes in plasma lactate and pyruvate concentrations after taking a bath in hot deep seawater.
Topics: Adolescent; Adult; Baths; Climatotherapy; Hemoglobins; Humans; Hydrogen-Ion Concentration; Lactic Acid; Male; Nitrates; Nitrogen; Phosphates; Phosphorus; Pyruvic Acid; Salts; Seawater; Silicon; Sodium; Temperature; Time Factors; Water | 2003 |
NADH augments blood flow in physiologically activated retina and visual cortex.
Topics: Animals; Energy Metabolism; Lactic Acid; Male; NAD; NG-Nitroarginine Methyl Ester; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retinal Vessels; Visual Cortex | 2004 |
Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain.
Topics: Adult; Cerebrovascular Circulation; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Photic Stimulation; Pyruvic Acid; Tomography, Emission-Computed | 2004 |
Redox status in very-low birth-weight newborns.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Female; Fetal Growth Retardation; Gluconeogenesis; Glucose; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Very Low Birth Weight; Ketone Bodies; Lactic Acid; Male; Oxidation-Reduction; Prospective Studies; Pyruvic Acid | 2004 |
Delayed neurological deficits detected by an ischemic pattern in the extracellular cerebral metabolites in patients with aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Brain Ischemia; Extracellular Space; Female; Glucose; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Intraoperative; Predictive Value of Tests; Pyruvic Acid; Sensitivity and Specificity; Subarachnoid Hemorrhage | 2004 |
Structure of Toxoplasma gondii LDH1: active-site differences from human lactate dehydrogenases and the structural basis for efficient APAD+ use.
Topics: Animals; Apoenzymes; Binding Sites; Catalysis; Coenzymes; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Muscle, Skeletal; Myocardium; NAD; Oxalic Acid; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyruvic Acid; Substrate Specificity; Toxoplasma | 2004 |
Moderate controlled cortical contusion in pigs: effects on multi-parametric neuromonitoring and clinical relevance.
Topics: Animals; Body Temperature; Brain Edema; Brain Injuries; Disease Models, Animal; Glucose; Glutamic Acid; Intracranial Pressure; Lactic Acid; Male; Monitoring, Physiologic; Oxygen Consumption; Pyruvic Acid; Swine | 2003 |
Glycogen metabolism in the rat retina.
Topics: Animals; Darkness; Dose-Response Relationship, Drug; Glucose; Glycogen; In Vitro Techniques; Lactic Acid; Light; NAD; Pyruvic Acid; Rats; Rats, Long-Evans; Retina; Time Factors | 2004 |
A new mitochondrial DNA mutation in ND3 gene causing severe Leigh syndrome with early lethality.
Topics: Amino Acid Sequence; Animals; Brain; DNA, Mitochondrial; Electron Transport; Electron Transport Complex I; Family Health; Female; Humans; Infant; Lactic Acid; Leigh Disease; Magnetic Resonance Imaging; Male; Molecular Sequence Data; Muscles; Mutation; Polymorphism, Restriction Fragment Length; Proteins; Pyruvic Acid; Sequence Homology, Amino Acid | 2004 |
Pitfalls in the measurement of some intermediary metabolites: stabilization of lactate and pyruvate.
Topics: Artifacts; Diagnostic Techniques and Procedures; Humans; Lactic Acid; Pyruvic Acid; Sensitivity and Specificity | 2004 |
[Cerebral microdialysis in stroke].
Topics: Brain Edema; Critical Care; Diagnostic Imaging; Electrolytes; Energy Metabolism; Glutamic Acid; Glycerol; Humans; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Lactic Acid; Microdialysis; Monitoring, Physiologic; Nerve Tissue Proteins; Neurologic Examination; Neurotransmitter Agents; Oximetry; Oxygen Consumption; Predictive Value of Tests; Prognosis; Pseudotumor Cerebri; Pyruvic Acid; Reference Values; Water-Electrolyte Balance | 2004 |
The metabolism of lactate and pyruvate in children with congenital heart disease.
Topics: Child; Heart; Heart Defects, Congenital; Humans; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1950 |
[The effects of certain products of intermediate metabolism on the heart].
Topics: Heart; Lactic Acid; Pyruvic Acid | 1951 |
The oxidation of lactic acid, pyruvic acid, and various members of the citric-acid cycle by bovine lens homogenates.
Topics: Animals; Cattle; Lactic Acid; Lens, Crystalline; Pyruvic Acid | 1951 |
[Further observations on the content of pyruvic and lactic acid in the vitreous humor].
Topics: Body Fluids; Lactic Acid; Pyruvic Acid; Vitreous Body | 1951 |
Studies on the crystalline lens. IV. Distribution of cytochrome, total riboflavin, lactate, and pyruvate and their metabolic significance.
Topics: Abscess; Cytochromes; Humans; Lactates; Lactic Acid; Lens, Crystalline; Lung; Lung Abscess; Pyruvates; Pyruvic Acid; Riboflavin | 1951 |
Two separate pathways for d-lactate oxidation by Saccharomyces cerevisiae mitochondria which differ in energy production and carrier involvement.
Topics: Adenosine Triphosphate; Antimycin A; Cinnamates; Energy Metabolism; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactate Dehydrogenases; Lactic Acid; Membrane Potentials; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2004 |
Blood glutathione, lactic acid, and pyruvic acid relationships in schizophrenia.
Topics: Exercise; Glutathione; Humans; Lactic Acid; Pyruvic Acid; Schizophrenia | 1952 |
Conversion of C14 labeled propionate, lactate, and pyruvate to acetyl groups in the rat.
Topics: Acetates; Animals; Lactates; Lactic Acid; Propionates; Pyruvates; Pyruvic Acid; Rats | 1952 |
Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators.
Topics: Animals; Antimycin A; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell-Free System; Cyanides; Gluconeogenesis; Glyceraldehyde 3-Phosphate; Humans; L-Lactate Dehydrogenase; Lactic Acid; Malates; Male; Mitochondria, Liver; Models, Biological; Monocarboxylic Acid Transporters; Osmotic Pressure; Oxaloacetic Acid; Oxidation-Reduction; Phenazines; Protons; Pyruvic Acid; Rats; Rats, Wistar; Rotenone; Succinates; Tetramethylphenylenediamine; Uncoupling Agents | 2004 |
Peroxisomal fatty acid oxidation is a substantial source of the acetyl moiety of malonyl-CoA in rat heart.
Topics: Animals; Carbohydrates; Fatty Acids; Glucose; Kinetics; Lactic Acid; Malonyl Coenzyme A; Models, Statistical; Myocardium; Oleic Acid; Palmitic Acid; Perfusion; Peroxisomes; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Comparative effects of vasopressin, norepinephrine, and L-canavanine, a selective inhibitor of inducible nitric oxide synthase, in endotoxic shock.
Topics: Acid-Base Equilibrium; Adenosine Triphosphate; Animals; Canavanine; Energy Metabolism; Enzyme Inhibitors; Hemodynamics; Intestinal Mucosa; Kidney; Lactic Acid; Lung; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Norepinephrine; Permeability; Phosphocreatine; Pyruvic Acid; Rats; Rats, Wistar; Renal Agents; Shock, Septic; Vasoconstrictor Agents; Vasopressins | 2004 |
Experimental evaluation of the influence of complete artificial circulation on renal circulation and tissue metabolism -comparative study of pulsatile vs nonpulsatile circulation.
Topics: Analysis of Variance; Animals; beta 2-Microglobulin; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Heart-Assist Devices; Ketone Bodies; Kidney; Lactic Acid; Pulsatile Flow; Pyruvic Acid; Renal Circulation; Shock, Cardiogenic; Swine; Ventricular Fibrillation | 2003 |
Development of in-vitro-derived bovine embryos in protein-free media: effects of amino acids, glucose, pyruvate, lactate, phosphate and osmotic pressure.
Topics: Amino Acids; Animals; Blastocyst; Cattle; Culture Media, Serum-Free; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Glucose; Lactic Acid; Osmotic Pressure; Phosphates; Pyruvic Acid | 2003 |
Results of intraperitoneal microdialysis depend on the location of the catheter.
Topics: Aged; Blood Glucose; Catheterization; Colectomy; Female; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Peritoneal Cavity; Postoperative Care; Pyruvic Acid | 2004 |
Heterogenic response of the liver parenchyma to ethanol studied in the bivascularly perfused rat liver.
Topics: Animals; Carbon Dioxide; Citric Acid Cycle; Ethanol; Gluconeogenesis; Glucose; Glycolysis; Lactic Acid; Liver; Liver Glycogen; Male; NAD; Oxidation-Reduction; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Wistar | 2004 |
Improved in vitro development of porcine embryos with different energy substrates and serum.
Topics: Animals; Blood; Culture Media; Culture Techniques; Embryonic and Fetal Development; Energy Metabolism; Fertilization in Vitro; Fetal Blood; Lactic Acid; Pyruvic Acid; Serum Albumin, Bovine; Swine | 2004 |
Energy substrate requirements of rat retinal pigmented epithelial cells in culture: relative importance of glucose, amino acids, and monocarboxylates.
Topics: Amino Acids; Animals; Blotting, Western; Cell Culture Techniques; Cell Division; Cell Survival; DNA; Energy Metabolism; Glucose; Immunoblotting; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lactic Acid; Monocarboxylic Acid Transporters; Monosaccharide Transport Proteins; Pigment Epithelium of Eye; Pyruvic Acid; Rats | 2004 |
A (13)C isotopomer kinetic analysis of cardiac metabolism: influence of altered cytosolic redox and [Ca(2+)](o).
Topics: Animals; Aspartic Acid; Calcium; Carbon Isotopes; Citric Acid Cycle; Cytosol; Glutamic Acid; Heart Rate; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; Male; Myocardium; Osmolar Concentration; Oxidation-Reduction; Oxygen Consumption; Pressure; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2004 |
Pyruvate dehydrogenase deficiency in a Sussex spaniel.
Topics: Animals; Diagnosis, Differential; Dog Diseases; Dogs; Female; Lactic Acid; Pedigree; Physical Conditioning, Animal; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid | 2004 |
Compartmentation of glycolysis and glycogenolysis in the perfused rat heart.
Topics: Animals; Energy Metabolism; Glucagon; Glucose; Glutamic Acid; Glycogen; Glycolysis; Heart; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardium; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Signal Transduction | 2004 |
Gas exchange responses to constant work-rate exercise in patients with glycogenosis type V and VII.
Topics: Acidosis, Lactic; Adult; Case-Control Studies; Epinephrine; Exercise; Exercise Test; Exercise Tolerance; Female; Glycogen Storage Disease Type V; Glycogen Storage Disease Type VII; Heart Rate; Humans; Lactic Acid; Male; Norepinephrine; Oxygen Consumption; Pulmonary Gas Exchange; Pyruvic Acid | 2004 |
Blockade of quinolinic acid-induced neurotoxicity by pyruvate is associated with inhibition of glial activation in a model of Huntington's disease.
Topics: Animals; Disease Models, Animal; Drug Administration Routes; Enzyme Inhibitors; Guanidines; Huntington Disease; Lactic Acid; Male; Neostriatum; Neuroglia; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Pyruvic Acid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Tyrosine | 2004 |
Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel.
Topics: Acid Sensing Ion Channels; Amiloride; Amino Acid Substitution; Animals; Degenerin Sodium Channels; Edetic Acid; Epithelial Sodium Channels; Formates; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Lactic Acid; Membrane Potentials; Nerve Tissue Proteins; Oocytes; Patch-Clamp Techniques; Protein Subunits; Protons; Pyruvic Acid; Recombinant Proteins; Sodium; Sodium Channels; Structure-Activity Relationship; Xenopus | 2004 |
Toxic and sub-lethal effects of oleandrin on biochemical parameters of fresh water air breathing murrel, Channa punctatus (Bloch.).
Topics: Acetylcholinesterase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardenolides; Cardiac Glycosides; Dose-Response Relationship, Drug; Glycogen; India; Lactic Acid; Lethal Dose 50; Liver; Muscles; Perciformes; Plant Extracts; Plant Leaves; Pyruvic Acid | 2004 |
Effect of purine-free low-malt liquor (happo-shu) on the plasma concentrations and urinary excretion of purine bases and uridine--comparison between purine-free and regular happo-shu.
Topics: Adult; Beer; Central Nervous System Depressants; Creatinine; Edible Grain; Ethanol; Humans; Lactic Acid; Male; Middle Aged; Purines; Pyrimidines; Pyruvic Acid; Uric Acid; Uridine | 2004 |
Comparison of short- and long-duration oxygen treatment after cerebral asphyxia in newborn piglets.
Topics: Animals; Animals, Newborn; Asphyxia; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Glycerol; Lactic Acid; Laser-Doppler Flowmetry; Microdialysis; Oxygen; Pyruvic Acid; Swine | 2004 |
High-performance liquid chromatographic assay of lactic, pyruvic and acetic acids and lactic acid stereoisomers in calf feces, rumen fluid and urine.
Topics: Acetic Acid; Animals; Body Fluids; Cattle; Chromatography, High Pressure Liquid; Feces; Lactic Acid; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism | 2004 |
Comparative structural analysis and kinetic properties of lactate dehydrogenases from the four species of human malarial parasites.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Coenzymes; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Models, Molecular; Molecular Sequence Data; Molecular Structure; Plasmodium; Protozoan Proteins; Pyruvic Acid; Sequence Alignment; Sequence Homology, Amino Acid | 2004 |
Splanchnic metabolism during gut ischemia and short-term endotoxin and hemorrhagic shock as evaluated by intravasal microdialysis.
Topics: Abdomen; Animals; Endotoxemia; Endotoxins; Glucose; Glycerol; Hemodynamics; Ileum; Ischemia; Lactic Acid; Manometry; Mesentery; Microdialysis; Pyruvic Acid; Reperfusion Injury; Shock, Hemorrhagic; Splanchnic Circulation; Swine | 2004 |
Lactate isotopomer analysis by 1H NMR spectroscopy: consideration of long-range nuclear spin-spin interactions.
Topics: Animals; Carbon Isotopes; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2004 |
Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism.
Topics: Adenosine Triphosphate; Glycogen; Glycolysis; Lactic Acid; Models, Cardiovascular; Myocardial Ischemia; Myocardium; NAD; Oxidation-Reduction; Oxygen Consumption; Phosphocreatine; Phosphorylation; Pyruvic Acid | 2004 |
Mitochondrial encephalomyopathy with lactic acidosis and strokelike episodes (MELAS): a mitochondrial disorder presents as fibromyalgia.
Topics: Aged; Diagnosis, Differential; Female; Fibromyalgia; Humans; Lactic Acid; MELAS Syndrome; Muscle, Skeletal; Pyruvic Acid | 2004 |
Individual value of brain tissue oxygen pressure, microvascular oxygen saturation, cytochrome redox level, and energy metabolites in detecting critically reduced cerebral energy state during acute changes in global cerebral perfusion.
Topics: Algorithms; Animals; Brain Chemistry; Brain Ischemia; Brain Stem; Capillaries; Cerebrovascular Circulation; Cisterna Magna; Cytochromes; Cytochromes a; Cytochromes a3; Electrophysiology; Energy Metabolism; Glutamic Acid; Infusions, Intravenous; Lactic Acid; Male; Oxidation-Reduction; Oximetry; Oxygen Consumption; Polarography; Pyruvic Acid; Rabbits | 2004 |
Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise.
Topics: Acetylcarnitine; Adenosine Triphosphate; Adult; Blood Glucose; Energy Metabolism; Exercise; Glycogen; Glycogen Phosphorylase; Humans; Lactic Acid; Male; Muscle, Skeletal; Oxidation-Reduction; Phosphocreatine; Physical Endurance; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2004 |
Effect of L-carnitine administration on the seminal characteristics of oligoasthenospermic stallions.
Topics: Acetylcarnitine; Animals; Breeding; Carnitine; Carnitine O-Acetyltransferase; Horse Diseases; Horses; Infertility, Male; Lactic Acid; Male; Pyruvic Acid; Semen; Sperm Count; Sperm Motility; Spermatozoa | 2004 |
Intraperitoneal and intraluminal microdialysis in the detection of experimental regional intestinal ischaemia.
Topics: Animals; Catheterization; Constriction; Female; Glucose; Glycerol; Intestine, Small; Ischemia; Jejunum; Lactic Acid; Laser-Doppler Flowmetry; Microdialysis; Peritoneum; Pyruvic Acid; Swine | 2004 |
Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation.
Topics: Acetate Kinase; Acetates; Anaerobiosis; Arginine; Bacterial Proteins; beta-Galactosidase; DNA-Binding Proteins; Fermentation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Reporter; Hydrogen-Ion Concentration; Integration Host Factors; L-Lactate Dehydrogenase; Lactic Acid; Mutation; Nitrates; Oligonucleotide Array Sequence Analysis; Phosphate Acetyltransferase; Promoter Regions, Genetic; Pseudomonas aeruginosa; Pyruvic Acid; Trans-Activators | 2004 |
Lactic acid production with lactate dehydrogenase using the visible light sensitization of zinc porphyrin.
Topics: Animals; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Metalloporphyrins; Myocardium; Oxidation-Reduction; Paraquat; Photobiology; Photosensitizing Agents; Pyruvic Acid; Sus scrofa | 2004 |
Can we distinguish between different types of local perfusion/metabolic derangement by regional venous concentrations of intermediary energy substrates?
Topics: Animals; Endotoxins; Glucose; Glycerol; Lactic Acid; Microdialysis; Perfusion; Pyruvic Acid; Reperfusion; Research Design; Shock; Shock, Hemorrhagic; Time Factors | 2004 |
Flux to acetate and lactate excretions in industrial fermentations: physiological and biochemical implications.
Topics: Acetate Kinase; Acetates; Citric Acid; Coenzyme A; Enzyme Inhibitors; Escherichia coli; Gluconates; Glucose; Isocitrates; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Lactic Acid; Oxidation-Reduction; Phosphate Acetyltransferase; Pyruvates; Pyruvic Acid | 2004 |
Exogenous pyruvate prevents stress-evoked suppression of mitogen-stimulated proliferation.
Topics: Analysis of Variance; Animals; Cell Division; Corticosterone; Dose-Response Relationship, Drug; Down-Regulation; Energy Metabolism; Injections, Intraperitoneal; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitogens; Pyruvic Acid; Restraint, Physical; Spleen; Stress, Psychological | 2004 |
Effect of co-administration of cassava (Manihot esculenta Crantz) rich diet and alcohol in rats.
Topics: Acid Phosphatase; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Cyanides; Diet; Ethanol; gamma-Glutamyltransferase; Glucuronidase; L-Lactate Dehydrogenase; Lactic Acid; Male; Manihot; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Thiocyanates | 2004 |
Biochemical changes elicited by isosaline leaf and stem-bark extracts of Harungana madagascariensis in the rat.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Clusiaceae; Female; Injections, Intraperitoneal; Kidney; Lactic Acid; Liver; Male; Plant Bark; Plant Extracts; Plant Leaves; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Triglycerides; Urea | 2004 |
Patterns of energy substrates during ischemia measured in the brain by microdialysis.
Topics: Adult; Brain Injuries; Brain Ischemia; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Humans; Hypoxia; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Pyruvic Acid; Sensitivity and Specificity | 2004 |
Dobutamine compensates deleterious hemodynamic and metabolic effects of vasopressin in the splanchnic region in endotoxin shock.
Topics: Adrenergic beta-Agonists; Animals; Blood Gas Analysis; Cardiac Output; Dobutamine; Female; Fluid Therapy; Hemodynamics; Hemostatics; Hypotension; Lactic Acid; Microdialysis; Pyruvic Acid; Regional Blood Flow; Shock, Septic; Splanchnic Circulation; Swine; Vasopressins | 2004 |
Biochemical analysis of respiratory function in cybrid cell lines harbouring mitochondrial DNA mutations.
Topics: Adenosine Triphosphate; Blood Platelets; Cell Line; Cell Respiration; Citric Acid; Cytoplasm; DNA, Mitochondrial; Extracellular Matrix; Fibroblasts; Humans; Hybrid Cells; Intracellular Space; Lactic Acid; Mutation; Myoblasts; Oxygen Consumption; Pyruvic Acid | 2004 |
Mitochondrial function in turkey skeletal muscle--impact on meat quality.
Topics: Acidosis; Aging; Animals; Body Composition; Glycolysis; Histocytochemistry; Hydrogen-Ion Concentration; Lactic Acid; Meat; Microscopy, Electron; Mitochondria, Muscle; Muscle, Skeletal; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Postmortem Changes; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Quality Control; Sarcoplasmic Reticulum; Turkeys | 2004 |
Metabolic properties of Eubacterium pyruvativorans, a ruminal 'hyper-ammonia-producing' anaerobe with metabolic properties analogous to those of Clostridium kluyveri.
Topics: Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; Caseins; Clostridium; Crotonates; Energy Metabolism; Eubacterium; Fatty Acids, Volatile; Fermentation; Glycine; Lactic Acid; Leucine; Peptides; Proline; Pyruvic Acid; Rumen; Serine; Threonine | 2004 |
Monocarboxylate transporters in subsarcolemmal and intermyofibrillar mitochondria.
Topics: Animals; Biological Transport; Blotting, Western; Cell Cycle Proteins; Cell Membrane; Kinetics; Lactates; Lactic Acid; Membrane Transport Proteins; Mitochondria, Muscle; Monocarboxylic Acid Transporters; Muscle Proteins; Muscles; Myofibrils; Oncogene Proteins; Oxygen; Protein Isoforms; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; Sarcolemma; Sarcoplasmic Reticulum | 2004 |
Normobaric hyperoxia--induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: a prospective historical cohort-matched study.
Topics: Adolescent; Adult; Aged; Blood Glucose; Brain; Brain Injuries; Cohort Studies; Critical Care; Energy Metabolism; Female; Glasgow Coma Scale; Humans; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Male; Matched-Pair Analysis; Microdialysis; Middle Aged; Oxygen Consumption; Oxygen Inhalation Therapy; Prospective Studies; Pyruvic Acid | 2004 |
Cell volume changes affect gluconeogenesis in the perfused liver of the catfish Clarias batrachus.
Topics: Amino Acids; Animals; Catfishes; Cell Nucleus; Cytosol; Fishes; Gluconeogenesis; Hepatocytes; Lactic Acid; Liver; Male; Mitochondria; Osmosis; Perfusion; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvic Acid; Subcellular Fractions; Water | 2004 |
Metabolic analysis of Corynebacterium glutamicum during lactate and succinate productions under oxygen deprivation conditions.
Topics: Acids; Anaerobiosis; Corynebacterium; DNA, Bacterial; Gene Deletion; Gene Dosage; Genes, Bacterial; Glucose; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; NAD; Phosphoenolpyruvate Carboxylase; Pyruvic Acid; Sequence Analysis, DNA; Sodium Bicarbonate; Succinic Acid | 2004 |
Clostridium jejuense sp. nov., isolated from soil.
Topics: Acetic Acid; Anaerobiosis; Anti-Bacterial Agents; Base Composition; Clostridium; DNA, Bacterial; DNA, Ribosomal; Fermentation; Formates; Genes, rRNA; Glucose; Hydrogen; Hydrogen-Ion Concentration; Korea; Lactic Acid; Molecular Sequence Data; Movement; Phylogeny; Pyruvic Acid; RNA, Bacterial; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sodium Chloride; Soil Microbiology; Spores, Bacterial; Temperature | 2004 |
Pyruvate and lactate content of the blood during and after muscular work.
Topics: Blood; Humans; Lactates; Lactic Acid; Muscles; Pyruvates; Pyruvic Acid | 1950 |
[Role of certain products of intermediate metabolism in cancer].
Topics: Humans; Lactic Acid; Neoplasms; Pyruvic Acid | 1950 |
Pyruvate protection against endothelial cytotoxicity induced by blockade of glucose uptake.
Topics: Animals; Antioxidants; Apoptosis; Cattle; Cell Survival; Cells, Cultured; Cytoprotection; Cytosol; Deoxyglucose; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucose; Glutathione; Kinetics; Lactic Acid; Lipid Peroxidation; Pulmonary Artery; Pyruvic Acid; Thiobarbituric Acid Reactive Substances | 2004 |
The yield of laboratory investigations in children with infantile autism.
Topics: Adolescent; Adult; Amino Acids; Autistic Disorder; Biomarkers; Blood Chemical Analysis; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Fragile X Syndrome; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Pyruvic Acid; Regression, Psychology; Retrospective Studies; Tomography, X-Ray Computed; Urinalysis | 2005 |
Metabolic effects of propofol in the isolated perfused rat liver.
Topics: Alanine; Anesthetics, Intravenous; Animals; Energy Metabolism; Gluconeogenesis; Glycerol; Glycolysis; In Vitro Techniques; Infusions, Intravenous; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxygen; Phosphorylation; Propofol; Pyruvic Acid; Rats; Rats, Wistar; Time Factors | 2004 |
R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase.
Topics: Acetyltransferases; Binding Sites; Dihydrolipoyllysine-Residue Acetyltransferase; Glucose; Humans; Lactic Acid; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase (Lipoamide)-Phosphatase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Thioctic Acid | 2004 |
Epinephrine induces tissue perfusion deficit in porcine endotoxin shock: evaluation by regional CO(2) content gradients and lactate-to-pyruvate ratios.
Topics: Adrenergic Agonists; Animals; Bicarbonates; Carbon Dioxide; Epinephrine; Female; Hemodynamics; Intestines; Lactic Acid; Microdialysis; Norepinephrine; Oxygen Consumption; Pyruvic Acid; Regional Blood Flow; Shock, Septic; Splanchnic Circulation; Swine; Vasoconstrictor Agents | 2005 |
Effect of replacement of pyruvate/lactate in culture medium with glucose on preimplantation development of porcine embryos in vitro.
Topics: Animals; Blastocyst; Culture Media; Embryonic Development; Energy Metabolism; Female; Fertilization in Vitro; Glucose; Lactic Acid; Pyruvic Acid; Sus scrofa | 2004 |
Mitochondrial tissue specificity of substrates utilization in rat cardiac and skeletal muscles.
Topics: Adenosine Diphosphate; Animals; Carnitine; Cell Respiration; Energy Metabolism; Fatty Acids; Glutamic Acid; Glycerophosphates; Glycolysis; Kinetics; Lactic Acid; Malates; Male; Mitochondria; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Oxidative Phosphorylation; Pyruvic Acid; Rats; Rats, Wistar | 2005 |
A family with pyruvate dehydrogenase complex deficiency due to a novel C>T substitution at nucleotide position 407 in exon 4 of the X-linked Epsilon1alpha gene.
Topics: Amino Acid Substitution; Brain; Carnitine; Child, Preschool; Exons; Humans; Infant; Lactic Acid; Leigh Disease; Magnetic Resonance Imaging; Male; Mutation; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid; Siblings | 2005 |
Increase in muscle nociceptive substances and anaerobic metabolism in patients with trapezius myalgia: microdialysis in rest and during exercise.
Topics: Creatine; Female; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Lactic Acid; Microdialysis; Muscle, Skeletal; Occupational Diseases; Pain; Pain Measurement; Physical Exertion; Pyruvic Acid; Regional Blood Flow; Rest; Serotonin; Spectrophotometry; Time Factors; Ultrasonography | 2004 |
Interstitial muscle lactate, pyruvate and potassium dynamics in the trapezius muscle during repetitive low-force arm movements, measured with microdialysis.
Topics: Adult; Arm; Electromyography; Extracellular Space; Humans; Lactic Acid; Male; Microdialysis; Movement; Muscle Contraction; Muscle, Skeletal; Physical Exertion; Potassium; Pyruvic Acid | 2004 |
Metabolic regulation of leptin production in adipocytes: a role of fatty acid synthesis intermediates.
Topics: Adipocytes; Animals; Bezafibrate; Cerulenin; Epididymis; Fatty Acids; In Vitro Techniques; Lactic Acid; Leptin; Male; Malonyl Coenzyme A; Pyruvic Acid; Rats | 2004 |
Energy boost: the Warburg effect returns in a new theory of cancer.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Blood Glucose; Cell Hypoxia; Cytoplasm; DNA-Binding Proteins; Glycolysis; History, 20th Century; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Mitochondria; Neoplasms; Nuclear Proteins; Phosphorylation; Pyruvic Acid; Transcription Factors | 2004 |
Impact of altered substrate utilization on cardiac function in isolated hearts from Zucker diabetic fatty rats.
Topics: Animals; Carbon Isotopes; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids; Glucose; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Obesity; Palmitates; Pyruvic Acid; Rats; Rats, Zucker | 2005 |
Neurochemical monitoring of glycerol therapy in patients with ischemic brain edema.
Topics: Adult; Aged; Brain; Brain Edema; Drug Monitoring; Edema; Female; Glutamic Acid; Glycerol; Humans; Infarction, Middle Cerebral Artery; Intracranial Pressure; Lactic Acid; Male; Middle Aged; Middle Cerebral Artery; Models, Statistical; Osmolar Concentration; Osmosis; Pyruvic Acid; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2005 |
Toxicological effect and biochemical alterations induced by different fractions of Euphorbia royleana latex in freshwater harmful vector snail Lymnaea acuminata.
Topics: Animals; Disease Vectors; Euphorbia; Lactic Acid; Latex; Lymnaea; Molluscacides; Plant Extracts; Pyruvic Acid | 2004 |
Influence of antral follicle size on oocyte characteristics and embryo development in the bovine.
Topics: Animals; Blastocyst; Cattle; Cell Cycle; Embryo, Mammalian; Embryonic Development; Female; Gene Expression Profiling; Kinetics; Lactic Acid; Oocytes; Ovarian Follicle; Oxygen Consumption; Protein Biosynthesis; Pyruvic Acid; Time Factors | 2005 |
Effect of interleukin-10 on newborn piglet brain following hypoxia-ischemia and endotoxin-induced inflammation.
Topics: Animals; Animals, Newborn; Area Under Curve; Brain; Cerebrovascular Circulation; Encephalitis; Endotoxins; Glycerol; Hypoxia-Ischemia, Brain; Interleukin-10; Lactic Acid; Laser-Doppler Flowmetry; Microcirculation; Microdialysis; Osmolar Concentration; Oxygen Consumption; Pyruvic Acid; Swine; Tumor Necrosis Factor-alpha | 2005 |
Blood sampling techniques for lactate and pyruvate estimation: a reappraisal.
Topics: Adult; Blood Specimen Collection; Humans; Lactic Acid; Physical Exertion; Pyruvic Acid; Time Factors; Veins | 1975 |
Cloning and expression of the Clostridium thermocellum L-lactate dehydrogenase gene in Escherichia coli and enzyme characterization.
Topics: Amino Acid Sequence; Cloning, Molecular; Clostridium thermocellum; Enzyme Activation; Enzyme Activators; Enzyme Stability; Escherichia coli; Fructosediphosphates; Gene Expression Regulation, Bacterial; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; Mutation; Open Reading Frames; Promoter Regions, Genetic; Pyruvic Acid; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2004 |
Ontogenetic changes and developmental adjustments in lactate dehydrogenase isozymes of an obligate air-breathing fish Channa punctatus during deprivation of air access.
Topics: Adaptation, Physiological; Air; Animals; Asphyxia; Fishes; Hypoxia; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Larva; Metamorphosis, Biological; Muscle, Skeletal; Myocardium; Pyruvic Acid; Respiration | 2005 |
Cytosolic NADH redox and thiol oxidation regulate pulmonary arterial force through ERK MAP kinase.
Topics: Animals; Cattle; Cell Hypoxia; Cytosol; Diamide; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; L-Lactate Dehydrogenase; Lactic Acid; Mitogen-Activated Protein Kinases; NAD; NADPH Oxidases; Oxidants; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Artery; Pyruvic Acid; Signal Transduction; Stress, Mechanical; Sulfhydryl Compounds | 2005 |
Relative carnitine deficiency in autism.
Topics: Adolescent; Alanine; Autistic Disorder; Carnitine; Child; Child, Preschool; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Hyperammonemia; Lactic Acid; Male; Pyruvic Acid; Retrospective Studies | 2004 |
Physiological responses to sulfide toxicity by the air-breathing catfish, Hoplosternum littorale (Siluriformes, Callichthyidae).
Topics: Animals; Catfishes; Electron Transport Complex IV; Gills; Glucose; Hematologic Tests; Lactic Acid; Liver; Methemoglobin; Muscles; Myocardium; Pyruvic Acid; Sulfides | 2004 |
Fluctuations in bovine ovarian follicular fluid composition throughout the oestrous cycle.
Topics: Amino Acids; Animals; Carbohydrate Metabolism; Carbohydrates; Cattle; Cell Culture Techniques; Culture Media; Estrous Cycle; Female; Follicular Fluid; Glucose; Glutamic Acid; Lactic Acid; Pyruvic Acid | 2005 |
Low-dose terlipressin during long-term hyperdynamic porcine endotoxemia: effects on hepatosplanchnic perfusion, oxygen exchange, and metabolism.
Topics: Animals; Blood Pressure; Cardiac Output; Endotoxemia; Endotoxins; Escherichia coli; Female; Glucose; Hemodynamics; Hydrogen-Ion Concentration; Lactic Acid; Lipopolysaccharides; Liver Circulation; Lypressin; Male; Oxygen; Oxygen Consumption; Pyruvic Acid; Splanchnic Circulation; Swine; Terlipressin; Vascular Resistance; Vasoconstrictor Agents | 2005 |
Gender associations with cerebrospinal fluid glutamate and lactate/pyruvate levels after severe traumatic brain injury.
Topics: Adult; Brain Injuries; Female; Glasgow Coma Scale; Glutamic Acid; Humans; Hypothermia, Induced; Lactic Acid; Male; Pyruvic Acid; Randomized Controlled Trials as Topic; Sex Characteristics | 2005 |
The influence of trauma and ischemia on carbohydrate metabolites monitored in hamster flap tissue.
Topics: Animals; Carbohydrate Metabolism; Cricetinae; Ischemia; Lactic Acid; Male; Mesocricetus; Oxygen; Pyruvic Acid; Regional Blood Flow; Surgical Flaps; Wounds and Injuries | 2005 |
[Effect of intermittent hypoxic training on indices of adaptation to hypoxia in rats during physical exertion].
Topics: Adaptation, Physiological; Animals; Hypoxia; Lactic Acid; Male; Mitochondria, Muscle; Muscle, Skeletal; NAD; Oxidative Phosphorylation; Oxygen Consumption; Physical Exertion; Pyruvic Acid; Rats; Rats, Wistar; Succinate Dehydrogenase | 2004 |
Mitochondrial dysfunction in autism spectrum disorders: a population-based study.
Topics: Adolescent; Autistic Disorder; Child; Comorbidity; Cross-Sectional Studies; Epilepsy; Female; Humans; Intellectual Disability; Lactic Acid; Male; Mass Screening; Mitochondrial Diseases; Neuropsychological Tests; Population Surveillance; Portugal; Pyruvic Acid; Reference Values | 2005 |
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
Topics: Acetylation; Animals; Caloric Restriction; Cyclic AMP; Fasting; Gene Expression Regulation; Gluconeogenesis; Glucose; Glycolysis; Hepatocytes; Homeostasis; Insulin; Lactic Acid; Liver; Longevity; Lysine; Mice; NAD; Nutritional Status; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Binding; Pyruvic Acid; Rats; RNA, Messenger; Sirtuin 1; Sirtuins; Trans-Activators; Transcription Factors | 2005 |
Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury.
Topics: Aldehyde Reductase; Animals; Blotting, Western; Enzyme Activation; Enzyme Inhibitors; Humans; Janus Kinase 2; L-Iditol 2-Dehydrogenase; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Ischemia; Myocardium; Niacin; Oxidation-Reduction; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyruvic Acid; Rats; Rats, Wistar; Signal Transduction; STAT5 Transcription Factor | 2005 |
Glucose, lactate, and pyruvate concentrations in dogs with babesiosis.
Topics: Acid-Base Equilibrium; Animals; Babesiosis; Blood Gas Analysis; Blood Glucose; Blood Pressure Determination; Dog Diseases; Dogs; Hypoglycemia; Lactic Acid; Prospective Studies; Pyruvic Acid; Urinalysis | 2005 |
Accumulation of very long-chain fatty acids does not affect mitochondrial function in adrenoleukodystrophy protein deficiency.
Topics: Adenosine Triphosphate; Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Brain; Cell Fractionation; Cells, Cultured; Diaphragm; Fatty Acids, Nonesterified; Fibroblasts; Glucose; Humans; Lactic Acid; Male; Mice; Mice, Knockout; Mitochondria; Muscle, Skeletal; Oxidative Phosphorylation; Pyruvic Acid; Skin; Subcellular Fractions; X Chromosome | 2005 |
Intracerebral microdialysis in severe brain trauma: the importance of catheter location.
Topics: Adult; Aged; Brain Injuries; Catheters, Indwelling; Child; Female; Glucose; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Pyruvic Acid | 2005 |
New generation of hemoglobin-based oxygen carriers evaluated for oxygenation of critically ischemic hamster flap tissue.
Topics: Animals; Blood Substitutes; Carbohydrate Metabolism; Cattle; Cricetinae; Critical Illness; Disease Models, Animal; Drug Carriers; Glucose; Hemodilution; Hemoglobins; Ischemia; Lactic Acid; Male; Mesocricetus; Microcirculation; Oxygen; Polymers; Prospective Studies; Pyruvic Acid; Surgical Flaps; Treatment Outcome | 2005 |
Resuscitation from experimental heatstroke by hyperbaric oxygen therapy.
Topics: Animals; Biomarkers; Brain Diseases; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; Hyperbaric Oxygenation; Ischemia; Lactic Acid; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Resuscitation; Survival Analysis; Treatment Outcome; Tumor Necrosis Factor-alpha | 2005 |
Energy substrate requirements for survival of rat retinal cells in culture: the importance of glucose and monocarboxylates.
Topics: Animals; Cell Survival; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Glycolysis; Iodoacetates; Lactic Acid; Pyruvic Acid; Rats; Retina | 2005 |
alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation.
Topics: Angiogenesis Inhibitors; Apoptosis; Cell Line, Tumor; Cell Nucleus; Colonic Neoplasms; Cytosol; DNA Fragmentation; Humans; Immunoblotting; Lactates; Lactic Acid; Mitochondria; Nitrobenzoates; Oxidative Stress; Oxygen; Pyruvic Acid; Reactive Oxygen Species; Superoxides; Thioctic Acid; Time Factors | 2005 |
Xenon attenuates cerebral damage after ischemia in pigs.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Body Temperature; Brain; Brain Chemistry; Electroencephalography; Glutamic Acid; Glycerol; Heart Arrest; Hemodynamics; Intracranial Pressure; Ischemic Attack, Transient; Lactic Acid; Microdialysis; Neuroprotective Agents; Oxygen Consumption; Pyruvic Acid; Swine; Xenon | 2005 |
Severe cognitive impairment correlates with higher cerebrospinal fluid levels of lactate and pyruvate in a canine model of senile dementia.
Topics: Aging; Alzheimer Disease; Animals; Behavior, Animal; Biomarkers; Brain Chemistry; Cerebrospinal Fluid Proteins; Chromatography, High Pressure Liquid; Cognition Disorders; Dogs; Energy Metabolism; Female; Ketoglutaric Acids; Lactic Acid; Male; Pyruvic Acid; Spectrophotometry, Ultraviolet | 2005 |
D-lactate metabolism in starved Octopus ocellatus.
Topics: Animals; Energy Metabolism; Enzymes; Extremities; Food Deprivation; Japan; Lactic Acid; Octopodiformes; Pyruvaldehyde; Pyruvic Acid; Spectrophotometry | 2005 |
Ammonia effects on pyruvate/lactate production in astrocytes--interaction with glutamate.
Topics: Ammonia; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Glutamic Acid; Glutamine; Glutathione; Glycolysis; Hyperammonemia; Interneurons; Lactic Acid; Malates; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Pyruvic Acid; Up-Regulation | 2005 |
Pyruvate but not lactate prevents NADH-induced myoglobin oxidation.
Topics: Animals; Antioxidants; Catalase; Dose-Response Relationship, Drug; Free Radicals; Horses; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Myocardium; Myoglobin; NAD; Oxidation-Reduction; Oxygen; Pyruvic Acid; Reperfusion Injury; Time Factors | 2005 |
Determination of lactate dehydrogenase (LDH) activity in milk by a fluorometric assay.
Topics: Animals; Cattle; Copper; Fluorometry; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Logistic Models; Milk; Oxalic Acid; Oxamic Acid; Pyruvic Acid | 2005 |
Metabolic changes in rat striatum following convulsive seizures.
Topics: Animals; Corpus Striatum; Electroshock; Energy Metabolism; Epilepsy; Glucose; Glycolysis; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2005 |
Recovery of pyruvic acid from biotransformation solutions.
Topics: Acinetobacter; Biotechnology; Culture Media; Lactic Acid; Methylamines; Pyruvic Acid; Sodium Hydroxide; Solutions; Water | 2006 |
Nutrient concentrations in murine follicular fluid and the female reproductive tract.
Topics: Amino Acids; Animals; Culture Media; Embryo Culture Techniques; Embryo, Mammalian; Estrus; Fallopian Tubes; Female; Follicular Fluid; Genitalia, Female; Glucose; Lactic Acid; Mice; Oocytes; Ovarian Follicle; Pyruvic Acid; Reproduction; Uterus | 2005 |
Normal values and differences between intraperitoneal and subcutaneous microdialysis in patients after non-complicated gastrointestinal surgery.
Topics: Adult; Aged; Aged, 80 and over; Female; Gastrointestinal Diseases; Glucose; Glycerol; Humans; Ischemia; Lactic Acid; Male; Microdialysis; Middle Aged; Peritoneal Cavity; Postoperative Care; Postoperative Period; Pyruvic Acid; Reference Values; Subcutaneous Tissue | 2005 |
Tricarboxylic acid cycle inhibition by Li+ in the human neuroblastoma SH-SY5Y cell line: a 13C NMR isotopomer analysis.
Topics: Acetyl Coenzyme A; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Carbon Isotopes; Cell Line, Tumor; Cell Survival; Citrate (si)-Synthase; Citric Acid Cycle; Dose-Response Relationship, Drug; Down-Regulation; Energy Metabolism; Feedback, Physiological; Glucose; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Neuroblastoma; Neurons; Pyruvic Acid | 2005 |
Protective effect of buflomedil in a rat model of moderate cerebral ischemia.
Topics: Animals; Blood Glucose; Brain Ischemia; Cell Death; Cerebrovascular Circulation; Hippocampus; Lactic Acid; Male; Phosphopyruvate Hydratase; Pyramidal Cells; Pyrrolidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Telencephalon; Tissue Fixation; Vasodilator Agents | 2005 |
Metabolic engineering of Corynebacterium glutamicum for fuel ethanol production under oxygen-deprivation conditions.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Anaerobiosis; Corynebacterium glutamicum; DNA, Bacterial; Ethanol; Gene Deletion; Gene Expression; Genetic Engineering; Glucose; Hydro-Lyases; Lactic Acid; Molecular Sequence Data; Oxygen; Phosphoenolpyruvate Carboxylase; Promoter Regions, Genetic; Pyruvate Decarboxylase; Pyruvic Acid; Sequence Analysis, DNA; Succinic Acid; Transgenes; Zymomonas | 2004 |
Glucose metabolism heterogeneity in human and mouse malignant glioma cell lines.
Topics: Amino Acid Sequence; Animals; Cell Hypoxia; Cell Survival; Electron Transport; Glioma; Glucose; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Mice; Molecular Sequence Data; Oxidative Phosphorylation; Phenotype; Pyruvic Acid; Sequence Homology, Amino Acid; Tumor Cells, Cultured | 2005 |
Ipsapirone and ketanserin protects against circulatory shock, intracranial hypertension, and cerebral ischemia during heatstroke.
Topics: Anesthesia; Animals; Brain; Brain Ischemia; Corpus Striatum; Disease Models, Animal; Glutamic Acid; Glycerol; Heat Stroke; Hot Temperature; Hypertension; Hypoxia; Intracranial Hypertension; Ketanserin; Lactates; Lactic Acid; Models, Statistical; Neurons; Oxygen; Pressure; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Shock; Temperature; Time Factors; Titanium; Urethane | 2005 |
Lactic acidosis in sepsis: another commentary.
Topics: Acidosis, Lactic; Glucose; Humans; Lactic Acid; Pyruvic Acid; Sepsis | 2005 |
Metabolism, protein content, and in vitro embryonic development of goat cumulus-oocyte complexes matured with physiological concentrations of glucose and L-lactate.
Topics: Animals; Embryonic Development; Female; Fertilization in Vitro; Follicular Fluid; Glucose; Goats; In Vitro Techniques; Lactic Acid; Oocytes; Proteins; Pyruvic Acid | 2006 |
Effect of exogenous carbohydrates in a serum-free culture medium on the development of in vitro matured and fertilized porcine embryos.
Topics: Animals; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Culture Techniques; Dose-Response Relationship, Drug; Embryonic Development; Energy Metabolism; Fertilization in Vitro; Fructose; Glucose; Lactic Acid; Pyruvic Acid; Swine | 2005 |
Dynamic change in energy metabolism by electroacupuncture stimulation in rats.
Topics: Acupuncture Points; Animals; Blood Glucose; Electroacupuncture; Energy Metabolism; Lactic Acid; Meridians; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2005 |
Interference and blood sample preparation for a pyruvate enzymatic assay.
Topics: Adult; Blood Chemical Analysis; Female; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Middle Aged; NAD; Perchlorates; Pyruvic Acid | 2006 |
Depletion of mitochondrial DNA copies/cell in peripheral blood mononuclear cells in HIV-1-infected treatment-naïve patients.
Topics: Adult; Aged; Anti-HIV Agents; Biomarkers; DNA, Mitochondrial; Drug Monitoring; Female; HIV Infections; HIV-1; Humans; Lactic Acid; Leukocytes, Mononuclear; Male; Middle Aged; Pyruvic Acid; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral | 2006 |
Increased glyceroneogenesis in adipose tissue from rats adapted to a high-protein, carbohydrate-free diet: role of dietary fatty acids.
Topics: Adaptation, Physiological; Adipose Tissue; Animals; Chylomicrons; Diet; Dietary Carbohydrates; Dietary Proteins; Fatty Acids; Glutathione Peroxidase; Glycerides; Glycerol; Lactic Acid; Lipoprotein Lipase; Lipoproteins, LDL; Male; Polyethylene Glycols; Pyruvic Acid; Rats; Rats, Wistar | 2006 |
Incorporating expression data in metabolic modeling: a case study of lactate dehydrogenase.
Topics: Cell Line, Tumor; Enzyme Activation; Erythrocytes; Fermentation; Gene Expression Profiling; Humans; Isoenzymes; Lactate Dehydrogenases; Lactic Acid; MAP Kinase Signaling System; Models, Chemical; Pyruvic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Dinitrophenol-induced mitochondrial uncoupling in vivo triggers respiratory adaptation in HepG2 cells.
Topics: 2,4-Dinitrophenol; Adaptation, Physiological; Adenine Nucleotide Translocator 3; Cell Respiration; Cells, Cultured; Electron Transport Complex IV; Gene Expression; Glucose; Humans; Lactic Acid; Membrane Potentials; Mitochondria; Nuclear Respiratory Factor 1; Oxidative Phosphorylation; Pyruvic Acid; Uncoupling Agents; Up-Regulation | 2006 |
Effects of culture media and energy sources on the inhibition of nuclear maturation in bovine oocytes.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Culture Media; Dose-Response Relationship, Drug; Female; Glucose; Glutamine; Hypoxanthine; Lactic Acid; Meiosis; Oocytes; Pyruvic Acid; Species Specificity | 2006 |
Effects of caffeine, halothane, and 4-chloro-m-cresol on skeletal muscle lactate and pyruvate in malignant hyperthermia-susceptible and normal swine as assessed by microdialysis.
Topics: Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blood Gas Analysis; Caffeine; Central Nervous System Stimulants; Creatine Kinase; Cresols; Dose-Response Relationship, Drug; Electrolytes; Glucose; Halothane; Ketamine; Lactic Acid; Malignant Hyperthermia; Microdialysis; Muscle, Skeletal; Propofol; Pyruvic Acid; Ryanodine Receptor Calcium Release Channel; Swine | 2006 |
Anaerobic degradation of di-n-butyl phthalate and di-(2-ethylhexyl) phthalate in sludge.
Topics: Acetates; Anti-Bacterial Agents; Bacteria, Anaerobic; Biodegradation, Environmental; Chlorides; Dibutyl Phthalate; Diethylhexyl Phthalate; Ferric Compounds; Hydrogen-Ion Concentration; Lactic Acid; Manganese Compounds; Metals, Heavy; Oxides; Pyruvic Acid; Sewage; Surface-Active Agents; Temperature; Water Pollutants, Chemical | 2005 |
Biochemical stress response in freshwater fish Channa punctatus induced by aqueous extracts of Euphorbia tirucalli plant.
Topics: Acetylcholinesterase; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; DNA; Electron Transport Complex IV; Euphorbia; Glycogen; Lactic Acid; Latex; Liver; Muscles; Peptide Hydrolases; Perciformes; Plant Extracts; Plant Stems; Proteins; Pyruvic Acid; RNA; Water | 2006 |
Composition of beer by 1H NMR spectroscopy: effects of brewing site and date of production.
Topics: Adenosine; Beer; Dextrins; Environment; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Reproducibility of Results; Time Factors; Tyrosine; Uridine | 2006 |
Mean arterial pressure about 40 mmHg during CPB is associated with cerebral ischemia in piglets.
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cardiopulmonary Bypass; Cerebrovascular Circulation; Glucose; Hypotension; Lactic Acid; Microdialysis; Nitroprusside; Norepinephrine; Pyruvic Acid; Swine; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Coronary Circulation; Glucose; Glycerol; Heart Rate; Hemodynamics; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Pyruvic Acid; Sus scrofa | 2006 |
The effect of paracrine/autocrine interactions on the in vitro culture of bovine preimplantation embryos.
Topics: Animals; Blastocyst; Cattle; Cell Communication; Embryo Culture Techniques; Embryonic Development; Fluorometry; Glucose; Lactic Acid; Platelet Activating Factor; Pyruvic Acid; Signal Transduction; Zygote | 2006 |
Glucose metabolism in rat retinal pigment epithelium.
Topics: Animals; Carbon Dioxide; Diabetes Mellitus, Experimental; Female; Glucose; Glycogen; Lactic Acid; Pigment Epithelium of Eye; Pyruvic Acid; Rats; Rats, Long-Evans | 2006 |
Respiratory chain deficiency in a female with Aicardi-Goutières syndrome.
Topics: Basal Ganglia; Calcinosis; Chromatography, Gas; Dementia, Vascular; Female; Humans; Interferon-alpha; Ketone Bodies; Lactic Acid; Lymphocytosis; Magnetic Resonance Imaging; Mitochondrial Diseases; Muscle, Skeletal; Psychomotor Disorders; Pyruvic Acid; Seizures; Syndrome | 2006 |
Microdialysis in clinical practice: monitoring intraoral free flaps.
Topics: Adult; Blood Glucose; Female; Humans; Ischemia; Lactic Acid; Male; Microdialysis; Mouth Neoplasms; Postoperative Care; Postoperative Complications; Practice Patterns, Physicians'; Pyruvic Acid; Surgical Flaps | 2006 |
24-h storage of pig livers in UW, HTK, hydroxyethyl starch, and saline solution: is microdialysis an appropriate method for the continuous graft monitoring during preservation?
Topics: Adenosine; Allopurinol; Animals; Aspartate Aminotransferases; Cold Temperature; Glucose; Glutathione; Glycerol; Hydroxyethyl Starch Derivatives; In Vitro Techniques; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; Mannitol; Microdialysis; Monitoring, Physiologic; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Procaine; Pyruvic Acid; Raffinose; Sodium Chloride; Sus scrofa | 2006 |
Differential metabolic adaptation to acute and long-term hypoxia in rat primary cortical astrocytes.
Topics: Adaptation, Physiological; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cell Hypoxia; Cell Size; Cell Survival; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Glial Fibrillary Acidic Protein; Glucose; Immunohistochemistry; Lactic Acid; Phosphorylation; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tritium | 2006 |
Real-time nucleic acid sequence-based amplification assay to quantify changes in mitochondrial DNA concentrations in cell cultures and blood cells from HIV-infected patients receiving antiviral therapy.
Topics: Anti-HIV Agents; Base Sequence; Blood Platelets; Cell Nucleus; Cells, Cultured; Didanosine; DNA, Mitochondrial; Drug Therapy, Combination; Feasibility Studies; Fibroblasts; HIV Infections; Humans; Indinavir; Lactic Acid; Lamivudine; Leukocytes, Mononuclear; Nucleic Acid Amplification Techniques; Pyruvic Acid; Stavudine; Zalcitabine | 2006 |
Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation.
Topics: Animals; Diaphragm; Fatty Acids; Glucose; Glycolysis; Homeostasis; Insulin; Isoenzymes; Lactic Acid; Liver; Male; Mice; Mice, Knockout; Organ Specificity; Oxidation-Reduction; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Starvation; Up-Regulation | 2006 |
Fermentation metabolism in roots of wheat seedlings after hypoxic pre-treatment in different anoxic incubation systems.
Topics: Acclimatization; Adenosine Triphosphate; Disasters; Ethanol; Fermentation; Glycolysis; Kinetics; Lactic Acid; Oxygen; Plant Roots; Pyruvic Acid; Seedlings; Triticum | 2007 |
Desulfovibrio alkalitolerans sp. nov., a novel alkalitolerant, sulphate-reducing bacterium isolated from district heating water.
Topics: Acetic Acid; Alkalies; Anti-Bacterial Agents; Base Composition; Denmark; Desulfovibrio; DNA, Bacterial; DNA, Ribosomal; Formates; Genes, rRNA; Hydrogen; Hydrogen-Ion Concentration; Lactic Acid; Molecular Sequence Data; Movement; Oxidation-Reduction; Phylogeny; Pyruvic Acid; RNA, Bacterial; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sulfates; Sulfites; Temperature; Water Microbiology | 2006 |
Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo.
Topics: Amino Acids; Animals; Biological Transport; Blood Glucose; Carbon; Fatty Acids; Gene Expression Regulation, Fungal; Genes, Fungal; Lactic Acid; Male; Mice; Mycoses; Nitrogen; Polyamines; Pyruvic Acid; Quaternary Ammonium Compounds; Saccharomyces cerevisiae; Trehalose; Urea | 2006 |
DPCPX-resistant hypoxic synaptic depression in the CA1 region of hippocampal slices: possible role of intracellular accumulation of monocarboxylates.
Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Anaerobiosis; Animals; Excitatory Postsynaptic Potentials; Glucose; Glycolysis; Hippocampus; In Vitro Techniques; Lactic Acid; Male; Oxygen; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Xanthines | 2006 |
Reexamining the hyperglycemic pseudohypoxia hypothesis of diabetic oculopathy.
Topics: Adenosine Triphosphate; Aldehyde Reductase; Animals; Cell Culture Techniques; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Epithelial Cells; Glucose; Humans; Hyperglycemia; Hypoxia; Lactic Acid; Lens, Crystalline; NAD; Pigment Epithelium of Eye; Pyruvic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Retina | 2006 |
Insulin-stimulated NADH/NAD+ redox state increases NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cell Movement; Cells, Cultured; Drug Synergism; Enzyme Activation; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Muscle, Smooth, Vascular; NAD; NADPH Oxidases; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2006 |
Resuscitation of severe but brief haemorrhagic shock with PFC in rabbits restores skeletal muscle oxygen delivery and does not alter skeletal muscle metabolism.
Topics: Animals; Blood Pressure; Blood Substitutes; Disease Models, Animal; Fluorocarbons; Hyperoxia; Lactic Acid; Linear Models; Male; Microcirculation; Muscle, Skeletal; Oxygen; Pyruvic Acid; Rabbits; Resuscitation; Shock, Hemorrhagic | 2006 |
Changes in diffusion parameters, energy-related metabolites and glutamate in the rat cortex after transient hypoxia/ischemia.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Energy Metabolism; Extracellular Space; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Kinetics; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Wistar | 2006 |
Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media.
Topics: Amino Acids; Ammonia; Animals; Bioreactors; Cell Count; Cell Culture Techniques; Cell Line; Culture Media, Serum-Free; Dogs; Glucose; Hemagglutinins; Hydrogen-Ion Concentration; Influenza A Virus, H3N8 Subtype; Lactic Acid; Pyruvic Acid; Time Factors | 2006 |
Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Female; Galactose; Glucose; Glutamine; Glyceraldehyde; Islets of Langerhans; Keto Acids; Lactic Acid; Leucine; Mannose; Nutritional Physiological Phenomena; Pyruvic Acid; Rats; Rats, Wistar | 2006 |
MCA Vmean and the arterial lactate-to-pyruvate ratio correlate during rhythmic handgrip.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Brain; Cerebrovascular Circulation; Exercise; Glucose Clamp Technique; Hand Strength; Heart Rate; Humans; Hyperglycemia; Lactic Acid; Male; Middle Cerebral Artery; Pyruvic Acid; Ultrasonography, Doppler, Transcranial | 2006 |
Evaluation of myocardial metabolism with microdialysis after protection with cold blood- or cold crystalloid cardioplegia. A porcine model.
Topics: Animals; Cardioplegic Solutions; Female; Glycerol; Heart; Heart Arrest, Induced; Hypothermia, Induced; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardium; Oxidation-Reduction; Pyruvic Acid; Swine | 2006 |
Quantitation of ischemic events after severe traumatic brain injury in humans: a simple scoring system.
Topics: Adult; Age Factors; Brain Chemistry; Brain Injuries; Brain Ischemia; Extracellular Fluid; Female; Glasgow Outcome Scale; Glucose; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Neurologic Examination; Oxygen Consumption; Pyruvic Acid; Retrospective Studies; Treatment Outcome | 2006 |
Energy metabolism and biotransformation as endpoints to pre-screen hepatotoxicity using a liver spheroid model.
Topics: Animals; Biotransformation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endpoint Determination; Energy Metabolism; Glucose; Hepatocytes; Lactic Acid; Male; Pyruvic Acid; Rats; Rats, Wistar; Spheroids, Cellular; Toxicity Tests; Xenobiotics | 2006 |
Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy.
Topics: Animals; Cardiotonic Agents; Citric Acid Cycle; Fatty Acids; Heart; Isoproterenol; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Mice; Organ Culture Techniques; Oxidation-Reduction; Perfusion; Pyruvic Acid; Triglycerides | 2006 |
Effectiveness of extracellular lactate/pyruvate for sustaining synaptic vesicle proton gradient generation and vesicular accumulation of GABA.
Topics: Adenosine Triphosphate; Animals; Carboxylic Acids; Dose-Response Relationship, Drug; Energy Metabolism; Extracellular Space; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Membrane Potentials; Neurotransmitter Agents; Pyruvic Acid; Rats; Rats, Wistar; Synaptic Vesicles; Synaptosomes | 2006 |
Decreasing gut wall glucose as an early marker of impaired intestinal perfusion.
Topics: Animals; Balloon Occlusion; Biomarkers; Carbon Dioxide; Duodenum; Glucose; Intestinal Mucosa; Jejunum; Lactic Acid; Laser-Doppler Flowmetry; Mesenteric Artery, Superior; Mesentery; Microcirculation; Muscle, Smooth, Vascular; Oxygen Consumption; Portal Vein; Prospective Studies; Pyruvic Acid; Regional Blood Flow; Swine | 2006 |
Metabolic effects of l-alanyl-glutamine in burned rats.
Topics: Animals; Blood Glucose; Burns; Dipeptides; Ketone Bodies; Lactic Acid; Male; Muscle, Skeletal; Pyruvic Acid; Rats; Rats, Wistar; Skin | 2006 |
Fructose-1,6-bisphosphate supports cerebral energy metabolism in pigs after ischemic brain injury caused by experimental particle embolization.
Topics: Animals; Brain; Brain Ischemia; Circulatory Arrest, Deep Hypothermia Induced; Disease Models, Animal; Energy Metabolism; Fructosediphosphates; Intracranial Embolism; Lactic Acid; Neuroprotective Agents; Pyruvic Acid; Swine | 2006 |
Pyruvate metabolism in working human skeletal muscle.
Topics: Exercise; Glycogenolysis; Humans; Hyperoxia; Lactic Acid; Muscle, Skeletal; Pyruvic Acid | 2007 |
High dietary sucrose triggers hyperinsulinemia, increases myocardial beta-oxidation, reduces glycolytic flux and delays post-ischemic contractile recovery.
Topics: Animals; Blood Glucose; Body Weight; Dietary Sucrose; Glycolysis; Hyperinsulinism; In Vitro Techniques; Insulin; Lactic Acid; Lipids; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organ Size; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar; Triglycerides | 2007 |
Brain metabolism and extracellular space diffusion parameters during and after transient global hypoxia in the rat cortex.
Topics: Animals; Cerebral Cortex; Diffusion; Disease Models, Animal; Down-Regulation; Energy Metabolism; Extracellular Space; Glucose; Glutamic Acid; Hypoxia, Brain; Lactic Acid; Male; Microdialysis; Neuroglia; Neurons; Pyruvic Acid; Rats; Rats, Wistar; Recovery of Function; Up-Regulation | 2007 |
Activin a release into cerebrospinal fluid in a subset of patients with severe traumatic brain injury.
Topics: Activins; Adolescent; Adult; Aged; Brain Injuries; Case-Control Studies; Female; Follistatin; Glutamic Acid; Glycerol; Humans; Lactic Acid; Male; Middle Aged; Nerve Growth Factors; Phosphopyruvate Hydratase; Pyruvic Acid; Radiography; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Trauma Severity Indices | 2006 |
Glucose metabolites in the striatum of freely behaving rats following infusion of elevated potassium.
Topics: Animals; Glucose; Lactic Acid; Male; Microdialysis; Neostriatum; Potassium; Pyruvic Acid; Rats; Rats, Inbred F344 | 2006 |
Improved metabolic stimulus for glucose-induced insulin secretion through GK and PFK-2/FBPase-2 coexpression in insulin-producing RINm5F cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Cell Survival; Glucokinase; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Lactic Acid; Metabolic Networks and Pathways; Phosphofructokinase-2; Protein Binding; Pyruvic Acid; Rats; Transfection | 2006 |
Intraperitoneal microdialysis: Postoperative monitoring of splanchnic ischemia by measurements of the lactate pyruvate ratio.
Topics: Aged; Aged, 80 and over; Female; Humans; Ischemia; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Peritoneum; Postoperative Complications; Pyruvic Acid; Splanchnic Circulation | 2006 |
Inducible and neuronal nitric oxide synthases (NOS) have complementary roles in recovery sleep induction.
Topics: Adenosine; Animals; Arginine; Electroencephalography; Electromyography; Imines; Lactic Acid; Lipopolysaccharides; Male; Microinjections; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pyruvic Acid; Rats; Rats, Wistar; Sleep Deprivation; Sleep Stages; Wakefulness | 2006 |
Towards industrial application of quasi real-time metabolic flux analysis for mammalian cell culture.
Topics: Animals; Bioreactors; Biotechnology; Cell Culture Techniques; CHO Cells; Citrate (si)-Synthase; Citric Acid Cycle; Cricetinae; Cricetulus; Glucose; Glutamine; Ketone Oxidoreductases; Lactic Acid; Models, Biological; Pyruvate Kinase; Pyruvic Acid; Signal Transduction | 2006 |
Elevated lactate suppresses neuronal firing in vivo and inhibits glucose metabolism in hippocampal slice cultures.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Energy Metabolism; Glucose; Hippocampus; Lactic Acid; Male; NAD; Neurons; Organ Culture Techniques; Oxidation-Reduction; Oxidative Phosphorylation; Pyramidal Cells; Pyruvic Acid; Rats; Rats, Long-Evans; Synaptic Transmission; Up-Regulation | 2006 |
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.
Topics: Adenine Nucleotides; Adenosine; Androstadienes; Animals; Cells, Cultured; Cerebral Cortex; Chromones; Flavonoids; Glucose; Insulin; Lactic Acid; Morpholines; Neurons; Oxidative Stress; Phosphocreatine; Pyruvic Acid; Rats; Rats, Wistar; Thioinosine; Wortmannin | 2006 |
High resolution 1H NMR investigations of the oxidative consumption of salivary biomolecules by ozone: relevance to the therapeutic applications of this agent in clinical dentistry.
Topics: Carbohydrates; Dentistry; Female; Free Radicals; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Methionine; Oxidation-Reduction; Ozone; Pyruvic Acid; Saliva; Uric Acid | 2006 |
Nitric oxide production in the basal forebrain is required for recovery sleep.
Topics: Adenosine; Animals; Diagonal Band of Broca; Energy Metabolism; Enzyme Inhibitors; Free Radical Scavengers; Lactic Acid; Male; Microdialysis; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Prosencephalon; Pyruvic Acid; Rats; Rats, Wistar; Recovery of Function; Signal Transduction; Sleep; Sleep Deprivation; Up-Regulation | 2006 |
Sustained generation of electricity by the spore-forming, Gram-positive, Desulfitobacterium hafniense strain DCB2.
Topics: Anthraquinones; Bioelectric Energy Sources; Desulfitobacterium; Electricity; Electrodes; Ethanol; Formates; Hydrogen; Lactic Acid; Microscopy, Electron, Scanning; Oxidation-Reduction; Pyruvic Acid; Time Factors | 2007 |
Lactic acid, pyruvic acid and lactate/pyruvate ratio in the Anoplocephalid tapeworm Stilesia globipunctata infecting sheep (Ovis aries).
Topics: Anaerobiosis; Animals; Cestoda; Cestode Infections; Energy Metabolism; Host-Parasite Interactions; Lactic Acid; Pyruvic Acid; Sheep; Sheep Diseases; Species Specificity | 2007 |
Levosimendan cardioprotection reduces the metabolic response during temporary regional coronary occlusion in an open chest pig model.
Topics: Animals; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Glucose; Hydrazones; Infusions, Intravenous; Lactic Acid; Microdialysis; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Pyridazines; Pyruvic Acid; Simendan; Sus scrofa | 2007 |
Low doses of tumour necrosis factor alpha and interleukin 1beta diminish hepatic gluconeogenesis from alanine in vivo.
Topics: Alanine; Ammonia; Animals; Dose-Response Relationship, Drug; Drug Combinations; Gluconeogenesis; Glucose; Infusions, Intravenous; Interleukin-1beta; Lactic Acid; Liver; Male; Oxygen Consumption; Perfusion; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha; Urea | 2006 |
Desulfotomaculum thermosubterraneum sp. nov., a thermophilic sulfate-reducer isolated from an underground mine located in a geothermally active area.
Topics: Alanine; Alcohols; Bacterial Typing Techniques; Base Composition; Carbohydrate Metabolism; Carboxylic Acids; Desulfotomaculum; DNA, Bacterial; DNA, Ribosomal; Fatty Acids; Genes, rRNA; Growth Inhibitors; Hydrogen; Hydrogen-Ion Concentration; Japan; Lactic Acid; Mining; Molecular Sequence Data; Movement; Nucleic Acid Hybridization; Phylogeny; Pyruvic Acid; Quinones; RNA, Bacterial; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Sodium Chloride; Soil Microbiology; Sulfates; Sulfites; Sulfur; Temperature | 2006 |
Pseudomonas stutzeri as a novel biocatalyst for pyruvate production from DL-lactate.
Topics: Biotransformation; Lactic Acid; Pseudomonas stutzeri; Pyruvic Acid | 2007 |
Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis.
Topics: Alanine; Animals; Carbon Isotopes; Lactic Acid; Magnetic Resonance Imaging; Male; Neoplasms, Experimental; Pyruvic Acid; Rats | 2006 |
Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction.
Topics: Blood Pressure; Brain; Brain Edema; Cerebrovascular Circulation; Disease Progression; Energy Metabolism; Female; Homeostasis; Humans; Infarction, Middle Cerebral Artery; Lactic Acid; Male; Middle Aged; Middle Cerebral Artery; Oxygen Consumption; Predictive Value of Tests; Prognosis; Pyruvic Acid; Tomography, X-Ray Computed | 2007 |
Prediction of postoperative complications after urgent laparotomy by intraperitoneal microdialysis: A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Lactic Acid; Laparotomy; Male; Microdialysis; Middle Aged; Peritoneal Dialysis; Pilot Projects; Predictive Value of Tests; Pyruvic Acid | 2006 |
Brief report: High frequency of biochemical markers for mitochondrial dysfunction in autism: no association with the mitochondrial aspartate/glutamate carrier SLC25A12 gene.
Topics: Aspartic Acid; Autistic Disorder; Chromosome Mapping; DNA Mutational Analysis; DNA Primers; DNA, Mitochondrial; Gene Expression; Gene Frequency; Glutamic Acid; Haplotypes; Humans; Lactic Acid; Membrane Transport Proteins; Mitochondrial Diseases; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Pyruvic Acid | 2006 |
Microdialysis shows metabolic effects in skin during fluid resuscitation in burn-injured patients.
Topics: Acidosis; Adolescent; Adult; Blood Glucose; Burns; Female; Fluid Therapy; Humans; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Skin | 2006 |
A bioluminescence technique for quantitative and structure-associated imaging of pyruvate.
Topics: Biological Assay; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Diagnostic Imaging; Frozen Sections; Glycolysis; Head and Neck Neoplasms; Humans; Lactic Acid; Luminescent Measurements; Luminescent Proteins; Muscles; Muscular Diseases; Neoplasms, Squamous Cell; Oxidation-Reduction; Pyruvic Acid | 2007 |
A theoretical analysis of rate constants and kinetic isotope effects corresponding to different reactant valleys in lactate dehydrogenase.
Topics: Catalysis; Computer Simulation; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Biological; Models, Molecular; Protein Conformation; Protons; Pyruvic Acid; Thermodynamics; Time Factors; Water | 2006 |
Regulation of redox metabolism in the mouse oocyte and embryo.
Topics: Animals; Cytosol; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Flavin-Adenine Dinucleotide; Glucose; Glutathione; In Vitro Techniques; Lactic Acid; Mice; Microscopy, Confocal; Mitochondria; Models, Biological; NAD; NADP; Oocytes; Oxidation-Reduction; Pregnancy; Pyruvic Acid | 2007 |
Functional analysis of Kluyveromyces lactis carboxylic acids permeases: heterologous expression of KlJEN1 and KlJEN2 genes.
Topics: Carboxylic Acids; Dicarboxylic Acid Transporters; Gene Expression Regulation, Fungal; Kluyveromyces; Lactic Acid; Membrane Transport Proteins; Monocarboxylic Acid Transporters; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Sequence Homology, Nucleic Acid; Symporters | 2007 |
Lactate and ethanol productions by Rhizopus oryzae ATCC 9363 and activities of related pyruvate branch point enzymes.
Topics: Biomass; Ethanol; Fermentation; L-Lactate Dehydrogenase; Lactic Acid; Pyruvic Acid; Rhizopus | 2006 |
[Monitoring free flaps with cutaneous microdialysis: preliminary study in oral cavity reconstruction].
Topics: Blood Glucose; Feasibility Studies; Humans; Ischemia; Lactic Acid; Microdialysis; Microsurgery; Monitoring, Physiologic; Mouth Floor; Mouth Neoplasms; Oral Surgical Procedures; Plastic Surgery Procedures; Postoperative Care; Pyruvic Acid; Surgical Flaps | 2006 |
Metabolic and ionoregulatory responses of the Amazonian cichlid, Astronotus ocellatus, to severe hypoxia.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Blood Glucose; Cichlids; Creatine; Erythrocyte Indices; Gills; Glycogen; Hematocrit; Hemoglobins; Hydrogen-Ion Concentration; Hypoxia; Ions; Kidney; L-Lactate Dehydrogenase; Lactic Acid; Liver; Muscle Fibers, Fast-Twitch; Oxygen; Phosphocreatine; Pyruvate Dehydrogenase Complex; Pyruvic Acid; RNA, Messenger; Sodium-Potassium-Exchanging ATPase | 2007 |
Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients.
Topics: Astrocytes; Brain; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Male; Microdialysis; Neurons; Pyruvic Acid; Subarachnoid Hemorrhage | 2007 |
Microdialysis to monitor scalp flap viability.
Topics: Graft Survival; Humans; Lactic Acid; Microdialysis; Postoperative Complications; Pyruvic Acid; Scalp; Surgical Flaps; Tissue Survival | 2007 |
Comparison of plasma metabolite concentrations and peripheral leukocyte enzyme activities in sheep fed on different diets in New Zealand and Japan.
Topics: Animal Feed; Animals; Blood Glucose; Blood Proteins; Cholesterol; Diet; Female; Insulin; Japan; L-Lactate Dehydrogenase; Lactic Acid; Leukocytes, Mononuclear; Malate Dehydrogenase; New Zealand; Pregnancy; Pyruvic Acid; Sheep; Triglycerides | 2007 |
Tracheostomy tape: more trouble than it's worth?
Topics: Aged; Female; Humans; Ischemia; Lactic Acid; Microdialysis; Mouth Neoplasms; Pyruvic Acid; Surgical Flaps; Tracheostomy | 2007 |
Is it worthwhile to use cerebral microdialysis in patients with acute liver failure?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Brain; Brain Edema; Critical Care; Extracellular Fluid; Hepatic Encephalopathy; Humans; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Microdialysis; Monitoring, Physiologic; Pyruvic Acid | 2006 |
Microdialysis in the management of hepatic encephalopathy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Blood Glucose; Brain; Brain Edema; Critical Care; Dextropropoxyphene; Drug Combinations; Drug Interactions; Extracellular Fluid; Female; Frontal Lobe; Glucose; Hepatic Encephalopathy; Humans; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Microdialysis; Middle Aged; Pyruvic Acid; Risperidone | 2006 |
Pericontusional brain tissue exhibits persistent elevation of lactate/pyruvate ratio independent of cerebral perfusion pressure.
Topics: Adolescent; Adult; Biomarkers; Brain; Brain Injuries; Cerebrovascular Circulation; Female; Glasgow Coma Scale; Hospitals, University; Humans; Intensive Care Units; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Retrospective Studies | 2007 |
Efficiency of trekrezan in experimental bronchopneumonia in rats.
Topics: Acetates; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Bronchopneumonia; Drug Combinations; Energy Metabolism; Ethanolamines; Lactic Acid; Lung; Lymphocytes; Pyruvic Acid; Rats | 2006 |
Synthes Award For Resident Research On Craniofacial And Brain Injury: effect of cyclosporin A, topiramate, or 100% oxygen as proposed "neuroprotective" therapies on the neurochemical analytes in patients with severe traumatic brain injury.
Topics: Adult; Awards and Prizes; Brain Injuries; Case-Control Studies; Cohort Studies; Cyclosporine; Fructose; Glucose; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Neuroprotective Agents; Oxygen Inhalation Therapy; Pyruvic Acid; Topiramate | 2006 |
Diagnostic accuracy of blood lactate-to-pyruvate molar ratio in the differential diagnosis of congenital lactic acidosis.
Topics: Acidosis, Lactic; Child; Diagnosis, Differential; Female; Hospitals, Pediatric; Humans; Lactic Acid; Male; Mitochondrial Diseases; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid; Retrospective Studies; ROC Curve; Sensitivity and Specificity | 2007 |
Sleeping Beauty: a tale still with an uncertain happy ending after head trauma.
Topics: Biomarkers; Brain; Brain Injuries; Cerebrovascular Circulation; Glasgow Coma Scale; Hospitals, University; Humans; Intensive Care Units; Intracranial Pressure; Lactic Acid; Microdialysis; Pyruvic Acid | 2007 |
Mass isotopomer study of anaplerosis from propionate in the perfused rat heart.
Topics: Acyl Coenzyme A; Animals; Carbon Isotopes; Citric Acid Cycle; Deuterium; Glucose; In Vitro Techniques; Lactic Acid; Male; Myocardium; Perfusion; Propionates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2007 |
Effect of pH on the development of acrosomal responsiveness of human sperm.
Topics: Acrosome Reaction; Cholesterol; Extracellular Space; Humans; Hydrogen-Ion Concentration; Intracellular Space; Lactic Acid; Male; Pyruvic Acid; Spermatozoa | 2007 |
Hypertonic 15% sodium pyruvate offers no initial resuscitation advantage compared with 8% hypertonic NACl in sheep with multiple hemorrhages.
Topics: Animals; Blood Pressure; Female; Fluid Therapy; Hypertonic Solutions; Lactic Acid; Plasma Volume; Pyruvic Acid; Resuscitation; Saline Solution, Hypertonic; Sheep; Shock, Hemorrhagic; Time Factors; Treatment Outcome | 2007 |
A glycogen phosphorylase inhibitor selectively enhances local rates of glucose utilization in brain during sensory stimulation of conscious rats: implications for glycogen turnover.
Topics: Acoustic Stimulation; Afferent Pathways; Animals; Blood Glucose; Brain; Carbon Radioisotopes; Citric Acid Cycle; Consciousness; Energy Metabolism; Enzyme Inhibitors; Glucose; Glycogen; Glycogen Phosphorylase, Brain Form; Lactic Acid; Male; Photic Stimulation; Physical Stimulation; Pyruvic Acid; Rats; Rats, Wistar; Sensation; Up-Regulation | 2007 |
Measurement of the ratio of lactate to pyruvate in skin fibroblast cultures.
Topics: Cells, Cultured; Clinical Laboratory Techniques; Fibroblasts; Humans; L-Lactate Dehydrogenase; Lactic Acid; Models, Biological; Pyruvic Acid; Skin | 2007 |
Analysis of the myocardial metabolism by microdialysis during open beating heart surgery.
Topics: Aged; Cardiac Catheterization; Cardiovascular Diseases; Coronary Artery Bypass, Off-Pump; Female; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Myocardial Revascularization; Myocardium; Pyruvic Acid; Retrospective Studies; Time Factors | 2007 |
Biochemical alterations in the trapezius muscle of patients with chronic whiplash associated disorders (WAD)--a microdialysis study.
Topics: Adult; Chronic Disease; Exercise; Female; Glutamic Acid; Humans; Interleukin-6; Lactic Acid; Microdialysis; Middle Aged; Muscle, Skeletal; Neck Pain; Pain Measurement; Pain Threshold; Potassium; Pressure; Pyruvic Acid; Regional Blood Flow; Serotonin; Shoulder; Whiplash Injuries | 2008 |
Anaerobic degradation of nonylphenol in soil.
Topics: Acetates; Anaerobiosis; Bacteria, Anaerobic; Biodegradation, Environmental; Half-Life; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Phenols; Pyruvic Acid; Soil Microbiology; Soil Pollutants; Temperature | 2007 |
[Dilated cardiomyopathy, diabetes and deafness related to a mutation of mitochondrial DNA].
Topics: Cardiomyopathy, Dilated; Deafness; Diabetes Mellitus; DNA, Mitochondrial; Female; Humans; Lactic Acid; Middle Aged; Mutation; Pyruvic Acid; Syndrome | 2007 |
Quantification of 13C pyruvate and 13C lactate in dog blood by reversed-phase liquid chromatography-electrospray ionization mass spectrometry after derivatization with 3-nitrophenylhydrazine.
Topics: Animals; Carbon Isotopes; Chromatography, Liquid; Dogs; Indicators and Reagents; Lactic Acid; Molecular Weight; Phenylhydrazines; Pyruvic Acid; Quality Control; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2007 |
Chronic hypoxia differentially increases glutathione content and gamma-glutamyl cysteine synthetase expression in fetal guinea pig organs.
Topics: Animals; Blotting, Western; Body Weight; Female; Fetal Hypoxia; Fetus; Glutamate-Cysteine Ligase; Glutathione; Guinea Pigs; Immunohistochemistry; Kidney; Lactic Acid; Liver; Lung; Organ Size; Pregnancy; Pyruvic Acid | 2008 |
Metabolic characterization of Escherichia coli strains adapted to growth on lactate.
Topics: Acetyl Coenzyme A; Biomass; Carbon; Carbon Isotopes; Escherichia coli; Gene Expression Regulation, Bacterial; Gluconeogenesis; Lactic Acid; Metabolic Networks and Pathways; Oxaloacetic Acid; Phosphoenolpyruvate; Pyruvic Acid; Transcription, Genetic | 2007 |
Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study.
Topics: Action Potentials; Aerobiosis; Animals; Dose-Response Relationship, Drug; Electrophysiology; Glucose; Glycolysis; Hippocampus; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Male; Malonates; Models, Biological; Neurons; Organic Chemicals; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2007 |
Metabolic engineering of Bacillus subtilis for ethanol production: lactate dehydrogenase plays a key role in fermentative metabolism.
Topics: Bacillus subtilis; Bacterial Proteins; Butylene Glycols; Ethanol; Fermentation; Gene Deletion; Genes, Bacterial; Genetic Vectors; L-Lactate Dehydrogenase; Lactic Acid; Models, Biological; Models, Genetic; NAD; NADP; Pyruvic Acid | 2007 |
Comparison of terlipressin and noradrenalin on cerebral perfusion, intracranial pressure and cerebral extracellular concentrations of lactate and pyruvate in patients with acute liver failure in need of inotropic support.
Topics: Adolescent; Adult; Brain; Cerebrovascular Circulation; Extracellular Fluid; Female; Humans; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Lypressin; Male; Microdialysis; Middle Aged; Norepinephrine; Osmolar Concentration; Pyruvic Acid; Terlipressin; Treatment Outcome; Vasoconstrictor Agents | 2007 |
Kinetic properties of the redox switch/redox coupling mechanism as determined in primary cultures of cortical neurons and astrocytes from rat brain.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Energy Metabolism; Glucose; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Neurons; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar | 2007 |
Evaluating tissue perfusion using labelled water indicator microdialysis in a rat model of haemorrhagic shock.
Topics: Animals; Blood Pressure; Disease Models, Animal; Lactic Acid; Liver; Male; Microdialysis; Muscle, Skeletal; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Shock, Hemorrhagic; Time Factors; Water | 2007 |
Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model.
Topics: Animals; Body Weight; Bread; Cerebellum; Diet; Disease Models, Animal; Glucose; Glutamic Acid; Kidney; Lactic Acid; Liver; Pyruvic Acid; Rats; Rats, Wistar; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Triticum | 2007 |
L-arginine causes amelioration of cerebrovascular dysfunction and brain inflammation during experimental heatstroke.
Topics: Animals; Arginine; Cerebrovascular Circulation; Cerebrovascular Disorders; Cytokines; Encephalitis; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Glycerol; Heat Stroke; Hypothalamus; Interleukin-10; Interleukin-1beta; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Nitric Oxide; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2008 |
Microdialysis monitoring for evaluation of the influence exerted by pneumoperitoneum on the kidney: an experimental study.
Topics: Animals; Area Under Curve; Glucose; Glycerol; Kidney; Lactic Acid; Laparoscopy; Microdialysis; Nephrectomy; Pneumoperitoneum, Artificial; Pyruvic Acid; Statistics, Nonparametric; Swine | 2008 |
The highly toxic oxyanion tellurite (TeO (3) (2-) ) enters the phototrophic bacterium Rhodobacter capsulatus via an as yet uncharacterized monocarboxylate transport system.
Topics: Acetic Acid; Biological Transport, Active; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Enzyme Inhibitors; Lactic Acid; Malates; Monocarboxylic Acid Transporters; Potassium Cyanide; Pyruvic Acid; Rhodobacter capsulatus; Succinic Acid; Tellurium | 2008 |
Association between intracranial pulse pressure levels and brain energy metabolism in a patient with an aneurysmal subarachnoid haemorrhage.
Topics: Aged; Brain; Brain Ischemia; Female; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Intracranial Pressure; Lactic Acid; Microdialysis; Pyruvic Acid; Subarachnoid Hemorrhage | 2007 |
Deep sedation with dexmedetomidine in a porcine model does not compromise the viability of free microvascular flap as depicted by microdialysis and tissue oxygen tension.
Topics: Animals; Blood Pressure; Cardiac Output; Cell Survival; Central Venous Pressure; Consciousness; Dexmedetomidine; Female; Glucose; Hypnotics and Sedatives; Lactic Acid; Microcirculation; Microdialysis; Models, Animal; Oxygen; Partial Pressure; Propofol; Pyruvic Acid; Rectus Abdominis; Surgical Flaps; Sus scrofa; Sympathectomy; Time Factors; Vascular Resistance | 2007 |
Brain metabolism during a decrease in cerebral perfusion pressure caused by an elevated intracranial pressure in the porcine neocortex.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Glucose; Glutamic Acid; Glycerol; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Neocortex; Pyruvic Acid; Sus scrofa; Time Factors | 2007 |
Therapeutic potential of pyruvate therapy for mitochondrial diseases.
Topics: Adult; Animals; Calcium-Binding Proteins; Enzyme Activation; Ethanol; Female; Glycolysis; Humans; Lactic Acid; Mice; Mitochondrial Diseases; Organic Anion Transporters; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid | 2007 |
Intramuscular injection of sevoflurane detects malignant hyperthermia predisposition in susceptible pigs.
Topics: Anesthetics, Inhalation; Animals; Blood Glucose; Carbon Dioxide; Dantrolene; Dose-Response Relationship, Drug; Hypertension, Malignant; Injections, Intramuscular; Lactic Acid; Methyl Ethers; Microdialysis; Muscle Relaxants, Central; Pyruvic Acid; Sevoflurane; Swine | 2007 |
Least-squares chemical shift separation for (13)C metabolic imaging.
Topics: Alanine; Algorithms; Carbon Isotopes; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lactic Acid; Least-Squares Analysis; Magnetic Resonance Imaging; Models, Biological; Models, Chemical; Models, Statistical; Phantoms, Imaging; Pyruvic Acid | 2007 |
Different effects of monocarboxylates on neuronal survival and beta-amyloid toxicity.
Topics: Aconitate Hydratase; Adenosine Triphosphate; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Cell Survival; Drug Interactions; Glucose; Hippocampus; Lactic Acid; NAD; Neurons; Organ Culture Techniques; Pyruvic Acid; Rats; Rats, Wistar; Time Factors | 2007 |
A computer model of gluconeogenesis and lipid metabolism in the perfused liver.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Algorithms; Animals; Catalysis; Citric Acid Cycle; Computer Simulation; Enzymes; Fatty Acids; Gluconeogenesis; Glucose; Glycolysis; Ketones; Kinetics; Lactic Acid; Lipid Metabolism; Liver; Models, Biological; Oxidative Phosphorylation; Perfusion; Pyruvic Acid; Rats; Tricarboxylic Acids | 2007 |
Energy substrates in bovine oviduct and uterine fluid and blood plasma during the oestrous cycle.
Topics: Animals; Blood Glucose; Body Fluids; Cattle; Energy Metabolism; Estrous Cycle; Female; Glucose; Lactic Acid; Osmolar Concentration; Oviducts; Pyruvic Acid; Time Factors; Uterus | 2008 |
The control of hepatic glycogen metabolism in an in vitro model of sepsis.
Topics: Adenylate Kinase; Animals; Cytokines; Disease Models, Animal; Glucose; Glucose-6-Phosphate; Glycogen Phosphorylase; Glycogen Synthase; Glycogen Synthase Kinase 3; Glycogenolysis; Humans; Lactic Acid; Lipopolysaccharides; Liver; Liver Glycogen; Male; omega-N-Methylarginine; Phosphorylation; Protein Kinases; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sepsis; Uridine Diphosphate Glucose | 2008 |
Posttraumatic brain vulnerability to hypoxia-hypotension: the importance of the delay between brain trauma and secondary insult.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Disease Models, Animal; Glucose; Glycerol; Hypoxia, Brain; Intracranial Hypotension; Lactic Acid; Male; Oxygen; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carbon Isotopes; Cell Death; Cell Line, Tumor; Etoposide; Lactate Dehydrogenases; Lactic Acid; Lymphoma; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Neoplasm Transplantation; Pyruvic Acid | 2007 |
Metabolic response in microvascular flaps during partial pedicle obstruction and hypovolemic shock.
Topics: Animals; Female; Glucose; Graft Occlusion, Vascular; Lactic Acid; Microdialysis; Models, Biological; Pyruvic Acid; Rectus Abdominis; Regional Blood Flow; Shock; Skin; Surgical Flaps; Swine | 2007 |
Chlorogenic acid reduces the plasma glucose peak in the oral glucose tolerance test: effects on hepatic glucose release and glycaemia.
Topics: Animals; Area Under Curve; Blood Glucose; Chlorogenic Acid; Glucose; Glucose Tolerance Test; Glucose-6-Phosphatase; Glycerol; Hydrogen-Ion Concentration; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2008 |
Functional recovery of chronic ischemic myocardium after surgical revascularization correlates with magnitude of oxidative metabolism.
Topics: Coronary Artery Bypass; Coronary Circulation; Ethanol; Glucose; Humans; Lactic Acid; Magnetic Resonance Imaging; Microdialysis; Myocardial Contraction; Myocardial Ischemia; Myocardium; Pyruvic Acid; Recovery of Function; Stroke Volume; Ventricular Function, Left | 2008 |
Inhibition of astrocytic energy metabolism by D-lactate exposure impairs memory.
Topics: Acetic Acid; Animals; Astrocytes; Brain; Chickens; Citric Acid Cycle; Energy Metabolism; Glutamic Acid; Isomerism; Lactic Acid; Male; Memory; Memory Disorders; Mitochondria; Neurons; Pyruvic Acid | 2008 |
Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis.
Topics: Case-Control Studies; Electroencephalography; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Post-Traumatic; Humans; Intracranial Hypertension; Lactic Acid; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid; Retrospective Studies; Status Epilepticus | 2007 |
Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.
Topics: Aging; Animals; Blotting, Western; Calcineurin; Cardiomyopathies; Humans; Lactic Acid; Mice; Mice, Transgenic; Myocardium; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Ultrasonography | 2008 |
Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings.
Topics: Adolescent; Adult; Brain Injuries; Cerebrum; Female; Humans; Hyperoxia; Intracranial Pressure; Lactic Acid; Male; Middle Aged; Oxygen; Prospective Studies; Pyruvic Acid | 2008 |
Normal and seizure levels of lactate, pyruvate and acid-soluble phosphates in the cerebellum and cerebrum.
Topics: Brain Chemistry; Cerebellum; Cerebrum; Humans; Lactic Acid; Phosphates; Pyruvic Acid; Seizures; Telencephalon | 1949 |
Lactate, pyruvate, and acid-soluble phosphates in monkey brains treated with carbon dioxide and electric shock.
Topics: Animals; Brain; Brain Chemistry; Carbon Dioxide; Convulsive Therapy; Haplorhini; Humans; Lactates; Lactic Acid; Phosphates; Pyruvates; Pyruvic Acid; Shock; Therapeutics | 1949 |
Effect of carbon dioxide on brain glucose, lactate, pyruvate and phosphates.
Topics: Brain; Carbon Dioxide; Glucose; Lactates; Lactic Acid; Phosphates; Pyruvates; Pyruvic Acid | 1949 |
The formation of CO2 and acetoin from pyruvate by Lactobacillus plantarum.
Topics: Acetoin; Lactic Acid; Lactobacillus; Lactobacillus plantarum; Pyruvates; Pyruvic Acid | 1949 |
Impact of hyperglycemia on neurological deficits and extracellular glucose levels in aneurysmal subarachnoid hemorrhage patients.
Topics: Adult; Blood Glucose; Brain; Energy Metabolism; Extracellular Fluid; Female; Glucose; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Male; Microdialysis; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage | 2007 |
The in vivo and in vitro effects of L-carnitine supplementation on the erythrocyte membrane acetylcholinesterase, Na+, K+-ATPase and Mg2+-ATPase activities in basketball players.
Topics: Acetylcholinesterase; Antioxidants; Basketball; Ca(2+) Mg(2+)-ATPase; Carnitine; Catecholamines; Chromatography, High Pressure Liquid; Dietary Supplements; Enzyme Activation; Erythrocyte Membrane; Humans; Lactic Acid; Male; Muscles; Pyruvic Acid; Sodium-Potassium-Exchanging ATPase; Spectrum Analysis; Time Factors | 2008 |
Neonatal pyruvate dehydrogenase deficiency due to a R302H mutation in the PDHA1 gene: MRI findings.
Topics: Brain; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Humans; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; Male; Mosaicism; Mutation; Nervous System Malformations; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid | 2008 |
A cell-based high-throughput assay system reveals modulation of oxidative and nonoxidative glucose metabolism due to commonly used organic solvents.
Topics: Adenosine Triphosphate; Biological Assay; Cell Line; Glucose; Lactic Acid; Membrane Potential, Mitochondrial; Muscle Cells; Muscle Proteins; Myoblasts; Organic Chemicals; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Reactive Oxygen Species; Solvents | 2008 |
Alterations in carbohydrate metabolism and its regulation in PPARalpha null mouse hearts.
Topics: Animals; Carbohydrate Metabolism; Carbon Isotopes; Citric Acid Cycle; Energy Metabolism; Fasting; Fatty Acids; Gene Expression Profiling; Gene Expression Regulation; Glucose; Glycogen; Glycolysis; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardium; Oxidation-Reduction; Physical Exertion; Postprandial Period; PPAR alpha; Pyruvic Acid; RNA, Messenger | 2008 |
Cerebral glutamine concentration and lactate-pyruvate ratio in patients with acute liver failure.
Topics: Adolescent; Adult; Aged; Astrocytes; Brain; Brain Edema; Critical Care; Female; Glutamine; Humans; Hyperammonemia; Intracranial Hypertension; Lactic Acid; Liver Failure, Acute; Male; Microdialysis; Middle Aged; Mitochondria; Pyruvic Acid; Severity of Illness Index | 2008 |
Simultaneous clinical monitoring of lactic acid, pyruvic acid and ketone bodies in plasma as methoxime/tert-butyldimethylsilyl derivatives by gas chromatography-mass spectrometry in selected ion monitoring mode.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Ketone Bodies; Lactic Acid; Male; Organosilicon Compounds; Oximes; Pyruvic Acid; Reproducibility of Results | 2008 |
Local metabolic, pathophysiological and histological changes in venous ulcers.
Topics: Aged; Bicarbonates; Blood Gas Analysis; Carbon Dioxide; Female; Humans; Hydrogen-Ion Concentration; Lactic Acid; Male; Microscopy, Electron; Middle Aged; Oxygen; Partial Pressure; Pyruvic Acid; Varicose Ulcer | 2007 |
New media for culture to blastocyst.
Topics: Amino Acids; Animals; Blastocyst; Culture Media, Serum-Free; Embryo Culture Techniques; Embryo Transfer; Embryonic Development; Female; Glucose; Humans; Lactic Acid; Male; Mice; Morula; Pyruvic Acid; Serum Albumin; Time Factors | 2009 |
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Topics: Alternative Splicing; Animals; Cell Line, Tumor; Cell Proliferation; Fructosediphosphates; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Lactic Acid; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Oxidative Phosphorylation; Oxygen Consumption; Pyruvate Kinase; Pyruvic Acid | 2008 |
Use of tissue microdialysis to investigate hyperlactataemia following paediatric cardiac surgery.
Topics: Abdominal Wall; Acidosis, Lactic; Biomarkers; Child, Preschool; Epinephrine; Feasibility Studies; Fontan Procedure; Humans; Hydrocortisone; Lactic Acid; Microdialysis; Norepinephrine; Oxygen Consumption; Prospective Studies; Pyruvic Acid; Research Design; Subcutaneous Tissue; Time Factors; Up-Regulation; Ventricular Function | 2008 |
Neuroprotective effect of deep hypothermic circulatory arrest with low priming volume: study in a rabbit model.
Topics: Animals; Blood Volume; Brain Ischemia; Chromatography, High Pressure Liquid; Circulatory Arrest, Deep Hypothermia Induced; Disease Models, Animal; Extracellular Fluid; Follow-Up Studies; Glucose; Glutamic Acid; Hippocampus; In Situ Nick-End Labeling; Lactic Acid; Male; Microdialysis; Microscopy, Electron; Pyruvic Acid; Rabbits; Treatment Outcome | 2008 |
Heterologous expression of pyruvate decarboxylase in Geobacillus thermoglucosidasius.
Topics: Bacillus; Blotting, Western; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Lactic Acid; Pyruvate Decarboxylase; Pyruvic Acid; Zymomonas | 2008 |
The action of extracellular NAD+ in the liver of healthy and tumor-bearing rats: model analysis of the tumor-induced modified response.
Topics: Animals; Cachexia; Carcinoma 256, Walker; Eicosanoids; Extracellular Fluid; Glucose; Hemodynamics; Indomethacin; Lactic Acid; Liver; Male; Models, Biological; NAD; Oxygen Consumption; Protein Synthesis Inhibitors; Pyruvic Acid; Rats; Rats, Wistar | 2008 |
Transcriptional analysis of L-methionine catabolism in the cheese-ripening yeast Yarrowia lipolytica in relation to volatile sulfur compound biosynthesis.
Topics: Chromatography, High Pressure Liquid; Culture Media; DNA Primers; Down-Regulation; Gene Expression Profiling; Lactic Acid; Metabolic Networks and Pathways; Methionine; Oligonucleotide Array Sequence Analysis; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Sulfur Compounds; Up-Regulation; Yarrowia | 2008 |
Neurochemical monitoring of therapeutic effects in large human MCA infarction.
Topics: Craniotomy; Critical Care; Female; Glutamic Acid; Glycerol; Humans; Hypothermia, Induced; Infarction, Middle Cerebral Artery; Lactic Acid; Male; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid; Treatment Outcome | 2008 |
Metabolic failure precedes intracranial pressure rises in traumatic brain injury: a microdialysis study.
Topics: Biomarkers; Brain; Brain Injuries; Glutamic Acid; Glycerol; Humans; Intracranial Hypertension; Lactic Acid; Metabolic Diseases; Microdialysis; Osmolar Concentration; Predictive Value of Tests; Prospective Studies; Pyruvic Acid; Risk Factors | 2008 |
Effect of combined ultrasound and microbubbles treatment in an experimental model of cerebral ischemia.
Topics: Animals; Biomarkers; Brain Ischemia; Glutamic Acid; Glycerol; Infarction, Middle Cerebral Artery; Lactic Acid; Male; Microbubbles; Microdialysis; Middle Cerebral Artery; Models, Animal; Pyruvic Acid; Rats; Rats, Wistar; Sulfur Hexafluoride; Thrombolytic Therapy; Ultrasonography | 2008 |
A possible mechanism for the beneficial effect of ethanol in essential tremor.
Topics: Animals; Brain; Central Nervous System Depressants; Central Nervous System Stimulants; Essential Tremor; Ethanol; Glutamic Acid; Glycerol; Harmaline; Lactic Acid; Male; Microdialysis; N-Methylaspartate; Pyruvic Acid; Rats; Rats, Wistar | 2008 |
Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes.
Topics: Adenine Nucleotides; Animals; Cell Separation; Dihydroxyacetone; Electron Transport; Fluoresceins; Fluorescent Dyes; Glucose; Glycolysis; Hepatocytes; Hydrogen Peroxide; In Vitro Techniques; Lactic Acid; Male; Mitochondria, Liver; Oxidants; Perfusion; Protein Kinases; Pyruvate Kinase; Pyruvic Acid; Rats; Reactive Oxygen Species; Silybin; Silymarin | 2008 |
Interstitial glucose concentration in insulin-resistant human skeletal muscle: influence of one bout of exercise and of local perfusion with insulin or vanadate.
Topics: Bicycling; Exercise; Extracellular Fluid; Glucose; Heart Rate; Humans; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Resistance; Lactic Acid; Leg; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Pyruvic Acid; Rest; Urea; Vanadates | 2008 |
Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies.
Topics: Alanine; Animals; Carbon Isotopes; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2008 |
Probing the role of dynamics in hydride transfer catalyzed by lactate dehydrogenase.
Topics: Catalysis; Computer Simulation; Enzyme Activation; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Light; Models, Chemical; Models, Molecular; NAD; Pyruvic Acid | 2008 |
Decreases in myocardial glucose and increases in pyruvate but not ischaemia are observed during porcine endotoxaemia.
Topics: Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Endotoxemia; Glucose; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardium; Oxygen; Pulmonary Artery; Pyruvic Acid; Stroke Volume; Swine; Ventricular Function, Left | 2008 |
Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. I. Interrelation between gluconeogenesis and cataplerosis; formation of methoxamates from aminooxyacetate and ketoacids.
Topics: Aminooxyacetic Acid; Animals; Carbon Isotopes; Citric Acid Cycle; Gluconeogenesis; Keto Acids; Lactic Acid; Liver; Male; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Succinates | 2008 |
Effects of hypoxia on relationships between cytosolic and mitochondrial NAD(P)H redox and superoxide generation in coronary arterial smooth muscle.
Topics: Animals; Cattle; Coronary Vessels; Cytosol; Fluorescent Dyes; Hypoxia; In Vitro Techniques; Lactic Acid; Membrane Potentials; Microscopy, Fluorescence; Mitochondria, Muscle; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; Pyruvic Acid; Reactive Oxygen Species; Subcellular Fractions; Superoxides | 2008 |
Central lactate metabolism regulates food intake.
Topics: Animals; Body Weight; Central Nervous System; Eating; Lactic Acid; Male; Oxamic Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2008 |
Pyruvate and oxygen consumption throughout the growth and development of murine oocytes.
Topics: Analysis of Variance; Animals; Culture Media; Female; Glucose; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Oocytes; Ovarian Follicle; Oxygen Consumption; Pyruvic Acid; Statistics, Nonparametric | 2009 |
Cerebral metabolism during air transport of patients after surgery for malignant glioma.
Topics: Air Ambulances; Brain; Brain Neoplasms; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Microdialysis; Pyruvic Acid; Transportation of Patients | 2008 |
Good bye "lactic acid"; hello lactate and acid.
Topics: Acidosis; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chemical Phenomena; Chemistry, Physical; Exercise; Humans; Keto Acids; Lactic Acid; Pyruvic Acid | 2008 |
Free jejunal flaps can be monitored by use of microdialysis.
Topics: Aged; Esophageal Neoplasms; Esophagoplasty; Esophagus; Female; Glucose; Humans; Ischemia; Jejunum; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Pyruvic Acid; Surgical Flaps | 2008 |
Significant [C3a] increase in free flaps after prolonged ischemia.
Topics: Adolescent; Adult; Chemokine CCL5; Complement C3a; Extracellular Fluid; Female; Glucose; Glycerol; Humans; Interleukin-18; Ischemia; Lactic Acid; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Prospective Studies; Pyruvic Acid | 2008 |
Amyloid-beta dynamics correlate with neurological status in the injured human brain.
Topics: Amyloid beta-Peptides; Brain; Brain Injuries; Extracellular Fluid; Glasgow Coma Scale; Glucose; Humans; Intracranial Hypertension; Lactic Acid; Microdialysis; Peptide Fragments; Pyruvic Acid | 2008 |
Metabolic and functional characterization of human adipose-derived stem cells in tissue engineering.
Topics: Adipose Tissue; Alkaline Phosphatase; Bone and Bones; Cell Death; Cell Division; Cells, Cultured; Glucose; Humans; Lactic Acid; Multipotent Stem Cells; Pyruvic Acid; Tissue and Organ Harvesting; Tissue Engineering | 2008 |
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury.
Topics: Adolescent; Adult; Atrophy; Biomarkers; Brain Diseases; Brain Injuries; Chronic Disease; Cohort Studies; Critical Illness; Female; Follow-Up Studies; Frontal Lobe; Glasgow Coma Scale; Humans; Injury Severity Score; Intensive Care Units; Lactic Acid; Male; Microdialysis; Middle Aged; Predictive Value of Tests; Pyruvic Acid; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Tomography, X-Ray Computed | 2008 |
Yak lactate dehydgogenase A4: purification, properties, and cDNA cloning.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Cloning, Molecular; DNA, Complementary; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Molecular; Molecular Sequence Data; Muscle, Skeletal; Pyruvic Acid; Sequence Homology, Amino Acid | 2008 |
Liver glycogen metabolism during short-term insulin-induced hypoglycemia in fed rats.
Topics: Animals; Enzyme Activation; Feeding Behavior; Glucagon; Glucose; Glycogen Phosphorylase; Glycogen Synthase; Glycogenolysis; Glycolysis; Hypoglycemia; In Vitro Techniques; Injections, Intraperitoneal; Insulin; Isoproterenol; Lactic Acid; Liver; Liver Glycogen; Male; Pyruvic Acid; Rats; Rats, Wistar; Time Factors | 2008 |
Nonischemic energy metabolic crisis in acute brain injury.
Topics: Biomarkers; Brain Injuries; Critical Care; Critical Illness; Energy Metabolism; Female; Glasgow Coma Scale; Humans; Injury Severity Score; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Prognosis; Pyruvic Acid; Sensitivity and Specificity; Survival Rate | 2008 |
Neuroprotective effects of erythropoietin on acute metabolic and pathological changes in experimentally induced neurotrauma.
Topics: Acute Disease; Animals; Brain Injuries; Disease Models, Animal; Energy Metabolism; Erythropoietin; Glucose; Glutamic Acid; Lactic Acid; Microdialysis; Neuroprotective Agents; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2008 |
Effect of crude sulphated polysaccharide from brown algae against acetaminophen-induced toxicity in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Blood Glucose; Cell Death; Drug Overdose; Globulins; Kidney; Lactic Acid; Liver; Liver Function Tests; Liver Glycogen; Male; Phaeophyceae; Polysaccharides; Pyruvic Acid; Rats; Rats, Wistar; Serum Albumin | 2008 |
Insight into the reduction of pyruvic acid to lactic acid over Cu{110}: the crucial role of intramolecular tunneling in direct hydrogenation.
Topics: Adsorption; Copper; Hydrogenation; Lactic Acid; Models, Chemical; Models, Molecular; Oxidation-Reduction; Pyruvic Acid; Thermodynamics; Vacuum | 2008 |
The effect of lactates of Na and Ca on the mouse and its approximation to that of pyruvate.
Topics: Calcium; Calcium Compounds; Calcium, Dietary; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Sodium; Sodium Lactate | 1947 |
The blood lactate-pyruvate relationship in various physiologic and pathologic states.
Topics: Blood; Humans; Lactic Acid; Pyruvates; Pyruvic Acid | 1948 |
Muscle lactic acid and pyruvic acid (striated muscle) in castration.
Topics: Castration; Humans; Lactic Acid; Male; Muscles; Orchiectomy; Pyruvic Acid | 1947 |
Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: a microdialysis study.
Topics: Adult; Aged; Blood Glucose; Brain; Brain Injuries; Female; Glucose; Hospitals, University; Humans; Hypoglycemic Agents; Insulin; Intensive Care Units; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Retrospective Studies | 2008 |
Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver.
Topics: Age Factors; Aging; Aldehyde Reductase; Animals; Caloric Restriction; Fructose; Glucose; L-Iditol 2-Dehydrogenase; Lactic Acid; Liver; Malates; Male; Mice; Mice, Inbred C57BL; NAD; NADP; Oxidation-Reduction; Pyruvic Acid; Sorbitol | 2009 |
Nanoparticle-supported multi-enzyme biocatalysis with in situ cofactor regeneration.
Topics: Animals; Biocatalysis; Cattle; Coenzymes; Enzymes, Immobilized; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Motion; NAD; Nanoparticles; Pyruvic Acid; Rabbits; Silicon Dioxide | 2009 |
Enantioselective oxidation of racemic lactic acid to D-lactic acid and pyruvic acid by Pseudomonas stutzeri SDM.
Topics: Biotechnology; Biotransformation; Catalysis; Lactic Acid; Oxidation-Reduction; Pseudomonas stutzeri; Pyruvic Acid | 2009 |
Restoration of electron transport without proton pumping in mammalian mitochondria.
Topics: Animals; Cell Line; Dichloroacetic Acid; DNA, Mitochondrial; Electron Transport; Electron Transport Complex I; Fungal Proteins; Humans; Lactic Acid; Mice; Mitochondria; Mitochondrial Proteins; NADH Dehydrogenase; Oxidation-Reduction; Oxidoreductases; Oxygen; Plant Proteins; Proton Pumps; Protons; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Transformation, Genetic; Ubiquinone; Uridine | 2008 |
Metabolic flux analysis of Shewanella spp. reveals evolutionary robustness in central carbon metabolism.
Topics: Acetic Acid; Carbon; Carbon Isotopes; Culture Media; Lactic Acid; Pyruvic Acid; Shewanella | 2009 |
Properties and role of glyceraldehyde-3-phosphate dehydrogenase in the control of fermentation pattern and growth in a ruminal bacterium, Streptococcus bovis.
Topics: Culture Media; Fermentation; Glucose; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Pyruvic Acid; Streptococcus bovis | 2009 |
[Microdialysis: experience in postoperative monitoring of 30 free flaps].
Topics: Adult; Aged; Biomarkers; Blood Glucose; Facial Neoplasms; Female; Graft Survival; Humans; Ischemia; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Plastic Surgery Procedures; Postoperative Complications; Prospective Studies; Pyruvic Acid; Surgical Flaps; Thrombosis | 2009 |
Ultrasonic cardiac output monitoring and microcirculation: is it worthwhile to consider in reconstructive microsurgery?
Topics: Animals; Cardiac Output; Female; Glucose; Graft Occlusion, Vascular; Humans; Lactic Acid; Microcirculation; Microdialysis; Models, Biological; Monitoring, Physiologic; Pyruvic Acid; Rectus Abdominis; Regional Blood Flow; Shock; Skin; Surgical Flaps; Swine | 2009 |
Pathophysiology of the transient temporal lobe lesion in a patient with Menkes disease.
Topics: Biomarkers; Ceruloplasmin; Copper; Diffusion Magnetic Resonance Imaging; Electroencephalography; Electron Transport Complex IV; Humans; Infant; Lactic Acid; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Menkes Kinky Hair Syndrome; Pyruvic Acid; Temporal Lobe | 2008 |
Limb ischemia after EVAR: an effect of the obstructing introducer?
Topics: Abdomen; Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Arterial Occlusive Diseases; Ascitic Fluid; Biomarkers; Equipment Design; Female; Humans; Iliac Artery; Ischemia; Lactic Acid; Lower Extremity; Male; Microdialysis; Middle Aged; Pilot Projects; Pyruvic Acid; Splanchnic Circulation; Time Factors; Treatment Outcome; Vascular Surgical Procedures | 2008 |
A combined microdialysis and FDG-PET study of glucose metabolism in head injury.
Topics: Adolescent; Adult; Aged; Biomarkers; Brain; Brain Injuries; Energy Metabolism; Extracellular Fluid; Female; Fluorodeoxyglucose F18; Glucose; Glycolysis; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Positron-Emission Tomography; Predictive Value of Tests; Pyruvic Acid; Young Adult | 2009 |
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Time Factors; Weaning | 2009 |
Microdialysis monitoring of porcine liver metabolism during warm ischemia with arterial and portal clamping.
Topics: Anesthesia; Animals; Constriction; Female; Glucose; Halothane; Hepatic Artery; Lactic Acid; Liver; Liver Circulation; Microdialysis; Midazolam; Monitoring, Physiologic; Portal Vein; Pyruvic Acid; Swine | 2009 |
Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite.
Topics: Alanine; Anaerobiosis; Animals; Energy Metabolism; Glucose; Glycerol; Humans; Lactic Acid; NAD; Oxidation-Reduction; Plasmodium falciparum; Pyruvic Acid; Spectrum Analysis | 2009 |
Assessment of mitochondrial respiratory chain function in hyperphenylalaninaemia.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Cell Line, Tumor; Cells, Cultured; Culture Media; Electron Transport; Female; Humans; Lactic Acid; Male; Middle Aged; Mitochondrial Diseases; Phenylalanine; Phenylketonurias; Pyruvic Acid; Tremor; Tyrosine; Ubiquinone; Young Adult | 2009 |
Glutamate is the major anaplerotic substrate in the tricarboxylic acid cycle of isolated rumen epithelial and duodenal mucosal cells from beef cattle.
Topics: Animals; Carbon Isotopes; Cattle; Citric Acid Cycle; Diet; Duodenum; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Glucose; Glutamic Acid; Glutamine; Intestinal Mucosa; Lactic Acid; Leucine; Male; Pyruvic Acid; Rumen; Valine | 2009 |
Relevance of intracranial hypertension for cerebral metabolism in aneurysmal subarachnoid hemorrhage. Clinical article.
Topics: Adult; Brain; Brain Diseases; Craniotomy; Decompression, Surgical; Energy Metabolism; Female; Glutamic Acid; Glycerol; Humans; Intracranial Hypertension; Lactic Acid; Male; Microdialysis; Middle Aged; Point-of-Care Systems; Prognosis; Prospective Studies; Pyruvic Acid; Retrospective Studies; Subarachnoid Hemorrhage; Treatment Outcome | 2009 |
Selective antegrade cerebral perfusion at two different temperatures compared to hypothermic circulatory arrest--an experimental study in the pig with microdialysis.
Topics: Animals; Biomarkers; Body Temperature; Cardiopulmonary Bypass; Cerebrovascular Circulation; Circulatory Arrest, Deep Hypothermia Induced; Energy Metabolism; Glucose; Glycerol; Lactic Acid; Microdialysis; Models, Animal; Monitoring, Intraoperative; Perfusion; Prosencephalon; Pyruvic Acid; Sus scrofa; Time Factors | 2009 |
Cerebral energy failure following experimental cardiac arrest Hypothermia treatment reduces secondary lactate/pyruvate-ratio increase.
Topics: Animals; Brain; Brain Ischemia; Cardiopulmonary Resuscitation; Cerebrovascular Circulation; Disease Models, Animal; Energy Metabolism; Female; Glutamic Acid; Heart Arrest; Hypothermia, Induced; Intracranial Pressure; Lactic Acid; Male; Oxygen Consumption; Pyruvic Acid; Random Allocation; Rewarming; Swine; Treatment Outcome | 2009 |
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
Topics: Acetylcarnitine; Animals; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Energy Metabolism; Glutamic Acid; In Vitro Techniques; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Models, Cardiovascular; Myocardial Ischemia; Myocardium; Perfusion; Pyruvic Acid; Rats; Rats, Wistar | 2009 |
Mitochondrial bioenergetic background confers a survival advantage to HepG2 cells in response to chemotherapy.
Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Cell Differentiation; Cell Proliferation; Cell Respiration; Cell Survival; Energy Metabolism; Ethylnitrosourea; Glucose; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Membrane Potential, Mitochondrial; Mitochondria; Osteosarcoma; Oxidative Phosphorylation; Pyruvic Acid; Tumor Cells, Cultured | 2009 |
Changes in brain biochemistry and oxygenation in the zone surrounding primary intracerebral hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Blood Pressure; Brain; Brain Chemistry; Cerebral Hemorrhage; Female; Glasgow Outcome Scale; Glycerol; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Pyruvic Acid; Respiration, Artificial; Retrospective Studies; Time Factors | 2008 |
Redox dependence and compartmentation of [13C]pyruvate in the brain of deuterated rats bearing implanted C6 gliomas.
Topics: Animals; Astrocytes; Brain Chemistry; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Cerebral Cortex; Deuterium; Glioma; Glucose; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Methylation; Neoplasm Transplantation; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar | 2009 |
Transfer of reducing equivalents across the mitochondrial membrane. I. Hydrogen transfer mechanisms involved in the reduction of pyruvate to lactate in isolated liver cells.
Topics: Amobarbital; Animals; Biological Transport; Gluconeogenesis; Hepatocytes; Hydrogen; Hypnotics and Sedatives; Lactic Acid; Male; Mitochondrial Membranes; Oleic Acid; Oxidation-Reduction; Pyruvic Acid; Quinolinic Acid; Rats; Rats, Sprague-Dawley | 1974 |
Changes in cerebral blood flow, cerebral metabolites, and breathing movements in the sheep fetus following asphyxia produced by occlusion of the umbilical cord.
Topics: Animals; Asphyxia; Biomarkers; Blood Flow Velocity; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Disease Models, Animal; Electroencephalography; Energy Metabolism; Female; Fetal Blood; Fetal Hypoxia; Gestational Age; Glucose; Glycerol; Heart Rate; Hydrogen-Ion Concentration; Lactic Acid; Microdialysis; Oxygen; Pregnancy; Pyruvic Acid; Respiratory Mechanics; Sheep; Time Factors; Umbilical Cord | 2009 |
Microdialysis of paraspinal muscle in healthy volunteers and patients underwent posterior lumbar fusion surgery.
Topics: Adult; Aged; Case-Control Studies; Female; Glucose; Glycerol; Humans; Lactic Acid; Lumbar Vertebrae; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Posture; Pyruvic Acid; Spinal Fusion; Young Adult | 2009 |
Relationship between intracranial hemodynamics and microdialysis markers of energy metabolism and glutamate-glutamine turnover in patients with subarachnoid hemorrhage. Clinical article.
Topics: Aged; Biomarkers; Blood Pressure; Cerebrovascular Circulation; Critical Care; Energy Metabolism; Female; Glutamic Acid; Glutamine; Hemodynamics; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid; Retrospective Studies; Subarachnoid Hemorrhage | 2009 |
Metabolic responses in ischemic myocardium after inhalation of carbon monoxide.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Blood Pressure; Carbon Monoxide; Carboxyhemoglobin; Central Venous Pressure; Energy Metabolism; Female; Glucose; Heart Rate; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardium; Protective Agents; Pyruvic Acid; Swine | 2009 |
Evidence for the participation of the stimulated sympathetic nervous system in the regulation of carnitine blood levels of soccer players during a game.
Topics: Adolescent; Antioxidants; Biomarkers; Carnitine; Chromatography, High Pressure Liquid; Creatine Kinase; Epinephrine; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Norepinephrine; Pyruvic Acid; Soccer; Sympathetic Nervous System; Tandem Mass Spectrometry; Time Factors; Young Adult | 2009 |
eComment: Selective antegrade cerebral perfusion and metabolic suppression.
Topics: Animals; Biomarkers; Blood-Brain Barrier; Body Temperature; Brain; Cardiopulmonary Bypass; Cerebrovascular Circulation; Circulatory Arrest, Deep Hypothermia Induced; Energy Metabolism; Glucose; Glycerol; Lactic Acid; Microdialysis; Models, Animal; Monitoring, Intraoperative; Perfusion; Pyruvic Acid; Time Factors | 2009 |
Pre-ischemic treatment with memantine reversed the neurochemical and behavioural parameters but not energy metabolites in middle cerebral artery occluded rats.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Brain; Glutamate-Ammonia Ligase; Glutamine; Glutathione; Lactic Acid; Male; Memantine; Middle Cerebral Artery; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2009 |
Improving the recovery of S100B protein in cerebral microdialysis: implications for multimodal monitoring in neurocritical care.
Topics: Brain Injuries; Catheterization; Enzyme-Linked Immunosorbent Assay; Extracellular Fluid; Glucose; Humans; In Vitro Techniques; Lactic Acid; Microdialysis; Monitoring, Physiologic; Nerve Growth Factors; Pyruvic Acid; Recovery of Function; Reproducibility of Results; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2009 |
Metabolic and histologic effects of sodium pyruvate treatment in the rat after cortical contusion injury.
Topics: Analysis of Variance; Animals; Brain; Brain Injuries; Cell Count; Glucose; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2009 |
Prior heavy exercise elevates pyruvate dehydrogenase activity and muscle oxygenation and speeds O2 uptake kinetics during moderate exercise in older adults.
Topics: Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Diphosphate; Adenosine Triphosphate; Age Factors; Aged; Exercise; Humans; Kinetics; Lactic Acid; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxygen; Oxygen Consumption; Phosphocreatine; Pulmonary Ventilation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Regional Blood Flow; Spectroscopy, Near-Infrared; Up-Regulation | 2009 |
Cerebral metabolism during deep hypothermic circulatory arrest vs moderate hypothermic selective cerebral perfusion in a piglet model: a microdialysis study.
Topics: Animals; Brain; Cerebral Revascularization; Circulatory Arrest, Deep Hypothermia Induced; Energy Metabolism; Female; Glucose; Lactic Acid; Male; Microdialysis; Models, Animal; Oxygen; Partial Pressure; Pyruvic Acid; Random Allocation; Swine; Treatment Outcome | 2009 |
Pyruvate protects against experimental stroke via an anti-inflammatory mechanism.
Topics: Animals; Body Weight; Cell Count; Disease Models, Animal; Ectodysplasins; Encephalitis; Infarction, Middle Cerebral Artery; Lactic Acid; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Microglia; Motor Activity; Nervous System Diseases; Neutrophil Infiltration; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Psychomotor Performance; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Tetrazolium Salts | 2009 |
Effects of reduced oxygen and glucose levels on ocular cells in vitro: implications for tissue models.
Topics: Animals; Astrocytes; Cell Proliferation; Cells, Cultured; Glaucoma, Open-Angle; Glucose; Glutamic Acid; Lactic Acid; Models, Biological; Optic Disk; Oxygen; Pyruvic Acid; Rats; Sclera; Swine; Tissue Engineering | 2010 |
Levosimendan cardioprotection in acutely beta-1 adrenergic receptor blocked open chest pigs.
Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Clinical Protocols; Female; Glucose; Glycerol; Hemodynamics; Hydrazones; Lactic Acid; Male; Metoprolol; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyridazines; Pyruvic Acid; Simendan; Swine; Thoracic Surgical Procedures; Treatment Outcome | 2010 |
Metabolic aspects of neonatal rat islet hypoxia tolerance.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cyclic AMP; Glucose; Glycolysis; Hypoxia; Insulin; Insulin Secretion; Islets of Langerhans; Lactic Acid; Oxygen; Pyruvic Acid; Rats | 2010 |
Effect of pyruvate, lactate and insulin on ATP supply and demand in unpaced perfused rat heart.
Topics: Adenosine Triphosphate; Animals; Glucose; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Myocardium; Perfusion; Phosphocreatine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sweetening Agents | 2009 |
[Effects of ethyl pyruvate on injuries of sepsis in mice].
Topics: Alkaline Phosphatase; Animals; Disease Models, Animal; Intestines; Lactic Acid; Lung; Male; Mice; Pyruvates; Pyruvic Acid; Sepsis; Uric Acid | 2009 |
Glutamate metabolic pathways and retinal function.
Topics: Animals; Aspartate Aminotransferases; Electroretinography; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Homeostasis; Immunohistochemistry; Ketoglutaric Acids; Lactic Acid; Methionine Sulfoximine; Photoreceptor Cells, Vertebrate; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Succinic Acid; Synaptic Transmission; Vision, Ocular | 2009 |
1H-nuclear magnetic resonance spectroscopy-based metabolic assessment in a rat model of obesity induced by a high-fat diet.
Topics: Acetoacetates; Acetone; Animals; Betaine; Citric Acid; Dietary Fats; Disease Models, Animal; Glycine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Multivariate Analysis; Obesity; Protons; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Taurine | 2009 |
Forty-five-year evolution of stat blood and plasma lactate measurement to guide critical care.
Topics: Blood Chemical Analysis; Critical Care; History, 20th Century; History, 21st Century; Humans; Lactic Acid; Pyruvic Acid | 2009 |
In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy-related molecules, growth factors and cytokines.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Cytokines; Dexamethasone; Energy Metabolism; Female; Gene Expression Regulation, Neoplastic; Glioma; Glucose; Glutamic Acid; Glycerol; Humans; Intercellular Signaling Peptides and Proteins; Lactic Acid; Male; Matrix Metalloproteinase 9; Microdialysis; Middle Aged; Pyruvic Acid; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2010 |
Coupling between the blood lactate-to-pyruvate ratio and MCA Vmean at the onset of exercise in humans.
Topics: Adolescent; Adult; Blood Flow Velocity; Blood Pressure; Catheters, Indwelling; Cerebrovascular Circulation; Exercise; Heart Rate; Humans; Lactic Acid; Male; Middle Cerebral Artery; Models, Biological; Oxygen Consumption; Pyruvic Acid; Signal Processing, Computer-Assisted; Time Factors; Ultrasonography, Doppler, Transcranial | 2009 |
Establishment and characterization of a novel method for evaluating gluconeogenesis using hepatic cell lines, H4IIE and HepG2.
Topics: Animals; Cell Culture Techniques; Cell Line, Tumor; Fluorometry; Gluconeogenesis; Glucose; Hepatocytes; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Metformin; Pyruvic Acid; Rats; Up-Regulation | 2009 |
Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia.
Topics: Analysis of Variance; Anilides; Animals; Astrocytes; Benzophenones; Cell Shape; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Hypoglycemic Agents; Lactic Acid; Neurons; Pioglitazone; PPAR gamma; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiazolidinediones; Tyrosine | 2009 |
Urea clearance: a new method to register local changes in blood flow in rat skeletal muscle based on microdialysis.
Topics: Animals; Blood Glucose; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Norepinephrine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Urea; Vasoconstrictor Agents | 2010 |
Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells.
Topics: Biological Transport; Breast Neoplasms; Carbon Isotopes; Cell Hypoxia; Cell Survival; Humans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Monocarboxylic Acid Transporters; Pyruvic Acid; Quercetin; Reproducibility of Results; Tumor Cells, Cultured | 2009 |
Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice.
Topics: Alanine; Algorithms; Animals; Carbon Isotopes; Computer Simulation; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolic Clearance Rate; Mice; Mice, Transgenic; Models, Biological; Prostatic Neoplasms; Pyruvic Acid; Rats | 2010 |
A method for lactate and pyruvate determination in filter-paper dried blood spots.
Topics: Calibration; Chromatography, Liquid; Enzyme Assays; Filtration; Humans; Infant, Newborn; Lactic Acid; Paper; Pyruvic Acid; Reference Standards; Reference Values; Regression Analysis; Tandem Mass Spectrometry | 2009 |
Characterization of the L-lactate dehydrogenase from Aggregatibacter actinomycetemcomitans.
Topics: Bacterial Proteins; Biological Transport; Carbon; Gene Expression Regulation, Enzymologic; Glucose; Gram-Negative Bacteria; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Biological; NAD; Protein Structure, Tertiary; Pyruvic Acid | 2009 |
Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycolysis; Humans; Lactic Acid; Male; Oxidation-Reduction; Prostatic Neoplasms; Pyruvic Acid; Reactive Oxygen Species; Spheroids, Cellular | 2010 |
[Ishemic-reperfusion syndrome prophylaxis in general hypothermia in experiment].
Topics: Animals; Antioxidants; Body Temperature; Catalase; Female; Glucose; Glutathione; Homeostasis; Hypothermia; Lactic Acid; Lipid Peroxides; Male; Pyruvic Acid; Quercetin; Rats; Reperfusion Injury; Sulfhydryl Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Treatment Outcome | 2009 |
Complications but not obesity or diabetes mellitus have impact on the intraperitoneal lactate/pyruvate ratio measured by microdialysis.
Topics: Aged; Aged, 80 and over; Diabetes Complications; Female; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Obesity; Peritoneum; Postoperative Complications; Pyruvic Acid; Risk Factors | 2010 |
Prebiotic metabolism: production by mineral photoelectrochemistry of alpha-ketocarboxylic acids in the reductive tricarboxylic acid cycle.
Topics: Carboxylic Acids; Citric Acid Cycle; Earth, Planet; Electrochemistry; Evolution, Chemical; Ketoglutaric Acids; Lactic Acid; Light; Minerals; Origin of Life; Oxidation-Reduction; Photochemistry; Pyruvic Acid | 2009 |
Glycolytic metabolism and tumour response to fractionated irradiation.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Dose Fractionation, Radiation; Glucose; Glycolysis; Head and Neck Neoplasms; Humans; Lactic Acid; Mice; Pyruvic Acid | 2010 |
Structure of D-lactate dehydrogenase from Aquifex aeolicus complexed with NAD(+) and lactic acid (or pyruvate).
Topics: Bacteria; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Genes, Bacterial; Lactate Dehydrogenases; Lactic Acid; Lactobacillus helveticus; Models, Molecular; NAD; Protein Conformation; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Pyruvic Acid; Recombinant Proteins; Static Electricity | 2009 |
Resuscitation of severely asphyctic newborn pigs with cardiac arrest by using 21% or 100% oxygen.
Topics: Animals; Animals, Newborn; Asphyxia; Blood Pressure; Carbon Dioxide; Cardiopulmonary Resuscitation; Female; Heart Arrest; Heart Rate; Hemodynamics; Interleukin-1beta; Lactic Acid; Male; Oxygen; Pyruvic Acid; Swine | 2010 |
Fetal cerebral energy metabolism and electrocardiogram during experimental umbilical cord occlusion and resuscitation.
Topics: Animals; Brain; Brain Chemistry; Cardiopulmonary Resuscitation; Disease Models, Animal; Electrocardiography; Energy Metabolism; Female; Fetal Hypoxia; Glutamic Acid; Heart Arrest; Lactic Acid; Pregnancy; Pyruvic Acid; Sheep; Umbilical Cord | 2010 |
Utility of microdialysis to detect the lactate/pyruvate ratio in subcutaneous tissue for the reliable monitoring of hemorrhagic shock.
Topics: Animals; Blood Pressure; Early Diagnosis; Hypotension; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Oxygen; Pentosephosphates; Pyruvic Acid; Rats; Rats, Wistar; Shock, Hemorrhagic; Subcutaneous Fat, Abdominal | 2009 |
Brain interstitial fluid TNF-alpha after subarachnoid hemorrhage.
Topics: Adult; Blood Glucose; Brain; Cohort Studies; Coma; Extracellular Fluid; Female; Glucose; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Subarachnoid Hemorrhage; Time Factors; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha | 2010 |
Systemic glucose and brain energy metabolism after subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Brain; Critical Care; Energy Metabolism; Equipment Design; Female; Glasgow Coma Scale; Hospital Mortality; Humans; Hypoglycemia; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen Consumption; Prognosis; Pyruvic Acid; Signal Processing, Computer-Assisted; Subarachnoid Hemorrhage; Subarachnoid Hemorrhage, Traumatic | 2010 |
Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury.
Topics: Adolescent; Adult; Blood Glucose; Brain; Brain Injuries; Female; Glutamic Acid; Humans; Insulin; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Young Adult | 2010 |
Reduced caloric intake during endotoxemia reduces arginine availability and metabolism.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Endotoxins; Energy Intake; Escherichia coli; Lactic Acid; Lipopolysaccharides; Nitric Oxide; Protein-Energy Malnutrition; Proteins; Pyruvic Acid; Random Allocation; Swine | 2010 |
Impaired glucose tolerance in patients with amyotrophic lateral sclerosis.
Topics: Adiponectin; Adolescent; Adult; Aged; Amyotrophic Lateral Sclerosis; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Interleukin-6; Lactic Acid; Leptin; Male; Middle Aged; Pyruvic Acid; Tumor Necrosis Factor-alpha; Young Adult | 2010 |
Magnetic resonance spectroscopy for evaluation of liposome-encapsulated hemoglobin as a resuscitation fluid.
Topics: Animals; Aspartic Acid; Brain; Cerebral Hemorrhage; Drug Compounding; Energy Metabolism; Feasibility Studies; Hemoglobins; Humans; Lactic Acid; Liposomes; Liquid Ventilation; Magnetic Resonance Spectroscopy; Male; Neuroprotective Agents; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2010 |
Metabolic crisis after traumatic brain injury is associated with a novel microdialysis proteome.
Topics: Blood Glucose; Brain; Brain Injuries; Brain Ischemia; Cerebral Hemorrhage, Traumatic; Energy Metabolism; Extracellular Fluid; Follow-Up Studies; Frontal Lobe; Glasgow Coma Scale; Humans; Hypoglycemia; Intracranial Pressure; Lactic Acid; Magnetic Resonance Imaging; Microdialysis; Monitoring, Physiologic; Proteomics; Pyruvic Acid; Reference Values; Signal Processing, Computer-Assisted; Tandem Mass Spectrometry; Temporal Lobe; Tomography, X-Ray Computed | 2010 |
Micro determination of lactic acid and pyruvic acid in the liver.
Topics: Humans; Lactic Acid; Liver; Pyruvic Acid | 1947 |
Distribution of intravenously injected glutamate, lactate, pyruvate, and succinate between blood and brain.
Topics: Blood; Blood Chemical Analysis; Brain; Glutamates; Glutamic Acid; Humans; Injections, Intravenous; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Succinic Acid | 1947 |
Fatal cerebral edema associated with serine deficiency in CSF.
Topics: Biomarkers; Blood Glucose; Brain; Brain Edema; Child; Child, Preschool; Energy Metabolism; Fatal Outcome; Female; Humans; Ketone Bodies; Lactic Acid; Neurotoxicity Syndromes; Predictive Value of Tests; Pyruvic Acid; Serine | 2010 |
The blood lactate-pyruvate relationship in various physiologic and pathologic states.
Topics: Blood; Humans; Lactic Acid; Pyruvates; Pyruvic Acid | 1947 |
L-lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative L-lactate oxidase localized in the intermembrane space.
Topics: Animals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Intracellular Membranes; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria; Mitochondria, Liver; Mixed Function Oxygenases; NAD; Oxidants; Pyruvic Acid; Rats; Rats, Wistar | 2010 |
Lactate and adenosine triphosphate in the extender enhance the cryosurvival of rat epididymal sperm.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Cryopreservation; Cryoprotective Agents; Epididymis; Glucose; Lactic Acid; Male; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar; Semen Preservation; Solutions; Sperm Motility; Spermatozoa | 2010 |
Effects of changes in the concentration of systemic progesterone on ions, amino acids and energy substrates in cattle oviduct and uterine fluid and blood.
Topics: Amino Acids; Animals; Blood Glucose; Body Fluids; Cattle; Estrous Cycle; Fallopian Tubes; Female; Ions; Lactic Acid; Progesterone; Pyruvic Acid; Regression Analysis; Uterus | 2010 |
Mitochondrial dysfunction induced by statin contributes to endothelial dysfunction in patients with coronary artery disease.
Topics: Aged; Biomarkers; Brachial Artery; Coronary Artery Disease; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactic Acid; Male; Mitochondria, Heart; Mitochondrial Diseases; Pyruvic Acid; Regional Blood Flow; Simvastatin; Vasodilation | 2010 |
Inhibition of acute lung inflammation and injury is a target of brain cooling after heatstroke injury.
Topics: Acute Lung Injury; Animals; Body Temperature Regulation; Brain; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Glutamic Acid; Heat Stroke; Hypothermia, Induced; Immunoenzyme Techniques; Inflammation Mediators; Lactic Acid; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Oxygen Consumption; Peroxidase; Pyruvic Acid; Rats; Regional Blood Flow | 2010 |
Traumatic brain injury and metabolism.
Topics: Blood Flow Velocity; Blood Glucose; Brain; Brain Injuries; Craniotomy; Decompression, Surgical; Energy Metabolism; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Mitochondrial Diseases; Oxygen Consumption; Prognosis; Pyruvic Acid; Treatment Outcome | 2010 |
Hyperlactic acidosis as metabolic side-effect of albuterol and theophylline in acute severe asthma.
Topics: Acidosis, Lactic; Administration, Inhalation; Adolescent; Albuterol; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Blood Gas Analysis; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Lactic Acid; Prednisolone; Pyruvic Acid; Theophylline | 2010 |
Progestin exposure before gonadotropin stimulation improves embryo development after in vitro fertilization in the domestic cat.
Topics: Animals; Cats; Female; Fertilization in Vitro; Glucose; Gonadotropins; Lactic Acid; Male; Oocytes; Ovarian Follicle; Ovulation; Pregnancy; Progestins; Pyruvic Acid; Random Allocation; Statistics, Nonparametric | 2010 |
High-resolution nuclear magnetic resonance spectroscopic study of metabolites in the cerebrospinal fluid of patients with cervical myelopathy and lumbar radiculopathy.
Topics: Acetic Acid; Adult; Aged; Aged, 80 and over; Alanine; Cervical Vertebrae; Citric Acid; Female; Glutamic Acid; Humans; Lactic Acid; Lumbar Vertebrae; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyruvic Acid; Radiculopathy; Spinal Cord Compression | 2010 |
Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress.
Topics: Adenosine Triphosphate; Carbon; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Culture Media; Energy Metabolism; Escherichia coli; Glucose; Lactic Acid; Pyruvic Acid; Stress, Physiological; Thiamine Triphosphate; Uncoupling Agents | 2010 |
Brain energy metabolism in patients with spontaneous subarachnoid hemorrhage and global cerebral edema.
Topics: Biomarkers; Brain; Brain Chemistry; Brain Edema; Energy Metabolism; Extracellular Fluid; Glucose; Humans; Lactic Acid; Microdialysis; Oxidative Phosphorylation; Predictive Value of Tests; Pyruvic Acid; Subarachnoid Hemorrhage; Tomography, X-Ray Computed; Up-Regulation | 2010 |
Metabolic profiling of muscle contraction in lean compared with obese rodents.
Topics: Acetyl-CoA Carboxylase; Animals; Biological Transport; Carnitine; Glucose; Glycogen; Lactic Acid; Lipids; Malonyl Coenzyme A; Muscle Contraction; Muscle, Skeletal; Obesity; Pyruvic Acid; Rats; Rats, Zucker; Sciatic Nerve; Triglycerides | 2010 |
Redirecting reductant flux into hydrogen production via metabolic engineering of fermentative carbon metabolism in a cyanobacterium.
Topics: Acetates; Alanine; Bacterial Proteins; Carbohydrate Dehydrogenases; Carbon; Chromatography, Liquid; Genetic Engineering; Hydrogen; Lactic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Oxidation-Reduction; Pyruvic Acid; Succinic Acid; Synechococcus | 2010 |
Conformation specific and charge directed reactivity of radical cation intermediates of alpha-substituted (amino, hydroxy, and keto) bioactive carboxylic acids.
Topics: Carboxylic Acids; Cations; Glycine; Hydrogen Bonding; Lactic Acid; Models, Theoretical; Pyruvic Acid; Valine | 2010 |
Effects of hypothermia and cerebral ischemia on cold-inducible RNA-binding protein mRNA expression in rat brain.
Topics: Analysis of Variance; Animals; Brain; Cold Temperature; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Hypothermia; Hypoxia-Ischemia, Brain; Lactic Acid; Male; Phosphofructokinase-1; Pyruvic Acid; Rats; Rats, Wistar; RNA-Binding Proteins; RNA, Messenger; Statistics as Topic | 2010 |
Elucidating mechanisms of solvent toxicity in ethanologenic Escherichia coli.
Topics: Acetic Acid; Adenosine Triphosphate; Alcohol Dehydrogenase; Biomass; Escherichia coli; Escherichia coli Proteins; Ethanol; Lactic Acid; Pyruvate Decarboxylase; Pyruvic Acid; Solvents | 2010 |
Cardiac contractile dysfunction during acute hyperglycemia due to impairment of SERCA by polyol pathway-mediated oxidative stress.
Topics: Acute Disease; Aldehyde Reductase; Animals; Calcium Signaling; Glucose; Glutathione; Heart; Hyperglycemia; In Vitro Techniques; Lactic Acid; Male; Myocardial Contraction; Myocardium; Oxidation-Reduction; Oxidative Stress; Perfusion; Peroxynitrous Acid; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Superoxides; Tyrosine | 2010 |
Cerebral dynamics and metabolism of hyperpolarized [1-(13)C]pyruvate using time-resolved MR spectroscopic imaging.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Carbon Isotopes; Lactic Acid; Magnetic Resonance Imaging; Male; Models, Biological; Pyruvic Acid; Rats; Rats, Wistar | 2010 |
Increased interstitial concentrations of pyruvate and lactate in the trapezius muscle of patients with fibromyalgia: a microdialysis study.
Topics: Adult; Cross-Sectional Studies; Extracellular Fluid; Female; Fibromyalgia; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Muscle, Skeletal; Pain Measurement; Pyruvic Acid; Surveys and Questionnaires | 2010 |
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain.
Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Citric Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Lactic Acid; Male; Models, Biological; Nerve Endings; Pyrithiamine; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes; Thiamine Deficiency | 2010 |
Evidence for compromised metabolic function and limited glucose uptake in spermatozoa from the teratospermic domestic cat (Felis catus) and cheetah (Acinonyx jubatus).
Topics: Acinonyx; Acrosome; Animals; Cats; Energy Metabolism; Glucose; Glycolysis; Lactic Acid; Male; Pyruvic Acid; Semen Analysis; Sperm Motility; Spermatozoa | 2010 |
Both forward and reverse TCA cycles operate in green sulfur bacteria.
Topics: Acetate Kinase; Acetates; Acetyl Coenzyme A; ATP Citrate (pro-S)-Lyase; Autotrophic Processes; Bacterial Proteins; Biomass; Carbon; Carbon Isotopes; Chlorobi; Citric Acid Cycle; Coenzyme A Ligases; Gene Expression Regulation, Bacterial; Lactic Acid; Metabolic Networks and Pathways; Models, Biological; Molecular Structure; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Effects of malate, lactate, and pyruvate on myoglobin redox stability in homogenates of three bovine muscles.
Topics: Animals; Cattle; Color; Food Preservation; Lactic Acid; Malates; Meat; Metmyoglobin; Muscle, Skeletal; Myoglobin; Oxidation-Reduction; Pyruvic Acid | 2010 |
In vivo 13C spectroscopy in the rat brain using hyperpolarized [1-(13)C]pyruvate and [2-(13)C]pyruvate.
Topics: Algorithms; Animals; Bicarbonates; Brain; Carbon Isotopes; Computer Simulation; Isotope Labeling; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Models, Biological; Pyruvic Acid; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley | 2010 |
Testosterone affects hormone-sensitive lipase (HSL) activity and lipid metabolism in the left ventricle.
Topics: Adenine; Animals; Body Weight; Fatty Acids; Glycogen; Heart Ventricles; Lactic Acid; Lipid Metabolism; Male; Organ Size; Phosphates; Pyruvic Acid; Rats; Rats, Wistar; Sterol Esterase; Testosterone | 2010 |
Venous obstruction and cerebral perfusion during experimental cardiopulmonary bypass.
Topics: Animals; Biomarkers; Blood Gas Analysis; Blood Glucose; Brain Ischemia; Cardiopulmonary Bypass; Central Venous Pressure; Cerebrovascular Circulation; Disease Models, Animal; Glycerol; Hypothermia, Induced; Lactic Acid; Microdialysis; Monitoring, Intraoperative; Oxygen; Pyruvic Acid; Regional Blood Flow; Spectroscopy, Near-Infrared; Superior Vena Cava Syndrome; Swine; Vena Cava, Inferior | 2010 |
[Is lactate a good indicator of brain tissue hypoxia in the acute phase of traumatic brain injury? Results of a pilot study in 21 patients].
Topics: Adult; Biomarkers; Brain Injuries; Diagnosis, Differential; Energy Metabolism; Glucose; Humans; Hypoxia, Brain; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Pyruvic Acid; Young Adult | 2010 |
Relevance of cerebral interleukin-6 after aneurysmal subarachnoid hemorrhage.
Topics: Biomarkers; Brain Ischemia; C-Reactive Protein; Critical Care; Encephalitis; Extracellular Fluid; Female; Humans; Interleukin-6; Lactic Acid; Male; Microdialysis; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage | 2010 |
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Brain Chemistry; Cells, Cultured; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Immunohistochemistry; Lactic Acid; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Neurons; Nitrogen; Pyruvic Acid | 2011 |
Partial liver ischemia is followed by metabolic changes in the normally perfused part of the liver during reperfusion.
Topics: Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Glucose; Glycerol; Humans; Ischemia; Lactic Acid; Liver; Liver Neoplasms; Microdialysis; Pyruvic Acid; Reperfusion Injury; Sus scrofa | 2010 |
Brain hypoxanthine concentration correlates to lactate/pyruvate ratio but not intracranial pressure in patients with acute liver failure.
Topics: Adolescent; Adult; Brain; Brain Edema; Female; Humans; Hyperammonemia; Hypoxanthine; Inosine; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Male; Microdialysis; Middle Aged; Pyruvic Acid; Young Adult | 2010 |
Exogenous carbon monoxide does not affect cell membrane energy availability assessed by sarcolemmal calcium fluxes during myocardial ischaemia-reperfusion in the pig.
Topics: Animals; Calcium; Carbon Monoxide; Cell Membrane; Coronary Occlusion; Energy Metabolism; Glucose; Ischemic Preconditioning, Myocardial; Lactic Acid; Microdialysis; Myocardial Reperfusion Injury; Pyruvic Acid; Sarcolemma; Swine | 2011 |
[Efficacy of cytoflavine in treating traumatic toxicosis].
Topics: Animals; Blood Circulation; Blood Pressure; Crush Syndrome; Drug Combinations; Flavin Mononucleotide; Inosine Diphosphate; Lactic Acid; Male; Niacinamide; Oxygen Consumption; Pyruvic Acid; Rats; Respiration; Succinates; Time Factors; Water-Electrolyte Balance | 2010 |
Assessment of metabolic phenotypes in patients with non-ischemic dilated cardiomyopathy undergoing cardiac resynchronization therapy.
Topics: Adenosine Triphosphate; Adult; Aged; Amino Acids; Biomarkers; Blood Glucose; Cardiac Resynchronization Therapy; Cardiomyopathy, Dilated; Energy Metabolism; Fatty Acids, Nonesterified; Female; Heart Failure; Humans; Lactic Acid; Male; Middle Aged; Mitochondria, Heart; Myocardial Contraction; Myocardium; Oxygen; Oxygen Consumption; Phenotype; Prospective Studies; Proteomics; Pyruvic Acid; Stroke Volume; Time Factors; Treatment Failure; Ventricular Function, Left | 2010 |
Imaging tumour cell metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
Topics: Animals; Carbon Isotopes; Humans; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Neoplasms; Pyruvic Acid | 2010 |
Effect of mannitol on brain metabolism and tissue oxygenation in severe haemorrhagic stroke.
Topics: Adult; Blood Pressure; Brain; Diuretics, Osmotic; Female; Glasgow Coma Scale; Glucose; Humans; Intracranial Hemorrhages; Intracranial Pressure; Lactic Acid; Male; Mannitol; Microdialysis; Middle Aged; Oxygen; Pyruvic Acid; Retrospective Studies; Stroke | 2011 |
Responses of Staphylococcus aureus exposed to HCl and organic acid stress.
Topics: Acetic Acid; Acids; Adaptation, Physiological; Ammonia; Citric Acid Cycle; Food Microbiology; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Hydrochloric Acid; Hydrogen-Ion Concentration; Lactic Acid; Oxidative Stress; Pentose Phosphate Pathway; Polymerase Chain Reaction; Pyruvic Acid; Staphylococcus aureus; Stress, Physiological | 2010 |
Differences and similarities in binding of pyruvate and L-lactate in the active site of M4 and H4 isoforms of human lactate dehydrogenase.
Topics: Catalytic Domain; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Models, Molecular; Oxamic Acid; Pyruvic Acid | 2011 |
A new scheme to calculate isotope effects.
Topics: Algorithms; Biocatalysis; Catalytic Domain; Computer Simulation; Hydrogen Bonding; Isotopes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Models, Molecular; NAD; Oxamic Acid; Pyruvic Acid | 2011 |
Metabolic effects of a late hypotensive insult combined with reduced intracranial compliance following traumatic brain injury in the rat.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Disease Models, Animal; Glycerol; Hypotension; Hypoxanthine; Lactic Acid; Male; Pyruvic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 2010 |
The respiratory quotient and blood pyruvate and lactate responses after oral ingestion of glucose and fructose in diabetes mellitus with and without insulin.
Topics: Diabetes Mellitus; Diet; Fructose; Glucose; Humans; Insulin; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid | 1946 |
L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase.
Topics: Carcinoma; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria; Mitochondrial Swelling; NAD; Oxygen; Oxygen Consumption; Prostate; Prostatic Neoplasms; Pyruvic Acid | 2010 |
Lactate-to-pyruvate ratio as a marker of propofol infusion syndrome after subarachnoid hemorrhage.
Topics: Adult; Biomarkers; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lactic Acid; Propofol; Pyruvic Acid; Subarachnoid Hemorrhage; Syndrome | 2011 |
Factors affecting the levels of lactic acid and pyruvic acid in the blood.
Topics: Acidosis; Blood; Humans; Lactic Acid; Pyruvic Acid | 1946 |
Characterization of lactate dehydrogenase enzyme in seminal plasma of Japanese quail (Coturnix coturnix japonica).
Topics: Animals; Coturnix; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Male; NAD; Pyruvic Acid; Semen; Spermatozoa; Urea | 2011 |
Detection of myocardial ischaemia using surface microdialysis on the beating heart.
Topics: Animals; Biomarkers; Disease Models, Animal; Energy Metabolism; Female; Glucose; Glycerol; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardium; Pericardium; Predictive Value of Tests; Pyruvic Acid; Swine; Time Factors | 2011 |
Cerebral glucose metabolism after traumatic brain injury in the rat studied by 13C-glucose and microdialysis.
Topics: Anaerobiosis; Animals; Blood Glucose; Brain Damage, Chronic; Brain Injuries; Carbon Radioisotopes; Energy Metabolism; Extracellular Fluid; Gas Chromatography-Mass Spectrometry; Glycerol; Half-Life; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2011 |
Citrate uptake in exchange with intermediates in the citrate metabolic pathway in Lactococcus lactis IL1403.
Topics: Acetates; Acetoin; Bacterial Proteins; Citric Acid; Glucose; Lactic Acid; Lactococcus lactis; Metabolic Networks and Pathways; Organic Anion Transporters; Pyruvic Acid | 2011 |
Mitochondrial dysfunction in autism.
Topics: Autistic Disorder; Case-Control Studies; Child, Preschool; DNA Copy Number Variations; DNA, Mitochondrial; Female; Gene Deletion; Humans; Hydrogen Peroxide; Lactic Acid; Lymphocytes; Male; Mitochondrial Diseases; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Phosphorylation; Pyruvic Acid | 2010 |
Intracerebral monitoring of silent infarcts after subarachnoid hemorrhage.
Topics: Adult; Asymptomatic Diseases; Brain; Cerebral Infarction; Critical Care; Female; Glucose; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen; Pyruvic Acid; Retrospective Studies; Subarachnoid Hemorrhage; Tomography, X-Ray Computed | 2011 |
New modalities to assess efficacy of triple-h therapy: early experience.
Topics: Blood Pressure; Blood Volume; Cerebrovascular Circulation; Hemodilution; Humans; Hypoxia-Ischemia, Brain; Lactic Acid; Microdialysis; Monitoring, Physiologic; Nervous System Diseases; Prospective Studies; Pyruvic Acid | 2011 |
The influence of glucose concentration and hypoxia on VEGF secretion by cultured retinal cells.
Topics: Animals; Cattle; Cells, Cultured; Endothelium, Vascular; Glucose; Humans; Hypoxia; Lactic Acid; Pyruvic Acid; Retinal Neurons; RNA, Messenger; Up-Regulation; Vascular Endothelial Growth Factor B | 2011 |
Prostacyclin infusion may prevent secondary damage in pericontusional brain tissue.
Topics: Blood Glucose; Brain Concussion; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Epoprostenol; Frontal Lobe; Glutamic Acid; Glycerol; Humans; Image Processing, Computer-Assisted; Infusions, Intravenous; Intracranial Hypertension; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Pyruvic Acid; Skull Base; Skull Fractures; Tomography, X-Ray Computed; Vasodilator Agents | 2011 |
Analytical validation of microdialysis analyzer for monitoring glucose, lactate and pyruvate in cerebral microdialysates.
Topics: Brain; Glucose; Humans; Lactic Acid; Limit of Detection; Microdialysis; Pyruvic Acid; Reproducibility of Results | 2011 |
Alterations in cerebral oxidative metabolism following traumatic brain injury.
Topics: Brain; Brain Injuries; Female; Humans; Lactic Acid; Microdialysis; Oxygen; Pyruvic Acid; Tomography, X-Ray Computed; Wounds, Gunshot; Young Adult | 2011 |
Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Animals, Newborn; Bicuculline; Brain; Bumetanide; Calcium; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ketone Bodies; Lactic Acid; Male; Neurons; Patch-Clamp Techniques; Pyruvic Acid; Rats; Rats, Wistar; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors | 2011 |
Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia.
Topics: Aconitate Hydratase; Animals; Apoptosis; Brain; Calcium; Electron Transport; Ginsenosides; Glucose; Hippocampus; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Lactic Acid; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Swelling; Neuroprotective Agents; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2011 |
Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients.
Topics: Adult; Biomarkers; Brain Injuries; Cerebral Cortex; Extracellular Fluid; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Glucose; Glutamic Acid; Glycerol; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid | 2011 |
Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1- 13C]pyruvate and 13C magnetic resonance spectroscopic imaging.
Topics: Animals; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Contrast Media; Glioma; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neoplasm Transplantation; Pyruvic Acid; Radionuclide Imaging; Rats; Rats, Wistar | 2011 |
Glucose metabolism in mouse cumulus cells prevents oocyte aging by maintaining both energy supply and the intracellular redox potential.
Topics: Animals; Cellular Senescence; Coumaric Acids; Cumulus Cells; Energy Metabolism; Female; Glucose; Lactic Acid; Mice; Oocytes; Organic Chemicals; Oxidation-Reduction; Pyruvic Acid; Rotenone | 2011 |
High brain lactate is not caused by a shift in the lactate dehydrogenase A/B ratio.
Topics: Aging; Animals; Biomarkers; Brain; Cytosol; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Mice; Oxidation-Reduction; Pyruvic Acid | 2011 |
Participation of the liver gluconeogenesis in the glibenclamide-induced hypoglycaemia in rats.
Topics: Animals; Gluconeogenesis; Glucose; Glyburide; Humans; Hypoglycemia; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2011 |
Application of double spin echo spiral chemical shift imaging to rapid metabolic mapping of hyperpolarized [1-¹³C]-pyruvate.
Topics: Alanine; Animals; Bicarbonates; Carbon Radioisotopes; Image Processing, Computer-Assisted; Kidney; Lactic Acid; Magnetic Resonance Imaging; Phantoms, Imaging; Pyruvic Acid; Rats; Software; Tritium | 2011 |
Synechococcus sp. strain PCC 7002 nifJ mutant lacking pyruvate:ferredoxin oxidoreductase.
Topics: Acetates; Darkness; Fermentation; Gene Knockout Techniques; Hydrogen; Lactic Acid; Light; NAD; Oxidation-Reduction; Pyruvate Synthase; Pyruvic Acid; Synechococcus | 2011 |
Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Topics: Antineoplastic Agents; Cell Cycle; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Glucose; Humans; Indoles; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Models, Molecular; NAD; Pyruvic Acid; Structure-Activity Relationship; Substrate Specificity | 2011 |
Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: a review of available literature.
Topics: Aerobiosis; Anaerobiosis; Blood Glucose; Brain; Brain Injuries; Critical Care; Energy Metabolism; Extracellular Fluid; Glutamic Acid; Glycerol; Humans; Hypoxia-Ischemia, Brain; Lactic Acid; Microdialysis; Monitoring, Physiologic; Oxidation-Reduction; Oxygen; Pyruvic Acid; Regional Blood Flow | 2011 |
Estimation of intracellular fluxes in cerebellar neurons after hypoglycemia: importance of the pyruvate recycling pathway and glutamine oxidation.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Glucose; Glutamic Acid; Glutamine; Glycolysis; Hypoglycemia; Intracellular Fluid; Lactic Acid; Mice; Neural Pathways; Neurons; Oxidation-Reduction; Pyruvic Acid | 2011 |
Effects of pyruvate, succinate, and lactate enhancement on beef longissimus raw color.
Topics: Animals; Cattle; Food Handling; Food Packaging; Food Preservatives; Hydrogen-Ion Concentration; Lactic Acid; Meat; Metmyoglobin; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Oxygen; Pigmentation; Pyruvic Acid; Succinic Acid; Surface Properties; Thiobarbituric Acid Reactive Substances; Time Factors; Vacuum | 2011 |
Dynamic modeling of lactic acid fermentation metabolism with Lactococcus lactis.
Topics: Chromatography, Liquid; Computer Simulation; Fermentation; Fructosediphosphates; Glucose-6-Phosphate; L-Lactate Dehydrogenase; Lactic Acid; Lactococcus lactis; Monosaccharide Transport Proteins; Phosphoenolpyruvate; Pyruvate Kinase; Pyruvic Acid; Tandem Mass Spectrometry; Time Factors | 2011 |
Striatal energetic homeostasis under anaesthetic conditions.
Topics: Animals; Blood Glucose; Body Temperature; Corpus Striatum; Electroencephalography; Electrophysiology; Glucose; Heart Rate; Homeostasis; Hypnotics and Sedatives; Ketamine; Lactic Acid; Male; Microdialysis; Pentobarbital; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Respiration | 2011 |
In vivo regulation of alcohol dehydrogenase and lactate dehydrogenase in Rhizopus oryzae to improve L-lactic acid fermentation.
Topics: Alcohol Dehydrogenase; Culture Media; Disulfides; Enzyme Inhibitors; Ethanol; Ethylmaleimide; Fermentation; Glucose; Industrial Microbiology; L-Lactate Dehydrogenase; Lactic Acid; Pyridines; Pyruvic Acid; Rhizopus; Trifluoroethanol | 2011 |
[Effects of carbon source and flooding time on microbial Fe(III) reduction in paddy soils].
Topics: Anaerobiosis; Carbon; Ferric Compounds; Floods; Glucose; Lactic Acid; Oryza; Oxidation-Reduction; Pyruvic Acid; Soil; Soil Microbiology | 2010 |
Intraperitoneal glycerol levels and lactate/pyruvate ratio: early markers of postoperative complications.
Topics: Abdomen; Adult; Aged; Aged, 80 and over; Ascitic Fluid; Biomarkers; Colectomy; Female; Glycerol; Humans; Ileostomy; Lactic Acid; Male; Middle Aged; Peritoneal Cavity; Postoperative Complications; Pyruvic Acid; Statistics, Nonparametric; Subcutaneous Tissue; Young Adult | 2011 |
Analysis of the changes in the oxidation of brain tissue cytochrome-c-oxidase in traumatic brain injury patients during hypercapnoea: a broadband NIRS study.
Topics: Adult; Brain; Brain Injuries; Electron Transport Complex IV; Female; Humans; Hypercapnia; Lactic Acid; Male; Middle Aged; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Ultrasonography, Doppler; Young Adult | 2011 |
Beneficial effect of pyruvate therapy on Leigh syndrome due to a novel mutation in PDH E1α gene.
Topics: Alanine; Cells, Cultured; Child, Preschool; Dichloroacetic Acid; Electroencephalography; Fibroblasts; Humans; Lactic Acid; Leigh Disease; Male; Mutation; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Statistics, Nonparametric | 2012 |
Impaired gluconeogenesis in a porcine model of paracetamol induced acute liver failure.
Topics: Acetaminophen; Amino Acids; Animals; Biomarkers; Citric Acid Cycle; Disease Models, Animal; Gluconeogenesis; Glycolysis; Lactic Acid; Liver; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Pyruvic Acid; Swine; Time Factors | 2011 |
Relation between brain interstitial and systemic glucose concentrations after subarachnoid hemorrhage.
Topics: Aged; Blood Glucose; Brain; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Subarachnoid Hemorrhage | 2011 |
Brain substrate utilization during prolonged exercise.
Topics: Adaptation, Physiological; Adult; Blood Glucose; Brain; Exercise Test; Glycerol; Humans; Ketone Bodies; Lactic Acid; Male; Physical Exertion; Pyruvic Acid | 1972 |
Global cerebral edema and brain metabolism after subarachnoid hemorrhage.
Topics: Brain; Brain Edema; Female; Glucose; Humans; Lactic Acid; Middle Aged; Oxygen; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage | 2011 |
Time course of recovery from cerebral vulnerability after severe traumatic brain injury: a microdialysis study.
Topics: Analysis of Variance; Biomarkers; Body Temperature; Brain Injuries; Extracellular Fluid; Female; Glasgow Coma Scale; Glucose; Glutamic Acid; Glycerol; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Time Factors | 2011 |
Parieto-occipital lobe epilepsy caused by a POLG1 compound heterozygous A467T/W748S genotype.
Topics: Adolescent; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Electroencephalography; Epilepsies, Partial; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Mutation; Parietal Lobe; Pyruvic Acid; Sodium Channel Blockers | 2011 |
Lower extracellular glucose level prolonged in elderly patients with severe traumatic brain injury: a microdialysis study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Blood Glucose; Brain; Brain Chemistry; Brain Injuries; Extracellular Fluid; Female; Geriatric Assessment; Glasgow Coma Scale; Glasgow Outcome Scale; Glucose; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Recovery of Function; Severity of Illness Index; Time Factors | 2011 |
Kinetic characterisation of recombinant Corynebacterium glutamicum NAD+-dependent LDH over-expressed in E. coli and its rescue of an lldD- phenotype in C. glutamicum: the issue of reversibility re-examined.
Topics: Bacterial Proteins; Cloning, Molecular; Corynebacterium glutamicum; Enzyme Activation; Escherichia coli; Fructosediphosphates; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Mutation; NAD; Open Reading Frames; Oxidation-Reduction; Pyruvic Acid; Recombinant Proteins | 2011 |
Free [NADH]/[NAD(+)] regulates sirtuin expression.
Topics: Animals; Cells, Cultured; Drosophila melanogaster; Ethanol; Fibroblasts; Gene Expression Regulation; Lactic Acid; Male; Mice; NAD; NIH 3T3 Cells; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Pyruvic Acid; Rats; Rats, Wistar; RNA, Messenger; Sirtuins; Trans-Activators; Transcription Factors | 2011 |
Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Dacarbazine; Drug Monitoring; Glioblastoma; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Neoplasm Transplantation; Pyruvic Acid; Rats; Temozolomide; Treatment Outcome | 2011 |
Multi-band frequency encoding method for metabolic imaging with hyperpolarized [1-(13)C]pyruvate.
Topics: Alanine; Algorithms; Animals; Carbon Isotopes; Computer Simulation; Image Processing, Computer-Assisted; Kidney; Lactic Acid; Liver; Magnetic Resonance Imaging; Male; Metabolism; Mice; Mice, Transgenic; Phantoms, Imaging; Prostatic Neoplasms; Pyruvic Acid | 2011 |
Kinetic modeling of hyperpolarized 13C label exchange between pyruvate and lactate in tumor cells.
Topics: Carbon Isotopes; Cell Line, Tumor; Humans; Kinetics; Lactic Acid; Models, Biological; Neoplasms; Pyruvic Acid | 2011 |
Measurement of intraperitoneal metabolites during hypothermic cardiopulmonary bypass using microdialysis.
Topics: Aged; Ascitic Fluid; Blood Glucose; Cardiopulmonary Bypass; Female; Glycerol; Humans; Hypothermia, Induced; Lactic Acid; Male; Microdialysis; Middle Aged; Postoperative Complications; Prospective Studies; Pyruvic Acid | 2011 |
Impact of high pyruvate concentration on kinetics of rabbit muscle lactate dehydrogenase.
Topics: Animals; Feedback, Physiological; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Muscles; NAD; Pyruvic Acid; Rabbits; Software; Spectrophotometry | 2011 |
Effects of lisuride hydrogen maleate on pericontusional tissue metabolism, brain edema formation, and contusion volume development after experimental traumatic brain injury in rats.
Topics: Animals; Brain Edema; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glutamic Acid; Lactic Acid; Lisuride; Male; Microdialysis; Neuroprotective Agents; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2011 |
Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells cultured in vitro.
Topics: Alanine; Animals; Biological Transport; Cells, Cultured; Dihydrotestosterone; Energy Metabolism; Estradiol; Gene Expression Regulation; Glucose; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Monocarboxylic Acid Transporters; Muscle Proteins; Pyruvic Acid; Rats; Rats, Wistar; RNA, Messenger; Sertoli Cells | 2012 |
In vivo MRSI of hyperpolarized [1-(13)C]pyruvate metabolism in rat hepatocellular carcinoma.
Topics: Alanine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lactic Acid; Liver Neoplasms; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Transpulmonary pyruvate kinetics.
Topics: Adrenergic Agonists; Analysis of Variance; Animals; Blotting, Western; Capillaries; Carbon Isotopes; Cardiac Output; Energy Metabolism; Epinephrine; Female; Indicator Dilution Techniques; Infusions, Intravenous; Kinetics; Lactic Acid; Lung; Monocarboxylic Acid Transporters; Muscle Proteins; Pulmonary Circulation; Pyruvic Acid; Rats; Rats, Wistar; Symporters | 2011 |
A positive fluid balance does not deteriorate tissue metabolism during fluid resuscitation of sepsis.
Topics: Animals; Blood Glucose; Crystalloid Solutions; Escherichia coli Infections; Fluid Therapy; Glycerol; Hypovolemia; Isotonic Solutions; Lactic Acid; Microdialysis; Plasma Substitutes; Pyruvic Acid; Resuscitation; Sepsis; Swine; Water-Electrolyte Balance | 2011 |
Using microdialysis for early detection of vascular thrombosis after kidney transplantation in an experimental porcine model.
Topics: Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Blood Glucose; Disease Models, Animal; Early Diagnosis; Glutamic Acid; Glycerol; Graft Rejection; History, 19th Century; Immunohistochemistry; Kidney Transplantation; Lactic Acid; Microdialysis; Pyruvic Acid; Random Allocation; Reference Values; Sensitivity and Specificity; Sus scrofa; Swine; Thrombosis | 2012 |
Microdialysis detection of lactate in subcutaneous tissue as a reliable indicator of tissue metabolic disorders in an animal sepsis model.
Topics: Animals; Blood Gas Analysis; Disease Models, Animal; Lactic Acid; Lipopolysaccharides; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Wistar; Shock, Septic; Subcutaneous Tissue | 2011 |
Photoperiodic regulation of glycogen metabolism, glycolysis, and glutamine synthesis in tanycytes of the Siberian hamster suggests novel roles of tanycytes in hypothalamic function.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Carbohydrate Metabolism; Cloning, Molecular; Cricetinae; DNA, Complementary; Ependyma; Glucose; Glutamic Acid; Glutamine; Glycogen; Glycolysis; Hypothalamus; In Situ Hybridization; Lactic Acid; Male; Microscopy, Electron; Neuropil; Phodopus; Photoperiod; Pyruvic Acid | 2011 |
Hemoglobin vesicle improves recovery of cardiac function after ischemia-reperfusion by attenuating oxidative stress in isolated rat hearts.
Topics: Animals; Blood Substitutes; Catalase; Coronary Circulation; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Heart; Heart Rate; In Vitro Techniques; Lactic Acid; Male; Myocardium; NG-Nitroarginine Methyl Ester; Oxidation-Reduction; Oxidative Stress; Perfusion; Proteins; Pyruvic Acid; Rats; Rats, Wistar; Reperfusion Injury; Sulfhydryl Compounds; Superoxide Dismutase; Unilamellar Liposomes; Ventricular Dysfunction, Left | 2011 |
Regulation of lactate production in Streptococcus bovis: A spiraling effect that contributes to rumen acidosis.
Topics: Acetyltransferases; Acidosis; Animals; Cattle; Cattle Diseases; Enzyme Activation; Enzyme Inhibitors; Fructosediphosphates; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Magnesium; Phosphates; Pyruvic Acid; Rumen; Streptococcus bovis | 1985 |
Assessing neuronal bioenergetic status.
Topics: Adenosine Triphosphate; Animals; Brain; Cell Extracts; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Embryo, Mammalian; Energy Metabolism; Female; Galactose; Glucose; Humans; L-Lactate Dehydrogenase; Lactic Acid; Neurons; Pregnancy; Pyruvic Acid; Rats | 2011 |
Effects of pyruvate dose on in vivo metabolism and quantification of hyperpolarized ¹³C spectra.
Topics: Alanine; Algorithms; Animals; Bicarbonates; Carbon Isotopes; Cells; Dose-Response Relationship, Drug; Lactic Acid; Magnetic Resonance Imaging; Male; Myocardium; Phantoms, Imaging; Pyruvic Acid; Rats; Rats, Wistar; Software; Time Factors | 2012 |
End-product induced metabolic shifts in Clostridium thermocellum ATCC 27405.
Topics: Acetates; Biomass; Clostridium thermocellum; Culture Media; Enzymes; Fermentation; Formates; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Hydrogen; Lactic Acid; Pyruvic Acid | 2011 |
In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1-(13)C]alanine.
Topics: Alanine; Animals; Carbon Isotopes; Image Processing, Computer-Assisted; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Signal-To-Noise Ratio | 2011 |
[Parameters of oxidative stress in patients with gastric cancer].
Topics: Aged; Female; Follow-Up Studies; Humans; Lactic Acid; Male; Malondialdehyde; Middle Aged; Neoplasm Staging; Oxidative Stress; Prognosis; Pyruvic Acid; Retrospective Studies; Severity of Illness Index; Stomach Neoplasms | 2011 |
Diagnostic accuracy of blood and CSF lactate in identifying children with mitochondrial diseases affecting the central nervous system.
Topics: Adolescent; Area Under Curve; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Infant; Lactic Acid; Male; Mitochondrial Diseases; Pyruvic Acid; ROC Curve | 2012 |
Lack of consistent intracranial pressure pulse morphological changes during episodes of microdialysis lactate/pyruvate ratio increase.
Topics: Adult; Algorithms; Cluster Analysis; Female; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Pulse; Pyruvic Acid; Time Factors | 2011 |
Integrating computational methods to retrofit enzymes to synthetic pathways.
Topics: Algorithms; Computational Biology; Computer Simulation; Enzymes; Lactic Acid; Metabolic Engineering; Metabolic Networks and Pathways; Molecular Dynamics Simulation; Protein Binding; Pyruvic Acid; Synthetic Biology; Thermodynamics | 2012 |
Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa.
Topics: Adenosine Triphosphate; Glycolysis; Humans; Lactic Acid; Male; Mitochondria; Phosphorylation; Pyruvic Acid; Sodium Cyanide; Sperm Capacitation; Sperm Motility; Spermatozoa; Tyrosine | 2011 |
Measuring multiple neurochemicals and related metabolites in blood and brain of the rhesus monkey by using dual microdialysis sampling and capillary hydrophilic interaction chromatography-mass spectrometry.
Topics: Acetylcholine; Animals; Blood Chemical Analysis; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macaca mulatta; Mass Spectrometry; Microdialysis; Pyruvic Acid | 2012 |
Pyruvate and lactate metabolism by Shewanella oneidensis MR-1 under fermentation, oxygen limitation, and fumarate respiration conditions.
Topics: Adenosine Triphosphate; Energy Metabolism; Fermentation; Formates; Fumarates; Lactic Acid; Oxygen; Proton-Motive Force; Pyruvic Acid; Shewanella | 2011 |
Do on- and off-pump coronary bypass surgery differently affect perioperative peripheral tissue metabolism?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Biomarkers; Blood Glucose; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Female; Humans; Lactic Acid; Male; Metabolism; Microdialysis; Middle Aged; Muscle, Skeletal; Perioperative Period; Postoperative Period; Pyruvic Acid; Young Adult | 2012 |
Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats.
Topics: Animals; Calcium Carbonate; Disease Models, Animal; Intestinal Diseases; Intestine, Small; Ischemia; Lactic Acid; Ligation; Ornithine; Oxidative Stress; Pyruvic Acid; Random Allocation; Rats; Reperfusion Injury; Time Factors; Treatment Outcome | 2011 |
Genetically encoded fluorescent sensors for intracellular NADH detection.
Topics: Bacterial Proteins; Cell Line; Cytosol; Glucose; Humans; Hydrogen Peroxide; Lactic Acid; Luminescent Proteins; Microscopy, Fluorescence; Mitochondria; NAD; Oxidation-Reduction; Pyruvic Acid | 2011 |
Chronic stress and carbohydrate metabolism: persistent changes and slow return to normalcy in male albino rats.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism; Chronic Disease; Gluconeogenesis; Glucose-6-Phosphatase; Glycogen; Insulin; Lactic Acid; Liver; Liver Glycogen; Male; Organ Size; Pyruvic Acid; Rats; Rats, Wistar; Recovery of Function; Restraint, Physical; Stress, Psychological; Transaminases | 2012 |
Lactate oxidation coupled to iron or electrode reduction by Geobacter sulfurreducens PCA.
Topics: Acetates; Bioelectric Energy Sources; Electricity; Electrodes; Geobacter; Iron; Lactic Acid; Oxidation-Reduction; Pyruvic Acid; Shewanella | 2011 |
Cerebral metabolism after early decompression craniotomy following controlled cortical impact injury in rats.
Topics: Animals; Brain Injuries; Cerebral Cortex; Craniotomy; Decompression, Surgical; Disease Models, Animal; Glucose; Glutamic Acid; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2011 |
Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels.
Topics: Adenosine Triphosphate; Animals; Brain; Energy Metabolism; Fluoroacetates; Glucose; Intracellular Signaling Peptides and Proteins; Lactic Acid; Mice; Mice, Transgenic; Mitochondrial Proton-Translocating ATPases; Neurons; Neuropeptides; Oligomycins; Orexins; Patch-Clamp Techniques; Pyruvic Acid | 2011 |
Enhanced extraction of heavy metals in the two-step process with the mixed culture of Lactobacillus bulgaricus and Streptococcus thermophilus.
Topics: Arsenates; Biodegradation, Environmental; Culture Media; Environmental Restoration and Remediation; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillus; Metals, Heavy; Pyruvic Acid; Streptococcus thermophilus; Wood | 2012 |
Transpulmonary lactate shuttle.
Topics: Adrenergic beta-Agonists; Animals; Carbon Isotopes; Epinephrine; Female; Glucose; Infusions, Intravenous; Lactic Acid; Lung; Models, Animal; Pyruvic Acid; Rats; Rats, Wistar; Stress, Physiological | 2012 |
Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Cell Line; Cell Survival; Citric Acid Cycle; Dose-Response Relationship, Drug; Doxorubicin; Energy Metabolism; Glucose; Glutamine; Glycolysis; Lactic Acid; Mice; Myocytes, Cardiac; Oxidation-Reduction; Pyruvic Acid; Time Factors | 2012 |
Early intraperitoneal metabolic changes and protease activation as indicators of pancreatic fistula after pancreaticoduodenectomy.
Topics: Adult; Aged; Aged, 80 and over; Amylases; Biomarkers; Blood Glucose; Enzyme Activation; Female; Glucose; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Pancreatic Fistula; Pancreaticoduodenectomy; Peptide Hydrolases; Peritoneal Cavity; Postoperative Period; Pyruvic Acid; Time Factors; Trypsinogen | 2012 |
Rat brain slices oxidize glucose at high rates: a (13)C NMR study.
Topics: Acetates; Anesthesia; Anesthetics; Animals; Aspartic Acid; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2011 |
Aquaporin-9 protein is the primary route of hepatocyte glycerol uptake for glycerol gluconeogenesis in mice.
Topics: Animals; Aquaporins; CHO Cells; Cricetinae; Cricetulus; Cryoprotective Agents; Diabetes Mellitus; Gluconeogenesis; Glucose; Glycerol; Hepatocytes; Lactic Acid; Mice; Mice, Knockout; Pyruvic Acid; Receptors, Leptin | 2011 |
Intestinal ischemia measured by intraluminal microdialysis.
Topics: Animals; Colon; Diagnostic Techniques and Procedures; Glucose; Glycerol; Hemodynamics; Ileum; Intestinal Mucosa; Ischemia; Lactic Acid; Male; Microdialysis; Microvilli; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2012 |
Feeding lactate for CHO cell culture processes: impact on culture metabolism and performance.
Topics: Alanine; Animals; Carbon; Carbon Dioxide; Cell Proliferation; CHO Cells; Cricetinae; Culture Media; Energy Metabolism; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Pyruvic Acid; Quaternary Ammonium Compounds | 2012 |
Increased markers of oxidative stress in autistic children of the Sultanate of Oman.
Topics: Biomarkers; Child; Child Development Disorders, Pervasive; Female; Humans; Lactic Acid; Male; Malondialdehyde; Nitric Oxide; Oman; Oxidative Stress; Protein Carbonylation; Pyruvic Acid; Sensitivity and Specificity | 2012 |
Bioluminescence imaging of energy depletion in vascular pathology: patent ductus arteriosus and atherosclerosis.
Topics: Adenosine Triphosphate; Animals; Arteries; Atherosclerosis; Ductus Arteriosus, Patent; Energy Metabolism; Glucose; Glycogen; Humans; Infant; Lactic Acid; Luminescent Measurements; Premature Birth; Pyruvic Acid; Rabbits | 2012 |
Impact of acetaldehyde- and pyruvic acid-bound sulphur dioxide on wine lactic acid bacteria.
Topics: Acetaldehyde; Culture Media; Fermentation; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillaceae; Pyruvic Acid; Sulfur Dioxide; Wine | 2012 |
Cancer: Sacrifice for survival.
Topics: Anaerobiosis; Cell Respiration; Cell Survival; Disease Progression; Glycolysis; Humans; Lactic Acid; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Pyruvate Kinase; Pyruvic Acid; Reactive Oxygen Species | 2011 |
Influence of lactose and lactate on growth and β-galactosidase activity of potential probiotic Propionibacterium acidipropionici.
Topics: beta-Galactosidase; Cheese; Enzyme Activation; Food Microbiology; Lactic Acid; Lactose; Probiotics; Propionibacterium; Pyruvic Acid | 2012 |
Cerebrospinal fluid biochemistry reflects effects of therapeutic hypothermia after cardiac arrest in a porcine model.
Topics: Animals; Body Temperature; Disease Models, Animal; Glucose; Glutamic Acid; Glycerol; Heart Arrest; Hypothermia, Induced; Lactic Acid; Male; Pyruvic Acid; Swine; Swine, Miniature; Treatment Outcome | 2012 |
Different patterns of metabolic cryo-damage in domestic cat (Felis catus) and cheetah (Acinonyx jubatus) spermatozoa.
Topics: Acinonyx; Acrosome; Animals; Cats; Glucose; Lactic Acid; Male; Membrane Potential, Mitochondrial; Pyruvic Acid; Semen Preservation; Sperm Motility; Spermatozoa | 2012 |
On metabolic shift to lactate consumption in fed-batch culture of mammalian cells.
Topics: Animals; Bioreactors; Cell Line, Tumor; Glycolysis; Lactic Acid; Mice; Models, Biological; Proto-Oncogene Proteins c-akt; Pyruvic Acid; Signal Transduction; Tumor Suppressor Protein p53 | 2012 |
Adaptive changes in fatty acid profile of erythrocyte membrane in relation to plasma and red cell metabolic changes in chronic alcoholic men.
Topics: Adult; Alcoholism; Amino Acids; Blood Glucose; Case-Control Studies; Erythrocyte Membrane; Erythrocytes; Humans; Lactic Acid; Lipids; Male; Middle Aged; Mucoproteins; Pyruvic Acid | 2012 |
Surface microdialysis sampling: a new approach described in a liver ischaemia model.
Topics: Animals; Disease Models, Animal; Energy Metabolism; Female; Glucose; Glycerol; Ischemia; Lactic Acid; Liver; Microdialysis; Pyruvic Acid; Reperfusion; Swine; Time Factors | 2012 |
Ca²⁺ signals of astrocytes are modulated by the NAD⁺/NADH redox state.
Topics: Animals; Astrocytes; Benzazepines; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Glucose; Isoquinolines; Lactic Acid; Mice; Mice, Inbred C57BL; NAD; Oxidation-Reduction; Protein Kinase Inhibitors; Pyruvic Acid; Sulfonamides | 2012 |
Brain tissue oxygenation and cerebral perfusion pressure thresholds of ischemia in a standardized pig brain death model.
Topics: Animals; Blood Pressure; Brain; Brain Death; Brain Injuries; Brain Ischemia; Catheterization; Cerebrovascular Circulation; Critical Care; Disease Models, Animal; Female; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Oxygen; Pyruvic Acid; Swine | 2012 |
[Effects of acetoacetate extract of Radix Aconite on hepatic contents of LA, LDH, PA, Gn and ATPase activities in deficient cold model rats].
Topics: Acetoacetates; Adenosine Triphosphatases; Animals; Disease Models, Animal; Diterpenes; Drugs, Chinese Herbal; Energy Metabolism; Female; Glycogen; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; Plant Extracts; Pyruvic Acid; Rats; Rats, Wistar | 2011 |
Early detection of metabolic changes using microdialysis during and after experimental kidney transplantation in a porcine model.
Topics: Animals; Cold Ischemia; Early Diagnosis; Glucose; Glutamic Acid; Glycerol; Graft Survival; Kidney; Kidney Transplantation; Lactic Acid; Microdialysis; Models, Animal; Monitoring, Intraoperative; Pyruvic Acid; Reproducibility of Results; Swine | 2011 |
Metabolism of hyperpolarized [1-¹³C]pyruvate in the isolated perfused rat lung - an ischemia study.
Topics: Animals; Carbon Isotopes; In Vitro Techniques; Ischemia; Isotope Labeling; Lactic Acid; Lung; Magnetic Resonance Spectroscopy; Male; Perfusion; Principal Component Analysis; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion | 2012 |
Simultaneous determination of lactate and pyruvate in human sweat using reversed-phase high-performance liquid chromatography: a noninvasive approach.
Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Exercise; Female; Humans; Lactic Acid; Linear Models; Male; Pyruvic Acid; Reproducibility of Results; Rest; Sensitivity and Specificity; Sweat | 2012 |
3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Survival; Citric Acid; D-Amino-Acid Oxidase; Electrophoresis, Polyacrylamide Gel; Glioblastoma; Glioma; Glycolysis; Humans; Hydrogen Peroxide; Immunoblotting; Lactic Acid; Oxidative Stress; Pyruvates; Pyruvic Acid; Tetrazolium Salts; Thiazoles | 2012 |
Sampling the conformational energy landscape of a hyperthermophilic protein by engineering key substitutions.
Topics: Allosteric Regulation; Amino Acid Motifs; Amino Acid Substitution; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Fructosediphosphates; Hot Temperature; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Protein Conformation; Protein Engineering; Pyruvic Acid; Thermodynamics; Thermus thermophilus | 2012 |
Integrating flux balance analysis into kinetic models to decipher the dynamic metabolism of Shewanella oneidensis MR-1.
Topics: Acetates; Carbon Isotopes; Citric Acid Cycle; Gluconeogenesis; Glutamic Acid; Glyoxylates; Kinetics; Lactic Acid; Metabolic Networks and Pathways; Models, Biological; Pentose Phosphate Pathway; Pyruvic Acid; Shewanella; Systems Biology | 2012 |
Pressure reactivity index correlates with metabolic dysfunction in a porcine model of intracerebral hemorrhage.
Topics: Animals; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; Glucose; Glutamic Acid; Homeostasis; Intracranial Pressure; Lactic Acid; Metabolic Diseases; Oxygen; Pyruvic Acid; Statistics as Topic; Swine | 2012 |
Characterization of Streptococcus oligofermentans sucrose metabolism demonstrates reduced pyruvic and lactic acid production.
Topics: L-Lactate Dehydrogenase; Lactic Acid; Pyruvic Acid; Streptococcus; Sucrose | 2011 |
Relative catalytic efficiency of ldhL- and ldhD-encoded products is crucial for optical purity of lactic acid produced by lactobacillus strains.
Topics: L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Lactobacillus; Optical Rotation; Pyruvic Acid | 2012 |
Altered fermentative metabolism in Chlamydomonas reinhardtii mutants lacking pyruvate formate lyase and both pyruvate formate lyase and alcohol dehydrogenase.
Topics: Acetyltransferases; Alcohol Dehydrogenase; Chlamydomonas reinhardtii; Ethanol; Fermentation; Formates; Gas Chromatography-Mass Spectrometry; Hydrogen; Lactic Acid; Molecular Sequence Data; Mutagenesis, Insertional; Oxidation-Reduction; Pyruvic Acid | 2012 |
Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antipsychotic Agents; Apoptosis; Aripiprazole; Carbon; Cell Survival; Clozapine; Dihydrolipoamide Dehydrogenase; Dose-Response Relationship, Drug; Electron Transport Complex IV; Extracellular Fluid; Gene Expression Regulation, Enzymologic; Glucose; Glycolysis; Hypoxanthine Phosphoribosyltransferase; Isocitrate Dehydrogenase; Ketone Oxidoreductases; Lactic Acid; Membrane Potential, Mitochondrial; NAD; Oxidoreductases; PC12 Cells; Piperazines; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Quinolones; Rats; RNA, Messenger; Time Factors | 2012 |
A method for simultaneous echo planar imaging of hyperpolarized ¹³C pyruvate and ¹³C lactate.
Topics: Animals; Carbon Isotopes; Cell Line, Tumor; Echo-Planar Imaging; Lactic Acid; Male; Mice; Mice, Transgenic; Prostatic Neoplasms; Pyruvic Acid; Tissue Distribution | 2012 |
Effects of lactate on the early visual cortex of non-human primates, investigated by pharmaco-MRI and neurochemical analysis.
Topics: Aging; Animals; Brain Chemistry; Cerebrovascular Circulation; Data Interpretation, Statistical; Electrophysiological Phenomena; Female; Image Processing, Computer-Assisted; Lactic Acid; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Oxygen; Pyruvic Acid; Vasodilation; Visual Cortex | 2012 |
A role for the Warburg effect in preimplantation embryo development: metabolic modification to support rapid cell proliferation.
Topics: Adenosine Triphosphate; Animals; Cell Proliferation; Citric Acid Cycle; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Glucose; Glycolysis; Humans; Lactic Acid; Oxidative Phosphorylation; Pregnancy; Pyruvic Acid | 2012 |
Comparison of kinetic models for analysis of pyruvate-to-lactate exchange by hyperpolarized 13 C NMR.
Topics: Carbon Isotopes; Cell Line, Tumor; Humans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Biological; Pyruvic Acid | 2012 |
Influence of dichloroacetate (DCA) on lactate production and oxygen consumption in neuroblastoma cells: is DCA a suitable drug for neuroblastoma therapy?
Topics: Acetyl Coenzyme A; Apoptosis; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Culture Media; Dichloroacetic Acid; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Lactic Acid; Mitochondria; Neuroblastoma; Oxidative Phosphorylation; Oxygen; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reactive Oxygen Species | 2012 |
Microdialysis: characterisation of haematomas in myocutaneous flaps by use of biochemical agents.
Topics: Animals; Biomarkers; Catheters, Indwelling; Central Venous Catheters; Female; Glucose; Glycerol; Hematoma; Ischemia; Lactic Acid; Microdialysis; Monitoring, Physiologic; Muscle, Skeletal; Pyruvic Acid; Random Allocation; Rectus Abdominis; Sensitivity and Specificity; Skin Transplantation; Surgical Flaps; Swine; Time Factors | 2013 |
Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise.
Topics: Animals; Blood Glucose; Doxycycline; Female; Hyperinsulinism; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lactic Acid; Male; Mice; Mice, Transgenic; Monocarboxylic Acid Transporters; Physical Conditioning, Animal; Pyruvic Acid; Symporters | 2012 |
Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation.
Topics: Adult; Blood Pressure; Brain; Brain Diseases, Metabolic; Brain Injuries; Cardiopulmonary Resuscitation; Critical Illness; Female; Glucose; Glutamic Acid; Glycerol; Heart Rate; Humans; Incidence; Lactic Acid; Male; Microdialysis; Middle Aged; Oximetry; Predictive Value of Tests; Pyruvic Acid | 2012 |
Lactate/pyruvate ratio as a marker of tissue hypoxia in circulatory and septic shock.
Topics: Aerobiosis; Aged; APACHE; Biomarkers; Female; Humans; Hypoxia; Lactic Acid; Male; Middle Aged; Pyruvic Acid; Quality Control; Shock, Cardiogenic; Shock, Septic; Survival | 2012 |
Glucose and fat oxidation: bomb calorimeter be damned.
Topics: Adenosine Triphosphate; Calorimetry, Indirect; Energy Metabolism; Entropy; Fats; Glucose; Glycolysis; Lactic Acid; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid | 2012 |
Building up a sweat for easier clinical testing.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Humans; Lactic Acid; Pyruvic Acid; Sweat | 2012 |
Blood flow in endogenous and transplanted pancreatic islets in anesthetized rats: effects of lactate and pyruvate.
Topics: Animals; Blood Glucose; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Male; Mesentery; Microspheres; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Inbred WF; Regional Blood Flow; Symporters; Up-Regulation | 2012 |
Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cell Respiration; Citric Acid Cycle; Energy Metabolism; Glycolysis; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lactic Acid; Metabolic Networks and Pathways; Metabolomics; Microfluidic Analytical Techniques; Mitochondrial Proteins; Neoplasm Proteins; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Pentose Phosphate Pathway; Pyruvic Acid | 2012 |
Saturation-recovery metabolic-exchange rate imaging with hyperpolarized [1-13C] pyruvate using spectral-spatial excitation.
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Cell Line, Tumor; Female; Lactic Acid; Magnetic Resonance Spectroscopy; Metabolic Clearance Rate; Neoplasms, Experimental; Protons; Pyruvic Acid; Radiopharmaceuticals; Rats; Rats, Inbred F344 | 2013 |
Role of hyperglycemia-mediated erythrocyte redox state alteration in the development of diabetic retinopathy.
Topics: Blood Glucose; Blood Pressure; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Erythrocyte Membrane; Erythrocytes; Female; Fluorescein Angiography; Glucose Tolerance Test; Glutathione; Glycated Hemoglobin; Humans; Hyperglycemia; Lactic Acid; Male; Middle Aged; NAD; NADP; Oxidation-Reduction; Pyruvic Acid | 2013 |
l-Lactate metabolism in HEP G2 cell mitochondria due to the l-lactate dehydrogenase determines the occurrence of the lactate/pyruvate shuttle and the appearance of oxaloacetate, malate and citrate outside mitochondria.
Topics: Citric Acid; Hep G2 Cells; Humans; L-Lactate Dehydrogenase; Lactic Acid; Malates; Mitochondria; Oxaloacetic Acid; Pyruvic Acid | 2012 |
Variable carbon catabolism among Salmonella enterica serovar Typhi isolates.
Topics: Carbon; Carboxylic Acids; Cluster Analysis; Glycerol; Glycerophosphates; Lactic Acid; Metabolome; Nucleosides; Phenotype; Pyruvic Acid; Salmonella typhi; Serine | 2012 |
Blood metabolite data in response to maximal exercise in healthy subjects.
Topics: Adult; Ammonia; Biomarkers; Energy Metabolism; Exercise; Exercise Test; Exercise Tolerance; Female; France; Heart Rate; Humans; Lactic Acid; Male; Middle Aged; Mitochondrial Diseases; Muscle Contraction; Muscle, Skeletal; Muscular Diseases; Oxygen Consumption; Pyruvic Acid; Recovery of Function; Time Factors | 2012 |
Early detection of subclinical organ dysfunction by microdialysis of the rectus abdominis muscle in a porcine model of critical intra-abdominal hypertension.
Topics: Animals; Disease Models, Animal; Intra-Abdominal Hypertension; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Rectus Abdominis; Swine | 2012 |
The effect of fractionated plasma separation and adsorption on cerebral amino acid metabolism and oxidative metabolism during acute liver failure.
Topics: Adult; Amino Acids; Cerebrum; Dialysis Solutions; Extracorporeal Circulation; Female; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Male; Microdialysis; Middle Aged; Pyruvic Acid; Sorption Detoxification; Statistics, Nonparametric | 2012 |
Changes in cardiac energy metabolic pathways in overweighed rats fed a high-fat diet.
Topics: Acetyl-CoA C-Acyltransferase; Animals; Blotting, Western; Body Weight; Carnitine O-Palmitoyltransferase; Cholesterol; Diet, High-Fat; Energy Metabolism; Enoyl-CoA Hydratase; Fatty Acids; Glyceraldehyde 3-Phosphate; Image Processing, Computer-Assisted; Insulin; Lactic Acid; Leptin; Male; Metabolic Networks and Pathways; Mitochondrial Proteins; Myocardium; Overweight; Oxidative Phosphorylation; Palmitoyl-CoA Hydrolase; Phosphopyruvate Hydratase; Pyruvic Acid; Rats; Rats, Inbred WKY; Triglycerides; Triose-Phosphate Isomerase | 2013 |
Proteomic analysis of Bacillus thuringiensis ΔphaC mutant BMB171/PHB(-1) reveals that the PHB synthetic pathway warrants normal carbon metabolism.
Topics: Acetates; Acyltransferases; Bacillus thuringiensis; Bacterial Proteins; Carbon; Citric Acid; Gene Knockout Techniques; Hydroxybutyrates; Lactic Acid; Metabolic Networks and Pathways; Models, Biological; Organisms, Genetically Modified; Polyesters; Proteome; Proteomics; Pyruvic Acid | 2012 |
'Long' pressure reactivity index (L-PRx) as a measure of autoregulation correlates with outcome in traumatic brain injury patients.
Topics: Adult; Algorithms; Arterial Pressure; Blood Glucose; Brain; Brain Injuries; Disability Evaluation; Female; Glutamic Acid; Homeostasis; Humans; Intracranial Pressure; Lactic Acid; Male; Prognosis; Pyruvic Acid; Retrospective Studies; Survival Rate | 2012 |
Implications for burn shock resuscitation of a new in vivo human vascular microdosing technique (microdialysis) for dermal administration of noradrenaline.
Topics: Administration, Cutaneous; Adult; Burns; Dermis; Dose-Response Relationship, Drug; Female; Glucose; Humans; Lactic Acid; Laser-Doppler Flowmetry; Male; Microcirculation; Microdialysis; Nitroglycerin; Norepinephrine; Pyruvic Acid; Shock; Sympathomimetics; Vasodilator Agents | 2012 |
[Blood glucose, urinary glucose, blood ketone bodies, urine ketone bodies, blood lactic acid, and blood pyruvic acid].
Topics: Blood Glucose; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glycosuria; Humans; Ketone Bodies; Lactic Acid; Pregnancy; Pyruvic Acid | 2012 |
Red blood cell transfusion affects microdialysis-assessed interstitial lactate/pyruvate ratio in critically ill patients with late sepsis.
Topics: Adipose Tissue; Aged; Blood Specimen Collection; Erythrocyte Transfusion; Extracellular Fluid; Female; Humans; Hypoxia; Lactic Acid; Male; Microcirculation; Microdialysis; Middle Aged; Multivariate Analysis; Oxidation-Reduction; Pilot Projects; Point-of-Care Systems; Pyruvic Acid; Retrospective Studies; Sepsis; Shock, Septic; Time Factors | 2012 |
[Plasma metabonomics study of ischemic cerebral apoplexy rats treated with Tongsaimai pellets].
Topics: Animals; Brain Ischemia; Drugs, Chinese Herbal; Fructose; Glyceric Acids; Hydroxyproline; Lactic Acid; Leucine; Male; Malonates; Metabolomics; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Stroke; Taurine; Tryptophan | 2012 |
Presence of bound substrate in lactate dehydrogenase from carp liver.
Topics: Animals; Carps; Chromatography, Gel; Enzyme Stability; L-Lactate Dehydrogenase; Lactic Acid; Liver; Mass Spectrometry; NAD; Pyruvic Acid; UDPglucose 4-Epimerase | 2012 |
Release of a humoral circulating cardioprotective factor by remote ischemic preconditioning is dependent on preserved neural pathways in diabetic patients.
Topics: Aged; Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Hemodynamics; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Male; Middle Aged; Myocardial Reperfusion Injury; Pyruvic Acid; Rabbits | 2012 |
Media composition: energy sources and metabolism.
Topics: Culture Media; Embryo Culture Techniques; Energy Metabolism; Humans; Lactic Acid; Pyruvic Acid; Tissue Survival | 2012 |
The frontal lobe and thalamus have different sensitivities to hypoxia-hypotension after traumatic brain injury: a microdialysis study in rats.
Topics: Animals; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Energy Metabolism; Frontal Lobe; Glucose; Glutamic Acid; Glycerol; Hypotension; Hypoxia; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Renal Dialysis; Thalamus | 2012 |
Normobaric hyperoxia does not change optical scattering or pathlength but does increase oxidised cytochrome C oxidase concentration in patients with brain injury.
Topics: Adult; Aged; Brain Injuries; Cerebrovascular Circulation; Electron Transport Complex IV; Female; Hemoglobins; Humans; Hyperoxia; Lactic Acid; Male; Middle Aged; Monitoring, Physiologic; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Pyruvic Acid; Spectroscopy, Near-Infrared; Young Adult | 2013 |
The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer.
Topics: Adult; Aged; Aged, 80 and over; Caveolin 1; Cell Communication; Cell Proliferation; Fibroblasts; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Male; Middle Aged; Monocarboxylic Acid Transporters; Myofibroblasts; Prostatic Neoplasms; Pyruvic Acid; Stromal Cells; Symporters; Thymidine Phosphorylase; Ubiquitin-Protein Ligases | 2012 |
Benzimidazole-based anion receptors exhibiting selectivity for lactate over pyruvate.
Topics: Anions; Benzimidazoles; Crystallography, X-Ray; Hydrogen Bonding; Indoles; Lactic Acid; Models, Molecular; Molecular Structure; Pyruvic Acid; Urea | 2012 |
Glucose is a pH-dependent motor for sperm beat frequency during early activation.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Carbonic Anhydrases; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Energy Metabolism; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Male; Methylamines; Mice; Mitochondria; NAD; NADP; Propionates; Pyruvic Acid; Sperm Motility; Spermatozoa; Succinic Acid | 2012 |
Microarray-based transcriptome of Listeria monocytogenes adapted to sublethal concentrations of acetic acid, lactic acid, and hydrochloric acid.
Topics: Acetic Acid; Adaptation, Physiological; Gene Expression Regulation, Bacterial; Hydrochloric Acid; Hydrogen-Ion Concentration; Lactic Acid; Listeria monocytogenes; Principal Component Analysis; Protein Array Analysis; Pyruvic Acid; Reproducibility of Results; Transcriptome; Virulence | 2012 |
Metabolic master regulators: sharing information among multiple systems.
Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Insulin Resistance; Lactic Acid; Liver; Metabolome; Mitochondria; Models, Biological; Muscles; NAD; NADP; Obesity; Oxidation-Reduction; Pyruvic Acid; Signal Transduction | 2012 |
Deletion of pyruvate decarboxylase by a new method for efficient markerless gene deletions in Gluconobacter oxydans.
Topics: Acetic Acid; DNA, Bacterial; Fructose; Gene Deletion; Genetics, Microbial; Gluconobacter oxydans; Lactic Acid; Mannitol; Molecular Biology; Molecular Sequence Data; Pyruvate Decarboxylase; Pyruvic Acid; Sequence Analysis, DNA | 2013 |
Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells.
Topics: Breast Neoplasms; Butadienes; Cell Line, Tumor; Female; Humans; Lactic Acid; Male; MCF-7 Cells; Mitogen-Activated Protein Kinase Kinases; Nitriles; Prostatic Neoplasms; Pyruvic Acid | 2013 |
Cryotolerance of in vitro-produced porcine blastocysts is improved when using glucose instead of pyruvate and lactate during the first 2 days of embryo culture.
Topics: Age Factors; Animals; Apoptosis; Blastocyst; Cryopreservation; Embryo Culture Techniques; Embryonic Development; Fertilization in Vitro; Glucose; In Situ Nick-End Labeling; Lactic Acid; Pyruvic Acid; Survival Analysis; Swine; Vitrification | 2013 |
Intraluminal intestinal microdialysis detects markers of hypoxia and cell damage in experimental necrotizing enterocolitis.
Topics: Animals; Biomarkers; Colon, Sigmoid; Enterocolitis, Necrotizing; Glucose; Glycerol; Hypoxia; Ileum; Intestinal Mucosa; Ischemia; Lactic Acid; Microdialysis; Pyruvic Acid; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Characterization of the major dehydrogenase related to d-lactic acid synthesis in Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293.
Topics: Biotechnology; Cloning, Molecular; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Leuconostoc; Phylogeny; Proteomics; Pyruvic Acid; Recombinant Proteins; Transcriptome | 2012 |
Cerebral energy metabolism during induced mitochondrial dysfunction.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain Chemistry; Cytoplasm; Energy Metabolism; Female; Glucose; Intracranial Pressure; Lactic Acid; Methyl Ethers; Mitochondrial Diseases; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Sevoflurane; Swine | 2013 |
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes.
Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cell Separation; Cells, Cultured; Cellular Senescence; Cytoplasm; Energy Metabolism; Female; Glutamic Acid; Lactic Acid; Male; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; NAD; Nerve Tissue Proteins; Neurons; Oxidation-Reduction; Primary Cell Culture; Pyruvic Acid; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
The effect of temperature on L-lactic acid production and metabolite distribution of Lactobacillus casei.
Topics: Acetic Acid; Bioreactors; Culture Media; Fermentation; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Lacticaseibacillus casei; Pyruvic Acid; Temperature | 2012 |
Enhancement of acetaminophen-induced chronic hepatotoxicity in restricted fed rats: a nonclinical approach to acetaminophen-induced chronic hepatotoxicity in susceptible patients.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antipyretics; Blood Glucose; Chemical and Drug Induced Liver Injury; Creatine; Creatinine; Diet; Glutathione; Glutathione Disulfide; Lactic Acid; Male; Malnutrition; Nutritional Status; Pyruvic Acid; Rats; Risk Factors; Taurine | 2012 |
Heteroplasmic m.1624C>T mutation of the mitochondrial tRNA(Val) gene in a proband and his mother with repeated consciousness disturbances.
Topics: Adult; Asian People; Cerebrospinal Fluid; Consciousness Disorders; DNA, Mitochondrial; Female; Humans; Lactic Acid; Male; Point Mutation; Pyruvic Acid; RNA, Transfer, Val | 2012 |
Evaluating the effects of extended cold ischemia on interstitial metabolite in grafts in kidney transplantation using microdialysis.
Topics: Animals; Blood Glucose; Cold Ischemia; Energy Metabolism; Glutamic Acid; Glycerol; Graft Survival; Kidney; Kidney Transplantation; Lactic Acid; Microdialysis; Pyruvic Acid; Swine; Warm Ischemia | 2013 |
Analysis of energy generation and glycolysis pathway in diminazene aceturate-resistant Babesia gibsoni isolate in vitro.
Topics: Adenosine Triphosphate; Antiprotozoal Agents; Babesia; Diminazene; Energy Metabolism; Glucose; Glycolysis; L-Lactate Dehydrogenase; Lactic Acid; Pyruvate Kinase; Pyruvic Acid | 2012 |
Severe subacute necrotizing encephalopathy (Leigh-like syndrome) in American Staffordshire bull terrier dogs.
Topics: Animals; Brain Stem; Dog Diseases; Dogs; Lactic Acid; Leigh Disease; Pyruvic Acid | 2013 |
A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates.
Topics: Adenocarcinoma; Algorithms; Animals; Electromagnetic Fields; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolism; Mice; Mice, Transgenic; NAD; Prostatic Neoplasms; Pyruvic Acid; Radio Waves; Tissue Distribution | 2012 |
Separation of carboxylic acids in human serum by isotachophoresis using a commercial field-deployable analytical platform combined with in-house glass microfluidic chips.
Topics: 3-Hydroxybutyric Acid; Carboxylic Acids; Chemistry Techniques, Analytical; Fluorescence; Glass; Humans; Isotachophoresis; Lactic Acid; Microfluidics; Pyruvic Acid; Reference Standards; Serum | 2012 |
Combination of LC-MS- and GC-MS-based metabolomics to study the effect of ozonated autohemotherapy on human blood.
Topics: Adult; Antioxidants; Biomarkers; Blood Cell Count; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Hemolysis; Humans; Lactic Acid; Lysophospholipids; Male; Metabolome; Metabolomics; Oxidation-Reduction; Oxidative Stress; Ozone; Plastics; Polyvinyl Chloride; Pyruvic Acid; Young Adult | 2012 |
Enzymatic pyruvate measurement by Cobas 6000 open channel assay.
Topics: Blood Chemical Analysis; Calibration; Humans; Lactic Acid; Limit of Detection; Point-of-Care Systems; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid; Reproducibility of Results | 2012 |
Assessment of early diabetic renal changes with hyperpolarized [1-(13) C]pyruvate.
Topics: Animals; Bicarbonates; Carbon Isotopes; Diabetes Mellitus, Experimental; Female; Kidney; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Potassium; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Rats; Rats, Wistar; Sodium | 2013 |
Kinetic modeling of hyperpolarized (13)C pyruvate metabolism in tumors using a measured arterial input function.
Topics: Animals; Carbon Isotopes; Cell Line, Tumor; Computer Simulation; Fibrosarcoma; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolic Clearance Rate; Models, Biological; Pyruvic Acid; Radiopharmaceuticals; Rats | 2013 |
Effects of the neurological wake-up test on clinical examination, intracranial pressure, brain metabolism and brain tissue oxygenation in severely brain-injured patients.
Topics: Adult; Brain; Brain Chemistry; Brain Injuries; Deep Sedation; Female; Glucose; Hemodynamics; Humans; Intracranial Pressure; Lactic Acid; Male; Middle Aged; Neurologic Examination; Outcome and Process Assessment, Health Care; Oxygen; Prospective Studies; Pyruvic Acid; Wakefulness | 2012 |
Metabolic effects of three different inotropic strategies in the newborn piglet myocardium.
Topics: Animals; Animals, Newborn; Cardiotonic Agents; Dobutamine; Dopamine; Epinephrine; Hemodynamics; Lactic Acid; Microdialysis; Milrinone; Myocardium; Pyruvic Acid; Swine | 2013 |
Clinical experience with microdialysis catheters in pediatric liver transplants.
Topics: Adolescent; Age Factors; Biomarkers; Blood Glucose; Catheters, Indwelling; Child; Child, Preschool; Early Diagnosis; Feasibility Studies; Female; Glycerol; Graft Rejection; Humans; Infant; Ischemia; Lactic Acid; Liver Transplantation; Male; Microdialysis; Point-of-Care Systems; Predictive Value of Tests; Pyruvic Acid; Sensitivity and Specificity; Time Factors; Treatment Outcome | 2013 |
Cerebrospinal fluid lactate and pyruvate concentrations and their ratio.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Infant; Lactic Acid; Male; Middle Aged; Pyruvic Acid; Reference Values | 2013 |
Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas.
Topics: Carbon Isotopes; Carcinoma, Renal Cell; Cell Line; Cell Line, Tumor; Glycolysis; Humans; Kidney Tubules, Proximal; Lactic Acid; Magnetic Resonance Spectroscopy; Neoplasm Metastasis; Pyruvic Acid | 2013 |
Metabolic flux analysis of genetically engineered Saccharomyces cerevisiae that produces lactate under micro-aerobic conditions.
Topics: Aerobiosis; Genetic Engineering; Lactic Acid; Pentose Phosphate Pathway; Pyruvic Acid; Saccharomyces cerevisiae | 2013 |
Effect of ouabain on metabolic oxidative state in living cardiomyocytes evaluated by time-resolved spectroscopy of endogenous NAD(P)H fluorescence.
Topics: Animals; Cardiotonic Agents; Female; Lactic Acid; Mitochondria; Myocytes, Cardiac; NAD; NADP; Ouabain; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 2012 |
Inhibitory effect of tumor necrosis factor α on gluconeogenesis in perfused rat liver.
Topics: Alanine; Animals; Area Under Curve; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Urea | 2013 |
Metabolomic analysis of cerebrospinal fluid indicates iron deficiency compromises cerebral energy metabolism in the infant monkey.
Topics: Anemia, Iron-Deficiency; Animals; Brain; Citric Acid; Energy Metabolism; Female; Glutamine; Iron Deficiencies; Lactic Acid; Macaca mulatta; Magnetic Resonance Imaging; Metabolomics; Pyruvic Acid | 2013 |
Metabolic signatures of human adipose tissue hypoxia in obesity.
Topics: Adult; Body Mass Index; Cell Hypoxia; Fasting; Female; Forearm; Glucose; Glycolysis; Humans; Lactic Acid; Male; Middle Aged; Muscle, Skeletal; Obesity; Overweight; Oxygen Consumption; Postprandial Period; Pyruvic Acid; Subcutaneous Fat; Young Adult | 2013 |
Metabolic analysis of antibody producing CHO cells in fed-batch production.
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Cell Culture Techniques; CHO Cells; Cricetinae; Cricetulus; Glucose; Isotope Labeling; Lactic Acid; Metabolome; Phosphoenolpyruvate Carboxykinase (ATP); Pyruvic Acid; Recombinant Proteins; Ribose | 2013 |
Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the PI3K/Akt pathway.
Topics: Animals; Brain Edema; Brain Infarction; Chromones; Energy Metabolism; Enzyme Inhibitors; L-Lactate Dehydrogenase; Lactic Acid; Leptin; Male; Mice; Morpholines; Nerve Tissue Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyruvic Acid; Reperfusion Injury; Signal Transduction | 2013 |
Aerobic to anaerobic transition in Biomphalaria glabrata (Say, 1818) infected with different miracidial doses of Echinostoma paraensei (Lie and Basch, 1967) by high-performance liquid chromatography.
Topics: Aerobiosis; Anaerobiosis; Animals; Biomphalaria; Chromatography, High Pressure Liquid; Cricetinae; Disease Vectors; Echinostoma; Glucose; Glycogen; Hemolymph; Histocytochemistry; Host-Parasite Interactions; L-Lactate Dehydrogenase; Lactic Acid; Mesocricetus; Oxalic Acid; Pyruvic Acid; Succinic Acid; Time Factors | 2013 |
Nutrient deprivation induces the Warburg effect through ROS/AMPK-dependent activation of pyruvate dehydrogenase kinase.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Apoptosis; Energy Metabolism; Food Deprivation; Glycolysis; HeLa Cells; Humans; Isotonic Solutions; Lactic Acid; Mutation; Neoplasms; Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Reactive Oxygen Species; Transcriptional Activation | 2013 |
Lactate oxidation in human skeletal muscle mitochondria.
Topics: Cell Respiration; Female; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; NAD; Oxidation-Reduction; Pyruvic Acid | 2013 |
Neural stem/progenitor cells display a low requirement for oxidative metabolism independent of hypoxia inducible factor-1alpha expression.
Topics: 6-Aminonicotinamide; Analysis of Variance; Animals; Bacterial Proteins; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Enzyme Inhibitors; Glucose; Hypoxia-Inducible Factor 1, alpha Subunit; Intermediate Filament Proteins; L-Lactate Dehydrogenase; Lactic Acid; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Electron, Transmission; Mitochondria; Nerve Tissue Proteins; Nestin; Neural Stem Cells; Oxygen; Phosphopyruvate Hydratase; Pyruvic Acid; Sodium Cyanide; Up-Regulation | 2013 |
Quantitative measurement of cancer metabolism using stimulated echo hyperpolarized carbon-13 MRS.
Topics: Alanine; Algorithms; Animals; Biomarkers, Tumor; Carbon Isotopes; Computer Simulation; Lactic Acid; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Models, Biological; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity | 2014 |
Elevated glucose metabolism in the amygdala during an inhibitory avoidance task.
Topics: Amygdala; Animals; Avoidance Learning; Glucose; Glutamic Acid; Glycolysis; Lactic Acid; Male; Memory; Mental Recall; Microdialysis; Oxidation-Reduction; Psychomotor Performance; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2013 |
Nanoparticle-tethered NAD(+) with in situ cofactor regeneration.
Topics: Alcohol Oxidoreductases; Coenzymes; Formate Dehydrogenases; Formates; Lactic Acid; NAD; Nanoparticles; Propylamines; Pyruvic Acid; Silanes; Silicon Dioxide | 2013 |
Intra-peritoneal microdialysis and intra-abdominal pressure after endovascular repair of ruptured aortic aneurysms.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Aortic Aneurysm, Abdominal; Aortic Rupture; Biomarkers; Decompression, Surgical; Early Diagnosis; Endovascular Procedures; Female; Glucose; Glycerol; Humans; Intra-Abdominal Hypertension; Lactic Acid; Male; Microdialysis; Middle Aged; Peritoneal Cavity; Predictive Value of Tests; Pressure; Pyruvic Acid; Time Factors; Treatment Outcome; Urination | 2013 |
Metabolism of glycerol, glucose, and lactate in the citric acid cycle prior to incorporation into hepatic acylglycerols.
Topics: Animals; Citric Acid Cycle; Fasting; Glucose; Glycerides; Glycerol; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Male; Muscle, Skeletal; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2013 |
Investigation of low-molecular weight organic acids and their spatiotemporal variation characteristics in Hongfeng Lake, China.
Topics: China; Lactic Acid; Lakes; Molecular Weight; Organic Chemicals; Oxalic Acid; Pyruvic Acid; Sorbic Acid | 2013 |
Ratiometric analysis in hyperpolarized NMR (I): test of the two-site exchange model and the quantification of reaction rate constants.
Topics: Animals; Cell Line, Tumor; Computer Simulation; Humans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Models, Biological; Neoplasms; Pyruvic Acid; Time Factors; Xenograft Model Antitumor Assays | 2013 |
Embryo development and sex ratio of in vitro-produced porcine embryos are affected by the energy substrate and hyaluronic acid added to the culture medium.
Topics: Animals; Apoptosis; Blastocyst; Culture Media; Embryo Culture Techniques; Embryonic Development; Energy Metabolism; Female; Fertilization in Vitro; Glucose; Hyaluronic Acid; Lactic Acid; Male; Pyruvic Acid; Sex Ratio; Swine; Time Factors | 2014 |
¹H NMR and hyperpolarized ¹³C NMR assays of pyruvate-lactate: a comparative study.
Topics: Carbon Isotopes; Cell Line, Tumor; Humans; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Protons; Pyruvic Acid | 2013 |
Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors.
Topics: Animals; Antimetabolites, Antineoplastic; B-Lymphocytes; Carbon Isotopes; Cell Line, Tumor; Glutaminase; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Lymphoma; Magnetic Resonance Spectroscopy; Male; Mice; Pyruvic Acid; Xenograft Model Antitumor Assays | 2013 |
Is there any association between cerebral vasoconstriction/vasodilatation and microdialysis Lactate to Pyruvate ratio increase?
Topics: Adult; Aged; Algorithms; Brain; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Female; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Models, Biological; Monitoring, Physiologic; Pyruvic Acid; Trauma Severity Indices; Vasoconstriction; Vasodilation | 2013 |
Cerebral microdialysis reflects the neuroprotective effect of fractionated plasma separation and adsorption in acute liver failure better and earlier than intracranial pressure: a controlled study in pigs.
Topics: Ammonia; Animals; Brain Edema; Cerebrum; Extracorporeal Circulation; Glucose; Glutamic Acid; Glutamine; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Microdialysis; Pyruvic Acid; Sorption Detoxification; Swine; Time Factors | 2013 |
A simple three-dimensional-focusing, continuous-flow mixer for the study of fast protein dynamics.
Topics: Anilino Naphthalenesulfonates; Animals; Apoproteins; Enzyme Assays; Equipment Design; Fluorescent Dyes; Horses; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Microfluidic Analytical Techniques; Myoglobin; Protein Unfolding; Pyruvic Acid; Swine | 2013 |
3D CMR mapping of metabolism by hyperpolarized 13C-pyruvate in ischemia-reperfusion.
Topics: Animals; Carbon Isotopes; Disease Models, Animal; Energy Metabolism; Feasibility Studies; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Imaging; Male; Myocardial Reperfusion Injury; Myocardium; Predictive Value of Tests; Pyruvic Acid; Signal-To-Noise Ratio; Swine | 2013 |
Intraparenchymal microdialysis after acute spinal cord injury reveals differential metabolic responses to contusive versus compressive mechanisms of injury.
Topics: Animals; Blood Pressure; Energy Metabolism; Female; Glucose; Heart Rate; Ischemia; Lactic Acid; Microdialysis; Pyruvic Acid; Spinal Cord; Spinal Cord Compression; Spinal Cord Injuries; Swine; Swine, Miniature | 2013 |
Metabolomic profiling analysis reveals chamber-dependent metabolite patterns in the mouse heart.
Topics: Adenine Nucleotides; Amino Acids; Animals; Atrial Function; Blotting, Western; Electrophoresis, Capillary; Energy Metabolism; Fatty Acids; Gene Expression Regulation, Enzymologic; Heart Atria; Heart Ventricles; Lactic Acid; Male; Metabolomics; Mice; Mice, Inbred C57BL; Myocardium; Oxidation-Reduction; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Ventricular Function | 2013 |
Photochemistry of aqueous pyruvic acid.
Topics: Acetic Acid; Acetoin; Aerosols; Atmosphere; Lactic Acid; Light; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Photochemistry; Photolysis; Pyruvic Acid; Water | 2013 |
Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates.
Topics: Adenocarcinoma; Algorithms; Animals; Biotransformation; Carbon Isotopes; Computer Simulation; Image Processing, Computer-Assisted; Indicators and Reagents; Kidney; Lactic Acid; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolism; Mice; Prostatic Neoplasms; Pyruvic Acid; Rats; Urea | 2013 |
Elevated adipose tissue lactate to pyruvate (L/P) ratio predicts poor outcome in critically ill patients with septic shock: a microdialysis study.
Topics: Adipose Tissue; Aged; Critical Illness; Female; Humans; Intensive Care Units; Lactic Acid; Male; Microdialysis; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Prospective Studies; Pyruvic Acid; Shock, Septic | 2013 |
Label-free high-throughput assays to screen and characterize novel lactate dehydrogenase inhibitors.
Topics: Enzyme Assays; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; L-Lactate Dehydrogenase; Lactic Acid; Mass Spectrometry; NAD; Neoplasms; Pyruvic Acid; Spectrometry, Fluorescence | 2013 |
Physical and functional association of lactate dehydrogenase (LDH) with skeletal muscle mitochondria.
Topics: Animals; Biological Transport, Active; Coumaric Acids; L-Lactate Dehydrogenase; Lactic Acid; Mitochondria, Muscle; Mitochondrial Membranes; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2013 |
Differential sensitivities of the growth of Escherichia coli to acrylate under aerobic and anaerobic conditions and its effect on product formation.
Topics: Acetyltransferases; Acrylates; Aerobiosis; Anaerobiosis; Culture Media; Escherichia coli; Glucose; Lactic Acid; Pyruvic Acid | 2013 |
Decline of lactate in tumor tissue after ketogenic diet: in vivo microdialysis study in patients with head and neck cancer.
Topics: Aged; Carcinoma, Squamous Cell; Circadian Rhythm; Diet, Ketogenic; Female; Glucose; Head and Neck Neoplasms; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Reproducibility of Results; Squamous Cell Carcinoma of Head and Neck | 2013 |
Depleted energy charge and increased pulmonary endothelial permeability induced by mitochondrial complex I inhibition are mitigated by coenzyme Q1 in the isolated perfused rat lung.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Blood-Air Barrier; Capillary Permeability; Electron Transport Complex I; Electron Transport Complex III; Endothelium, Vascular; Energy Metabolism; Glycolysis; Lactic Acid; Lung; Lung Injury; Male; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pyridines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion; Rotenone; Ubiquinone; Uncoupling Agents | 2013 |
A patient with congenital hyperlactataemia and Leigh syndrome: an uncommon mitochondrial variant.
Topics: Acidosis, Lactic; DNA, Mitochondrial; Female; Humans; Infant; Lactic Acid; Leigh Disease; Pyruvic Acid; Seizures; Sequence Analysis, DNA | 2013 |
Membrane cut-off does not influence results regarding the measurement of small molecules - a comparative study between 20- and 100-kDa catheters in hepatic microdialysis.
Topics: Animals; Catheters; Equipment Design; Female; Glucose; Glycerol; Hydroxyethyl Starch Derivatives; Lactic Acid; Liver; Membranes, Artificial; Microdialysis; Models, Animal; Molecular Weight; Perfusion; Porosity; Pyruvic Acid; Swine; Time Factors | 2014 |
Energy substrate influences the effect of the timing of the first embryonic cleavage on the development of in vitro-produced porcine embryos in a sex-related manner.
Topics: Animals; Apoptosis; Blastocyst; Cleavage Stage, Ovum; Culture Media; Female; Fertilization in Vitro; Glucose; Lactic Acid; Male; Pyruvic Acid; Swine | 2013 |
Combined administration of hyperbaric oxygen and hydroxocobalamin improves cerebral metabolism after acute cyanide poisoning in rats.
Topics: Animals; Arterial Pressure; Brain; Female; Glucose; Glycerol; Hydroxocobalamin; Hyperbaric Oxygenation; Lactic Acid; Microdialysis; Oxygen; Potassium Cyanide; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2013 |
Roles of HynAB and Ech, the only two hydrogenases found in the model sulfate reducer Desulfovibrio gigas.
Topics: Bacterial Proteins; Desulfovibrio gigas; Fermentation; Gene Deletion; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Hydrogen; Hydrogenase; Lactic Acid; Molecular Sequence Data; Pyruvic Acid; RNA, Bacterial; RNA, Messenger; Transcriptome | 2013 |
A catalyzing phantom for reproducible dynamic conversion of hyperpolarized [1-¹³C]-pyruvate.
Topics: Animals; Carbon Isotopes; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Phantoms, Imaging; Pyruvic Acid | 2013 |
Cellular energetic crisis during human septic shock.
Topics: Adipose Tissue; Female; Humans; Lactic Acid; Male; Pyruvic Acid; Shock, Septic | 2013 |
In vivo magnetic resonance of hyperpolarized [(13)C1]pyruvate: metabolic dynamics in stimulated muscle.
Topics: Alanine; Algorithms; Animals; Carbon Radioisotopes; Electric Stimulation; Female; Glucose Tolerance Test; Insulin; Isotope Labeling; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Muscles; Pyruvic Acid | 2013 |
Cloning and characterization of l-lactate dehydrogenase gene of Staphylococcus aureus.
Topics: Amino Acid Motifs; Cloning, Molecular; Conserved Sequence; DNA, Bacterial; Escherichia coli; Gene Expression; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Molecular Docking Simulation; Molecular Sequence Data; Molecular Weight; Pyruvic Acid; Recombinant Proteins; Sequence Analysis, DNA; Staphylococcus aureus | 2013 |
Live-cell imaging of cytosolic NADH-NAD+ redox state using a genetically encoded fluorescent biosensor.
Topics: Animals; Biosensing Techniques; Calibration; Cell Line, Tumor; Cell Survival; Cytosol; Lactic Acid; Luminescent Proteins; Mice; Molecular Imaging; NAD; Oxidation-Reduction; Protein Engineering; Pyruvic Acid; Single-Cell Analysis | 2014 |
Pyruvate Ringer's solution corrects lactic acidosis and prolongs survival during hemorrhagic shock in rats.
Topics: Acidosis, Lactic; Analysis of Variance; Animals; Arterial Pressure; Carbon Dioxide; Disease Models, Animal; Isotonic Solutions; Lactic Acid; Male; Oxygen; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ringer's Solution; Shock, Hemorrhagic | 2013 |
Detection of urinary metabolomics before and after Pringle maneuver-induced liver ischemia and reperfusion injury in rats using gas chromatography-mass spectrometry.
Topics: Alanine; Alanine Transaminase; Animals; Bilirubin; Gas Chromatography-Mass Spectrometry; Glycerophosphates; Lactic Acid; Liver; Male; Metabolome; Metabolomics; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Serine | 2013 |
Analysis of biochemical changes in rat erythrocytes induced by long-term simvastatin treatment.
Topics: 2,3-Diphosphoglycerate; Animals; Catalase; Erythrocytes; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glycolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactic Acid; Lipid Peroxidation; Male; Pyruvic Acid; Rats; Simvastatin; Superoxide Dismutase | 2013 |
Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Glucose; Glycolysis; Humans; Lactic Acid; Male; NAD; Prostatic Neoplasms; Pyruvic Acid | 2014 |
Early deficits in glycolysis are specific to striatal neurons from a rat model of huntington disease.
Topics: Animals; Cell Respiration; Corpus Striatum; Disease Models, Animal; Extracellular Space; Glucose; Glycolysis; Huntington Disease; Lactic Acid; Male; Neurons; Pyruvic Acid; Rats; Rats, Transgenic | 2013 |
Augmentation of normal and glutamate-impaired neuronal respiratory capacity by exogenous alternative biofuels.
Topics: 3-Hydroxybutyric Acid; Acetylcarnitine; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Respiration; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Glutamic Acid; In Vitro Techniques; Lactic Acid; Mitochondria; Neurons; Nootropic Agents; Oxygen Consumption; Proton Ionophores; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 2013 |
Validation of intraluminal and intraperitoneal microdialysis in ischemic small intestine.
Topics: Aged; Carcinoma; Female; Glucose; Glycerol; Humans; Intestine, Small; Ischemia; Lactic Acid; Male; Mesenteric Arteries; Microdialysis; Middle Aged; Pancreatic Neoplasms; Pancreaticoduodenectomy; Prospective Studies; Pyruvic Acid; Sensitivity and Specificity | 2013 |
Intracellular and extracellular carbonic anhydrases cooperate non-enzymatically to enhance activity of monocarboxylate transporters.
Topics: Animals; Biological Transport; Carbonic Anhydrase II; Carbonic Anhydrase IV; Cytosol; Extracellular Space; Humans; Hydrogen-Ion Concentration; Ketone Bodies; Lactic Acid; Membrane Proteins; Monocarboxylic Acid Transporters; Muscle Proteins; Oocytes; Oxygen Isotopes; Pyruvic Acid; Rats; Symporters; Xenopus | 2014 |
Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain.
Topics: Animals; Brain; Carbon Isotopes; Equipment Design; Equipment Failure Analysis; Feasibility Studies; Female; Humans; Lactic Acid; Macaca fascicularis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity | 2014 |
High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging.
Topics: Alanine; Altitude; Altitude Sickness; Animals; Atmospheric Pressure; Bicarbonates; Blood Glucose; Diabetic Nephropathies; Disease Models, Animal; Female; Humans; Hypoxia; Kidney; Lactic Acid; Magnetic Resonance Imaging; Male; Oxygen; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar | 2014 |
Frequency correction method for improved spatial correlation of hyperpolarized 13C metabolites and anatomy.
Topics: Algorithms; Animals; Artifacts; Carbon Isotopes; Echo-Planar Imaging; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Imaging; Pyruvic Acid; Radiopharmaceuticals; Rats; Rats, Nude; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Tissue Distribution; Urea | 2014 |
Sunlight-initiated chemistry of aqueous pyruvic acid: building complexity in the origin of life.
Topics: Acetoin; Aerosols; Atmosphere; Carbon; Evolution, Chemical; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Spectrophotometry, Ultraviolet; Ultraviolet Rays; Water | 2013 |
Microdialysis monitoring of glucose, lactate, glycerol, and pyruvate in patients with diabetic ketoacidosis.
Topics: Adipose Tissue; Adult; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Extracellular Fluid; Female; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Time Factors; Young Adult | 2013 |
Does tissue ischemia actually contribute to leak after sleeve gastrectomy? An experimental study.
Topics: Anastomotic Leak; Animals; Esophagogastric Junction; Gastrectomy; Glycerol; Lactic Acid; Microdialysis; Pyruvic Acid; Surgical Stapling; Surgical Wound Dehiscence; Swine | 2014 |
Renal cortical pyruvate depletion during AKI.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Gluconeogenesis; Glucose; Glycogen; Hydrogen Peroxide; Ischemia; Kidney Cortex; Kidney Tubules; Lactic Acid; Male; Mice; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reperfusion Injury | 2014 |
Lactate and pyruvate levels in blood and cerebrospinal fluid in patients with Menkes disease.
Topics: Child; Child, Preschool; Humans; Infant; Lactic Acid; Male; Menkes Kinky Hair Syndrome; Pyruvic Acid; Retrospective Studies | 2014 |
Pyruvate-enriched resuscitation: metabolic support of post-ischemic hindlimb muscle in hypovolemic goats.
Topics: Animals; Antioxidants; Citric Acid; Dinoprost; Goats; Hypovolemia; Infusions, Intravenous; Lactic Acid; Lipid Peroxidation; Male; Muscle, Skeletal; Oxidative Stress; Pyruvic Acid; Reactive Nitrogen Species; Reactive Oxygen Species; Reperfusion Injury; Tourniquets | 2014 |
Is higher lactate an indicator of tumor metastatic risk? A pilot MRS study using hyperpolarized (13)C-pyruvate.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Pyruvic Acid; Radiopharmaceuticals; Reproducibility of Results; Risk Factors; Sensitivity and Specificity | 2014 |
Mapping metabolic changes associated with early Radiation Induced Lung Injury post conformal radiotherapy using hyperpolarized ¹³C-pyruvate Magnetic Resonance Spectroscopic Imaging.
Topics: Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Heart; Lactic Acid; Lung; Lung Injury; Male; Oxygen; Pyruvic Acid; Radiation Injuries, Experimental; Radiation Pneumonitis; Radiotherapy, Conformal; Rats; Rats, Sprague-Dawley | 2014 |
The energy-conserving electron transfer system used by Desulfovibrio alaskensis strain G20 during pyruvate fermentation involves reduction of endogenously formed fumarate and cytoplasmic and membrane-bound complexes, Hdr-Flox and Rnf.
Topics: Cell Membrane; Cytoplasm; Desulfovibrio; Electron Transport; Fermentation; Formates; Fumarates; Gene Expression; Lactic Acid; Membrane Transport Proteins; Oxidation-Reduction; Oxidoreductases; Proton Pumps; Pyruvic Acid | 2014 |
Coronary flow reserve is associated with tissue ischemia and is an additive predictor of intensive care unit mortality to traditional risk scores in septic shock.
Topics: Acidosis; Aged; APACHE; Blood Glucose; Coronary Circulation; Echocardiography, Doppler; Echocardiography, Transesophageal; Female; Fractional Flow Reserve, Myocardial; Glycerol; Humans; Intensive Care Units; Kaplan-Meier Estimate; Lactic Acid; Male; Microdialysis; Middle Aged; Myocardial Ischemia; Predictive Value of Tests; Prognosis; Prospective Studies; Pyruvic Acid; Risk Factors; Shock, Septic | 2014 |
Liver, but not muscle, has an entrainable metabolic memory.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Dogs; Energy Metabolism; Female; Glucagon; Glycogen; Glycogen Synthase; Insulin; Lactic Acid; Lipid Metabolism; Liver; Male; Muscle, Skeletal; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid | 2014 |
In vivo single-shot 13C spectroscopic imaging of hyperpolarized metabolites by spatiotemporal encoding.
Topics: Algorithms; Animals; Echo-Planar Imaging; Kidney; Lactic Acid; Lymphoma; Magnetic Resonance Imaging; Male; Mice; Neoplasms; Neoplasms, Experimental; Phantoms, Imaging; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Signal-To-Noise Ratio | 2014 |
Intraperitoneal metabolic consequences of supraceliac aortic balloon occlusion in an experimental animal study using microdialysis.
Topics: Animals; Biomarkers; Disease Models, Animal; Female; Follow-Up Studies; Glucose; Hemodynamics; Lactic Acid; Laser-Doppler Flowmetry; Leriche Syndrome; Male; Mesenteric Vascular Occlusion; Microdialysis; Peritoneum; Pyruvic Acid; Swine | 2014 |
Abdominal hypertension and decompression: the effect on peritoneal metabolism in an experimental porcine study.
Topics: Animals; Blood Pressure; Decompression, Surgical; Disease Models, Animal; Female; Glucose; Hemodynamics; Intra-Abdominal Hypertension; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Swine | 2014 |
Mode of action of cupping--local metabolism and pain thresholds in neck pain patients and healthy subjects.
Topics: Adolescent; Adult; Case-Control Studies; Female; Glucose; Glycerol; Humans; Lactic Acid; Male; Medicine, Traditional; Microdialysis; Middle Aged; Neck Pain; Pain Threshold; Pyruvic Acid; Subcutaneous Tissue; Young Adult | 2014 |
Riboflavin supplementation improves energy metabolism in mice exposed to acute hypoxia.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Carnitine; Dietary Supplements; Drug Evaluation, Preclinical; Energy Metabolism; Fatty Acids, Nonesterified; Hypoxia; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Pyruvic Acid; Random Allocation; Riboflavin; Urea; Vitamin B Complex | 2014 |
Serum 1H-NMR metabolomic fingerprints of acute-on-chronic liver failure in intensive care unit patients with alcoholic cirrhosis.
Topics: Biomarkers; Creatinine; Glutamine; Humans; Intensive Care Units; Ketone Bodies; Lactic Acid; Liver Cirrhosis, Alcoholic; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Metabolome; Multivariate Analysis; Phenylalanine; Pyruvic Acid; Tyrosine | 2014 |
Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells.
Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Line, Tumor; Citric Acid; Gene Expression Regulation, Neoplastic; Gluconates; Glucosamine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; In Vitro Techniques; Lactic Acid; Leupeptins; Lysosomes; Phosphorylation; Proteasome Endopeptidase Complex; Pyruvic Acid; Signal Transduction; Tongue Neoplasms | 2014 |
Acetate kinase isozymes confer robustness in acetate metabolism.
Topics: Acetate Kinase; Acetates; Acetyl Coenzyme A; Base Sequence; Conserved Sequence; Genes, Bacterial; Isoenzymes; Kinetics; Lactic Acid; Lactococcus lactis; Maltose; Molecular Sequence Data; Mutation; Phylogeny; Pyruvic Acid; Sequence Homology, Amino Acid; Species Specificity; Terminator Regions, Genetic; Transcription Initiation Site | 2014 |
Excitotoxicity and metabolic changes in association with infarct progression.
Topics: Adult; Aged; Aged, 80 and over; Brain; Cerebral Infarction; Disease Progression; Female; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Neurotoxins; Pyruvic Acid; Stroke | 2014 |
Purification and characterization of a urea sensitive lactate dehydrogenase from the liver of the African clawed frog, Xenopus laevis.
Topics: Animals; Dehydration; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; NAD; Protein Processing, Post-Translational; Pyruvic Acid; Urea; Xenopus laevis | 2014 |
In vitro model suggests oxidative stress involved in keratoconus disease.
Topics: Arginine; Ascorbic Acid; Cell Differentiation; Cells, Cultured; Collagen Type I; Collagen Type III; Collagen Type IV; Cornea; Corneal Keratocytes; Extracellular Matrix; Fibroblasts; Glutathione; Humans; Keratoconus; Lactic Acid; Malates; Metabolomics; Myofibroblasts; Oxidative Stress; Proteoglycans; Pyruvic Acid; Transforming Growth Factor beta3 | 2014 |
Higher thermostability of l-lactate dehydrogenases is a key factor in decreasing the optical purity of d-lactic acid produced from Lactobacillus coryniformis.
Topics: Bacterial Proteins; Bioreactors; Calorimetry, Differential Scanning; Enzyme Stability; Escherichia coli; Fermentation; Genes, Synthetic; Half-Life; Hot Temperature; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Lactic Acid; Lactobacillus; Optical Rotation; Phylogeny; Protein Denaturation; Pyruvic Acid; Recombinant Fusion Proteins; Ribotyping; Stereoisomerism | 2014 |
Cerebral tau is elevated after aneurysmal subarachnoid haemorrhage and associated with brain metabolic distress and poor functional and cognitive long-term outcome.
Topics: Aged; Biomarkers; Brain; Cognition Disorders; Female; Follow-Up Studies; Glutamic Acid; Humans; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Neuropsychological Tests; Outcome Assessment, Health Care; Oxygen; Pyruvic Acid; Subarachnoid Hemorrhage; tau Proteins | 2015 |
Comparison of energy metabolism in liver grafts from donors after circulatory death and donors after brain death during cold storage and reperfusion.
Topics: Adult; Aged; Brain Death; Cryopreservation; Energy Metabolism; Glycerol; Graft Survival; Heart Arrest; Humans; Ischemia; Lactic Acid; Liver; Liver Transplantation; Middle Aged; Organ Preservation; Pyruvic Acid; Reperfusion Injury; Time Factors | 2014 |
Changes in glutamate concentration, glucose metabolism, and cerebral blood flow during focal brain cooling of the epileptogenic cortex in humans.
Topics: Adolescent; Adult; Blood Glucose; Brain; Cerebral Cortex; Electroencephalography; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Glutamic Acid; Glycerol; Hippocampus; Humans; Hypothermia, Induced; Lactic Acid; Male; Middle Aged; Preoperative Care; Pyruvic Acid; Regional Blood Flow; Rewarming; Signal Processing, Computer-Assisted; Young Adult | 2014 |
Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage.
Topics: Aged; Biomarkers; Brain Ischemia; Energy Metabolism; Female; Glucose; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Mitochondria; Pyruvic Acid; Subarachnoid Hemorrhage | 2014 |
Efficacy of pyruvate therapy in patients with mitochondrial disease: a semi-quantitative clinical evaluation study.
Topics: Child; Drug Administration Schedule; Female; Glycolysis; Humans; Infant; Lactic Acid; Male; Mitochondrial Diseases; Pyruvic Acid; Treatment Outcome | 2014 |
Sydnone SYD-1 affects the metabolic functions of isolated rat hepatocytes.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Hepatocytes; Lactic Acid; Male; Oxadiazoles; Pyruvic Acid; Rats; Rats, Wistar | 2014 |
HIF1-α-mediated gene expression induced by vitamin B1 deficiency.
Topics: Cell Hypoxia; Cell Nucleus; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Neuroblastoma; Neurons; Pyruvic Acid; Thiamine Deficiency | 2013 |
Metabolic spectroscopy of inflammation in a bleomycin-induced lung injury model using hyperpolarized 1-(13) C pyruvate.
Topics: Analysis of Variance; Animals; Bleomycin; Carbon Isotopes; Disease Models, Animal; Inflammation; Lactic Acid; Lung Injury; Magnetic Resonance Spectroscopy; Male; Pyruvic Acid; Rats, Sprague-Dawley; Time Factors | 2014 |
Metabolic engineering of lactate dehydrogenase rescues mice from acidosis.
Topics: Acidosis; Animals; Boronic Acids; Cells, Cultured; Female; Hypoglycemic Agents; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Metabolic Engineering; Metabolic Networks and Pathways; Metformin; Mice; Mice, Inbred C57BL; Pyruvic Acid | 2014 |
Feasibility of multianimal hyperpolarized (13) C MRS.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Colonic Neoplasms; Cost-Benefit Analysis; Energy Metabolism; Equipment Design; Feasibility Studies; Heterografts; Lactic Acid; Mice; Mice, Nude; Neoplasm Transplantation; Phantoms, Imaging; Pyruvic Acid | 2015 |
Paper microfluidic-based enzyme catalyzed double microreactor.
Topics: Animals; Bioreactors; Cattle; Dihydrolipoamide Dehydrogenase; Enzymes, Immobilized; Equipment Design; Fluorescence; Fluorescent Dyes; L-Lactate Dehydrogenase; Lactic Acid; Microfluidic Analytical Techniques; NAD; Oxazines; Paper; Potassium Chloride; Pyruvic Acid; Serum Albumin, Bovine; Xanthenes | 2014 |
Brain metabolic crisis in traumatic brain injury: what does it mean?
Topics: Brain; Brain Chemistry; Brain Injuries; Humans; Lactic Acid; Microdialysis; Pyruvic Acid | 2014 |
Integrative metabolome and transcriptome profiling reveals discordant glycolysis process between osteosarcoma and normal osteoblastic cells.
Topics: Biomarkers, Tumor; Case-Control Studies; Cyclic GMP-Dependent Protein Kinase Type I; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gluconeogenesis; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Metabolome; Osteoblasts; Osteosarcoma; Phosphopyruvate Hydratase; Predictive Value of Tests; Pyruvic Acid; Sensitivity and Specificity | 2014 |
Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cells.
Topics: Apoptosis; Biological Transport; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Energy Metabolism; Female; Glucose; Glucose Transporter Type 4; Glycolysis; Humans; Lactic Acid; MCF-7 Cells; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyruvic Acid; RNA Interference; RNA, Small Interfering; TOR Serine-Threonine Kinases | 2015 |
FmRα analysis: Rapid and direct estimation of relaxation and kinetic parameters from dynamic nuclear polarization time courses.
Topics: Animals; Ascorbic Acid; Carbon Isotopes; Fumarates; Glutathione; Humans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; Mice; Models, Chemical; Models, Statistical; Pyruvic Acid | 2015 |
The effects of choline on hepatic lipid metabolism, mitochondrial function and antioxidative status in human hepatic C3A cells exposed to excessive energy substrates.
Topics: Antioxidants; Caprylates; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Cell Survival; Choline; DNA Methylation; Down-Regulation; Fatty Acid Synthases; Glutathione Peroxidase; Hepatocytes; Humans; Lactic Acid; Lipid Metabolism; Liver; Membrane Potential, Mitochondrial; Mitochondria; PPAR alpha; Promoter Regions, Genetic; Pyruvic Acid; Reactive Oxygen Species; RNA, Messenger; Triglycerides; Up-Regulation | 2014 |
The impact of anti-apoptotic gene Bcl-2∆ expression on CHO central metabolism.
Topics: Animals; Apoptosis Regulatory Proteins; CHO Cells; Cricetinae; Cricetulus; Lactic Acid; Metabolic Flux Analysis; Mitochondrial Proteins; Proto-Oncogene Proteins c-bcl-2; Pyruvic Acid; Signal Transduction | 2014 |
Lactate and the lactate-to-pyruvate molar ratio cannot be used as independent biomarkers for monitoring brain energetic metabolism: a microdialysis study in patients with traumatic brain injuries.
Topics: Adult; Biomarkers; Brain Injuries; Energy Metabolism; Female; Glucose; Humans; Lactic Acid; Male; Middle Aged; Pyruvic Acid; Young Adult | 2014 |
Using [1-(13) C]lactic acid for hyperpolarized (13) C MR cardiac studies.
Topics: Animals; Bicarbonates; Carbon Isotopes; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2015 |
Protection against intestinal injury from hemorrhagic shock by direct peritoneal resuscitation with pyruvate in rats.
Topics: Animals; Dialysis Solutions; Drug Evaluation, Preclinical; Fluid Therapy; Inflammation Mediators; Intestinal Mucosa; Intestine, Small; Lactic Acid; Male; Microscopy, Electron; Pyruvic Acid; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha | 2014 |
Effects of pyruvate-enriched peritoneal dialysis solution on intestinal barrier in peritoneal resuscitation from hemorrhagic shock in rats.
Topics: Animals; Blood Pressure; Cell Adhesion Molecules; Dialysis Solutions; Disease Models, Animal; Intestinal Mucosa; Lactic Acid; Male; Microfilament Proteins; Peritoneal Dialysis; Phosphoproteins; Phosphorylation; Pyruvic Acid; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Zonula Occludens-1 Protein | 2015 |
The effect of metformin treatment in vivo on acute and long-term energy metabolism and progesterone production in vitro by granulosa cells from women with polycystic ovary syndrome.
Topics: Adult; Case-Control Studies; Cell Proliferation; Cells, Cultured; Female; Follicular Fluid; Glucose; Granulosa Cells; Humans; Insulin; Lactic Acid; Metformin; Ovarian Follicle; Polycystic Ovary Syndrome; Progesterone; Pyruvic Acid | 2014 |
Bedside evaluation of cerebral energy metabolism in severe community-acquired bacterial meningitis.
Topics: Adolescent; Adult; Aged; Brain Ischemia; Child; Child, Preschool; Disease Transmission, Infectious; Energy Metabolism; Humans; Infant; Lactic Acid; Meningitis, Bacterial; Microdialysis; Middle Aged; Mitochondrial Diseases; Pyruvic Acid; Young Adult | 2015 |
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.
Topics: Acetylation; Blotting, Western; Cell Proliferation; Fluorescent Antibody Technique; Glucose; Glycolysis; Humans; Immunoprecipitation; Lactic Acid; Lysine; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Phenotype; Protein Processing, Post-Translational; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Reactive Oxygen Species; Sirtuin 3; Tumor Cells, Cultured | 2014 |
Hyperpolarized 13C NMR detects rapid drug-induced changes in cardiac metabolism.
Topics: Adrenergic beta-Agonists; Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Glycogen; Heart; Isoproterenol; Isotope Labeling; Lactic Acid; Male; Metabolic Clearance Rate; Myocardium; Pyruvic Acid; Radiopharmaceuticals; Rats; Reproducibility of Results; Sensitivity and Specificity | 2015 |
Effect of rhubarb pre-treatment on intestinal microcirculation in septic rats.
Topics: Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dobutamine; Endothelial Cells; Humans; Intestinal Mucosa; Lactic Acid; Male; Microcirculation; Oxygen; Plant Extracts; Platelet Endothelial Cell Adhesion Molecule-1; Pyruvic Acid; Rats, Sprague-Dawley; Rheum; Sepsis; Umbilical Veins | 2014 |
Effects of experimental tooth clenching on pain and intramuscular release of 5-HT and glutamate in patients with myofascial TMD.
Topics: Adult; Bite Force; Case-Control Studies; Estradiol; Facial Pain; Female; Glutamic Acid; Humans; Hydrocortisone; Lactic Acid; Male; Masseter Muscle; Motor Activity; Muscle Fatigue; Pain Measurement; Pain Perception; Pyruvic Acid; Regional Blood Flow; Saliva; Serotonin; Temporomandibular Joint Disorders | 2015 |
A microbial biosensor based on Lactobacillus delbruecki sp. bacterial cells for simultaneous determination of lactic and pyruvic acid.
Topics: Biosensing Techniques; Cells, Immobilized; Lactic Acid; Lactobacillus delbrueckii; Pyruvic Acid; Temperature | 2015 |
Parental environmental exposure leads to glycometabolic disturbances that affect fertilization of eggs in the silkworm Bombyx mori: the parental transcript legacy.
Topics: Animals; Bombyx; Citric Acid Cycle; Environmental Exposure; Fertilization; Germ Cells; Glycolysis; Lactic Acid; Light; NAD; Pyruvic Acid; Real-Time Polymerase Chain Reaction | 2015 |
Lactate dehydrogenase is the key enzyme for pneumococcal pyruvate metabolism and pneumococcal survival in blood.
Topics: Animals; Bacteremia; Blood; Disease Models, Animal; Female; Fermentation; Gene Deletion; L-Lactate Dehydrogenase; Lactic Acid; Mice; Microbial Viability; Pneumonia, Pneumococcal; Pyruvic Acid; Streptococcus pneumoniae; Virulence | 2014 |
The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Bacterial Proteins; Catalysis; Catalytic Domain; Fructosediphosphates; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; Motion; Mutation; Protein Structure, Quaternary; Protein Structure, Tertiary; Pyruvic Acid; Sequence Homology, Amino Acid; Static Electricity; Thermus | 2014 |
Hollow microgel based ultrathin thermoresponsive membranes for separation, synthesis, and catalytic applications.
Topics: Catalysis; Coloring Agents; Cross-Linking Reagents; Enzymes, Immobilized; Gels; Gold; L-Lactate Dehydrogenase; Lactic Acid; Membranes, Artificial; Metal Nanoparticles; Microscopy, Electron, Scanning; Muramidase; NAD; Pyruvic Acid; Temperature; Water | 2014 |
Effect of swimming on the production of aldosterone in rats.
Topics: Aldosterone; Angiotensin II; Animals; Catheterization, Central Venous; Immersion; Lactic Acid; Male; Phosphoproteins; Primary Cell Culture; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Swimming; Water; Zona Glomerulosa | 2014 |
Chemical shift separation with controlled aliasing for hyperpolarized (13) C metabolic imaging.
Topics: Animals; Carbon Isotopes; Computer Simulation; Image Processing, Computer-Assisted; Kidney; Lactic Acid; Magnetic Resonance Imaging; Phantoms, Imaging; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2015 |
Real-time assessment of ¹³C metabolism reveals an early lactate increase in the brain of rats with acute liver failure.
Topics: Alanine; Animals; Brain; Carbon; Carbon Isotopes; Computer Systems; Disease Progression; Lactic Acid; Liver Failure, Acute; Male; Pyruvic Acid; Rats, Sprague-Dawley | 2015 |
Perioperative microdialysis in meningioma surgery: correlation of cerebral metabolites with clinical outcome.
Topics: Adult; Aged; Brain; Female; Glasgow Coma Scale; Glucose; Glycerol; Humans; Lactic Acid; Male; Meningeal Neoplasms; Meningioma; Microdialysis; Middle Aged; Postoperative Period; Pyruvic Acid; Treatment Outcome | 2014 |
Metabolic regulation of collagen gel contraction by porcine aortic valvular interstitial cells.
Topics: Animals; Aortic Valve; Cell Survival; Collagen; Extracellular Matrix; Galactose; Glucose; Glutamic Acid; Heart Valve Diseases; Lactic Acid; Pyruvic Acid; Swine | 2014 |
Cholinergic neurons of the basal forebrain mediate biochemical and electrophysiological mechanisms underlying sleep homeostasis.
Topics: Adenosine; Animals; Antibodies, Monoclonal; Basal Forebrain; Cholinergic Neurons; Delta Rhythm; Homeostasis; Lactic Acid; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroso Compounds; Pyruvic Acid; Rats, Wistar; Ribosome Inactivating Proteins, Type 1; Saporins; Sleep; Sleep Deprivation; Theta Rhythm | 2015 |
Suppression of microbial metabolic pathways inhibits the generation of the human body odor component diacetyl by Staphylococcus spp.
Topics: Carbon Isotopes; Chromatography, High Pressure Liquid; Citric Acid; Cosmetics; Diacetyl; Fatty Acids; Glycolysis; Humans; Lactic Acid; Male; Microscopy, Electron, Scanning; Odorants; Pyruvic Acid; Skin; Staphylococcus aureus; Staphylococcus epidermidis; Sweat | 2014 |
Interstitial lactate, lactate/pyruvate and glucose in rat muscle before, during and in the recovery from global hypoxia.
Topics: Animals; Energy Metabolism; Glucose; Hypoxia; Lactic Acid; Male; Microdialysis; Muscle, Skeletal; Pyruvic Acid; Rats; Rats, Wistar | 2014 |
Analysis of carbon substrates used by Listeria monocytogenes during growth in J774A.1 macrophages suggests a bipartite intracellular metabolism.
Topics: Animals; Bacterial Proteins; Carbon; Catalysis; Cell Line; Gluconeogenesis; Glucose-6-Phosphate; Glycerol; Host-Pathogen Interactions; Lactic Acid; Listeria monocytogenes; Macrophages; Mice; Mutation; Pyruvic Acid | 2014 |
Intramuscular pain modulatory substances before and after exercise in women with chronic neck pain.
Topics: Adult; beta-Endorphin; Chronic Disease; Exercise Therapy; Female; Glutamic Acid; Humans; Hydrocortisone; Lactic Acid; Microdialysis; Middle Aged; Neck Pain; Pain Measurement; Pain Threshold; Pyruvic Acid; Shoulder Pain; Substance P; Superficial Back Muscles; Young Adult | 2015 |
In vivo continuous and simultaneous monitoring of brain energy substrates with a multiplex amperometric enzyme-based biosensor device.
Topics: Animals; Biosensing Techniques; Glucose; Lactic Acid; Male; Monitoring, Physiologic; Pyruvic Acid; Rats | 2015 |
Tissue ischemia microdialysis assessments following severe traumatic haemorrhagic shock: lactate/pyruvate ratio as a new resuscitation end point?
Topics: Adult; Cardiac Output; Female; Hemoglobins; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Prospective Studies; Pyruvic Acid; Resuscitation; Severity of Illness Index; Shock, Hemorrhagic; Shock, Traumatic; Young Adult | 2014 |
Aromatic catabolic pathway selection for optimal production of pyruvate and lactate from lignin.
Topics: Lactic Acid; Lignin; Metabolic Engineering; Pseudomonas putida; Pyruvic Acid | 2015 |
BcMctA, a putative monocarboxylate transporter, is required for pathogenicity in Botrytis cinerea.
Topics: Acetic Acid; Amino Acid Sequence; Botrytis; Cucumis sativus; Fungal Proteins; Gene Expression Regulation, Fungal; Lactic Acid; Molecular Sequence Data; Monocarboxylic Acid Transporters; Mutagenesis, Insertional; Plant Diseases; Plant Leaves; Pyruvic Acid; Solanum lycopersicum; Spores, Fungal; Virulence | 2015 |
Determination of pyruvate and lactate as potential biomarkers of embryo viability in assisted reproduction by capillary electrophoresis with contactless conductivity detection.
Topics: Biomarkers; Culture Media; Electric Conductivity; Electrophoresis, Capillary; Embryo, Mammalian; Humans; Lactic Acid; Limit of Detection; Pyruvic Acid; Reproductive Techniques, Assisted; Temperature | 2015 |
Biochemical neuromonitoring of poor-grade aneurysmal subarachnoid hemorrhage: comparative analysis of metabolic events detected by cerebral microdialysis and by retrograde jugular vein catheterization.
Topics: Adolescent; Adult; Biomarkers; Brain; Catheterization; Female; Glasgow Outcome Scale; Humans; Intracranial Aneurysm; Jugular Veins; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Prognosis; Prospective Studies; Pyruvic Acid; Sensitivity and Specificity; Subarachnoid Hemorrhage | 2015 |
13C-MR Spectroscopic Imaging with Hyperpolarized [1-13C]pyruvate Detects Early Response to Radiotherapy in SCC Tumors and HT-29 Tumors.
Topics: Animals; Carbon Isotopes; Carcinoma, Squamous Cell; Colonic Neoplasms; HT29 Cells; Humans; Lactic Acid; Magnetic Resonance Imaging; Mice; Pyruvic Acid; Radiography; Xenograft Model Antitumor Assays | 2015 |
Increased serum fibroblast growth factor 21 levels in patients with schizophrenia.
Topics: Adult; Case-Control Studies; Citric Acid Cycle; Female; Fibroblast Growth Factors; Humans; Ketoglutaric Acids; Lactic Acid; Malates; Male; Middle Aged; Pyruvic Acid; Schizophrenia; Young Adult | 2015 |
Development of an enzymatic assay to measure lactate in perchloric acid-precipitated whole blood.
Topics: Enzyme Assays; Humans; Lactic Acid; Mixed Function Oxygenases; Perchlorates; Pyruvic Acid | 2015 |
Metabolomics specificity of tuberculosis plasma revealed by (1)H NMR spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Community-Acquired Infections; Diabetes Mellitus, Type 2; Discriminant Analysis; Female; Humans; Ketone Bodies; Lactic Acid; Least-Squares Analysis; Male; Metabolomics; Middle Aged; Neoplasms; Pneumonia; Predictive Value of Tests; Prognosis; Prospective Studies; Proton Magnetic Resonance Spectroscopy; Pyruvic Acid; Tuberculosis | 2015 |
Channel-mediated lactate release by K⁺-stimulated astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Barium; Cadmium; Cells, Cultured; Cerebral Cortex; Female; Fluoresceins; Glycogen; Humans; In Vitro Techniques; Ion Channels; Ions; Lactic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Potassium; Pyruvic Acid; Somatosensory Cortex; Transfection | 2015 |
Hydroxyethyl starch (HES 130/0.4) impairs intestinal barrier integrity and metabolic function: findings from a mouse model of the isolated perfused small intestine.
Topics: Animals; Endothelium, Vascular; Female; Hydroxyethyl Starch Derivatives; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Lactic Acid; Mice; Mice, Inbred C57BL; Perfusion; Permeability; Pyruvic Acid | 2015 |
Simultaneous imaging of 13C metabolism and 1H structure: technical considerations and potential applications.
Topics: Animals; Carbon Isotopes; Image Interpretation, Computer-Assisted; Kidney; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Inbred ICR; Molecular Imaging; Phantoms, Imaging; Protons; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity | 2015 |
Brain glucose metabolism in an animal model of depression.
Topics: Administration, Oral; Animals; Brain; Depression; Disease Models, Animal; Female; Glucose; Glucosephosphate Dehydrogenase; Hexokinase; Lactic Acid; Male; Mitochondria; Phosphofructokinases; Pregnancy; Prenatal Exposure Delayed Effects; Pyruvate Kinase; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Swimming | 2015 |
Measurement of the acute metabolic response to hypoxia in rat tumours in vivo using magnetic resonance spectroscopy and hyperpolarised pyruvate.
Topics: Animals; Carbon Isotopes; Disease Models, Animal; Fibrosarcoma; Hypoxia; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats | 2015 |
Stability of lactate and pyruvate in cerebrospinal fluid under typical clinical laboratory storage conditions.
Topics: Clinical Laboratory Techniques; Humans; Lactic Acid; Pyruvic Acid; Specimen Handling | 2015 |
Analysis of olfactory sensitivity in rainbow trout (Oncorhynchus mykiss) reveals their ability to detect lactic acid, pyruvic acid and four B vitamins.
Topics: Animals; Electrodiagnosis; Female; Humans; Lactic Acid; Male; Odorants; Oncorhynchus mykiss; Pyruvic Acid; Skin; Smell; Vitamin B Complex | 2015 |
Is microdialysis useful for early detection of acute rejection after kidney transplantation?
Topics: Acute Disease; Animals; Biomarkers; Disease Models, Animal; Early Diagnosis; Glucose; Glycerol; Graft Rejection; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Lactic Acid; Microdialysis; Monitoring, Physiologic; Pyruvic Acid; Sus scrofa | 2015 |
Metabolic responses during hemodialysis determined by quantitative (1)H NMR spectroscopy.
Topics: Aged; Alanine; Creatinine; Female; Humans; Kidney Failure, Chronic; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pyruvic Acid; Renal Dialysis; Valine | 2015 |
Mitochondrial networks in cardiac myocytes reveal dynamic coupling behavior.
Topics: Animals; Cells, Cultured; Glucose; Guinea Pigs; Heart Ventricles; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria, Heart; Models, Cardiovascular; Myocytes, Cardiac; Pyruvic Acid; Reactive Oxygen Species | 2015 |
The progression from a lower to a higher invasive stage of bladder cancer is associated with severe alterations in glucose and pyruvate metabolism.
Topics: Alanine; Alanine Transaminase; Cell Line, Tumor; Disease Progression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasm Invasiveness; Neoplasm Staging; Phosphofructokinase-1; Pyruvic Acid; Urinary Bladder Neoplasms | 2015 |
Application of flow sensitive gradients for improved measures of metabolism using hyperpolarized (13) c MRI.
Topics: Animals; Carbon Isotopes; Computer Simulation; Lactic Acid; Magnetic Resonance Imaging; Metabolome; Metabolomics; Mice; Mice, Inbred ICR; Pyruvic Acid; Signal Processing, Computer-Assisted | 2016 |
In boar sperm capacitation L-lactate and succinate, but not pyruvate and citrate, contribute to the mitochondrial membrane potential increase as monitored via safranine O fluorescence.
Topics: Animals; Citric Acid; Fluorescent Dyes; Lactic Acid; Male; Membrane Potential, Mitochondrial; Models, Biological; Phenazines; Pyruvic Acid; Sperm Capacitation; Succinic Acid; Sus scrofa | 2015 |
In vitro leishmanicidal activity of 1,3-disubstituted 5-nitroindazoles.
Topics: Acetates; Alanine; Animals; Antiprotozoal Agents; Glycine; In Vitro Techniques; Indazoles; Lactic Acid; Leishmania braziliensis; Leishmania infantum; Leishmaniasis, Visceral; Macrophages; Magnetic Resonance Spectroscopy; Mice; Microscopy, Electron, Transmission; Mitochondria; Organelles; Pyruvic Acid; Succinic Acid | 2015 |
Low-level light in combination with metabolic modulators for effective therapy of injured brain.
Topics: Animals; Brain Injuries; Cell Hypoxia; Cell Line, Tumor; Hippocampus; Humans; Lactic Acid; Light; Membrane Potential, Mitochondrial; Mice; Pyruvic Acid | 2015 |
[Effect of Hypecoum erectum extract on morphofunctional state of the liver in rats with tetracycline-associated hepatitis].
Topics: Adenosine Triphosphate; Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; Glutathione; Lactic Acid; Lipid Peroxidation; Liver; Male; Malondialdehyde; Papaveraceae; Plant Extracts; Protective Agents; Pyruvic Acid; Rats; Rats, Wistar; Tetracycline | 2014 |
Hyperbaric oxygen therapy ameliorates acute brain injury after porcine intracerebral hemorrhage at high altitude.
Topics: Altitude; Animals; Brain; Brain Edema; Cerebral Hemorrhage; Glutamic Acid; Hyperbaric Oxygenation; Lactic Acid; Models, Animal; Neurons; Oxygen; Pyruvic Acid; Swine | 2015 |
Dynamic UltraFast 2D EXchange SpectroscopY (UF-EXSY) of hyperpolarized substrates.
Topics: Alanine; Carcinoma, Renal Cell; Cell Line, Tumor; Enzyme Inhibitors; Enzymes; Humans; Kidney Neoplasms; L-Lactate Dehydrogenase; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Nuclear Magnetic Resonance, Biomolecular; Pyruvic Acid; Reproducibility of Results; Urea | 2015 |
Direct dynamic measurement of intracellular and extracellular lactate in small-volume cell suspensions with (13)C hyperpolarised NMR.
Topics: Biological Transport; Carbon-13 Magnetic Resonance Spectroscopy; Cell Count; Cell Line, Tumor; Extracellular Fluid; Humans; Intracellular Fluid; Lactic Acid; Male; Prostatic Neoplasms; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity | 2015 |
Yeast cell-based analysis of human lactate dehydrogenase isoforms.
Topics: Biocatalysis; Enzyme Assays; Fermentation; Genetic Complementation Test; High-Throughput Screening Assays; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Luminescent Proteins; Pyruvic Acid; Red Fluorescent Protein; Saccharomyces cerevisiae | 2015 |
[Clinical characteristics and genetic analysis of two cases with Leigh syndrome with acute pulmonary hemorrhage as predominant manifestation].
Topics: Brain; Carnitine; DNA, Mitochondrial; Female; Genetic Testing; Hemorrhage; Humans; Infant; Lactic Acid; Leigh Disease; Lung Diseases; Magnetic Resonance Imaging; Male; Mutation; Pyruvic Acid | 2015 |
Hyperpolarized [1-(13) C]pyruvate MRI for noninvasive examination of placental metabolism and nutrient transport: A feasibility study in pregnant guinea pigs.
Topics: Animals; Feasibility Studies; Female; Fetus; Guinea Pigs; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Imaging; Placenta; Pregnancy; Pyruvic Acid; Signal Processing, Computer-Assisted | 2016 |
[Metabolomics Study on Non-Small Cell Lung Cancer Patients with Different Chinese Medical Syndromes].
Topics: Asian People; Carcinoma, Non-Small-Cell Lung; Gas Chromatography-Mass Spectrometry; Humans; Lactic Acid; Least-Squares Analysis; Metabolomics; Principal Component Analysis; Pyruvic Acid | 2015 |
NH4(+) triggers the release of astrocytic lactate via mitochondrial pyruvate shunting.
Topics: Ammonium Compounds; Animals; Astrocytes; Lactic Acid; Mice; Mitochondria; Pyruvic Acid | 2015 |
Retrograde Cerebral Perfusion Results in Better Perfusion to the Striatum Than the Cerebral Cortex During Deep Hypothermic Circulatory Arrest: A Microdialysis Study.
Topics: Animals; Cerebral Cortex; Cerebrovascular Circulation; Circulatory Arrest, Deep Hypothermia Induced; Corpus Striatum; Glucose; Glutamic Acid; Glycerol; Hemodynamics; Lactic Acid; Microdialysis; Perfusion; Pyruvic Acid; Swine | 2016 |
Simultaneous Hyperpolarized 13C-Pyruvate MRI and 18F-FDG PET (HyperPET) in 10 Dogs with Cancer.
Topics: Animals; Dog Diseases; Dogs; Fluorodeoxyglucose F18; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Multimodal Imaging; Neoplasms; Positron-Emission Tomography; Prognosis; Pyruvic Acid; Radiopharmaceuticals | 2015 |
Hyperpolarized magnetic resonance spectroscopy for assessing tumor hypoxia.
Topics: Administration, Inhalation; Animals; Cell Hypoxia; Female; Lactic Acid; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Mice, Inbred C3H; Oxygen; Pyruvic Acid | 2015 |
Hyperpolarized 13C NMR observation of lactate kinetics in skeletal muscle.
Topics: Animals; Bicarbonates; Carbon-13 Magnetic Resonance Spectroscopy; Dichloroacetic Acid; Glutamic Acid; Lactic Acid; Male; Muscle, Skeletal; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2015 |
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells.
Topics: Acetates; Acetyl Coenzyme A; Animals; Carbon Radioisotopes; Cells, Cultured; Citric Acid Cycle; Cytosol; Glucose; Lactic Acid; Malates; Mitochondria; Neural Stem Cells; Oligodendroglia; Oxaloacetic Acid; Pentose Phosphate Pathway; Phosphoenolpyruvate; Pyruvic Acid; Radiopharmaceuticals; Rats, Sprague-Dawley | 2016 |
Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders.
Topics: Adolescent; Adult; Biomarkers; Child; Creatine Kinase; Female; Fibroblast Growth Factors; Growth Differentiation Factor 15; Humans; Lactic Acid; Male; MELAS Syndrome; Middle Aged; Mitochondrial Diseases; Pyruvic Acid; ROC Curve; Young Adult | 2015 |
Major contribution of the type II beta carbonic anhydrase CanB (Cj0237) to the capnophilic growth phenotype of Campylobacter jejuni.
Topics: Aspartic Acid; Bicarbonates; Campylobacter jejuni; Carbon Dioxide; Carbonic Anhydrase II; Culture Media; Lactic Acid; Oxaloacetic Acid; Oxygen; Phenotype; Pyruvate Carboxylase; Pyruvic Acid; Serine | 2016 |
Reduction of D-lactate content in sauerkraut using starter cultures of recombinant Leuconostoc mesenteroides expressing the ldhL gene.
Topics: Brassica; Fermentation; Food Microbiology; L-Lactate Dehydrogenase; Lactic Acid; Lactobacillus plantarum; Leuconostoc; Metabolic Flux Analysis; Pyruvic Acid | 2016 |
Selective spectroscopic imaging of hyperpolarized pyruvate and its metabolites using a single-echo variable phase advance method in balanced SSFP.
Topics: A549 Cells; Alanine; Algorithms; Animals; Biomarkers, Tumor; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Nude; Molecular Imaging; Neoplasms, Experimental; Pyruvic Acid; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted | 2016 |
Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Deoxyglucose; Disease Models, Animal; Disease Susceptibility; DNA Damage; Electron Transport Complex IV; Female; Glycolysis; Humans; Lactic Acid; Lung; Lung Neoplasms; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Monocarboxylic Acid Transporters; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Pyruvic Acid; Reactive Oxygen Species; Stress, Physiological; Symporters; Urethane | 2016 |
Pyruvate to Lactate Metabolic Changes during Neurodevelopment Measured Dynamically Using Hyperpolarized 13C Imaging in Juvenile Murine Brain.
Topics: Adolescent; Aging; Animals; Brain; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Neuroimaging; Neurons; Pyruvic Acid | 2016 |
Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.
Topics: Animals; Autoimmunity; CD4-Positive T-Lymphocytes; Cells, Cultured; Deoxyglucose; Dichloroacetic Acid; Disease Models, Animal; Energy Metabolism; Glucose; Interferon-gamma; Interleukin-17; Lactic Acid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Metformin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Pyruvic Acid | 2016 |
Alpha-Oxo Acids Assisted Transformation of FeS to Fe3S4 at Low Temperature: Implications for Abiotic, Biotic, and Prebiotic Mineralization.
Topics: Acetaldehyde; Crystallization; Formaldehyde; Glyoxylates; Iron; Keto Acids; Ketoglutaric Acids; Lactic Acid; Magnetics; Magnetosomes; Oxaloacetic Acid; Oxidation-Reduction; Pentanoic Acids; Phase Transition; Phenylpyruvic Acids; Pyruvic Acid; Sulfides; Temperature; X-Ray Diffraction | 2015 |
Expression of Lactate Dehydrogenase in Aspergillus niger for L-Lactic Acid Production.
Topics: Animals; Aspergillus niger; Bioreactors; Biosynthetic Pathways; Fermentation; Fungal Proteins; Gene Expression; L-Lactate Dehydrogenase; Lactic Acid; Mice; Pyruvic Acid | 2015 |
Penicillamine prevents ram sperm agglutination in media that support capacitation.
Topics: Albumins; Animals; Culture Media; Isotonic Solutions; Lactic Acid; Male; Organ Preservation Solutions; Penicillamine; Pyruvic Acid; Semen Analysis; Semen Preservation; Sheep; Sperm Agglutination; Sperm Capacitation | 2016 |
Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.
Topics: Alcohol Oxidoreductases; Carbohydrate Metabolism; Gene Expression; Glutarates; Ketoglutarate Dehydrogenase Complex; Kinetics; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; Oxaloacetic Acid; Phosphoglycerate Dehydrogenase; Pyruvic Acid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity | 2016 |
Accelerated 3D echo-planar imaging with compressed sensing for time-resolved hyperpolarized
Topics: Algorithms; Animals; Artifacts; Carbon-13 Magnetic Resonance Spectroscopy; Data Compression; Echo-Planar Imaging; Image Enhancement; Imaging, Three-Dimensional; Kidney; Lactic Acid; Molecular Imaging; Motion; Phantoms, Imaging; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted | 2017 |
Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth.
Topics: Animals; Diet; Dietary Sucrose; Disease Models, Animal; Drosophila; Female; Lactic Acid; Male; Mitochondria; Pyruvic Acid; Reactive Oxygen Species | 2016 |
Metabolic crisis occurs with seizures and periodic discharges after brain trauma.
Topics: Adult; Aged; Aged, 80 and over; Brain Injuries; Electroencephalography; Female; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Pyruvic Acid; Seizures; Severity of Illness Index; Young Adult | 2016 |
The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Membrane; Indazoles; Ion Transport; Lactic Acid; Male; Membrane Transport Proteins; Mitochondrial Proteins; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Wistar; Solute Carrier Proteins; Symporters | 2016 |
Metabolism of hyperpolarized [1-(13)C]pyruvate through alternate pathways in rat liver.
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Citric Acid Cycle; Gluconeogenesis; Lactic Acid; Liver; Magnetic Resonance Spectroscopy; Phosphoenolpyruvate Carboxykinase (ATP); Proton Magnetic Resonance Spectroscopy; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats, Sprague-Dawley | 2016 |
A novel perfused Bloch-McConnell simulator for analyzing the accuracy of dynamic hyperpolarized MRS.
Topics: Animals; Cell Transformation, Neoplastic; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Models, Biological; Perfusion; Pyruvic Acid; Signal-To-Noise Ratio; Thyroid Neoplasms | 2016 |
Staphylococcus aureus lactate- and malate-quinone oxidoreductases contribute to nitric oxide resistance and virulence.
Topics: Adenosine Triphosphate; Amino Acids; Catalysis; Lactic Acid; Nitric Oxide; Oxidoreductases; Peptides; Pyruvic Acid; Staphylococcus aureus; Substrate Specificity; Virulence | 2016 |
Extracellular production of tellurium nanoparticles by the photosynthetic bacterium Rhodobacter capsulatus.
Topics: Fructose; Lactic Acid; Malates; Nanoparticles; Naphthoquinones; Photosynthesis; Pyruvic Acid; Rhodobacter capsulatus; Tellurium | 2016 |
A multisample dissolution dynamic nuclear polarization system for serial injections in small animals.
Topics: Animals; Bicarbonates; Equipment Design; Female; Heart; Injections; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2017 |
Single shot three-dimensional pulse sequence for hyperpolarized
Topics: Animals; Carbon Isotopes; Female; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phantoms, Imaging; Pyruvic Acid | 2017 |
Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR.
Topics: Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Protons; Pyruvic Acid; Solubility; Time Factors | 2016 |
Neuron-Specific Enolase Is Correlated to Compromised Cerebral Metabolism in Patients Suffering from Acute Bacterial Meningitis; An Observational Cohort Study.
Topics: Acute Disease; Adolescent; Adult; Aged; Biomarkers; Brain; Cohort Studies; Female; Glucose; Humans; Intracranial Pressure; Lactic Acid; Male; Meningitis, Bacterial; Microdialysis; Middle Aged; Monitoring, Physiologic; Phosphopyruvate Hydratase; Pyruvic Acid; S100 Calcium Binding Protein beta Subunit; Young Adult | 2016 |
Detection of localized changes in the metabolism of hyperpolarized gluconeogenic precursors
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Gluconeogenesis; Glucose; Kidney; Lactic Acid; Liver; Male; Metabolic Clearance Rate; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 2017 |
Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation.
Topics: Adenosine Triphosphate; Biosynthetic Pathways; Cell Line, Tumor; Enzyme Induction; Epithelial-Mesenchymal Transition; Glucose; Glycogen; Glycosylation; Hexosamines; Humans; Lactic Acid; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Pyruvic Acid; Transforming Growth Factor beta | 2016 |
Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs.
Topics: Animals; Bicarbonates; Burns; Capillary Permeability; Disease Models, Animal; Dogs; Fluid Therapy; Fluorescein-5-isothiocyanate; Glucose; Hemodynamics; Lactic Acid; Platelet Activating Factor; Potassium Chloride; Pyruvic Acid; Random Allocation; Shock; Sodium Chloride; Vascular Endothelial Growth Factor A | 2016 |
Trifluorosubstrates as mechanistic probes for an FMN-dependent l-2-hydroxy acid-oxidizing enzyme.
Topics: Binding Sites; Biocatalysis; Catalytic Domain; Flavin Mononucleotide; Halogenation; Humans; Hydrogen Bonding; Hydroxybutyrates; Kinetics; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; Protein Binding; Protein Domains; Protons; Pyruvic Acid; Recombinant Proteins; Substrate Specificity | 2016 |
Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents.
Topics: Carbon Isotopes; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Phantoms, Imaging; Pyruvic Acid; Reproducibility of Results | 2016 |
Microdialysis Assessment of Cerebral Perfusion during Cardiac Arrest, Extracorporeal Life Support and Cardiopulmonary Resuscitation in Rats - A Pilot Trial.
Topics: Animals; Biomarkers; Blood Pressure; CA1 Region, Hippocampal; Cardiopulmonary Resuscitation; Cerebral Cortex; Disease Models, Animal; Extracorporeal Membrane Oxygenation; Glucose; Glutamic Acid; Heart Arrest; Hemodynamics; Lactic Acid; Male; Microdialysis; Oxygen; Perfusion; Pyruvic Acid; Rats | 2016 |
Skeletal muscle lactate overproduction during metformin intoxication: An animal study with reverse microdialysis.
Topics: Acidosis, Lactic; Animals; Glycolysis; Hypoglycemic Agents; Infusions, Parenteral; Lactic Acid; Metformin; Microdialysis; Mitochondria, Muscle; Muscle, Skeletal; Pyruvic Acid; Swine; Time Factors | 2016 |
Biochemical indications of cerebral ischaemia and mitochondrial dysfunction in severe brain trauma analysed with regard to type of lesion.
Topics: Adult; Brain Injuries, Traumatic; Brain Ischemia; Cerebral Infarction; Energy Metabolism; Female; Glucose; Humans; Lactic Acid; Male; Middle Aged; Mitochondria; Pyruvic Acid | 2016 |
Optimizing Flip Angles for Metabolic Rate Estimation in Hyperpolarized Carbon-13 MRI.
Topics: Algorithms; Animals; Carbon Isotopes; Computer Simulation; Disease Models, Animal; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Male; Mice; Prostatic Neoplasms; Pyruvic Acid | 2016 |
Assessing the transport rate of hyperpolarized pyruvate and lactate from the intra- to the extracellular space.
Topics: Biological Transport, Active; Carbon-13 Magnetic Resonance Spectroscopy; Cell Membrane; Contrast Media; Extracellular Space; Humans; Intracellular Space; Lactic Acid; MCF-7 Cells; Metabolic Clearance Rate; Organometallic Compounds; Proton Magnetic Resonance Spectroscopy; Pyruvic Acid; Radiopharmaceuticals | 2016 |
Voxel-by-voxel correlations of perfusion, substrate, and metabolite signals in dynamic hyperpolarized (13) C imaging.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Contrast Media; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Molecular Imaging; Neovascularization, Pathologic; Pyruvic Acid; Rats; Rats, Nude; Signal Processing, Computer-Assisted | 2016 |
Conformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr(215) in Aerococcus viridans lactate oxidase.
Topics: Aerococcus; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Mixed Function Oxygenases; Molecular Dynamics Simulation; Mutation; Phenylalanine; Protein Conformation; Pyruvic Acid; Tyrosine | 2016 |
Lactate and Pyruvate Are Major Sources of Energy for Stallion Sperm with Dose Effects on Mitochondrial Function, Motility, and ROS Production.
Topics: Animals; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Horses; Lactic Acid; Male; Mitochondria; Oxidative Phosphorylation; Pyruvic Acid; Reactive Oxygen Species; Sperm Motility; Spermatozoa | 2016 |
Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model.
Topics: Adenosine Triphosphate; Animals; Atorvastatin; Creatine Kinase; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lactic Acid; Male; Microscopy, Electron, Transmission; Mitochondria, Muscle; Motor Activity; Muscle, Skeletal; Muscular Diseases; Myoglobin; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ubiquinone | 2016 |
Probing lactate secretion in tumours with hyperpolarised NMR.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Lactic Acid; Magnetic Resonance Imaging; Male; Molecular Imaging; Molecular Probe Techniques; Neoplasms, Experimental; Pyruvic Acid; Rats; Rats, Inbred F344; Reproducibility of Results; Sensitivity and Specificity | 2016 |
Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro.
Topics: Aldehyde Reductase; Aldo-Keto Reductases; Ammonia; Caprylates; Cell Line, Tumor; Cholesterol; Fatty Acids, Nonesterified; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Hepatocytes; Histones; Humans; Lactic Acid; Lipid Peroxidation; Lipogenesis; Models, Biological; Molecular Sequence Annotation; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Protein Biosynthesis; Proteomics; Pyruvic Acid | 2016 |
Accelerated chemical shift imaging of hyperpolarized (13) C metabolites.
Topics: Algorithms; Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Kidney; Lactic Acid; Magnetic Resonance Imaging; Molecular Imaging; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution | 2016 |
Impairment of oxidative phosphorylation increases the toxicity of SYD-1 on hepatocarcinoma cells (HepG2).
Topics: Adenosine Triphosphate; Antineoplastic Agents; Carcinoma, Hepatocellular; Hep G2 Cells; Hepatocytes; Humans; Lactic Acid; Liver; Liver Neoplasms; Mitochondria, Liver; Oxadiazoles; Oxidative Phosphorylation; Pyruvic Acid | 2016 |
Separation of extra- and intracellular metabolites using hyperpolarized (13)C diffusion weighted MR.
Topics: Bioreactors; Carbon Isotopes; Cell Line, Tumor; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pyruvic Acid | 2016 |
Evaluation of oxidative stress markers in the heart and liver of rainbow trout (Oncorhynchus mykiss walbaum) exposed to the formalin.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Disinfectants; Fish Proteins; Formaldehyde; L-Lactate Dehydrogenase; Lactic Acid; Liver; Myocardium; Oncorhynchus mykiss; Oxidative Stress; Protein Carbonylation; Pyruvic Acid; Thiobarbituric Acid Reactive Substances | 2016 |
Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring.
Topics: Biomarkers, Tumor; Brain Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Glioma; Humans; Isocitrate Dehydrogenase; Lactic Acid; Pyruvic Acid; Tumor Cells, Cultured | 2016 |
Comprehensive metabolic modeling of multiple 13C-isotopomer data sets to study metabolism in perfused working hearts.
Topics: Acetyl Coenzyme A; Animals; Carbon Isotopes; Energy Metabolism; Glucose; Isolated Heart Preparation; Lactic Acid; Male; Metabolic Flux Analysis; Metabolic Networks and Pathways; Mice; Models, Biological; Models, Cardiovascular; Myocardium; Oleic Acid; Pyruvic Acid | 2016 |
d-Lactate Dehydrogenase Links Methylglyoxal Degradation and Electron Transport through Cytochrome c.
Topics: Arabidopsis; Arabidopsis Proteins; Biocatalysis; Blotting, Western; Cells, Cultured; Cytochromes c; Electron Transport; L-Lactate Dehydrogenase; Lactic Acid; Mass Spectrometry; Microscopy, Confocal; Mitochondrial Membranes; Mutation; Oxidation-Reduction; Oxygen Consumption; Plants, Genetically Modified; Pyruvaldehyde; Pyruvic Acid | 2016 |
Pioglitazone increases the glycolytic efficiency of human Sertoli cells with possible implications for spermatogenesis.
Topics: Dose-Response Relationship, Drug; Glucose; Glycolysis; Humans; Lactic Acid; Male; Membrane Potential, Mitochondrial; Oxidative Stress; Pioglitazone; Pyruvic Acid; Sertoli Cells; Spermatogenesis; Thiazolidinediones | 2016 |
Ex vivo hyperpolarized MR spectroscopy on isolated renal tubular cells: A novel technique for cell energy phenotyping.
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Cells, Cultured; Cytological Techniques; Kidney Cortex; Kidney Tubules; Lactic Acid; Magnetic Resonance Imaging; Phenotype; Pyruvic Acid; Rats; Rats, Wistar | 2017 |
Simple Monolayer Differentiation of Murine Cardiomyocytes via Nutrient Deprivation-Mediated Activation of β-Catenin.
Topics: Animals; beta Catenin; Calcium; Cell Culture Techniques; Cell Differentiation; Gene Expression; Glucose; Induced Pluripotent Stem Cells; Lactic Acid; Mice; Myocytes, Cardiac; Pluripotent Stem Cells; Pyruvic Acid; Reproducibility of Results; Time Factors; Wnt Signaling Pathway | 2016 |
Assessment of Metformin-Induced Changes in Cardiac and Hepatic Redox State Using Hyperpolarized[1-13C]Pyruvate.
Topics: Animals; Bicarbonates; Carbon Isotopes; Heart; Lactic Acid; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metformin; Myocardium; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar | 2016 |
Sampling Hyperpolarized Molecules Utilizing a 1 Tesla Permanent Magnetic Field.
Topics: Animals; Antibiotics, Antineoplastic; Humans; Lactic Acid; Magnetic Fields; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice, Inbred NOD; Mice, SCID; Prostatic Neoplasms; Pyruvic Acid; Sarcoma; Sirolimus; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Microdialysate concentration changes do not provide sufficient information to evaluate metabolic effects of lactate supplementation in brain-injured patients.
Topics: Brain; Brain Injuries, Traumatic; Critical Care; Energy Metabolism; Glucose; Humans; Lactic Acid; Microdialysis; Oxygen; Pyruvic Acid; Sensitivity and Specificity | 2016 |
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, Animal; Isoenzymes; Kidney Tubules; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Magnetic Resonance Imaging; Male; Predictive Value of Tests; Prognosis; Pyruvic Acid; Rats, Wistar; Reperfusion Injury; Time Factors | 2017 |
Skin glucose metabolism and microvascular blood flow during local insulin delivery and after an oral glucose load.
Topics: Adult; Female; Glucose; Humans; Insulin; Lactic Acid; Male; Microcirculation; Microdialysis; Pyruvic Acid; Regional Blood Flow; Skin; Vasodilation; Young Adult | 2016 |
Reappraisal of the reference levels for energy metabolites in the extracellular fluid of the human brain.
Topics: Adult; Aged; Anesthesia, General; Brain; Energy Metabolism; Extracellular Fluid; Female; Glucose; Glycerol; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Microdialysis; Middle Aged; Monitoring, Intraoperative; Prospective Studies; Pyruvic Acid; Reference Values; Wakefulness; Young Adult | 2017 |
Addition of Sodium Pyruvate to Stored Red Blood Cells Attenuates Liver Injury in a Murine Transfusion Model.
Topics: Animals; Blood Preservation; Blood Transfusion; Disease Models, Animal; Erythrocytes; Hemoglobins; Humans; Interleukin-6; Lactic Acid; Liver Diseases; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxygen; Peroxidase; Pyruvic Acid; Sodium; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha | 2016 |
Nitazoxanide induces in vitro metabolic acidosis in Taenia crassiceps cysticerci.
Topics: Albendazole; Animals; Anticestodal Agents; Antiparasitic Agents; Female; Glucose; Glycolysis; Lactic Acid; Mice; Mice, Inbred BALB C; Nitro Compounds; Pyruvic Acid; Taenia; Thiazoles | 2016 |
Neurochemical changes following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury: A microdialysis study.
Topics: Animals; Brain; Disease Models, Animal; Glucose; Head Injuries, Penetrating; Hypoxia; Lactic Acid; Male; Microdialysis; Pyruvic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic | 2016 |
Hyperoxia results in increased aerobic metabolism following acute brain injury.
Topics: Blood Flow Velocity; Brain; Brain Injuries; Cerebrovascular Circulation; Cytochromes c; Energy Metabolism; Humans; Hyperoxia; Lactic Acid; Microdialysis; Mitochondria; Neurophysiological Monitoring; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Ultrasonography, Doppler, Transcranial | 2017 |
Evidence for impaired glucose metabolism in the striatum, obtained postmortem, from some subjects with schizophrenia.
Topics: Acetyl Coenzyme A; Adult; Blood Glucose; Case-Control Studies; Corpus Striatum; Energy Metabolism; Female; History, 16th Century; History, 17th Century; Humans; Lactic Acid; Male; Middle Aged; Neural Pathways; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Receptors, Muscarinic; Reference Values; Schizophrenia | 2016 |
Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cricetinae; Cricetulus; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Monocarboxylic Acid Transporters; Pyruvic Acid; Solubility | 2017 |
Integration of a 'proton antenna' facilitates transport activity of the monocarboxylate transporter MCT4.
Topics: Animals; Antibodies, Neutralizing; Biological Transport; Carbonic Anhydrase II; Carbonic Anhydrase IV; Gene Expression; Histidine; Lactic Acid; Microinjections; Monocarboxylic Acid Transporters; Muscle Proteins; Oligopeptides; Oocytes; Protein Engineering; Protons; Pyruvic Acid; Rats; Recombinant Fusion Proteins; Xenopus laevis | 2017 |
cGMP-Phosphodiesterase Inhibition Prevents Hypoxia-Induced Cell Death Activation in Porcine Retinal Explants.
Topics: Animals; Antioxidants; Caspase 3; Cell Death; Cyclic GMP; Gene Expression Regulation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Oxidative Stress; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Poly(ADP-ribose) Polymerases; Pyruvic Acid; Retina; Superoxides; Swine; Tissue Culture Techniques | 2016 |
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Female; Gene Knockdown Techniques; Glycine; Glycolysis; Humans; Lactic Acid; Malates; Mass Spectrometry; Metabolic Networks and Pathways; Neoplasm Invasiveness; Nucleotides; Pyruvate Carboxylase; Pyruvic Acid; Serine | 2017 |
Bedside cerebral microdialysis monitoring of delayed cerebral hypoperfusion in comatose patients with poor grade aneurysmal subarachnoid haemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Blood Glucose; Brain; Brain Ischemia; Cohort Studies; Coma; Critical Care; Female; Follow-Up Studies; Humans; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen Consumption; Point-of-Care Testing; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage; Tomography, X-Ray Computed | 2017 |
Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids.
Topics: Amino Acids; Ammonia; Animals; Candida albicans; Carboxylic Acids; Gene Expression Profiling; Host-Pathogen Interactions; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Lactic Acid; Macrophages; Mice; Mutation; Phagosomes; Pyruvic Acid; Transcription Factors | 2016 |
Changes in kidney perfusion and renal cortex metabolism in septic shock: an experimental study.
Topics: Animals; Biomarkers; Female; Glucose; Hypotension; Kidney; Lactic Acid; Laser-Doppler Flowmetry; Pyruvic Acid; Random Allocation; Renal Circulation; Sheep; Shock, Septic | 2017 |
Tween 80 and respiratory growth affect metabolite production and membrane fatty acids in Lactobacillus casei N87.
Topics: Aerobiosis; Amino Acids; Anaerobiosis; Fatty Acids; Lactic Acid; Lacticaseibacillus casei; Metabolic Networks and Pathways; Polysorbates; Pyruvic Acid | 2017 |
Combined Use of S. pombe and L. thermotolerans in Winemaking. Beneficial Effects Determined Through the Study of Wines' Analytical Characteristics.
Topics: Acetic Acid; Amino Acids; Biogenic Amines; Ethanol; Fermentation; Food Microbiology; Gas Chromatography-Mass Spectrometry; Humans; Lactic Acid; Malates; Oenococcus; Pyruvic Acid; Saccharomycetales; Schizosaccharomyces; Wine | 2016 |
Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging.
Topics: Cell Line, Tumor; Fluorodeoxyglucose F18; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Prostatic Neoplasms; Pyruvic Acid | 2016 |
In vivo imaging of the progression of acute lung injury using hyperpolarized [1-
Topics: Acute Lung Injury; Animals; Carbon Isotopes; Disease Progression; Hydrochloric Acid; Image Processing, Computer-Assisted; Inflammation; Lactic Acid; Lung; Magnetic Resonance Imaging; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Trachea | 2017 |
Multi-modality imaging to assess metabolic response to dichloroacetate treatment in tumor models.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Dichloroacetic Acid; Energy Metabolism; Enzyme Inhibitors; Female; Glycolysis; Humans; Lactic Acid; Magnetic Resonance Imaging; Oxidation-Reduction; Oxygen Consumption; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Time Factors; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2016 |
Research on a New Micro-Volume Fluorescence Capillary Biosensor Assay for Sequentially Quantifying Pyruvate and Lactate.
Topics: Biosensing Techniques; Electrophoresis, Capillary; Enzymes, Immobilized; Fluorescence; Humans; L-Lactate Dehydrogenase; Lactic Acid; Pyruvic Acid; Spectrometry, Fluorescence | 2017 |
Lactate and Lactate: Pyruvate Ratio in the Diagnosis and Outcomes of Pediatric Acute Liver Failure.
Topics: Adolescent; Age Factors; Biomarkers; Child; Child, Preschool; Cohort Studies; Female; Humans; Lactic Acid; Liver Failure, Acute; Liver Transplantation; Logistic Models; Male; Mitochondrial Diseases; Prognosis; Pyruvic Acid; Registries; Retrospective Studies; Risk Assessment; Sex Factors; Survival Rate; Treatment Outcome | 2017 |
Tumor stroma interaction is mediated by monocarboxylate metabolism.
Topics: Autocrine Communication; Breast Neoplasms; Carbon Radioisotopes; Cell Communication; Cells, Cultured; Female; Fibroblasts; Glycolysis; Humans; Lactic Acid; Metabolic Networks and Pathways; Pyruvic Acid; Stromal Cells; Tumor Microenvironment | 2017 |
Imaging porcine cardiac substrate selection modulations by glucose, insulin and potassium intervention: A hyperpolarized [1-
Topics: Alanine; Animals; Bicarbonates; Carbon Isotopes; Female; Glucose; Imaging, Three-Dimensional; Insulin; Lactic Acid; Magnetic Resonance Spectroscopy; Monitoring, Physiologic; Potassium; Pyruvic Acid; Sus scrofa | 2017 |
Malignant infarction of the middle cerebral artery in a porcine model. A pilot study.
Topics: Animals; Brain; Disease Models, Animal; Female; Gene Expression; Glucose; Glycerol; Immunohistochemistry; Infarction, Middle Cerebral Artery; Lactic Acid; Middle Cerebral Artery; Oximetry; Oxygen; Partial Pressure; Potassium; Pyruvic Acid; Sulfonylurea Receptors; TRPM Cation Channels | 2017 |
Magnetic Resonance Spectroscopy to Study Glycolytic Metabolism During Autophagy.
Topics: Animals; Autophagy; Carbon Isotopes; Glucose; Glycolysis; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid | 2017 |
Composition of single-step media used for human embryo culture.
Topics: Amino Acids; Animals; Blastocyst; Cell Hypoxia; Cellular Microenvironment; Culture Media; Embryo Culture Techniques; Embryonic Development; Female; Lactic Acid; Male; Mice; Ovulation Induction; Oxygen; Pyruvic Acid; Superovulation; Time Factors | 2017 |
Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells.
Topics: Antineoplastic Agents; Cell Respiration; Cell Survival; Fabaceae; Galactose; Hep G2 Cells; Humans; Lactic Acid; Mannans; Oxidative Phosphorylation; Pyruvic Acid; Seeds; Sulfates | 2017 |
Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke.
Topics: Cerebral Cortex; Cerebral Infarction; Cortical Spreading Depression; Electrocorticography; Female; Glucose; Glutamates; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Intraoperative; Pyruvic Acid; Stroke | 2017 |
Effects of heat stress on the renal and branchial carbohydrate metabolism and antioxidant system of Antarctic fish.
Topics: Animals; Antarctic Regions; Carbohydrate Metabolism; Catalase; Energy Metabolism; Fishes; Gills; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Glycogen; Hot Temperature; Kidney; Lactic Acid; Lipid Peroxidation; Oxidative Stress; Perciformes; Pyruvic Acid; Superoxide Dismutase | 2017 |
Production of d-lactate using a pyruvate-producing Escherichia coli strain.
Topics: Acetyl-CoA Carboxylase; Batch Cell Culture Techniques; Biomass; Culture Media; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Fermentation; Gene Expression Regulation, Bacterial; Lactate Dehydrogenases; Lactic Acid; Metabolic Engineering; Pyruvic Acid | 2017 |
Dynamic
Topics: Animals; Brain; Carbon Isotopes; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Mice; Phantoms, Imaging; Pyruvic Acid; Rats | 2018 |
Metabolic profiling by gas chromatography-mass spectrometry of energy metabolism in high-fat diet-fed obese mice.
Topics: Animals; Blood Chemical Analysis; Citric Acid; Diet, High-Fat; Energy Metabolism; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Lactic Acid; Male; Metabolome; Mice; Mice, Inbred C57BL; Obesity; Pantothenic Acid; Pyruvic Acid; Symporters | 2017 |
The effects of acute renal denervation on kidney perfusion and metabolism in experimental septic shock.
Topics: Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Female; Kidney Cortex; Lactic Acid; Oliguria; Pyruvic Acid; Random Allocation; Renal Artery; Renal Circulation; Sheep; Shock, Septic; Sympathectomy | 2017 |
Early low cerebral blood flow and high cerebral lactate: prediction of delayed cerebral ischemia in subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Cerebrovascular Disorders; Critical Care; Female; Glasgow Outcome Scale; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Predictive Value of Tests; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage; Tomography, X-Ray Computed; Vasospasm, Intracranial | 2018 |
Liver Transplantation for Mitochondrial Respiratory Chain Disorder: A Single-Center Experience and Excellent Marker of Differential Diagnosis.
Topics: Adult; Biomarkers; Diagnosis, Differential; Female; Humans; Lactic Acid; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Mitochondrial Diseases; Pyruvic Acid; Retrospective Studies; ROC Curve; Survival Rate | 2017 |
Should Hyperoxia Be Avoided During Sepsis? An Experimental Study in Ovine Peritonitis.
Topics: Animals; Brain; Cerebrovascular Circulation; Female; Hyperoxia; Lactic Acid; Microcirculation; Models, Animal; Oxygen; Peritonitis; Pulmonary Gas Exchange; Pyruvic Acid; Random Allocation; Renal Circulation; Respiration, Artificial; Sheep; Shock, Septic | 2017 |
Longer duration of operative time enhances healing metabolites and improves patient outcome after Achilles tendon rupture surgery.
Topics: Achilles Tendon; Adult; Cohort Studies; Cross-Sectional Studies; Exercise; Female; Glucose; Glutamic Acid; Glycerol; Heel; Humans; Lactic Acid; Linear Models; Male; Microdialysis; Middle Aged; Operative Time; Patient Reported Outcome Measures; Postoperative Complications; Pyruvic Acid; Retrospective Studies; Rupture; Self Report; Surgical Wound Infection; Tendon Injuries; Treatment Outcome; Venous Thrombosis; Walking | 2018 |
Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury.
Topics: Adenosine; Allopurinol; Animals; Biomarkers; Energy Metabolism; Extracellular Vesicles; Gene Expression; Gene Expression Profiling; Glucose; Glutathione; Insulin; Ion Transport; Kidney; Kidney Transplantation; L-Lactate Dehydrogenase; Lactic Acid; Malondialdehyde; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Organ Preservation; Organ Preservation Solutions; Perfusion; Pyruvic Acid; Raffinose; Rats; Rats, Inbred F344; Rats, Transgenic; Reperfusion Injury | 2017 |
Biological, biochemical and histological features of Bradybaena similaris (Gastropoda: Pulmonata) infected by Heterorabditis indica (Rhabditida: Heterorhabditidae) strain LPP1.
Topics: Animals; Case-Control Studies; Chromatography, High Pressure Liquid; Galactans; Gastropoda; Glucose; Glycogen; Hemolymph; L-Lactate Dehydrogenase; Lactic Acid; Moths; Pyruvic Acid; Rhabditoidea | 2017 |
Evidence for Rapid Oxidative Phosphorylation and Lactate Fermentation in Motile Human Sperm by Hyperpolarized
Topics: Carbohydrate Metabolism; Carbon-13 Magnetic Resonance Spectroscopy; Fermentation; Humans; Lactic Acid; Male; Oxidative Phosphorylation; Pyruvic Acid; Sperm Motility; Spermatozoa | 2017 |
The metabolic effects of diuron in the rat liver.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Diuron; Energy Metabolism; Fructose; Gluconeogenesis; Glucose; Herbicides; Lactic Acid; Liver; Male; Mitochondria, Liver; Pyruvic Acid; Rats, Wistar | 2017 |
Cancer recurrence monitoring using hyperpolarized [1-
Topics: Animals; Carbon Isotopes; Female; Glycolysis; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Neoplasm Recurrence, Local; Neoplasm Transplantation; Proto-Oncogene Proteins c-myc; Pyruvic Acid; Tumor Burden | 2017 |
Susceptibility-induced distortion correction in hyperpolarized echo planar imaging.
Topics: Algorithms; Aorta, Abdominal; Bicarbonates; Echo-Planar Imaging; Heart; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lactic Acid; Liver; Models, Statistical; Phantoms, Imaging; Pyruvic Acid; Reproducibility of Results; Signal-To-Noise Ratio | 2018 |
Intraperitoneal lactate/pyruvate ratio and the level of glucose and glycerol concentration differ between patients surgically treated for upper and lower perforations of the gastrointestinal tract: a pilot study.
Topics: Aged; Aged, 80 and over; Female; Glucose; Glycerol; Humans; Intestinal Perforation; Lactic Acid; Male; Microdialysis; Middle Aged; Peritoneum; Peritonitis; Pilot Projects; Postoperative Complications; Postoperative Period; Pyruvic Acid | 2017 |
Lactate oxidation facilitates growth of Mycobacterium tuberculosis in human macrophages.
Topics: Carbon Cycle; Cells, Cultured; Gluconeogenesis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Macrophages; Mycobacterium tuberculosis; Oxidation-Reduction; Pyruvic Acid; Tuberculosis | 2017 |
Metabolic engineering of CHO cells for the development of a robust protein production platform.
Topics: Animals; Antibodies, Monoclonal; Bioreactors; Carbon; CHO Cells; Citric Acid Cycle; Cricetinae; Cricetulus; Cytoplasm; Cytosol; Energy Metabolism; Gene Dosage; Glucose; Glutamine; Glycosylation; Lactates; Lactic Acid; Metabolic Engineering; Mitochondria; Oligonucleotides; Oxidation-Reduction; Polysaccharides; Pyruvate Carboxylase; Pyruvic Acid; Saccharomyces cerevisiae | 2017 |
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.
Topics: Acrylates; Animals; Anion Transport Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Drosophila melanogaster; Drosophila Proteins; Genotype; Glycolysis; Humans; Intestinal Mucosa; Intestines; Lactic Acid; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Monocarboxylic Acid Transporters; Phenotype; Pyruvic Acid; Receptors, G-Protein-Coupled; RNA Interference; Signal Transduction; Stem Cells; Time Factors; Tissue Culture Techniques; Transfection | 2017 |
Oxygen-Inducible Conversion of Lactate to Acetate in Heterofermentative Lactobacillus brevis ATCC 367.
Topics: Acetates; Aerobiosis; Bacterial Proteins; Fermentation; Glucose; L-Lactate Dehydrogenase; Lactic Acid; Levilactobacillus brevis; Oxygen; Pyruvate Oxidase; Pyruvic Acid | 2017 |
Levels of L-malate and other low molecular weight metabolites in spores of Bacillus species and Clostridium difficile.
Topics: Bacillus; Clostridioides difficile; Lactic Acid; Magnetic Resonance Spectroscopy; Malates; Pyruvic Acid; Spores, Bacterial | 2017 |
A benzimidazole derivative (RCB15) in vitro induces the alternative energetic metabolism and glycolysis in Taenia crassiceps cysticerci.
Topics: Albendazole; Animals; Anticestodal Agents; Benzimidazoles; Cysticercus; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Glycolysis; Lactic Acid; Oxidation-Reduction; Pyruvic Acid | 2017 |
Dynamic nuclear polarization facilitates monitoring of pyruvate metabolism in
Topics: Alanine; Algorithms; Animals; Carbon Dioxide; Carbon Isotopes; Cells, Immobilized; Energy Metabolism; Gastrointestinal Tract; HEK293 Cells; Hep G2 Cells; Humans; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Trypanosoma brucei brucei; Trypanosomiasis; Tsetse Flies | 2017 |
Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized
Topics: Animals; Brain; Carbon-13 Magnetic Resonance Spectroscopy; Glucose; Glycolysis; Lactic Acid; Mice; Pyruvic Acid | 2017 |
Detection of metabolic pattern following decompressive craniectomy in severe traumatic brain injury: A microdialysis study.
Topics: Brain Injuries, Traumatic; Cerebrovascular Circulation; Decompressive Craniectomy; Female; Glasgow Outcome Scale; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Mitochondrial Diseases; Pyruvic Acid; Treatment Outcome | 2017 |
PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy.
Topics: Animals; Citric Acid Cycle; Fatty Acids; Female; Glucose; Lactic Acid; Mice; Mice, Inbred C57BL; Myocardium; Pregnancy; Progesterone; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid | 2017 |
The rate of lactate production from glucose in hearts is not altered by per-deuteration of glucose.
Topics: Animals; Citric Acid Cycle; Deuterium; Fructose-Bisphosphate Aldolase; Glucose; Glycolysis; Isotope Labeling; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2017 |
The effects of the obesogen tributyltin on the metabolism of Sertoli cells cultured ex vivo.
Topics: Animals; Cell Proliferation; Cells, Cultured; Fertility; Glucose; Glycolysis; Inhibins; Lactic Acid; Male; Primary Cell Culture; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Androgen; Sertoli Cells; Trialkyltin Compounds | 2018 |
Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome.
Topics: Animals; Blastocyst; Cattle; Embryonic Development; Endometrium; Female; Gene Expression Regulation, Developmental; Glucose; Lactation; Lactic Acid; Metabolism; Parity; Pregnancy; Progesterone; Pyruvic Acid; RNA; Superovulation; Transcriptome; Uterus | 2017 |
Nicotine Adenine Dinucleotides: The Redox Currency of the Cell.
Topics: Humans; Lactic Acid; NAD; Oxidation-Reduction; Pyruvic Acid | 2018 |
Impaired p53/CEP-1 is associated with lifespan extension through an age-related imbalance in the energy metabolism of C. elegans.
Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Energy Metabolism; Lactic Acid; Longevity; Mitochondria; Mutation; Oxygen Consumption; Pyruvic Acid; Signal Transduction; Tumor Suppressor Protein p53 | 2017 |
Comparative genomics and transcriptome analysis of Lactobacillus rhamnosus ATCC 11443 and the mutant strain SCT-10-10-60 with enhanced L-lactic acid production capacity.
Topics: Gene Expression Regulation, Bacterial; Genome, Bacterial; Genomics; Lactic Acid; Lacticaseibacillus rhamnosus; Metabolic Engineering; Mutation; Pyruvic Acid; Transcriptome | 2018 |
Multi-timescale analysis of a metabolic network in synthetic biology: a kinetic model for 3-hydroxypropionic acid production via beta-alanine.
Topics: Biosynthetic Pathways; Computer Simulation; Kinetics; Lactic Acid; Mathematical Concepts; Metabolic Networks and Pathways; Models, Biological; Pyruvic Acid; Saccharomyces cerevisiae; Synthetic Biology | 2018 |
Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms.
Topics: Adenocarcinoma, Mucinous; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Gene Expression Regulation, Neoplastic; Humans; Lactic Acid; Pancreas; Pancreatic Neoplasms; Pyruvic Acid; Retrospective Studies; Transcriptome | 2018 |
A referenceless Nyquist ghost correction workflow for echo planar imaging of hyperpolarized [1-
Topics: Animals; Carbon Isotopes; Echo-Planar Imaging; Female; Image Processing, Computer-Assisted; Lactic Acid; Mice, Inbred C57BL; Phantoms, Imaging; Pyruvic Acid; Reference Standards; Signal Processing, Computer-Assisted; Signal-To-Noise Ratio | 2018 |
High-resolution hyperpolarized metabolic imaging of the rat heart using k-t PCA and k-t SPARSE.
Topics: Animals; Area Under Curve; Bicarbonates; Carbon Isotopes; Computer Simulation; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Myocardium; Principal Component Analysis; Pyruvic Acid; Rats, Sprague-Dawley; Signal-To-Noise Ratio | 2018 |
Efficient bioconversion of organic wastes to high optical activity of l-lactic acid stimulated by cathode in mixed microbial consortium.
Topics: Biomass; Biotechnology; Electrodes; Fermentation; Lactic Acid; Microbial Consortia; Optical Rotation; Pyruvic Acid; Sewage; Waste Disposal, Fluid; Waste Products | 2018 |
Direct assessment of renal mitochondrial redox state using hyperpolarized
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Catalysis; Ketones; Kidney; Lactic Acid; Liver; Magnetic Resonance Imaging; Metformin; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2018 |
Catabolite repression in Campylobacter jejuni correlates with intracellular succinate levels.
Topics: Bacterial Proteins; Campylobacter jejuni; Carbon; Catabolite Repression; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Lactic Acid; Pyruvic Acid; Serine; Succinic Acid; Transcription Factors | 2018 |
Tourniquet time in total knee arthroplasty.
Topics: Aged; Arthroplasty, Replacement, Knee; Asparagine; Creatine Kinase; Female; Glucose; Glycerol; Humans; Ischemia; L-Lactate Dehydrogenase; Lactic Acid; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Prospective Studies; Pyruvic Acid; Time Factors; Tourniquets; Transaminases | 2018 |
Simultaneous multislice acquisition without trajectory modification for hyperpolarized
Topics: Animals; Carbon Isotopes; Heart; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Myocardium; Phantoms, Imaging; Pyruvic Acid; Signal-To-Noise Ratio; Swine | 2018 |
Placental physiology monitored by hyperpolarized dynamic
Topics: Animals; Bicarbonates; Carbon Isotopes; Disease Models, Animal; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Monitoring, Physiologic; Placenta; Pre-Eclampsia; Pregnancy; Pyruvic Acid; Rats; Rats, Wistar | 2018 |
Investigation of biomarkers alterations after an acute tissue trauma in human trapezius muscle, using microdialysis.
Topics: Adult; Biomarkers; Blood Flow Velocity; Cross-Sectional Studies; Extracellular Fluid; Female; Glucose; Glutamic Acid; Glycerol; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Musculoskeletal Pain; Pain Measurement; Pain Threshold; Pressure; Pyruvic Acid; Superficial Back Muscles | 2018 |
High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-
Topics: Adenocarcinoma; Alanine; Animals; Carbon Isotopes; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Male; Mice; Neoplasm Transplantation; Prostatic Neoplasms; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors; Transgenes | 2018 |
Analysis of
Topics: Animals; Carbon Isotopes; Carbon Radioisotopes; Injections; Isotope Labeling; Lactic Acid; Lymphoma; Mice, Inbred C57BL; Pyruvic Acid; Tissue Distribution | 2018 |
Target and untargeted GC-MS based metabolomic study of mouse optic nerve and its potential in the study of neurological visual diseases.
Topics: Animals; Biomarkers; Disease Models, Animal; Eye; Female; Gas Chromatography-Mass Spectrometry; Lactic Acid; Male; Metabolomics; Mice; Optic Nerve; Optic Nerve Diseases; Pyruvic Acid | 2018 |
Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity.
Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cell Survival; Chemokines; Citric Acid Cycle; Deoxyglucose; Female; Galactose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interferon-gamma; Janus Kinases; Lactic Acid; Macrophage Activation; Macrophages; Metabolome; Mice; Mitochondria; Nitric Oxide; Proto-Oncogene Proteins c-akt; Pyruvic Acid; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; STAT1 Transcription Factor | 2018 |
Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach.
Topics: Acute Lung Injury; Animals; Biomarkers; Carbon Isotopes; Disease Models, Animal; Gene Expression; Humans; Hyalin; Hydrochloric Acid; Intercellular Adhesion Molecule-1; Lactic Acid; Lung; Magnetic Resonance Imaging; Male; Peroxidase; Pneumonia; Positive-Pressure Respiration; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Respiration, Artificial; Respiratory Distress Syndrome | 2018 |
In vivo hyperpolarization transfer in a clinical MRI scanner.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Lactic Acid; Liver; Phantoms, Imaging; Pyruvic Acid; Rats; Signal Processing, Computer-Assisted | 2018 |
Oligodendrocytes in the Mouse Corpus Callosum Maintain Axonal Function by Delivery of Glucose.
Topics: Action Potentials; Animals; Astrocytes; Axons; Connexins; Corpus Callosum; Dialysis; Glucose; Lactic Acid; Lysine; Mice, Knockout; Monocarboxylic Acid Transporters; Neuroglia; Oligodendroglia; Pyruvic Acid | 2018 |
Cerebral Metabolic Changes Related to Oxidative Metabolism in a Model of Bacterial Meningitis Induced by Lipopolysaccharide.
Topics: Animals; Cerebrum; Disease Models, Animal; Female; Lactic Acid; Lipopolysaccharides; Meningitis, Bacterial; Microdialysis; Mitochondrial Diseases; Neurophysiological Monitoring; Pyruvic Acid; Swine | 2018 |
Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism.
Topics: Animals; Antineoplastic Agents; Carbon; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Citric Acid Cycle; Female; Glycolysis; Head and Neck Neoplasms; Humans; Lactic Acid; Mice; Mice, Nude; Oxidative Stress; Pentose Phosphate Pathway; Pyruvic Acid; Tumor Suppressor Protein p53 | 2018 |
The urinary organic acids profile in single large-scale mitochondrial DNA deletion disorders.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase, Long-Chain; Adolescent; Child; Child, Preschool; Congenital Bone Marrow Failure Syndromes; DNA, Mitochondrial; Fumarates; Glutarates; Humans; Hydroxybutyrates; Infant; Kearns-Sayre Syndrome; Lactic Acid; Lipid Metabolism, Inborn Errors; Mitochondrial Diseases; Muscular Diseases; Pyruvic Acid; Retrospective Studies; Valerates | 2018 |
The relationship between intracranial pressure and lactate/pyruvate ratio in patients with subarachnoid haemorrhage.
Topics: Aneurysm, Ruptured; Brain; Humans; Intracranial Aneurysm; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Microdialysis; Monitoring, Physiologic; Pyruvic Acid; Subarachnoid Hemorrhage | 2018 |
Using a local low rank plus sparse reconstruction to accelerate dynamic hyperpolarized
Topics: Algorithms; Animals; Computer Simulation; Image Processing, Computer-Assisted; Lactic Acid; Magnetic Resonance Imaging; Mice; Neoplasms, Experimental; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution; Urea | 2018 |
Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Female; Gene Silencing; Glucose; Glycolysis; Humans; Ion Transport; Lactic Acid; Male; MCF-7 Cells; Mice; Mice, Inbred C57BL; Mitochondria; Monocarboxylic Acid Transporters; Muscle Proteins; Neoplasm Transplantation; Oxygen; Pyruvic Acid; Radiation-Sensitizing Agents; Rats; RNA, Small Interfering; Symporters; Thiophenes; Uracil; Xenopus laevis | 2018 |
Performance during a strenuous swimming session is associated with high blood lactate: pyruvate ratio and hypoglycemia in fasted rats.
Topics: Animals; Blood Glucose; Fasting; Hypoglycemia; Lactic Acid; Liver; Male; Perfusion; Physical Conditioning, Animal; Pyruvic Acid; Rats; Rats, Wistar; Swimming; Time Factors | 2018 |
Overestimation of cardiac lactate production caused by liver metabolism of hyperpolarized [1-
Topics: Animals; Carbon Isotopes; Female; Heart; Lactic Acid; Liver; Magnetic Resonance Imaging; Myocardium; Phantoms, Imaging; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2018 |
Unveiling the oxidative metabolism of Achatina fulica (Mollusca: Gastropoda) experimentally infected to Angiostrongylus cantonensis (Nematoda: Metastrongylidae).
Topics: Angiostrongylus cantonensis; Animals; Carboxylic Acids; Chromatography, High Pressure Liquid; Glucose; Hemolymph; Hexokinase; L-Lactate Dehydrogenase; Lactic Acid; Oxalic Acid; Oxidative Stress; Parasite Load; Polysaccharides; Pyruvic Acid; Snails | 2018 |
[Characterization of D-lactate dehydrogenase isozymes from a D-lactic acid producing bacterium Sporolactobacillus inulinus].
Topics: Bacillales; Bacterial Proteins; Enzyme Stability; Glucose; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lactate Dehydrogenases; Lactic Acid; Pyruvic Acid | 2016 |
Androgen Receptor Signaling in Castration-Resistant Prostate Cancer Alters Hyperpolarized Pyruvate to Lactate Conversion and Lactate Levels In Vivo.
Topics: Animals; Disease Models, Animal; Disease Progression; Heterografts; Humans; Image Enhancement; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, SCID; Neoplasm Invasiveness; Prostate; Prostatic Neoplasms, Castration-Resistant; Pyruvic Acid; Receptors, Androgen; Signal Transduction; Tumor Cells, Cultured | 2019 |
NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia.
Topics: Acetic Acid; Animals; Biomarkers; Blood Glucose; Brain Ischemia; Cerebrovascular Disorders; Creatine; Glycolysis; Ischemic Preconditioning; Ketone Bodies; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolome; Pyruvic Acid; Rats; Rats, Wistar; Reperfusion Injury; Triglycerides | 2018 |
Acetyl-CoA from inflammation-induced fatty acids oxidation promotes hepatic malate-aspartate shuttle activity and glycolysis.
Topics: Acetyl Coenzyme A; Acetylation; Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Carbon Isotopes; Fatty Acids; Glycolysis; Inflammation; Lactic Acid; Lipopolysaccharides; Liver; Malate Dehydrogenase; Malates; Mitochondria, Liver; Oxidation-Reduction; Palmitic Acid; Pyruvic Acid; Stress, Physiological; Sus scrofa; Swine | 2018 |
Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells.
Topics: Caprylates; Hepatocytes; Humans; Lactic Acid; Non-alcoholic Fatty Liver Disease; Pyruvic Acid; Transcriptome | 2018 |
Metabolomic and proteomic analysis of D-lactate-producing Lactobacillus delbrueckii under various fermentation conditions.
Topics: Adenosine Triphosphate; Chromatography, Liquid; Fermentation; Gas Chromatography-Mass Spectrometry; Glycolysis; Hydrolysis; Industrial Microbiology; Lactic Acid; Lactobacillus delbrueckii; Metabolomics; Nitrogen; Nucleotides; Peptides; Phenotype; Polyesters; Proteomics; Pyruvic Acid; Stress, Mechanical; Tandem Mass Spectrometry | 2018 |
Hypoxia induces lactate secretion and glycolytic efflux by downregulating mitochondrial pyruvate carrier levels in human umbilical vein endothelial cells.
Topics: Acrylates; Cell Hypoxia; Glycolysis; Human Umbilical Vein Endothelial Cells; Humans; Lactate Dehydrogenases; Lactic Acid; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Monocarboxylic Acid Transporters; Oxidative Phosphorylation; Oxygen; Phosphofructokinase-2; Pyruvic Acid | 2018 |
Molecular detection of inflammation in cell models using hyperpolarized
Topics: Animals; Biotransformation; Carbon Isotopes; Cell Line; Glycolysis; Immunologic Factors; Inflammation; Isotope Labeling; Lactic Acid; Lipopolysaccharides; Macrophage Activation; Macrophages; Magnetic Resonance Spectroscopy; Mice; Pyruvic Acid | 2018 |
Real-time ex-vivo measurement of brain metabolism using hyperpolarized [1-
Topics: Animals; Bicarbonates; Brain; Carbon Isotopes; Female; Lactic Acid; Magnetic Resonance Spectroscopy; Movement; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 2018 |
Identification and Characterization of l-Malate Dehydrogenases and the l-Lactate-Biosynthetic Pathway in Leuconostoc mesenteroides ATCC 8293.
Topics: Bacterial Proteins; Biosynthetic Pathways; Enzyme Stability; Kinetics; Lactic Acid; Leuconostoc mesenteroides; Malate Dehydrogenase; Malates; Pyruvic Acid; Substrate Specificity | 2018 |
MicroRNA-31-5p enhances the Warburg effect via targeting FIH.
Topics: Animals; Apoptosis; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Mixed Function Oxygenases; Pyruvic Acid; Repressor Proteins; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Suppression of PDHX by microRNA-27b deregulates cell metabolism and promotes growth in breast cancer.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citric Acid; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Lactic Acid; MCF-7 Cells; MicroRNAs; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Survival Analysis | 2018 |
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors.
Topics: A549 Cells; Acetyl Coenzyme A; Anilides; Antineoplastic Agents; Chromatography, Liquid; Citric Acid Cycle; Cytosol; Dichloroacetic Acid; Gene Expression Regulation; Glucose; Glycolysis; Humans; Isoenzymes; Lactic Acid; Mitochondria; Oxidative Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Tandem Mass Spectrometry | 2018 |
Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep.
Topics: Animals; Glutamic Acid; Homovanillic Acid; Humans; Lactic Acid; Metabolomics; Mice; Motor Cortex; Prefrontal Cortex; Pyruvic Acid; Sleep; Sleep Deprivation; Tryptophan; Uridine; Wakefulness | 2018 |
Identification of Intracellular and Extracellular Metabolites in Cancer Cells Using
Topics: Animals; Cell Line, Tumor; Female; Lactic Acid; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Mice; Pyruvic Acid | 2018 |
Pyruvate Kinase Muscle-1 Expression Appears to Drive Lactogenic Behavior in CHO Cell Lines, Triggering Lower Viability and Productivity: A Case Study.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; CRISPR-Cas Systems; Erythrocytes; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Liver; Pyruvate Kinase; Pyruvic Acid | 2019 |
Hyperpolarized
Topics: Algorithms; Animals; Carbon-13 Magnetic Resonance Spectroscopy; Imaging, Three-Dimensional; Lactic Acid; Mice; Phantoms, Imaging; Pyruvic Acid; Signal Processing, Computer-Assisted; Spin Labels | 2018 |
Lactic acid fermentation is the main aerobic metabolic pathway in Enterococcus faecalis metabolizing a high concentration of glycerol.
Topics: Acetic Acid; Acetoin; Culture Media; Enterococcus faecalis; Ethanol; Fermentation; Glucose; Glycerol; Industrial Microbiology; L-Lactate Dehydrogenase; Lactic Acid; Metabolic Networks and Pathways; Oxygen; Pyruvic Acid | 2018 |
cAMP Receptor Protein of Salmonella enterica Serovar Typhimurium Modulate Glycolysis in Macrophages to Induce Cell Apoptosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line; Cyclic AMP Receptor Protein; Glycolysis; Hexokinase; Lactic Acid; Macrophages; Mice; Pyruvic Acid; RAW 264.7 Cells; Salmonella typhimurium | 2019 |
Cytotoxicity of xyloglucan from Copaifera langsdorffii and its complex with oxovanadium (IV/V) on B16F10 cells.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Fabaceae; Glucans; Lactic Acid; Melanoma, Experimental; Mice; Mitochondria; Organometallic Compounds; Pyruvic Acid; Vanadates; Xylans | 2019 |
Cafeteria Diet Feeding in Young Rats Leads to Hepatic Steatosis and Increased Gluconeogenesis under Fatty Acids and Glucagon Influence.
Topics: Animals; Diet; Energy Intake; Fatty Acids; Fatty Liver; Feeding Behavior; Glucagon; Gluconeogenesis; Glucose; Lactic Acid; Male; Obesity; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar | 2018 |
Small-Scale Colorimetric Assays of Intracellular Lactate and Pyruvate in the Nematode Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Colorimetry; Lactic Acid; Mitochondria; Pyruvic Acid | 2018 |
Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients.
Topics: Artifacts; Bicarbonates; Brain; Brain Neoplasms; Calibration; Carbon Isotopes; Carbon-13 Magnetic Resonance Spectroscopy; Echo-Planar Imaging; Humans; Image Enhancement; Image Processing, Computer-Assisted; Lactic Acid; Male; Molecular Imaging; Phantoms, Imaging; Prostate; Prostatic Neoplasms; Pyruvic Acid; Signal-To-Noise Ratio | 2019 |
Trypanosoma brucei aquaglyceroporins mediate the transport of metabolic end-products: Methylglyoxal, D-lactate, L-lactate and acetate.
Topics: Acetates; Aquaglyceroporins; Biological Transport; Glycerol; Glycolysis; Lactic Acid; Pyruvaldehyde; Pyruvic Acid; Stereoisomerism; Trypanosoma brucei brucei | 2018 |
Hydrogen production by Sulfurospirillum species enables syntrophic interactions of Epsilonproteobacteria.
Topics: Acetic Acid; Anaerobiosis; Campylobacteraceae; Coculture Techniques; Fermentation; Fumarates; Hydrogen; Kinetics; Lactic Acid; Methanococcus; Oxidation-Reduction; Pyruvic Acid; Succinic Acid; Symbiosis | 2018 |
Promotion of Calcium/Calmodulin-Dependent Protein Kinase 4 by GLUT1-Dependent Glycolysis in Systemic Lupus Erythematosus.
Topics: Adult; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Case-Control Studies; CD4-Positive T-Lymphocytes; Cell Differentiation; Female; Fructosediphosphates; Fructosephosphates; Glucose Transporter Type 1; Glucose-6-Phosphate; Glycolysis; Humans; Immunologic Memory; Interleukin-17; Lactic Acid; Lupus Erythematosus, Systemic; Male; Metabolome; Metabolomics; Mice; Mice, Inbred MRL lpr; Middle Aged; Pentose Phosphate Pathway; Protein Kinase Inhibitors; Pyruvic Acid; Sulfonamides; Th17 Cells | 2019 |
Simultaneous determination of lactic acid and pyruvic acid in tissue and cell culture media by gas chromatography after in situ derivatization-ultrasound-assisted emulsification microextraction.
Topics: Animals; Cells, Cultured; Chromatography, Gas; Citric Acid Cycle; Culture Media; Emulsions; Lactic Acid; Limit of Detection; Mice; Mitochondrial Diseases; Pyruvic Acid; Reproducibility of Results; Sonication | 2019 |
Roles of d-Lactate Dehydrogenases in the Anaerobic Growth of
Topics: Anaerobiosis; Bacterial Proteins; Cyclic AMP Receptor Protein; Electron Transport; Fermentation; Gene Expression Regulation, Bacterial; Lactate Dehydrogenases; Lactic Acid; Oxidation-Reduction; Pyruvic Acid; Shewanella; Sugars | 2019 |
Monitoring Age-Related Changes in the Lactate/Pyruvate Ratio Using a Colorimetric Assay in a C. elegans Model of Increased Life Span.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Colorimetry; Energy Metabolism; Humans; Lactic Acid; Longevity; Mutation; Pyruvic Acid; Tumor Suppressor Protein p53 | 2019 |
Hyperpolarized [1-
Topics: Alanine; Animals; Blood Glucose; Citric Acid Cycle; Fatty Acids; Female; Glucagon; Insulin; Lactic Acid; Liver Diseases; Magnetic Resonance Imaging; Pyruvic Acid; Swine | 2018 |
Oral nitazoxanide treatment of experimental neurocysticercosis induces gluconeogenesis in Taenia crassiceps cysticerci.
Topics: Administration, Oral; Animals; Anthelmintics; Chromatography, High Pressure Liquid; Cysticercus; Energy Metabolism; Fatty Acids; Gluconeogenesis; Glucose; Lactic Acid; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Neurocysticercosis; Nitro Compounds; Oxaloacetic Acid; Oxidation-Reduction; Pyruvic Acid; Taenia; Thiazoles | 2019 |
Hyperpolarized [1-13C] pyruvate MR spectroscopy detect altered glycolysis in the brain of a cognitively impaired mouse model fed high-fat diet.
Topics: Animals; Blood-Brain Barrier; Brain; Carbon Isotopes; Cognitive Dysfunction; Diet, High-Fat; Disease Models, Animal; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice, Inbred ICR; Perfusion; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2018 |
[The role of fatty acids, water-soluble vitamins, calcium, phosphorus in maintaining carbohydrate metabolism in youth population of two different climatic geographic regions].
Topics: Adolescent; Adult; Calcium; Carbohydrate Metabolism; Cold Climate; Fatty Acids; Female; Humans; Lactic Acid; Male; Minerals; Phosphorus; Pyruvic Acid; Russia; Vitamins; Young Adult | 2016 |
Feasibility of lung microdialysis to assess metabolism during clinical ex vivo lung perfusion.
Topics: Adult; Feasibility Studies; Glucose; Glutamic Acid; Humans; In Vitro Techniques; Lactic Acid; Lung; Lung Transplantation; Microdialysis; Middle Aged; Perfusion; Predictive Value of Tests; Pyruvic Acid; Treatment Outcome; Young Adult | 2019 |
A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures.
Topics: Animals; Bioreactors; Cell Line, Tumor; Cell Survival; Collagen; Contrast Media; Diffusion; Disease Progression; Equipment Design; Female; Gels; Glucose; Lactic Acid; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; NAD; Optical Imaging; Printing, Three-Dimensional; Pyruvic Acid; Temperature | 2019 |
GPR31-dependent dendrite protrusion of intestinal CX3CR1
Topics: Animals; Bacteria; Cell Surface Extensions; CX3C Chemokine Receptor 1; Female; HEK293 Cells; Humans; Intestine, Small; Lactic Acid; Lactobacillus helveticus; Male; Methanol; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Pyruvic Acid; Receptors, G-Protein-Coupled; Salmonella | 2019 |
FOXK1 and FOXK2 regulate aerobic glycolysis.
Topics: 3T3 Cells; Aerobiosis; Animals; Cells, Cultured; Female; Forkhead Transcription Factors; Glycolysis; Humans; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle Fibers, Skeletal; Oxidation-Reduction; Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase (Lipoamide)-Phosphatase; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2019 |
Analysis of metabolic flux in felid spermatozoa using metabolomics and 13C-based fluxomics†.
Topics: Acinonyx; Animals; Animals, Domestic; Carbon Isotopes; Cats; Citric Acid Cycle; Energy Metabolism; Felidae; Glycolysis; Lactic Acid; Male; Metabolomics; Pyruvic Acid; Semen Analysis; Spermatozoa | 2019 |
Hyperpolarized MRI for Studying Tumor Metabolism.
Topics: Animals; Biomarkers; Data Analysis; Disease Models, Animal; Energy Metabolism; Humans; Kinetics; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Models, Biological; Neoplasms; Pyruvic Acid | 2019 |
Novel pharmacological effects of poly (ADP-ribose) polymerase inhibitor rucaparib on the lactate dehydrogenase pathway.
Topics: Cell Line, Tumor; Female; Humans; Indoles; L-Lactate Dehydrogenase; Lactic Acid; Ovarian Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Pyruvic Acid; Signal Transduction | 2019 |
Biomarkers and clinical rating scales for sodium pyruvate therapy in patients with mitochondrial disease.
Topics: Acidosis, Lactic; Adolescent; Adult; Biomarkers; Female; Fibroblast Growth Factors; Growth Differentiation Factor 15; Humans; Lactic Acid; Male; MELAS Syndrome; Middle Aged; Mitochondria; Mitochondrial Diseases; Prospective Studies; Pyruvic Acid; Sodium; Young Adult | 2019 |
Effects of excitation angle strategy on quantitative analysis of hyperpolarized pyruvate.
Topics: Carbon Isotopes; Computer Simulation; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Reproducibility of Results; Signal Processing, Computer-Assisted | 2019 |
Effects of deuteration on transamination and oxidation of hyperpolarized
Topics: Alanine; Alanine Transaminase; Amination; Animals; Carbon Isotopes; Deuterium; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Water | 2019 |
Imaging Hyperpolarized Pyruvate and Lactate after Blood-Brain Barrier Disruption with Focused Ultrasound.
Topics: Animals; Blood-Brain Barrier; Carbon-13 Magnetic Resonance Spectroscopy; Lactic Acid; Magnetic Resonance Imaging, Interventional; Metabolic Networks and Pathways; Mice; Microscopy, Polarization; Pyruvic Acid; Ultrasonic Waves | 2019 |
Electrolyzing lactic acid in situ in fermentation broth to produce pyruvic acid in electrolysis cell.
Topics: Culture Media; Electrolysis; Hydrogen-Ion Concentration; Lactic Acid; Pyruvic Acid | 2019 |
A highly selective amperometric biosensor array for the simultaneous determination of glutamate, glucose, choline, acetylcholine, lactate and pyruvate.
Topics: Acetylcholine; Biosensing Techniques; Buffers; Choline; Electrochemical Techniques; Electrodes; Enzymes, Immobilized; Glucose; Glutamic Acid; Hydrogen-Ion Concentration; Lactic Acid; Limit of Detection; Osmolar Concentration; Pyruvic Acid; Reproducibility of Results | 2019 |
The Importance of Probe Location for the Interpretation of Cerebral Microdialysis Data in Subarachnoid Hemorrhage Patients.
Topics: Aged; Aneurysm, Ruptured; Brain; Brain Edema; Brain Ischemia; Cohort Studies; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hydrocephalus; Intracranial Aneurysm; Lactic Acid; Male; Microdialysis; Middle Aged; Mitochondria; Monitoring, Physiologic; Prospective Studies; Pyruvic Acid; Retrospective Studies; Stress, Physiological; Subarachnoid Hemorrhage | 2020 |
The quantitative relationship between isotopic and net contributions of lactate and glucose to the tricarboxylic acid (TCA) cycle.
Topics: Carbon Isotopes; Citric Acid Cycle; Glucose; HeLa Cells; Humans; Isotope Labeling; Lactic Acid; Pyruvic Acid | 2019 |
Metabolomics Analysis in Serum from Patients with Colorectal Polyp and Colorectal Cancer by
Topics: Acetates; Amino Acids; Biomarkers; Citrates; Colonic Polyps; Colorectal Neoplasms; Glycerol; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Metabolome; Pyruvic Acid | 2019 |
Determination of Pyruvate Metabolic Fates Modulates Head and Neck Tumorigenesis.
Topics: Animals; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Glycolysis; Heterografts; Humans; L-Lactate Dehydrogenase; Lactic Acid; Mice; Mitochondria; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Squamous Cell Carcinoma of Head and Neck | 2019 |
Pyruvate and lactate as local prognostic biomarkers of patient outcome after achilles tendon rupture.
Topics: Achilles Tendon; Adult; Biomarkers; Female; Humans; Lactic Acid; Male; Middle Aged; Patient Reported Outcome Measures; Prognosis; Prospective Studies; Pyruvic Acid; Rupture; Tendon Injuries | 2019 |
Detection of lung transplant rejection in a rat model using hyperpolarized [1-
Topics: Animals; Biomarkers; Carbon Isotopes; Graft Rejection; Lactic Acid; Lung; Lung Transplantation; Magnetic Resonance Imaging; Male; Models, Animal; Molecular Imaging; Organ Size; Peroxidase; Pyruvic Acid; Rats, Wistar; T-Lymphocytes; Tomography, X-Ray Computed | 2019 |
Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Glycolysis; Heterografts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pancreatic Neoplasms; Pyruvic Acid | 2019 |
High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury.
Topics: Adult; Arterial Pressure; Blood Glucose; Blood Pressure; Brain; Brain Injuries, Traumatic; Cerebrovascular Circulation; Female; Glasgow Outcome Scale; Glucose; Homeostasis; Humans; Hyperglycemia; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Prognosis; Pyruvic Acid; Radial Artery; Retrospective Studies; Sweden; Young Adult | 2019 |
Cheese whey to biohydrogen and useful organic acids: A non-pathogenic microbial treatment by L. acidophilus.
Topics: Biofuels; Bioreactors; Butyrates; Cheese; Escherichia coli; Fermentation; Food Microbiology; Food Technology; Formates; Hexoses; Hydrogen; Hydrogen-Ion Concentration; Lactic Acid; Lacticaseibacillus casei; Lacticaseibacillus paracasei; Lactobacillus acidophilus; Lactococcus lactis; Lipids; Propionates; Pyruvic Acid; Whey | 2019 |
Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in Toxoplasma gondii.
Topics: Alanine; Carbon; Homeostasis; Lactic Acid; Metabolomics; Protozoan Proteins; Pyruvic Acid; Toxoplasma | 2019 |
Protocolized Brain Oxygen Optimization in Subarachnoid Hemorrhage.
Topics: Aged; Brain; Carbon Dioxide; Cerebrovascular Circulation; Clinical Protocols; Cohort Studies; Female; Glasgow Outcome Scale; Glucose; Humans; Hypoxia, Brain; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen; Oxygen Inhalation Therapy; Partial Pressure; Pyruvic Acid; Respiration, Artificial; Subarachnoid Hemorrhage | 2019 |
Metabolite Exchange between Mammalian Organs Quantified in Pigs.
Topics: Amino Acids; Animals; Arteries; Blood Glucose; Citric Acid; Fasting; Fatty Acids; Intestinal Mucosa; Kidney; Lactic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Pancreas; Pyruvic Acid; Spleen; Swine; Veins | 2019 |
Kinetic Modeling of Hyperpolarized Carbon-13 Pyruvate Metabolism in the Human Brain.
Topics: Brain; Brain Neoplasms; Carbon Isotopes; Echo-Planar Imaging; Humans; Image Interpretation, Computer-Assisted; Kinetics; Lactic Acid; Pyruvic Acid | 2020 |
Lactate from astrocytes fuels learning-induced mRNA translation in excitatory and inhibitory neurons.
Topics: Animals; Astrocytes; Avoidance Learning; Brain; Citric Acid Cycle; Gangliosides; Glycogenolysis; Hippocampus; Lactic Acid; Male; Memory Consolidation; Memory Disorders; Memory, Episodic; Monocarboxylic Acid Transporters; Neurons; Pyruvic Acid; Rats; Rats, Long-Evans; RNA, Messenger | 2019 |
Effect of infectious bursal disease virus infection on energy metabolism in embryonic chicken livers.
Topics: Adenosine Triphosphate; Animals; Chick Embryo; Chorioallantoic Membrane; Cytosol; Electron Transport Complex I; Energy Metabolism; Glycolysis; Infectious bursal disease virus; L-Lactate Dehydrogenase; Lactic Acid; Liver; Luminescent Measurements; Mitochondria; NAD; Phosphopyruvate Hydratase; Proteins; Pyruvic Acid; Random Allocation; RNA, Viral; Specific Pathogen-Free Organisms; Virulence; Virus Replication | 2019 |
Consequence of insertion trauma - effect on early measurements when using intracerebral devices.
Topics: Animals; Brain; Brain Injuries; Glucose; Glycerol; Lactic Acid; Microdialysis; Prostheses and Implants; Pyruvic Acid; Swine | 2019 |
Purification and partial biochemical characterization of recombinant lactate dehydrogenase 1 (LDH-1) of the white shrimp Litopenaeus vannamei.
Topics: Animals; Cloning, Molecular; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Penaeidae; Protein Multimerization; Pyruvic Acid; Recombinant Proteins; Substrate Specificity | 2019 |
Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia.
Topics: Animals; Benzeneacetamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; HL-60 Cells; Humans; Lactic Acid; Leukemia, Myeloid, Acute; Magnetic Resonance Spectroscopy; Male; Mice; Pyruvic Acid; Thiadiazoles; Treatment Outcome; Xenograft Model Antitumor Assays | 2019 |
Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism.
Topics: Acyl Coenzyme A; Bacterial Proteins; Citrate (si)-Synthase; Citrates; Fatty Acids; Gene Expression Regulation, Bacterial; Glyoxylates; Lactic Acid; Mycobacterium tuberculosis; Pyruvic Acid; Tuberculosis | 2019 |
A Semi-High-Throughput Adaptation of the NADH-Coupled ATPase Assay for Screening Small Molecule Inhibitors.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Enzyme Inhibitors; High-Throughput Screening Assays; Hydrolysis; Lactic Acid; Myosin Type II; NAD; Oxidation-Reduction; Pyruvic Acid | 2019 |
Lactate and pyruvate promote oxidative stress resistance through hormetic ROS signaling.
Topics: Cell Line, Tumor; Humans; Lactic Acid; NF-E2-Related Factor 2; Oxidative Stress; Pyruvic Acid; Reactive Oxygen Species; Signal Transduction; Unfolded Protein Response | 2019 |
Microdialysis Findings in a Patient with New Onset Refractory Non-convulsive Status Epilepticus.
Topics: Anticonvulsants; Electroencephalography; Female; Frontal Lobe; Glucose; Glutamic Acid; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Lactic Acid; Limbic Encephalitis; Microdialysis; Middle Aged; Pyruvic Acid; Status Epilepticus | 2020 |
Lactate topography of the human brain using hyperpolarized
Topics: Adult; Aged; Atlases as Topic; Bicarbonates; Carbon-13 Magnetic Resonance Spectroscopy; Cerebral Cortex; Female; Gray Matter; Humans; Lactic Acid; Male; Middle Aged; Pyruvic Acid; White Matter; Young Adult | 2020 |
Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1.
Topics: Aged; Carbon Isotopes; Humans; Kinetics; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Monocarboxylic Acid Transporters; Neoplasm Grading; Prostatic Neoplasms; PTEN Phosphohydrolase; Pyruvic Acid; Reproducibility of Results; RNA-Seq; Symporters | 2020 |
Dietary Garcinol Attenuates Hepatic Pyruvate and Triglyceride Accumulation by Inhibiting P300/CBP-Associated Factor in Mid-to-Late Pregnant Rats.
Topics: Acetylation; Animals; Antioxidants; Body Weight; Diet; Female; Glycolysis; Lactic Acid; Lipogenesis; Liver; Organ Size; p300-CBP Transcription Factors; Pregnancy; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Terpenes; Triglycerides | 2020 |
Effect of Quorum Sensing on the Ability of
Topics: Acyl-Butyrolactones; Bacterial Proteins; Biofilms; Carbon; Corrosion; Desulfovibrio vulgaris; Energy Metabolism; Gene Expression Regulation; Genes, Bacterial; Lactic Acid; Plankton; Pyruvic Acid; Quorum Sensing; Seawater; Steel; Sulfates; Transcription Factors; Transcriptome | 2019 |
Effect of ILK on small-molecule metabolism of human periodontal ligament fibroblasts with mechanical stretching.
Topics: Amino Acids; Cells, Cultured; Citric Acid; Fibroblasts; Gene Knockdown Techniques; Humans; Lactic Acid; Mechanotransduction, Cellular; Periodontal Ligament; Protein Serine-Threonine Kinases; Pyruvic Acid; RNA Interference; Stress, Mechanical | 2020 |
Intraosseous microdialysis for bone free flap monitoring in head and neck reconstructive surgery: A prospective pilot study.
Topics: Adolescent; Adult; Aged; Bone Neoplasms; Facial Bones; Female; Fibula; Free Tissue Flaps; Glucose; Head and Neck Neoplasms; Humans; Ilium; Lactic Acid; Male; Microdialysis; Middle Aged; Osteoradionecrosis; Pilot Projects; Plastic Surgery Procedures; Prospective Studies; Pyruvic Acid; Young Adult | 2020 |
First hyperpolarized [2-
Topics: Animals; Area Under Curve; Brain; Brain Chemistry; Carbon Isotopes; Energy Metabolism; Feasibility Studies; Glutamic Acid; Healthy Volunteers; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pyruvic Acid; Signal-To-Noise Ratio; Sterilization | 2019 |
Technical-grade chlordane compromises rat Sertoli cells proliferation, viability and metabolic activity.
Topics: Animals; Cell Line; Cell Proliferation; Cell Survival; Chlordan; Glucose; Glucose Transporter Type 3; Insecticides; Lactic Acid; Male; Oxidative Stress; Pyruvic Acid; Rats; Sertoli Cells | 2020 |
Aurora-A mediated phosphorylation of LDHB promotes glycolysis and tumor progression by relieving the substrate-inhibition effect.
Topics: Animals; Aurora Kinase A; Azepines; Cell Line, Tumor; Glycolysis; HEK293 Cells; HeLa Cells; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactic Acid; Male; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasms; Phosphorylation; Pyrimidines; Pyruvic Acid; Serine; Substrate Specificity; Tumor Burden; Xenograft Model Antitumor Assays | 2019 |
A Prospective Observational Feasibility Study of Jugular Bulb Microdialysis in Subarachnoid Hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Cerebrovascular Circulation; Feasibility Studies; Female; Frontal Lobe; Glucose; Glutamic Acid; Glycerol; Humans; Intracranial Aneurysm; Intracranial Pressure; Jugular Veins; Lactic Acid; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Oxygen; Partial Pressure; Prospective Studies; Pyruvic Acid; Subarachnoid Hemorrhage | 2020 |
Differential Effects of Silibinin A on Mitochondrial Function in Neuronal PC12 and HepG2 Liver Cells.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Citrate (si)-Synthase; Hep G2 Cells; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; PC12 Cells; Pyruvic Acid; Rats; Reactive Oxygen Species; Silybin; Silybum marianum | 2019 |
Neuronal lactate levels depend on glia-derived lactate during high brain activity in Drosophila.
Topics: Animals; Astrocytes; Brain; Drosophila; Glucose; Lactic Acid; Monocarboxylic Acid Transporters; Neuroglia; Neurons; Pyruvic Acid | 2020 |
A genetic toolkit for the analysis of metabolic changes in Drosophila provides new insights into metabolic responses to stress and malignant transformation.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Drosophila melanogaster; Energy Metabolism; Fluorescence Resonance Energy Transfer; Glycolysis; Hypoxia; Image Processing, Computer-Assisted; Ketoglutaric Acids; Lactic Acid; Oxygen; Pyruvic Acid | 2019 |
Heterogeneous effect of increasing spinal cord perfusion pressure on sensory evoked potentials recorded from acutely injured human spinal cord.
Topics: Adult; Blood Pressure; Catheterization; Cerebrospinal Fluid Pressure; Electric Stimulation Therapy; Electrophysiology; Evoked Potentials, Somatosensory; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Microdialysis; Middle Aged; Monitoring, Physiologic; Perfusion; Pressure; Pyruvic Acid; Spinal Cord; Spinal Cord Injuries; Tibial Nerve; Tomography, X-Ray Computed; Young Adult | 2020 |
Improving the organization and interactivity of metabolic pathfinding with precomputed pathways.
Topics: Algorithms; Lactic Acid; Metabolic Networks and Pathways; Pyruvic Acid | 2020 |
Noninvasive rapid detection of metabolic adaptation in activated human T lymphocytes by hyperpolarized
Topics: Adaptation, Physiological; Carbon Isotopes; Glycolysis; Humans; Lactic Acid; Leukocytes, Mononuclear; Lymphocyte Activation; Magnetic Resonance Imaging; Pyruvate Dehydrogenase Complex; Pyruvic Acid; T-Lymphocytes | 2020 |
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD
Topics: Bacteria; Bacterial Proteins; Catalase; HeLa Cells; Humans; K562 Cells; Lactic Acid; Mixed Function Oxygenases; NAD; Protein Engineering; Pyruvic Acid; Recombinant Fusion Proteins | 2020 |
Malic Enzyme Facilitates d-Lactate Production through Increased Pyruvate Supply during Anoxic Dark Fermentation in
Topics: Batch Cell Culture Techniques; Lactic Acid; Malate Dehydrogenase; Metabolome; Metabolomics; Oxidation-Reduction; Pyruvic Acid; Synechocystis | 2020 |
Feeding tricarboxylic acid cycle intermediates improves lactate consumption and antibody production in Chinese hamster ovary cell cultures.
Topics: Ammonium Compounds; Animals; Antibody Formation; Bioreactors; Cell Culture Techniques; CHO Cells; Citric Acid Cycle; Cricetinae; Cricetulus; Culture Media; Glucose; Ketoglutaric Acids; Lactic Acid; Pyruvic Acid | 2020 |
Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells.
Topics: Biomarkers; Cell Differentiation; Cells, Cultured; Endothelial Cells; Endothelium, Corneal; Female; Humans; Lactic Acid; Male; Metabolome; Phosphorylation; Proteome; Pyruvic Acid | 2020 |
A metabolite-specific 3D stack-of-spiral bSSFP sequence for improved lactate imaging in hyperpolarized [1-
Topics: Animals; Carbon Isotopes; Humans; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Imaging; Male; Phantoms, Imaging; Pyruvic Acid | 2020 |
An Asymptotic Analysis of the Malonyl-CoA Route to 3-Hydroxypropionic Acid in Genetically Engineered Microbes.
Topics: Genetic Engineering; Industrial Microbiology; Kinetics; Lactic Acid; Malondialdehyde; Malonyl Coenzyme A; Mathematical Concepts; Metabolic Networks and Pathways; Models, Biological; Nonlinear Dynamics; Pyruvic Acid; Synthetic Biology | 2020 |
Changes in mitochondrial function in patients with neuromyelitis optica; correlations with motor and cognitive disabilities.
Topics: Adult; Case-Control Studies; Cognition Disorders; Cytochromes c; Electron Transport Complex I; Electron Transport Complex IV; Female; Humans; Lactic Acid; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Neuromyelitis Optica; Pyruvic Acid; Severity of Illness Index; Sirtuin 1; Sirtuin 3 | 2020 |
Evaluating the potential of hyperpolarised [1-
Topics: Animals; Bicarbonates; Biosensing Techniques; Brain Ischemia; Carbon Isotopes; Computer Systems; Disease Models, Animal; Feasibility Studies; Humans; Immunohistochemistry; Infarction, Middle Cerebral Artery; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Molecular Imaging; Monocarboxylic Acid Transporters; Neuroprotective Agents; Pyruvic Acid; Stroke | 2020 |
Plasma Metabolomic Changes in Mice With Time-restricted Feeding-attenuated Spontaneous Metastasis of Lewis Lung Carcinoma.
Topics: alpha-Tocopherol; Animals; Carcinoma, Lewis Lung; Cholestanol; Cholesterol; Diet, High-Fat; Disease Models, Animal; Docosahexaenoic Acids; Fasting; Humans; Insulin; Isoleucine; Lactic Acid; Leucine; Metabolomics; Mice; Neoplasm Metastasis; Phenylalanine; Pyruvic Acid | 2020 |
Computational Prediction of Chiral Iron Complexes for Asymmetric Transfer Hydrogenation of Pyruvic Acid to Lactic Acid.
Topics: Algorithms; Catalysis; Coordination Complexes; Density Functional Theory; Hydrogenation; Iron; Lactic Acid; Models, Molecular; Molecular Structure; Pyruvic Acid | 2020 |
Enzyme capacity-based genome scale modelling of CHO cells.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Enzymes; Genome Size; Glucose; Kinetics; Lactic Acid; Metabolic Engineering; Metabolic Networks and Pathways; Mitochondria; Models, Genetic; Oxidation-Reduction; Pyruvic Acid | 2020 |
Higher pyruvate levels after Achilles tendon rupture surgery could be used as a prognostic biomarker of an improved patient outcome.
Topics: Achilles Tendon; Adult; Biomarkers; Early Ambulation; Exercise; Female; Humans; Lactic Acid; Male; Middle Aged; Operative Time; Patient Reported Outcome Measures; Pyruvic Acid; Rupture; Time-to-Treatment; Treatment Outcome; Wound Healing | 2021 |
Lactate preconditioning promotes a HIF-1α-mediated metabolic shift from OXPHOS to glycolysis in normal human diploid fibroblasts.
Topics: Cells, Cultured; Diploidy; Fibroblasts; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Pyruvic Acid; Reactive Oxygen Species | 2020 |
Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer.
Topics: Actins; Animals; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Line, Tumor; Epigenomics; Female; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Transgenic; Monocarboxylic Acid Transporters; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; RNA Interference; RNA, Small Interfering; Symporters | 2020 |
Functional Genetic Screening Enables Theranostic Molecular Imaging in Cancer.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Carcinoma, Hepatocellular; CRISPR-Cas Systems; Datasets as Topic; Diethylnitrosamine; Early Detection of Cancer; Humans; L-Lactate Dehydrogenase; Lactic Acid; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Molecular Imaging; Molecular Probes; Precision Medicine; Proof of Concept Study; Pyruvic Acid; Rats | 2020 |
Lactate Production Precedes Inflammatory Cell Recruitment in Arthritic Ankles: an Imaging Study.
Topics: Animals; Ankle; Arthritis, Rheumatoid; Carbon Isotopes; Female; Fluorine; Inflammation; Joints; Lactic Acid; Leukocytes; Magnetic Resonance Spectroscopy; Mice, Inbred BALB C; Mice, Inbred C57BL; Pyruvic Acid | 2020 |
A novel culture medium with reduced nutrient concentrations supports the development and viability of mouse embryos.
Topics: Amino Acids, Essential; Animals; Blastocyst; Culture Media; Dipeptides; Edetic Acid; Embryo Culture Techniques; Embryo Transfer; Female; Fertilization in Vitro; Gene Expression Regulation, Developmental; Glucose; Lactic Acid; Mice; Pyruvic Acid | 2020 |
A Metabolomics Study of Hypoxia Ischemia during Mouse Brain Development Using Hyperpolarized 13C.
Topics: Animals; Brain; Carbon Isotopes; Hypoxia; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Metabolomics; Mice; Pyruvic Acid | 2020 |
Targeting higher levels of lactate in the post-injury period following traumatic brain injury.
Topics: Adult; Biomarkers; Brain Injuries, Traumatic; Female; Humans; Lactic Acid; Male; Middle Aged; Pyruvic Acid | 2020 |
Response of spike-wave discharges in aged APP/PS1 Alzheimer model mice to antiepileptic, metabolic and cholinergic drugs.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Alzheimer Disease; Animals; Anticonvulsants; Atropine; Disease Models, Animal; Donepezil; Drug Administration Schedule; Electroencephalography; Epilepsy; Ethosuximide; GABA Antagonists; Humans; Injections, Intraperitoneal; Lactic Acid; Levetiracetam; Male; Mice; Mice, Transgenic; Nootropic Agents; Organophosphorus Compounds; Parasympatholytics; Plaque, Amyloid; Pyruvic Acid; Video Recording | 2020 |
Pulmonary pyruvate metabolism as an index of inflammation and injury in a rat model of acute respiratory distress syndrome.
Topics: Animals; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Adhesion Molecule-1; Lactic Acid; Lung; Lung Injury; Male; Peroxidase; Pneumonia; Pyruvic Acid; Rats, Sprague-Dawley; Respiratory Distress Syndrome | 2020 |
Integrated metabonomic-proteomic analysis reveals the effect of glucose stress on metabolic adaptation of Lactococcus lactis ssp. lactis CICC23200.
Topics: Adaptation, Physiological; Fermentation; Glucose; Lactic Acid; Lactococcus lactis; Metabolomics; Oxidation-Reduction; Proteomics; Pyruvic Acid; Stress, Physiological | 2020 |
Lactate activation of α-cell K
Topics: Animals; Calcium; Cell Line; Cell Membrane; Glucagon; Glucagon-Secreting Cells; Glucose; Humans; Islets of Langerhans; KATP Channels; Lactic Acid; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pancreas; Primary Cell Culture; Pyruvic Acid | 2020 |
Slice profile effects on quantitative analysis of hyperpolarized pyruvate.
Topics: Area Under Curve; Computer Simulation; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Phantoms, Imaging; Prostatic Neoplasms; Pyruvic Acid; Reproducibility of Results | 2020 |
In Vivo Estimates of Liver Metabolic Flux Assessed by
Topics: Animals; Carbon Isotopes; Citric Acid Cycle; Fumarates; Hydrogen; Isotope Labeling; Lactic Acid; Liver; Male; Metabolic Flux Analysis; Mice, Inbred C57BL; Models, Biological; Oxaloacetic Acid; Propionates; Pyruvic Acid | 2020 |
Dynamic volumetric hyperpolarized
Topics: Animals; Carbon Isotopes; Echo-Planar Imaging; Lactic Acid; Least-Squares Analysis; Magnetic Resonance Imaging; Mice; Phantoms, Imaging; Pyruvic Acid | 2021 |
Noninvasive Epidermal Metabolite Profiling.
Topics: Amino Acids; Epidermis; Humans; Lactic Acid; Lipids; Magnetic Resonance Spectroscopy; Polymers; Proteins; Pyruvic Acid | 2020 |
Hyperpolarized [1-
Topics: Animals; Carbon Isotopes; Cell Line, Tumor; Cell Membrane; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Mice, Nude; Monocarboxylic Acid Transporters; Pyruvic Acid; Symporters | 2020 |
Cerebral nitric oxide and mitochondrial function in patients suffering aneurysmal subarachnoid hemorrhage-a translational approach.
Topics: Animals; Brain Ischemia; Cerebrum; Energy Metabolism; Female; Glutamic Acid; Humans; Lactic Acid; Male; Microdialysis; Middle Aged; Mitochondria; Nitric Oxide; Pyruvic Acid; Rats; Subarachnoid Hemorrhage | 2021 |
Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum.
Topics: Acetates; Adenosine Triphosphate; Energy Metabolism; Lactate Dehydrogenases; Lactic Acid; Metabolic Networks and Pathways; Pyruvic Acid; Treponema pallidum | 2020 |
Effect of Doxorubicin on Myocardial Bicarbonate Production From Pyruvate Dehydrogenase in Women With Breast Cancer.
Topics: Adult; Antibiotics, Antineoplastic; Bicarbonates; Breast Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Cardiotoxicity; Chemotherapy, Adjuvant; Doxorubicin; Early Diagnosis; Feasibility Studies; Female; Heart Diseases; Humans; Lactic Acid; Middle Aged; Mitochondria, Heart; Myocytes, Cardiac; Neoadjuvant Therapy; Predictive Value of Tests; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Time Factors | 2020 |
MRI of [2-
Topics: Animals; Artifacts; Carbon Isotopes; Lactic Acid; Magnetic Resonance Imaging; Phantoms, Imaging; Pyruvic Acid; Rats | 2021 |
Heat acclimation mediated cardioprotection is controlled by mitochondrial metabolic remodeling involving HIF-1α.
Topics: Animals; Cells, Cultured; Hypoxia-Inducible Factor 1, alpha Subunit; L-Lactate Dehydrogenase; Lactic Acid; Male; Mitochondria, Heart; Myocytes, Cardiac; Pyruvic Acid; Rats; Reactive Oxygen Species; Thermotolerance | 2020 |
Phytocompounds curcumin, quercetin, indole-3-carbinol, and resveratrol modulate lactate-pyruvate level along with cytotoxic activity in HeLa cervical cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Movement; Cell Proliferation; Cell Survival; Curcumin; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Indoles; Lactic Acid; Pyruvic Acid; Quercetin; Resveratrol; Tumor Cells, Cultured | 2021 |
Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis.
Topics: Acetyl Coenzyme A; Animals; Citric Acid Cycle; Dichloroacetic Acid; Drosophila melanogaster; Glycolysis; Inflammation; Lactic Acid; Longevity; Oxidative Phosphorylation; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Sepsis | 2020 |
The effect of oral triiodothyronine supplementation on lactate and pyruvate after paediatric cardiac surgery.
Topics: Cardiac Surgical Procedures; Cardiopulmonary Bypass; Child; Dietary Supplements; Humans; Infant; Lactic Acid; Pyruvic Acid; Triiodothyronine | 2021 |
Cloning and characterization of a L-lactate dehydrogenase gene from Ruminococcaceae bacterium CPB6.
Topics: Bacterial Proteins; Cloning, Molecular; Clostridiales; Crystallography, X-Ray; Escherichia coli; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Models, Molecular; Molecular Weight; Plasmids; Protein Structure, Tertiary; Pyruvic Acid; Recombinant Proteins | 2020 |
Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging.
Topics: Animals; Biosensing Techniques; Cells, Cultured; Female; Glycolysis; Green Fluorescent Proteins; HeLa Cells; Humans; Lactic Acid; Mice, Inbred ICR; Molecular Imaging; Myocytes, Cardiac; Neurons; Oligomycins; Pregnancy; Pyruvic Acid; Recombinant Proteins; Serine | 2020 |
Multi-sample measurement of hyperpolarized pyruvate-to-lactate flux in melanoma cells.
Topics: Cell Line, Tumor; Humans; Lactic Acid; Melanoma; Metabolic Flux Analysis; Mutation; Proto-Oncogene Proteins B-raf; Pyruvic Acid; Treatment Outcome | 2021 |
Glutamate-induced modulation in energy metabolism contributes to protection of rat cortical slices against ischemia-induced damage.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Chromatography, High Pressure Liquid; Energy Metabolism; Glutamic Acid; Ketoglutaric Acids; Lactic Acid; Neostriatum; Pyruvic Acid; Rats | 2021 |
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure.
Topics: Animals; Anion Transport Proteins; Cardiomegaly; Heart Failure; Heart-Assist Devices; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Muscle Proteins; Myocytes, Cardiac; Pyruvic Acid; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Ventricular Function, Left | 2021 |
Non-invasive assessment of telomere maintenance mechanisms in brain tumors.
Topics: Alanine; Animals; Biomarkers, Tumor; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Genetic Engineering; Glioma; Lactic Acid; Male; Metabolome; Models, Biological; Neoplasm Grading; Neoplasm Proteins; Proton Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats, Nude; RNA, Messenger; Telomerase; Telomere; Telomere Homeostasis; Xenograft Model Antitumor Assays | 2021 |
Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.
Topics: Alginates; Animals; Bioreactors; Carcinoma, Renal Cell; Cell Line, Tumor; Humans; Kidney Neoplasms; Kinetics; Lactic Acid; Mice; Microspheres; Microtechnology; Models, Animal; Models, Biological; Perfusion; Pyruvic Acid; Signal Processing, Computer-Assisted | 2021 |
Comparison of
Topics: Animals; Carbon Isotopes; Lactic Acid; Lymphoma; Magnetic Resonance Imaging; Mass Spectrometry; Mice; Pyruvic Acid | 2021 |
Biosynthesis of Chlorinated Lactylates in
Topics: Biosynthetic Pathways; Computational Biology; Cyanobacteria; Esters; Halogenation; Lactic Acid; Lauric Acids; Molecular Structure; Multigene Family; Pyruvic Acid | 2021 |
Hyperpolarized
Topics: Aerobiosis; Animals; Aspartic Acid; Brain Neoplasms; Carbon Isotopes; Cell Line, Tumor; Glioblastoma; Glucose; Glycolysis; Humans; Lactic Acid; Magnetic Resonance Imaging; Metabolomics; Mice, SCID; Pyruvic Acid | 2021 |
Lactic Acid Fermentation Is Required for NLRP3 Inflammasome Activation.
Topics: Animals; Cells, Cultured; eIF-2 Kinase; Female; Fermentation; Glycolysis; Lactic Acid; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Peritonitis; Phosphorylation; Pyruvic Acid; Reactive Oxygen Species | 2021 |
Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality.
Topics: Animals; Blood Donors; Blood Preservation; Delta-5 Fatty Acid Desaturase; Erythrocytes; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Humans; Lactic Acid; Metabolomics; Mice; Oxidative Stress; Pyruvic Acid; Stearoyl-CoA Desaturase | 2021 |
Gluconeogenesis is reduced from alanine, lactate and pyruvate, but maintained from glycerol, in liver perfusion of rats with early and late sepsis.
Topics: Alanine; Animals; Gluconeogenesis; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Sepsis | 2021 |
Detection of metabolic change in glioblastoma cells after radiotherapy using hyperpolarized
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line, Tumor; Glioblastoma; Humans; Lactate Dehydrogenase 5; Lactic Acid; Magnetic Resonance Imaging; Metabolomics; Mice, Nude; Pyruvic Acid | 2021 |
Metabolic plasticity enables lifestyle transitions of Porphyromonas gingivalis.
Topics: Amino Acids; Bacterial Adhesion; Bacterial Physiological Phenomena; Biofilms; Carbohydrate Metabolism; Energy Metabolism; Homeostasis; Humans; Lactic Acid; Metabolome; Metabolomics; Oxidation-Reduction; Porphyromonas gingivalis; Pyruvic Acid | 2021 |
Ethyl isopropyl amiloride decreases oxidative phosphorylation and increases mitochondrial fusion in clonal untransformed and cancer cells.
Topics: Amiloride; Cell Line; Cell Line, Tumor; Clone Cells; Epithelial Cells; Epithelial Sodium Channel Blockers; Gene Expression; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Dynamics; Oxidative Phosphorylation; Oxygen Consumption; Phosphofructokinase-1; Pyruvic Acid; Sodium-Hydrogen Exchanger 1 | 2021 |
Activated AMPK promoted the decrease of lactate production in rat Sertoli cells exposed to Zearalenone.
Topics: AMP-Activated Protein Kinases; Animals; Energy Metabolism; Estrogens, Non-Steroidal; Glycolysis; Lactic Acid; Male; Pyruvic Acid; Rats; Sertoli Cells; Zearalenone | 2021 |
Role of insulin/glucagon ratio and cell redox state in the hyperglycaemia induced by exposure to a 60-Hz magnetic field in rats.
Topics: Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Electromagnetic Fields; Energy Metabolism; Fasting; Glucagon; Hyperglycemia; Insulin; Lactic Acid; Lipids; Metabolomics; Oxidation-Reduction; Pyruvic Acid; Rats | 2021 |
Hyperpolarized
Topics: Adult; Bicarbonates; Carbon-13 Magnetic Resonance Spectroscopy; Exercise; Feasibility Studies; Humans; Lactic Acid; Male; Muscle, Skeletal; Prospective Studies; Pyruvic Acid | 2021 |
Denoising of hyperpolarized
Topics: Algorithms; Brain; Computer Simulation; Humans; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid; Signal-To-Noise Ratio | 2021 |
Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney.
Topics: Alanine; Animals; Bicarbonates; Disease Models, Animal; Enzyme Activation; Glucose; Glycolysis; Hematocrit; Humans; Hydrogen-Ion Concentration; Kidney; Lactic Acid; Male; Pyruvate Kinase; Pyruvic Acid; Rats, Wistar | 2021 |
Exometabolome profiling reveals activation of the carnitine buffering pathway in fed-batch cultures of CHO cells co-fed with glucose and lactic acid.
Topics: Animals; Batch Cell Culture Techniques; Carnitine; CHO Cells; Cricetinae; Cricetulus; Glucose; Lactic Acid; Metabolome; Metabolomics; Oxidative Phosphorylation; Pyruvic Acid | 2021 |
Clinical translation of hyperpolarized
Topics: Carbon Isotopes; Humans; Lactic Acid; Magnetic Resonance Imaging; Perfusion Imaging; Pyruvic Acid; Urea | 2022 |
Spontaneous Mutants of Streptococcus sanguinis with Defects in the Glucose-Phosphotransferase System Show Enhanced Post-Exponential-Phase Fitness.
Topics: Bacterial Proteins; DNA, Bacterial; Gene Deletion; Gene Expression Regulation, Bacterial; Glucose; Hydrogen Peroxide; Lactic Acid; Phosphotransferases; Pyruvic Acid; Streptococcus sanguis | 2021 |
Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia.
Topics: Adaptation, Physiological; Amino Acids; AMP-Activated Protein Kinase Kinases; Animals; Female; Glycolysis; Hypoxia; Lactic Acid; Maternal-Fetal Exchange; Oxygen; Placental Circulation; Pregnancy; Pyruvic Acid; Sheep | 2021 |
Metabolite-Specific Echo-Planar Imaging of Hyperpolarized [1-
Topics: Animals; Echo-Planar Imaging; Lactic Acid; Phantoms, Imaging; Pyruvic Acid; Radio Waves; Rats | 2021 |
Lactate and Pyruvate Activate Autophagy and Mitophagy that Protect Cells in Toxic Model of Parkinson's Disease.
Topics: Animals; Astrocytes; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Mitophagy; NAD; Neurons; Parkinson Disease; Pyruvic Acid; Rats | 2022 |
Lactate and pyruvate levels correlation with lactate dehydrogenase gene expression and glucose consumption in Tamoxifen-resistant MCF-7 cells using capillary electrophoresis with contactless conductivity detection (CE-C
Topics: Breast Neoplasms; Electric Conductivity; Electrophoresis, Capillary; Female; Gene Expression; Glucose; Humans; L-Lactate Dehydrogenase; Lactic Acid; MCF-7 Cells; Pyruvic Acid; Tamoxifen | 2022 |
The blood lactate/pyruvate equilibrium affair.
Topics: Animals; Carbon Radioisotopes; Dogs; Exercise; Femoral Artery; Femoral Vein; Humans; Immunohistochemistry; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle, Skeletal; Pyruvic Acid; Radioactive Tracers; Rest; Signal Transduction | 2022 |
Early detection of anastomotic leakage after pancreatoduodenectomy with microdialysis catheters: an observational Study.
Topics: Aged; Anastomotic Leak; Catheters; Glucose; Glycerol; Humans; Inflammation; Lactic Acid; Microdialysis; Pancreaticoduodenectomy; Postoperative Complications; Pyruvic Acid | 2022 |
Characterising the dynamics of cerebral metabolic dysfunction following traumatic brain injury: A microdialysis study in 619 patients.
Topics: Adult; Arterial Pressure; Brain; Brain Injuries, Traumatic; Female; Glasgow Coma Scale; Glucose; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen Saturation; Pyruvic Acid; Young Adult | 2021 |
A Man With Left Ventricular Hypertrophy.
Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Glucose Intolerance; Hearing Loss, Sensorineural; Humans; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Hypothyroidism; Lactic Acid; Magnetic Resonance Imaging; Male; Mitochondria, Heart; Mitochondrial Diseases; Muscle Weakness; Myocardium; Pyruvic Acid; Ventricular Dysfunction, Left | 2022 |
Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions.
Topics: Cell Line, Tumor; Cell Proliferation; Culture Media; Glucose; Glutamine; HeLa Cells; Humans; Lactic Acid; Metabolomics; Metformin; NAD; Oxygen; Pyruvic Acid; Tumor Hypoxia | 2022 |
Quantitative analysis of the interaction of ethanol metabolism with gluconeogenesis and fatty acid oxidation in the perfused liver of fasted rats.
Topics: Animals; Ethanol; Fatty Acids; Gluconeogenesis; Lactic Acid; Lipid Metabolism; Liver; NAD; Oxidation-Reduction; Pyruvic Acid; Rats | 2022 |
A reproducible dynamic phantom for sequence testing in hyperpolarised
Topics: Carbon Isotopes; Humans; Lactate Dehydrogenases; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Pyruvic Acid; Reproducibility of Results | 2022 |
Alteration in glucose metabolism in the brain associated with tamoxifen treatment: Study in postmenopausal animal model.
Topics: Animals; Disease Models, Animal; Female; Glucose; Hippocampus; Humans; Hyperglycemia; Lactic Acid; Postmenopause; Pyruvic Acid; Quercetin; Rats; Tamoxifen | 2022 |
Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme.
Topics: Acidosis, Lactic; Animals; Citrates; Hydrogen-Ion Concentration; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Muscle, Skeletal; Pyruvic Acid; Rabbits | 2022 |
Hyperpolarized
Topics: Animals; Boidae; Carbon Isotopes; Digestion; Lactic Acid; Magnetic Resonance Imaging; Mammals; Pyruvic Acid; Swine | 2022 |
Lactate saturation limits bicarbonate detection in hyperpolarized
Topics: Animals; Bicarbonates; Brain; Carbon Isotopes; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid; Rats | 2022 |
Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 2; Glucagon; Gluconeogenesis; Glucose; Lactic Acid; Liver; Mice; Pyruvic Acid | 2022 |
Deuterium Metabolic Imaging Reports on TERT Expression and Early Response to Therapy in Cancer.
Topics: Animals; Deuterium; Glioblastoma; Lactic Acid; Mice; NAD; Pyruvic Acid; Telomerase | 2022 |
Characterization of carbohydrate metabolism in in vivo- and in vitro-grown and matured mouse antral follicles†.
Topics: Animals; Antioxidants; Cumulus Cells; Female; Glucose; Hexosamines; Humans; Lactic Acid; Mice; NADP; Oocytes; Pentose Phosphate Pathway; Pyruvic Acid; Tricarboxylic Acids | 2022 |
Imaging Neurodegenerative Metabolism in Amyotrophic Lateral Sclerosis with Hyperpolarized [1-
Topics: Amyotrophic Lateral Sclerosis; Bicarbonates; Humans; Lactic Acid; Magnetic Resonance Imaging; Neurodegenerative Diseases; Pyruvic Acid | 2022 |
Kinetic analysis of multi-resolution hyperpolarized
Topics: Brain; Carbon Isotopes; Humans; Kinetics; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid | 2022 |
Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8
Topics: CD8-Positive T-Lymphocytes; Humans; Immunity; Lactic Acid; Neoplasms; Pyruvate Carboxylase; Pyruvic Acid; Succinic Acid; Tumor Microenvironment | 2022 |
Imaging Glioblastoma Metabolism by Using Hyperpolarized [1-
Topics: Bicarbonates; Glioblastoma; Humans; Lactate Dehydrogenase 5; Lactic Acid; Male; Middle Aged; Prospective Studies; Pyruvic Acid | 2022 |
Inhibition of LPAR6 overcomes sorafenib resistance by switching glycolysis into oxidative phosphorylation in hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Glycolysis; Humans; Lactic Acid; Liver Neoplasms; Oxidative Phosphorylation; Pyruvic Acid; Receptors, Lysophosphatidic Acid; Sorafenib | 2022 |
Aspirin blocks AMPK/SIRT3-mediated glycolysis to inhibit NSCLC cell proliferation.
Topics: AMP-Activated Protein Kinases; Aspirin; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Glycolysis; Hexokinase; Humans; Lactic Acid; Lung Neoplasms; Peptidyl-Prolyl Isomerase F; Proliferating Cell Nuclear Antigen; Pyruvic Acid; Reactive Oxygen Species; RNA, Small Interfering; Sirtuin 3 | 2022 |
Assessment of higher-order singular value decomposition denoising methods on dynamic hyperpolarized [1-
Topics: Bicarbonates; Glioma; Humans; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid | 2022 |
Second-Order Kinetic Rate Coefficients for the Aqueous-Phase Sulfate Radical (SO
Topics: Aerosols; Lactic Acid; Nitrates; Organic Chemicals; Oxidants; Oxidation-Reduction; Pyruvic Acid; Sulfates; Sulfur; Sulfur Dioxide; Water | 2022 |
Compounds from human odor induce attraction and landing in female yellow fever mosquitoes (Aedes aegypti).
Topics: Aedes; Animals; Female; Humans; Ketoglutaric Acids; Lactic Acid; Mosquito Vectors; Odorants; Pyruvic Acid; Yellow Fever; Zika Virus; Zika Virus Infection | 2022 |
PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells.
Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Glycolysis; Humans; Lactic Acid; Ovarian Neoplasms; Paclitaxel; Phosphoglycerate Mutase; Pyruvic Acid; RNA, Small Interfering | 2022 |
Cellular Lactate Spectroscopy Using 1.5 Tesla Clinical Apparatus.
Topics: Glucose; Glycogen; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Neoplasms; Protons; Pyruvic Acid | 2022 |
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke.
Topics: Biomarkers; Blood Glucose; Brain Ischemia; C-Reactive Protein; Homocysteine; Humans; Hypertension; Ischemic Stroke; Lactic Acid; Methylamines; Oxides; Pyruvic Acid; Stroke | 2022 |
Oxidation of hyperpolarized [1-
Topics: Animals; Bicarbonates; Caprylates; Carbon Isotopes; Humans; Kidney; Lactic Acid; Pyruvic Acid; Rats | 2023 |
Clinical, Biochemical, and Molecular Characterization of Two Families with Novel Mutations in the
Topics: Codon, Nonsense; Dermatitis; Female; Glycogen Storage Disease; Humans; Isoenzymes; Lactate Dehydrogenase 5; Lactic Acid; Mutation; Pyruvic Acid | 2022 |
Glucose assimilation rate determines the partition of flux at pyruvate between lactic acid and ethanol in Saccharomyces cerevisiae.
Topics: Ethanol; Fermentation; Glucose; Lactic Acid; Oxidoreductases; Pyruvic Acid; Saccharomyces cerevisiae; Xylose | 2023 |
Pyruvate and lactate based hydrogel film inhibits UV radiation-induced skin inflammation and oxidative stress.
Topics: Dihydroxyphenylalanine; Humans; Hydrogels; Inflammation; Lactic Acid; Oxidative Stress; Pyruvic Acid; Skin; Skin Diseases; Ultraviolet Rays | 2023 |
Hyperpolarized
Topics: Carbon Isotopes; Glucose; Heterografts; Humans; Immune Checkpoint Inhibitors; Lactic Acid; Melanoma; Pyruvic Acid | 2023 |
Pearls & Oy-sters: Paroxysmal Exercise-Induced Dyskinesias Due to Pyruvate Dehydrogenase Deficiency.
Topics: Child, Preschool; Chorea; Dystonia; Humans; Lactic Acid; Male; Pyruvate Dehydrogenase Complex Deficiency Disease; Pyruvic Acid | 2023 |
SMOKING JEOPARDIZED MITOCHONDRIAL FUNCTION VITIATING LIPID PROFILE.
Topics: Humans; Lactic Acid; Lipids; Mitochondria; Pyruvic Acid; Tobacco Smoking | 2023 |
Monitoring live mitochondrial metabolism in real-time using NMR spectroscopy.
Topics: Animals; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mitochondria; Pyruvic Acid | 2023 |
Cottonseed hydrolysate supplementation alters metabolic and proteomics responses in Chinese hamster ovary cell cultures.
Topics: Amino Acids; Animals; Batch Cell Culture Techniques; CHO Cells; Cottonseed Oil; Cricetinae; Cricetulus; Dietary Supplements; Lactic Acid; Polyamines; Proteomics; Pyruvic Acid | 2023 |
Electrochemical characterization of a dual cytochrome-containing lactate dehydrogenase.
Topics: Cytochromes c; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Oxidation-Reduction; Oxygen; Pyruvic Acid; Saccharomyces cerevisiae | 2023 |
Spectrally selective bSSFP using off-resonant RF excitations permits high spatiotemporal resolution 3D metabolic imaging of hyperpolarized [1-
Topics: Animals; Carbon Isotopes; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Imaging; Mice; Phantoms, Imaging; Pyruvic Acid | 2023 |
A Simulation of the Effects of Diffusion on Hyperpolarized [1-
Topics: Carbon Isotopes; Computer Simulation; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid | 2023 |
Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized
Topics: Animals; Echo-Planar Imaging; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Mice; Prostatic Neoplasms; Pyruvic Acid | 2023 |
Impact of acute stress on murine metabolomics and metabolic flux.
Topics: Animals; Carbon Isotopes; Citric Acid Cycle; Glucose; Isotope Labeling; Lactic Acid; Mammals; Metabolomics; Mice; Pyruvic Acid | 2023 |
Age-associated change in pyruvate metabolism investigated with hyperpolarized
Topics: Bicarbonates; Brain; Carbon Isotopes; Humans; Lactic Acid; Magnetic Resonance Imaging; Pyruvic Acid | 2023 |
Low CO
Topics: Animals; Carbon Dioxide; CHO Cells; Cricetinae; Cricetulus; Lactic Acid; Partial Pressure; Pyruvic Acid | 2023 |
Circular cell culture for sustainable food production using recombinant lactate-assimilating cyanobacteria that supplies pyruvate and amino acids.
Topics: Amino Acids; Animals; Cell Culture Techniques; Lactic Acid; Pyruvic Acid; Synechococcus | 2023 |
Energy metabolic mechanisms for high altitude sickness: Downregulation of glycolysis and upregulation of the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation.
Topics: Altitude; Altitude Sickness; Amino Acids; Animals; Citric Acid Cycle; Down-Regulation; Fatty Acids; Glucokinase; Glycolysis; Humans; Hypoxia; Lactic Acid; Mice; Pyruvic Acid; Up-Regulation | 2023 |
Pyruvate-conjugation of PEGylated liposomes for targeted drug delivery to retinal photoreceptors.
Topics: Animals; Cysteine; Drug Delivery Systems; Humans; Lactic Acid; Liposomes; Mice; Monocarboxylic Acid Transporters; Photoreceptor Cells, Vertebrate; Polyethylene Glycols; Pyruvic Acid | 2023 |
Greater reliance on glycolysis is associated with lower mitochondrial substrate oxidation and insulin sensitivity in infant myogenic MSCs.
Topics: Carbon Dioxide; Glucose; Glycolysis; Humans; Insulin; Insulin Resistance; Lactic Acid; Mesenchymal Stem Cells; Muscle, Skeletal; Obesity; Pyruvic Acid | 2023 |
Early brain metabolic disturbances associated with delayed cerebral ischemia in patients with severe subarachnoid hemorrhage.
Topics: Brain; Brain Ischemia; Cerebral Infarction; Glucose; Glutamic Acid; Humans; Lactic Acid; Pyruvic Acid; Retrospective Studies; Subarachnoid Hemorrhage | 2023 |
Hyperpolarized [2-
Topics: Brain; Glutamic Acid; Humans; Lactic Acid; Magnetic Resonance Imaging; Molecular Imaging; Pyruvic Acid | 2023 |
Identifying possible biomarkers of lower urinary tract symptoms using metabolomics and partial least square regression.
Topics: Biomarkers; Humans; Lactic Acid; Least-Squares Analysis; Lower Urinary Tract Symptoms; Male; Metabolomics; Methionine; Pyruvic Acid; Racemethionine | 2023 |
Altered markers of mitochondrial function in adults with autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Carnitine; Fatty Acids; Female; Humans; Lactic Acid; Male; Mitochondria; Pyruvic Acid | 2023 |
Hyperpolarized [1-
Topics: Agmatine; Animals; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lactic Acid; Mice; Mice, Inbred ICR; NAD; Pyruvic Acid | 2023 |
Changes in metabolite content in the kidneys and skeletal muscles of rats fed magnesium-restricted diets.
Topics: Animals; Kidney; Lactic Acid; Magnesium; Muscle, Skeletal; Pyruvic Acid; Rats | 2023 |
Real-time resolution studies of the regulation of pyruvate-dependent lactate metabolism by hexokinases in single cells.
Topics: Aspartic Acid; HEK293 Cells; Hexokinase; Humans; Lactic Acid; Malates; Pyruvic Acid | 2023 |
LC-MS/MS method for quantitative profiling of ketone bodies, α-keto acids, lactate, pyruvate and their stable isotopically labelled tracers in human plasma: An analytical panel for clinical metabolic kinetics and interactions.
Topics: Acetoacetates; Chromatography, Liquid; Humans; Keto Acids; Ketone Bodies; Lactic Acid; Pyruvic Acid; Tandem Mass Spectrometry | 2023 |
Near-Physiological Concentrations of Extracellular Pyruvate Stimulated Glucose Utilization along with Triglyceride Accumulation and Mitochondrial Activity in HepG2 Cells.
Topics: Glucose; Hep G2 Cells; Humans; Lactic Acid; Mitochondria; Pyruvic Acid | 2023 |
Visualizing Monocarboxylates and Other Relevant Metabolites in the Ex Vivo Drosophila Larval Brain Using Genetically Encoded Sensors.
Topics: Animals; Brain; Drosophila; Glucose; Lactic Acid; Pyruvic Acid | 2023 |
High-sensitivity deuterium metabolic MRI differentiates acute pancreatitis from pancreatic cancers in murine models.
Topics: Acute Disease; Animals; Deuterium; Disease Models, Animal; Humans; Lactic Acid; Magnetic Resonance Imaging; Mice; Pancreatic Neoplasms; Pancreatitis; Pyruvic Acid | 2023 |