lactic acid has been researched along with pyruvaldehyde in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (9.38) | 18.7374 |
| 1990's | 12 (18.75) | 18.2507 |
| 2000's | 11 (17.19) | 29.6817 |
| 2010's | 25 (39.06) | 24.3611 |
| 2020's | 10 (15.63) | 2.80 |
| Authors | Studies |
|---|---|
| Kawakami, Y; Kawase, M; Kondoh, Y; Ohmori, S | 1 |
| Kawase, M; Kondoh, Y; Ohmori, S | 1 |
| Herzog, SL; Kaminsky, M; Shires, TK; Tresnak, J; Truc-Pham, B | 1 |
| Banerjee, AB; Ghoshal, K; Ray, S | 1 |
| Hooper, NI; Thornalley, PJ; Tisdale, MJ | 1 |
| Thornalley, PJ | 1 |
| Creighton, DJ; Guha, MK; Migliorini, M; Pourmotabbed, T | 1 |
| Chandramouli, V; Kosugi, K; Kumaran, K; Landau, BR; Schumann, WC | 1 |
| Stern, A; Thornalley, PJ | 1 |
| Banerjee, AB; Misra, K; Ray, M; Ray, S | 1 |
| Buzzi, E; Leoncini, G | 1 |
| Hirata, M; Kawase, M; Kondoh, Y; Ohmori, S | 1 |
| Benn, J; McLellan, AC; Sonksen, PH; Thornalley, PJ | 1 |
| Phillips, SA; Thornalley, PJ | 1 |
| Halder, J; Ray, M; Ray, S | 1 |
| Lieber, MM | 1 |
| Beisswenger, P; Brownlee, M; Giardino, I; Onorato, J; Shinohara, M; Thornalley, PJ; Thorpe, SR | 1 |
| Beisswenger, PJ; Howell, SK; Lal, S; Szwergold, BS; Touchette, AD | 1 |
| Jahan, I; Ng, R; Thornalley, PJ | 1 |
| Cordeiro, CA; Martins, AM; Ponces Freire, AM | 1 |
| Akagi, S; Ohmori, S | 1 |
| Akagi, S; Fujisawa, T; Kawase, M; Ohmori, S; Yamamoto, M | 1 |
| Atlante, A; de Bari, L; Passarella, S; Paventi, G; Pizzuto, R; Valenti, D | 1 |
| Grochowski, LL; White, RH; Xu, H | 1 |
| Burnell, J; de Arriba, SG; Loske, C; Münch, G; Stuchbury, G; Yarin, J | 1 |
| Grabar, TB; Ingram, LO; Shanmugam, KT; Yomano, LP; Zhou, S | 1 |
| Kim, I; Kim, J; Lee, C; Min, B; Park, C | 1 |
| Kawase, M; Kitamura, Y; Ohmori, S | 1 |
| Janáky, T; Karg, E; Papp, F; Tassi, N; Túri, S; Wittmann, G | 1 |
| Battu, CE; de Assis, AM; Farina, M; Gonçalves, CA; Hansen, F; Hoefel, AL; Longoni, A; Perry, ML; Rieger, DK; Schmidt, B; Sordi, F; Souza, DO | 1 |
| Dmitriev, LF; Dmitriev, VA; Krylin, VA; Titov, VN | 1 |
| Adeli, K; Krahn, J; Lu, J; Meng, QH; Randell, E; Zello, GA | 1 |
| Chen, CM; Chen, HY; Huang, TC; Lee, JA; Liao, TH; Lin, MH | 1 |
| Pallotta, ML | 1 |
| Bobermin, LD; de Souza, DF; Fontoura, JB; Gonçalves, CA; Hansen, F; Hoefel, AL; Leite, MC; Perry, ML; Silveira, Sda L; Tramontina, AC | 1 |
| Hess, C; Madea, B; Musshoff, F; Quester, W; Stratmann, B; Tschoepe, D | 1 |
| Blankschien, MD; Clomburg, JM; Gonzalez, R; Mazumdar, S | 1 |
| Bench, G; Knaack, JL; Kulp, KS; Navid, A; Stewart, BJ | 1 |
| Hsu, WH; Hsu, YW; Lee, BH; Pan, TM | 1 |
| Kuchel, PW; Naumann, C; Pagès, G | 1 |
| Bruno, RS; Lee, J; Mah, E; Manautou, JE; Masterjohn, C; Park, Y; Pei, R | 1 |
| Chandrangsu, P; Dusi, R; Hamilton, CJ; Helmann, JD | 1 |
| Eckert, GJ; Fleming, T; Kiefer, AS; Nawroth, PP; Poindexter, BB; Yoder, MC | 1 |
| Choi, D; Ha, S; Kim, EH; Kim, J; Kwon, K; Lee, HY; Park, C; Ryu, KS | 1 |
| Hu, K; Jiang, B; Le, L; Pan, H; Xiao, P; Xu, L | 1 |
| Asiago, JM; Aslam, K; Drendel, HM; Goode, KM; Hazbun, TR; Paul, LN; Rochet, JC; Tsai, CJ | 1 |
| Dembinska-Kiec, A; Goralska, J; Gruca, A; Kiec-Wilk, B; Malczewska-Malec, M; Masania, J; Rabbani, N; Razny, U; Stancel-Mozwillo, J; Thornalley, PJ; Zdzienicka, A | 1 |
| Braun, HP; Fuchs, P; García, L; Gonzalez, DH; Maurino, VG; Schertl, P; Schmitz, J; Schwarzländer, M; Wagner, S; Welchen, E; Wienstroer, J | 1 |
| Ito, Y; Kimura, M; Kojima, W; Koyano, F; Matsuda, N; Mishima, M; Mizushima, T; Queliconi, BB; Takagi, K; Tanaka, K; Yamano, K | 1 |
| Bains, Y; Caccavello, R; Garay-Sevilla, ME; Gugliucci, A; Luevano-Contreras, C; Rodríguez-Mortera, R; Solorio-Meza, S | 1 |
| Beitz, E; Bertl, A; Figarella, K; Lang, F; Marsiccobetre, S; Rodríguez-Acosta, A; Segnini, A; Uzcátegui, NL | 1 |
| Bisgaard Olesen, S; Galligan, JJ; Johannsen, M; Jørgensen, KA; Nielsen, CB; Palmfeldt, J; Schou Oxvig, AM; Sibbersen, C | 1 |
| Bains, Y; Caccavello, R; Erkin-Cakmak, A; Gugliucci, A; Lustig, RH; Mulligan, K; Noworolski, SM; Schwarz, JM | 1 |
| Armeni, T; Atlante, A; de Bari, L; Kalapos, MP | 1 |
| Kim, SY; Lee, JH; Subedi, L | 1 |
| Chen, HH; Chen, SM; Cheng, HW; Cheng, YF; Imai, K; Lin, CE | 1 |
| Caccavello, R; Gugliucci, A | 1 |
| Chang, HT; Chen, CM; Chen, SM; Chen, TH; Imai, K; Lee, JA; Lin, CY; Lin, TY; Tsai, PY | 1 |
| Chen, BL; Chen, SM; Hua, SC; Lee, JA; Lee, TH; Lin, CE; Lin, CY; Lin, PY; Tsai, PY | 1 |
| Chen, CM; Chen, HS; Chen, SM; Huang, YS; Lee, JA; Lin, CE; Lin, PY; Lin, TY; Yang, WC | 1 |
| Bergmans, DCJJ; Driessen, RGH; Gerretsen, J; Kiers, D; Kox, M; Pickkers, P; Schalkwijk, CG; Scheijen, JLJM; van Bussel, BCT; van de Poll, MCG; van der Horst, ICC | 1 |
| Bennewitz, K; Erben, V; Fleming, T; Hausser, I; Kroll, J; Lodd, E; Middel, CS; Morgenstern, J; Nawroth, PP; Ott, H; Poschet, G; Poth, T; Sticht, C; Szendroedi, J; Tabler, CT | 1 |
| Cha, S; Choi, J; Hwang, E; Jung, HM; Lee, D; Lee, JH; Park, C; Ryu, KS; Tak, S | 1 |
| Coukos, JS; Lee, CW; Moellering, RE; Pillai, KS; Shah, H | 1 |
2 review(s) available for lactic acid and pyruvaldehyde
| Article | Year |
|---|---|
Dicarbonyl stress in clinical obesity.
Topics: Animals; Diabetes Mellitus, Type 2; Humans; Lactic Acid; Lactoylglutathione Lyase; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Pyruvaldehyde; Stress, Physiological | 2016 |
Synthesis and metabolism of methylglyoxal, S-D-lactoylglutathione and D-lactate in cancer and Alzheimer's disease. Exploring the crossroad of eternal youth and premature aging.
Topics: Aging, Premature; Alzheimer Disease; Animals; Energy Metabolism; Glutathione; Glycolysis; Humans; Lactic Acid; Lactoylglutathione Lyase; Neoplasms; Pyruvaldehyde; Thiolester Hydrolases | 2019 |
1 trial(s) available for lactic acid and pyruvaldehyde
| Article | Year |
|---|---|
Metformin reduces systemic methylglyoxal levels in type 2 diabetes.
Topics: Adult; Aged; Deoxyglucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Middle Aged; Osmolar Concentration; Pyruvaldehyde; Sulfonylurea Compounds; Treatment Outcome | 1999 |
61 other study(ies) available for lactic acid and pyruvaldehyde
| Article | Year |
|---|---|
Concentrations of D-lactate and its related metabolic intermediates in liver, blood, and muscle of diabetic and starved rats.
Topics: Animals; Blood Chemical Analysis; Blood Glucose; Diabetes Mellitus, Experimental; Enzymes; Food Deprivation; Lactates; Lactic Acid; Liver; Male; Muscles; Pyruvaldehyde; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Streptozocin | 1992 |
D-lactate concentrations in blood, urine and sweat before and after exercise.
Topics: Adult; Energy Metabolism; Exercise Therapy; Humans; Lactates; Lactic Acid; Male; Physical Exertion; Pyruvaldehyde; Pyruvates; Pyruvic Acid; Running; Sodium; Sweat | 1992 |
DNA modification in vivo by derivatives of glucose: enhancement by glutathione depletion.
Topics: Cell Line; Centrifugation, Isopycnic; DNA; Glucose; Glutathione; Glycogen; Lactates; Lactic Acid; Lactoylglutathione Lyase; Methionine Sulfoximine; Pyruvaldehyde | 1990 |
Methylglyoxal-catabolizing enzymes of Leishmania donovani promastigotes.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Aldehydes; Animals; Dihydroxyacetone Phosphate; Lactates; Lactic Acid; Leishmania donovani; Oxidation-Reduction; Pyruvaldehyde; Toluene | 1989 |
Modification of the glyoxalase system in human HL60 promyelocytic leukaemia cells during differentiation to neutrophils in vitro.
Topics: Cell Differentiation; Cell Line; Formamides; Glutathione; Humans; Lactates; Lactic Acid; Lactoylglutathione Lyase; Leukemia, Myeloid, Acute; Lyases; Neutrophils; Pyruvaldehyde; Substrate Specificity; Thiolester Hydrolases | 1988 |
Modification of the glyoxalase system in human red blood cells by glucose in vitro.
Topics: Erythrocytes; Glucose; Glutathione; Humans; Hyperglycemia; In Vitro Techniques; Lactates; Lactic Acid; Lactoylglutathione Lyase; Lyases; Models, Biological; Pyruvaldehyde; Trisaccharides | 1988 |
Optimization of efficiency in the glyoxalase pathway.
Topics: Animals; Erythrocytes; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lactates; Lactic Acid; Lactoylglutathione Lyase; Lyases; Mercaptoethanol; Pyruvaldehyde; Rats; Stereoisomerism; Substrate Specificity; Swine; Thermodynamics; Thioglycolates; Thiolester Hydrolases | 1988 |
Determinants in the pathways followed by the carbons of acetone in their conversion to glucose.
Topics: Acetates; Acetic Acid; Acetone; Aldehyde Dehydrogenase; Animals; Carbon; Glucose; Lactates; Lactic Acid; Models, Biological; Pyruvaldehyde; Rats; Rats, Inbred Strains | 1986 |
Red blood cell oxidative metabolism induced by hydroxypyruvaldehyde.
Topics: Adult; Blood Glucose; Erythrocytes; Free Radicals; Glutathione; Hemoglobins; Humans; In Vitro Techniques; Lactates; Lactic Acid; Malonates; Malondialdehyde; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Pentose Phosphate Pathway; Pyruvaldehyde; Pyruvates; Pyruvic Acid | 1985 |
Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione.
Topics: Aldehyde Oxidoreductases; Dithiothreitol; Escherichia coli; Glutathione; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Lactates; Lactic Acid; Molecular Weight; Oxidation-Reduction; Phenylglyoxal; Pyruvaldehyde; Substrate Specificity; Sulfhydryl Compounds | 1995 |
Thrombin induces S-D-lactoylglutathione accumulation by enhancing platelet glycolytic pathway.
Topics: Alkylation; Blood Platelets; Glutathione; Glycolysis; Humans; Iodoacetamide; Lactates; Lactic Acid; Pyruvaldehyde; Thrombin | 1994 |
Carbon sources for D-lactate formation in rat liver.
Topics: Acetoacetates; Acetone; Animals; Diabetes Mellitus, Experimental; Glucose; Glycerol; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Pyruvaldehyde; Rats; Rats, Wistar; Starvation; Threonine | 1994 |
Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications.
Topics: Adult; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Erythrocytes; Female; Glutathione; Glycated Hemoglobin; Growth Inhibitors; Humans; Lactates; Lactic Acid; Lactoylglutathione Lyase; Male; Middle Aged; Pyruvaldehyde; Time Factors | 1994 |
Formation of methylglyoxal and D-lactate in human red blood cells in vitro.
Topics: Erythrocytes; Humans; In Vitro Techniques; Lactates; Lactic Acid; Pyruvaldehyde | 1993 |
Inhibition of glycolysis and mitochondrial respiration of Ehrlich ascites carcinoma cells by methylglyoxal.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Chickens; Cytosol; Enzyme Activation; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Hexokinase; Lactates; Lactic Acid; Mice; Mitochondria; Muscles; Oxygen Consumption; Pyruvaldehyde; Tumor Cells, Cultured | 1993 |
Force, development, and neoplasia: development from another perspective as illustrated through a study of in vitro plant development from neoplasm.
Topics: Adaptation, Physiological; Animals; Ascorbic Acid; Biological Evolution; Culture Media; Culture Techniques; Embryonic and Fetal Development; Fabaceae; Humans; Lactic Acid; Mammals; Mice; Mutagenesis; Neoplasms; Nicotiana; Plant Development; Plant Tumors; Plants; Plants, Medicinal; Plants, Toxic; Pyruvaldehyde; Temperature; Time Factors | 1996 |
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
Topics: Acetone; Aldehydes; Animals; Cattle; Endocytosis; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Glycation End Products, Advanced; Glyoxal; Hyperglycemia; Ketones; Lactic Acid; Lactoylglutathione Lyase; Lysine; Pyruvaldehyde; Transfection; Tumor Cells, Cultured | 1998 |
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Pentosephosphates; Pyruvaldehyde; Pyruvic Acid; Sugar Phosphates; Thiamine; Transketolase; Trioses | 2001 |
In situ analysis of methylglyoxal metabolism in Saccharomyces cerevisiae.
Topics: Aerobiosis; Cell Division; Ethanol; Glucose; Glycolysis; L-Lactate Dehydrogenase; Lactic Acid; Lactoylglutathione Lyase; Pyruvaldehyde; Saccharomyces cerevisiae; Thiolester Hydrolases | 2001 |
Threonine is the best substrate for D-lactate formation in octopus tentacle.
Topics: Animals; Extremities; Glutathione; Glycine; Lactic Acid; Liver; Male; Octopodiformes; Pyruvaldehyde; Rats; Rats, Wistar; Threonine; Time Factors | 2004 |
D-lactate metabolism in starved Octopus ocellatus.
Topics: Animals; Energy Metabolism; Enzymes; Extremities; Food Deprivation; Japan; Lactic Acid; Octopodiformes; Pyruvaldehyde; Pyruvic Acid; Spectrophotometry | 2005 |
Transport and metabolism of D-lactate in Jerusalem artichoke mitochondria.
Topics: Biological Transport; Cytosol; Helianthus; Lactate Dehydrogenases; Lactic Acid; Mitochondria; Oxygen Consumption; Plant Roots; Pyruvaldehyde; Stereoisomerism; Symporters; Thiolester Hydrolases | 2005 |
Identification of lactaldehyde dehydrogenase in Methanocaldococcus jannaschii and its involvement in production of lactate for F420 biosynthesis.
Topics: Aldehyde Oxidoreductases; Aldehydes; Amino Acid Sequence; Archaeal Proteins; Cloning, Molecular; Escherichia coli; Fructose-Bisphosphate Aldolase; Hexosephosphates; Lactic Acid; Methanococcales; Molecular Sequence Data; Pyruvaldehyde; Recombinant Proteins; Riboflavin; Sequence Homology, Amino Acid | 2006 |
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers.
Topics: Adenosine Triphosphate; Analysis of Variance; Cell Line, Tumor; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Flow Cytometry; Glucose; Guanidines; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; Neurons; Piperazines; Pyruvaldehyde; Reactive Oxygen Species; Thiophenes | 2007 |
Methylglyoxal bypass identified as source of chiral contamination in l(+) and d(-)-lactate fermentations by recombinant Escherichia coli.
Topics: Biotechnology; Carbon-Oxygen Lyases; Escherichia coli; Fermentation; Gene Deletion; Glycolysis; Industrial Microbiology; Lactic Acid; Pyruvaldehyde; Recombinant Proteins; Stereoisomerism | 2006 |
Screening of genes related to methylglyoxal susceptibility.
Topics: Acetone; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flagella; Genes, Bacterial; Genome, Bacterial; Lactic Acid; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Genetic; Mutagenesis, Insertional; Mutation; Pyruvaldehyde | 2007 |
Formate excretion in urine of rats fed dimethylaminoazobenzene-rich diets: the possibility of formate formation from D-lactate.
Topics: Acetaldehyde; Administration, Oral; Animals; Body Mass Index; Cysteine; Diet; Drinking; Eating; Formates; Glutathione; Lactic Acid; Lactoylglutathione Lyase; Liver; Male; p-Dimethylaminoazobenzene; Pyruvaldehyde; Rats; Rats, Inbred Strains; Thiolester Hydrolases | 2008 |
Enhanced methylglyoxal formation in the erythrocytes of hemodialyzed patients.
Topics: Adult; Case-Control Studies; Erythrocytes; Female; Glutathione; Humans; Kidney Failure, Chronic; Lactic Acid; Lactoylglutathione Lyase; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Tandem Mass Spectrometry; Thiolester Hydrolases | 2009 |
Effects of glyoxal or methylglyoxal on the metabolism of amino acids, lactate, glucose and acetate in the cerebral cortex of young and adult rats.
Topics: Acetates; Aging; Amino Acids; Animals; Carbon Dioxide; Central Nervous System Agents; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glutamine; Glycine; Glyoxal; Lactic Acid; Lipid Metabolism; Male; Oxidation-Reduction; Protein Biosynthesis; Pyruvaldehyde; Rats; Rats, Wistar | 2010 |
[Methylglyoxal--a test for impaired biological functions of exotrophy and endoecology, low glucose level in the cytosol and gluconeogenesis from fatty acids (a lecture)].
Topics: Animals; Cytosol; Diabetes Mellitus; Diabetic Ketoacidosis; Energy Metabolism; Fatty Acids; Gluconeogenesis; Glucose; Humans; Ketone Bodies; Lactic Acid; Neoplasms; Nucleic Acid Denaturation; Protein Denaturation; Pyruvaldehyde; Renal Insufficiency | 2010 |
Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Bicarbonates; Blood Glucose; Diabetic Ketoacidosis; Female; Humans; Lactic Acid; Male; Middle Aged; Pyruvaldehyde | 2011 |
Determination of time-dependent accumulation of D-lactate in the streptozotocin-induced diabetic rat kidney by column-switching HPLC with fluorescence detection.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Histocytochemistry; Kidney; Kidney Cortex; Lactic Acid; Linear Models; Male; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Stereoisomerism; Streptozocin; Time Factors | 2011 |
Mitochondrial involvement to methylglyoxal detoxification: D-Lactate/Malate antiporter in Saccharomyces cerevisiae.
Topics: Aerobiosis; Antiporters; Inactivation, Metabolic; Lactic Acid; Malates; Mitochondria; Mitochondrial Membranes; Pyruvaldehyde; Saccharomyces cerevisiae | 2012 |
Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells.
Topics: Cell Line, Tumor; Coloring Agents; Energy Metabolism; Glioma; Glucose; Glycation End Products, Advanced; Glycine; Humans; Lactic Acid; Lactoylglutathione Lyase; Neutral Red; Oxidation-Reduction; Propidium; Pyruvaldehyde; Tetrazolium Salts; Thiazoles; Thiolester Hydrolases | 2012 |
Clinical and forensic examinations of glycaemic marker methylglyoxal by means of high performance liquid chromatography-tandem mass spectrometry.
Topics: Adult; Biomarkers; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus; Diabetic Coma; Female; Forensic Pathology; Glucose; Humans; Lactic Acid; Male; Middle Aged; Postmortem Changes; Pyruvaldehyde; Tandem Mass Spectrometry; Vitreous Body | 2013 |
Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli.
Topics: Bacterial Proteins; Escherichia coli; Glycerol; Glycerol Kinase; Glycerolphosphate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Metabolic Engineering; Phosphotransferases (Alcohol Group Acceptor); Pyruvaldehyde; Stereoisomerism; Streptococcus bovis; Sugar Alcohol Dehydrogenases | 2013 |
D-Lactate production as a function of glucose metabolism in Saccharomyces cerevisiae.
Topics: Aerobiosis; Computer Simulation; Culture Media; Glucose; Lactic Acid; NAD; Pyruvaldehyde; Saccharomyces cerevisiae; Trioses | 2013 |
Dimerumic acid attenuates receptor for advanced glycation endproducts signal to inhibit inflammation and diabetes mediated by Nrf2 activation and promotes methylglyoxal metabolism into d-lactic acid.
Topics: Animals; Antioxidants; Diabetes Mellitus; Diketopiperazines; Glucose; Glycation End Products, Advanced; Humans; Hydroxamic Acids; Inflammation; Insulin; Lactic Acid; Leukocytes, Mononuclear; Liver; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Tumor Necrosis Factor-alpha | 2013 |
'Chiral compartmentation' in metabolism: enzyme stereo-specificity yielding evolutionary options.
Topics: Erythrocytes; Evolution, Molecular; Humans; Kinetics; Lactic Acid; Lactoylglutathione Lyase; Magnetic Resonance Spectroscopy; Pyruvaldehyde; Stereoisomerism; Substrate Specificity | 2013 |
Acute glutathione depletion induces hepatic methylglyoxal accumulation by impairing its detoxification to D-lactate.
Topics: Adipose Tissue; Animals; Buthionine Sulfoximine; Glutathione; Inactivation, Metabolic; Lactic Acid; Lactoylglutathione Lyase; Liver; Male; Models, Animal; Oxidative Stress; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiolester Hydrolases | 2013 |
Methylglyoxal resistance in Bacillus subtilis: contributions of bacillithiol-dependent and independent pathways.
Topics: Bacillus subtilis; Cysteine; Cytoplasm; Drug Resistance, Bacterial; Glucosamine; Hydrogen-Ion Concentration; Lactic Acid; Lactoylglutathione Lyase; Metabolic Networks and Pathways; Pyruvaldehyde; Thiolester Hydrolases | 2014 |
Methylglyoxal concentrations differ in standard and washed neonatal packed red blood cells.
Topics: Adenine; Animals; Blood Glucose; Blood Preservation; Enterocolitis, Necrotizing; Erythrocytes; Glucose; Glutathione; Humans; Infant, Newborn; Infant, Premature; Lactic Acid; Lactoylglutathione Lyase; Mannitol; Preservatives, Pharmaceutical; Pyruvaldehyde; Sodium Chloride; Transfusion Reaction | 2014 |
Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures.
Topics: Acetals; Amino Acid Sequence; Carbon-Sulfur Lyases; Catalysis; Crystallography, X-Ray; Lactic Acid; Molecular Sequence Data; Protein Conformation; Pyruvaldehyde; Stereoisomerism | 2014 |
Dihydromyricetin ameliorates the oxidative stress response induced by methylglyoxal via the AMPK/GLUT4 signaling pathway in PC12 cells.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Calcium; Cell Membrane; Cell Survival; Dose-Response Relationship, Drug; Flavonols; Gene Expression Regulation; Glucose; Glucose Transporter Type 4; Glutathione; In Situ Nick-End Labeling; Lactic Acid; Oxidative Stress; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Signal Transduction | 2014 |
Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process.
Topics: alpha-Synuclein; Amino Acid Sequence; Catalytic Domain; Heat-Shock Proteins; Humans; Lactic Acid; Lactoylglutathione Lyase; Molecular Sequence Data; Oxidative Stress; Prions; Protein Aggregates; Protein Folding; Protein Multimerization; Protein Structure, Quaternary; Pyruvaldehyde; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2015 |
d-Lactate Dehydrogenase Links Methylglyoxal Degradation and Electron Transport through Cytochrome c.
Topics: Arabidopsis; Arabidopsis Proteins; Biocatalysis; Blotting, Western; Cells, Cultured; Cytochromes c; Electron Transport; L-Lactate Dehydrogenase; Lactic Acid; Mass Spectrometry; Microscopy, Confocal; Mitochondrial Membranes; Mutation; Oxidation-Reduction; Oxygen Consumption; Plants, Genetically Modified; Pyruvaldehyde; Pyruvic Acid | 2016 |
Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.
Topics: Acetylcysteine; Aldehydes; Amino Acid Sequence; beta-Alanine; Coenzyme A; Glutathione; HeLa Cells; Humans; Inactivation, Metabolic; Lactic Acid; Mutant Proteins; Mutation; Parkinson Disease; Protein Deglycase DJ-1; Pyruvaldehyde; Recombinant Proteins; Sequence Homology, Amino Acid; Structural Homology, Protein; Sulfhydryl Compounds | 2017 |
Higher D-lactate levels are associated with higher prevalence of small dense low-density lipoprotein in obese adolescents.
Topics: Adolescent; Biomarkers; Body Mass Index; Carotid Intima-Media Thickness; Cross-Sectional Studies; Dyslipidemias; Female; Humans; Insulin; Insulin Resistance; Lactic Acid; Lipoproteins, LDL; Male; Mexico; Obesity; Pyruvaldehyde; Stereoisomerism; Young Adult | 2018 |
Trypanosoma brucei aquaglyceroporins mediate the transport of metabolic end-products: Methylglyoxal, D-lactate, L-lactate and acetate.
Topics: Acetates; Aquaglyceroporins; Biological Transport; Glycerol; Glycolysis; Lactic Acid; Pyruvaldehyde; Pyruvic Acid; Stereoisomerism; Trypanosoma brucei brucei | 2018 |
Profiling of Methylglyoxal Blood Metabolism and Advanced Glycation End-Product Proteome Using a Chemical Probe.
Topics: Amino Acid Sequence; Blood Proteins; Erythrocytes; Glycation End Products, Advanced; HeLa Cells; Humans; Lactic Acid; Protein Processing, Post-Translational; Proteome; Proteomics; Pyruvaldehyde | 2018 |
Isocaloric Fructose Restriction Reduces Serum d-Lactate Concentration in Children With Obesity and Metabolic Syndrome.
Topics: Adipose Tissue; Adolescent; Black or African American; Carbon-13 Magnetic Resonance Spectroscopy; Child; Dietary Carbohydrates; Dietary Sugars; Female; Fructose; Glucose Tolerance Test; Hispanic or Latino; Humans; Insulin Resistance; Lactic Acid; Lipogenesis; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolic Syndrome; Pediatric Obesity; Pyruvaldehyde; Triglycerides | 2019 |
Effect of Cysteine on Methylglyoxal-Induced Renal Damage in Mesangial Cells.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cell Survival; Cysteine; Guanidines; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lactoylglutathione Lyase; MAP Kinase Signaling System; Mesangial Cells; Mice; Pyruvaldehyde; Reactive Oxygen Species; Sirtuin 1 | 2020 |
Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass spectrometry.
Topics: Animals; Aristolochic Acids; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Fibrosis; Fructose-Bisphosphate Aldolase; Humans; Inflammation; Kidney; Kidney Diseases; Lactic Acid; Lactoylglutathione Lyase; Mice; Prednisolone; Proteomics; Pyruvaldehyde; Tandem Mass Spectrometry; Triose-Phosphate Isomerase | 2020 |
Optimized sensitive and inexpensive method to measure D-lactate as a surrogate marker of methylglyoxal fluxes in metabolically relevant contexts.
Topics: Biomarkers; Colorimetry; Humans; Lactic Acid; Pyruvaldehyde; Sepsis | 2022 |
Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Chromatography, Liquid; Cisplatin; Female; Kidney; Lactic Acid; Mice, Inbred BALB C; Oxidative Stress; Pyruvaldehyde; Tandem Mass Spectrometry | 2020 |
Utilizing methylglyoxal and D-lactate in urine to evaluate saikosaponin C treatment in mice with accelerated nephrotoxic serum nephritis.
Topics: Animals; Glomerulonephritis; Lactic Acid; Mice; Mice, Inbred C57BL; Oleanolic Acid; Pyruvaldehyde; Saponins | 2020 |
Evaluation of the nephrotoxicity and safety of low-dose aristolochic acid, extending to the use of Xixin (Asurum), by determination of methylglyoxal and d-lactate.
Topics: Animals; Aristolochic Acids; Collagen; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fibrosis; Kidney Diseases; Kidney Tubules; Lactic Acid; Lactoylglutathione Lyase; Mice, Inbred C3H; Pyruvaldehyde | 2021 |
Systemic inflammation down-regulates glyoxalase-1 expression: an experimental study in healthy males.
Topics: Adolescent; Adult; Biomarkers; Down-Regulation; Endotoxemia; Healthy Volunteers; Humans; Hypoxia; Inflammation; Lactic Acid; Lactoylglutathione Lyase; Male; Pyruvaldehyde; Young Adult | 2021 |
Loss of glyoxalase 2 alters the glucose metabolism in zebrafish.
Topics: Animals; Glucose; Lactic Acid; Lactoylglutathione Lyase; Pyruvaldehyde; Thiolester Hydrolases; Zebrafish | 2023 |
Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ-1.
Topics: Aldehyde Oxidoreductases; Humans; Lactic Acid; Parkinson Disease; Protein Deglycase DJ-1; Pyruvaldehyde | 2023 |
PARK7 Catalyzes Stereospecific Detoxification of Methylglyoxal Consistent with Glyoxalase and Not Deglycase Function.
Topics: Humans; Lactic Acid; Magnesium Oxide; Parkinson Disease; Protein Deglycase DJ-1; Pyruvaldehyde | 2023 |