lactic acid has been researched along with paclitaxel in 228 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (1.75) | 18.2507 |
| 2000's | 76 (33.33) | 29.6817 |
| 2010's | 139 (60.96) | 24.3611 |
| 2020's | 9 (3.95) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Arsenault, AL; Bains, SK; Burt, HM; Hunter, WL; Jackson, JK; Liggins, RT; Oktaba, AM | 1 |
| Adachi, I; Horikoshi, I; Sato, H; Wang, YM | 2 |
| Jeong, B; Kim, SW; Rathi, R; Suh, H | 1 |
| Burt, HM; D'Amours, S; Demetrick, JS; Liggins, RT; Machan, LS | 1 |
| Feng, S; Huang, G | 1 |
| Bang, JS; Kim, DW; Kim, SC; Oh, HS; Seo, MH; Shim, YH; Wan Kim, S | 1 |
| Burt, HM; Liggins, RT | 3 |
| Feng, SS; Mu, L | 3 |
| Fonseca, C; Gaspar, R; Simões, S | 1 |
| Bian, X; Chen, X; Jing, X; Liang, Q; Xu, X; Yang, L; Zeng, J | 1 |
| Brouse, CF; Eberhart, RC; Greilich, PE; Nguyen, KT; Schwade, ND; Sheng, A; Su, SH; Tang, L; Wawro, D | 1 |
| Ciftci, K; Gupte, A | 1 |
| Eberhart, RC; Nguyen, KT; Schwade, ND; Shaikh, N; Tang, L; Wawro, D; Zhang, S | 1 |
| Deng, LD; Dong, AJ; Jin, JZ; Sun, DX; Yuan, YJ; Zhang, YT | 1 |
| Baek, N; Lee, J; Park, K | 1 |
| Babiuk, KA; Burt, HM; Hunter, WL; Jackson, JK; Letchford, K; Machan, L; Signore, P; Smith, J; Wang, K | 1 |
| Cho, SH; Chon, SK; Jeong, SY; Kang, BK; Khang, G; Kim, MS; Kim, SH; Lee, HB | 1 |
| Fens, M; Hennink, WE; Rijcken, CJ; Schiffelers, RM; Soga, O; Storm, G; van Nostrum, CF | 1 |
| Cho, SH; Kim, BK; Kim, D; Yuk, SH | 1 |
| Wang, G; Yin, T | 1 |
| Dong, Y; Feng, SS | 2 |
| De, S; Miller, DW; Robinson, DH | 1 |
| Feng, SS; Zhang, Z | 1 |
| Lim, LY; Mo, Y | 1 |
| Wang, CH; Xie, J | 2 |
| Feng, SS; Win, KY | 1 |
| Greiner, A; Hanefeld, P; Hellwig, M; Kissel, T; Schaper, AK; Westedt, U; Wittmar, M | 1 |
| Arica-Yegin, B; Benoit, JP; Elkharraz, K; Faisant, N; Goepferich, A; Guse, C; Gust, R; Oger, JM; Siepmann, F; Siepmann, J | 1 |
| Bhargava, B; Karthikeyan, G; Mishra, S; Raju, R; Reddy, NK; Singh, S; Somaraju, B; Virmani, R; Waksman, R | 1 |
| Chavanpatil, MD; Panyam, J; Patil, Y | 1 |
| Liu, SQ; Tong, YW; Yang, YY | 1 |
| Ciach, T | 1 |
| Kraitzer, A; Zilberman, M | 1 |
| Bai, L; Guo, G; Jin, C; Liu, J; Wu, H | 1 |
| Bakowsky, U; Fuchs, J; Kalinowski, M; Kissel, T; Merdan, T; Schäller, S; Unger, F; Westedt, U; Wittmar, M | 1 |
| Hu, T; Xie, M; Yao, M; Zhou, L | 1 |
| Chang, DH; Kim, BO; Kim, SO; Lee, SW; Seo, MH; Shim, MS | 1 |
| Johnston, MR; Kwong, E; Liu, J; Meisner, D; Wu, XY | 2 |
| Bai, L; Guo, G; Jin, C; Tian, F; Wu, H | 1 |
| Che, YZ; Jin, X; Jin, Z; Mei, L; Song, CX; Sun, HF | 1 |
| Burt, HM; Hung, T; Jackson, JK; Letchford, K | 1 |
| Burt, HM; Gleave, ME; Jackson, JK; Lu, J | 1 |
| Chen, H; Dai, J; Gao, J; Guo, Y; Hou, S; Kou, G; Li, B; Qian, W; Wang, H; Wang, S; Zhang, D; Zhong, Y | 1 |
| Feng, SS; Ranganathan, B; Sun, B | 1 |
| Lee, LY; Smith, KA; Wang, CH | 1 |
| Lao, LL; Venkatraman, SS | 1 |
| Bai, L; Chen, J; Guo, G; Jin, C; Liu, J; Wu, H | 1 |
| Chen, H; Cheng, JX; Kim, S; Li, L; Park, K; Wang, S | 1 |
| Huang, Z; Kang, Y; Liao, X; Ouyang, P; Wang, H; Wu, J; Yang, Q; Yao, Y; Yin, G | 1 |
| Cuchet, D; Diab, R; Dumontet, C; Fessi, H; Hamoudeh, M | 1 |
| Adamo, L; Conticello, C; De Maria, R; Giannone, I; Gulisano, M; Musumeci, T; Pignatello, R; Puglisi, G; Vicari, L | 1 |
| Cheng, G; Chung, SJ; Cui, F; Kim, DD; Kim, IW; Shim, CK; Shim, WS; Yang, R; Yang, SG | 1 |
| Choung, HK; Hwang, JM; Jin, SE; Kim, CK; Lee, MJ | 1 |
| Kim, BS; Kim, CS; Lee, KM | 1 |
| Danhier, F; Feron, O; Jérôme, C; Lecouturier, N; Marchand-Brynaert, J; Préat, V; Vroman, B | 1 |
| Chen, X; Jing, X; Wang, Z; Xu, X | 1 |
| Cheng, G; Chung, SJ; Cui, FD; Han, X; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Yang, R | 1 |
| Lee, HS; Lee, LY; Lu, F; Ong, BY; Ranganath, SH; Sahinidis, NV; Wang, CH | 1 |
| Ma, L; Panyam, J; Patil, Y; Sadhukha, T | 1 |
| Jang, Y; Kim, TG; Lee, H; Park, TG | 1 |
| Bai, L; Dou, K; Guo, G; Jin, C; Song, W; Wu, H | 1 |
| Chronos, N; Conway, D; Jabara, R; Molema, W; Robinson, K | 1 |
| Li, K; Liu, Y; Liu, Z; Miyoshi, H; Yang, H | 1 |
| Fang, K; Kang, YQ; Wang, HJ; Yang, K; Yang, Q; Yin, GF | 1 |
| Eniola-Adefeso, O; Heslinga, MJ; Mastria, EM | 1 |
| Chaudhari, K; Dantuluri, P; Das, S; Murthy, RS; Shah, N | 1 |
| Chow, PK; Kee, I; Krantz, WB; Ranganath, SH; Wang, CH | 1 |
| He, CL; Huang, HH; Mo, XM; Wang, HS | 1 |
| Niu, R; Shi, Y; Wei, X; Yang, Y; Yu, M; Zang, F | 1 |
| Gao, C; Lu, W; Pan, J; Tian, J; Zhang, M; Zhou, L | 1 |
| Crokart, N; Danhier, F; Feron, O; Freichels, H; Jérôme, C; Lecouturier, N; Marchand-Brynaert, J; Pourcelle, V; Préat, V; Vroman, B | 1 |
| Gao, HX; Li, MJ; Wang, TW; Wu, Y | 1 |
| Chen, HZ; Fang, C; Lu, Q; Xie, J; Yu, DH | 1 |
| Feng, SS; Liu, Y; Pan, J | 1 |
| Cormack, R; Gultepe, E; Jost, E; Levy, CO; Makrigiorgos, GM; Nagesha, D; Singh, S; Sridhar, S; Tada, DB | 1 |
| Bende, G; Kollipara, S; Movva, S; Saha, R | 1 |
| Feng, SS; Zhao, L | 1 |
| Bin Jamali, NH; Gay, GK; Hu, Y; Lei, C; Wang, CH; Xie, J | 1 |
| Haklai, R; Kloog, Y; Kraitzer, A; Zilberman, M | 1 |
| Gong, YC; Guo, L; Li, YP; Li, ZL; Xiong, XY | 1 |
| Cho, HS; Dong, Z; Ewing, RC; Gu, H; Huth, C; Pauletti, GM; Shi, D; Wang, F; Wang, L; Xu, H; Zhang, J | 1 |
| Arifin, DY; Dong, Z; Hu, Y; Nie, H; Wang, CH | 1 |
| Ho, PC; Lim, LY; Wang, C | 1 |
| Antoniucci, D; Bernardi, V; Bettinoti, M; Curotto, V; Delacasa, A; Fernandez-Pereira, C; Mieres, J; Palacios, IF; Rodriguez, AE; Rodriguez-Granillo, AM; Rodriguez-Granillo, G; Rubilar, B; Santaera, O; Tronge, J; Vigo, CF | 1 |
| Dafni, H; Hu, S; Larson, PE; Ronen, SM; Venkatesh, HS; Vigneron, DB; Wang, C; Ward, CS; Yoshihara, HA; Zhang, X | 1 |
| Cao, L; Fan, H; Liu, Y; Lu, P; Wu, X; Xu, X | 1 |
| Bianchi, CF; Buchholz, B; Gao, F; Gu, Z; Laham, R; Ma, X; McCarthy, S; Oyamada, S; Robich, MP; Sellke, FW; Wang, X; Wu, H; Wu, T | 1 |
| Chen, KM; Guo, SR; Hou, JW; Lei, L; Liu, X; Tang, MF; Wang, ZM | 1 |
| Boey, FY; Huang, CL; Loo, JS; Steele, TW; Venkatraman, SS; Widjaja, E | 1 |
| Chakravarthi, SS; Robinson, DH | 1 |
| Acharya, S; Sahoo, SK | 1 |
| Chiang Boey, FY; Huang, CL; Kumar, S; Loo, JS; Steele, TW; Venkatraman, SS; Widjaja, E | 1 |
| Alani, AW; Bae, Y; Cho, H; Kolesar, JM; Kwon, GS; Shin, HC | 1 |
| Huang, Y; Li, T; Li, X; Liang, C; Ling, Y; Yang, Y | 1 |
| Chen, H; Chen, J; Gao, X; Gu, G; Guo, J; Jiang, X; Pang, Z; Su, L; Xia, H; Yao, L | 1 |
| Ateh, DD; Gironès, M; Ibrahim, NI; Johnstone, JV; Kadam, MM; Khan, A; Lambert, SR; Leinster, VH; Malik, Z; Marino, S; Martin, JE; McNeish, IA; Shah, A; Veldhuis, GJ; Walklin, HJ; Warnes, G | 1 |
| Liu, Y; Yan, B; Zhang, B | 1 |
| Ensign, L; Hanes, J; Lai, SK; Mert, O; Wang, YY; Wood, J; Yang, M | 1 |
| Parveen, S; Sahoo, SK | 1 |
| Harilal, A; Krishnakumar, S; Misra, R; Mitra, M; Sahoo, SK | 1 |
| Hu, X; Jing, X; Liu, S; Song, X; Wan, Y; Zheng, Y | 1 |
| He, B; Li, Z; Liu, C; Long, L; Sheng, J; Wang, J; Wang, L; Yuan, X | 1 |
| Sharma, G; She, ZG; Smith, JW; Wang, S; Xie, H | 1 |
| Fu, Q; Tang, S; Yan, F | 1 |
| Cho, YW; Choi, JS; Choi, YC; Kim, JD; Lee, BK; Yun, YH | 1 |
| Chang, J; Han, J; Ji, W; Liao, Z; Niu, R; Wang, H; Wang, X; Wu, B; Yu, M; Zhang, F; Zhang, H; Zhao, P | 1 |
| Alyautdin, RN; Balaban'yan, VY; Baranov, DS; Bojat, V; Hamdy, YM; Oganesyan, EA | 1 |
| Amoozgar, Z; Lin, Q; Park, J; Yeo, Y | 1 |
| Gullotti, E; Yeo, Y | 1 |
| Beck-Broichsitter, M; Bege, N; Curdy, C; Endres, T; Kissel, T; Librizzi, D; Merkel, O; Petersen, H; Renette, T | 1 |
| Grill, AE; Guru, BR; Kalscheuer, S; Kirtane, A; Panyam, J; Roger, E; Whittum-Hudson, J | 1 |
| Adamson, DH; Ansell, SM; D'Addio, SM; Herrera-Alonso, M; Hoye, TR; Macosko, CW; Mayer, LD; Prud'homme, RK; Saad, W; Squiers, JJ; Vauthier, C; Wohl, AR | 1 |
| Araki, T; Higaki, K; Kimura, T; Kono, Y; Ogawara, K; Ono, T; Watanabe, T | 1 |
| Cheng, FY; Shieh, DB; Su, WC; Su, WP; Yeh, CS | 1 |
| Chen, LC; da Silva Coelho, L; de Souza, DC; Guillo, LA; Vieira, IL | 1 |
| Jin, SH; Li, NC; Na, YQ; Zhang, ZH | 1 |
| Bhaskar, S; Roy, A; Singh, MS; Upadhyay, P | 1 |
| Huang, B; Liu, CS; Wang, G; Wu, Y; Yu, B; Yuan, Y | 1 |
| Durocher, A; Fayad, G; Koussa, M; Marechal, X; Modine, T; Montaigne, D; Neviere, R; Preau, S; Saulnier, F; Tardivel, M | 1 |
| Danhier, F; Danhier, P; Gallez, B; Jérôme, C; Laurent, S; Muller, RN; Préat, V; Schleich, N; Sibret, P; Ucakar, B | 1 |
| Dhanda, DS; Kompella, UB; Mirvish, SS; Tyagi, P | 1 |
| Gullotti, E; Park, J; Yeo, Y | 1 |
| Betbeder, D; Carpentier, R; Daher, S; Furman, C; Le Broc-Ryckewaert, D; Lipka, E; Vaccher, C | 1 |
| Benita, S; Borlak, J; Karra, N; Nassar, T; Ripin, AN; Schwob, O | 1 |
| Dai, T; Gao, Z; Li, S; Liu, L; Shen, N; Sun, Y; Wu, S; Xie, Y; Yang, E; Zhang, L | 1 |
| Han, J; Hoye, TR; Lee, HS; Macosko, CW; McCormick, AV; Michel, AR; Panyam, J; Pustulka, KM; Wohl, AR | 1 |
| Au, JL; Lu, Z; Tsai, M; Wientjes, MG | 1 |
| Deng, R; Dong, L; Liang, R; Liu, S; Sullivan, M; Tao, J; Wang, J; Wang, K; Wu, M; Wu, X; Yang, X; Zhu, J | 1 |
| Chen, Y; Kong, D; Liu, C; Song, C; Sun, H; Wang, C; Yang, J; Yang, Z; Zhang, Z; Zhao, S | 1 |
| Park, K | 1 |
| Lu, Y; Park, K; Sturek, M | 1 |
| Manzoor, K; Menon, D; Mohan, CC; Narayanan, D; Narayanan, S; Pavithran, M; Viswanath, A | 1 |
| Eniola-Adefeso, O; Heslinga, MJ; Sobczynski, DJ; Thompson, AJ; Willis, GM | 1 |
| Chen, XG; He, YX; Li, R; Wang, XY; Yang, WY; Yang, X; Zhang, Q | 1 |
| Chen, T; Huang, F; Liang, H; Tan, W; You, M; Zhu, G | 1 |
| Chen, H; Chen, J; Feng, X; Gao, X; Hu, Q; Huang, M; Jiang, D; Jiang, X; Kang, T; Pang, Z; Song, Q; Yao, L; Zhang, X | 1 |
| Ahamed, HN; Saha, RN; VasanthaKumar, S | 1 |
| Chen, J; Feng, G; He, S; Jiang, X; Kislauskis, E; Laham, R; Lan, Z; Lyu, Y; McCarthy, S; Wang, S; Wu, T; Xiao, J; Zhang, Y; Zheng, X | 1 |
| Kong, Y; Qiu, X; Wang, T; Wang, Y; Zhang, J | 1 |
| Alam, N; Dubey, RD; Gupta, PN; Jain, S; Khare, V; Kour, S; Nehate, C; Saneja, A; Singh, SK | 1 |
| Kao, LT; Lin, WJ | 1 |
| Cao, J; Choi, HK; Choi, JS; Hasan, N; Naeem, M; Noh, J; Yoo, JW | 1 |
| Danhier, F; Gallez, B; Jacobs, D; Po, C; Préat, V; Schleich, N; Ucakar, B | 1 |
| Chang, SH; Chen, WJ; Hsieh, IC; Hsu, MY; Hung, KC; Ko, YS; Lee, CH; Liu, SJ; Wang, CJ; Wen, MS; Yu, CY | 1 |
| Amoozgar, Z; Brandstoetter, T; Goldberg, MS; Wallis, SS; Wang, L; Wilson, EM | 1 |
| Chen, X; Feng, T; Lam, MH; Liang, H; Lin, L; Tian, H; Xie, Z; Xu, C | 1 |
| Feng, SS | 1 |
| Cao, S; Jiang, X; Wang, F; Wang, Y; Wei, Y; Xiong, Y; Xu, S; Zhang, Q; Zhang, S; Zou, A | 1 |
| Limtrakul, P; Naiki, T; Pitchakarn, P; Punfa, W; Suzuki, S; Takahashi, S; Yodkeeree, S | 1 |
| Chen, Y; Lee, RJ; Sun, Y; Tang, S; Teng, L; Wang, G; Wu, Y; Xu, S; Yu, B; Yuan, Y; Zhang, X | 1 |
| Du, LF; Duan, YR; Gao, F; Jin, LF; Li, F; Li, Z; Ma, J; Shen, M; Su, Y; Xing, LX; Zhu, MJ | 1 |
| Ding, Y; Ji, T; Li, Y; Nie, G; Su, S; Tian, Y; Wu, M; Wu, Y | 1 |
| Azzariti, A; Cocco, T; Ferretta, A; Guida, G; Guida, M; Guida, S; Iacobazzi, RM; Maida, I; Porcelli, L; Quatrale, AE; Sidella, L; Stolfa, DA; Strippoli, S; Tommasi, S | 1 |
| Du, YZ; Hu, FQ; Li, WS; Liu, P; Shan, CL; Situ, JQ; You, J; Yuan, H | 1 |
| Hou, ZH; Zhang, Q; Zhao, WC; Zheng, W | 1 |
| Chen, C; Chen, X; Fan, Z; Fang, X; Liang, H; Pang, X; Qi, Y; Sha, X; Yu, Z | 1 |
| Wang, B; Xu, M; Xu, SF; Yu, XC | 1 |
| Bai, T; Chen, Z; Cui, H; Gu, N; Myers, JN; Song, L; Yang, F; Zhang, X; Zhou, Y | 1 |
| Koyakutty, M; Menon, D; Mony, U; Narayanan, S; Paul-Prasanth, B; Vijaykumar, DK | 1 |
| Amini, M; Atyabi, F; Darvishi, B; Dinarvand, R; Esfandyari-Manesh, M; Koopaei, MN; Majidi, RF; Mostafavi, SH; Ostad, SN; Ravari, NS | 1 |
| Arya, N; Katti, DS | 1 |
| He, J; Ni, P; Ren, K; Wu, Y; Zhang, M | 1 |
| Lu, W; Shi, Y; Zhang, J; Zhou, M | 1 |
| Gires, O; Kämmerer, U; Klement, RJ; Otto, C; Pfetzer, N; Wiegering, A | 1 |
| Ferdous, J; Kolachalama, VB; Kolandaivelu, K; Shazly, T | 1 |
| Chen, Y; Liu, W; Wei, J; Wei, Y | 1 |
| Chong, HC; Guo, WM; Ho, VHB; Lee, WL; Loo, SCJ; Saha, A; Tan, EY; Tan, NS | 1 |
| Alipour, S; Montaseri, H; Tafaghodi, M | 1 |
| Heo, MB; Kim, SY; Lim, YT; Yun, WS | 1 |
| Chen, J; Feng, G; Huo, Z; Jiang, X; Kang, G; Kislauskis, E; Laham, R; Lan, Z; Liao, T; McCarthy, S; Wang, Q; Wang, Z; Wu, T; Xi, T; Xia, J; Xiao, J | 1 |
| Gao, Y; Li, Y; Teng, L; Yu, K; Zhang, Z; Zhao, J; Zhou, Y | 1 |
| An, T; Li, R; Wan, G; Wang, D; Wang, H; Wang, Y; Yang, X; Zhang, C; Zhang, M; Zhang, S | 1 |
| Chuttani, K; Ghanghoria, R; Jain, NK; Mishra, AK; Tekade, RK | 1 |
| Khan, W; Kumar, R; Muntimadugu, E; Rafeeqi, TA; Saladi, S | 1 |
| Anuku, N; Danyuo, Y; Dozie-Nwachukwu, S; Malatesta, K; Obayemi, JD; Odusanya, OS; Soboyejo, WO; Uhrich, KE; Yu, W | 1 |
| Cao, Z; Ge, X; Gu, Y; Han, M; Li, J; Lyu, P; Wang, F; Xia, W; Yu, Z | 1 |
| Deng, C; Meng, F; Wu, J; Zhang, J; Zhong, Z | 1 |
| Bao, Y; Chen, S; Chu, Q; Ji, W; Lu, S; Tan, S; Wu, K; Yuan, X | 1 |
| Cui, Y; Huang, Y; Jin, H; Xu, Q; Zeng, F; Zhang, M | 1 |
| Atila Dinçer, C; Aydoğan, N; Çalimli, A; Karakeçili, A; Yildiz, N | 1 |
| Bikiaris, DN; Giliopoulos, DJ; Kostoglou, M; Nanaki, S; Nerantzaki, M; Nikolakaki, E; Siafaka, PI; Triantafyllidis, KS; Zachariadou, D | 1 |
| Do, L; Dou, H; Payne, G; Rodriguez, J; Tao, Y; Thomas, T; Zou, L | 1 |
| Bharali, DJ; Darwish, NH; Davis, PJ; Debreli Coskun, M; Keating, KA; Lin, HY; Mousa, SA; Sudha, T; Yalcin, M | 1 |
| Danyuo, Y; Dozie-Nwachukwu, S; E Oberaifo, O; J Ani, C; Malatesta, K; Obayemi, JD; Odusanya, OS; Soboyejo, WO; Zebaze Kana, MG | 1 |
| Chang, CW; Chen, HH; Chiang, CS; Chiang, WH; Chiu, HC; Huang, WC; Lin, YW; Lu, IL; Tsai, YC | 1 |
| Chen, H; Li, R; Liu, B; Qian, H; Qian, X; Shao, J; Su, S; Wang, L; Wei, J; Zhang, L | 1 |
| Barczyk, A; Betbeder, D; Carpentier, R; Chavatte, P; Furman, C; Lipka, E | 1 |
| Chen, M; Chen, S; Fai Chan, H; He, C; Wang, L; Wang, Y; Xie, W; Zhang, J | 1 |
| Al-Kassas, R; Cerqueira, BBS; Lasham, A; Shelling, AN | 1 |
| Ceaglio, N; Dubruel, P; Luna, J; Mogosanu, DE; Navarro, L; Rintoul, I | 1 |
| Chen, H; Chen, X; Fan, A; Guo, C; Kong, Y; Li, N; Liu, Q; Lu, Y; Xu, J; Yang, Y; Zhang, Q; Zhao, D; Zhu, X | 1 |
| Cui, YN; Davoodi, P; Wang, CH; Wang, DP; Xu, QX | 1 |
| Du, Y; Fu, Q; Ganapathy, V; He, Z; Kou, L; Luo, Q; Sun, J; Sun, M; Wang, G; Wang, J; Wu, C; Yao, Q | 1 |
| Cheng, F; Gong, YC; Li, YP; Li, ZL; Luo, YY; Xiong, XY | 1 |
| Kim, JO; Nguyen, CN; Nguyen, HT; Tran, BN; Yong, CS | 1 |
| Hao, L; Luo, Y; Tang, J; Wang, D; Wang, Y; Wang, Z; Wu, M; Zhang, M | 1 |
| Chai, Z; Gao, B; Guan, J; Hu, X; Liu, J; Liu, X; Lu, W; Qian, J; Yang, Y; Zhan, C; Zhang, Z | 1 |
| Ashford, M; d'Arcy, R; De La Rosa, JMR; Donno, R; Gennari, A; Hill, K; Lallana, E; Tirelli, N; Treacher, K | 1 |
| Li, F; Li, Y; Liu, N; Qin, S; Sun, X; Teng, L; Yu, K; Zhao, C; Zhou, Y | 1 |
| Hou, Y; Li, B; Wang, X; Yang, J; Yi, L; Zhang, Z | 1 |
| Bandyopadhyay, AK; Dey, G; Mandal, D; Mandal, M; Mukherjee, B; Pal, MM; Shaw, TK | 1 |
| Chen, JK; Hsieh, IC; Hsieh, MJ; Hung, KC; Lee, CH; Liu, SC; Liu, SJ; Wen, MS | 1 |
| Makino, K; Mikuni, R; Takeuchi, I | 1 |
| Han, T; Hao, J; Liu, J; Tang, H; Wang, M; Wang, X; Wang, Y; Zhuang, Q | 1 |
| Bastiancich, C; Bianco, J; Danhier, F; Gallez, B; Ganipineni, LP; Jankovski, A; Joudiou, N; Préat, V; Rieux, AD; Tsakiris, N; Zhao, M | 1 |
| Bastiancich, C; Bianco, J; Danhier, F; Danhier, P; Gallez, B; Ganipineni, LP; Joudiou, N; Préat, V; Ucakar, B; Zhao, M | 1 |
| Cao, Y; Chen, Y; Gong, Y; Guo, Y; Li, P; Li, Y; Liu, F; Ran, H; Wang, Z | 1 |
| Gao, J; Lv, Y; Ouyang, X; Sun, X; Wang, J; Wang, X | 1 |
| Chow, PK; Davoodi, P; Lei, C; Wang, CH; Zhan, W | 1 |
| Hara, M; Ishida, T; Miki, Y; Sasano, H; Sato, A; Suzuki, T; Takagi, K; Yoshimura, A | 1 |
| Kwon, GS; Lee, HJ; Rasoulianboroujeni, M; Repp, L | 1 |
| Cichoń, T; Janeczek, H; Jaworska, J; Kaczmarczyk, B; Karpeta-Jarząbek, P; Kasperczyk, J; Kordyka, A; Musiał-Kulik, M; Pastusiak, M; Smolarczyk, R; Stojko, M; Włodarczyk, J | 1 |
| Choi, S; Jeong, JY; Kim, D; Park, GB; Yoon, YS | 1 |
| Amani, A; Dustparast, M; Ebrahimi, HA; Noruzpour, M; Zakaria, RA | 1 |
| Ali, MY; Ebeid, K; Griguer, C; Naguib, Y; Oliva, C; Quarterman, JC; Salem, AK; Wiwatchaitawee, K | 1 |
| Cai, JX; Li, YJ; Liu, JH; Qiu, XH; Wu, JY; Xiang, DX; Xu, P; Xu, WJ | 1 |
| Bao, Y; Ishida, A; Maeki, M; Tani, H; Tokeshi, M | 1 |
| Chen, X; Feng, Y; Lu, W; Xi, Y; Xie, X; Xu, S; Zhang, S; Zhang, X; Zhou, C | 1 |
| Bajbouj, K; Haider, M; Hamda, M; Jagal, J; Okendo, J; Sahnoon, L; Semreen, MH; Sharaf, BM; Soares, NC | 1 |
3 review(s) available for lactic acid and paclitaxel
| Article | Year |
|---|---|
[Research progress of the drug-coated stents].
Topics: Angioplasty, Balloon, Coronary; Coated Materials, Biocompatible; Coronary Restenosis; Drug Delivery Systems; Humans; Lactic Acid; Paclitaxel; Pharmaceutical Preparations; Polyesters; Polymers; Sirolimus; Stents | 2005 |
Preparation of core-shell biodegradable microfibers for long-term drug delivery.
Topics: Drug Delivery Systems; Humans; Lactic Acid; Paclitaxel; Polyesters; Polymers; Trifluoroethanol | 2009 |
Enabling anticancer therapeutics by nanoparticle carriers: the delivery of Paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Drug Carriers; Humans; Lactic Acid; Magnetite Nanoparticles; Metal Nanoparticles; Nanoparticles; Nanotubes, Carbon; Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2011 |
1 trial(s) available for lactic acid and paclitaxel
| Article | Year |
|---|---|
Efficacy and safety of a double-coated paclitaxel-eluting coronary stent: the EUCATAX trial.
Topics: Aged; Angioplasty, Balloon, Coronary; Argentina; Cardiovascular Agents; Chi-Square Distribution; Coated Materials, Biocompatible; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Drug-Eluting Stents; Female; Glycocalyx; Humans; Kaplan-Meier Estimate; Lactic Acid; Logistic Models; Male; Metals; Middle Aged; Myocardial Infarction; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proportional Hazards Models; Prospective Studies; Prosthesis Design; Risk Assessment; Risk Factors; Severity of Illness Index; Stents; Thrombosis; Time Factors; Treatment Outcome | 2011 |
224 other study(ies) available for lactic acid and paclitaxel
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Controlled delivery of taxol from microspheres composed of a blend of ethylene-vinyl acetate copolymer and poly (d,l-lactic acid).
Topics: Animals; Chick Embryo; Delayed-Action Preparations; In Vitro Techniques; Lactates; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Neovascularization, Pathologic; Paclitaxel; Polymers; Polyvinyls | 1995 |
Preparation and characterization of poly(lactic-co-glycolic acid) microspheres for targeted delivery of a novel anticancer agent, taxol.
Topics: Adsorption; Antineoplastic Agents, Phytogenic; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Myristates; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 1996 |
Pharmacokinetic study of taxol-loaded poly(lactic-co-glycolic acid) microspheres containing isopropyl myristate after targeted delivery to the lung in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Drug Carriers; Lactic Acid; Lung; Male; Mice; Mice, Inbred Strains; Microscopy, Electron, Scanning; Microspheres; Myristates; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tissue Distribution | 1996 |
Regulation of smooth muscle cell proliferation using paclitaxel-loaded poly(ethylene oxide)-poly(lactide/glycolide) nanospheres.
Topics: Animals; Biocompatible Materials; Cattle; Cell Division; Cells, Cultured; Lactic Acid; Microscopy, Confocal; Microspheres; Muscle, Smooth, Vascular; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 1998 |
Paclitaxel loaded poly(L-lactic acid) microspheres for the prevention of intraperitoneal carcinomatosis after a surgical repair and tumor cell spill.
Topics: Animals; Carbon Dioxide; Cecum; Drug Delivery Systems; Glioblastoma; Insufflation; Intraoperative Complications; Lactic Acid; Male; Microspheres; Paclitaxel; Peritoneal Cavity; Polyesters; Polymers; Rats; Rats, Wistar | 2000 |
Effects of emulsifiers on the controlled release of paclitaxel (Taxol) from nanospheres of biodegradable polymers.
Topics: Antineoplastic Agents, Phytogenic; Delayed-Action Preparations; Drug Compounding; Electrochemistry; Emulsions; Excipients; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Paclitaxel; Particle Size; Phospholipids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Surface Properties | 2001 |
In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Compounding; Female; Humans; Lactic Acid; Lethal Dose 50; Male; Mice; Mice, Nude; Micelles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tumor Cells, Cultured | 2001 |
Paclitaxel loaded poly(L-lactic acid) microspheres: properties of microspheres made with low molecular weight polymers.
Topics: Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Lactic Acid; Microspheres; Molecular Weight; Paclitaxel; Polyesters; Polymers | 2001 |
Fabrication, characterization and in vitro release of paclitaxel (Taxol) loaded poly (lactic-co-glycolic acid) microspheres prepared by spray drying technique with lipid/cholesterol emulsifiers.
Topics: Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cholesterol; Drug Carriers; Drug Compounding; Emulsions; Lactic Acid; Lipids; Microspheres; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2001 |
Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity.
Topics: Chemical Phenomena; Chemistry, Physical; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Lactic Acid; Nanotechnology; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tumor Cells, Cultured | 2002 |
A novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitamin E TPGS.
Topics: Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Delayed-Action Preparations; Lactic Acid; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vitamin E | 2003 |
Biodegradable electrospun fibers for drug delivery.
Topics: Biodegradation, Environmental; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Drug Delivery Systems; Endopeptidase K; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Microscopy, Electron, Scanning; Nanotechnology; Paclitaxel; Polyesters; Polymers; Rifampin; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Static Electricity; Surface-Active Agents | 2003 |
In vitro hemocompatibility studies of drug-loaded poly-(L-lactic acid) fibers.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood Vessel Prosthesis; Coated Materials, Biocompatible; Curcumin; Equipment Failure Analysis; Humans; Infusion Pumps, Implantable; Lactic Acid; Materials Testing; Neutrophil Activation; Paclitaxel; Platelet Activation; Platelet Adhesiveness; Polyesters; Polymers; Stents; Surface Properties | 2003 |
PLGA/TPGS nanoparticles for controlled release of paclitaxel: effects of the emulsifier and drug loading ratio.
Topics: Delayed-Action Preparations; Drug Compounding; Emulsifying Agents; Lactic Acid; Nanotechnology; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vitamin E | 2003 |
Formulation and characterization of Paclitaxel, 5-FU and Paclitaxel + 5-FU microspheres.
Topics: Antineoplastic Agents; Breast Neoplasms; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Combinations; Female; Fluorouracil; Humans; Lactic Acid; Microspheres; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tumor Cells, Cultured | 2004 |
Molecular responses of vascular smooth muscle cells to paclitaxel-eluting bioresorbable stent materials.
Topics: Absorbable Implants; Antineoplastic Agents, Phytogenic; Antioxidants; Biocompatible Materials; Cell Adhesion; Cell Proliferation; Cells, Cultured; Extracellular Matrix; Gene Expression Profiling; Graft Occlusion, Vascular; Humans; Lactic Acid; Materials Testing; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Paclitaxel; Polyesters; Polymers; Signal Transduction; Stents | 2004 |
[Studies on paclitaxel-loaded nanoparticles of amphiphilic block copolymer].
Topics: Animals; Antineoplastic Agents, Phytogenic; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Lactic Acid; Liver Neoplasms, Experimental; Mice; Microspheres; Nanotechnology; Paclitaxel; Particle Size; Polyethylene Glycols | 2004 |
Aqueous N,N-diethylnicotinamide (DENA) solution as a medium for accelerated release study of paclitaxel.
Topics: Animals; Drug Carriers; Drug Stability; Glycolates; Kinetics; Lactic Acid; Nikethamide; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum; Solubility; Solutions | 2004 |
Paclitaxel loaded poly(L-lactic acid) (PLLA) microspheres. II. The effect of processing parameters on microsphere morphology and drug release kinetics.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Carriers; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Paclitaxel; Polyesters; Polymers; Technology, Pharmaceutical | 2004 |
Paclitaxel-loaded poly(L-lactic acid) microspheres 3: blending low and high molecular weight polymers to control morphology and drug release.
Topics: Algorithms; Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Excipients; Injections, Intraperitoneal; Lactic Acid; Microspheres; Molecular Weight; Paclitaxel; Particle Size; Polyesters; Polymers; Spectrophotometry, Ultraviolet | 2004 |
Characterization of perivascular poly(lactic-co-glycolic acid) films containing paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biodegradation, Environmental; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Delivery Systems; Lactic Acid; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar | 2004 |
Controlled release of paclitaxel from microemulsion containing PLGA and evaluation of anti-tumor activity in vitro and in vivo.
Topics: Animals; Cell Death; Cell Line, Tumor; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drug Synergism; Emulsions; Female; Humans; Lactic Acid; Mice; Mice, Nude; Microchemistry; Microscopy, Electron, Transmission; Molecular Weight; Nanotechnology; Ovarian Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Technology, Pharmaceutical; Treatment Outcome | 2004 |
Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Compounding; Drug Stability; Lactic Acid; Mice; Micelles; Paclitaxel; Particle Size; Polyethylene Glycols; Polymethacrylic Acids; Solubility; Temperature | 2005 |
Hydrophilized poly(lactide-co-glycolide) nanospheres with poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer.
Topics: Antineoplastic Agents; Biodegradation, Environmental; Drug Carriers; Drug Compounding; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Microscopy, Electron, Transmission; Nanostructures; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2004 |
Poly(d,l-lactide-co-glycolide)/montmorillonite nanoparticles for oral delivery of anticancer drugs.
Topics: Administration, Oral; Antineoplastic Agents; Bentonite; Biocompatible Materials; Caco-2 Cells; Coumarins; Drug Carriers; Drug Delivery Systems; Fluorescent Dyes; Gastrointestinal Tract; HT29 Cells; Humans; In Vitro Techniques; Lactic Acid; Microscopy, Atomic Force; Microscopy, Confocal; Nanotechnology; Paclitaxel; Particle Size; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Solvents; Temperature; Time Factors; X-Ray Diffraction | 2005 |
Effect of particle size of nanospheres and microspheres on the cellular-association and cytotoxicity of paclitaxel in 4T1 cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Boron Compounds; Brain; Cattle; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Cyclosporine; Deoxyglucose; Drug Screening Assays, Antitumor; Endocytosis; Endothelium, Vascular; Etoposide; Lactic Acid; Microspheres; Nanotubes; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2005 |
Nanoparticles of poly(lactide)/vitamin E TPGS copolymer for cancer chemotherapy: synthesis, formulation, characterization and in vitro drug release.
Topics: Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Therapy; Humans; Lactic Acid; Molecular Structure; Molecular Weight; Nanostructures; Neoplasms; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Surface Properties; Vitamin E | 2006 |
Preparation and in vitro anticancer activity of wheat germ agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and isopropyl myristate.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Kinetics; Lactic Acid; Myristates; Nanostructures; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Wheat Germ Agglutinins | 2005 |
Self-assembled biodegradable nanoparticles developed by direct dialysis for the delivery of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Dialysis; Drug Compounding; Drug Delivery Systems; Electrochemistry; Excipients; Glioma; Humans; Injections; Injections, Intravenous; Lactic Acid; Microscopy, Electron, Scanning; Nanostructures; Paclitaxel; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2005 |
In vitro and in vivo studies on vitamin E TPGS-emulsified poly(D,L-lactic-co-glycolic acid) nanoparticles for paclitaxel formulation.
Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Drug Carriers; Drug Delivery Systems; Emulsifying Agents; Glycerol; Humans; Lactic Acid; Nanostructures; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface-Active Agents; Vitamin E | 2006 |
Paclitaxel releasing films consisting of poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) and their potential as biodegradable stent coatings.
Topics: Antineoplastic Agents, Phytogenic; Biocompatible Materials; Biodegradation, Environmental; Drug Carriers; Lactic Acid; Microscopy, Electron, Scanning; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Stents; Technology, Pharmaceutical; Time Factors; X-Ray Diffraction | 2006 |
Paclitaxel-loaded microparticles and implants for the treatment of brain cancer: preparation and physicochemical characterization.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Drug Carriers; Drug Compounding; Drug Implants; Kinetics; Lactic Acid; Microspheres; Nikethamide; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Technology, Pharmaceutical; Triglycerides | 2006 |
A novel paclitaxel-eluting porous carbon-carbon nanoparticle coated, nonpolymeric cobalt-chromium stent: evaluation in a porcine model.
Topics: Analysis of Variance; Animals; Carbon; Chromium; Coated Materials, Biocompatible; Cobalt; Coronary Angiography; Coronary Restenosis; Coronary Stenosis; Coronary Vessels; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Lactic Acid; Nanostructures; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Stents; Swine | 2006 |
Susceptibility of nanoparticle-encapsulated paclitaxel to P-glycoprotein-mediated drug efflux.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Time Factors; Verapamil | 2006 |
Electrospun micro- and nanofibers for sustained delivery of paclitaxel to treat C6 glioma in vitro.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Gel; Delayed-Action Preparations; Drug Compounding; Excipients; Glioma; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Spectrometry, X-Ray Emission | 2006 |
Thermally sensitive micelles self-assembled from poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide)-b-poly(D,L-lactide-co-glycolide) for controlled delivery of paclitaxel.
Topics: Acrylamides; Acrylic Resins; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Dose-Response Relationship, Drug; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Micelles; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Temperature | 2005 |
Microencapsulation of drugs by electro-hydro-dynamic atomization.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Budesonide; Drug Compounding; Electrochemistry; Glucocorticoids; Indicators and Reagents; Lactic Acid; Paclitaxel; Particle Size; Polyesters; Polymers; Solubility; Solvents | 2006 |
Paclitaxel-loaded composite fibers: microstructure and emulsion stability.
Topics: Biocompatible Materials; Delayed-Action Preparations; Drug Delivery Systems; Drug Stability; Emulsions; Humans; In Vitro Techniques; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties; Thermodynamics | 2007 |
The effect of paclitaxel-loaded nanoparticles with radiation on hypoxic MCF-7 cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Delayed-Action Preparations; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2007 |
Poly(vinyl alcohol)-graft-poly(lactide-co-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment.
Topics: Animals; Cells, Cultured; Constriction, Pathologic; Drug Delivery Systems; Graft Occlusion, Vascular; Iliac Artery; Lactic Acid; Male; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits | 2007 |
Intratumoral delivery of paclitaxel-loaded poly(lactic-co-glycolic acid) microspheres for Hep-2 laryngeal squamous cell carcinoma xenografts.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Capillaries; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Fibroblast Growth Factor 2; Immunohistochemistry; Lactic Acid; Laryngeal Neoplasms; Mice; Microspheres; Neoplasm Transplantation; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Transplantation, Heterologous; Vascular Endothelial Growth Factor A | 2007 |
Ionically fixed polymeric nanoparticles as a novel drug carrier.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Calcium Chloride; Drug Carriers; Drug Stability; Glycerol; Injections, Intravenous; Lactic Acid; Molecular Weight; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Rats; Rats, Sprague-Dawley; Spectrophotometry; Static Electricity | 2007 |
A novel trans-lymphatic drug delivery system: implantable gelatin sponge impregnated with PLGA-paclitaxel microspheres.
Topics: Absorbable Implants; Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Drug Delivery Systems; Female; Gelatin; Lactic Acid; Lymphatic Vessels; Male; Microspheres; Molecular Weight; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity; Powders; Rats; Rats, Nude; Rats, Sprague-Dawley | 2007 |
Radiosensitization of paclitaxel, etanidazole and paclitaxel+etanidazole nanoparticles on hypoxic human tumor cells in vitro.
Topics: Antineoplastic Agents, Phytogenic; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Radiation; Etanidazole; HeLa Cells; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2007 |
[Surface-modified paclitaxel-loaded nanoparticles as local delivery system for the prevention of vessel restenosis].
Topics: Animals; Antineoplastic Agents, Phytogenic; Carotid Artery Injuries; Catheterization; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Female; Hyperplasia; Lactic Acid; Male; Nanoparticles; Nanotechnology; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Tunica Intima | 2007 |
The characterization of paclitaxel-loaded microspheres manufactured from blends of poly(lactic-co-glycolic acid) (PLGA) and low molecular weight diblock copolymers.
Topics: Antineoplastic Agents, Phytogenic; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Differential Thermal Analysis; Drug Compounding; Excipients; Lactic Acid; Luminescence; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Neutrophils; Paclitaxel; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties | 2007 |
Poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles prepared by high pressure homogenization for paclitaxel chemotherapy.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, High Pressure Liquid; Coumarins; Drug Compounding; Fluorescent Dyes; Glioma; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pressure; Tetrazolium Salts; Thiazoles | 2007 |
The preparation and characterization of anti-VEGFR2 conjugated, paclitaxel-loaded PLLA or PLGA microspheres for the systemic targeting of human prostate tumors.
Topics: Animals; Antibodies, Blocking; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Compounding; Drug Delivery Systems; Endothelial Cells; Fluorescein-5-isothiocyanate; Humans; Immunoglobulin G; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Microspheres; Neoplasm Transplantation; Paclitaxel; Particle Size; Pilot Projects; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prostatic Neoplasms; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
Preparation and Characterization of Paclitaxel-loaded PLGA nanoparticles coated with cationic SM5-1 single-chain antibody.
Topics: Antibodies, Monoclonal; Binding, Competitive; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genetic Vectors; Humans; Lactic Acid; Microscopy, Confocal; Models, Genetic; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2007 |
Multifunctional poly(D,L-lactide-co-glycolide)/montmorillonite (PLGA/MMT) nanoparticles decorated by Trastuzumab for targeted chemotherapy of breast cancer.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bentonite; Breast Neoplasms; Cell Line, Tumor; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Receptor, ErbB-2; Surface Properties; Temperature; Trastuzumab | 2008 |
Supercritical antisolvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Delayed-Action Preparations; Diffusion; Lactic Acid; Microscopy, Electron, Scanning; Models, Chemical; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polymers; Solubility; Ultrasonics | 2008 |
Paclitaxel release from single and double-layered poly(DL-lactide-co-glycolide)/poly(L-lactide) film for biodegradable coronary stent application.
Topics: Absorbable Implants; Coated Materials, Biocompatible; Diffusion; Drug Carriers; Drug-Eluting Stents; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Molecular Weight; Paclitaxel; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; Time Factors | 2008 |
Paclitaxel-loaded poly(D,L-lactide-co-glycolide) nanoparticles for radiotherapy in hypoxic human tumor cells in vitro.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Survival; Coculture Techniques; Drug Delivery Systems; HeLa Cells; Humans; Hypoxia; Kinetics; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Radiotherapy; Solvents | 2008 |
Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imaging.
Topics: Caproates; Cell Membrane; Endocytosis; Fluorescence Resonance Energy Transfer; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Lactones; Micelles; Microscopy, Fluorescence; Molecular Probes; Paclitaxel; Polyethylene Glycols; Polymers | 2008 |
Characterization and biological evaluation of paclitaxel-loaded poly(L-lactic acid) microparticles prepared by supercritical CO2.
Topics: Calorimetry, Differential Scanning; Capsules; Carbon Dioxide; Cell Line, Tumor; Cell Survival; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Paclitaxel; Particle Size; Polyesters; Polymers; X-Ray Diffraction | 2008 |
Paclitaxel-loaded microparticles for intratumoral administration via the TMT technique: preparation, characterization, and preliminary antitumoral evaluation.
Topics: Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Female; Ferrosoferric Oxide; HeLa Cells; Humans; Inhibitory Concentration 50; Lactic Acid; Magnetic Resonance Imaging; Microscopy, Electron, Scanning; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Uterine Cervical Neoplasms; X-Ray Diffraction | 2008 |
Paclitaxel loading in PLGA nanospheres affected the in vitro drug cell accumulation and antiproliferative activity.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Colloids; Coumarins; Drug Carriers; Hematologic Neoplasms; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Thiazoles | 2009 |
Slow-releasing paclitaxel in polytetrafluoroethylene/polylactide-co-glycolide laminate delays adjustment after strabismus surgery in rabbit model.
Topics: Animals; Delayed-Action Preparations; Drug Delivery Systems; Lactic Acid; Oculomotor Muscles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polytetrafluoroethylene; Postoperative Complications; Prospective Studies; Rabbits; Strabismus; Suture Techniques; Tissue Adhesions; Tubulin Modulators; Vision, Binocular | 2008 |
The intracellular uptake ability of chitosan-coated Poly (D,L-lactide-co-glycolide) nanoparticles.
Topics: Adhesives; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Electrochemistry; Excipients; Humans; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Drug Carriers; Drug Evaluation, Preclinical; Ethylene Oxide; Excipients; Flow Cytometry; Glycerol; HeLa Cells; Humans; Lactic Acid; Lactones; Male; Mice; Mice, Inbred Strains; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Survival Analysis | 2009 |
Ultrafine PEG-PLA fibers loaded with both paclitaxel and doxorubicin hydrochloride and their in vitro cytotoxicity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Chemistry, Pharmaceutical; Doxorubicin; Drug Delivery Systems; Flow Cytometry; Humans; In Vitro Techniques; Lactic Acid; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Rats; Technology, Pharmaceutical; Tetrazolium Salts; Thiazoles | 2009 |
Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Microscopy, Confocal; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Thiazoles; Xenograft Model Antitumor Assays | 2009 |
Translymphatic chemotherapy by intrapleural placement of gelatin sponge containing biodegradable Paclitaxel colloids controls lymphatic metastasis in lung cancer.
Topics: Absorption; Animals; Antineoplastic Agents, Phytogenic; Colloids; Delayed-Action Preparations; Female; Gelatin Sponge, Absorbable; Humans; Lactic Acid; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2009 |
Paclitaxel delivery from PLGA foams for controlled release in post-surgical chemotherapy against glioblastoma multiforme.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Division; Cell Line, Tumor; Chemotherapy, Adjuvant; Delayed-Action Preparations; Drug Evaluation, Preclinical; Drug Implants; Glioblastoma; Lactic Acid; Mice; Mice, Inbred BALB C; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats; Rats, Wistar; Tissue Distribution | 2009 |
Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Combinations; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Leukemia, T-Cell; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolines | 2009 |
Controlled release of paclitaxel from heparinized metal stent fabricated by layer-by-layer assembly of polylysine and hyaluronic acid-g-poly(lactic-co-glycolic acid) micelles encapsulating paclitaxel.
Topics: Dopamine; Heparin; Hyaluronic Acid; Lactic Acid; Micelles; Microscopy, Electron, Scanning; Molecular Structure; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polylysine; Stents | 2009 |
Cytotoxicity of paclitaxel incorporated in PLGA nanoparticles on hypoxic human tumor cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma; Cell Hypoxia; Cell Survival; Drug Carriers; Female; HeLa Cells; Humans; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Uterine Cervical Neoplasms | 2009 |
Evaluation of a novel slow-release paclitaxel-eluting stent with a bioabsorbable polymeric surface coating.
Topics: Animals; Antineoplastic Agents, Phytogenic; Coated Materials, Biocompatible; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug-Eluting Stents; Lactic Acid; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis Design; Swine | 2008 |
Poly(D,L-lactide-co-glycolide) nanoparticles encapsulated fluorescent isothiocyanate and paclitaxol: preparation, release kinetics and anticancer effect.
Topics: Antineoplastic Agents; Cell Survival; Delayed-Action Preparations; Diffusion; Drug Compounding; HeLa Cells; Humans; Isothiocyanates; Lactic Acid; Materials Testing; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence | 2009 |
[Controlled release of paclitaxel from microparticles containing PLLA and its anti-tumor activity on human ovarian carcinoma cell line].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Delayed-Action Preparations; Female; Humans; Lactic Acid; Ovarian Neoplasms; Paclitaxel; Particle Size; Polyesters; Polymers | 2009 |
Fabrication of biodegradable spheroidal microparticles for drug delivery applications.
Topics: Antineoplastic Agents, Phytogenic; Drug Delivery Systems; Emulsions; Glycolates; Hydrogen-Ion Concentration; Lactic Acid; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Surface Properties; Viscosity | 2009 |
Paclitaxel-loaded PLGA nanoparticles surface modified with transferrin and Pluronic((R))P85, an in vitro cell line and in vivo biodistribution studies on rat model.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioma; Lactic Acid; Male; Nanoparticles; Paclitaxel; Poloxalene; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Tissue Distribution; Transferrin | 2009 |
Hydrogel matrix entrapping PLGA-paclitaxel microspheres: drug delivery with near zero-order release and implantability advantages for malignant brain tumour chemotherapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Hydrogels; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2009 |
Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells.
Topics: Adenosine Triphosphate; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Catalase; DNA, Mitochondrial; Doxorubicin; Enzyme Inhibitors; fas Receptor; Female; Glutathione Peroxidase; Humans; L-Lactate Dehydrogenase; Lactic Acid; Mitochondria; Oxidative Stress; Oxygen Consumption; Paclitaxel; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Superoxide Dismutase; Tumor Cells, Cultured; Vincristine | 2009 |
In-vitro evaluation of paclitaxel-loaded MPEG-PLGA nanoparticles on laryngeal cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Screening Assays, Antitumor; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2009 |
Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Transport; Cells, Cultured; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Endothelial Cells; Ethylene Glycols; Humans; Integrin alphaVbeta3; Lactic Acid; Liver Neoplasms; Male; Mice; Microscopy, Fluorescence; Nanoparticles; Oligopeptides; Paclitaxel; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2009 |
[Preparation and drug release property of paclitaxel nanoparticles].
Topics: Antineoplastic Agents, Phytogenic; Chitosan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polymers | 2009 |
Peptide-conjugated biodegradable nanoparticles as a carrier to target paclitaxel to tumor neovasculature.
Topics: Aldehydes; Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Cell Movement; Cells, Cultured; Drug Carriers; Drug Delivery Systems; Female; Humans; Lactic Acid; Mice; Mice, Inbred BALB C; Molecular Structure; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Particle Size; Peptides; Polyesters; Polyethylene Glycols; Polymers | 2010 |
Nanoparticles of lipid monolayer shell and biodegradable polymer core for controlled release of paclitaxel: effects of surfactants on particles size, characteristics and in vitro performance.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Female; Humans; Inhibitory Concentration 50; Kinetics; Lactic Acid; Light; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Phosphatidylglycerols; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Scattering, Radiation; Solubility; Surface Properties; Surface-Active Agents; Technology, Pharmaceutical | 2010 |
Chitosan film containing poly(D,L-lactic-co-glycolic acid) nanoparticles: a platform for localized dual-drug release.
Topics: Chitosan; Drug Compounding; Drug Delivery Systems; Drug Stability; Fluoresceins; Gold; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2010 |
Application of rotatable central composite design in the preparation and optimization of poly(lactic-co-glycolic acid) nanoparticles for controlled delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Delayed-Action Preparations; Drug Carriers; Emulsions; Intestinal Absorption; Lactic Acid; Male; Models, Theoretical; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Solvents; Triglycerides; Ultrasonics | 2010 |
Enhanced oral bioavailability of paclitaxel formulated in vitamin E-TPGS emulsified nanoparticles of biodegradable polymers: in vitro and in vivo studies.
Topics: Absorbable Implants; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Electrochemistry; Excipients; Humans; Lactic Acid; Light; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Scattering, Radiation; Vitamin E | 2010 |
Nanoparticulate formulations for paclitaxel delivery across MDCK cell monolayer.
Topics: Animals; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Survival; Chemistry, Pharmaceutical; Dogs; Drug Delivery Systems; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Composite fiber structures with antiproliferative agents exhibit advantageous drug delivery and cell growth inhibition in vitro.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Delivery Systems; Drug-Eluting Stents; Enzyme Inhibitors; Farnesol; Humans; Kinetics; Lactic Acid; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; ras Proteins; Rats; Salicylates; Solubility | 2011 |
Active targeting behaviors of biotinylated pluronic/poly(lactic acid) nanoparticles in vitro through three-step biotin-avidin interaction.
Topics: Avidin; Biological Transport; Biotin; CA-125 Antigen; Cell Line, Tumor; Drug Delivery Systems; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Poloxalene; Polyesters; Polymers; Protein Binding | 2011 |
Fluorescent, superparamagnetic nanospheres for drug storage, targeting, and imaging: a multifunctional nanocarrier system for cancer diagnosis and treatment.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Carriers; Fluorescent Dyes; Humans; Lactic Acid; Magnetite Nanoparticles; Male; Mice; Molecular Imaging; Nanomedicine; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostatic Neoplasms; Quantum Dots | 2010 |
Core/shell microspheres via coaxial electrohydrodynamic atomization for sequential and parallel release of drugs.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Cell Line; Drug Carriers; Drug Compounding; Drug Delivery Systems; Electrochemical Techniques; Lactic Acid; Materials Testing; Microspheres; Paclitaxel; Pharmaceutical Preparations; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Suramin | 2010 |
Wheat germ agglutinin-conjugated PLGA nanoparticles for enhanced intracellular delivery of paclitaxel to colon cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Colonic Neoplasms; Drug Delivery Systems; Drug Screening Assays, Antitumor; Endocytosis; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Wheat Germ Agglutinins | 2010 |
Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and myc activity downstream of platelet-derived growth factor receptor.
Topics: Animals; Benzamides; Capillary Permeability; Carbon Isotopes; Humans; Hypoxia-Inducible Factor 1; Imatinib Mesylate; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Paclitaxel; Piperazines; Prostatic Neoplasms; Proto-Oncogene Proteins c-myc; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Vascular Endothelial Growth Factor A | 2010 |
Controllable biodegradability, drug release behavior and hemocompatibility of PTX-eluting magnesium stents.
Topics: Biodegradation, Environmental; Calorimetry, Differential Scanning; Coated Materials, Biocompatible; Drug-Eluting Stents; Humans; Lactic Acid; Magnesium; Materials Testing; Microscopy, Electron, Scanning; Molecular Weight; Paclitaxel; Platelet Adhesiveness; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2011 |
Paclitaxel/sirolimus combination coated drug-eluting stent: in vitro and in vivo drug release studies.
Topics: Animals; Antineoplastic Agents; Aorta, Abdominal; Calcium Phosphates; Coronary Artery Disease; Coronary Restenosis; Drug Combinations; Drug-Eluting Stents; Kinetics; Lactic Acid; Male; Microscopy, Electron, Scanning; Paclitaxel; Pilot Projects; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Sirolimus; Solubility; Surface Properties; Tubulin Modulators | 2011 |
Evaluation of two polymeric blends (EVA/PLA and EVA/PEG) as coating film materials for paclitaxel-eluting stent application.
Topics: Antineoplastic Agents, Phytogenic; Chromatography, Gel; Chromatography, High Pressure Liquid; Coated Materials, Biocompatible; Drug Carriers; Drug Delivery Systems; Drug-Eluting Stents; Lactic Acid; Lipid Bilayers; Microscopy, Electron, Scanning; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Stress, Mechanical; X-Ray Diffraction | 2011 |
The effect of polyethylene glycol structure on paclitaxel drug release and mechanical properties of PLGA thin films.
Topics: Drug Delivery Systems; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Mechanical Phenomena; Microscopy, Electron, Scanning; Molecular Weight; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrum Analysis, Raman; Surface Properties; Water | 2011 |
Enhanced cellular association of paclitaxel delivered in chitosan-PLGA particles.
Topics: Adhesiveness; Animals; Antineoplastic Agents, Phytogenic; Boron Compounds; Cell Line, Tumor; Chitosan; Drug Carriers; Female; Inhibitory Concentration 50; Lactic Acid; Mammary Neoplasms, Animal; Mice; Microscopy, Confocal; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2011 |
Sustained targeting of Bcr-Abl + leukemia cells by synergistic action of dual drug loaded nanoparticles and its implication for leukemia therapy.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Synergism; Humans; Lactic Acid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potential, Mitochondrial; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymerase Chain Reaction; Sirolimus | 2011 |
High-throughput screening of PLGA thin films utilizing hydrophobic fluorescent dyes for hydrophobic drug compounds.
Topics: Cardiovascular Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coated Materials, Biocompatible; Coumarins; Delayed-Action Preparations; Drug Carriers; Fluoresceins; Fluorescent Dyes; High-Throughput Screening Assays; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy; Microscopy, Electron, Scanning; Molecular Structure; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Solubility; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Surface Properties; Technology, Pharmaceutical; Thiazoles | 2011 |
A 3-in-1 polymeric micelle nanocontainer for poorly water-soluble drugs.
Topics: Benzoquinones; Cell Line, Tumor; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lactic Acid; Micelles; Models, Theoretical; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Sirolimus; Solubility; TOR Serine-Threonine Kinases; Water | 2011 |
Improved therapeutic effect of folate-decorated PLGA-PEG nanoparticles for endometrial carcinoma.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Endometrial Neoplasms; Female; Folic Acid; Humans; Lactic Acid; Mice; Mice, Nude; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Transplantation, Heterologous | 2011 |
Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery.
Topics: Animals; Aptamers, Nucleotide; Cell Proliferation; Drug Delivery Systems; Electrophoresis, Polyacrylamide Gel; Glioma; Humans; Inhibitory Concentration 50; Injections, Intravenous; Kaplan-Meier Estimate; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Nude; Nanoparticles; Oligodeoxyribonucleotides; Paclitaxel; Particle Size; Photoelectron Spectroscopy; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Static Electricity; Surface Properties; Tissue Distribution; Treatment Outcome | 2011 |
The intracellular uptake of CD95 modified paclitaxel-loaded poly(lactic-co-glycolic acid) microparticles.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Carriers; fas Receptor; Flow Cytometry; Humans; Lactic Acid; Microspheres; Paclitaxel; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2011 |
A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles.
Topics: Antineoplastic Agents, Phytogenic; Cervix Mucus; Chemistry, Pharmaceutical; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Vitamin E | 2012 |
Long circulating chitosan/PEG blended PLGA nanoparticle for tumor drug delivery.
Topics: Adsorption; Animals; Antineoplastic Agents; Biological Transport; Capsules; Cattle; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Stability; Female; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macrophages; Mice; Molecular Weight; Nanoparticles; Paclitaxel; Phagocytosis; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine | 2011 |
Enhanced in vitro antiproliferative effects of EpCAM antibody-functionalized paclitaxel-loaded PLGA nanoparticles in retinoblastoma cells.
Topics: Antibodies; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Adhesion Molecules; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cross-Linking Reagents; Drug Carriers; Endocytosis; Epithelial Cell Adhesion Molecule; Flow Cytometry; Humans; Immunoconjugates; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Poly(ADP-ribose) Polymerases; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Retinal Neoplasms; Retinoblastoma | 2011 |
Composite micelles consisting of paclitaxel- and folic acid-carrying copolymers for treatment of Lewis lung cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Lewis Lung; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Female; Folic Acid; Injections, Intravenous; Kinetics; Lactic Acid; Light; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Micelles; Microscopy, Electron, Transmission; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Polypropylenes; Scattering, Radiation; Solubility; Technology, Pharmaceutical | 2011 |
Hollow poly(MPC-g-PEG-b-PLA) graft copolymer microcapsule as a potential drug carrier.
Topics: Adsorption; Animals; Antineoplastic Agents; Biocompatible Materials; Biomimetics; Capsules; Cattle; Drug Carriers; Drug Delivery Systems; Electron Probe Microanalysis; Humans; Lactic Acid; Methacrylates; Paclitaxel; Phosphorylcholine; Polyesters; Polyethylene Glycols; Polymers; Polymethacrylic Acids; Serum Albumin, Bovine | 2012 |
One-step fabrication of polymeric Janus nanoparticles for drug delivery.
Topics: Doxorubicin; Drug Delivery Systems; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Nanoparticles; Nanotechnology; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2012 |
Pharmacokinetics and biodistribution of paclitaxel-loaded microspheres.
Topics: Algorithms; Animals; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Drug Stability; Emulsions; Lactic Acid; Microscopy, Electron, Transmission; Microspheres; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Solubility; Solvents; Tissue Distribution | 2012 |
Fabrication of drug-loaded polymer microparticles with arbitrary geometries using a piezoelectric inkjet printing system.
Topics: Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Colorimetry; Drug Delivery Systems; Excipients; HeLa Cells; Humans; Ink; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Viscosity | 2012 |
Paclitaxel loaded folic acid targeted nanoparticles of mixed lipid-shell and polymer-core: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Compounding; Drug Delivery Systems; Female; Folic Acid; HeLa Cells; Humans; Lactic Acid; Lipids; Mice; Mice, SCID; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tissue Distribution | 2012 |
Cytotoxic effect of paclitaxel incorporated in nanoparticles based on lactic and glycolic acid copolymer.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Delayed-Action Preparations; Drinking Behavior; Drug Delivery Systems; Glycolates; Humans; Jurkat Cells; Lactic Acid; Nanoparticles; Paclitaxel; Polymers; Polysorbates | 2011 |
Low molecular-weight chitosan as a pH-sensitive stealth coating for tumor-specific drug delivery.
Topics: Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Microscopy, Confocal; Molecular Structure; Molecular Weight; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
Beyond the imaging: limitations of cellular uptake study in the evaluation of nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Cell-Penetrating Peptides; Diagnostic Imaging; Drug Carriers; Drug Resistance, Multiple; Gene Products, tat; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
Poly(ethylene carbonate) nanoparticles as carrier system for chemotherapy showing prolonged in vivo circulation and anti-tumor efficacy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carbon Radioisotopes; Drug Carriers; Drug Compounding; Drug Stability; Humans; Lactic Acid; Melanoma, Experimental; Mice; Mice, Nude; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Particle Size; Polyethylenes; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Tumor Burden | 2012 |
Folic acid functionalized nanoparticles for enhanced oral drug delivery.
Topics: Absorption; Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Drug Delivery Systems; Epithelial Cells; Folic Acid; Humans; Intestinal Mucosa; Intestines; Lactic Acid; Nanoparticles; Paclitaxel; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2012 |
Effects of block copolymer properties on nanocarrier protection from in vivo clearance.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Carriers; Lactic Acid; Mice; Mice, Nude; Nanostructures; Paclitaxel; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2012 |
Formulation and evaluation of paclitaxel-loaded polymeric nanoparticles composed of polyethylene glycol and polylactic acid block copolymer.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colonic Neoplasms; Drug Carriers; Lactic Acid; Liver; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Spleen | 2012 |
PLGA nanoparticles codeliver paclitaxel and Stat3 siRNA to overcome cellular resistance in lung cancer cells.
Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Lactic Acid; Lung Neoplasms; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; STAT3 Transcription Factor | 2012 |
In vitro mutagenicity and blood compatibility of paclitaxel and curcumin in poly (DL-lactide-co-glicolide) films.
Topics: Adsorption; Antineoplastic Agents, Phytogenic; Curcumin; Drug-Eluting Stents; Fibrinogen; Humans; Lactic Acid; Mutagenicity Tests; Mutagens; Paclitaxel; Platelet Activation; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Salmonella typhi; Sirolimus | 2013 |
[Effects of modification of transferrin on cytotoxicity and intracellular delivery of paclitaxel loaded PLGA nanoparticles].
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Transferrin | 2012 |
Nanoparticle mediated co-delivery of paclitaxel and a TLR-4 agonist results in tumor regression and enhanced immune response in the tumor microenvironment of a mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Cytokines; Lactic Acid; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Toll-Like Receptor 4; Tumor Burden; Tumor Microenvironment | 2013 |
Controlled preparation and antitumor efficacy of vitamin E TPGS-functionalized PLGA nanoparticles for delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemical Precipitation; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Humans; Lactic Acid; Lung Neoplasms; Mice; Mice, Nude; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Macrophage migration inhibitory factor induces contractile and mitochondria dysfunction by altering cytoskeleton network in the human heart.
Topics: AMP-Activated Protein Kinases; Colchicine; Cytoskeleton; Humans; In Vitro Techniques; Lactic Acid; Macrophage Migration-Inhibitory Factors; Mitochondria, Heart; Muscle Contraction; Myocardium; Myocytes, Cardiac; Nitrates; Nitrites; Paclitaxel; Pyrazoles; Pyrimidines; Troponin I; Tubulin Modulators; Tumor Necrosis Factor-alpha | 2013 |
Dual anticancer drug/superparamagnetic iron oxide-loaded PLGA-based nanoparticles for cancer therapy and magnetic resonance imaging.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Cell Survival; Doxorubicin; Lactic Acid; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Inbred BALB C; Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Burden | 2013 |
Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Bronchoalveolar Lavage Fluid; Carboplatin; Celecoxib; Cell Count; Collagen; Delayed-Action Preparations; Female; L-Lactate Dehydrogenase; Lactic Acid; Lung Neoplasms; Mice; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Pulmonary Fibrosis; Pyrazoles; Sulfonamides; Vascular Endothelial Growth Factor A | 2013 |
Polydopamine-based surface modification for the development of peritumorally activatable nanoparticles.
Topics: Amino Acid Sequence; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Carriers; Female; Gene Products, tat; Humans; Indoles; Lactic Acid; Matrix Metalloproteinase 2; Molecular Sequence Data; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2013 |
Development of innovative paclitaxel-loaded small PLGA nanoparticles: study of their antiproliferative activity and their molecular interactions on prostatic cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endocytosis; Humans; Lactic Acid; Male; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostatic Neoplasms; Surface Properties | 2013 |
Antibody conjugated PLGA nanoparticles for targeted delivery of paclitaxel palmitate: efficacy and biofate in a lung cancer mouse model.
Topics: Amides; Animals; Antibodies; Antibodies, Monoclonal, Humanized; Area Under Curve; Cell Line, Tumor; Cetuximab; Cysteine; Drug Delivery Systems; ErbB Receptors; Humans; Immunotherapy; Lactic Acid; Lung Neoplasms; Mice; Mice, SCID; Nanoparticles; Nanotechnology; Neoplasm Transplantation; Paclitaxel; Palmitates; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sulfhydryl Compounds; Surface Plasmon Resonance; Surface Properties | 2013 |
Preparation and drug release mechanism of CTS-TAX-NP-MSCs drug delivery system.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Movement; Chitosan; Drug Compounding; Drug Delivery Systems; Humans; Lactic Acid; Mesenchymal Stem Cells; Mice; Multidrug Resistance-Associated Proteins; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2013 |
Flash nanoprecipitation: particle structure and stability.
Topics: Hydrophobic and Hydrophilic Interactions; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2013 |
Paclitaxel-loaded polymeric microparticles: quantitative relationships between in vitro drug release rate and in vivo pharmacodynamics.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Delayed-Action Preparations; Female; Humans; Lactic Acid; Mice; Mice, Nude; Paclitaxel; Pancreatic Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2013 |
Multifunctional biodegradable polymer nanoparticles with uniform sizes: generation and in vitro anti-melanoma activity.
Topics: Biocompatible Materials; Biodegradation, Environmental; Cell Death; Cell Line, Tumor; Cell Survival; Endocytosis; Humans; Inhibitory Concentration 50; Lactic Acid; Light; Magnetic Resonance Imaging; Magnetite Nanoparticles; Melanoma; Microscopy, Fluorescence; Paclitaxel; Particle Size; Phantoms, Imaging; Polyesters; Polymers; Polyvinyl Alcohol; Quantum Dots; Scattering, Radiation | 2013 |
Synthesis, characterization, and evaluation of paclitaxel loaded in six-arm star-shaped poly(lactic-co-glycolic acid).
Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Drug Carriers; Drug Stability; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Sodium Salicylate | 2013 |
In vitro and in vivo correlation of paclitaxel-loaded polymeric microparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Delayed-Action Preparations; Female; Humans; Lactic Acid; Paclitaxel; Pancreatic Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2013 |
Microparticles produced by the hydrogel template method for sustained drug delivery.
Topics: Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Hydrogels; Lactic Acid; Methylprednisolone; Methylprednisolone Acetate; Molecular Weight; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Risperidone; Solvents; Viscosity | 2014 |
Sequentially releasing dual-drug-loaded PLGA-casein core/shell nanomedicine: design, synthesis, biocompatibility and pharmacokinetics.
Topics: Animals; Biocompatible Materials; Caseins; Catechin; Cell Death; Cell Line; Chromatography, High Pressure Liquid; Cytokines; Humans; Indocyanine Green; Inflammation; Lactic Acid; Materials Testing; Mice; Nanomedicine; Nanoparticles; Organ Specificity; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2014 |
One-step fabrication of agent-loaded biodegradable microspheroids for drug delivery and imaging applications.
Topics: Animals; Cadmium Compounds; Cattle; Drug Delivery Systems; Emulsions; Hydrogen-Ion Concentration; Lactic Acid; Molecular Imaging; Nanoparticles; Oils; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine; Sulfides; Water | 2014 |
A targeting drug delivery system for ovarian carcinoma: transferrin modified lipid coated paclitaxel-loaded nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Stability; Endocytosis; Female; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Lipids; Liposomes; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Transmission; Nanomedicine; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; Technology, Pharmaceutical; Time Factors; Transferrin; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Self-assembled hybrid nanoparticles for targeted co-delivery of two drugs into cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Nanoparticles; Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
iNGR-modified PEG-PLGA nanoparticles that recognize tumor vasculature and penetrate gliomas.
Topics: Administration, Intravenous; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Collagen; Coumarins; Drug Combinations; Endocytosis; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Kaplan-Meier Estimate; Lactic Acid; Laminin; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteoglycans; Rats; Rats, Sprague-Dawley; Spectroscopy, Near-Infrared; Thiazoles; Tissue Distribution; Treatment Outcome | 2014 |
Nanomedicine I: In vitro and in vivo evaluation of paclitaxel loaded poly-(ε-caprolactone), poly (DL-lactide-co-glycolide) and poly (DL-lactic acid) matrix nanoparticles in wistar rats.
Topics: Animals; Lactic Acid; Magnetic Resonance Spectroscopy; Nanomedicine; Nanoparticles; Paclitaxel; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2015 |
Novel biodegradable drug-eluting stent composed of poly-L-lactic acid and amorphous calcium phosphate nanoparticles demonstrates improved structural and functional performance for coronary artery disease.
Topics: Animals; Biocompatible Materials; Calcium Phosphates; Calorimetry, Differential Scanning; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Female; Lactic Acid; Male; Materials Testing; Nanoparticles; Paclitaxel; Polyesters; Polymers; Radiography; Swine; Swine, Miniature | 2014 |
Preparation and characterization of paclitaxel-loaded poly lactic acid-co-glycolic acid coating tracheal stent.
Topics: Drug-Eluting Stents; Glycolates; Humans; Lactic Acid; Paclitaxel; Polyesters; Polymers | 2014 |
Development and evaluation of paclitaxel loaded PLGA:poloxamer blend nanoparticles for cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Discovery; Drug Stability; Hemolysis; Humans; Lactic Acid; MCF-7 Cells; Nanoparticles; Paclitaxel; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Temperature | 2014 |
Cytotoxic enhancement of hexapeptide-conjugated micelles in EGFR high-expressed cancer cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Doxorubicin; Drug Carriers; ErbB Receptors; Humans; Lactic Acid; Micelles; Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
Size-controlled biodegradable nanoparticles: preparation and size-dependent cellular uptake and tumor cell growth inhibition.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Cell Division; Cell Line; Humans; Lactic Acid; Mice; Microscopy, Electron, Scanning; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
Comparison of active, passive and magnetic targeting to tumors of multifunctional paclitaxel/SPIO-loaded nanoparticles for tumor imaging and therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Delivery Systems; Ferric Compounds; Lactic Acid; Magnetic Resonance Imaging; Magnetics; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution; Xenograft Model Antitumor Assays | 2014 |
Promoting endothelial recovery and reducing neointimal hyperplasia using sequential-like release of acetylsalicylic acid and paclitaxel-loaded biodegradable stents.
Topics: Absorbable Implants; Animals; Aorta, Abdominal; Aspirin; Biocompatible Materials; Calcium-Binding Proteins; Calponins; Drug-Eluting Stents; Electrochemical Techniques; Hyperplasia; Lactic Acid; Male; Microfilament Proteins; Nanotechnology; Paclitaxel; Platelet Adhesiveness; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits | 2014 |
Dual-layer surface coating of PLGA-based nanoparticles provides slow-release drug delivery to achieve metronomic therapy in a paclitaxel-resistant murine ovarian cancer model.
Topics: Administration, Metronomic; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Mice; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2014 |
Synergistic co-delivery of doxorubicin and paclitaxel by porous PLGA microspheres for pulmonary inhalation treatment.
Topics: Administration, Inhalation; Animals; Antineoplastic Agents; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Synergism; Lactic Acid; Lung; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Random Allocation; Treatment Outcome; Xenograft Model Antitumor Assays | 2014 |
15. Vitamin E TPGS based nanoparticles of biodegradable polymers for controlled release of anticancer drugs: Original research article: a novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitami
Topics: alpha-Tocopherol; Antineoplastic Agents, Phytogenic; Delayed-Action Preparations; History, 21st Century; Lactic Acid; Nanoparticles; Paclitaxel; Polyesters; Polyethylene Glycols; Polymers; Succinates | 2014 |
A novel combined micellar system of lapatinib and Paclitaxel with enhanced antineoplastic effect against human epidermal growth factor receptor-2 positive breast tumor in vitro.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Combinations; Drug Compounding; Endocytosis; Female; Humans; Lactic Acid; Lapatinib; Micelles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Quinazolines; Receptor, ErbB-2; Solubility; Surface Properties | 2015 |
Curcumin-loaded PLGA nanoparticles conjugated with anti- P-glycoprotein antibody to overcome multidrug resistance.
Topics: Animals; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Uterine Cervical Neoplasms | 2014 |
Enhanced antitumor efficacy of vitamin E TPGS-emulsified PLGA nanoparticles for delivery of paclitaxel.
Topics: Animals; Cell Line, Tumor; Ethanol; Female; Humans; Lactic Acid; Mice; Mice, Nude; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E; Water; Xenograft Model Antitumor Assays | 2014 |
Ultrasound contrast-enhanced imaging and in vitro antitumor effect of paclitaxel-poly(lactic-co-glycolic acid)-monomethoxypoly (ethylene glycol) nanocapsules with ultrasound-targeted microbubble destruction.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Contrast Media; Drug Carriers; Drug Delivery Systems; Flow Cytometry; Humans; Lactic Acid; Mice; Microbubbles; Microscopy, Fluorescence; Nanocapsules; Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Ultrasonography | 2015 |
"Triple-punch" strategy for triple negative breast cancer therapy with minimized drug dosage and improved antitumor efficacy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Endocytosis; Female; Humans; Indocyanine Green; Inhibitor of Apoptosis Proteins; Intracellular Space; Lactic Acid; Methacrylates; Mice; Mice, Inbred BALB C; Nanomedicine; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; Survivin; Triple Negative Breast Neoplasms | 2015 |
Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy.
Topics: Albumins; Apoptosis; Aurora Kinase B; Cell Line, Tumor; Cell Movement; Cell Nucleus Shape; Cell Proliferation; Cell Shape; Cell Survival; Drug Resistance, Neoplasm; Extracellular Space; Humans; Lactic Acid; Melanoma; Mitosis; Necrosis; Neoplasm Metastasis; Organophosphates; Paclitaxel; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Quinazolines | 2015 |
High tolerated paclitaxel nano-formulation delivered by poly (lactic-co-glycolic acid)-g-dextran micelles to efficient cancer therapy.
Topics: Animals; Breast Neoplasms; Dextrans; Drug Resistance, Neoplasm; Female; Lactic Acid; MCF-7 Cells; Mice; Micelles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2015 |
Effect of paclitaxel-loaded nanoparticles on the viability of human hepatocellular carcinoma HepG2 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Hep G2 Cells; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2015 |
Adding vitamin E-TPGS to the formulation of Genexol-PM: specially mixed micelles improve drug-loading ability and cytotoxicity against multidrug-resistant tumors significantly.
Topics: Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Chemistry, Pharmaceutical; Coumarins; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Space; Lactic Acid; Micelles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Spheroids, Cellular; Thiazoles; Vitamin E | 2015 |
Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Drug Carriers; Etoposide; Humans; Lactic Acid; Nanoparticles; Osteosarcoma; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2015 |
Controlled drug release and hydrolysis mechanism of polymer-magnetic nanoparticle composite.
Topics: Delayed-Action Preparations; Hydrolysis; Lactic Acid; Magnetite Nanoparticles; Microscopy, Atomic Force; Oleic Acid; Paclitaxel; Polyesters; Polymers; Spectrum Analysis; Time Factors; Vibration; Water | 2015 |
Sequential release of epigallocatechin gallate and paclitaxel from PLGA-casein core/shell nanoparticles sensitizes drug-resistant breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caseins; Catechin; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2015 |
Improved anticancer delivery of paclitaxel by albumin surface modification of PLGA nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Half-Life; Humans; Lactic Acid; Nanoconjugates; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin | 2015 |
Poly(d,l-lactide-co-glycolide)-chitosan composite particles for the treatment of lung cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Synergism; Humans; Lactic Acid; Lung Neoplasms; Nanocomposites; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Topotecan | 2015 |
Preparation of Polymeric Prodrug Paclitaxel-Poly(lactic acid)-b-Polyisobutylene and Its Application in Coatings of a Drug Eluting Stent.
Topics: Coated Materials, Biocompatible; Delayed-Action Preparations; Diffusion; Drug Implants; Drug-Eluting Stents; Lactic Acid; Paclitaxel; Polyenes; Polyesters; Polymers; Prodrugs; Tubulin Modulators | 2015 |
Preparation and cellular targeting study of VEGF-conjugated PLGA nanoparticles.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vascular Endothelial Growth Factor A | 2015 |
TKTL1 expression in human malign and benign cell lines.
Topics: Antineoplastic Agents; Cell Line; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucose; HCT116 Cells; HEK293 Cells; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; MCF-7 Cells; Paclitaxel; Radiation Tolerance; Transketolase | 2015 |
Degree of bioresorbable vascular scaffold expansion modulates loss of essential function.
Topics: Absorbable Implants; Blood Vessel Prosthesis; Body Fluids; Computer-Aided Design; Corrosion; Diffusion; Drug Implants; Drug-Eluting Stents; Equipment Design; Equipment Failure Analysis; Lactic Acid; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Scaffolds; Vascular Grafting | 2015 |
Controlled Dual Drug Release and In Vitro Cytotoxicity of Electrospun Poly(lactic-co-glycolic acid) Nanofibers Encapsulated with Micelles.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brefeldin A; Delayed-Action Preparations; Diffusion; Electroplating; Hep G2 Cells; Humans; Lactic Acid; Micelles; Nanocapsules; Nanofibers; Neoplasms, Experimental; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rotation; Treatment Outcome | 2015 |
Delivery of doxorubicin and paclitaxel from double-layered microparticles: The effects of layer thickness and dual-drug vs. single-drug loading.
Topics: Absorption, Physicochemical; Antineoplastic Combined Chemotherapy Protocols; Capsules; Cell Survival; Delayed-Action Preparations; Diffusion; Doxorubicin; Humans; Lactic Acid; MCF-7 Cells; Paclitaxel; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2015 |
Inhalable, large porous PLGA microparticles loaded with paclitaxel: preparation, in vitro and in vivo characterization.
Topics: Administration, Inhalation; Aerosols; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Cell Line, Tumor; Cell Survival; Drug Compounding; Humans; Lactic Acid; Lung; Male; Microspheres; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats; Rats, Sprague-Dawley | 2015 |
Sequential delivery of an anticancer drug and combined immunomodulatory nanoparticles for efficient chemoimmunotherapy.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Bone Marrow Cells; Combined Modality Therapy; Cytokines; Dendritic Cells; Female; Immunotherapy; Interleukin-10; Interleukin-12; Lactic Acid; Lymph Nodes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nanoparticles; Oligodeoxyribonucleotides; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; Toll-Like Receptor 9 | 2015 |
6-Month Follow-Up of a Novel Biodegradable Drug-Eluting Stent Composed of Poly-L-Lactic Acid and Amorphous Calcium Phosphate Nanoparticles in Porcine Coronary Artery.
Topics: Absorbable Implants; Animals; Calcium Phosphates; Coronary Restenosis; Coronary Vessels; Drug Implants; Drug-Eluting Stents; Follow-Up Studies; Lactic Acid; Longitudinal Studies; Materials Testing; Nanocapsules; Paclitaxel; Polyesters; Polymers; Swine | 2015 |
Enhanced delivery of Paclitaxel using electrostatically-conjugated Herceptin-bearing PEI/PLGA nanoparticles against HER-positive breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Drug Screening Assays, Antitumor; Drug Stability; Humans; Lactic Acid; MCF-7 Cells; Nanoparticles; Paclitaxel; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Trastuzumab | 2016 |
Stepwise pH-responsive nanoparticles containing charge-reversible pullulan-based shells and poly(β-amino ester)/poly(lactic-co-glycolic acid) cores as carriers of anticancer drugs for combination therapy on hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Delayed-Action Preparations; Glucans; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen-Ion Concentration; Lactic Acid; Liver; Liver Neoplasms; Mice; Mice, Nude; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Stilbenes | 2016 |
Luteinizing hormone-releasing hormone peptide tethered nanoparticulate system for enhanced antitumoral efficacy of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast; Breast Neoplasms; Drug Carriers; Female; Gonadotropin-Releasing Hormone; Humans; Lactic Acid; MCF-7 Cells; Mice, Nude; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2016 |
CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel.
Topics: Antibodies; Antineoplastic Agents; Drug Carriers; Drug Compounding; Drug Liberation; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gene Expression; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lactic Acid; MCF-7 Cells; Molecular Targeted Therapy; Neoplastic Stem Cells; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrans | 2016 |
PLGA-based microparticles loaded with bacterial-synthesized prodigiosin for anticancer drug release: Effects of particle size on drug release kinetics and cell viability.
Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Humans; Lactic Acid; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prodigiosin; Serratia marcescens | 2016 |
PFKFB3 potentially contributes to paclitaxel resistance in breast cancer cells through TLR4 activation by stimulating lactate production.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Gene Silencing; Glycolysis; Humans; Inhibitory Concentration 50; Lactic Acid; Paclitaxel; Phosphofructokinase-2; Signal Transduction; Toll-Like Receptor 4 | 2016 |
Vitamin E-Oligo(methyl diglycol l-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Breast Neoplasms; Cell Survival; Drug Carriers; Drug Delivery Systems; Female; Glutamic Acid; Glycols; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Tumor Cells, Cultured; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
A novel paclitaxel-loaded poly(d,l-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Humans; Lactic Acid; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polysorbates; Static Electricity | 2016 |
Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Curcumin; Drug Delivery Systems; Glioma; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2016 |
Synthesis and characterization of Fe
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Carriers; Drug Liberation; Humans; Lactic Acid; Magnetite Nanoparticles; Methacrylates; Nanocomposites; Organosilicon Compounds; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
PLGA/SBA-15 mesoporous silica composite microparticles loaded with paclitaxel for local chemotherapy.
Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Emulsions; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Microspheres; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Silicon Dioxide; Solvents | 2017 |
Targeted delivery of nano-PTX to the brain tumor-associated macrophages.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cell Line, Tumor; Coculture Techniques; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Design; Glioma; Glycoproteins; Humans; Lactic Acid; Ligands; Lipids; Macrophages; Male; Mice, Inbred BALB C; Mice, SCID; Nanoparticles; Neurons; Paclitaxel; Peptide Fragments; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Time Factors; Tissue Distribution; Viral Proteins; Xenograft Model Antitumor Assays | 2017 |
Targeted delivery of paclitaxel and doxorubicin to cancer xenografts via the nanoparticle of nano-diamino-tetrac.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; Dynamic Light Scattering; Female; Humans; Lactic Acid; Mice, Nude; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Thyroxine; Xenograft Model Antitumor Assays | 2017 |
Extended pulsated drug release from PLGA-based minirods.
Topics: Antineoplastic Agents; Biocompatible Materials; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Liberation; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Neoplasms; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prodigiosin; Spectrophotometry, Ultraviolet; Temperature | 2017 |
Tumortropic adipose-derived stem cells carrying smart nanotherapeutics for targeted delivery and dual-modality therapy of orthotopic glioblastoma.
Topics: Adipocytes; Animals; Antineoplastic Agents; Biological Transport; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Dacarbazine; Drug Carriers; Drug Liberation; Glioblastoma; Humans; Lactic Acid; Magnetite Nanoparticles; Male; Mice, Inbred C57BL; Molecular Targeted Therapy; Oleic Acid; Paclitaxel; Particle Size; Permeability; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stem Cells; Surface Properties; Temozolomide; Tissue Distribution | 2017 |
Human cytotoxic T-lymphocyte membrane-camouflaged nanoparticles combined with low-dose irradiation: a new approach to enhance drug targeting in gastric cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane; Dose-Response Relationship, Radiation; Drug Delivery Systems; Humans; Immunohistochemistry; Lactic Acid; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stomach Neoplasms; T-Lymphocytes, Cytotoxic | 2017 |
Development and validation of a reversed-phase HPLC method for the quantification of paclitaxel in different PLGA nanocarriers.
Topics: Antineoplastic Agents; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Stability; HT29 Cells; Humans; Lactic Acid; Limit of Detection; MCF-7 Cells; Nanocapsules; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrophotometry, Ultraviolet | 2017 |
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Caspases; Cell Cycle; Cell Line, Tumor; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Lipids; Nanoparticles; Oligopeptides; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Reactive Oxygen Species; Rhodamine 123; Tubulin | 2017 |
Development of biodegradable PLGA nanoparticles surface engineered with hyaluronic acid for targeted delivery of paclitaxel to triple negative breast cancer cells.
Topics: Cell Line, Tumor; Drug Carriers; Humans; Hyaluronic Acid; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Triple Negative Breast Neoplasms | 2017 |
Novel Poly(Diol Sebacate)s as Additives to Modify Paclitaxel Release From Poly(Lactic-co-Glycolic Acid) Thin Films.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Decanoic Acids; Dicarboxylic Acids; Drug Carriers; Elastic Modulus; Lactic Acid; Mice; NIH 3T3 Cells; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2017 |
Coloaded Nanoparticles of Paclitaxel and Piperlongumine for Enhancing Synergistic Antitumor Activities and Reducing Toxicity.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Dioxolanes; Drug Delivery Systems; Hep G2 Cells; Humans; Lactic Acid; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Xenograft Model Antitumor Assays | 2017 |
Enhanced intracellular delivery and controlled drug release of magnetic PLGA nanoparticles modified with transferrin.
Topics: Adsorption; Aged; Antineoplastic Agents, Phytogenic; Cell Survival; Delayed-Action Preparations; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Humans; Lactic Acid; Magnetic Fields; Magnetite Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Transferrin; Tumor Cells, Cultured | 2017 |
Cotransporting Ion is a Trigger for Cellular Endocytosis of Transporter-Targeting Nanoparticles: A Case Study of High-Efficiency SLC22A5 (OCTN2)-Mediated Carnitine-Conjugated Nanoparticles for Oral Delivery of Therapeutic Drugs.
Topics: Administration, Oral; Biological Availability; Caco-2 Cells; Carnitine; Endocytosis; Humans; Intestinal Absorption; Ions; Lactic Acid; Lymphatic System; Molecular Docking Simulation; Nanoparticles; Paclitaxel; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Messenger; Sodium; Solute Carrier Family 22 Member 5 | 2017 |
The targeting properties of folate-conjugated Pluronic F127/poly (lactic-co-glycolic) nanoparticles.
Topics: Biological Transport; Cell Line, Tumor; Drug Carriers; Drug Liberation; Folic Acid; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Developing combination of artesunate with paclitaxel loaded into poly-d,l-lactic-co-glycolic acid nanoparticle for systemic delivery to exhibit synergic chemotherapeutic response.
Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid | 2017 |
Paclitaxel-loaded and A10-3.2 aptamer-targeted poly(lactide-
Topics: Animals; Antigens, Surface; Antineoplastic Agents, Phytogenic; Aptamers, Nucleotide; Cell Line, Tumor; Drug Delivery Systems; Drug Liberation; Glutamate Carboxypeptidase II; Humans; Lactic Acid; Male; Mice; Mice, Nude; Nanostructures; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostatic Neoplasms; Ultrasonography | 2017 |
Cholera Toxin Subunit B Enabled Multifunctional Glioma-Targeted Drug Delivery.
Topics: Animals; Blood-Brain Barrier; Cell Line, Tumor; Cholera Toxin; Drug Delivery Systems; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RAW 264.7 Cells; Xenograft Model Antitumor Assays | 2017 |
Nanomanufacturing through microfluidic-assisted nanoprecipitation: Advanced analytics and structure-activity relationships.
Topics: Drug Carriers; HCT116 Cells; Humans; Lactic Acid; Microfluidics; Nanoparticles; Nanotechnology; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Reproducibility of Results; Structure-Activity Relationship; Surface-Active Agents | 2017 |
Effect of Binary Organic Solvents Together with Emulsifier on Particle Size and In vitro Behavior of Paclitaxel-Encapsulated Polymeric Lipid Nanoparticles.
Topics: Acetone; Antineoplastic Agents, Phytogenic; Cell Survival; Drug Liberation; Emulsifying Agents; Humans; Lactic Acid; Lipids; MCF-7 Cells; Methanol; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents | 2018 |
Development of a novel morphological paclitaxel-loaded PLGA microspheres for effective cancer therapy: in vitro and in vivo evaluations.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Emulsions; Female; Glioma; Hep G2 Cells; Humans; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Microspheres; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Preferential hepatic uptake of paclitaxel-loaded poly-(d-l-lactide-co-glycolide) nanoparticles - A possibility for hepatic drug targeting: Pharmacokinetics and biodistribution.
Topics: Animals; Calorimetry, Differential Scanning; Cell Survival; Drug Delivery Systems; Drug Liberation; Endocytosis; Hep G2 Cells; Humans; Hydrolysis; Kinetics; Lactic Acid; Lipid Peroxidation; Liver; Male; Malondialdehyde; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Static Electricity; Tissue Distribution | 2018 |
Novel bifurcation stents coated with bioabsorbable nanofibers with extended and controlled release of rosuvastatin and paclitaxel.
Topics: Animals; Biodegradable Plastics; Delayed-Action Preparations; Drug-Eluting Stents; Lactic Acid; Materials Testing; Nanofibers; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Rosuvastatin Calcium | 2018 |
Synthesis of Phosphoester Compounds Using Lactic Acid for Encapsulation of Paclitaxel.
Topics: Biocompatible Materials; Drug Carriers; Drug Compounding; Fatty Alcohols; Humans; Lactates; Lactic Acid; Micelles; Models, Chemical; Molecular Structure; Organophosphates; Paclitaxel; Polyethylene Glycols; Proton Magnetic Resonance Spectroscopy | 2018 |
Temporary suppression the sequestrated function of host macrophages for better nanoparticles tumor delivery.
Topics: Animals; Antineoplastic Agents; Biological Availability; Clodronic Acid; Drug Carriers; Lactic Acid; Liposomes; Liver; Macrophages; Melanoma; Mice; Mice, Inbred C57BL; Nanomedicine; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution | 2018 |
Post-resection treatment of glioblastoma with an injectable nanomedicine-loaded photopolymerizable hydrogel induces long-term survival.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Drug Liberation; Female; Glioblastoma; Humans; Hydrogels; Intraoperative Period; Lactic Acid; Methacrylates; Mice; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Magnetic targeting of paclitaxel-loaded poly(lactic-
Topics: Animals; Blood-Brain Barrier; Cell Line, Tumor; Endocytosis; Female; Glioblastoma; Humans; Lactic Acid; Magnetics; Mice, Nude; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Survival Analysis; Tissue Distribution; Xenograft Model Antitumor Assays | 2018 |
Folate-receptor-targeted laser-activable poly(lactide-
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Drug Liberation; Endocytosis; Female; Folate Receptors, GPI-Anchored; Folic Acid; Human Umbilical Vein Endothelial Cells; Humans; Hyperthermia, Induced; Indocyanine Green; Lactic Acid; Lasers; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Paclitaxel; Photoacoustic Techniques; Phototherapy; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Theranostic Nanomedicine; Tissue Distribution; Ultrasonography | 2018 |
Mesenchymal stem cells loaded with paclitaxel-poly(lactic-
Topics: Adipogenesis; Animals; Antineoplastic Agents; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Movement; Drug Carriers; Drug Delivery Systems; Endocytosis; Glioma; Humans; Kinetics; Lactic Acid; Male; Mesenchymal Stem Cells; Nanoparticles; Osteogenesis; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Tissue Distribution | 2018 |
Development of Nanoparticles for Drug Delivery to Brain Tumor: The Effect of Surface Materials on Penetration Into Brain Tissue.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Glioma; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Rats; Tissue Distribution; Vitamin E | 2019 |
Cytochrome c1 as a favorable prognostic marker in estrogen receptor-positive breast carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c1; Disease-Free Survival; Estrogen Receptor alpha; Female; Glycolysis; Humans; Ki-67 Antigen; Lactic Acid; MCF-7 Cells; Middle Aged; Paclitaxel; Phenotype; Prognosis; RNA, Small Interfering; Time Factors | 2019 |
Acyl and oligo(lactic acid) prodrugs for PEG-b-PLA and PEG-b-PCL nano-assemblies for injection.
Topics: Animals; Cell Line, Tumor; Humans; Lactic Acid; Lactones; Mice; Micelles; Paclitaxel; Polyesters; Polyethylene Glycols; Prodrugs; Tissue Distribution | 2021 |
Electrospun paclitaxel delivery system based on PGCL/PLGA in local therapy combined with brachytherapy.
Topics: Animals; Brachytherapy; Lactic Acid; Mice; Paclitaxel; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2021 |
Glucose deprivation enhances resistance to paclitaxel via ELAVL2/4-mediated modification of glycolysis in ovarian cancer cells.
Topics: Antineoplastic Agents; Caspases; Cell Line, Tumor; Drug Resistance, Neoplasm; ELAV-Like Protein 2; ELAV-Like Protein 4; Female; Glucose; Glycolysis; Humans; Lactic Acid; Ovarian Neoplasms; Paclitaxel | 2022 |
Design and Invitro Characterization of Green Synthesized Magnetic Nanoparticles Conjugated with Multitargeted Poly Lactic Acid Copolymers for Co-delivery of siRNA and Paclitaxel.
Topics: Drug Carriers; Humans; Lactic Acid; Magnetite Nanoparticles; Micelles; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polyethylene Glycols; RNA, Small Interfering | 2021 |
Surface Modification of Nanoparticles Enhances Drug Delivery to the Brain and Improves Survival in a Glioblastoma Multiforme Murine Model.
Topics: Animals; Brain; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Glioblastoma; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution | 2022 |
Hybrid Cell Membrane-Functionalized Biomimetic Nanoparticles for Targeted Therapy of Osteosarcoma.
Topics: Animals; Biomimetics; Bone Neoplasms; Cell Line, Tumor; Cell Membrane; Drug Carriers; Humans; Lactic Acid; Mice; Nanoparticles; Osteosarcoma; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution | 2022 |
Preparation of size-tunable sub-200 nm PLGA-based nanoparticles with a wide size range using a microfluidic platform.
Topics: Drug Carriers; Humans; Lactic Acid; Microfluidics; Nanoparticles; Neoplasms; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2022 |
PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells.
Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Glycolysis; Humans; Lactic Acid; Ovarian Neoplasms; Paclitaxel; Phosphoglycerate Mutase; Pyruvic Acid; RNA, Small Interfering | 2022 |
Integrated multi-omics analysis reveals unique signatures of paclitaxel-loaded poly(lactide-co-glycolide) nanoparticles treatment of head and neck cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Head and Neck Neoplasms; Humans; Lactic Acid; Multiomics; Nanoparticles; Paclitaxel; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tandem Mass Spectrometry | 2023 |