Compounds > lactic acid

lactic acid and ovalbumin

lactic acid has been researched along with ovalbumin in 121 studies

Research

Studies (121)

TimeframeStudies, this research(%)All Research%
pre-19902 (1.65)18.7374
1990's22 (18.18)18.2507
2000's31 (25.62)29.6817
2010's64 (52.89)24.3611
2020's2 (1.65)2.80

Authors

AuthorsStudies
Baba, S; Itoh, H; Kunimatsu, M; Nishimura, J; Sasaki, M; Takagi, I1
Challacombe, SJ; Davis, SS; Jeffery, H; O'Hagan, DT; Rahman, D1
Davis, SS; Jeffery, H; McGee, JP; O'Hagan, DT; Roberts, MJ1
Kaltner, H; Wittmann, J1
Challacombe, SJ; Jeffery, H; Maloy, KJ; Mowat, AM; O'Hagan, DT; Rahman, D1
Donachie, AM; Maloy, KJ; Mowat, AM; O'Hagan, DT1
Goto, S; Ninomiya, A; Uchida, T; Yoshida, K1
Goto, S; Uchida, T1
Davis, SS; Jeffery, H; O'Hagan, DT1
Foster, TP; Goto, S; Uchida, T1
Coombes, AG; Davis, SS; Yeh, MK1
Ikada, Y; Inoue, Y; Nakaoka, R; Tabata, Y1
Ikada, Y; Nakaoka, R; Tabata, Y2
Coombes, AG; Davis, SS; Jenkins, PG; Lavelle, EC1
Coombes, AG; Davis, SS; Holland, J; Lavelle, EC; Rafati, H; Stolnik, S1
Coombes, AG; Davis, SS; Lavelle, EC; Takahata, H1
Kwon, G; Newman, KD; Samuel, J1
Coombes, AG; Davis, SS; Lavelle, EC; Yeh, MK2
Cao, X; Schoichet, MS1
Labib, ME; Norris, DA; Puri, N; Sinko, PJ1
Davis, SS; Delgado, A; Hartshorne, M; Lavelle, EC1
Alcock, PJ; Crowther, M; Dutta, AS; Gellert, PR; Gormley, JJ; Hassall, L; Haworth, D; Hayward, CF; Jamieson, A; Kittlety, RS; Moores, JM; Rees, A; Reilly, CF; Wood, LJ1
Cho, SW; Choi, YW; Song, SH1
Habu, S; Itoh, T; Kawasaki, H; Kita, T; Matsunaga, Y; Tabata, Y; Usui, T; Wakatsuki, Y; Yoshida, M1
Breeze, V; Gray, T; Lin, W; Parker, KG; Parker, T1
Ariyama, T; Hiroi, T; Katayama, K; Kiyono, H; Kunisawa, J; Mayumi, T; Nakagawa, S; Okudaira, A; Takahashi, I; Tsutsumi, Y1
Brewer, JM; Pollock, KG; Sun, H1
Bandou, I; Ishida, Y; Kanzato, H; Yamamoto, N1
IKAWA, M1
Adair, BM; Earley, B; Foster, CJ; Kavanagh, OV; Murray, M1
Babensee, JE; Bennewitz, NL1
Akagi, T; Akashi, M; Baba, M; Ide, K; Kaneko, T; Okamoto, M; Sato, K; Uto, T; Wang, X1
Chen, JL; Chiang, CH; Yeh, MK1
Buttafava, A; Cilurzo, F; Conti, B; Dorati, R; Faucitano, A; Genta, I; Montanari, L1
Chesko, J; Kazzaz, J; O'hagan, DT; Singh, M; Ugozzoli, M1
Juni, K; Kimura, M; Kishino, T; Morimoto, Y; Natsume, H; Ogihara, M; Seki, T; Uchida, M1
Ackerman, AL; Cody, V; Cresswell, P; Edelson, RL; Giodini, A; Hanlon, DJ; Hinson, ER; Saltzman, WM; Shen, H1
Rodgers, VG; Zhao, A1
Conti, B; Dorati, R; Genta, I; Modena, T; Patrini, M; Pavanetto, F; Perugini, P; Stella, A1
Alshamsan, A; Elamanchili, P; Hamdy, S; Molavi, O; Samuel, J; Satou, T1
Dahle, CE; Salem, AK; Weiner, GJ; Zhang, XQ1
des Rieux, A; Fiévez, V; Freichels, H; Garinot, M; Jérôme, C; Marchand-Brynaert, J; Plapied, L; Pourcelle, V; Préat, V; Schneider, YJ; Stoffelbach, F; Theate, I1
Busch, DH; Haas, T; Heit, A; Schmitz, F; Wagner, H1
Gerelchuluun, T; Han, K; Im, SA; Kim, K; Lee, CK; Lee, YH; Lee, YR; Park, JS; Song, S1
Basit, AW; McConnell, EL; Murdan, S1
Hsu, PY; Yang, YW1
Glasgow, JM; Intra, J; Mai, HQ; Salem, AK1
Espuelas, MS; Gamazo, C; Gómez, S; Irache, JM; San Román, B; Tsapis, N1
Addy, M; Barbour, ME; Hemingway, CA; Parker, DM; Shellis, RP1
Baumeister, S; Brand, VB; Dorsch, M; Duranton, C; Hedrich, HJ; Huber, SM; Kasinathan, RS; Koka, S; Lang, C; Lang, F; Lingelbach, K; Tanneur, V1
Csaba, N; Fischer, S; Gander, B; Groettrup, M; Merkle, HP; Mueller, M; Schlosser, E1
Higaki, M; Ishihara, T; Ishizaki, J; Matsuo, Y; Miyamoto, K; Yamashita, N1
Apicella, C; Bregni, C; Chiappetta, DA; Dokmetjian, J; Gentile, T; Molinari, C; Rey Roldan, E1
Babensee, JE; Norton, LW; Park, J1
Augustijns, P; Bal, S; Bouwstra, J; Broere, F; Hagenaars, N; Jiskoot, W; Kaijzel, E; Keijzer, C; Löwik, C; Mallants, R; Que, I; Slütter, B; van Eden, W1
Bai, YJ; Gao, XY; Lu, JQ; Zhang, HG1
Appleton, JA; Blum, J; Cu, Y; Kuo-Haller, P; Saltzman, WM1
Bouwstra, JA; Gander, B; Henriksen-Lacey, M; Jiskoot, W; Johansen, P; Kündig, TM; Mohanan, D; Perrie, Y; Slütter, B1
Hunter, SK; Rodgers, VG; Zhao, A1
Han, R; Xu, H; Yang, X; Zhu, J1
Asai, Y; Fukuyama, S; Inoue, H; Kubo, M; Matsumoto, K; Matsumoto, T; Matsunaga, Y; Moriwaki, A; Nakanishi, Y; Yoshida, H; Yoshimura, A1
Ahn, GW; Im, SA; Kim, K; Lee, CK; Lee, YH; Lee, YR; Yang, IH1
Grabnar, PA; Kristl, J1
Gander, B; Groettrup, M; Mueller, M; Schlosser, E1
Bernkop-Schnürch, A; Hintzen, F; Kammona, O; Karageorgiou, V; Kiparissides, C; Kotti, K; Perera, G; Sarti, F1
Haddadi, A; Hamdy, S; Lavasanifar, A; Samuel, J; Shayeganpour, A1
Bershteyn, A; Crespo, MP; Hanson, MC; Irvine, DJ; Li, AV; Moon, JJ; Suh, H1
Gander, B; Johansen, P; Kündig, TM; Mohanan, D1
De Koker, S; De Smedt, SC; De Temmerman, ML; Demeester, J; Gander, B; Grooten, J; Libert, C; Rejman, J; Vandenbroucke, RE1
Cao, QR; Chen, D; Chen, L; Cui, J; Zhu, L1
Araman, A; Birchall, JC; Broadley, KJ; Gumbleton, M; John, E; Özsoy, Y; Yildiz, A1
Brayden, DJ; Coco, R; Jérôme, C; Plapied, L; Pourcelle, V; Préat, V; Schneider, YJ1
Geary, SM; Joshi, VB; Salem, AK1
Broere, F; Jiskoot, W; Keijzer, C; Silva, AL; Spiering, R; van Eden, W; Vervelde, L1
Guo, D; Liu, G; Sun, H; Xu, F1
Bozkır, A; Devrim, B1
Al Jamal, KT; Alpar, O; Awad, G; El-Shamy, AE; Kan, PL; Mortada, N; Osman, R1
Ahsan, F; Gupta, N; Patel, B2
Brinkhoff, B; Gürlevik, E; Harty, JT; Heemcke, J; Kubicka, S; Kühnel, F; Longerich, T; Manns, MP; Ostroumov, D; Wirth, TC; Woller, N; Zender, L1
Cho, MY; Heo, MB; Lim, YT1
Lendlein, A; Mathew, S; Wischke, C1
Barry, MA; Heffernan, MJ; Keegan, BP; Tan, MT; Wang, Q1
Cruz, LJ; Kleinovink, JW; Löwik, CW; Ossendorp, F; Rosalia, RA; Rueda, F1
Ebensen, T; Guzmán, CA; Hansen, S; Lehr, CM; Mittal, A; Schulze, K; Weißmann, S1
Altreuter, DH; Browning, E; Farokhzad, OC; Ferrari, JD; Griset, AP; Johnston, L; Kishimoto, TK; Kolte, PN; LaMothe, RA; Langer, R; Maldonado, RA; O'Neil, C; Rossi, RJ; Scott, DW; von Andrian, UH; Zhang, AH1
Jiskoot, W; Ossendorp, F; Rosalia, RA; Sibuea, S; Silva, AL; Varypataki, E1
Espuelas, S; Gómez, S; Irache, JM; San Román, B1
Ebensen, T; Guzmán, CA; Hansen, S; Lehr, CM; Mittal, A; Schulze, K; Weissmann, S1
Kang-Mieler, JJ; Osswald, CR1
Chen, X; Jia, J; Liu, Q; Ma, G; Wang, L; Yang, T; Zhang, W1
Chen, X; Haddadi, A; Izadifar, M; Kelly, ME1
Chen, X; Jia, J; Liu, Q; Liu, Y; Ma, G; Wang, L; Yang, T; Zhang, W1
Bruno, C; Gander, B; Håkerud, M; Johansen, P; Kündig, TM; Waeckerle-Men, Y1
Bowden, NB; Geary, SM; Hu, Q; Joshi, VB; Salem, AK1
Bifulco, K; Buonaguro, FM; Buonaguro, L; Carriero, V; Conte, C; De Stradis, A; Napolitano, M; Petrizzo, A; Quaglia, F; Tagliamonte, M; Tornesello, ML1
Luo, WH; Yang, YW1
Czaplewska, JA; Gottschaldt, M; Lehr, CM; Majdanski, TC; Rietscher, R; Schneider, M; Schubert, US1
Kong, D; Leng, X; Liu, L; Ma, G; Ma, P; Song, C; Sun, H; Wang, C; Wang, H; Zhang, C1
Barnier-Quer, C; Collin, N; Jiskoot, W; Ossendorp, F; Silva, AL; Varypataki, EM1
Ahmed, KK; Geary, SM; Salem, AK1
Baruch, L; Bronshtein, T; Gilert, A; Machluf, M1
Chang, D; Fang, K; Gu, N; Li, MC; Shahzad, KA; Shen, CL; Wang, W; Xu, T; Zhang, L1
Czaplewska, J; Gottschaldt, M; Hanefeld, A; Janke, J; Knolle, PA; Lehr, CM; Rietscher, R; Scherließ, R; Schneider, M; Schröder, M; Schubert, US1
Lim, YT; Noh, YW; Song, C1
Cardieri, MC; Eren, M; Guldner, D; Hwang, JK; Norton, MG; Souza, CD; Ziaei, P1
Abnous, K; Ebrahimian, M; Haghparast, A; Hashemi, M; Hashemitabar, G; Maleki, M; Ramezani, M1
Alshamsan, A1
Afonso, CAM; Curato, C; Florindo, HF; Gaspar, R; Jung, S; Moreira, JN; Paisana, M; Pinto, J; Porat, Z; Rodrigues, C; Satchi-Fainaro, R; Viana, AS; Zupančič, E1
Bailey, BA; Ciotti, SM; Desai, KH; Moon, JJ; Ochyl, LJ; Schwendeman, SP1
Bo, R; Hu, Y; Huang, Y; Liu, J; Liu, Z; Luo, L; Qin, T; Wang, D; Xing, J; Zheng, S1
Bouwstra, JA; Broere, F; de Groot, AM; Du, G; Mönkäre, J; Platteel, ACM; Sijts, AJAM1
Bouwstra, JA; Du, G; Hathout, RM; Jiskoot, W; Koning, RI; Koster, AJ; Kros, A; Mönkäre, J; Nasr, M; Nejadnik, MR; Slütter, B; Tu, J1
Bodmeier, R; Duque, L; Körber, M1
Haddadi, A; Jahan, ST; Sadat, SM1
Ebensen, T; Guzmán, CA; Harms, M; Lucas, H; Mäder, K; Riehl, M1
Bouwstra, JA; Du, G; Jiskoot, W; Leone, M; Mönkäre, J; Nejadnik, MR; O'Mahony, C; Pontier, M; Romeijn, S; Slütter, B; van Kampen, EEM1
Dong, L; Liu, SF; Nie, Q; Niu, Y; Song, D; Song, W; Wang, X; Wu, G; Zhang, J1
Cao, F; Gao, W; Ge, J; Ming, Y; Ogino, K1

Other Studies

121 other study(ies) available for lactic acid and ovalbumin

ArticleYear
Poly (lactic/glycolic acid) microspheres containing antigen as a novel and potential agent of immunotherapy for allergic disorders.
    Arerugi = [Allergy], 1992, Volume: 41, Issue:9

    Topics: Animals; Antigens; Drug Delivery Systems; Guinea Pigs; Humans; Hypersensitivity; Immunoglobulin G; Immunotherapy; Injections; Lactates; Lactic Acid; Microspheres; Ovalbumin; Polyesters; Polyglycolic Acid; Polymers

1992
Enhanced secretory IgA and systemic IgG antibody responses after oral immunization with biodegradable microparticles containing antigen.
    Immunology, 1992, Volume: 76, Issue:1

    Topics: Administration, Oral; Animals; Antigens; Biodegradation, Environmental; Delayed-Action Preparations; Immunization; Immunization Schedule; Immunoglobulin A, Secretory; Immunoglobulin G; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Saliva

1992
Controlled release microparticles for vaccine development.
    Vaccine, 1991, Volume: 9, Issue:10

    Topics: Animals; Delayed-Action Preparations; Enzyme-Linked Immunosorbent Assay; Freund's Adjuvant; Immunization, Secondary; Immunoglobulin G; Injections, Subcutaneous; Lactic Acid; Male; Microspheres; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Inbred Strains; Vaccines

1991
Formation and changes of the subembryonic liquid from turned, unturned, and cultured Japanese quail eggs.
    Biotechnology and applied biochemistry, 1988, Volume: 10, Issue:4

    Topics: Animals; Coturnix; Culture Techniques; Embryo, Nonmammalian; Glucose; Lactates; Lactic Acid; Ovalbumin; Quail

1988
Biodegradable microparticles as oral vaccines.
    Advances in experimental medicine and biology, 1995, Volume: 371B

    Topics: Administration, Oral; Animals; Antigens; Biocompatible Materials; Biodegradation, Environmental; Capsules; Delayed-Action Preparations; Drug Delivery Systems; Immunity, Mucosal; Immunoglobulin A, Secretory; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Saliva; T-Lymphocytes, Cytotoxic; Vaccines

1995
Induction of mucosal and systemic immune responses by immunization with ovalbumin entrapped in poly(lactide-co-glycolide) microparticles.
    Immunology, 1994, Volume: 81, Issue:4

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Cell Division; Epitopes; Female; Hypersensitivity, Delayed; Immunization; Immunoglobulin G; Injections, Subcutaneous; ISCOMs; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; T-Lymphocytes; T-Lymphocytes, Cytotoxic

1994
Optimization of preparative conditions for polylactide (PLA) microspheres containing ovalbumin.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:9

    Topics: Biocompatible Materials; Emulsions; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility

1995
Oral delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin as vaccine formulation: particle size study.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:9

    Topics: Adjuvants, Immunologic; Animals; Enzyme-Linked Immunosorbent Assay; Female; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vaccines

1994
Long-term antibody responses in mice following subcutaneous immunization with ovalbumin entrapped in biodegradable microparticles.
    Vaccine, 1993, Volume: 11, Issue:9

    Topics: Animals; Biodegradation, Environmental; Delayed-Action Preparations; Drug Compounding; Immunity, Active; Immunoglobulin G; Injections, Subcutaneous; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

1993
Particle size studies for subcutaneous delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin as vaccine formulation.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:7

    Topics: Alum Compounds; Animals; Antibody Formation; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Female; Freund's Adjuvant; In Vitro Techniques; Injections, Subcutaneous; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vaccines, Synthetic

1995
Improving protein delivery from microparticles using blends of poly(DL lactide co-glycolide) and poly(ethylene oxide)-poly(propylene oxide) copolymers.
    Pharmaceutical research, 1996, Volume: 13, Issue:11

    Topics: Chemistry, Pharmaceutical; Drug Delivery Systems; Emulsions; Kinetics; Lactic Acid; Ovalbumin; Particle Size; Pharmaceutic Aids; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Propylene Glycols; Proteins; Solutions

1996
Size effect on the antibody production induced by biodegradable microspheres containing antigen.
    Vaccine, 1996, Volume: 14, Issue:13

    Topics: Animals; Antibody Formation; Antigens; Female; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Microspheres; Ovalbumin; Polyesters; Polymers

1996
Production of interleukin 1 from macrophages incubated with poly (DL-lactic acid) granules containing ovalbumin.
    Biomaterials, 1996, Volume: 17, Issue:23

    Topics: Animals; Cells, Cultured; Delayed-Action Preparations; Dose-Response Relationship, Immunologic; Drug Carriers; Interleukin-1; Lactic Acid; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Ovalbumin; Particle Size; Phagocytosis; Polyesters; Polymers; Powders

1996
Single dose, polymeric, microparticle-based vaccines: the influence of formulation conditions on the magnitude and duration of the immune response to a protein antigen.
    Vaccine, 1996, Volume: 14, Issue:15

    Topics: Alum Compounds; Animals; Antibodies; Biocompatible Materials; Drug Carriers; Immunoglobulin G; Lactic Acid; Mice; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vaccines

1996
Adjuvant effect of biodegradable poly(DL-lactic acid) granules capable for antigen release following intraperitoneal injection.
    Vaccine, 1996, Volume: 14, Issue:17-18

    Topics: Adjuvants, Immunologic; Animals; Antigens; Biodegradation, Environmental; Hydrogel, Polyethylene Glycol Dimethacrylate; Injections, Intraperitoneal; Lactic Acid; Mice; Ovalbumin; Polyesters; Polyethylene Glycols; Polymers; Polyvinyl Alcohol; Stereoisomerism

1996
The immune response to a model antigen associated with PLG microparticles prepared using different surfactants.
    Vaccine, 1997, Volume: 15, Issue:17-18

    Topics: Animals; Antigens; Bile Acids and Salts; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Emulsions; Female; Glycerol; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Ovalbumin; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Surface Properties; Surface-Active Agents

1997
The distribution of protein associated with poly(DL-lactide co-glycolide) microparticles and its degradation in simulated body fluids.
    Journal of controlled release : official journal of the Controlled Release Society, 1998, Jan-02, Volume: 50, Issue:1-3

    Topics: Body Fluids; Lactic Acid; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

1998
Ovalbumin peptide encapsulated in poly(d,l lactic-co-glycolic acid) microspheres is capable of inducing a T helper type 1 immune response.
    Journal of controlled release : official journal of the Controlled Release Society, 1998, Volume: 54, Issue:1

    Topics: Amino Acid Sequence; Animals; Drug Carriers; Female; Interferon-gamma; Interleukin-10; Interleukin-4; Lactic Acid; Mice; Mice, Inbred C57BL; Microspheres; Molecular Sequence Data; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Th1 Cells

1998
The control of protein release from poly(DL-lactide co-glycolide) microparticles by variation of the external aqueous phase surfactant in the water-in oil-in water method.
    Journal of controlled release : official journal of the Controlled Release Society, 1998, Mar-31, Volume: 52, Issue:3

    Topics: Drug Carriers; Lactic Acid; Microscopy, Electron, Scanning; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface-Active Agents; Water

1998
Delivering neuroactive molecules from biodegradable microspheres for application in central nervous system disorders.
    Biomaterials, 1999, Volume: 20, Issue:4

    Topics: Animals; Biodegradation, Environmental; Cell Differentiation; Central Nervous System Diseases; Drug Carriers; Lactic Acid; Microspheres; Nerve Growth Factors; Neurons; Ovalbumin; PC12 Cells; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats

1999
The stability and immunogenicity of a protein antigen encapsulated in biodegradable microparticles based on blends of lactide polymers and polyethylene glycol.
    Vaccine, 1999, Feb-12, Volume: 17, Issue:6

    Topics: Animals; Antigens; Biodegradation, Environmental; Female; Hydrogen-Ion Concentration; Immunization; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Ovalbumin; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

1999
Determining the absolute surface hydrophobicity of microparticulates using thin layer wicking.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, May-20, Volume: 59, Issue:2

    Topics: Adsorption; Biocompatible Materials; Chemistry, Pharmaceutical; Lactic Acid; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polystyrenes; Reproducibility of Results; Solubility

1999
PLG microparticles stabilised using enteric coating polymers as oral vaccine delivery systems.
    Vaccine, 1999, Jul-16, Volume: 17, Issue:22

    Topics: Administration, Oral; Animals; Biocompatible Materials; Drug Delivery Systems; Drug Stability; Female; Immunoglobulin A; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties; Vaccines

1999
Potent cyclic monomeric and dimeric peptide inhibitors of VLA-4 (alpha4beta1 integrin)-mediated cell adhesion based on the Ile-Leu-Asp-Val tetrapeptide.
    Journal of peptide science : an official publication of the European Peptide Society, 2000, Volume: 6, Issue:7

    Topics: Amino Acid Sequence; Animals; Cell Adhesion; Cell Line; CHO Cells; Cricetinae; Delayed-Action Preparations; Dimerization; Drug Stability; Humans; Hypersensitivity, Delayed; Integrin alpha4beta1; Integrins; Lactic Acid; Mice; Mice, Inbred BALB C; Ovalbumin; Peptides, Cyclic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Receptors, Lymphocyte Homing; U937 Cells

2000
Effects of solvent selection and fabrication method on the characteristics of biodegradable poly(lactide-co-glycolide) microspheres containing ovalbumin.
    Archives of pharmacal research, 2000, Volume: 23, Issue:4

    Topics: Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2000
Oral immunization with size-purified microsphere beads as a vehicle selectively induces systemic tolerance and sensitization.
    Vaccine, 2000, Oct-15, Volume: 19, Issue:4-5

    Topics: Administration, Oral; Animals; Antigens; Drug Delivery Systems; Hypersensitivity, Delayed; Immune Tolerance; Immunization; Immunoglobulin A, Secretory; Immunoglobulin G; Interferon-gamma; Interleukin-4; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microspheres; Ovalbumin; Particle Size; Peyer's Patches; Polyesters; Polymers; Receptors, Antigen, T-Cell; Spleen

2000
Lactic acid-stabilised albumin for microsphere formulation and biomedical coatings.
    Biomaterials, 2001, Volume: 22, Issue:1

    Topics: Blood Vessel Prosthesis; Coated Materials, Biocompatible; Emulsions; Lactic Acid; Microscopy, Electron; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Polyethylene Terephthalates; Soybean Oil

2001
Lack of antigen-specific immune responses in anti-IL-7 receptor alpha chain antibody-treated Peyer's patch-null mice following intestinal immunization with microencapsulated antigen.
    European journal of immunology, 2002, Volume: 32, Issue:8

    Topics: Animals; Antibodies, Monoclonal; CD4-Positive T-Lymphocytes; Dendritic Cells; Female; Immunity, Mucosal; Immunization; Immunoglobulin A; Immunoglobulin G; Intestinal Mucosa; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Microspheres; Ovalbumin; Peyer's Patches; Polyesters; Polymers; Receptors, Interleukin-7

2002
Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro.
    Vaccine, 2003, Feb-14, Volume: 21, Issue:9-10

    Topics: Adjuvants, Immunologic; Animals; Antigen Presentation; Antigens; Dendritic Cells; Hybridomas; In Vitro Techniques; Kinetics; Lactic Acid; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface-Active Agents; T-Lymphocytes; Vaccines

2003
Decrease in ovalbumin specific IgE of mice serum after oral uptake of lactic acid bacteria.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:5

    Topics: Animals; Bacterial Adhesion; Bifidobacterium; Culture Media; Digestive System; Enzyme-Linked Immunosorbent Assay; Fermentation; Immunoglobulin E; Immunoglobulin G; Lactic Acid; Lactobacillus; Lactobacillus acidophilus; Male; Mice; Mice, Inbred BALB C; Milk; Ovalbumin

2003
THE CONFIGURATION OF ASPARTIC ACID IN CELL WALLS OF LACTIC ACID BACTERIA AND FACTORS AFFECTING THE RACEMIZATION OF ASPARTIC ACID.
    Biochemistry, 1964, Volume: 3

    Topics: Aspartic Acid; Bacterial Proteins; Carboxy-Lyases; Caseins; Cell Wall; Chemical Phenomena; Chemistry; Chromatography; Electrophoresis; Hydrochloric Acid; Ion Exchange Resins; Lactic Acid; Leuconostoc; Mucoproteins; Ovalbumin; Peptides; Research

1964
Antigen-specific IgA and IgG responses in calves inoculated intranasally with ovalbumin encapsulated in poly(DL-lactide-co-glycolide) microspheres.
    Vaccine, 2003, Oct-01, Volume: 21, Issue:27-30

    Topics: Administration, Intranasal; Animals; Cattle; Drug Compounding; Immunization, Secondary; Immunoglobulin A; Immunoglobulin G; Kinetics; Lactic Acid; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins

2003
The effect of the physical form of poly(lactic-co-glycolic acid) carriers on the humoral immune response to co-delivered antigen.
    Biomaterials, 2005, Volume: 26, Issue:16

    Topics: Animals; Antigens; Biocompatible Materials; Drug Carriers; Enzyme-Linked Immunosorbent Assay; Glycolates; Immune System; Immunoglobulin G; Kinetics; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Microspheres; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; T-Lymphocytes; Th1 Cells; Th2 Cells; Time Factors; Tissue Engineering

2005
Potent activation of antigen-specific T cells by antigen-loaded nanospheres.
    Immunology letters, 2005, Apr-15, Volume: 98, Issue:1

    Topics: Animals; Antigen-Presenting Cells; Antigens; Fluorescein-5-isothiocyanate; Kinetics; Lactic Acid; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanotubes; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polystyrenes; T-Lymphocytes

2005
The mechanism of surface-indented protein-loaded PLGA microparticle formation: the effects of salt (NaCl) on the solidification process.
    Journal of microencapsulation, 2004, Volume: 21, Issue:8

    Topics: Adsorption; Drug Compounding; Drug Delivery Systems; Hydrogen-Ion Concentration; Lactic Acid; Methylene Chloride; Microspheres; Osmotic Pressure; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine; Sodium Chloride; Surface Properties

2004
The effect of gamma-irradiation on PLGA/PEG microspheres containing ovalbumin.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Sep-20, Volume: 107, Issue:1

    Topics: Excipients; Gamma Rays; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Sodium Chloride

2005
An investigation of the factors controlling the adsorption of protein antigens to anionic PLG microparticles.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:11

    Topics: Adsorption; Antigens; Carbonic Anhydrases; Drug Delivery Systems; HIV Envelope Protein gp120; Hydrogen-Ion Concentration; Lactic Acid; Microscopy, Atomic Force; Microspheres; Muramidase; Osmolar Concentration; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protein Binding; Proteins; Static Electricity; Surface Properties; Vaccines

2005
Immunization by particle bombardment of antigen-loaded poly-(DL-lactide-co-glycolide) microspheres in mice.
    Vaccine, 2006, Mar-15, Volume: 24, Issue:12

    Topics: Air Pressure; Animals; Antigens; Helium; Immunization; Lactic Acid; Mice; Mice, Inbred BALB C; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Skin

2006
Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles.
    Immunology, 2006, Volume: 117, Issue:1

    Topics: Animals; Antigen Presentation; B-Lymphocytes; Biocompatible Materials; Biodegradation, Environmental; Cell Line; Cross-Priming; Dendritic Cells; Endosomes; Histocompatibility Antigens Class II; Humans; Lactic Acid; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Nanostructures; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine; T-Lymphocytes

2006
Using TEM to couple transient protein distribution and release for PLGA microparticles for potential use as vaccine delivery vehicles.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Jun-12, Volume: 113, Issue:1

    Topics: Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Time Factors; Tissue Distribution; Vaccines

2006
Surface characterization by atomic force microscopy of sterilized PLGA microspheres.
    Journal of microencapsulation, 2006, Volume: 23, Issue:2

    Topics: Drug Carriers; Gamma Rays; Lactic Acid; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sterilization

2006
Enhanced antigen-specific primary CD4+ and CD8+ responses by codelivery of ovalbumin and toll-like receptor ligand monophosphoryl lipid A in poly(D,L-lactic-co-glycolic acid) nanoparticles.
    Journal of biomedical materials research. Part A, 2007, Jun-01, Volume: 81, Issue:3

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Clone Cells; Cytokines; Epitopes; Glycolates; Injections, Intraperitoneal; Injections, Subcutaneous; Kinetics; Lactic Acid; Lipid A; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Toll-Like Receptors; Vaccination

2007
A comparative study of the antigen-specific immune response induced by co-delivery of CpG ODN and antigen using fusion molecules or biodegradable microparticles.
    Journal of pharmaceutical sciences, 2007, Volume: 96, Issue:12

    Topics: Adjuvants, Immunologic; Alum Compounds; Animals; Cells, Cultured; Dendritic Cells; Drug Carriers; Drug Compounding; Female; Immunoconjugates; Immunoglobulin G; Interferon-gamma; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligodeoxyribonucleotides; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Receptors, Antigen, T-Cell; Technology, Pharmaceutical; Vaccines, Synthetic

2007
PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Jul-31, Volume: 120, Issue:3

    Topics: Administration, Oral; Animals; Caco-2 Cells; Cell Line, Tumor; Coculture Techniques; Epithelial Cells; Female; Fluorescein-5-isothiocyanate; Humans; Immunization, Secondary; Injections, Intramuscular; Integrin alpha5beta1; Integrin beta1; Intestinal Mucosa; Lactic Acid; Mice; Mice, Inbred Strains; Nanoparticles; Oligopeptides; Ovalbumin; Ovarian Follicle; Peyer's Patches; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vaccination

2007
Antigen co-encapsulated with adjuvants efficiently drive protective T cell immunity.
    European journal of immunology, 2007, Volume: 37, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Antigen Presentation; Antigens; Dendritic Cells; Endosomes; Lactic Acid; Lymphocyte Activation; Mice; Mice, Transgenic; Microscopy, Confocal; Microspheres; Oligodeoxyribonucleotides; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; T-Lymphocytes; Toll-Like Receptors; Vaccines, Synthetic

2007
Dendritic cells process antigens encapsulated in a biodegradable polymer, poly(D,L-lactide-co-glycolide), via an alternate class I MHC processing pathway.
    Archives of pharmacal research, 2007, Volume: 30, Issue:11

    Topics: Acetylcysteine; Antigen Presentation; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Brefeldin A; Cell Line; Chloroquine; Dendritic Cells; Histocompatibility Antigens Class I; Humans; Lactic Acid; Nanospheres; Ovalbumin; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2007
Colonic antigen administration induces significantly higher humoral levels of colonic and vaginal IgA, and serum IgG compared to oral administration.
    Vaccine, 2008, Jan-30, Volume: 26, Issue:5

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antibodies, Bacterial; Antigens; Colon; Drug Administration Routes; Drug Carriers; Female; Immunity, Mucosal; Immunoglobulin A; Immunoglobulin G; Intestinal Mucosa; Lactic Acid; Mice; Mice, Inbred BALB C; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vagina

2008
The effect of poly(D,L-lactide-co-glycolide) microparticles with polyelectrolyte self-assembled multilayer surfaces on the cross-presentation of exogenous antigens.
    Biomaterials, 2008, Volume: 29, Issue:16

    Topics: Animals; Antigen Presentation; CD8-Positive T-Lymphocytes; Cells, Cultured; Cross-Priming; Dendritic Cells; Dextran Sulfate; Hybridomas; Lactic Acid; Macrophages; Major Histocompatibility Complex; Mice; Microspheres; Ovalbumin; Phagocytosis; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Reactive Oxygen Species; Static Electricity

2008
Pulsatile release of biomolecules from polydimethylsiloxane (PDMS) chips with hydrolytically degradable seals.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, May-08, Volume: 127, Issue:3

    Topics: Cell Line; Dimethylpolysiloxanes; DNA; Humans; Hydrolysis; Lactic Acid; Oligodeoxyribonucleotides; Ovalbumin; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Silicones; Transfection

2008
Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 70, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antibodies; Antibody Formation; Antigens; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Dendritic Cells; Drug Carriers; Female; Immunity, Cellular; Injections, Intradermal; Interferon-gamma; Interleukin-4; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Technology, Pharmaceutical; Th1 Cells; Time Factors; Vaccines

2008
Inhibition of hydroxyapatite dissolution by ovalbumin as a function of pH, calcium concentration, protein concentration and acid type.
    Caries research, 2008, Volume: 42, Issue:5

    Topics: Adsorption; Calcium; Citric Acid; Durapatite; Humans; Hydrogen-Ion Concentration; Lactic Acid; Malates; Materials Testing; Ovalbumin; Protein Denaturation; Solubility; Surface Properties

2008
A high specificity and affinity interaction with serum albumin stimulates an anion conductance in malaria-infected erythrocytes.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2008, Volume: 22, Issue:5-6

    Topics: Animals; Caseins; Chloride Channels; Erythrocytes; Humans; Ion Channel Gating; Lactic Acid; Malaria; Ovalbumin; Plasmodium falciparum; Recombinant Proteins; Serum Albumin; Serum Albumin, Bovine

2008
Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response.
    Journal of drug targeting, 2009, Volume: 17, Issue:8

    Topics: Animals; Capsules; Chitosan; Female; Interferon-gamma; Lactic Acid; Ligands; Mice; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Ovalbumin; Peptide Fragments; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protamines; T-Lymphocytes, Cytotoxic; Toll-Like Receptors

2009
Effect of betamethasone phosphate loaded polymeric nanoparticles on a murine asthma model.
    Cellular immunology, 2009, Volume: 260, Issue:1

    Topics: Animals; Asthma; Betamethasone; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Delivery Systems; Female; Glucocorticoids; Interleukin-13; Interleukin-4; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; Ovalbumin; Polyesters; Polyethylene Glycols; Polymers

2009
Asymmetric IgG antibodies induced by different immunotherapies in a murine model of allergy.
    Immunological investigations, 2009, Volume: 38, Issue:7

    Topics: Animals; Cells, Cultured; Chromatography, Affinity; Desensitization, Immunologic; Disease Models, Animal; Glycolates; Hypersensitivity; Immunoglobulin E; Immunoglobulin G; Interferon-gamma; Interleukin-10; Interleukin-4; Lactic Acid; Mice; Mice, Inbred BALB C; Ovalbumin; Passive Cutaneous Anaphylaxis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spleen; Time Factors

2009
Biomaterial adjuvant effect is attenuated by anti-inflammatory drug delivery or material selection.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Sep-15, Volume: 146, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Biocompatible Materials; Dendritic Cells; Dexamethasone; Immunity, Humoral; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sepharose; Tissue Scaffolds

2010
Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.
    Vaccine, 2010, Aug-31, Volume: 28, Issue:38

    Topics: Administration, Intranasal; Animals; Antibody Formation; Cells, Cultured; Chitosan; Dendritic Cells; Drug Carriers; Female; Humans; Immunoglobulin A, Secretory; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccination

2010
A LC-MS-based method for quantification of biomarkers from serum of allergic rats.
    Molecules (Basel, Switzerland), 2010, May-07, Volume: 15, Issue:5

    Topics: Animals; Arachidonic Acid; Biomarkers; Chromatography, Liquid; Histamine; Hypersensitivity; Lactic Acid; Leukotriene B4; Mass Spectrometry; Ovalbumin; Prostaglandin D2; Rats; Sensitivity and Specificity; Valine

2010
Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Administration, Intravaginal; Administration, Oral; Animals; Antibody Specificity; Drug Delivery Systems; Female; Immunity, Mucosal; Immunization, Secondary; Immunoglobulin A; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Microspheres; Models, Immunological; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccines; Vagina

2010
Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Nov-01, Volume: 147, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Drug Administration Routes; Drug Carriers; Drug Delivery Systems; Female; Immunoglobulin G; Interferon-gamma; Kinetics; Lactic Acid; Liposomes; Mice; Mice, Inbred BALB C; Nanoparticles; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Spleen; Th1 Cells; Th2 Cells; Time Factors; Vaccines

2010
Theoretical prediction of induction period from transient pore evolvement in polyester-based microparticles.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:11

    Topics: Animals; Biocompatible Materials; Cattle; Drug Carriers; Kinetics; Lactic Acid; Models, Chemical; Ovalbumin; Pharmaceutical Preparations; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine

2010
Surface modification of poly(D,L-lactic-co-glycolic acid) nanoparticles with protamine enhanced cross-presentation of encapsulated ovalbumin by bone marrow-derived dendritic cells.
    Journal of biomedical materials research. Part A, 2011, Volume: 96, Issue:1

    Topics: Animals; Antigens; Biocompatible Materials; Bone Marrow Cells; Cross-Priming; Dendritic Cells; Drug Compounding; Lactic Acid; Male; Materials Testing; Mice; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protamines; Surface Properties

2011
Effects of a Janus kinase inhibitor, pyridone 6, on airway responses in a murine model of asthma.
    Biochemical and biophysical research communications, 2011, Jan-07, Volume: 404, Issue:1

    Topics: Animals; Asthma; Benzimidazoles; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Capsules; Chloride Channels; Eosinophilia; Interleukin-13; Janus Kinases; Lactic Acid; Lung; Mice; Mucoproteins; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Kinase Inhibitors; Pyridones; STAT6 Transcription Factor; Th2 Cells

2011
Biodegradable nanoparticles containing TLR3 or TLR9 agonists together with antigen enhance MHC-restricted presentation of the antigen.
    Archives of pharmacal research, 2010, Volume: 33, Issue:11

    Topics: Animals; Antigen Presentation; Antigens; Cell Proliferation; Dendritic Cells; Histocompatibility Antigens Class I; Immunoglobulin G; Lactic Acid; Mice; Nanoparticles; Oligodeoxyribonucleotides; Ovalbumin; Poly I-C; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Toll-Like Receptor 3; Toll-Like Receptor 9

2010
Physicochemical characterization of protein-loaded pectin-chitosan nanoparticles prepared by polyelectrolyte complexation.
    Die Pharmazie, 2010, Volume: 65, Issue:11

    Topics: Chitosan; Chromatography, High Pressure Liquid; Electrochemistry; Electrolytes; Excipients; Lactic Acid; Nanoparticles; Ovalbumin; Pectins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Solvents; Ultrasonics

2010
Tumor eradication by immunotherapy with biodegradable PLGA microspheres--an alternative to incomplete Freund's adjuvant.
    International journal of cancer, 2011, Jul-15, Volume: 129, Issue:2

    Topics: Animals; CD8-Positive T-Lymphocytes; Disease Models, Animal; Freund's Adjuvant; Immunotherapy; Lactic Acid; Lipids; Melanoma; Mice; Mice, Inbred C57BL; Microspheres; Oligodeoxyribonucleotides; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes, Cytotoxic; Thymoma; Thymus Neoplasms; Treatment Outcome

2011
In vivo evidence of oral vaccination with PLGA nanoparticles containing the immunostimulant monophosphoryl lipid A.
    Biomaterials, 2011, Volume: 32, Issue:16

    Topics: Adjuvants, Immunologic; Animals; Enzyme-Linked Immunosorbent Assay; Lactic Acid; Lipid A; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccination

2011
Activation of antigen-specific T cell-responses by mannan-decorated PLGA nanoparticles.
    Pharmaceutical research, 2011, Volume: 28, Issue:9

    Topics: Animals; Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Dendritic Cells; Drug Carriers; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Lactic Acid; Lectins, C-Type; Lymph Nodes; Lymphocyte Activation; Male; Mannans; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface; Spleen; T-Lymphocytes; Vaccines

2011
Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Feb-10, Volume: 157, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Antigens; Biomimetics; Cells, Cultured; Dendritic Cells; Female; Galactosylceramides; Immunoglobulin G; Lactic Acid; Lipid A; Lipids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Vaccines, Subunit

2012
Encapsulation of antigen in poly(D,L-lactide-co-glycolide) microspheres protects from harmful effects of γ-irradiation as assessed in mice.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012, Volume: 80, Issue:2

    Topics: Animals; Antigens; Cost-Benefit Analysis; Dendritic Cells; Female; Gamma Rays; Humans; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Microspheres; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sterilization; T-Lymphocytes; Vaccines

2012
Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Mar-10, Volume: 158, Issue:2

    Topics: Animals; Antigens; Capsules; CD4-Positive T-Lymphocytes; Cytokines; Dextran Sulfate; Drug Compounding; Female; Immunization; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred C57BL; Ovalbumin; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2012
Preparation and evaluation of mannose receptor mediated macrophage targeting delivery system.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Animals; Cell Line; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Flow Cytometry; Kinetics; Lactic Acid; Lectins, C-Type; Macrophages; Magnetic Resonance Spectroscopy; Mannose; Mannose Receptor; Mannose-Binding Lectins; Mice; Microscopy, Confocal; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Receptors, Cell Surface; Solubility; Spectrometry, Fluorescence; Technology, Pharmaceutical

2011
Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Sep-10, Volume: 162, Issue:2

    Topics: Administration, Inhalation; Animals; Antigens; Bronchial Hyperreactivity; Delayed-Action Preparations; Drug Carriers; Guinea Pigs; Heparin; Lactic Acid; Lung; Male; Nebulizers and Vaporizers; Ovalbumin; Pneumonia; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solutions

2012
Drug delivery to inflamed colon by nanoparticles: comparison of different strategies.
    International journal of pharmaceutics, 2013, Jan-02, Volume: 440, Issue:1

    Topics: Animals; Caco-2 Cells; Chitosan; Colitis; Cytokines; Dextran Sulfate; Drug Carriers; Ethylene Oxide; Female; Humans; Inflammatory Bowel Diseases; Intestinal Absorption; Lactic Acid; Lactones; Mannose; Mice; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymethacrylic Acids

2013
Biodegradable particles as vaccine delivery systems: size matters.
    The AAPS journal, 2013, Volume: 15, Issue:1

    Topics: Animals; Dendritic Cells; Drug Delivery Systems; Immunoglobulin G; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes, Cytotoxic; Vaccines

2013
PLGA nanoparticles enhance the expression of retinaldehyde dehydrogenase enzymes in dendritic cells and induce FoxP3(+) T-cells in vitro.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, May-28, Volume: 168, Issue:1

    Topics: Aldehyde Dehydrogenase 1 Family; Animals; CD4-Positive T-Lymphocytes; Cytokines; Dendritic Cells; Female; Forkhead Transcription Factors; Isoenzymes; Lactic Acid; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Transgenic; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Antigen, T-Cell; Retinal Dehydrogenase

2013
In vitro evaluation of the effects of various additives and polymers on nerve growth factor microspheres.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:4

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Excipients; Glucose; Lactic Acid; Microspheres; Nerve Growth Factor; Ovalbumin; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine

2014
Preparation and evaluation of double-walled microparticles prepared with a modified water-in-oil-in-oil-in-water (w1/o/o/w3) method.
    Journal of microencapsulation, 2013, Volume: 30, Issue:8

    Topics: Delayed-Action Preparations; Emulsions; Lactic Acid; Oils; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Water

2013
Inhalable DNase I microparticles engineered with biologically active excipients.
    Pulmonary pharmacology & therapeutics, 2013, Volume: 26, Issue:6

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Inhalation; Aerosols; Animals; Chitosan; Cystic Fibrosis; Delayed-Action Preparations; Deoxyribonuclease I; Dextrans; Drug Carriers; Drug Delivery Systems; Epithelial Cells; Excipients; Lactic Acid; Macrophages; Mice; Mucus; Ovalbumin; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Viscosity

2013
Low-molecular-weight heparin (LMWH)-loaded large porous PEG-PLGA particles for the treatment of asthma.
    Journal of aerosol medicine and pulmonary drug delivery, 2014, Volume: 27, Issue:1

    Topics: Administration, Inhalation; Airway Remodeling; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Goblet Cells; Heparin, Low-Molecular-Weight; Hyperplasia; Inflammation Mediators; Lactic Acid; Lung; Male; Ovalbumin; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats; Rats, Sprague-Dawley; Time Factors

2014
Microsphere priming facilitates induction of potent therapeutic T-cell immune responses against autochthonous liver cancers.
    European journal of immunology, 2014, Volume: 44, Issue:4

    Topics: Animals; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cytokines; Flow Cytometry; Immunization, Secondary; Immunotherapy; Lactic Acid; Listeria monocytogenes; Listeriosis; Liver Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Microspheres; Ovalbumin; Poly I-C; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Survival Analysis; Toll-Like Receptor 3; Treatment Outcome; Vaccination

2014
Polymer nanoparticles for enhanced immune response: combined delivery of tumor antigen and small interference RNA for immunosuppressive gene to dendritic cells.
    Acta biomaterialia, 2014, Volume: 10, Issue:5

    Topics: Animals; Antigens, Neoplasm; CD8-Positive T-Lymphocytes; Cell Survival; Chickens; Cytokines; Dendritic Cells; Endocytosis; Female; Gene Silencing; Gene Transfer Techniques; Immunity; Immunosuppression Therapy; Inflammation Mediators; Lactic Acid; Mice; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins

2014
Characterization of protein-adjuvant coencapsulation in microparticles for vaccine delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 87, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Chemistry, Pharmaceutical; Drug Carriers; Lactic Acid; Molecular Weight; Osmolar Concentration; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Technology, Pharmaceutical; Vaccines

2014
Aerosolized montelukast polymeric particles-an alternative to oral montelukast-alleviate symptoms of asthma in a rodent model.
    Pharmaceutical research, 2014, Volume: 31, Issue:11

    Topics: Acetates; Aerosols; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cyclopropanes; Cysteine; Disease Models, Animal; Inflammation; L-Lactate Dehydrogenase; Lactic Acid; Leukotrienes; Lung; Ovalbumin; Peroxidase; Polyesters; Polymers; Quinolines; Rats; Rats, Sprague-Dawley; Sulfides

2014
Time course study of the antigen-specific immune response to a PLGA microparticle vaccine formulation.
    Biomaterials, 2014, Volume: 35, Issue:29

    Topics: Adjuvants, Immunologic; Animals; Drug Carriers; Female; Immunity, Cellular; Immunoglobulin G; Lactic Acid; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccination; Vaccines

2014
Targeting nanoparticles to CD40, DEC-205 or CD11c molecules on dendritic cells for efficient CD8(+) T cell response: a comparative study.
    Journal of controlled release : official journal of the Controlled Release Society, 2014, Oct-28, Volume: 192

    Topics: Animals; Antigens, CD; CD11c Antigen; CD40 Antigens; CD8-Positive T-Lymphocytes; Dendritic Cells; Drug Delivery Systems; Lactic Acid; Lectins, C-Type; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface

2014
Efficient nanoparticle-mediated needle-free transcutaneous vaccination via hair follicles requires adjuvantation.
    Nanomedicine : nanotechnology, biology, and medicine, 2015, Volume: 11, Issue:1

    Topics: Adjuvants, Immunologic; Administration, Cutaneous; Animals; Antigens; Cell Proliferation; Chitosan; Cytokines; Drug Carriers; Female; Immunity, Humoral; Lactic Acid; Mice; Mice, Inbred C57BL; Nanomedicine; Nanoparticles; Needles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Vaccination

2015
Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Jan-13, Volume: 112, Issue:2

    Topics: Animals; Antigens; CD4-Positive T-Lymphocytes; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Factor VIII; Female; Hemocyanins; Hemophilia A; Humans; Hypersensitivity, Delayed; Immune Tolerance; Immunity, Humoral; Immunosuppression Therapy; Immunosuppressive Agents; Lactic Acid; Mice; Mice, Inbred BALB C; Nanocapsules; Nanoparticles; Oligodeoxyribonucleotides; Ovalbumin; Peptide Fragments; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteins; Recombinant Proteins; Sirolimus

2015
Poly-(lactic-co-glycolic-acid)-based particulate vaccines: particle uptake by dendritic cells is a key parameter for immune activation.
    Vaccine, 2015, Feb-11, Volume: 33, Issue:7

    Topics: Animals; Antibody Formation; CD8-Positive T-Lymphocytes; Dendritic Cells; Lactic Acid; Mice; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccines

2015
Co-encapsulated CpG oligodeoxynucleotides and ovalbumin in PLGA microparticles; an in vitro and in vivo study.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2014, Volume: 17, Issue:4

    Topics: Animals; Antibody Formation; Antigens; Female; Immunization; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microspheres; Oligodeoxyribonucleotides; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccines

2014
Inverse micellar sugar glass (IMSG) nanoparticles for transfollicular vaccination.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, May-28, Volume: 206

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antigens; Carbohydrates; Chitosan; Drug Carriers; Female; Hair Follicle; Immunity, Cellular; Immunity, Humoral; Injections, Intradermal; Lactic Acid; Mice, Inbred C57BL; Micelles; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccination

2015
Controlled and Extended Release of a Model Protein from a Microsphere-Hydrogel Drug Delivery System.
    Annals of biomedical engineering, 2015, Volume: 43, Issue:11

    Topics: Acrylic Resins; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Hydrogels; Lactic Acid; Microspheres; Ovalbumin; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2015
pH-Responsive Poly(D,L-lactic-co-glycolic acid) Nanoparticles with Rapid Antigen Release Behavior Promote Immune Response.
    ACS nano, 2015, May-26, Volume: 9, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Antigen Presentation; Antigens; Dendritic Cells; Drug Carriers; Drug Liberation; Hydrogen-Ion Concentration; Immunity, Cellular; Intracellular Space; Lactic Acid; Lymphocyte Activation; Mice; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Time Factors; Vaccines

2015
Optimization of nanoparticles for cardiovascular tissue engineering.
    Nanotechnology, 2015, Jun-12, Volume: 26, Issue:23

    Topics: Cardiovascular Physiological Phenomena; Drug Delivery Systems; Lactic Acid; Materials Testing; Nanoparticles; Neural Networks, Computer; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Tissue Engineering

2015
Immunopotentiator-Loaded Polymeric Microparticles as Robust Adjuvant to Improve Vaccine Efficacy.
    Pharmaceutical research, 2015, Volume: 32, Issue:9

    Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Aminoquinolines; Animals; Antigens; Female; Imiquimod; Immunity, Cellular; Immunoglobulin G; Influenza A Virus, H5N1 Subtype; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vaccines

2015
Photosensitizer and Light Pave the Way for Cytosolic Targeting and Generation of Cytosolic CD8 T Cells Using PLGA Vaccine Particles.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Jul-01, Volume: 195, Issue:1

    Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cancer Vaccines; Cytosol; Dendritic Cells; Drug Carriers; Female; Granzymes; Immunization; Injections, Intradermal; Interleukin-2; Lactic Acid; Light; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Targeted Therapy; Neoplasm Transplantation; Ovalbumin; Photosensitizing Agents; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porphyrins; Skin Neoplasms; T-Lymphocytes, Cytotoxic; Tumor Necrosis Factor-alpha

2015
Diaminosulfide based polymer microparticles as cancer vaccine delivery systems.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Dec-28, Volume: 220, Issue:Pt B

    Topics: Adjuvants, Immunologic; Animals; Cancer Vaccines; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Freund's Adjuvant; Immunity, Cellular; Immunity, Humoral; Lactic Acid; Male; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sulfides; Thymoma; Thymus Neoplasms; Time Factors; Transfection; Tumor Burden; Vaccination

2015
Functional characterization of biodegradable nanoparticles as antigen delivery system.
    Journal of experimental & clinical cancer research : CR, 2015, Oct-06, Volume: 34

    Topics: Animals; Antigen Presentation; Antigens; Cancer Vaccines; Caveolin 1; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Clathrin; Dendritic Cells; Humans; Immunologic Memory; Lactic Acid; Mice; Microscopy, Confocal; Multivesicular Bodies; Nanoparticles; Ovalbumin; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes, Cytotoxic; Vaccines, Subunit

2015
Activation of Antigen-Specific CD8(+) T Cells by Poly-DL-Lactide/Glycolide (PLGA) Nanoparticle-Primed Gr-1(high) Cells.
    Pharmaceutical research, 2016, Volume: 33, Issue:4

    Topics: Animals; Antigen Presentation; Apoptosis; Bone Marrow Cells; CD11b Antigen; CD8-Positive T-Lymphocytes; Cell Cycle; Cells, Cultured; Coculture Techniques; Immunization; Lactic Acid; Lymphocyte Activation; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface

2016
Impact of PEG and PEG-b-PAGE modified PLGA on nanoparticle formation, protein loading and release.
    International journal of pharmaceutics, 2016, Mar-16, Volume: 500, Issue:1-2

    Topics: Drug Liberation; Epoxy Compounds; Lactic Acid; Nanoparticles; Ovalbumin; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties

2016
Immune responses to vaccines delivered by encapsulation into and/or adsorption onto cationic lipid-PLGA hybrid nanoparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, Mar-10, Volume: 225

    Topics: Adsorption; Animals; Antigens; B7-2 Antigen; Biological Transport; Cholesterol; Dendritic Cells; Female; Immunoglobulin G; Interferon-gamma; Interleukin-4; Lactic Acid; Lymph Nodes; Major Histocompatibility Complex; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spleen; Vaccines

2016
Synthetic long peptide-based vaccine formulations for induction of cell mediated immunity: A comparative study of cationic liposomes and PLGA nanoparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, Mar-28, Volume: 226

    Topics: Amino Acid Sequence; Animals; Cancer Vaccines; Cations; CD8-Positive T-Lymphocytes; Female; Immunity, Cellular; Immunization; Lactic Acid; Liposomes; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Ovalbumin; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccines, Synthetic

2016
Development and Evaluation of Biodegradable Particles Coloaded With Antigen and the Toll-Like Receptor Agonist, Pentaerythritol Lipid A, as a Cancer Vaccine.
    Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Antigens; Biocompatible Materials; Cancer Vaccines; Chemistry, Pharmaceutical; Cytokines; Dendritic Cells; Female; Lactic Acid; Lipid A; Mice; Mice, Inbred C57BL; Neoplasms; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propylene Glycols; Toll-Like Receptors

2016
PLGA-Listeriolysin O microspheres: Opening the gate for cytosolic delivery of cancer antigens.
    Biomedical microdevices, 2016, Volume: 18, Issue:2

    Topics: Animals; Antigen-Presenting Cells; Antigens, Neoplasm; Bacterial Toxins; Biological Transport; Cell Survival; Cross-Priming; Cytosol; Drug Carriers; Drug Liberation; Heat-Shock Proteins; Hemolysin Proteins; Lactic Acid; Mice; Microspheres; Ovalbumin; Peptides; Phagocytes; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RAW 264.7 Cells

2016
A biodegradable killer microparticle to selectively deplete antigen-specific T cells in vitro and in vivo.
    Oncotarget, 2016, Mar-15, Volume: 7, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Epitopes, T-Lymphocyte; Graft Rejection; Graft Survival; Lactic Acid; Lymphocyte Depletion; Major Histocompatibility Complex; Male; Mice; Mice, Inbred C57BL; Microspheres; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes

2016
Antigen delivery via hydrophilic PEG-b-PAGE-b-PLGA nanoparticles boosts vaccination induced T cell immunity.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 102

    Topics: Adjuvants, Immunologic; Animals; Antigen Presentation; Antigens; Chemistry, Pharmaceutical; Cross-Priming; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nanoparticles; Ovalbumin; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Vaccination; Vaccines

2016
Polymer nanoparticles for cross-presentation of exogenous antigens and enhanced cytotoxic T-lymphocyte immune response.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: Animals; Antigens; Cell Differentiation; Cell Survival; Cross-Priming; Dendritic Cells; Endocytosis; Female; Intracellular Space; Lactic Acid; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes, Cytotoxic

2016
In Vitro Evaluation of the Biological Responses of Canine Macrophages Challenged with PLGA Nanoparticles Containing Monophosphoryl Lipid A.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Biological Transport; Cell Survival; Dogs; Drug Carriers; Drug Compounding; Female; Gene Expression; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Interleukin-10; Interleukin-12 Subunit p40; Lactic Acid; Lipid A; Macrophages; Male; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Primary Cell Culture; Trypan Blue; Tumor Necrosis Factor-alpha

2016
Induction of a balanced Th1/Th2 immune responses by co-delivery of PLGA/ovalbumin nanospheres and CpG ODNs/PEI-SWCNT nanoparticles as TLR9 agonist in BALB/c mice.
    International journal of pharmaceutics, 2016, Dec-30, Volume: 515, Issue:1-2

    Topics: Adjuvants, Immunologic; Animals; Antigen-Presenting Cells; Cell Line; Female; Lactic Acid; Macrophages; Mice; Mice, Inbred BALB C; Nanospheres; Nanotubes, Carbon; Oligodeoxyribonucleotides; Ovalbumin; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Th1 Cells; Th2 Cells; Toll-Like Receptor 9

2016
Nanotechnology-Based Cancer Vaccine.
    Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1530

    Topics: Animals; Cancer Vaccines; Dendritic Cells; Disease Models, Animal; Humans; Immunotherapy; Lactic Acid; Lymphocyte Activation; Melanoma, Experimental; Nanoparticles; Nanotechnology; Neoplasms; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocyte Subsets; Vaccination

2017
Rational design of nanoparticles towards targeting antigen-presenting cells and improved T cell priming.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, 07-28, Volume: 258

    Topics: Animals; Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Dendritic Cells; Drug Delivery Systems; Female; Immunization; Lactic Acid; Lymph Nodes; Lymphocyte Activation; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents

2017
Self-encapsulating Poly(lactic-co-glycolic acid) (PLGA) Microspheres for Intranasal Vaccine Delivery.
    Molecular pharmaceutics, 2017, 09-05, Volume: 14, Issue:9

    Topics: Animals; Calcium Phosphates; Cholera Toxin; Chromatography, High Pressure Liquid; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Female; Lactic Acid; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Microspheres; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccines

2017
Exploring the immunopotentiation of Chinese yam polysaccharide poly(lactic-co-glycolic acid) nanoparticles in an ovalbumin vaccine formulation in vivo.
    Drug delivery, 2017, Volume: 24, Issue:1

    Topics: Animals; CD8-Positive T-Lymphocytes; Dioscorea; Glycols; Lactic Acid; Mice; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polysaccharides; Vaccines

2017
Hollow microneedle-mediated intradermal delivery of model vaccine antigen-loaded PLGA nanoparticles elicits protective T cell-mediated immunity to an intracellular bacterium.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, Nov-28, Volume: 266

    Topics: Animals; Antigens; Injections, Intradermal; Lactic Acid; Listeria monocytogenes; Male; Mice, Transgenic; Microinjections; Nanoparticles; Needles; Ovalbumin; Poly I-C; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Toll-Like Receptor 3; Vaccination; Vaccines

2017
Intradermal vaccination with hollow microneedles: A comparative study of various protein antigen and adjuvant encapsulated nanoparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2017, Nov-28, Volume: 266

    Topics: Adjuvants, Immunologic; Animals; Antigens; Drug Liberation; Female; Injections, Intradermal; Lactic Acid; Liposomes; Mice, Inbred BALB C; Mice, Inbred C57BL; Microinjections; Nanoparticles; Needles; Ovalbumin; Poly I-C; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccination

2017
Improving release completeness from PLGA-based implants for the acid-labile model protein ovalbumin.
    International journal of pharmaceutics, 2018, Mar-01, Volume: 538, Issue:1-2

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Implants; Drug Liberation; Excipients; Hydrogen-Ion Concentration; Lactic Acid; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Resins, Plant; Solubility

2018
Design and immunological evaluation of anti-CD205-tailored PLGA-based nanoparticulate cancer vaccine.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Antigens, CD; Cancer Vaccines; Cell Line; Coumarins; Cytokines; Dendritic Cells; Immunotherapy; Lactic Acid; Lectins, C-Type; Lipid A; Mice; Minor Histocompatibility Antigens; Nanoparticles; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface; T-Lymphocytes

2018
Dual dye in-vivo imaging of differentially charged PLGA carriers reveals antigen-depot effect, leading to improved immune responses in preclinical models.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, May-30, Volume: 117

    Topics: Adjuvants, Immunologic; Animals; Antigens; Carbocyanines; Cytokines; Drug Carriers; Drug Evaluation, Preclinical; Fluorescent Dyes; Immunoglobulin G; Lactic Acid; Male; Mice, Hairless; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2018
Development of PLGA nanoparticle loaded dissolving microneedles and comparison with hollow microneedles in intradermal vaccine delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 129

    Topics: Adjuvants, Immunologic; Administration, Cutaneous; Animals; Drug Liberation; Female; Humans; Hyaluronic Acid; Immunity, Cellular; Immunity, Humoral; Injections, Intradermal; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microinjections; Nanoparticles; Needles; Ovalbumin; Poly I-C; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Vaccination; Vaccines

2018
Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
    Scientific reports, 2020, 02-06, Volume: 10, Issue:1

    Topics: Animals; Asthma; Bronchoconstrictor Agents; Cells, Cultured; Disease Models, Animal; Female; Glycolysis; Humans; Hydrogen; Lactic Acid; Leukocytes, Mononuclear; Lung; Male; Methacholine Chloride; Mice; Middle Aged; Ovalbumin; Oxidative Phosphorylation; Primary Cell Culture

2020
Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization.
    Journal of visualized experiments : JoVE, 2022, 09-02, Issue:187

    Topics: Antigens; Emulsions; Lactic Acid; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Vaccines

2022