lactic acid and oligonucleotides

lactic acid has been researched along with oligonucleotides in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.33)18.2507
2000's13 (54.17)29.6817
2010's9 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ando, H; Asakawa, N; Ishida, M; Kato, T; Yamakawa, I1
Allémann, E; Benimetskaya, L; Berton, M; Gurny, R; Stein, CA1
Allémann, E; Berton, M; Gurny, R; Stein, CA; Trono, D; Turelli, P1
Alphandary, H; Appel, M; De Rosa, G; Fattal, E; La Rotonda, MI; Quaglia, F1
Currier, BL; Lu, L; Windebank, AJ; Yaszemski, MJ; Zhu, X1
Gill, JS; Lu, L; Moore, MJ; Windebank, AJ; Yaszemski, MJ; Zhu, X1
Besnard, M; De Rosa, G; Fattal, E; La Rotonda, M; Quaglia, F1
Adamis, AP; Carrasquillo, KG; Gragoudas, ES; Miller, JW; Ricker, JA; Rigas, IK1
De Rosa, G; Miro, A; Quaglia, F; Ungaro, F1
Farokhzad, OC; Jon, S; Khademhosseini, A; Langer, R; Lavan, DA; Tran, TN1
Carnuccio, R; De Rosa, G; De Stefano, D; La Rotonda, MI; Maiuri, MC; Quaglia, F; Ungaro, F1
Hu, Y; Sun, WQ; Wang, HF; Wei, WN; Xie, CS; Yao, JX; Zheng, JE1
Hartmann, G1
Choleris, E; Langer, R; Little, SR; Mong, JA; Pfaff, DW; Puram, SV1
Basta, S; Busch, DH; Fischer, S; Gander, B; Groettrup, M; Mueller, M; Schlosser, E1
Chin, JY; Fields, RJ; Glazer, PM; McNeer, NA; Saltzman, WM; Schleifman, EB1
Bando, Y; Kawashima, Y; Morishita, R; Samura, S; Tahara, K; Tsuji, K; Tsujimoto, H; Tsukada, Y; Yamamoto, H1
Cordido, F; Helmling, S; Klussmann, S; Sangiao-Alvarellos, S; Vázquez, MJ1
Arima, Y; Iwata, H; Matsui, T; Takemoto, N1
Beeks, CG; Hinchman, AN; Klimecki, WT; Li, H; Malm, SW; Zhao, F1
Hu, F; Liang, G; Sun, B; Tian, T; Xiao, Z; Zhu, Y1
Ambrosini, V; Caputo, P; Costabile, G; d'Angelo, I; d'Emmanuele di Villa Bianca, R; Donnarumma, G; Miro, A; Perfetto, B; Quaglia, F; Sorrentino, R; Ungaro, F1
Guo, RM; Jiao, J; Zhang, Y; Zhu, S; Zou, MH; Zou, Q1
Chitnis, NB; Gupta, SK; Kushwaha, H; Nalage, VHH; Salvi, D; Sharma, A; Shukla, P; Srivastava, SK1

Other Studies

24 other study(ies) available for lactic acid and oligonucleotides

ArticleYear
Release behavior of poly(lactic acid-co-glycolic acid) implants containing phosphorothioate oligodeoxynucleotide.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:4

    Topics: Animals; Biocompatible Materials; Cattle; Drug Implants; Lactic Acid; Molecular Weight; Oligonucleotides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prostheses and Implants; Thionucleotides; Vitreous Body

1997
Uptake of oligonucleotide-loaded nanoparticles in prostatic cancer cells and their intracellular localization.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 1999, Volume: 47, Issue:2

    Topics: Humans; Lactic Acid; Male; Oligonucleotides; Polyesters; Polymers; Prostatic Neoplasms; Thionucleotides; Tumor Cells, Cultured

1999
Inhibition of HIV-1 in cell culture by oligonucleotide-loaded nanoparticles.
    Pharmaceutical research, 2001, Volume: 18, Issue:8

    Topics: Cell Survival; Cells, Cultured; Drug Compounding; Excipients; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Indicators and Reagents; Lactic Acid; Lymphocytes; Microspheres; Oligonucleotides; Oligonucleotides, Antisense; Polyesters; Polymers; Reverse Transcriptase Inhibitors; Transfection; Virus Replication

2001
Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:3

    Topics: Biocompatible Materials; Cell Membrane Permeability; Cell Survival; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; HeLa Cells; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Microspheres; Oligonucleotides; Particle Size; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility

2002
Controlled release of NFkappaB decoy oligonucleotides from biodegradable polymer microparticles.
    Biomaterials, 2002, Volume: 23, Issue:13

    Topics: Biocompatible Materials; Drug Delivery Systems; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; NF-kappa B; Oligonucleotides; Oligonucleotides, Antisense; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Time Factors

2002
Effects of NFkappaB decoy oligonucleotides released from biodegradable polymer microparticles on a glioblastoma cell line.
    Biomaterials, 2002, Volume: 23, Issue:13

    Topics: Active Transport, Cell Nucleus; Biocompatible Materials; Biodegradation, Environmental; Blotting, Western; Cell Division; Cell Line; Cells, Cultured; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Glioblastoma; Humans; Immunoblotting; Kinetics; Lactic Acid; Neuroglia; NF-kappa B; Oligonucleotides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proto-Oncogene Proteins; Time Factors; Tumor Cells, Cultured

2002
Biodegradable microparticles for the controlled delivery of oligonucleotides.
    International journal of pharmaceutics, 2002, Aug-21, Volume: 242, Issue:1-2

    Topics: Delayed-Action Preparations; Drug Carriers; Drug Compounding; HeLa Cells; Humans; Lactic Acid; Microscopy, Confocal; Microspheres; Oligonucleotides; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2002
Controlled delivery of the anti-VEGF aptamer EYE001 with poly(lactic-co-glycolic)acid microspheres.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:1

    Topics: Animals; Biocompatible Materials; Cell Division; Cells, Cultured; Circular Dichroism; Drug Carriers; Drug Delivery Systems; Endothelium, Vascular; Humans; Lactic Acid; Microspheres; Oligonucleotides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Sclera; Umbilical Veins

2003
Spectrophotometric determination of polyethylenimine in the presence of an oligonucleotide for the characterization of controlled release formulations.
    Journal of pharmaceutical and biomedical analysis, 2003, Feb-05, Volume: 31, Issue:1

    Topics: Algorithms; Copper; Delayed-Action Preparations; Excipients; Hydrogen-Ion Concentration; Indicators and Reagents; Lactic Acid; Microspheres; Oligonucleotides; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Reference Standards; Reproducibility of Results; Sodium Hydroxide; Spectrophotometry, Ultraviolet

2003
Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells.
    Cancer research, 2004, Nov-01, Volume: 64, Issue:21

    Topics: Antigens, Surface; Cell Line, Tumor; Drug Delivery Systems; Glutamate Carboxypeptidase II; Humans; Lactic Acid; Male; Oligonucleotides; Polyesters; Polyethylene Glycols; Polymers; Prostatic Neoplasms

2004
Enhanced intracellular uptake and inhibition of NF-kappaB activation by decoy oligonucleotide released from PLGA microspheres.
    The journal of gene medicine, 2005, Volume: 7, Issue:6

    Topics: Animals; Cell Line; Delayed-Action Preparations; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Gene Transfer Techniques; Lactic Acid; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Microscopy, Electron, Scanning; Microspheres; Mutation; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oligonucleotides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Time Factors; Tumor Necrosis Factor-alpha

2005
[Regulation of tissue factor expression in brain microvascular endothelial cells by PLA nanoparticles coating NF-kappaB decoy oligonucleotides].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2005, Volume: 26, Issue:9

    Topics: Animals; Brain; Capillaries; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Lactic Acid; Nanoparticles; NF-kappa B; Oligonucleotides; Polyesters; Polymers; Rats; Thromboplastin; Transfection

2005
TIDES 2006--IBC conference. Oligonucleotide and peptide technology and product development. 1-3 May 2006, Carlsbad, CA, USA.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:7

    Topics: Antiviral Agents; California; Drug Delivery Systems; Drug Design; Humans; Lactic Acid; Liposomes; Microspheres; Oligonucleotides; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Retinal Diseases; RNA, Small Interfering; Toll-Like Receptor 9; Transforming Growth Factor beta; Transforming Growth Factor beta2

2006
Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Mar-13, Volume: 104, Issue:11

    Topics: Amygdala; Animals; Behavior, Animal; Female; Lactic Acid; Male; Mice; Microspheres; Molecular Weight; Oligonucleotides; Oligonucleotides, Antisense; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Receptors, Oxytocin; Risk Assessment; Sexual Behavior, Animal

2007
TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses.
    Vaccine, 2008, Mar-20, Volume: 26, Issue:13

    Topics: Adjuvants, Immunologic; Animals; Antigens; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Cell Survival; CpG Islands; Cytokines; Dendritic Cells; Drug Compounding; Excipients; Flow Cytometry; Immunity, Cellular; Interferon Inducers; Lactic Acid; Ligands; Mice; Mice, Inbred C57BL; Microspheres; Myosin Heavy Chains; Oligonucleotides; Poly I-C; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes, Cytotoxic; Toll-Like Receptors

2008
Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2011, Volume: 19, Issue:1

    Topics: Antigens, CD34; beta-Globins; Cell Survival; Cells, Cultured; DNA; Gene Targeting; Gene Transfer Techniques; Genome; Hematopoietic Stem Cells; Humans; Lactic Acid; Nanoparticles; Oligonucleotides; Particle Size; Peptide Nucleic Acids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, CCR5; Recombination, Genetic; Targeted Gene Repair

2011
Oral nuclear factor-κB decoy oligonucleotides delivery system with chitosan modified poly(D,L-lactide-co-glycolide) nanospheres for inflammatory bowel disease.
    Biomaterials, 2011, Volume: 32, Issue:3

    Topics: Animals; Chitosan; Drug Carriers; Inflammatory Bowel Diseases; Lactic Acid; Male; Nanospheres; NF-kappa B; Oligonucleotides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar

2011
Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism.
    Molecular and cellular endocrinology, 2011, Mar-30, Volume: 335, Issue:2

    Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Eating; Energy Metabolism; Food Deprivation; Ghrelin; Glucokinase; Glucose; Glycogen; Growth Hormone; Hexokinase; Insulin; Lactic Acid; Lipogenesis; Liver; Male; Oligonucleotides; Pyruvate Kinase; Rats; Rats, Wistar; Transcription, Genetic; Triglycerides; Weight Gain

2011
Cell patterning on polylactic acid through surface-tethered oligonucleotides.
    Acta biomaterialia, 2015, Volume: 13

    Topics: Animals; Cattle; Cell Adhesion; Cytoskeleton; DNA, Single-Stranded; HEK293 Cells; Humans; Lactic Acid; Oligonucleotides; Phospholipids; Polyesters; Polyethylene Glycols; Polymers; Tissue Scaffolds

2015
Arsenite-induced pseudo-hypoxia results in loss of anchorage-dependent growth in BEAS-2B pulmonary epithelial cells.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Alveolar Epithelial Cells; Analysis of Variance; Arsenites; Cell Hypoxia; Cell Line; Energy Metabolism; Fluorescent Antibody Technique; Gas Chromatography-Mass Spectrometry; Glycolysis; Half-Life; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Lactic Acid; Metabolomics; Oligonucleotides; Real-Time Polymerase Chain Reaction

2014
A novel type of self-assembled nanoparticles as targeted gene carriers: an application for plasmid DNA and antimicroRNA oligonucleotide delivery.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: Apoptosis; Blotting, Western; Cell Cycle; DNA; Drug Carriers; Gene Transfer Techniques; Genetic Therapy; Hep G2 Cells; Humans; Lactic Acid; MicroRNAs; Nanoparticles; Oligonucleotides; Particle Size; Plasmids; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Transfection; Tumor Cells, Cultured

2016
Large Porous Particles for Sustained Release of a Decoy Oligonucelotide and Poly(ethylenimine): Potential for Combined Therapy of Chronic Pseudomonas aeruginosa Lung Infections.
    Biomacromolecules, 2016, 05-09, Volume: 17, Issue:5

    Topics: Animals; Chronic Disease; Drug Carriers; Humans; Lactic Acid; Male; Oligonucleotides; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Wistar; Respiratory Tract Infections

2016
Aptamer-modified PLGA nanoparticle delivery of triplex forming oligonucleotide for targeted prostate cancer therapy.
    Neoplasma, 2016, Volume: 63, Issue:4

    Topics: Animals; Aptamers, Nucleotide; Cell Line, Tumor; Humans; Lactic Acid; Male; Mice; Nanoparticles; Nanotechnology; Oligonucleotides; Polyesters; Polyethylene Glycols; Prostatic Neoplasms

2016
Metabolic engineering of CHO cells for the development of a robust protein production platform.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Bioreactors; Carbon; CHO Cells; Citric Acid Cycle; Cricetinae; Cricetulus; Cytoplasm; Cytosol; Energy Metabolism; Gene Dosage; Glucose; Glutamine; Glycosylation; Lactates; Lactic Acid; Metabolic Engineering; Mitochondria; Oligonucleotides; Oxidation-Reduction; Polysaccharides; Pyruvate Carboxylase; Pyruvic Acid; Saccharomyces cerevisiae

2017