lactic acid and nimodipine

lactic acid has been researched along with nimodipine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's2 (11.11)18.2507
2000's6 (33.33)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Kostron, H; Murr, C; Pillwein, K; Sperl, W1
Chen, BT; Feng, YP; Sun, YD; Ye, G; Zeng, GY1
Adams, HA; Börner, U; Hempelmann, G; Müller, H; von Bormann, B1
Bielenberg, GW; Krieglstein, J; Stierstorfer, HJ; Weber, J1
Michenfelder, JD; Milde, JH; Milde, LN1
Michenfelder, JD; Milde, JH1
Nedergaard, M1
Okada, Y; Sakurai, T; Takata, T; Yang, B; Yokono, K1
Ak, A; Bor, MA; Duman, A; Oğün, CO; Ustün, ME1
Engel, J; Fritz, T; Hempelmann, G; Kuhn, DF; Oehmke, MJ; Schirrmeister, D1
Mehta, AK; Sawant, KK; Yadav, KS1
Gao, H; Gu, Y; Ping, Q1
Bege, N; Beseoglu, K; Eicker, S; Etminan, N; Frauenknecht, K; Hänggi, D; Heiroth, HJ; Kamp, MA; Kissel, T; Macht, S; Perrin, J; Sommer, C; Steiger, HJ1
Choi, P; Lavasanifar, A; Soleymani Abyaneh, H; Vakili, MR; Zhang, F1
Askin, S; Craig, DQ; Guo, ZF; Liu, Y; Yang, F; Zhang, YM; Zhao, M1
Algeri, R; Easwaran, M; Mugesh Kanna, R; Murugan, C; Pushpa, BT; Rajasekaran, S; Shetty, AP; Sri Vijay Anand, KS1

Trials

2 trial(s) available for lactic acid and nimodipine

ArticleYear
[Effect of nimodipine on plasma catecholamines and perioperative endocrine stress parameters].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1988, Volume: 23, Issue:2

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Anesthesia, General; Blood Glucose; Epinephrine; Female; Glycerol; Humans; Hydrocortisone; Lactates; Lactic Acid; Male; Middle Aged; Nimodipine; Norepinephrine; Premedication; Stress, Physiological; Vasopressins

1988
Perioperative changes in cerebral ischemic markers in the cerebrospinal fluid after preoperative nimodipine treatment.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:10

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Arthroplasty, Replacement, Hip; Biomarkers; Brain Ischemia; Calcium Channel Blockers; Cerebrospinal Fluid; Creatine Kinase; Double-Blind Method; Female; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Infusions, Intravenous; Intraoperative Complications; Lactic Acid; Male; Neuroprotective Agents; Nimodipine; Phosphopyruvate Hydratase; Preoperative Care; Prospective Studies

2003

Other Studies

16 other study(ies) available for lactic acid and nimodipine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Effect of the calcium entry blocker nimodipine on the metabolism of nucleic acids in rat brain ischemia.
    Advances in neurology, 1990, Volume: 52

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Animals; Brain Chemistry; Brain Ischemia; Energy Metabolism; Lactates; Lactic Acid; Male; Nimodipine; Rats; Reperfusion

1990
[Brain energy metabolism of cerebral ischemic mice and the effects of some drugs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1989, Volume: 24, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Ginsenosides; Lactates; Lactic Acid; Male; Mice; Nimodipine; Phenobarbital; Phosphocreatine; Saponins

1989
Nimodipine reduces postischemic lactate levels in the isolated perfused rat brain.
    Biochemical pharmacology, 1989, Mar-01, Volume: 38, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; In Vitro Techniques; Lactates; Lactic Acid; Male; Nimodipine; Perfusion; Rats; Rats, Inbred Strains

1989
Delayed treatment with nimodipine improves cerebral blood flow after complete cerebral ischemia in the dog.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:3

    Topics: Adenine Nucleotides; Animals; Blood; Blood Flow Velocity; Brain; Calcium Channel Blockers; Carbon Dioxide; Cerebrovascular Circulation; Dogs; Glucose; Hydrogen-Ion Concentration; Ischemic Attack, Transient; Kinetics; Lactates; Lactic Acid; Nicotinic Acids; Nimodipine; Pyruvates; Pyruvic Acid; Vascular Resistance

1986
Nimodipine does not affect cerebral lactate levels following complete ischemia in dogs.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Dogs; Energy Metabolism; Female; Lactates; Lactic Acid; Male; Nimodipine

1987
Intracellular Ca2+ transients evoked by lactic acid in cultured mammalian neurons.
    The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 2

    Topics: Animals; Calcium; Cell Survival; Cells, Cultured; Cytosol; Hydrogen-Ion Concentration; Intracellular Membranes; Lactates; Lactic Acid; Membrane Potentials; Neurons; Nimodipine; Potassium; Rats

1995
Effect of lactate on the synaptic potential, energy metabolism, calcium homeostasis and extracellular glutamate concentration in the dentate gyrus of the hippocampus from guinea-pig.
    Neuroscience, 2001, Volume: 104, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Dentate Gyrus; Energy Metabolism; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycolysis; Guinea Pigs; Homeostasis; Intracellular Fluid; Lactic Acid; Neurons; Nimodipine; Organ Culture Techniques; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Theophylline

2001
Effects of nimodipine on tissue lactate and malondialdehyde levels in experimental head trauma.
    Anaesthesia and intensive care, 2001, Volume: 29, Issue:5

    Topics: Animals; Calcium Channel Blockers; Craniocerebral Trauma; Female; Lactic Acid; Male; Malondialdehyde; Nimodipine; Rabbits

2001
Nimodipine loaded PLGA nanoparticles: formulation optimization using factorial design, characterization and in vitro evaluation.
    Current drug delivery, 2007, Volume: 4, Issue:3

    Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Drug Carriers; Freeze Drying; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Models, Chemical; Nanoparticles; Nanotechnology; Nimodipine; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface-Active Agents; Vasospasm, Intracranial

2007
[Fabrication, characterization and drug release characteristics of drug loaded poly (L-lactic acid) fiber].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2008, Volume: 25, Issue:4

    Topics: Absorbable Implants; Delayed-Action Preparations; Drug Carriers; Drug Implants; Lactic Acid; Nimodipine; Polyesters; Polymers

2008
Local delivery of nimodipine by prolonged-release microparticles-feasibility, effectiveness and dose-finding in experimental subarachnoid hemorrhage.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Angiography, Digital Subtraction; Animals; Brain; Calcium-Binding Proteins; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Gene Expression; Immunohistochemistry; Injections, Intravenous; Lactic Acid; Male; Microfilament Proteins; Microtubule-Associated Proteins; Nimodipine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Subarachnoid Hemorrhage; Vasodilator Agents; Vasospasm, Intracranial

2012
Rational design of block copolymer micelles to control burst drug release at a nanoscale dimension.
    Acta biomaterialia, 2015, Volume: 24

    Topics: Drug Carriers; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Micelles; Nimodipine; Polyesters; Polyethylene Glycols; Polymers

2015
The application of novel nano-thermal and imaging techniques for monitoring drug microstructure and distribution within PLGA microspheres.
    International journal of pharmaceutics, 2017, Apr-30, Volume: 522, Issue:1-2

    Topics: Color; Drug Compounding; Lactic Acid; Microspheres; Nimodipine; Optical Imaging; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Surface Properties; Transition Temperature; X-Ray Diffraction

2017
ISSLS PRIZE in basic science 2023: Lactate in lumbar discs-metabolic waste or energy biofuel? Insights from in vivo MRS and T2r analysis following exercise and nimodipine in healthy volunteers.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2023, Volume: 32, Issue:5

    Topics: Awards and Prizes; Biofuels; Healthy Volunteers; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Lactic Acid; Lumbar Vertebrae; Magnetic Resonance Imaging; Nimodipine; Proteoglycans

2023