lactic acid and lysine

lactic acid has been researched along with lysine in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19907 (11.11)18.7374
1990's4 (6.35)18.2507
2000's19 (30.16)29.6817
2010's21 (33.33)24.3611
2020's12 (19.05)2.80

Authors

AuthorsStudies
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Berdanier, CD; Wander, RC1
Goldstein, WE1
Watson, TG1
Kümmel, L1
Baue, AE; Chaudry, IH; Clemens, MG; McDermott, PH1
Kanapka, JA; Kleinberg, I1
Arnold, RR; Brewer, M; Champion, WJ; Gauthier, JJ; Russell, JE1
Cannizzaro, SM; Cook, AD; Hrkach, JS; Langer, R; Pajvani, UB1
Boulat, O; Feihl, F; Gnaegi, A; Liaudet, L; Markert, M; Perret, C; Rosselet, A1
Beisswenger, P; Brownlee, M; Giardino, I; Onorato, J; Shinohara, M; Thornalley, PJ; Thorpe, SR1
Healy, VL; Lessard, IA; Park, IS; Walsh, CT1
Barton, JD; Beaudoin, I; Chapman, SK; Chen, ZW; Durley, RC; Lederer, F; Mathews, FS; Mowat, CG; Pike, AD; Reid, GA1
Anderson, SM; Hay, WW; Thureen, PJ1
Kondurkar, P; Muranjan, MN1
Benner, A; Breitkreutz, R; Dröge, W; Holm, E; Pittack, N; Rossol, S; Stein, J; Tokus, M; Wagner, J1
del Nido, PJ; McGowan, FX; Simplaceanu, E; Takeuchi, K; Tsushima, T1
Eisenschenk, S; McMahon, RJ; Rathman, SC1
Hollinger, JO; Hu, Y; Krajbich, I; Winn, SR1
Byun, Y; Jeong, JH; Park, TG1
Jung, GY; Koffas, MA; Stephanopoulos, G1
Blum, LJ; Degiuli, A; Marquette, CA; Thomas, D1
DeLuca, PP; Kim, WB; Lee, KC; Lee, SD; Na, DH; Son, MW; Youn, YS1
Blum, LJ; Degiuli, A; Marquette, CA1
Nicoli, S; Santi, P; Sebastiani, P1
Gygi, SP; Haas, W; Lerin, C; Puigserver, P; Rodgers, JT; Spiegelman, BM1
Bidner, TD; Guzik, AC; Lemieux, FM; Matthews, JO; Southern, LL1
Anderlei, T; Binder, M; Büchs, J; Zimmermann, HF1
Khew, ST; Lee, LY; Nie, H; Poh, KL; Tong, YW; Wang, CH1
Bao, Y; Jia, W; Qiu, Y; Su, M; Wang, X; Zhao, T1
Chen, Z; Liu, C; Yu, W; Zhang, N1
Takayama, T; Todo, M; Tsuji, H1
Heinzle, E; Neuner, A1
Chen, Z; Liu, C; Yu, W; Zhang, J; Zhang, N1
Ahmad, FJ; Ahmad, S; Ali, M; Anish, CK; Panda, AK; Parveen, R; Vasudev, SS1
Duan, Y; Li, Y; Liu, P; Qi, X; Sun, Y; Wang, H1
Deshpande, R; Kang, S; Miranda, LP; Mullen, J1
Cai, S; Chen, W; Ke, J; Li, X; Liu, B; Zhang, L; Zhang, Y1
Dai, H; Li, B; Li, S; Qiu, T; Wang, X; Xie, L; Yan, Q; Yin, Y1
Gong, A; Ma, X; Ren, W; Shen, Z; Wu, A; Xiang, L1
Chen, X; Cheng, Y; Gong, Y; He, C; Li, D; Liu, J; Ma, H; Tian, H1
Buettner, GR; Gius, D; Jung, B; Ozden, O; Park, SH; Song, HY; Vassilopoulos, A; Wagner, BA; Zhu, Y1
Chengdong, X; Lijuan, X; Liuyun, J; Lixin, J; Ye, L1
Amaral, AU; Cecatto, C; de Oliveira, FH; de Souza, DG; Goodman, S; Lagranha, VL; Pereira, CC; Ribeiro, CA; Seminotti, B; Wajner, M; Woontner, M1
Desguin, B; Hausinger, RP; Hols, P; Hu, J; Soumillion, P; Zhang, T1
Wang, K; Xing, Y; Yu, Q; Zhang, H1
García-Villoria, J; Girós, M; Ribes, A; Ruiz, A; Torres, MA; Tort, F; Ugarteburu, O1
Fan, Z; Jordan, P; Kettenmann, H; Meyer, N; Nolte, C; Pivneva, T; Richter, N; Semtner, M; Siemonsmeier, G; Steinhäuser, C1
Clark, RL; Korosh, TC; McGinley, LL; Pfleger, BF; Purdy, HM; Reed, JL; Root, TW1
Andrade, N; Correia-Branco, A; Ferreira, AC; Martel, F; Silva, C; Soares, ML; Sonveaux, P; Stephenne, J1
Becker, L; Cui, C; Czyz, D; Dai, L; Ding, J; He, M; Hu, R; Huang, H; Kim, S; Lee, S; Liu, W; Perez-Neut, M; Ren, B; Roeder, RG; Shuman, HA; Tang, Z; Weng, Y; Ye, Z; Zhang, D; Zhao, Y; Zheng, YG; Zhou, G1
Chen, M; Hou, GF; Jin, YX; OuYang, YN; Tian, Z; Yang, PF; Zhou, LX1
Biernat, M; Gazińska, M; Grzymajło, M; Jóźwiak, P; Michlewska, S; Płociński, P; Rudnicka, K; Sieja, K; Szustakiewicz, K; Szymczyk-Ziółkowska, P; Trochimczuk, AW; Włodarczyk, M; Ziółkowski, G1
Hagihara, H; Katoh, K; Miyakawa, T; Namihira, M; Otabi, H; Shoji, H; Toyoda, A1
Chen, F; Cheng, KW; Cheng, W; Wang, M; Wang, X; Zhang, Z1
Chen, Y; Gong, T; Huang, J; Li, Y; Liu, Y; Ma, Q; Pan, Y; Sun, Q; Yu, S; Zhang, Q; Zou, J1
Cang, W; Chen, L; Gu, Y; Huang, L; Sun, P; Xiang, Y1
Mao, L; Wang, J; Wang, JH; Wen, Q; Wu, M; Yu, SC; Zhang, X1
Kong, J; Liu, JF; Wang, QC; Yang, JT; Yang, YH1
Cheng, X; Feng, Y; Jia, M; Sun, W1
Gong, T; Li, Y; Li, Z; Peng, X; Ren, B; Wu, Q; Zhang, Y; Zheng, X; Zhou, X1
Li, X; Liu, Q; Long, M; Wu, Q; Xie, X1
Deng, J; Liao, X1

Reviews

4 review(s) available for lactic acid and lysine

ArticleYear
Economics of immobilized biocatalyst processes.
    Annals of the New York Academy of Sciences, 1987, Volume: 506

    Topics: Biotechnology; Catalysis; Culture Media; Fermentation; Lactates; Lactic Acid; Lysine

1987
Lactate-Lactylation Hands between Metabolic Reprogramming and Immunosuppression.
    International journal of molecular sciences, 2022, Oct-08, Volume: 23, Issue:19

    Topics: Histones; Humans; Immunologic Deficiency Syndromes; Immunosuppression Therapy; Lactic Acid; Lysine; Neoplasms; Tumor Microenvironment; Waste Products

2022
Beyond metabolic waste: lysine lactylation and its potential roles in cancer progression and cell fate determination.
    Cellular oncology (Dordrecht), 2023, Volume: 46, Issue:3

    Topics: Epigenesis, Genetic; Glycolysis; Humans; Lactic Acid; Lysine; Neoplasms

2023
Lysine lactylation regulates metabolic pathways and biofilm formation in
    Science signaling, 2023, 09-05, Volume: 16, Issue:801

    Topics: Biofilms; Glycolysis; Lactic Acid; Lysine; Streptococcus mutans; Sugars

2023

Other Studies

59 other study(ies) available for lactic acid and lysine

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Effects of type of dietary fat and carbohydrate on gluconeogenesis in isolated hepatocytes from BHE rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:7

    Topics: Animals; Coconut Oil; Corn Oil; Dietary Carbohydrates; Dietary Fats; Gluconeogenesis; Lactates; Lactic Acid; Linoleic Acid; Linoleic Acids; Liver; Lysine; Male; Oils; Palmitic Acid; Palmitic Acids; Plant Oils; Pyruvates; Pyruvic Acid; Rats; Rats, Mutant Strains; Starch; Sucrose

1986
Effect of carbon source on lysine-mediated inhibition of postexponential growth of Saccharomyces cerevisiae.
    Journal of bacteriology, 1983, Volume: 154, Issue:2

    Topics: Arginine; Culture Media; Glucose; Lactates; Lactic Acid; Lysine; Saccharomyces cerevisiae

1983
Combined effect of lysine and acetate on gluconeogenesis from lactate in isolated hepatocytes.
    Physiologia Bohemoslovaca, 1983, Volume: 32, Issue:1

    Topics: Acetates; Animals; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Liver; Lysine; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1983
Regulation of glucose production from lactate in experimental sepsis.
    The American journal of physiology, 1983, Volume: 244, Issue:6

    Topics: Adenosine Triphosphate; Animals; Gluconeogenesis; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Liver; Lysine; Male; Oxygen Consumption; Perfusion; Phenylephrine; Rats; Sepsis

1983
Catabolism of arginine by the mixed bacteria in human salivary sediment under conditions of low and high glucose concentration.
    Archives of oral biology, 1983, Volume: 28, Issue:11

    Topics: Ammonia; Arginine; Autoradiography; Bacteria; Cadaverine; Carbon Dioxide; Glucose; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Lysine; Putrescine; Saliva

1983
Bactericidal activity of human lactoferrin: differentiation from the stasis of iron deprivation.
    Infection and immunity, 1982, Volume: 35, Issue:3

    Topics: Glucose; Humans; Iron; Lactates; Lactic Acid; Lactoferrin; Lactoglobulins; Lysine; Streptococcus mutans; Thymidine; Uracil

1982
Colorimetric analysis of surface reactive amino groups on poly(lactic acid-co-lysine):poly(lactic acid) blends.
    Biomaterials, 1997, Volume: 18, Issue:21

    Topics: Amino Acids; Colorimetry; Lactic Acid; Lysine; Polyesters; Polylysine; Polymers; Prostheses and Implants

1997
Effect of L-lysine on nitric oxide overproduction in endotoxic shock.
    British journal of pharmacology, 1997, Volume: 122, Issue:4

    Topics: Animals; Hematocrit; Hemodynamics; Lactic Acid; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Shock, Septic

1997
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
    The Journal of clinical investigation, 1998, Mar-01, Volume: 101, Issue:5

    Topics: Acetone; Aldehydes; Animals; Cattle; Endocytosis; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Glycation End Products, Advanced; Glyoxal; Hyperglycemia; Ketones; Lactic Acid; Lactoylglutathione Lyase; Lysine; Pyruvaldehyde; Transfection; Tumor Cells, Cultured

1998
Determinants for differential effects on D-Ala-D-lactate vs D-Ala-D-Ala formation by the VanA ligase from vancomycin-resistant enterococci.
    Biochemistry, 1999, Oct-19, Volume: 38, Issue:42

    Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Arginine; Bacterial Proteins; Base Sequence; Carbon-Oxygen Ligases; Dipeptides; Enterococcus; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Lactic Acid; Leuconostoc; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Synthases; Stereoisomerism; Templates, Genetic; Vancomycin; Vancomycin Resistance

1999
Kinetic and crystallographic studies on the active site Arg289Lys mutant of flavocytochrome b2 (yeast L-lactate dehydrogenase).
    Biochemistry, 2000, Mar-28, Volume: 39, Issue:12

    Topics: Arginine; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Kinetics; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; Lysine; Mandelic Acids; Mutagenesis, Site-Directed; Oxalates; Pyruvates; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Sulfites

2000
Regulation of uterine and umbilical amino acid uptakes by maternal amino acid concentrations.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:3

    Topics: Amino Acids; Animals; Blood Glucose; Female; Gestational Age; Glucose Clamp Technique; Hyperglycemia; Insulin; Lactic Acid; Leucine; Lysine; Maternal-Fetal Exchange; Ornithine; Oxygen; Placenta; Pregnancy; Sheep; Umbilical Cord; Uterus

2000
Clinical features of organic acidemias: experience at a tertiary care center in Mumbai.
    Indian pediatrics, 2001, Volume: 38, Issue:5

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Amino Acids, Dicarboxylic; Developing Countries; Humans; India; Lactic Acid; Lysine; Retrospective Studies

2001
Flux of amino acids and energy substrates across the leg in weight-stable HIV-infected patients with acute opportunistic infections: indication of a slow protein wasting process.
    Journal of molecular medicine (Berlin, Germany), 2001, Volume: 79, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Amino Acids; Arginine; Blood Glucose; Case-Control Studies; Dose-Response Relationship, Drug; Erythrocytes; Fatty Acids; Female; Glycerol; HIV Seropositivity; HIV Wasting Syndrome; Humans; Insulin; Interleukin-6; Ketones; Lactic Acid; Leg; Lysine; Male; Middle Aged; Muscle, Skeletal; Nitrogen; Pyruvic Acid

2001
L-arginine potentiates negative inotropic and metabolic effects to myocardium partly through the amiloride sensitive mechanism.
    The Japanese journal of physiology, 2002, Volume: 52, Issue:2

    Topics: Adenosine Triphosphate; Amiloride; Animals; Arginine; Blood Pressure; Caustics; Diuretics; Drug Synergism; Energy Metabolism; Glucose; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Lysine; Myocardial Contraction; Myocardium; Nitric Oxide; Oxygen Consumption; Perfusion; Rabbits; Sodium Hydroxide; Sodium-Hydrogen Exchangers

2002
The abundance and function of biotin-dependent enzymes are reduced in rats chronically administered carbamazepine.
    The Journal of nutrition, 2002, Volume: 132, Issue:11

    Topics: Acetyl-CoA Carboxylase; Ammonia; Animals; Anticonvulsants; Biotin; Biotinylation; Brain; Carbamazepine; Carbon-Carbon Ligases; Diet; Drug Interactions; Lactic Acid; Liver; Lysine; Male; Pyruvate Carboxylase; Rats; Rats, Sprague-Dawley

2002
Porous polymer scaffolds surface-modified with arginine-glycine-aspartic acid enhance bone cell attachment and differentiation in vitro.
    Journal of biomedical materials research. Part A, 2003, Mar-01, Volume: 64, Issue:3

    Topics: Absorbable Implants; Alkaline Phosphatase; Biocompatible Materials; Calcium; Cell Adhesion; Cell Culture Techniques; Cell Differentiation; Cell Division; Cells, Cultured; Humans; Lactic Acid; Lysine; Materials Testing; Oligopeptides; Osteoblasts; Polyesters; Polymers; Porosity; Stem Cells; Surface Properties

2003
Synthesis and characterization of poly(L-lysine)-g-poly(D,L-lactic-co-glycolic acid) biodegradable micelles.
    Journal of biomaterials science. Polymer edition, 2003, Volume: 14, Issue:1

    Topics: Biocompatible Materials; Biodegradation, Environmental; Lactic Acid; Lysine; Micelles; Microscopy, Atomic Force; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polylysine; Polymers; Proteins; Spectrum Analysis

2003
Engineering metabolism and product formation in Corynebacterium glutamicum by coordinated gene overexpression.
    Metabolic engineering, 2003, Volume: 5, Issue:1

    Topics: Aspartate Kinase; Cloning, Molecular; Coenzymes; Corynebacterium; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Lactic Acid; Lysine; Protein Engineering; Pyruvate Carboxylase; Recombinant Proteins; Species Specificity

2003
Design of luminescent biochips based on enzyme, antibody, or DNA composite layers.
    Analytical and bioanalytical chemistry, 2003, Volume: 377, Issue:5

    Topics: Antibodies; Biosensing Techniques; Choline; DNA; Enzymes; Glucose; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Luminescent Measurements; Lysine; Uric Acid

2003
Monitoring of peptide acylation inside degrading PLGA microspheres by capillary electrophoresis and MALDI-TOF mass spectrometry.
    Journal of controlled release : official journal of the Controlled Release Society, 2003, Oct-30, Volume: 92, Issue:3

    Topics: Acylation; Amino Acid Sequence; Animals; Calcitonin; Drug Carriers; Electrophoresis, Capillary; Glycolates; Humans; Lactic Acid; Leuprolide; Lysine; Microspheres; Molecular Sequence Data; Parathyroid Hormone; Peptide Hormones; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Salmon; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2003
Electrochemiluminescent biosensors array for the concomitant detection of choline, glucose, glutamate, lactate, lysine and urate.
    Biosensors & bioelectronics, 2003, Dec-30, Volume: 19, Issue:5

    Topics: Biosensing Techniques; Choline; Complex Mixtures; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Glucose; Glutamic Acid; Lactic Acid; Luminescent Measurements; Lysine; Oxidoreductases; Protein Array Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Uric Acid

2003
Effect of lactic acid and iontophoresis on drug permeation across rabbit ear skin.
    International journal of pharmaceutics, 2005, Mar-23, Volume: 292, Issue:1-2

    Topics: Acetaminophen; Administration, Topical; Animals; Biological Availability; Buspirone; Cell Membrane Permeability; Drug Evaluation, Preclinical; Ear; Excipients; Ibuprofen; Iontophoresis; Lactic Acid; Lysine; Rabbits; Skin Absorption

2005
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
    Nature, 2005, Mar-03, Volume: 434, Issue:7029

    Topics: Acetylation; Animals; Caloric Restriction; Cyclic AMP; Fasting; Gene Expression Regulation; Gluconeogenesis; Glucose; Glycolysis; Hepatocytes; Homeostasis; Insulin; Lactic Acid; Liver; Longevity; Lysine; Mice; NAD; Nutritional Status; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Binding; Pyruvic Acid; Rats; RNA, Messenger; Sirtuin 1; Sirtuins; Trans-Activators; Transcription Factors

2005
Effects of chromium propionate on growth, carcass traits, and pork quality of growing-finishing pigs.
    Journal of animal science, 2005, Volume: 83, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Diet; Female; Food Handling; Hydrocortisone; Lactic Acid; Lysine; Meat; Propionates; Swine

2005
Oxygen limitation is a pitfall during screening for industrial strains.
    Applied microbiology and biotechnology, 2006, Volume: 72, Issue:6

    Topics: Acetic Acid; Biomass; Bioreactors; Corynebacterium glutamicum; Densitometry; Industrial Microbiology; Lactic Acid; Lysine; Oxygen Consumption; Statistics as Topic; Succinic Acid

2006
Lysine-based peptide-functionalized PLGA foams for controlled DNA delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Aug-19, Volume: 138, Issue:1

    Topics: Adsorption; Animals; Bone Marrow Cells; Bone Morphogenetic Protein 2; Cell Survival; Cells, Cultured; Delayed-Action Preparations; DNA; Gene Expression; Lactic Acid; Lysine; Peptides; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats; Spectrometry, X-Ray Emission; Static Electricity; Surface Properties; Transfection

2009
Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers.
    Journal of proteome research, 2009, Volume: 8, Issue:4

    Topics: Carbamates; Diabetes Mellitus, Type 2; Gas Chromatography-Mass Spectrometry; Humans; Hypoglycemic Agents; Lactic Acid; Lysine; Metabolomics; Metformin; Piperidines; Rosiglitazone; Thiazolidinediones; Uric Acid; Valine

2009
Novel cationic 6-lauroxyhexyl lysinate modified poly(lactic acid)-poly(ethylene glycol) nanoparticles enhance gene transfection.
    Journal of colloid and interface science, 2011, Feb-15, Volume: 354, Issue:2

    Topics: Cell Survival; Deoxyribonucleases; DNA; Hep G2 Cells; Humans; Lactic Acid; Laurates; Lysine; Nanoparticles; Polyesters; Polyethylene Glycols; Polymers; Surface-Active Agents; Transfection

2011
Effect of annealing on the mechanical properties of PLA/PCL and PLA/PCL/LTI polymer blends.
    Journal of the mechanical behavior of biomedical materials, 2011, Volume: 4, Issue:3

    Topics: Elastic Modulus; Isocyanates; Lactic Acid; Lysine; Mechanical Phenomena; Microscopy, Electron, Scanning; Polyesters; Polymers; Surface Properties

2011
Mixed glucose and lactate uptake by Corynebacterium glutamicum through metabolic engineering.
    Biotechnology journal, 2011, Volume: 6, Issue:3

    Topics: Corynebacterium glutamicum; Genetic Engineering; Glucose; Glucose-6-Phosphate Isomerase; Lactate Dehydrogenases; Lactic Acid; Lysine; Malate Dehydrogenase; Metabolic Networks and Pathways; Promoter Regions, Genetic; Pyruvate Carboxylase

2011
cNGR conjugated poly(lactic acid)-poly(ethylene glycol) nanoparticles for targeted gene delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Caveolae; CD13 Antigens; DNA; Endocytosis; Flow Cytometry; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Laurates; Liver Neoplasms; Lysine; Magnetic Resonance Spectroscopy; Microscopy, Fluorescence; Nanoparticles; Nanotechnology; Nucleic Acid Conformation; Peptides, Cyclic; Polyesters; Polyethylene Glycols; Polymers; Surface-Active Agents; Transfection

2011
Formulation of PEG-ylated L-asparaginase loaded poly (lactide-co-glycolide) nanoparticles: influence of Pegylation on enzyme loading, activity and in vitro release.
    Die Pharmazie, 2011, Volume: 66, Issue:12

    Topics: Asparaginase; Chromatography, Gel; Chromatography, High Pressure Liquid; Computer Simulation; Drug Compounding; Drug Delivery Systems; Electrophoresis, Polyacrylamide Gel; Emulsions; Lactic Acid; Lysine; Microscopy, Electron, Scanning; Molecular Weight; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rheology; Solvents; Ultrasonics

2011
RGD-conjugated PLA-PLL nanoparticles targeting to Bacp-37 breast cancer xenografts in vivo.
    Journal of nanoscience and nanotechnology, 2011, Volume: 11, Issue:12

    Topics: Biocompatible Materials; Breast Neoplasms; Female; Flow Cytometry; Humans; Lactic Acid; Lysine; Microscopy, Confocal; Nanoparticles; Oligopeptides; Polyesters; Polymers; Tissue Distribution; Xenograft Model Antitumor Assays

2011
Utilization of tyrosine- and histidine-containing dipeptides to enhance productivity and culture viability.
    Biotechnology and bioengineering, 2012, Volume: 109, Issue:9

    Topics: Animals; Bioreactors; Biotechnology; Cell Culture Techniques; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Culture Media; Dipeptides; Histidine; Hydrogen-Ion Concentration; Lactic Acid; Lysine; Tyrosine

2012
[Analysis of an acellular pigskin based nerve scaffold].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2012, Volume: 28, Issue:3

    Topics: Acellular Dermis; Animals; Biocompatible Materials; Guided Tissue Regeneration; Lactic Acid; Lysine; Nerve Growth Factors; Nerve Regeneration; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Swine; Tissue Engineering; Tissue Scaffolds

2012
PDLLA/PRGD/β-TCP conduits build the neurotrophin-rich microenvironment suppressing the oxidative stress and promoting the sciatic nerve regeneration.
    Journal of biomedical materials research. Part A, 2014, Volume: 102, Issue:10

    Topics: Animals; Calcium Phosphates; Cellular Microenvironment; Gene Expression Regulation; Guided Tissue Regeneration; Lactic Acid; Lysine; Nerve Growth Factor; Nerve Regeneration; Oxidative Stress; Polyesters; Polymers; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sciatic Nerve

2014
Improved double emulsion technology for fabricating autofluorescent microcapsules as novel ultrasonic/fluorescent dual-modality contrast agents.
    Colloids and surfaces. B, Biointerfaces, 2014, Apr-01, Volume: 116

    Topics: Biocompatible Materials; Capsules; Cell Survival; Contrast Media; Emulsions; Fluorescence; Glutaral; Humans; Lactic Acid; Lysine; MCF-7 Cells; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Tumor Cells, Cultured; Ultrasonics

2014
PLK1shRNA and doxorubicin co-loaded thermosensitive PLGA-PEG-PLGA hydrogels for osteosarcoma treatment.
    Biomaterials, 2014, Volume: 35, Issue:30

    Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line; Cell Survival; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Hydrogels; In Situ Nick-End Labeling; Lactic Acid; Lysine; Male; Mice, Nude; Osteosarcoma; Phase Transition; Polo-Like Kinase 1; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats, Wistar; RNA, Small Interfering; Solutions; Tissue Distribution; Transfection

2014
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.
    Free radical biology & medicine, 2014, Volume: 76

    Topics: Acetylation; Blotting, Western; Cell Proliferation; Fluorescent Antibody Technique; Glucose; Glycolysis; Humans; Immunoprecipitation; Lactic Acid; Lysine; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Phenotype; Protein Processing, Post-Translational; Pyruvate Dehydrogenase (Lipoamide); Pyruvic Acid; Reactive Oxygen Species; Sirtuin 3; Tumor Cells, Cultured

2014
Effect of l-lysine-assisted surface grafting for nano-hydroxyapatite on mechanical properties and in vitro bioactivity of poly(lactic acid-co-glycolic acid).
    Journal of biomaterials applications, 2016, Volume: 30, Issue:6

    Topics: Bone Substitutes; Cell Adhesion; Cell Line; Cell Proliferation; Cell Survival; Coated Materials, Biocompatible; Compressive Strength; Durapatite; Elastic Modulus; Hardness; Humans; Lactic Acid; Lysine; Materials Testing; Nanoparticles; Osteoblasts; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stress, Mechanical; Surface Properties; Tensile Strength; Thermal Conductivity

2016
Experimental evidence that bioenergetics disruption is not mainly involved in the brain injury of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload.
    Brain research, 2015, Sep-16, Volume: 1620

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases; Brain Diseases, Metabolic; Cerebral Cortex; Corpus Striatum; Diet; Disease Models, Animal; Energy Metabolism; Glutaryl-CoA Dehydrogenase; Isocitrate Dehydrogenase; Lactic Acid; Lysine; Membrane Potential, Mitochondrial; Mice, 129 Strain; Mice, Knockout; Oxygen Consumption

2015
METALLOPROTEINS. A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase.
    Science (New York, N.Y.), 2015, Jul-03, Volume: 349, Issue:6243

    Topics: Bacterial Proteins; Binding Sites; Carbon; Catalysis; Crystallography, X-Ray; Histidine; Holoenzymes; Lactic Acid; Lactobacillus plantarum; Ligands; Lysine; Metalloproteins; Niacin; Nickel; Nicotinamide Mononucleotide; Protein Processing, Post-Translational; Protein Structure, Secondary; Racemases and Epimerases; Spectrometry, Mass, Electrospray Ionization; Sulfur

2015
Lysine-doped polypyrrole/spider silk protein/poly(l-lactic) acid containing nerve growth factor composite fibers for neural application.
    Materials science & engineering. C, Materials for biological applications, 2015, Nov-01, Volume: 56

    Topics: Animals; Axons; Lactic Acid; Lysine; Male; Nanofibers; Nerve Growth Factor; Nerve Regeneration; Neurites; PC12 Cells; Polyesters; Polymers; Pyrroles; Rats; Rats, Wistar; Schwann Cells; Silk; Spiders; Tissue Scaffolds

2015
Lysine Restriction and Pyridoxal Phosphate Administration in a NADK2 Patient.
    Pediatrics, 2016, Volume: 138, Issue:5

    Topics: Child; Diet; Epilepsies, Myoclonic; Female; Homozygote; Humans; Hyperlysinemias; Lactic Acid; Lysine; Mitochondrial Diseases; Mitochondrial Proteins; Mutation; Nervous System Malformations; Phosphotransferases (Alcohol Group Acceptor); Pipecolic Acids; Pyridoxal Phosphate; RNA, Messenger; Vitamin B Complex

2016
Oligodendrocytes in the Mouse Corpus Callosum Maintain Axonal Function by Delivery of Glucose.
    Cell reports, 2018, 02-27, Volume: 22, Issue:9

    Topics: Action Potentials; Animals; Astrocytes; Axons; Connexins; Corpus Callosum; Dialysis; Glucose; Lactic Acid; Lysine; Mice, Knockout; Monocarboxylic Acid Transporters; Neuroglia; Oligodendroglia; Pyruvic Acid

2018
Light-optimized growth of cyanobacterial cultures: Growth phases and productivity of biomass and secreted molecules in light-limited batch growth.
    Metabolic engineering, 2018, Volume: 47

    Topics: Biomass; Bioreactors; Lactic Acid; Light; Lysine; Metabolic Engineering; Synechococcus

2018
Selective pro-apoptotic and antimigratory effects of polyphenol complex catechin:lysine 1:2 in breast, pancreatic and colorectal cancer cell lines.
    European journal of pharmacology, 2019, Sep-15, Volume: 859

    Topics: Antineoplastic Agents; Apoptosis; Biological Transport; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Glucose; Humans; Lactic Acid; Lysine; Pancreatic Neoplasms; Polyphenols

2019
Metabolic regulation of gene expression by histone lactylation.
    Nature, 2019, Volume: 574, Issue:7779

    Topics: Acetylation; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Epigenesis, Genetic; Glycolysis; Histones; Homeostasis; Humans; Hypoxia; Lactic Acid; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Reproducibility of Results; Transcription, Genetic

2019
Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for hypercholesterolemia.
    Biochemical and biophysical research communications, 2021, 05-14, Volume: 553

    Topics: Adolescent; Adult; Arginine; Biomarkers; Case-Control Studies; Cholesterol; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Humans; Hypercholesterolemia; Lactic Acid; Lysine; Male; Metabolomics; Methionine; Middle Aged; Phosphoric Acids; Urea; Young Adult

2021
The Effect of Pore Size Distribution and l-Lysine Modified Apatite Whiskers (HAP) on Osteoblasts Response in PLLA/HAP Foam Scaffolds Obtained in the Thermally Induced Phase Separation Process.
    International journal of molecular sciences, 2021, Mar-30, Volume: 22, Issue:7

    Topics: Apatites; Biocompatible Materials; Cell Line, Tumor; Durapatite; Humans; Lactic Acid; Lysine; Osteoblasts; Polyesters; Polymers; Porosity; Tissue Engineering; Tissue Scaffolds

2021
Protein lactylation induced by neural excitation.
    Cell reports, 2021, 10-12, Volume: 37, Issue:2

    Topics: Action Potentials; Animals; Anxiety; Behavior, Animal; Brain; Cells, Cultured; Histones; Lactic Acid; Lysine; Mice, Inbred C57BL; Mice, Inbred ICR; Neurons; Protein Processing, Post-Translational; Proteome; Proto-Oncogene Proteins c-fos; Social Defeat

2021
A novel formation pathway of N
    Food chemistry, 2022, Sep-15, Volume: 388

    Topics: Bread; Glycation End Products, Advanced; Lactic Acid; Lysine; Models, Chemical; Temperature; Triticum

2022
Acetylation of Lactate Dehydrogenase Negatively Regulates the Acidogenicity of Streptococcus mutans.
    mBio, 2022, 10-26, Volume: 13, Issue:5

    Topics: Acetylation; Acetyltransferases; Animals; Dental Caries; L-Lactate Dehydrogenase; Lactic Acid; Lysine; Protein Processing, Post-Translational; Pyruvates; Rats; Streptococcus mutans; Virulence Factors

2022
Global profiling of lysine lactylation in human lungs.
    Proteomics, 2023, Volume: 23, Issue:15

    Topics: Chromatography, Liquid; Humans; Lactic Acid; Lung; Lysine; Tandem Mass Spectrometry

2023
Lactate is a bridge linking glycolysis and autophagy through lactylation.
    Autophagy, 2023, Volume: 19, Issue:12

    Topics: Autophagy; Autophagy-Related Proteins; Beclin-1; Class III Phosphatidylinositol 3-Kinases; Glycolysis; Lactic Acid; Lysine

2023
Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular carcinoma.
    Scientific reports, 2023, 10-30, Volume: 13, Issue:1

    Topics: Carcinoma, Hepatocellular; Histones; Humans; Lactic Acid; Liver Neoplasms; Lysine; Nuclear Receptor Subfamily 6, Group A, Member 1; Prognosis; Tumor Microenvironment

2023
Lysine lactylation (Kla) might be a novel therapeutic target for breast cancer.
    BMC medical genomics, 2023, 11-10, Volume: 16, Issue:1

    Topics: Breast Neoplasms; Female; Histones; Humans; Immunotherapy; Lactic Acid; Lysine; Neoplasms; Prognosis; Tumor Microenvironment

2023