lactic acid and isoniazid

lactic acid has been researched along with isoniazid in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.03)	18.7374
1990's	6 (18.18)	18.2507
2000's	10 (30.30)	29.6817
2010's	16 (48.48)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Ashtekar, DR; Farhi, DC; Gangadharam, PR; Wise, DL	1
Daneluzzi, D; Gangadharam, PR; Kailasam, S	1
Gangadharam, PR; Kailasam, S; Srinivasan, S; Wise, DL	1
Gangadharam, PR; Gresser, JD; Hsu, YY; Lyons, CM; Simons, GA; Stewart, RR; Trantolo, DJ; Wise, DL	1
Gangadharam, PR; Gresser, JD; Hsu, YY; Lyons, CM; Trantolo, DJ; Wise, DL	1
Gangadharam, PR; Geeta, N; Hsu, YY; Wise, DL	1
Dutt, M; Khuller, GK	4
Ain, Q; Garg, SK; Khuller, GK; Sharma, S	1
Khuller, GK; Sharma, S; Ul-Ain, Q	1
KRULIK, R	1
Khuller, GK; Pandey, R; Prasad, B; Sharma, A; Sharma, S; Zahoor, A	1
Khuller, GK; Pandey, R; Sharma, S; Zahoor, A	1
Khuller, GK; Pandey, R	1
Choonara, YE; du Toit, LC; Jarvis, DL; Khan, RA; Kumar, P; Murphy, CS; Ndesendo, VM; Pillay, V	1
Báfica, A; Bechtold, IH; De Almeida, MV; de Assis, JV; de Faria, TJ; de Souza, NM; De Vecchi, R; dos Santos, AL; Roman, M; Silva, LP; Soares, MJ; Winter, N	1
Hamman, JH; Hayeshi, R; Hillie, TK; Kalombo, L; Naicker, B; Nkabinde, LA; Semete-Makokotlela, B; Shoba-Zikhali, LN; Swai, HS	1
Booysen, LL; Brooks, E; du Plessis, LH; Gilliland, J; Gruppo, V; Hansen, R; Kalombo, L; Kotze, AF; Lenaerts, A; Lungenhofer, P; Semete-Makokotlela, B; Swai, HS	1
Chawla, R; Jaiswal, S; Mishra, B	1
Hu, Z; Li, J; Wu, G; Wu, W; Zheng, Q; Zhou, J	1
Cao, X; Wei, K; Wei, X; Xu, W; Zhong, S	1
Bacsa, B; Balka, G; Bősze, S; Fodor, K; Gyulai, G; Horváti, K; Hudecz, F; Kiss, E; Rusvai, M; Szabó, E	1
Jiang, H; Jiang, J; Li, S; Lin, Z; Liu, P	1
Hussain, T; Moin, A; Nagshubha, B; Raizaday, A	1
Attalla, SM; Carter, WG; Christie, D; Elmorsy, E; Fikry, E; Kocon, A; Nwidu, LL; Turner, R; Warren, A	1
Li, D; Li, L; Ma, Y; Shen, H; Wang, X; Wu, D; Yang, F; Zhuang, Y	1
Wu, G; Wu, WG; Zheng, QX; Zhou, JB	1
Abbasova, K; Anshakova, A; Baklaushev, V; Balabanyan, V; Chekhonin, V; Gelperina, S; Kreuter, J; Maksimenko, O; Malinovskaya, J; Melnikov, P; Titov, S; Zybina, A	1
Bairy, I; Gaonkar, SL; Guru, BR; Hakkimane, SS; Shenoy, VP	1

Other Studies

33 other study(ies) available for lactic acid and isoniazid

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Sustained release of isoniazid in vivo from a single implant of a biodegradable polymer. Tubercle, 1991, Volume: 72, Issue:2 Topics: Biocompatible Materials; Delayed-Action Preparations; Drug Implants; Humans; Isoniazid; Lactic Acid; Liver; Lung; Mycobacterium tuberculosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tuberculosis	1991
Maintenance of therapeutically active levels of isoniazid for prolonged periods in rabbits after a single implant of biodegradable polymer. Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1994, Volume: 75, Issue:5 Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Isoniazid; Lactic Acid; Mycobacterium tuberculosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits	1994
Experimental chemotherapy of tuberculosis using single dose treatment with isoniazid in biodegradable polymers. The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:2 Topics: Animals; Biological Availability; Drug Carriers; Drug Implants; Isoniazid; Lactic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tuberculosis	1994
Mechanisms of isoniazid release from poly(d,l-lactide-co-glycolide) matrices prepared by dry-mixing and low density polymeric foam methods. Journal of pharmaceutical sciences, 1996, Volume: 85, Issue:7 Topics: Antitubercular Agents; Diffusion; Drug Carriers; Isoniazid; Lactic Acid; Microscopy, Electron, Scanning; Models, Chemical; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Temperature; Thermodynamics	1996
Effect of polymer foam morphology and density on kinetics of in vitro controlled release of isoniazid from compressed foam matrices. Journal of biomedical materials research, 1997, Volume: 35, Issue:1 Topics: Antitubercular Agents; Biocompatible Materials; Delayed-Action Preparations; Drug Delivery Systems; Fumarates; In Vitro Techniques; Isoniazid; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polypropylenes; Solubility	1997
Chemotherapy of tuberculosis in mice using single implants of isoniazid and pyrazinamide. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 1999, Volume: 3, Issue:6 Topics: Administration, Oral; Analysis of Variance; Animals; Antitubercular Agents; Biocompatible Materials; Biological Availability; Delayed-Action Preparations; Disease Models, Animal; Drug Administration Schedule; Drug Implants; Isoniazid; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Sensitivity and Specificity; Tuberculosis	1999
Therapeutic efficacy of Poly(DL-lactide-Co-Glycolide)-encapsulated antitubercular drugs against Mycobacterium tuberculosis infection induced in mice. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:1 Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Biocompatible Materials; Drug Combinations; Drug Compounding; Isoniazid; Lactic Acid; Mice; Mycobacterium tuberculosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Tissue Distribution; Tuberculosis	2001
Sustained release of isoniazid from a single injectable dose of poly (DL-lactide-co-glycolide) microparticles as a therapeutic approach towards tuberculosis. International journal of antimicrobial agents, 2001, Volume: 17, Issue:2 Topics: Animals; Antitubercular Agents; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Isoniazid; Lactic Acid; Liver; Lung; Male; Mice; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Spleen; Tuberculosis	2001
Chemotherapy of Mycobacterium tuberculosis infections in mice with a combination of isoniazid and rifampicin entrapped in Poly (DL-lactide-co-glycolide) microparticles. The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:6 Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Capsules; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Therapy, Combination; Female; Isoniazid; Lactic Acid; Male; Mice; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Treatment Outcome; Tuberculosis	2001
Liposomes and PLG microparticles as sustained release antitubercular drug carriers--an in vitro-in vivo study. International journal of antimicrobial agents, 2001, Volume: 18, Issue:3 Topics: Alkaline Phosphatase; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Aspartate Aminotransferases; Bilirubin; Delayed-Action Preparations; Drug Carriers; Female; Isoniazid; Lactic Acid; Liposomes; Liver; Male; Mice; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rifampin; Tissue Distribution	2001
Role of poly [DL-lactide-co-glycolide] in development of a sustained oral delivery system for antitubercular drug(s). International journal of pharmaceutics, 2002, Jun-04, Volume: 239, Issue:1-2 Topics: Administration, Oral; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biocompatible Materials; Capsules; Delayed-Action Preparations; Drug Compounding; Female; Half-Life; Isoniazid; Lactic Acid; Male; Mice; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Solubility	2002
Chemotherapeutic potential of orally administered poly(lactide-co-glycolide) microparticles containing isoniazid, rifampin, and pyrazinamide against experimental tuberculosis. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:9 Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biocompatible Materials; Biological Availability; Capsules; Drug Combinations; Drug Compounding; Isoniazid; Lactic Acid; Mice; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Tissue Distribution; Tuberculosis, Pulmonary	2003
[The effect of isoniazid on glycide matabolism. VI. Concentration of lactic acid in the rat liver after administration of isoniazid and gydrazine sulfate]. Beitrage zur Klinik der Tuberkulose und spezifischen Tuberkulose-Forschung, 1962, Volume: 126 Topics: Animals; Epoxy Compounds; Hydrazines; Isoniazid; Lactates; Lactic Acid; Liver; Propanols; Rats; Sulfates	1962
Poly (DL-lactide-co-glycolide) nanoparticle-based inhalable sustained drug delivery system for experimental tuberculosis. The Journal of antimicrobial chemotherapy, 2003, Volume: 52, Issue:6 Topics: Administration, Inhalation; Aerosols; Animals; Antibiotics, Antitubercular; Antitubercular Agents; Area Under Curve; Biological Availability; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry, Physical; Colony Count, Microbial; Drug Carriers; Drug Combinations; Drug Compounding; Female; Guinea Pigs; Half-Life; Injections, Intravenous; Isoniazid; Lactic Acid; Lung; Male; Microspheres; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Tuberculosis	2003
Nanoparticle encapsulated antitubercular drugs as a potential oral drug delivery system against murine tuberculosis. Tuberculosis (Edinburgh, Scotland), 2003, Volume: 83, Issue:6 Topics: Administration, Oral; Animals; Antitubercular Agents; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Glycolates; Isoniazid; Lactic Acid; Liver; Lung; Male; Mice; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazinamide; Rifampin; Spleen; Tuberculosis	2003
Subcutaneous nanoparticle-based antitubercular chemotherapy in an experimental model. The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:1 Topics: Animals; Antibiotics, Antitubercular; Antitubercular Agents; Biological Availability; Drug Combinations; Drug Compounding; Injections, Subcutaneous; Isoniazid; Lactic Acid; Lung; Mice; Microspheres; Mycobacterium tuberculosis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazinamide; Rifampin; Spleen; Tissue Distribution; Tuberculosis	2004
Polymeric emulsion and crosslink-mediated synthesis of super-stable nanoparticles as sustained-release anti-tuberculosis drug carriers. Colloids and surfaces. B, Biointerfaces, 2011, Oct-15, Volume: 87, Issue:2 Topics: Alginates; Calcium Chloride; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Emulsions; Glucuronic Acid; Hexoses; Hexuronic Acids; Humans; Hydrogels; Isoniazid; Lactic Acid; Microscopy, Electron, Scanning; Models, Molecular; Nanoparticles; Organic Chemistry Phenomena; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Spectrum Analysis; Thermodynamics; Tuberculosis	2011
An isoniazid analogue promotes Mycobacterium tuberculosis-nanoparticle interactions and enhances bacterial killing by macrophages. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5 Topics: Animals; Antitubercular Agents; Biological Availability; Cells, Cultured; Drug Compounding; Drug Delivery Systems; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Isoniazid; Lactic Acid; Macrophages; Mice; Microscopy, Atomic Force; Microscopy, Confocal; Mycobacterium tuberculosis; Nanoparticles; Particle Size; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tuberculosis, Pulmonary	2012
Permeation of PLGA nanoparticles across different in vitro models. Current drug delivery, 2012, Volume: 9, Issue:6 Topics: Biological Transport; Caco-2 Cells; Fluorescent Dyes; Humans; Intestinal Mucosa; Isoniazid; Lactic Acid; Membranes, Artificial; Nanoparticles; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Solubility	2012
In vivo/in vitro pharmacokinetic and pharmacodynamic study of spray-dried poly-(dl-lactic-co-glycolic) acid nanoparticles encapsulating rifampicin and isoniazid. International journal of pharmaceutics, 2013, Feb-28, Volume: 444, Issue:1-2 Topics: Animals; Antibiotics, Antitubercular; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Female; Isoniazid; Lactic Acid; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin	2013
Development and optimization of polymeric nanoparticles of antitubercular drugs using central composite factorial design. Expert opinion on drug delivery, 2014, Volume: 11, Issue:1 Topics: Animals; Antitubercular Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Isoniazid; Lactic Acid; Macrophages, Peritoneal; Male; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Rifampin	2014
Experimental study of PLLA/INH slow release implant fabricated by three dimensional printing technique and drug release characteristics in vitro. Biomedical engineering online, 2014, Jul-19, Volume: 13 Topics: Animals; Antitubercular Agents; Drug Carriers; Isoniazid; Lactic Acid; Materials Testing; Mesenchymal Stem Cells; Polyesters; Polymers; Printing, Three-Dimensional; Rats	2014
A mesoporous silicon/poly-(DL-lactic-co-glycolic) acid microsphere for long time anti-tuberculosis drug delivery. International journal of pharmaceutics, 2014, Dec-10, Volume: 476, Issue:1-2 Topics: Antitubercular Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Isoniazid; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin; Silicon Dioxide; Time Factors	2014
Nanoparticle encapsulated lipopeptide conjugate of antitubercular drug isoniazid: in vitro intracellular activity and in vivo efficacy in a Guinea pig model of tuberculosis. Bioconjugate chemistry, 2014, Dec-17, Volume: 25, Issue:12 Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Carriers; Female; Guinea Pigs; Humans; Isoniazid; Lactic Acid; Lipopeptides; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tuberculosis	2014
Determination of anti-tuberculosis drug concentration and distribution from sustained release microspheres in the vertebrae of a spinal tuberculosis rabbit model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017, Volume: 35, Issue:1 Topics: Animals; Antitubercular Agents; Disease Models, Animal; Drug Delivery Systems; Durapatite; Female; Isoniazid; Lactic Acid; Lumbar Vertebrae; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Tuberculosis, Spinal	2017
Development and Optimization of Dual Drugs (Isoniazid and Moxiflox-acin) Loaded Functional PLGA Nanoparticles for the Synergistic Treatment of Tuberculosis. Current drug delivery, 2016, Volume: 13, Issue:7 Topics: Anti-Bacterial Agents; Drug Carriers; Drug Liberation; Drug Resistance, Bacterial; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Isoniazid; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Moxifloxacin; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectroscopy, Fourier Transform Infrared; Tuberculosis	2016
Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics. Human & experimental toxicology, 2017, Volume: 36, Issue:6 Topics: Adenosine Triphosphate; Antitubercular Agents; Drug Interactions; Electron Transport Complex I; Electron Transport Complex III; Energy Metabolism; Hep G2 Cells; Humans; Isoniazid; Lactic Acid; Membrane Potential, Mitochondrial; NAD; Pyrazinamide; Rifampin	2017
Dopamine-assisted fixation of drug-loaded polymeric multilayers to osteoarticular implants for tuberculosis therapy. Biomaterials science, 2017, Mar-28, Volume: 5, Issue:4 Topics: Adhesives; Animals; Antitubercular Agents; Cell Line; Drug Delivery Systems; Drug Liberation; Female; Humans; Indoles; Isoniazid; Lactic Acid; Male; Mice; Mycobacterium tuberculosis; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prostheses and Implants; Rabbits; Tuberculosis, Osteoarticular	2017
Fabrication of Isoniazid/Rifampicin/Poly L-lactic Acid Donut-shaped Implants via Three Dimensional Printing Technique. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2017, Dec-20, Volume: 39, Issue:6 Topics: Delayed-Action Preparations; Isoniazid; Lactic Acid; Polyesters; Powders; Printing, Three-Dimensional; Prostheses and Implants; Rifampin	2017
Nanoparticle-based delivery of carbamazepine: A promising approach for the treatment of refractory epilepsy. International journal of pharmaceutics, 2018, Aug-25, Volume: 547, Issue:1-2 Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistant Epilepsy; Electrocorticography; Isoniazid; Lactic Acid; Male; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Verapamil	2018
Antimycobacterial susceptibility evaluation of rifampicin and isoniazid benz-hydrazone in biodegradable polymeric nanoparticles against International journal of nanomedicine, 2018, Volume: 13 Topics: A549 Cells; Animals; Antitubercular Agents; Biocompatible Materials; Cell Death; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Compounding; Drug Delivery Systems; Drug Liberation; Humans; Isoniazid; Lactic Acid; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proton Magnetic Resonance Spectroscopy; RAW 264.7 Cells; Rifampin; Static Electricity; Surface Tension; Tuberculosis	2018