lactic acid has been researched along with indazoles in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 6 (30.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Martino, C; Floridi, A; Malorni, W; Marcante, ML; Nista, A; Silvestrini, B | 1 |
| Caputo, A; Carapella, CM; Del Carlo, C; Fanciulli, M; Floridi, A; Giorno, S; Paggi, MG; Silvestrini, B; Zupi, G | 1 |
| De Martino, C; Malorni, W; Marolla, A; Natali, PG; Nista, A; Salsano, F; Viora, M | 1 |
| Battelli, T; D'Atri, S; De Martino, C; Floridi, A; Gallo, M; Malorni, W; Marcante, ML; Nista, A; Paggi, MG | 1 |
| Evans, WK; Mullis, B; Shepherd, FA | 1 |
| Cioli, V; Citro, G; D'Atri, S; De Martino, C; Feriozzi, R; Floridi, A; Marcante, ML; Menichini, R | 1 |
| Cipolloni, PB; Ferrante, RJ; Henshaw, DR; Jenkins, BG; Kowall, NW; Matthews, RT; Mecocci, P; Rosen, BR; Schulz, JB; Siwek, D | 1 |
| Ben-Yoseph, O; Lyons, JC; Ross, BD; Song, CW | 1 |
| Bruno, T; Di Padova, M; Fanciulli, M; Floridi, A; Gentile, FP; Giovannelli, A; Rubiu, O | 1 |
| Kaplan, O | 1 |
| Chang, YS; Lee, M; Park, WS | 2 |
| Allen, JC; Kahn, AM; Zhang, S | 1 |
| Al-Saffar, NM; Beloueche-Babari, M; Boult, JK; Chung, YL; Eykyn, TR; Hill, DK; Jafar, M; Jamin, Y; Leach, MO; Mariotti, E; Miniotis, MF; Orton, MR; Panek, R; Parkes, HG; Robinson, SP | 1 |
| Berger, W; Fischer, B; Gille, L; Heffeter, P; Keppler, BK; Kowol, CR; Kryeziu, K; Meier, SM | 1 |
| Arán, VJ; Marín, C; Muro, B; Navarro, P; Ramírez-Macías, I; Reviriego, F; Rosales, MJ; Sánchez-Moreno, M | 1 |
| Blair, IA; Glickson, JD; Guo, L; Halestrap, AP; Leeper, DB; Nancolas, B; Nath, K; Nelson, DS; Zhou, R | 1 |
| Allen, E; Hanahan, D; Li, L; Miéville, P; Peng, MW; Saghafinia, S; Warren, CM | 1 |
| Furugen, A; Futagi, Y; Iseki, K; Kobayashi, M; Narumi, K | 1 |
| Ren, C; Wang, Y; Xiu, J; Yang, T; Yu, Z | 1 |
20 other study(ies) available for lactic acid and indazoles
| Article | Year |
|---|---|
Effect of lonidamine on the aerobic glycolysis of normal and phytohemagglutinin-stimulated human peripheral blood lymphocytes.
Topics: Cell Survival; Glycolysis; Hexokinase; Humans; Indazoles; Lactates; Lactic Acid; Lymphocyte Activation; Lymphocytes; Mitochondrial Swelling; Ouabain; Phosphofructokinase-1; Phytohemagglutinins; Pyrazoles | 1985 |
Effect of lonidamine on human malignant gliomas: biochemical studies.
Topics: Astrocytoma; Deoxy Sugars; Deoxyglucose; Glycolysis; Hexokinase; Humans; Indazoles; Lactates; Lactic Acid; Pyrazoles; Tumor Cells, Cultured | 1988 |
Inhibition of aerobic glycolysis in normal and neoplastic lymphoid cells induced by Lonidamine [1-(2,4-dichlorobenzyl)-I-H-indazol-3-carboxylic acid].
Topics: Aerobiosis; B-Lymphocytes; Dose-Response Relationship, Drug; Glycolysis; Humans; In Vitro Techniques; Indazoles; Lactates; Lactic Acid; Leukemia; Microscopy, Electron; Phenotype; Pyrazoles; T-Lymphocytes | 1984 |
Effects of Lonidamine on murine and human tumor cells in vitro. A morphological and biochemical study.
Topics: Animals; Carcinoma, Ehrlich Tumor; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indazoles; Lactates; Lactic Acid; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Microscopy, Electron; Microscopy, Electron, Scanning; Mitochondria; Neoplasms; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Phase II evaluation of Lonidamine in patients with advanced malignancy.
Topics: Adult; Aged; Antineoplastic Agents; Auditory Perception; Digestive System; Drug Evaluation; Female; Humans; Indazoles; Lactates; Lactic Acid; Male; Middle Aged; Muscles; Neoplasms; Pyrazoles; Testosterone; Time Factors | 1984 |
Energy metabolism of normal and lonidamine-treated Sertoli cells of rats.
Topics: Aerobiosis; Animals; Antispermatogenic Agents; Cells, Cultured; Energy Metabolism; Glucose; Indazoles; Lactates; Lactic Acid; Male; Microscopy, Electron; Oxygen Consumption; Pyrazoles; Rats; Sertoli Cells | 1983 |
Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo.
Topics: Adenosine Triphosphate; Animals; Corpus Striatum; Electrophysiology; Gentisates; Hydroxybenzoates; Indazoles; Lactates; Lactic Acid; Male; Neurons; Neurotoxins; Nitric Oxide Synthase; Nitro Compounds; Propionates; Rats; Rats, Sprague-Dawley; Tyrosine | 1995 |
Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Gliosarcoma; Hydrogen-Ion Concentration; Indazoles; Injections, Subcutaneous; Intracellular Fluid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Muscle Neoplasms; Neoplasm Transplantation; Phosphorus Radioisotopes; Rats; Rats, Inbred F344; Thigh | 1998 |
Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence of lonidamine.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Carbon Dioxide; Cell Division; Citrate (si)-Synthase; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Energy Metabolism; Glucose; Hexokinase; Humans; Indazoles; Inhibitory Concentration 50; Isocitrate Dehydrogenase; Kinetics; Lactic Acid; Tumor Cells, Cultured | 2000 |
Correspondence re: M. Fanciulli et al., Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence fo lonidamine. Clin. Cancer Res., 6: 1590-1597, 2000.
Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Neoplasm; Glycolysis; Hexokinase; Humans; Indazoles; Lactic Acid; Tumor Cells, Cultured | 2000 |
7-Nitroindazole, but not aminoguanidine, attenuates the acute inflammatory responses and brain injury during the early phase of Escherichia coli meningitis in the newborn piglet.
Topics: Animals; Animals, Newborn; Blood Glucose; Brain Diseases; Cerebral Cortex; Cerebrospinal Fluid; Disease Models, Animal; Enzyme Inhibitors; Glucose; Guanidines; Indazoles; Inflammation; Lactic Acid; Leukocytosis; Lipid Peroxidation; Meningitis, Escherichia coli; Nitric Oxide Synthase; Swine; Tumor Necrosis Factor-alpha | 2001 |
Insulin increases NADH/NAD+ redox state, which stimulates guanylate cyclase in vascular smooth muscle.
Topics: Animals; Cells, Cultured; Cyclic GMP; Dogs; Guanylate Cyclase; Indazoles; Insulin; Isocitrates; Lactic Acid; Muscle, Smooth, Vascular; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxaloacetic Acid; Oxidation-Reduction; Pyruvic Acid; Stimulation, Chemical | 2002 |
Effect of 7-nitroindazole on bilirubin-induced changes in brain cell membrane function and energy metabolism in newborn piglets.
Topics: Animals; Animals, Newborn; Bilirubin; Blood Glucose; Cell Membrane; Cerebral Cortex; Drug Interactions; Energy Metabolism; Enzyme Inhibitors; Glucose; Indazoles; Kernicterus; Lactic Acid; Lipid Peroxidation; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Random Allocation; Sodium-Potassium-Exchanging ATPase; Statistics, Nonparametric; Swine | 2002 |
Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data.
Topics: Animals; Cell Line, Tumor; Humans; Indazoles; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Mice; Models, Theoretical; Pyruvates; Sulfonamides; Xenograft Model Antitumor Assays | 2013 |
Poly(lactic acid) nanoparticles of the lead anticancer ruthenium compound KP1019 and its surfactant-mediated activation.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Indazoles; Kinetics; Lactic Acid; Nanoparticles; Organometallic Compounds; Particle Size; Polyesters; Polymers; Polysorbates; Reactive Oxygen Species; Ruthenium Compounds | 2014 |
In vitro leishmanicidal activity of 1,3-disubstituted 5-nitroindazoles.
Topics: Acetates; Alanine; Animals; Antiprotozoal Agents; Glycine; In Vitro Techniques; Indazoles; Lactic Acid; Leishmania braziliensis; Leishmania infantum; Leishmaniasis, Visceral; Macrophages; Magnetic Resonance Spectroscopy; Mice; Microscopy, Electron, Transmission; Mitochondria; Organelles; Pyruvic Acid; Succinic Acid | 2015 |
The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Membrane; Indazoles; Ion Transport; Lactic Acid; Male; Membrane Transport Proteins; Mitochondrial Proteins; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Wistar; Solute Carrier Proteins; Symporters | 2016 |
Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling.
Topics: Angiogenesis Inhibitors; Animals; Axitinib; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycolysis; Humans; Imidazoles; Indazoles; Indoles; Intestinal Neoplasms; Lactic Acid; Membrane Transport Proteins; Mice; Models, Biological; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Signal Transduction; Sirolimus; Stomach Neoplasms; Sunitinib; TOR Serine-Threonine Kinases; Up-Regulation | 2016 |
Identification of a selective inhibitor of human monocarboxylate transporter 4.
Topics: Animals; Biological Transport; Cells, Cultured; Drug Discovery; Female; Fibric Acids; Humans; Indazoles; Isobutyrates; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Oocytes; Propionates; Protein Isoforms; Xenopus laevis | 2018 |
HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression.
Topics: Aminopyridines; Animals; Blotting, Western; Cell Count; Cell Line; Cell Movement; Cell Proliferation; Disease Models, Animal; Endometriosis; Female; Gene Knockdown Techniques; Glucose; Glycolysis; Heat Shock Transcription Factors; Humans; Indazoles; Lactic Acid; Mice; Phosphofructokinase-2; Real-Time Polymerase Chain Reaction; Up-Regulation | 2021 |