lactic acid and gossypol

lactic acid has been researched along with gossypol in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's5 (35.71)18.2507
2000's3 (21.43)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Den Boer, PJ; Grootegoed, JA1
Jänne, J; Käpyaho, K; Sinervirta, R; Wichmann, K1
Den, Y; Huang, Y; Lu, G; Xue, S; Ye, W1
Javed, MH; Waqar, MA1
Clarke, AR; Dewar, V; Holbrook, JJ; Sessions, RB1
Deck, LM; Gomez, MS; Hunsaker, LA; Makler, MT; Piper, RC; Royer, RE; Vander Jagt, DL1
Miska, W; Monsees, TK; Schill, WB; Winterstein, U1
Deck, JA; Deck, LM; Goldberg, E; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Yu, Y1
Ames, ML; Rasmussen, MA; Reilly, PJ; Schneider, IC1
Dhar, JD; Dwivedi, AK; Gupta, G; Ojha, P; Singh, RL1
Aizen, R; Aleman-Garcia, MA; Heleg-Shabtai, V; Orbach, R; Willner, I1
Judge, JL; Kottmann, RM; Owens, KM; Phipps, RP; Pollock, SJ; Sime, PJ; Thatcher, TH; Williams, JP; Woeller, CF1
Epa, AP; Judge, JL; Kottmann, RM; Owens, KM; Phipps, RP; Sime, PJ; Thatcher, TH; Trawick, E; Wahl, LA1

Other Studies

14 other study(ies) available for lactic acid and gossypol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mechanism of action of (-)gossypol on ATP production in isolated hamster spermatids.
    Journal of reproduction and fertility, 1988, Volume: 83, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Cricetinae; Gossypol; Isoenzymes; Isomerism; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Male; Mesocricetus; Spermatids

1988
Effect of gossypol on the motility and metabolism of human spermatozoa.
    Journal of reproduction and fertility, 1983, Volume: 69, Issue:1

    Topics: Adenosine Triphosphate; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Fructose; Glucose; Gossypol; Humans; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sperm Motility; Spermatozoa; Vagina

1983
Effect of intra-vas deferens injection of gossypol-polylactic acid on fertility and spermatogenesis in rats.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1993, Volume: 8, Issue:1

    Topics: Animals; Delayed-Action Preparations; Drug Delivery Systems; Fertility; Gossypol; Lactates; Lactic Acid; Male; Polyesters; Polymers; Rats; Rats, Wistar; Spermatogenesis; Spermatozoa; Testis; Vas Deferens

1993
Protective effect of histidine by inhibition of gossypol on rat's liver LDH-5.
    Biochemical Society transactions, 1995, Volume: 23, Issue:4

    Topics: Animals; Fertility; Gossypol; Histidine; In Vitro Techniques; Isoenzymes; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats

1995
A model of Plasmodium falciparum lactate dehydrogenase and its implications for the design of improved antimalarials and the enhanced detection of parasitaemia.
    Protein engineering, 1997, Volume: 10, Issue:4

    Topics: Amino Acid Sequence; Animals; Antimalarials; Binding Sites; Crystallography, X-Ray; Drug Design; Geobacillus stearothermophilus; Gossypol; Humans; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Models, Chemical; Models, Molecular; Molecular Sequence Data; NAD; Plasmodium falciparum; Protein Structure, Tertiary; Sequence Alignment; Sequence Deletion; Stereoisomerism; Swine

1997
Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum.
    Molecular and biochemical parasitology, 1997, Dec-01, Volume: 90, Issue:1

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Enzyme Inhibitors; Gossypol; Humans; Isoelectric Point; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Molecular Sequence Data; NAD; Plasmodium falciparum; Pyruvic Acid; Recombinant Proteins; Substrate Specificity

1997
Influence of gossypol on the secretory function of cultured rat sertoli cells.
    Toxicon : official journal of the International Society on Toxinology, 1998, Volume: 36, Issue:5

    Topics: Animals; Cell Death; Cell Survival; Cells, Cultured; Cottonseed Oil; Dose-Response Relationship, Drug; Gossypol; Inhibins; Lactic Acid; Male; Mitochondria; Oxidoreductases; Rats; Rats, Sprague-Dawley; Sertoli Cells; Spermatogenesis

1998
Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4.
    Biochemical pharmacology, 2001, Jul-01, Volume: 62, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Energy Metabolism; Enzyme Inhibitors; Gossypol; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Molecular Sequence Data; Oxamic Acid; Sequence Homology, Amino Acid; Structure-Activity Relationship

2001
Fermentation of cottonseed and other feedstuffs in cattle rumen fluid.
    Journal of agricultural and food chemistry, 2002, Apr-10, Volume: 50, Issue:8

    Topics: Acetates; Animal Feed; Animals; Body Fluids; Butyrates; Cattle; Cottonseed Oil; Fermentation; Gossypol; Lactic Acid; Medicago sativa; Pentanoic Acids; Propionates; Rumen; Zea mays

2002
Effect of antispermatogenic agents on cell marker enzymes of rat Sertoli cells in vitro.
    Contraception, 2006, Volume: 73, Issue:1

    Topics: Animals; Antispermatogenic Agents; Aromatase; Cells, Cultured; gamma-Glutamyltransferase; Glucuronidase; Gossypol; L-Lactate Dehydrogenase; Lactic Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Sertoli Cells

2006
Gossypol-cross-linked boronic acid-modified hydrogels: a functional matrix for the controlled release of an anticancer drug.
    Langmuir : the ACS journal of surfaces and colloids, 2015, Feb-24, Volume: 31, Issue:7

    Topics: Antineoplastic Agents; Boronic Acids; Delayed-Action Preparations; Formates; Gossypol; Hydrogels; Hydrogen-Ion Concentration; Lactic Acid

2015
Ionizing radiation induces myofibroblast differentiation via lactate dehydrogenase.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Oct-15, Volume: 309, Issue:8

    Topics: Animals; Cell Differentiation; Cells, Cultured; Enzyme Inhibitors; Gossypol; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Lung; Mice; Mice, Inbred C57BL; Models, Biological; Myofibroblasts; Pulmonary Fibrosis; Radiation Injuries; Transforming Growth Factor beta

2015
Pharmacologic inhibition of lactate production prevents myofibroblast differentiation.
    American journal of physiology. Lung cellular and molecular physiology, 2015, Dec-01, Volume: 309, Issue:11

    Topics: Animals; Cell Differentiation; Cell Line; Enzyme Inhibitors; Extracellular Matrix; Gene Knockdown Techniques; Gossypol; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lung; Mink; Myofibroblasts; Pulmonary Fibrosis; Tissue Donors; Transforming Growth Factor beta

2015