lactic acid has been researched along with glutamine in 436 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (12.61) | 18.7374 |
| 1990's | 106 (24.31) | 18.2507 |
| 2000's | 114 (26.15) | 29.6817 |
| 2010's | 130 (29.82) | 24.3611 |
| 2020's | 31 (7.11) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, CB; Goguen, JM; Halperin, ML | 1 |
| Brewis, IA; Leese, HJ; Winston, RM | 1 |
| Dejong, CH; Deutz, NE; Kampman, MT; Soeters, PB | 1 |
| Greene, LW; Wu, G | 1 |
| Fiechter, A; Kurano, N; Kurano, S; Leist, C; Messi, F | 1 |
| Griffiths, JB; Looby, D; Racher, AJ | 1 |
| Kunas, KT; Papoutsakis, ET | 1 |
| Kargi, F; Shaughnessy, TS | 2 |
| Baines, AJ; Bull, AT; Curling, EM; Hayter, PM; Jenkins, N; Salmon, I; Strange, PG | 1 |
| Jäger, V; Kaiser, G; Lietz, M; Pawlowa, M; Renneberg, R; Schmid, RD; Schubert, F; Trott-Kriegeskorte, G; Wagner, R; Wollenberger, U | 1 |
| Schlaeger, EJ; Schumpp, B | 2 |
| Bols, NC; Moo-Young, M; Phillips, HA; Scharer, JM | 1 |
| Engasser, JM; Goergen, JL; Marc, A | 1 |
| Chengson, R; Dallman, PR; Jones, PH; Willis, WT | 1 |
| Chedeville, A; Claeyssens, S; Lavoinne, A; Mouterde, O | 1 |
| Bosman, DK; Bovee, WM; Chamuleau, RA; de Graaf, AA; de Haan, JG; Deutz, NE | 1 |
| Fine, A | 1 |
| Ernst, T; Hennig, J | 1 |
| Badía, A; López-Farré, A; López-Novoa, JM; Montañés, I; Rengel, MA | 1 |
| Chu, CL; Leonard, M; Olmedo, R; Scher, BM; Scher, GS; Scher, W; Stecker, S; Waxman, S; Wu, H | 1 |
| Field, CJ; Marliss, EB; Wu, GY | 2 |
| Asskali, F; Encke, A; Förster, H; Sachs, M | 1 |
| Dunham, CM; Fabian, M; Gettings, L; Siegel, JH | 2 |
| Coraim, FI; Haumer, H; Simon, P; Trubel, W | 1 |
| Bagby, GJ; Lang, CH; Spitzer, JJ; Spolarics, Z | 1 |
| Bavister, BD; McKiernan, SH; Tasca, RJ | 1 |
| Almond, MK; Cohen, RD; Flynn, G; Iles, RA; Smith, A | 1 |
| Butler, M; Hassell, T | 1 |
| Ardawi, MS; Kateilah, SM; Majzoub, MF; Newsholme, EA | 1 |
| Davies, KP; Köhler, P | 1 |
| Blondeau, K; Demangel, C; Duval, D; Geahel, I; Marcadet, A | 1 |
| Kenney, R; Parrish, A; Tomacelli, C; Zikira, M | 1 |
| Behar, KL; Fitzpatrick, SM; Hetherington, HP; Shulman, RG | 1 |
| Bates, TE; Gadian, DG; Kauppinen, RA; Williams, SR | 1 |
| Matsuno, T | 2 |
| Placko, R; Siegel, JH; Vary, TC | 1 |
| Baverel, G; Martin, G; Michoudet, C | 1 |
| Baille, TA; Bennett, JL; Bjorge, SM; Geary, TG; Gooley, PR; MacKenzie, NE; Van de Waa, EA; Williams, JF | 1 |
| Murphy, JM; Vary, TC | 1 |
| Bruhn, H; Frahm, J; Gyngell, ML; Hamburger, C; Hänicke, W; Merboldt, KD; Sauter, R | 1 |
| Alonso, FJ; Medina, MA; Núñez de Castro, I; Sanchez-Jimenez, F; Segura, JA | 1 |
| Fischer, B; Holm, E; Jacob, S | 1 |
| Blachier, F; Malaisse, WJ; Sener, A | 1 |
| Endou, H; Uchida, S | 1 |
| Behar, KL; den Hollander, JA; Hetherington, HP; Petroff, OA; Prichard, JW; Shulman, RG | 1 |
| Lin, S; Raabe, W | 1 |
| Aranda, MR; Ibanez, RJ; Kiss, AL; Lemieux, C; Lemieux, G | 1 |
| Charlier, AA; Cheron, P; Pouleur, H; Rousseau, MF; van den Berghe, G; Vincent, MF | 1 |
| Allignet, E; Junco, E; Lemieux, C; Lemieux, G; Perez, R | 1 |
| Henriksson, J; Katz, A; Sahlin, K | 1 |
| Curi, R; Kowalchuk, JM; Newsholme, EA | 1 |
| Grunewald, RW; Jans, AW; Kinne, RK | 1 |
| Grieshaber, MK; Kreutzer, U; Rösen, P; Wiesner, RJ | 1 |
| Fagan, JM; Tischler, ME | 1 |
| Boulanger, Y; Cantin, M; Gougoux, A; Lalonde, L; Manillier, C; Thibault, G; Vinay, P | 1 |
| Carpinelli, AR; Dufrane, SP; Garcia-Morales, P; Malaisse, WJ; Malaisse-Lagae, F; Mathias, PC; Sener, A; Valverde, I | 1 |
| Chin, NW; Hitti, IF; Lanks, KW | 1 |
| Bourke, E; Preuss, HG; Roxe, DM | 1 |
| Baquet, A; Hue, L; Lavoinne, A | 1 |
| Lanks, KW | 2 |
| Gougoux, A; Halperin, M; Lemieux, G; Vinay, P | 1 |
| Manning, CD; Matschinsky, FM; Meglasson, MD; Najafi, H | 1 |
| Macmillan, JD; Miller, L; Reuveny, S; Velez, D | 1 |
| Gordon, S; Newsholme, EA; Newsholme, P | 1 |
| Gougoux, A; Noel, J; Tejedor, A; Vinay, P; Zizian, L | 1 |
| Brkljac, O; Kovacević, Z; Lelas, S; Popović, J | 1 |
| Areas, J; Lenhart, M; Preuss, HG; Schubert, P; Slemmer, D | 1 |
| Gougoux, A; Lalonde, L; Manillier, C; Vinay, P | 1 |
| Mandel, LJ | 1 |
| Cheema-Dhadli, S; Chen, CB; Halperin, ML | 1 |
| Marchok, AC; Wasilenko, WJ | 1 |
| Blondin, J; Delmez, JA; Klahr, S; Rutherford, WE | 1 |
| Belanger, P; Lemieux, G; Preuss, HG; Sleeper, RS | 1 |
| Baverel, G; Martin, G | 1 |
| Caldecourt, MA; Palmer, TN; Sugden, MC; Warner, JP | 1 |
| Amos, H; Miller, MH; Sens, DA | 1 |
| Eigenbrodt, E; Fister, P; Schoner, W | 1 |
| Amos, H; Hochstadt, B; Sens, DA | 1 |
| Craan, AG; Gougoux, A; Lemieux, G; Vinay, P | 1 |
| Hems, R; Saez, GT | 1 |
| Babij, P; Matthews, SM; Rennie, MJ | 1 |
| Chen, KS; Lardy, HA | 1 |
| Penn, CW; Smith, H; Veale, DR | 1 |
| Rognstad, R | 1 |
| Dauchy, RT; Sauer, LA | 1 |
| Betteridge, KJ; Dessy, F; Grisart, B; Rieger, D; Semple, E; Van Langendonckt, A | 1 |
| Bier, DM; Dailey, G; Gerich, JE; Jenssen, T; Jorde, R; Nurjhan, N; Perriello, G; Stumvoll, M | 1 |
| Chang, C; Jang, T | 1 |
| Bryła, J; Lietz, T | 1 |
| Amaducci, L; Latorraca, S; Piacentini, S; Piersanti, P; Sorbi, S | 1 |
| Hashizume, S; Kato, M; Mochizuki, K; Sato, S | 1 |
| Greenfield, P; Reid, S; Shen, B | 1 |
| Biselli, M; Eberhardt, R; Gaetgens, J; Spohn, U; Tramper, J; van der Pol, JJ; Wandrey, C | 1 |
| Butler, M; Christie, A | 1 |
| Behar, KL; Gruetter, R; Mason, GF; Novotny, EJ; Rothman, DL; Shulman, RG | 1 |
| Bernard, F; Darcy-Vrillon, B; Duée, PH; Morel, MT; Posho, L; Vaugelade, P | 1 |
| Castell, LM; Desborough, JP; Hall, GM; Newsholme, EA; Parry-Billings, M; Powell, H | 1 |
| Blannin, AK; Gleeson, M; Sewell, DA | 1 |
| Barclay, JK; Graham, TE; MacLean, DA | 1 |
| Katz, J; Lee, WN; Wals, P | 1 |
| Erecińska, M; Nelson, D | 1 |
| Baverel, G; Chauvin, MF; Lhoste, JM; Martin, G; Mégnin-Chanet, F | 1 |
| Bernard, F; Blachier, F; Darcy-Vrillon, B; Duée, PH; Meslin, JC; Morel, MT; Posho, L | 1 |
| Behar, KL; Petroff, OA; Rothman, DL; Spencer, DD | 1 |
| Blankenstein, G; Kula, MR; Preuschoff, F; Spohn, U; Thömmes, J | 1 |
| Dejong, CH; Deutz, NE; Soeters, PB | 1 |
| Bachelard, HS; Badar-Goffer, RS; Ben-Yoseph, O; Morris, PG | 1 |
| Petersen, SB; Schousboe, A; Sonnewald, U; Unsgård, G; Westergaard, N | 1 |
| Jackson, MJ; Max, SR; Tildon, JT; Zielke, HR | 1 |
| Medina, JM; Tabernero, A; Vicario, C | 1 |
| Booth, IW | 1 |
| Hattori, M; Hiraoka, A; Kushida, K; Maeda, M; Miura, I; Tominaga, I | 1 |
| Baverel, G; Chauvin, MF; Michoudet, C | 1 |
| Bond, JA; Calder, PC; Curi, R; Newsholme, EA | 1 |
| Bernard, F; Blachier, F; Cherbuy, C; Darcy-Vrillon, B; Duee, PH; Meslin, JC; Morel, MT; Posho, L | 1 |
| Crabb, DW; Sidhu, R | 1 |
| Neermann, J; Wagner, R | 1 |
| Biselli, M; de Gooijer, CD; Gätgens, J; Joksch, B; Tramper, J; van der Pol, JJ; Wandrey, C | 1 |
| Baverel, G; Combet, J; Dugelay, S; Fouque, D; Martin, G | 1 |
| Dijkhuizen, RM; Nicolay, K; Tulleken, CA; van der Toorn, A | 1 |
| Cabacungan, ET; Fox, RE; Hopkins, IB; Tildon, JT | 1 |
| Canioni, P; Merle, M; Portais, JC; Voisin, P | 1 |
| Pörtner, R; Schäfer, T | 1 |
| Curi, R; Fernandes, LC; Machado, UF; Mattozo, CA; Rosa, LF | 1 |
| Costa Rosa, LF; Guimarães, AR; Safi, DA | 1 |
| Agarwal, KC; Beylot, M; Brunengraber, H; David, F; Dugelay, S; Fernandez, CA; Hazey, JW; Levine, WC; Previs, SF; Rinaldo, P; Soloviev, MV; Yang, D | 1 |
| Gardner, DK; Lane, M | 1 |
| Angelini, GD; Bryan, AJ; Caputo, M; Dihmis, WC; Hutter, JA; Moffatt, AC; Suleiman, MS | 1 |
| Bavister, BD; Kito, S | 1 |
| Guth, HJ; Kraatz, G; Rose, HJ; Wiersbitzky, M; Ziesche, M | 1 |
| Felber, S; Skladal, D; Sperl, W; Wermuth, B | 1 |
| Bryła, J; Lietz, T; Winiarska, K | 1 |
| Bachelard, H; Fonnum, F; Hassel, B; Jones, P; Sonnewald, U | 1 |
| Cerra, FB; Gruetter, R; Nyberg, SL | 1 |
| Bishop, NC; Blannin, AK; Clark, AM; Gleeson, M; Walsh, NP | 1 |
| Claville, W; Langford, M; Welbourne, T | 1 |
| Blannin, AK; Clark, AM; Cook, L; Gleeson, M; Robson, PJ; Walsh, NP | 1 |
| Braun, WA; Davis, BJ; Forrest, MB; Mitchell, JB; Paquet, A; Pizza, FX | 1 |
| Chapkin, RS; Lupton, JR; Wu, G; Zhang, J | 1 |
| Blain, H; Guéant, JL; Jeandel, C; Lefebvre, E; Redjems-Bennani, N; Vidailhet, M | 1 |
| Gruetter, R; Kim, S; Seaquist, ER; Ugurbil, K | 1 |
| Heerschap, A; van den Bergh, AJ; van den Boogert, HJ | 1 |
| Bozko, P; Bryła, J; Lietz, T; Winiarska, K | 1 |
| Bavister, BD; Libersky-Williamson, EA; Rose-Hellekant, TA | 1 |
| Blannin, AK; Castell, LM; Gleeson, M; Robson, PJ; Walsh, NP | 1 |
| Dillon, EL; Knabe, DA; Wu, G | 1 |
| Griffin, JL; Matthews, PM; Radda, GK; Rae, C | 1 |
| Biramane, J; Devreker, F; Englert, Y; Hardy, K; Van den Bergh, M; Winston, RL | 1 |
| Beylot, M; Diraison, F; Krempf, M; Large, V; Maugeais, C | 1 |
| Carrondo, MJ; Cruz, HJ; Moreira, JL | 1 |
| Bazotte, RB; Borba-Murad, GR; Ceddia, RB; Curi, R; Lopes, G; Souza, HM; William, WN | 1 |
| Amado, CB; Bracht, A; Fedatto Júnior, Z; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Panerari, AD; Vicentini, GE | 1 |
| Arthur, P; Guppy, M; Hill, DJ; Rowley, AF | 1 |
| MacLeish, PR; Poitry, S; Poitry-Yamate, C; Tsacopoulos, M; Ueberfeld, J | 1 |
| Battaglia, FC; Fennessey, P; Meschia, G; Teng, C; Timmerman, M; Wilkening, RB | 1 |
| Ruokonen, ET; Suojaranta-Ylinen, RT; Takala, JA | 1 |
| Harano, M; Kawada, N; Ryozo, N; Takakura, N; Tanaka, N; Tsuge, H | 1 |
| Barker, GJ; Duncan, JS; McLean, MA; Woermann, FG | 1 |
| Apkarian, AV; Grachev, ID | 2 |
| Brand, A; Leibfritz, D; Richter-Landsberg, C; Zwingmann, C | 1 |
| Apkarian, VA; Fredrickson, BE; Grachev, ID | 1 |
| Kamen, A; Koehl, M; Nadeau, I; Perrier, M; Sabatié, J | 1 |
| O'Regan, MH; Phillis, JW; Ren, J | 1 |
| Battaglia, FC; Chung, M; Teng, C; Timmerman, M; Wilkening, RB | 1 |
| Apkarian, AV; Grachev, ID; Ramachandran, TS; Swarnkar, A; Szeverenyi, NM | 1 |
| Leibfritz, D; Richter-Landsberg, C; Zwingmann, C | 1 |
| Akimoto, LS; Bazotte, RB; Lopes, G; Pedrinho, SR | 1 |
| Le Maire, T; Qu, H; Sonnewald, U; van der Gaag, M | 1 |
| Bazotte, RB; Borba-Murad, GR; Ceddia, RB; Curi, R; de Souza, HM; Vardanega-Peicher, M | 1 |
| Blomstrand, E; Saltin, B | 1 |
| Décorps, M; Rémy, C; von Kienlin , M; Ziegler, A | 1 |
| Larsson, OM; Schousboe, A; Sonnewald, U; Waagepetersen, HS | 1 |
| Cogoli, A; Gmunder, FK; Lorenzi, G | 1 |
| Bouzier-Sore, AK; Canioni, P; Merle, M | 1 |
| Chan, ST; Ho, PC; Lee, YL; Xu, JS; Yeung, WS | 1 |
| Baverel, G; Conjard, A; Ferrier, B; Guitton, J; Martin, M | 1 |
| Fonnum, F; Hassel, B; Johannessen, CU; Qu, H; Sonnewald, U | 1 |
| Butler, M; Huzel, N; Wang, MD; Yang, M | 1 |
| Dostou, J; Gerich, J; Haymond, M; Meyer, C; Stumvoll, M; Welle, S | 1 |
| Battaglia, FC; Meschia, G; Narkewicz, MR; Teng, C; Wilkening, RB | 1 |
| Hu, S; Li, JY; Lu, Y; Sun, D; Yao, YM | 1 |
| Jobst, G; Moser, I; Urban, GA | 1 |
| Friedl, P; Schäfer, R; Schröder, M | 1 |
| Sun, XM; Zhang, YX | 1 |
| Balcar, VJ; Bubb, WA; Mitrovic, AD; Moussa, Cel-H; Provis, T; Rae, C; Vandenberg, RJ | 1 |
| Chan, BS; Endo, S; Kanai, N; Schuster, VL | 1 |
| Ammatuna, M; Battezzati, A; Caumo, A; Coppa, J; Fattorini, A; Luzi, L; Mazzaferro, V; Regalia, E; Romito, R; Sereni, LP | 1 |
| Bachmann, C; Boulat, O; Braissant, O; Henry, H; Honegger, P; Pardo, B; Zurich, MG | 1 |
| Chadha, PL; Crandall, SC; Qureshi, T; Sumida, KD | 1 |
| Auniņs, JG; Leung, J; Metallo, C; Pikus, L; Pilbrough, W; Xie, L; Zhong, T; Zhou, W | 1 |
| Bacurau, RF; Bassit, RA; Costa Rosa, LF; Martins, E; Navarro, F; Sawada, L | 1 |
| Brinker, T; Kondziella, D; Lüdemann, W; Qu, H; Sletvold, O; Sonnewald, U | 1 |
| dos Santa Costa, A; Lancha, AH; Marquezi, ML; Roschel, HA; Sawada, LA | 1 |
| Balcar, VJ; Bröer, A; Bröer, S; Bubb, WA; Conigrave, AD; Hare, N; McEwan, SR; McQuillan, JA; Rae, C | 1 |
| Bui, BV; Kalloniatis, M; Vingrys, AJ | 1 |
| Andrieux, C; Babakissa, C; Bernard, F; Cherbuy, C; Colomb, V; Corriol, O; Darcy-Vrillon, B; Duée, PH; Popot, F; Ricour, C; Vaugelade, P | 1 |
| Blum, LJ; Degiuli, A; Marquette, CA; Thomas, D | 1 |
| Arnold, SA; Crowley, J; Harvey, LM; McNeil, B; Woods, N | 1 |
| Brazão, TF; Carrondo, MJ; Maranga, L | 1 |
| McClure, BG; Thompson, SW; Tubman, TR | 1 |
| Cemal, CK; Griffin, JL; Pook, MA | 1 |
| Forsberg, AM; Garlick, PJ; Rooyackers, O; Tjäder, I; Vesali, RF; Wernerman, J | 1 |
| King, N; Lin, H; McGivan, JD; Suleiman, MS | 1 |
| Etcheverrigaray, M; Fogolín, MB; Kratje, R; Wagner, R | 1 |
| Altamirano, C; Cairó, JJ; Gòdia, F; Illanes, A; Paredes, C | 1 |
| Behrendt, I; Genzel, Y; König, S; Reichl, U; Sann, H | 1 |
| Arnold, MA; Cohen, MB; Murhammer, DW; Rhiel, MH | 1 |
| Wang, H; Wu, GH; Wu, ZG; Wu, ZH; Zhang, YW | 1 |
| Bernal, F; Fredriksson, K; Mahy, N; Ramonet, D; Rodríguez, MJ | 1 |
| Downie, MM; Kealey, T | 1 |
| Dager, SR; Demopulos, C; Dunner, DL; Friedman, SD; Hirashima, F; Lyoo, IK; Parow, A; Renshaw, PF; Stoll, AL | 1 |
| McKnight, TR | 1 |
| Baverel, G; Gauthier, C; Martin, G; Michoudet, C; Vittorelli, A | 1 |
| Beuger, S; Boer, K; Godfried, MH; Kuijpers, TW; Scherpbier, HJ | 1 |
| Abi-Saab, WM; Cassaday, MP; Cavus, I; Gueorguieva, R; Jacob, R; Kasoff, WS; Krystal, JH; Sherwin, RS; Spencer, DD | 1 |
| Juchem, C; Logothetis, NK; Merkle, H; Nauerth, A; Pfeuffer, J | 1 |
| Hertz, L; Kala, G | 1 |
| Alexander, JJ; Quigg, R; Zwingmann, C | 1 |
| Dalm, MC; Jansen, M; Keijzer, TM; Martens, DE; Oudshoorn, A; Tramper, J; van Grunsven, WM | 1 |
| Chang, KM; Chu, A; Ho, L; Hsieh, SY; Ou, JJ; Shaw, SY; Wang, IK; Wang, YC | 1 |
| Bartnik, BL; Fukushima, M; Harris, NG; Hovda, DA; Lee, SM; Sutton, RL | 1 |
| Calvani, M; Conti, F; Manetti, C; Miccheli, A; Peluso, G; Puccetti, C; Tomassini, A; Tuccillo, F; Valerio, M | 1 |
| Hammarqvist, F; Johansson, G; Luo, JL; Söderlund, K; Wernerman, J; Westman, B | 1 |
| Jayakumar, AR; Norenberg, MD; Rao, KV | 1 |
| Bilodeau-Goeseels, S | 1 |
| Baverel, G; Bodin, S; Boghossian, M; Conjard, A; Delage, H; Eid, A; Ferrier, B; Martin, M | 1 |
| Fischer, M; Genzel, Y; Reichl, U | 1 |
| Goochee, CF; Maranga, L | 1 |
| Alves, PM; Carrondo, MJ; Coroadinha, AS; Cruz, PE; Merten, OW; Santos, SS | 1 |
| Agascioglu, E; Giroix, MH; Malaisse, WJ; Sener, A | 1 |
| Bernier, JF; Doepel, L; Dubreuil, P; Gagnon, N; Lapierre, H; Lessard, M; Lobley, GE | 1 |
| Fernández, M; Zúñiga, M | 1 |
| Blanch, HW; Clark, DS; Forbes, NS; Meadows, AL | 1 |
| Biener, R; Goudar, C; Konstantinov, K; Michaels, J; Piret, J; Zhang, C | 1 |
| Tian, H; Wang, KF; Wu, TJ | 1 |
| Bowtell, JL; Marwood, S | 1 |
| Enblad, P; Hesselager, G; Hillered, L; Kumlien, E; Lewén, A; Marklund, N; Nilsson, P; Ronne-Engström, E; Ryttlefors, M; Salci, K; Samuelsson, C; Zetterling, M | 1 |
| Chen, L; Chen, Y; Gu, S; Hong, M; Sun, X; Zhang, L | 1 |
| Lacza, Z; Murányi, M | 1 |
| Andrews, MT; Drewes, LR; Gruetter, R; Henry, PG; Russeth, KP; Tkac, I | 1 |
| Bartnik, BL; Hovda, DA; Lee, SM; Sutton, RL | 1 |
| Belanger, M; Davies, NA; Jalan, R; Nedredal, GI; Revhaug, A; Rose, C; Sen, S; Ytrebø, LM | 1 |
| Flatt, PR; Kiely, A; McClenaghan, NH; Newsholme, P | 1 |
| Dimitriadis, G; Newsholme, EA | 1 |
| Huang, Q; Li, J; Li, N; Li, Q; Wang, B; Zhang, W; Zhu, W | 1 |
| Bjerring, PN; Frederiksen, HJ; Hansen, BA; Hauerberg, J; Jorgensen, L; Larsen, FS; Tofteng, F | 1 |
| Chen, HB; Gao, J; Li, L; Li, XQ; Yan, XZ; Zhang, Q | 1 |
| Bowtell, J; Marwood, S | 1 |
| de Graaf, RA; Dijkhuizen, RM; van der Zijden, JP; van Eijsden, P | 1 |
| Chen, L; Gu, S; Hong, M; Li, E; Qin, JG; Sun, X; Yu, N | 1 |
| Bazotte, RB; Curi, R; Felisberto-Junior, AM; Garcia, RF; Oliveira-Yamashita, F | 1 |
| Bloem, RM; de Bruijn, JD; Fernandes, H; Janssen, FW; Schop, D; van Dijkhuizen-Radersma, R; van Rijn, LD | 1 |
| Higuera, G; Janssen, F; Schop, D; van Blitterswijk, CA; van Boxtel, T; van Dijkhuizen-Radersma, R | 1 |
| Egenberger, B; Gorboulev, V; Gorbunov, D; Koepsell, H; Müller, T; Schlachtbauer, P; Schmitt, BM; Wischmeyer, E | 1 |
| Berthet, C; Gruetter, R; Hirt, L; Lei, H | 1 |
| Baldwin, RL; Bequette, BJ; El-Kadi, SW; McLeod, KR; Sunny, NE | 1 |
| Aragão, Mde F; Law, M; Naidich, T; Netto, JP; Valença, MM | 1 |
| Deelchand, DK; Eberly, LE; Henry, PG; Iltis, I; Koski, DM; Lim, KO; Nelson, CD; Ugurbil, K; Valette, J | 1 |
| Babaeipour, V; Farnoud, AM; Khalilzadeh, R; Ranjbar, B; Sadeghyzadeh, M; Shojaosadati, SA; Yegane-Sarkandy, S | 1 |
| Bresolin, N; Brighina, E; Pardi, G; Rango, M | 1 |
| Cruz, NF; Dienel, GA | 1 |
| Fiskum, G; Hopkins, I; McKenna, M; O'Brien, J; Robertson, C; Scafidi, S | 1 |
| Enblad, P; Hillered, L; Howells, T; Kumlien, E; Ronne-Engström, E; Samuelsson, C | 1 |
| Babu, CS; Ramanathan, M | 1 |
| Bertheussen, K; Elvevold, K; Fuskevåg, OM; McCourt, PA; Nedredal, GI; Pettersen, I; Revhaug, A; Smedsrød, B; Ytrebø, LM | 1 |
| Buschmann, MD; Gigout, A; Girard-Lauriault, PL; Jolicoeur, M; Levasseur, S; Wertheimer, MR | 1 |
| Carpenter, KL; Gallagher, CN; Grice, P; Howe, DJ; Hutchinson, PJ; Kirkpatrick, PJ; Mason, A; Menon, DK; Pickard, JD; Sutherland, GR; Timofeev, I | 1 |
| Acosta, ML; Bui, BV; Donaldson, P; Hu, RG; Kalloniatis, M; Vingrys, AJ | 1 |
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| Dutta, T; Ghosh, T; Gonsalves, WI; Hitosugi, T; Jevremovic, D; Kumar, SK; Nair, KS; Petterson, XM; Ramakrishnan, V; Sakrikar, D; Wellik, L | 1 |
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26 review(s) available for lactic acid and glutamine
| Article | Year |
|---|---|
Regulation of glutamine metabolism in dog kidney in vivo.
Topics: Acid-Base Equilibrium; Acidosis; Adenosine Triphosphate; Alanine; Ammonia; Animals; Aspartic Acid; Bicarbonates; Dogs; Glutamine; Kidney; Kidney Cortex; Lactates; Lactic Acid; Phosphoenolpyruvate Carboxykinase (GTP) | 1986 |
Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport.
Topics: Amino Acids; Animals; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Citric Acid Cycle; Culture Techniques; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Glycogen; Humans; Ketones; Kidney; Kidney Tubules, Proximal; Lactates; Lactic Acid; Lipid Metabolism; Oxidation-Reduction; Perfusion; Pyruvates; Pyruvic Acid | 1985 |
Enteral nutrition as primary therapy in short bowel syndrome.
Topics: Acidosis; Adaptation, Physiological; Animals; Enteral Nutrition; Food, Formulated; Glutamine; Humans; Intestines; Lactates; Lactic Acid; Prognosis; Rats; Short Bowel Syndrome | 1994 |
Modelling hybridoma cell growth and metabolism--a comparison of selected models and data.
Topics: Ammonia; Animals; Antibodies, Monoclonal; Biotechnology; Cell Death; Cell Division; Cells, Cultured; Glucose; Glutamine; Humans; Hybridomas; Kinetics; Lactic Acid; Models, Biological | 1996 |
Proton magnetic resonance spectroscopic evaluation of brain tumor metabolism.
Topics: Alanine; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Glioma; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Phosphocreatine | 2004 |
Mechanisms of ammonia-induced astrocyte swelling.
Topics: Ammonia; Animals; Aquaporins; Astrocytes; Cell Size; Glutamine; Glutathione; Humans; Lactic Acid; Mitochondria; Neurotransmitter Agents; Oxidative Stress; Permeability; Receptors, GABA-A; Steroids | 2005 |
Amino acid catabolic pathways of lactic acid bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Biodegradation, Environmental; Fermentation; Food Microbiology; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Histidine; Lactic Acid; Lactobacillus; Proline | 2006 |
[Astrocytes in health and disease].
Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Injuries; Calcium; Cerebrospinal Fluid; Cerebrovascular Circulation; Extracellular Fluid; Free Radical Scavengers; Glutamine; Glutathione; Humans; Lactic Acid; Neurons; Neurotransmitter Agents; Receptors, Glutamate; Water-Electrolyte Balance | 2007 |
The role of the lymphoid system in the regulation of the blood glucose level.
Topics: Aspartic Acid; Blood Glucose; Eating; Glutamine; Humans; Lactic Acid; Lymphatic System; Metabolic Networks and Pathways; Models, Biological; Postprandial Period | 2007 |
Human fetal brain chemistry as detected by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Fetus; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Protons; Pyruvic Acid | 2009 |
Metabolic flux analysis in mammalian cell culture.
Topics: Amino Acids; Ammonia; Animals; Bioreactors; Carbon Isotopes; Cell Culture Techniques; CHO Cells; Cricetinae; Cricetulus; Glucose; Glutamine; Lactic Acid; Mammals; Models, Biological | 2010 |
Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells.
Topics: Adaptation, Biological; Cell Hypoxia; Cell Proliferation; Energy Metabolism; Gene Expression Regulation; Genes, myc; Glucose; Glutamine; Humans; Lactic Acid; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phosphatidylinositol 3-Kinase; Protein Serine-Threonine Kinases; Pyruvic Acid | 2011 |
Cancer metabolism: what we can learn from proteomic analysis by mass spectrometry.
Topics: Energy Metabolism; Glutamine; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lysosomes; Mass Spectrometry; Metabolomics; Neoplasms; Oxidative Stress; Proteomics; Pyruvate Kinase; Reactive Oxygen Species | 2012 |
Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force.
Topics: Angiogenesis Inhibitors; Endothelial Cells; Endothelium, Vascular; Glucose; Glutamine; Glycolysis; Humans; Hypoxia; Lactic Acid; Neoplasms; Neovascularization, Pathologic; Oxidation-Reduction | 2013 |
Metabolic flux rewiring in mammalian cell cultures.
Topics: Animals; Cell Culture Techniques; Cells; Glucose; Glutamine; Glycolysis; Humans; Lactic Acid; Metabolic Engineering; Metabolic Flux Analysis; Oxidative Phosphorylation | 2013 |
Magnetic resonance of the brain in chronic and acute liver failure.
Topics: Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Edema; Choline; Creatine; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Lactic Acid; Liver Failure; Liver Failure, Acute; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neuroimaging | 2014 |
Cancer metabolism and mass spectrometry-based proteomics.
Topics: Animals; Cell Hypoxia; Glioblastoma; Glutamine; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Mass Spectrometry; Mice; Oxidative Stress; Pancreatic Neoplasms; Protein Processing, Post-Translational; Proteomics; Pyruvate Kinase | 2015 |
Cancer metabolism: a therapeutic perspective.
Topics: Acetyl Coenzyme A; Adaptation, Physiological; Amino Acids; Antineoplastic Agents; Antioxidants; Autophagy; Blood Glucose; Energy Metabolism; Epigenomics; Fatty Acids; Genetic Heterogeneity; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Lipids; Mitochondria; Mitochondrial Ribosomes; Neoplasms; Nucleic Acids; Oxidative Stress; Pyruvic Acid; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Microenvironment | 2017 |
Multifactorial Effects on Different Types of Brain Cells Contribute to Ammonia Toxicity.
Topics: Ammonia; Animals; Astrocytes; Brain; Cyclic GMP; Energy Metabolism; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Lactic Acid; Liver Failure, Acute; Potassium; Pyruvic Acid; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 2 | 2017 |
The use of magnetic resonance spectroscopy for assessing the effect of diet on cognition.
Topics: Aspartic Acid; Brain; Choline; Cognition; Creatine; Diet; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Neurotransmitter Agents; Taurine | 2018 |
Magnetic resonance spectroscopy and magnetic resonance spectroscopic imaging in Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy: A literature review.
Topics: Aspartic Acid; Brain; CADASIL; Creatine; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Proton Magnetic Resonance Spectroscopy | 2017 |
Targeting cancer metabolism through synthetic lethality-based combinatorial treatment strategies.
Topics: Amino Acid Transport System ASC; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Glucose; Glucose Transport Proteins, Facilitative; Glutaminase; Glutamine; Humans; Lactic Acid; Minor Histocompatibility Antigens; Molecular Targeted Therapy; Monocarboxylic Acid Transporters; Neoplasms; Pyruvate Dehydrogenase Complex | 2018 |
Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance.
Topics: Amino Acids; Animals; Citric Acid Cycle; Dimerization; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Glucose; Glutamine; Humans; Hypoxia; Lactic Acid; Mice; Mitochondria; Neoplasms; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen; Phenotype; Reactive Oxygen Species; Tumor Microenvironment | 2020 |
The metabolism of cancer cells during metastasis.
Topics: Acetates; Adenosine Triphosphate; Animals; Cell Plasticity; Fatty Acids; Glutamine; Humans; Lactic Acid; Neoplasm Metastasis; Neoplasms; Neoplastic Cells, Circulating; Pyruvic Acid | 2021 |
Inhibition of glutaminolysis in combination with other therapies to improve cancer treatment.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Citric Acid Cycle; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glutaminase; Glutamine; Glycogen; Humans; Ketoglutaric Acids; Lactic Acid; Signal Transduction | 2021 |
Metabolic reservoir cycles in cancer.
Topics: Glutamic Acid; Glutamine; Glycogen; Humans; Lactic Acid; Neoplasms; Triglycerides | 2022 |
29 trial(s) available for lactic acid and glutamine
| Article | Year |
|---|---|
Growth hormone suppression and glutamine flux associated with cardiac surgery.
Topics: Blood Glucose; Blood Pressure; Coronary Artery Bypass; Fatty Acids, Nonesterified; Female; Glutamic Acid; Glutamine; Growth Hormone; Humans; Hydrocortisone; Insulin; Lactates; Lactic Acid; Male; Middle Aged; Muscle, Skeletal; Somatostatin | 1994 |
Hyperammonaemia in relation to high-intensity exercise duration in man.
Topics: Adenine Nucleotides; Adult; Ammonia; Exercise; Female; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Muscle, Skeletal | 1994 |
Effect of low- and high-carbohydrate diets on the plasma glutamine and circulating leukocyte responses to exercise.
Topics: 3-Hydroxybutyric Acid; Adult; Cohort Studies; Dietary Carbohydrates; Exercise; Food, Formulated; Glutamine; Humans; Hydrocortisone; Hydroxybutyrates; Lactic Acid; Leukocyte Count; Leukocytes; Lymphocyte Count; Male; Neutrophils | 1998 |
Influence of carbohydrate status on immune responses before and after endurance exercise.
Topics: Adult; Blood Glucose; Diet; Dietary Carbohydrates; Exercise; Glutamine; Glycogen; Humans; Hydrocortisone; Immunity, Cellular; Lactic Acid; Leukocyte Count; Lymphocyte Activation; Lymphocyte Count; Male; Oxygen Consumption; Physical Endurance; Time Factors | 1998 |
Effects of exercise intensity, duration and recovery on in vitro neutrophil function in male athletes.
Topics: Adult; Exercise; Exercise Test; Glutamine; Humans; Lactic Acid; Leukocyte Count; Male; Neutrophils; Oxygen Consumption; Pancreatic Elastase; Sports | 1999 |
Effects of taurine on human embryo development in vitro.
Topics: Blastocyst; Cell Count; Cell Death; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Glutamine; Humans; Lactic Acid; Pyruvic Acid; Taurine | 1999 |
The effect of dopexamine on regional tissue oxygenation, systemic inflammation and amino acid exchange in major abdominal surgery.
Topics: Abdomen; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Anti-Inflammatory Agents; Dopamine; Glutamine; Hemodynamics; Humans; Inflammation Mediators; Interleukin-6; Lactic Acid; Middle Aged; Oxygen; Oxygen Consumption; Splanchnic Circulation; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2000 |
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; Dipeptides; Epilepsy; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Phantoms, Imaging; Regression Analysis; Sensitivity and Specificity | 2000 |
Aging alters regional multichemical profile of the human brain: an in vivo 1H-MRS study of young versus middle-aged subjects.
Topics: Adult; Age Factors; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reference Values | 2001 |
Aging alters the multichemical networking profile of the human brain: an in vivo (1)H-MRS study of young versus middle-aged subjects.
Topics: Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Net; Organ Specificity | 2001 |
BCAA intake affects protein metabolism in muscle after but not during exercise in humans.
Topics: Administration, Oral; Adult; Arteries; Biopsy; Blood Flow Velocity; Exercise Test; Glutamine; Glycogen; Growth Hormone; Heart Rate; Humans; Insulin; Isoleucine; Lactic Acid; Leucine; Male; Muscle, Skeletal; Norepinephrine; Oxygen Consumption; Phenylalanine; Physical Exertion; Proteins; Pulmonary Gas Exchange; Tyrosine; Valine | 2001 |
Carbohydrate supplementation during intense exercise and the immune response of cyclists.
Topics: Adult; Analysis of Variance; Antibody Formation; Blood Glucose; Cross-Over Studies; Cytokines; Dietary Carbohydrates; Dietary Supplements; Exercise; Exercise Test; Glutamine; Humans; Hydrocortisone; Insulin; Lactic Acid; Male; Sweat; Weight Loss | 2002 |
A randomized, controlled trial of parenteral glutamine in ill, very low birth-weight neonates.
Topics: Amino Acids; Ammonia; Birth Weight; Enteral Nutrition; Female; Gestational Age; Glutamine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Lactic Acid; Liver Function Tests; Male; Parenteral Nutrition; Pyruvic Acid; Risk Factors; Time Factors; Urea | 2003 |
Effects on skeletal muscle of intravenous glutamine supplementation to ICU patients.
Topics: Adult; Aged; Aged, 80 and over; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Critical Care; Dose-Response Relationship, Drug; Female; Glutamine; Humans; Infusions, Intravenous; Intensive Care Units; Lactic Acid; Male; Middle Aged; Muscle, Skeletal; Nitrogen; Prospective Studies; Single-Blind Method; Sulfhydryl Compounds; Treatment Outcome | 2004 |
Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder.
Topics: Adult; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Brain; Brain Chemistry; Brain Mapping; Case-Control Studies; Echo-Planar Imaging; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Lactic Acid; Lithium; Magnetic Resonance Spectroscopy; Male; Psychiatric Status Rating Scales; Valproic Acid | 2004 |
Effects on skeletal muscle glutathione status of ischemia and reperfusion following abdominal aortic aneurysm surgery.
Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Elective Surgical Procedures; Female; Glutamine; Glutathione; Humans; Ischemia; Lactic Acid; Leg; Male; Muscle, Skeletal; Phosphocreatine; Reperfusion; Time Factors | 2006 |
[Effect of total parenteral nutrition with supplementation of glutamine on the plasma diamine oxidase activity and D-lactate content in patients with multiple organ dysfunction syndrome].
Topics: Adult; Aged; Amine Oxidase (Copper-Containing); Female; Glutamine; Humans; Lactic Acid; Male; Middle Aged; Multiple Organ Failure; Parenteral Nutrition, Total; Prognosis | 2006 |
Effects of glutamine and hyperoxia on pulmonary oxygen uptake and muscle deoxygenation kinetics.
Topics: Administration, Oral; Adult; Beverages; Bicycling; Energy Metabolism; Exercise; Glutamine; Hemoglobins; Humans; Hyperoxia; Kinetics; Lactic Acid; Male; Muscle, Skeletal; Oxygen; Oxygen Consumption; Pulmonary Gas Exchange; Single-Blind Method; Spectroscopy, Near-Infrared; Tricarboxylic Acids | 2007 |
Effect of glutamine in patients with esophagus resection.
Topics: Adult; Aged; Blood Proteins; C-Reactive Protein; Calcitonin; Calcitonin Gene-Related Peptide; Double-Blind Method; Esophagectomy; Female; Follow-Up Studies; Glutamine; Glycoproteins; Humans; Interleukin-6; Interleukin-8; Lactic Acid; Lymphocyte Count; Male; Middle Aged; Placebos; Postoperative Complications; Prealbumin; Premedication; Prospective Studies; Protein Precursors; Retinol-Binding Proteins; Serum Albumin; Survival Rate; Systemic Inflammatory Response Syndrome; Transferrin; Tumor Necrosis Factor-alpha | 2010 |
A search for biomarkers as diagnostic tools for food allergy: a pilot study in peanut-allergic patients.
Topics: Adolescent; Adult; Allergens; Arachis; Biomarkers; Creatinine; Discriminant Analysis; Female; Glutamine; Humans; Immunoglobulin E; Lactic Acid; Lipids; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Niacin; Peanut Hypersensitivity; Pilot Projects; Principal Component Analysis; Saliva; Signal Processing, Computer-Assisted; Tryptophan; Tyrosine; Young Adult | 2011 |
[Effects of rhubarb on the intestinal barrier function of patients with acute myocardial infarction-heart].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Endotoxins; Female; Glutamine; Heart Failure; Humans; Interleukin-10; Lactic Acid; Male; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Pantoprazole; Peptide Fragments; Proton Pump Inhibitors; Rheum; Tumor Necrosis Factor-alpha | 2012 |
Systemic metabolic markers and myocardial glucose uptake in type 2 diabetic and coronary artery disease patients treated for 16 weeks with rosiglitazone, a PPARγ agonist.
Topics: Aged; Blood Glucose; Coronary Artery Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glutamine; Humans; Hypoglycemic Agents; Lactic Acid; Lipoproteins; Male; Middle Aged; Myocardium; PPAR gamma; Rosiglitazone; Thiazolidinediones; Time Factors | 2014 |
[Effects of glutamine combined with ulinastatin on inflammatory response of patients with severe burn injury].
Topics: Adolescent; Adult; Burns; Female; Glutamine; Glycoproteins; Humans; Interleukin-6; Lactic Acid; Lipopolysaccharides; Male; Tumor Necrosis Factor-alpha; Wound Healing; Young Adult | 2013 |
[Effects of Couplet Medicines (Astragalus Membranaceus and Jiaozhen) on Intestinal Barrier in Postoperative Colorectal Cancer Patients].
Topics: Amine Oxidase (Copper-Containing); Antineoplastic Combined Chemotherapy Protocols; Astragalus propinquus; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drugs, Chinese Herbal; Glutamine; Humans; Intestinal Mucosa; Intestines; Lactic Acid; Tumor Necrosis Factor-alpha | 2015 |
Acute Citrulline-Malate Supplementation and High-Intensity Cycling Performance.
Topics: Acid-Base Equilibrium; Adult; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Exercise; Exercise Test; Glutamine; Heart Rate; Humans; Lactic Acid; Malates; Male; Ornithine; Physical Endurance; Young Adult | 2016 |
Anaplerotic therapy in propionic acidemia.
Topics: Amino Acids; Ammonia; Carbon-Carbon Ligases; Child; Child, Preschool; Citrates; Citric Acid; Citric Acid Cycle; Dietary Supplements; Female; Glutamine; Humans; Lactic Acid; Male; Ornithine; Propionic Acidemia; Treatment Outcome | 2017 |
Carbohydrate and Glutamine Supplementation Attenuates the Increase in Rating of Perceived Exertion during Intense Exercise in Hypoxia Similar to 4200 m.
Topics: Adult; Altitude; Altitude Sickness; Blood Gas Analysis; Dietary Carbohydrates; Dietary Supplements; Double-Blind Method; Glutamine; Healthy Volunteers; Heart Rate; Humans; Lactic Acid; Male; Oxygen Consumption; Perception; Physical Exertion; Polysaccharides; Running; Time Factors | 2020 |
Glutamine relieves the hypermetabolic response and reduces organ damage in severe burn patients: A multicenter, randomized controlled clinical trial.
Topics: Adult; Amine Oxidase (Copper-Containing); Amino Acids, Essential; Burns; Catecholamines; Glucagon; Glutamine; Humans; Hydroxybutyrate Dehydrogenase; L-Lactate Dehydrogenase; Lactic Acid; Lactulose; Mannitol; Single-Blind Method; Troponin | 2022 |
Myocardial Protecting Role of Glutamine in Patients with Low Ejection Fraction Undergoing Elective On-Pump Coronary Artery Bypass Graft Surgery.
Topics: Coronary Artery Bypass; Glutamine; Humans; Lactic Acid; Myocardium; Saline Solution; Stroke Volume; Troponin I | 2022 |
381 other study(ies) available for lactic acid and glutamine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Fuel selection and the production of ammonium by the kidney: studies using insulin.
Topics: Acidosis; Ammonia; Ammonium Chloride; Animals; Dogs; Fatty Acids; Female; Glutamine; Insulin; Kidney; Lactates; Lactic Acid; Male; Oxidation-Reduction; Oxygen Consumption | 1992 |
Energy metabolism of the human fallopian tube.
Topics: Acetoacetates; Culture Techniques; Energy Metabolism; Fallopian Tubes; Female; Glucose; Glutamine; Hexokinase; Humans; Ketoglutarate Dehydrogenase Complex; Lactates; Lactic Acid; Oxygen Consumption; Phosphofructokinase-2; Phosphorylases; Phosphotransferases | 1992 |
Altered glutamine metabolism in rat portal drained viscera and hindquarter during hyperammonemia.
Topics: Amino Acids; Ammonia; Analysis of Variance; Animals; Blood Glucose; Glutamates; Glutamic Acid; Glutamine; Hindlimb; Intestinal Mucosa; Ischemia; Lactates; Lactic Acid; Liver; Male; Muscle Contraction; Muscles; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Regional Blood Flow; Urea; Viscera | 1992 |
Glutamine and glucose metabolism in bovine blood lymphocytes.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Blood Glucose; Cattle; Glutamates; Glutamic Acid; Glutamine; Humans; In Vitro Techniques; Lactates; Lactic Acid; Lymphocytes; Male; Pyruvates; Pyruvic Acid; Rats | 1992 |
Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor. 2. Effects of medium components and waste products.
Topics: Ammonia; Animals; Asparagine; Cell Division; Cell Line; Cells, Cultured; Cricetinae; Female; Glucose; Glutamine; Kinetics; Lactates; Lactic Acid; Ovary; Oxidation-Reduction | 1990 |
Studies on monoclonal antibody production by a hybridoma cell line (C1E3) immobilised in a fixed bed, porosphere culture system.
Topics: Ammonia; Animals; Antibodies, Monoclonal; Cell Count; Cell Division; Cell Line; Cell Survival; Cytological Techniques; Glass; Glucose; Glutamine; Hybridomas; Kinetics; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mice; Oxygen | 1990 |
The protective effect of serum against hydrodynamic damage of hybridoma cells in agitated and surface-aerated bioreactors.
Topics: Animals; Antigens; Blood; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytological Techniques; Glucose; Glutamine; Hepatitis B Surface Antigens; Hybridomas; Kinetics; Lactates; Lactic Acid; Mice; Physical Phenomena; Physics | 1990 |
Growth and product inhibition kinetics of T-cell hybridomas producing lymphokines in batch and continuous culture.
Topics: Ammonia; Animals; Cell Division; Cell Line; Gene Expression Regulation; Glucose; Glutamine; Hybridomas; Kinetics; Lactates; Lactic Acid; Lymphokines; Methods; Mice; T-Lymphocytes | 1990 |
Transient behavior of T-cell hybridomas in response to changes in metabolite concentrations in continuous culture.
Topics: Ammonia; Animals; Cell Division; Cell Line; Glucose; Glutamine; Hybridomas; Lactates; Lactic Acid; Lymphokines; Mice; T-Lymphocytes | 1990 |
Chinese hamster ovary cell growth and interferon production kinetics in stirred batch culture.
Topics: Ammonia; Animals; Asparagine; Cell Division; Cells, Cultured; Cricetinae; Cricetulus; Female; Glucose; Glutamine; Interferon-gamma; Kinetics; Lactates; Lactic Acid; Ovary | 1991 |
Enzyme sensor-FIA-system for on-line monitoring of glucose, lactate and glutamine in animal cell cultures.
Topics: Animals; Biosensing Techniques; Calibration; Cells, Cultured; Glucose; Glutamine; Interleukin-2; Lactates; Lactic Acid; Mice; Online Systems; Rats | 1991 |
Growth study of lactate and ammonia double-resistant clones of HL-60 cells.
Topics: Ammonium Chloride; Cell Division; Clone Cells; Drug Resistance; Glucose; Glutamine; Humans; Kinetics; Lactates; Lactic Acid; Leukemia; Tumor Cells, Cultured | 1992 |
Design and performance of a trickle-bed bioreactor with immobilized hybridoma cells.
Topics: Alanine; Aluminum Silicates; Ammonia; Biotechnology; Cell Count; Cell Division; Cell Line; Cell Survival; Culture Media; Equipment Design; Glucose; Glutamine; Hybridomas; Lactates; Lactic Acid; Polyurethanes | 1992 |
Comparison of specific rates of hybridoma growth and metabolism in batch and continuous cultures.
Topics: Ammonia; Animals; Antibody Formation; Cell Division; Culture Media; Culture Techniques; Glucose; Glutamine; Hybridomas; Lactates; Lactic Acid; Mice; Mice, Inbred BALB C | 1992 |
Hepatic adaptations to iron deficiency and exercise training.
Topics: Adaptation, Physiological; Alanine; Animals; Exercise Test; Female; Glutamine; Hemoglobins; Iron Deficiencies; Lactates; Lactic Acid; Liver; Mitochondria, Liver; Organ Size; Oxidation-Reduction; Physical Conditioning, Animal; Pyruvates; Rats; Rats, Sprague-Dawley | 1992 |
Glutamine is a good substrate for glycogen synthesis in isolated hepatocytes from 72 h-starved rats, but not from 24 h- or 48 h-starved rats.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Gluconeogenesis; Glucose; Glutamine; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Rats; Rats, Wistar; Starvation; Stimulation, Chemical; Substrate Specificity; Time Factors | 1992 |
The use of in vivo proton NMR to study the effects of hyperammonemia in the rat cerebral cortex.
Topics: Ammonia; Animals; Cerebral Cortex; Choline; Glutamates; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains | 1991 |
Remnant kidney metabolism in the dog.
Topics: Ammonia; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Kidney; Lactates; Lactic Acid; Ligation; Nephrectomy; Nephrons; Oxygen Consumption; Renal Veins | 1991 |
Coupling effects in volume selective 1H spectroscopy of major brain metabolites.
Topics: Aspartic Acid; Brain Chemistry; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Inositol; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy | 1991 |
Intermediary metabolism in renal proximal tubules in the recovery phase of experimental renal ischemia in dogs.
Topics: Alanine; Ammonia; Analysis of Variance; Animals; Dogs; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Ischemia; Ketoglutaric Acids; Kidney; Kidney Tubules, Proximal; Lactates; Lactic Acid; Oxygen Consumption; Rats | 1991 |
Reduction in lactate accumulation correlates with differentiation-induced terminal cell division of leukemia cells.
Topics: Acetamides; Animals; Carbon Dioxide; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Dexamethasone; Dimethyl Sulfoxide; Glutamates; Glutamic Acid; Glutamine; Glycolysis; Humans; Lactates; Lactic Acid; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Mice | 1991 |
Propagation of a mouse myeloma cell line J558L producing human CD4 immunoglobulin G1.
Topics: Amino Acids; Ammonia; Animals; Antiviral Agents; CD4 Antigens; Cell Division; Cell Line; Chromatography; Electrophoresis, Polyacrylamide Gel; Glucose; Glutamine; Immunoglobulin gamma-Chains; Immunoglobulin Heavy Chains; In Vitro Techniques; Insulin; Isoelectric Focusing; Lactates; Lactic Acid; Mice; Multiple Myeloma; Recombinant Fusion Proteins; Transfection; Transferrin | 1992 |
Glucose and glutamine metabolism in rat macrophages: enhanced glycolysis and unaltered glutaminolysis in spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Female; Glucose; Glutamates; Glutamine; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Macrophages; Pentose Phosphate Pathway; Peritoneal Cavity; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred BB | 1991 |
[Metabolic changes in patients with hereditary fructose intolerance. A contribution to the topic of fructose administration for parenteral feeding].
Topics: Adult; Ammonia; Blood Glucose; Female; Fructose; Fructose Intolerance; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Parenteral Nutrition; Phosphates; Uric Acid | 1991 |
Hepatic insufficiency and increased proteolysis, cardiac output, and oxygen consumption following hemorrhage.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Cardiac Output; Dogs; Endopeptidases; Glutamine; Hemodynamics; Hemorrhage; Lactates; Lactic Acid; Liver; Methylhistidines; Oxygen Consumption; Urea | 1991 |
Relationship of plasma amino acids to oxygen debt during hemorrhagic shock.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Pressure; Cardiac Output; Dogs; Glutamine; Lactates; Lactic Acid; Male; Oxygen Consumption; Shock, Hemorrhagic | 1991 |
Regulation of acid-base state with hemofiltration in circulatory shock in patients after open heart surgery.
Topics: Acid-Base Imbalance; Ammonia; Bicarbonates; Cardiac Surgical Procedures; Glutamine; Hemofiltration; Humans; Lactates; Lactic Acid; Postoperative Care; Shock, Cardiogenic | 1991 |
Glutamine and glucose metabolism in thymocytes from normal and spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Animals; Cell Count; Diabetes Mellitus, Experimental; Female; Glucose; Glutamine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred BB; T-Lymphocytes | 1991 |
Glutamine and fatty acid oxidation are the main sources of energy for Kupffer and endothelial cells.
Topics: Animals; Cell Separation; Endothelium; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Kupffer Cells; Lactates; Lactic Acid; Liver; Oxidation-Reduction; Palmitates | 1991 |
Energy substrate requirements for in-vitro development of hamster 1- and 2-cell embryos to the blastocyst stage.
Topics: Amino Acids; Animals; Blastocyst; Cleavage Stage, Ovum; Cricetinae; Culture Media; Culture Techniques; Dose-Response Relationship, Drug; Energy Metabolism; Glutamine; Lactates; Lactic Acid; Morula; Pyruvates; Pyruvic Acid | 1991 |
Substrate and pH effects on glutamine synthesis in rat liver. Consequences for acid-base regulation.
Topics: Acid-Base Equilibrium; Ammonia; Ammonium Chloride; Animals; Glucose; Glutamine; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Male; Nitrogen; Ornithine; Portal Vein; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
Adaptation to non-ammoniagenic medium and selective substrate feeding lead to enhanced yields in animal cell cultures.
Topics: Adaptation, Physiological; Amino Acids; Ammonia; Animals; Cell Division; Cell Line; Culture Media; Energy Metabolism; Glucose; Glutamates; Glutamic Acid; Glutamine; Ketoglutaric Acids; Lactates; Lactic Acid | 1990 |
Maximal activity of phosphate-dependent glutaminase and glutamine metabolism in septic rats.
Topics: Alanine; Animals; Arteries; Glutaminase; Glutamine; Intestinal Mucosa; Kidney; Lactates; Lactic Acid; Liver; Lymph Nodes; Lymphocytes; Male; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sepsis; Veins | 1991 |
The role of amino acids in the energy generating pathways of Litomosoides carinii.
Topics: Acetates; Alanine; Ammonia; Animals; Antimetabolites; Carbon Dioxide; Energy Metabolism; Female; Filarioidea; Glucose; Glutamine; Isoxazoles; Lactates; Lactic Acid; Rats | 1990 |
Comparison of various methods for monitoring hybridoma cell proliferation.
Topics: Amino Acids; Ammonia; Animals; Cell Count; Cell Division; Cell Survival; Culture Media; DNA; Electrophoresis, Agar Gel; Flow Cytometry; Glucose; Glutamine; Hybridomas; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Mice; Spectrometry, Fluorescence; Time Factors | 1990 |
Carbohydrate utilization in exercising muscle in subtotally nephrectomized rabbits.
Topics: Alanine; Animals; Carbohydrate Metabolism; Glutamine; Glycogen; Ketoglutaric Acids; Kidney; Kidney Failure, Chronic; Lactates; Lactic Acid; Muscles; Nephrectomy; Physical Exertion; Pyruvates; Pyruvic Acid; Rabbits | 1990 |
Effects of acute hyperammonemia on cerebral amino acid metabolism and pHi in vivo, measured by 1H and 31P nuclear magnetic resonance.
Topics: Acetates; Ammonia; Animals; Brain; Energy Metabolism; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Nucleotides; Phosphocreatine; Phosphorus; Protons; Rats; Rats, Inbred Strains | 1989 |
Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study.
Topics: Acute Disease; Animals; Biomarkers; Brain; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Lactates; Lactic Acid; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Phosphorus; Rats; Rats, Inbred Strains | 1989 |
End products of glutamine oxidation in MC-29 virus-induced chicken hepatoma mitochondria.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Citric Acid Cycle; Glutamates; Glutamic Acid; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Pharmacologic modulation of increased release of gluconeogenic precursors from extra-splanchnic organs in sepsis.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Cycloserine; Dichloroacetic Acid; Gluconeogenesis; Glutamate-Ammonia Ligase; Glutamine; Hepatectomy; Intestine, Small; Lactates; Lactic Acid; Liver; Male; Methionine Sulfoximine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Sepsis | 1989 |
Stimulation of glutamine metabolism by the antiepileptic drug, sodium valproate, in isolated dog kidney tubules.
Topics: Alanine; Ammonia; Animals; Aspartic Acid; Dogs; Female; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Kidney Tubules; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Valproic Acid | 1989 |
Comparison of glycolysis and glutaminolysis in Onchocerca volvulus and Brugia pahangi by 13C nuclear magnetic resonance spectroscopy.
Topics: Animals; Brugia; Glutamine; Glycolysis; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Onchocerca; Succinates; Succinic Acid | 1989 |
Role of extra-splanchnic organs in the metabolic response to sepsis: effect of insulin.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Glutamine; Hepatectomy; Insulin; Intestine, Small; Kinetics; Lactates; Lactic Acid; Liver; Male; Rats; Rats, Inbred Strains; Sepsis | 1989 |
Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.
Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Cysts; Diagnosis, Differential; Female; Glioma; Glutamine; Humans; Inositol; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neurilemmoma; Phosphocreatine | 1989 |
Glycolysis and glutaminolysis in perifused Ehrlich ascites tumour cells.
Topics: Ammonia; Animals; Carcinoma, Ehrlich Tumor; Female; Glucose; Glutamine; Glycolysis; Lactates; Lactic Acid; Mice | 1989 |
Effects of hyperthermia on the peripheral metabolism of ammonia and glutamine.
Topics: Acid-Base Equilibrium; Alanine; Ammonia; Arteries; Blood Glucose; Body Temperature; Fatty Acids, Nonesterified; Female; Fever; Forearm; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Crabtree effect in tumoral pancreatic islet cells.
Topics: Adenine Nucleotides; Adenoma, Islet Cell; Animals; Glucose; Glutamine; Lactates; Lactic Acid; Lipids; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Pancreatic Neoplasms; Tumor Cells, Cultured | 1988 |
Substrate specificity to maintain cellular ATP along the mouse nephron.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Anaerobiosis; Animals; Glucose; Glutamine; Hydroxybutyrates; Indicators and Reagents; Ionophores; Kidney Tubules, Proximal; Kinetics; Lactates; Lactic Acid; Loop of Henle; Male; Mice; Mice, Inbred ICR; Microbial Collagenase; Nephrons; Ouabain | 1988 |
Effect of hypoglycemic encephalopathy upon amino acids, high-energy phosphates, and pHi in the rat brain in vivo: detection by sequential 1H and 31P NMR spectroscopy.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Electroencephalography; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Hypoglycemia; Insulin; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Nucleotides; Phosphates; Phosphocreatine; Rats | 1985 |
Ammonia intoxication: effects on cerebral cortex and spinal cord.
Topics: Acetates; Ammonia; Animals; Blood; Carbon Dioxide; Cats; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Spinal Cord | 1985 |
Renal tubular biochemistry during acute and chronic metabolic alkalosis in the dog.
Topics: Acute Disease; Alkalosis; Ammonia; Animals; Chronic Disease; Citrates; Citric Acid; Cytosol; Dogs; Gluconeogenesis; Glutamates; Glutamic Acid; Glutamine; Ketoglutaric Acids; Kidney Tubules; Lactates; Lactic Acid; Malates; Mitochondria; Potassium | 1985 |
Effects of nicardipine on coronary blood flow, left ventricular inotropic state and myocardial metabolism in patients with angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Circulation; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Norepinephrine; Oxygen Consumption | 1985 |
The metabolic response of the kidney to acute sodium lactate alkalosis.
Topics: Alanine; Alanine Transaminase; Alkalosis; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Kidney; Kidney Cortex; Lactates; Lactic Acid; Liver; Muscles; Pyruvates; Pyruvic Acid | 1985 |
Muscle ammonia metabolism during isometric contraction in humans.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adolescent; Adult; Alanine; Ammonia; AMP Deaminase; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Isometric Contraction; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles | 1986 |
Glutamine metabolism in isolated incubated adipocytes of the rat.
Topics: Adipose Tissue; Alanine; Ammonia; Animals; Glucose; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Insulin; Isoproterenol; Lactates; Lactic Acid; Male; Obesity; Rats; Rats, Zucker; Triglycerides | 1988 |
Pathways for organic osmolyte synthesis in rabbit renal papillary tissue, a metabolic study using 13C-labeled substrates.
Topics: Alanine; Aldehyde Reductase; Animals; Citric Acid Cycle; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Glycolysis; Inositol; Kidney Medulla; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rabbits; Sorbitol | 1988 |
Subcellular distribution of malate-aspartate cycle intermediates during normoxia and anoxia in the heart.
Topics: Adenine Nucleotides; Anaerobiosis; Animals; Aspartic Acid; Citrates; Citric Acid; Citric Acid Cycle; Cytosol; Glutamates; Glutamic Acid; Glutamine; Ketoglutaric Acids; Lactates; Lactic Acid; Malates; Male; Mitochondria, Heart; Myocardium; Oxygen; Phosphocreatine; Rats; Rats, Inbred Strains; Subcellular Fractions | 1988 |
Effects of oxygen deprivation on incubated rat soleus muscle.
Topics: Adenine Nucleotides; Alanine; Animals; Energy Metabolism; Glutamine; Kinetics; Lactates; Lactic Acid; Male; Muscle Proteins; Muscles; Nucleosides; Oxygen; Phosphocreatine; Rats | 1989 |
Comparative effect of ANF and various diuretics on isolated nephron segments.
Topics: Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Diuretics; Dogs; Glutamine; In Vitro Techniques; Kidney Tubules, Collecting; Kidney Tubules, Proximal; Lactates; Lactic Acid; Nephrons; Oxygen Consumption; Rats | 1987 |
The coupling of metabolic to secretory events in pancreatic islets. The possible role of glutathione reductase.
Topics: Animals; Calcium; Carmustine; Cyclic AMP; Glutamine; Glutathione; Glutathione Reductase; Insulin; Islets of Langerhans; Lactates; Lactic Acid; Leucine; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1985 |
Substrate utilization for lactate and energy production by heat-shocked L929 cells.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Cell Line; Citric Acid Cycle; Energy Metabolism; Fibroblasts; Glucose; Glutamine; Heat-Shock Proteins; Lactates; Lactic Acid; Mice; NAD; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid; Temperature | 1986 |
Acidotic alterations in oxidative metabolism influencing rat renal slice ammoniagenesis.
Topics: Acidosis; Ammonia; Animals; Carbon Dioxide; Gluconeogenesis; Glutamine; Kidney; Kinetics; Lactates; Lactic Acid; Male; Oxidation-Reduction; Oxygen Consumption; Rats | 1987 |
Stimulation of glycogen synthesis and lipogenesis by glutamine in isolated rat hepatocytes.
Topics: Animals; Carbohydrate Metabolism; Dose-Response Relationship, Drug; Glucagon; Glucose; Glutamine; Glycogen Synthase; In Vitro Techniques; Lactates; Lactic Acid; Lipids; Liver; Liver Glycogen; Male; Purines; Rats; Rats, Inbred Strains; Stimulation, Chemical; Vasopressins | 1987 |
Glutamine is responsible for stimulating glycolysis by L929 cells.
Topics: Animals; Energy Metabolism; Glutamine; Glycolysis; Insulin; L Cells; Lactates; Lactic Acid; Mice; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1986 |
Studies on the mechanism by which glutamine and heat shock increase lactate synthesis by L929 cells in the presence of insulin.
Topics: 3-O-Methylglucose; Aminooxyacetic Acid; Cell Line; Deoxyglucose; Glutamine; Glycolysis; Hot Temperature; Insulin; Kinetics; Lactates; Lactic Acid; Methylglucosides; Pyruvates; Pyruvic Acid; Transaminases | 1986 |
Fuel-stimulated insulin secretion by clonal hamster beta-cell line HIT T-15.
Topics: 3-O-Methylglucose; Animals; Cell Line; Cricetinae; Dihydroxyacetone; Energy Metabolism; Glucose; Glutamine; Hemiterpenes; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Lactates; Lactic Acid; Methylglucosides | 1987 |
Factors affecting monoclonal antibody production in culture.
Topics: Ammonia; Animals; Antibodies, Monoclonal; Biotechnology; Cell Division; Cells, Cultured; Culture Media; Glucose; Glutamine; Hybridomas; Lactates; Lactic Acid; Mice; Perfusion | 1987 |
Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Fatty Acids; Female; Glucose; Glutamine; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Macrophages; Mice; Mice, Inbred C57BL; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1987 |
Effect of acetazolamide on renal metabolism and ammoniagenesis in the dog.
Topics: Acetazolamide; Acidosis; Ammonium Chloride; Animals; Chronic Disease; Citrates; Citric Acid; Dogs; Glutamine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Tubules; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Renal Circulation | 1987 |
Interaction of metabolism of aspartate and inosine and energy state of malignant cells.
Topics: Adenosine Triphosphate; Animals; Asparagine; Aspartic Acid; Carcinoma, Ehrlich Tumor; Cells, Cultured; Energy Metabolism; Glutamine; Inosine; Lactates; Lactic Acid; Mice; Oxygen Consumption; Proline | 1987 |
Substrate oxidation in kidney slices from acidotic and alkalotic rats: role in ammoniagenic adaptation.
Topics: Acetates; Acidosis; Alkalosis; Ammonia; Animals; Glutamine; Ketoglutaric Acids; Kidney; Lactates; Lactic Acid; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains | 1987 |
ATP turnover and renal response of dog tubules to pH changes in vitro.
Topics: Adenosine Triphosphate; Ammonia; Animals; Culture Media; Dogs; Energy Metabolism; Glutamine; Hydrogen; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Tubules; Lactates; Lactic Acid; Oxygen Consumption; Serum Albumin | 1986 |
Effect of the blood lactate concentration on renal glutamine metabolism in dogs with chronic metabolic acidosis.
Topics: Acidosis; Adenosine Triphosphate; Animals; Carbon Dioxide; Citrates; Dogs; Female; Glutamine; Hydrogen-Ion Concentration; Kidney; Kinetics; Lactates; Lactic Acid; Male; Oxygen | 1985 |
Utilization of pyruvate and pyruvate precursors by normal and carcinogen-altered rat tracheal epithelial cells in culture.
Topics: Alanine; Animals; Carbon Radioisotopes; Cells, Cultured; Glucose; Glutamine; Glycolysis; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Trachea; Tracheal Neoplasms | 1986 |
Studies on the role of the liver and splanchnic tissues in the production of carbohydrate intolerance in uremia.
Topics: Alanine; Animals; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Humans; Kinetics; Lactates; Lactic Acid; Liver; Liver Glycogen; Nephrectomy; Portal Vein; Rats; Uremia | 1981 |
Effects of in vitro potassium on ammoniagenesis in rat and canine kidney tissue.
Topics: Acidosis; Ammonia; Animals; Carbon Dioxide; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kidney; Lactates; Lactic Acid; Male; Oxygen Consumption; Potassium; Rats; Rats, Inbred Strains | 1982 |
Lactate, alanine and glutamine metabolism in isolated canine pup liver cells.
Topics: Alanine; Ammonia; Animals; Dogs; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1983 |
The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis.
Topics: Alanine; Animals; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Lactates; Lactic Acid; Male; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Substrate Specificity | 1984 |
Regulation of glucose utilization in chick embryo fibroblasts by bicarbonate ion.
Topics: Animals; Bicarbonates; Cell Division; Cells, Cultured; Chick Embryo; Culture Media; Dose-Response Relationship, Drug; Fibroblasts; Glucose; Glutamine; Lactates; Lactic Acid; Sodium Bicarbonate | 1981 |
Simultaneous stimulation of uric acid synthesis and gluconeogenesis in chicken hepatocytes by alpha-adrenergic action of epinephrine and calcium.
Topics: Animals; Calcium; Chickens; Dihydroxyacetone; Epinephrine; Gluconeogenesis; Glucose; Glutamine; Lactates; Lactic Acid; Liver; Male; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Uric Acid | 1982 |
Effects of pyruvate on the growth of normal and transformed hamster embryo fibroblasts.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Glucose; Glutamine; Lactates; Lactic Acid; Polyomavirus; Pyruvates; Pyruvic Acid | 1982 |
Metabolism and transport of L-glutamine and L-alanine by renal tubules of chickens.
Topics: Acidosis, Respiratory; Alanine; Alkalosis, Respiratory; Animals; Biological Transport; Carbon Dioxide; Chickens; Disease Models, Animal; Glutamine; Hydrogen-Ion Concentration; Kidney Tubules; Lactates; Lactic Acid; Renal Circulation | 1983 |
Equilibration of metabolic CO2 with preformed CO2 and bicarbonate. An unexpected finding.
Topics: Alanine; Animals; Bicarbonates; Carbon Dioxide; Carbon Radioisotopes; Fasting; Glutamine; Lactates; Lactic Acid; Liver; Rats; Rats, Inbred Strains | 1983 |
Changes in blood ammonia, lactate and amino acids in relation to workload during bicycle ergometer exercise in man.
Topics: Adenine Nucleotides; Adult; Alanine; Ammonia; Exercise Test; Glutamine; Humans; Lactates; Lactic Acid; Male; Muscles; Physical Exertion | 1983 |
3-Aminopicolinate inhibits phosphoenolpyruvate carboxykinase in hepatocytes and increases release of gluconeogenic precursors from peripheral tissues.
Topics: Animals; Blood Glucose; Gluconeogenesis; Glutamine; Kidney; Lactates; Lactic Acid; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinates | 1984 |
Factors affecting the induction of phenotypically determined serum resistance of Neisseria gonorrhoeae grown in media containing serum or its diffusible components.
Topics: Blood Bactericidal Activity; Culture Media; Deoxyribonucleases; Dialysis; Glutamine; Humans; Hydrogen-Ion Concentration; Iron; Lactates; Lactic Acid; Neisseria gonorrhoeae; Phenotype; Proline; Temperature | 1981 |
14CO2 fixation by phosphoenolpyruvate carboxykinase during gluconeogenesis in the intact rat liver cell.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Coumaric Acids; Gluconeogenesis; Glutamine; In Vitro Techniques; Lactates; Lactic Acid; Liver; Oxalates; Oxalic Acid; Phosphoenolpyruvate Carboxykinase (GTP); Rats | 1982 |
Ketone body, glucose, lactic acid, and amino acid utilization by tumors in vivo in fasted rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Fasting; Female; Glucose; Glutamine; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred BUF; Rats, Inbred Strains; Sarcoma, Experimental | 1983 |
Comparison of the effects of oviductal cell co-culture and oviductal cell-conditioned medium on the development and metabolic activity of cattle embryos.
Topics: Animals; Blastocyst; Blastomeres; Cattle; Cell Culture Techniques; Culture Media, Conditioned; Embryo, Mammalian; Embryonic and Fetal Development; Fallopian Tubes; Female; Glucose; Glutamine; Lactates; Lactic Acid; Morula; Time Factors | 1995 |
Estimation of glucose-alanine-lactate-glutamine cycles in postabsorptive humans: role of skeletal muscle.
Topics: Adult; Alanine; Blood; Eating; Female; Forearm; Glucose; Glutamine; Humans; Lactates; Lactic Acid; Male; Muscle, Skeletal | 1995 |
Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies.
Topics: Aging; Alanine; Animals; Aspartic Acid; Corpus Striatum; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; In Vitro Techniques; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mitochondria; Rats; Rats, Sprague-Dawley | 1995 |
Glycerol and lactate induce reciprocal changes in glucose formation and glutamine production in isolated rabbit kidney-cortex tubules incubated with aspartate.
Topics: Amino Acids; Ammonia; Animals; Aspartic Acid; Gluconeogenesis; Glucose; Glutamine; Glycerol; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Kinetics; Lactates; Lactic Acid; Methionine Sulfoximine; Models, Biological; Rabbits | 1995 |
Alterations in metabolic properties in fibroblasts in Alzheimer disease.
Topics: Aged; Alzheimer Disease; Blood Glucose; Chromosome Aberrations; Chromosome Disorders; Energy Metabolism; Female; Fibroblasts; Genes, Dominant; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Reference Values | 1995 |
Enhanced production of human monoclonal antibodies by the use of fructose in serum-free hybridoma culture media.
Topics: Antibodies, Monoclonal; Antibodies, Neoplasm; Culture Media, Serum-Free; Fructose; Galactose; Glucose; Glutamine; Humans; Hybridomas; Immunoglobulin G; Lactates; Lactic Acid; Mannose; Perfusion | 1993 |
Calcium alginate immobilized hybridomas grown using a fluidized-bed perfusion system with a protein-free medium.
Topics: Alginates; Antibodies, Monoclonal; Cell Division; Cell Survival; Culture Media; Glucose; Glucuronic Acid; Glutamine; Hexuronic Acids; Hybridomas; Lactates; Lactic Acid; Microspheres; Perfusion | 1994 |
On-line monitoring of an animal cell culture with multi-channel flow injection analysis.
Topics: Animals; Culture Media; Enzymes, Immobilized; Flow Injection Analysis; Glucose; Glutaminase; Glutamine; Hybridomas; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Quaternary Ammonium Compounds | 1994 |
Glutamine-based dipeptides are utilized in mammalian cell culture by extracellular hydrolysis catalyzed by a specific peptidase.
Topics: Amino Acids; Ammonia; Animals; Catalysis; Cell Division; Culture Media, Conditioned; Dipeptides; Glucose; Glutamine; Hybridomas; Hydrolysis; Kinetics; Lactates; Lactic Acid; Mice; Peptide Hydrolases; Sterilization; Substrate Specificity | 1994 |
Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.
Topics: Brain; Carbon Isotopes; Citric Acid Cycle; Glucose; Glutamic Acid; Glutamine; Glycolysis; Humans; Ketoglutaric Acids; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mathematics; Models, Biological; Oxygen Consumption; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid | 1995 |
Intestinal oxygen uptake and glucose metabolism during nutrient absorption in the pig.
Topics: Animals; Female; Glucose; Glutamine; Glycolysis; Insulin; Intestinal Absorption; Intestinal Mucosa; Lactates; Lactic Acid; Oxygen Consumption; Swine | 1994 |
Electrical stimulation and amino acid and ammonia metabolism in the canine gastrocnemius muscle.
Topics: Adenine Nucleotides; Alanine; Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Essential; Ammonia; Animals; Biological Transport, Active; Blood Flow Velocity; Dogs; Electric Stimulation; Female; Glucose; Glutamine; Lactates; Lactic Acid; Male; Muscle Contraction; Muscle, Skeletal; Oxygen Consumption; Sciatic Nerve | 1995 |
Isotopomer studies of gluconeogenesis and the Krebs cycle with 13C-labeled lactate.
Topics: Acetyl Coenzyme A; Alanine; Animals; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Isotope Labeling; Lactates; Lactic Acid; Liver; Male; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Guanosine Diphosphate; Guanosine Triphosphate; Lactates; Lactic Acid; Male; Neurotransmitter Agents; Nitro Compounds; Oxygen Consumption; Phosphocreatine; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 1994 |
The rabbit kidney tubule utilizes glucose for glutamine synthesis. A 13C NMR study.
Topics: Ammonium Chloride; Animals; Carbon Dioxide; Female; Glucose; Glutamine; Glycerol; Glycerophosphates; Glycolysis; Kidney Tubules; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Rabbits | 1994 |
Glucose, galactose, and glutamine metabolism in pig isolated enterocytes during development.
Topics: Animals; Animals, Newborn; Animals, Suckling; Female; Galactose; Glucose; Glutamine; Glycogen; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Kinetics; Lactates; Lactic Acid; Oxidation-Reduction; Pregnancy; Pyruvates; Pyruvic Acid; Swine | 1994 |
Analysis of macromolecule resonances in 1H NMR spectra of human brain.
Topics: Adult; Creatine; Cytosol; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Hydrogen; Image Enhancement; Lactates; Lactic Acid; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Molecular Weight; Peptides; Temporal Lobe | 1994 |
Multichannel flow-injection-analysis biosensor system for on-line monitoring of glucose, lactate, glutamine, glutamate and ammonia in animal cell culture.
Topics: Ammonia; Animals; Biosensing Techniques; Cells, Cultured; Flow Injection Analysis; Glucose; Glutamic Acid; Glutamine; Hybridomas; Lactates; Lactic Acid; Luminescent Measurements; Mice; Online Systems | 1994 |
Cerebral cortex ammonia and glutamine metabolism in two rat models of chronic liver insufficiency-induced hyperammonemia: influence of pair-feeding.
Topics: Amino Acids; Ammonia; Animals; Behavior, Animal; Bile Ducts; Cerebral Cortex; Chronic Disease; Eating; Glucose; Glutamates; Glutamic Acid; Glutamine; Lactates; Lactic Acid; Ligation; Liver Failure; Male; Portacaval Shunt, Surgical; Rats; Rats, Wistar | 1993 |
Glycerol 3-phosphate and lactate as indicators of the cerebral cytoplasmic redox state in severe and mild hypoxia respectively: a 13C- and 31P-n.m.r. study.
Topics: Acetates; Adenosine Triphosphate; Alanine; Cerebral Cortex; Cytoplasm; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerophosphates; Hypoxia, Brain; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Oxidation-Reduction; Phosphocreatine | 1993 |
Metabolism of [U-13C]glutamate in astrocytes studied by 13C NMR spectroscopy: incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycle.
Topics: Animals; Astrocytes; Carbon Isotopes; Cells, Cultured; Citric Acid Cycle; Glutamates; Glutamic Acid; Glutamine; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy | 1993 |
A glutamatergic mechanism for aluminum toxicity in astrocytes.
Topics: Amino Acids; Animals; Astrocytes; Cells, Cultured; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Lactates; Lactic Acid; Rats | 1993 |
Regulation of lactate metabolism by albumin in rat neurons and astrocytes from primary culture.
Topics: 3-Hydroxybutyric Acid; Animals; Astrocytes; Brain; Cells, Cultured; Glucose; Glutamine; Hydroxybutyrates; Lactates; Lactic Acid; Neurons; Rats; Serum Albumin; Serum Albumin, Bovine | 1993 |
Proton magnetic resonance spectroscopy of cerebrospinal fluid as an aid in neurological diagnosis.
Topics: Adult; Aged; Central Nervous System Diseases; Cerebral Infarction; Cerebrospinal Fluid; Female; Glucose; Glutamine; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Meningitis, Bacterial; Middle Aged | 1994 |
Glutamine synthesis from glucose and ammonium chloride by guinea-pig kidney tubules.
Topics: Ammonium Chloride; Animals; Bicarbonates; Carbon Dioxide; Carbon Radioisotopes; Glucose; Glutamine; Guinea Pigs; Kidney Tubules; Lactates; Lactic Acid; Methionine Sulfoximine; Oxidation-Reduction; Pentose Phosphate Pathway; Phosphofructokinase-1; Pyruvate Carboxylase | 1994 |
Propionate regulates lymphocyte proliferation and metabolism.
Topics: Adult; Animals; B-Lymphocytes; Cells, Cultured; DNA; Glucose; Glutamine; Humans; Lactates; Lactic Acid; Lipids; Lymphocyte Activation; Lymphocytes; Male; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; T-Lymphocytes | 1993 |
Metabolic characteristics of pig colonocytes after adaptation to a high fiber diet.
Topics: 3-Hydroxybutyric Acid; Animals; Butyrates; Butyric Acid; Colon; Dietary Fiber; Epithelium; Female; Glucose; Glutamine; Glycolysis; Hexokinase; Hydroxybutyrates; Ketone Bodies; Lactates; Lactic Acid; Oxidation-Reduction; Phosphofructokinase-1; Pyruvate Kinase; Swine | 1993 |
Effects of ethanol on urinary acidification and on gluconeogenesis by isolated renal tubules.
Topics: Amino Acids; Animals; Carbohydrate Metabolism; Cytosol; Diet; Ethanol; Female; Fomepizole; Gluconeogenesis; Glucose; Glutamine; Hydrogen-Ion Concentration; Kidney Tubules; Lactates; Lactic Acid; Male; Mitochondria; NAD; Oleic Acid; Oleic Acids; Oxidation-Reduction; Pyrazoles; Pyruvates; Rats; Rats, Wistar; Serum Albumin; Time Factors; Urine | 1993 |
Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells.
Topics: Animals; Biotransformation; Cell Line, Transformed; CHO Cells; Cricetinae; Enzyme Activation; Glucose; Glutamine; Glycolysis; Kidney; Lactates; Lactic Acid; Liver; Mammals; Mitosis; Spodoptera; Substrate Specificity; Transformation, Genetic | 1996 |
On-line control of an immobilized hybridoma culture with multi-channel flow injection analysis.
Topics: Animals; Antibodies, Monoclonal; Biotechnology; Glucose; Glutamine; Hybridomas; Kinetics; Lactates; Lactic Acid; Models, Biological; Quaternary Ammonium Compounds | 1995 |
Alanine metabolism in isolated human kidney tubules--Use of a mathematical model.
Topics: Adult; Alanine; Dose-Response Relationship, Drug; Drug Interactions; Glutamine; Humans; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Lactates; Lactic Acid; Models, Theoretical | 1996 |
T1 and T2 relaxation times of the major 1H-containing metabolites in rat brain after focal ischemia.
Topics: Animals; Aspartic Acid; Brain; Choline; Creatine; Glutamic Acid; Glutamine; Ischemic Attack, Transient; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phosphocreatine; Rats | 1995 |
The role of glutamine and other alternate substrates as energy sources in the fetal rat lung type II cell.
Topics: 3-Hydroxybutyric Acid; Animals; Carbon Radioisotopes; Embryonic and Fetal Development; Energy Metabolism; Gestational Age; Glucose; Glutamine; Hydroxybutyrates; Lactic Acid; Lung; Oxidation-Reduction; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley | 1996 |
Glucose and glutamine metabolism in C6 glioma cells studied by carbon 13 NMR.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Division; Culture Media; Glioma; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Rats; Tumor Cells, Cultured | 1996 |
Insulin treatment can abolish changes in glucose and glutamine metabolism of lymphocytes and macrophages caused by the implantation of the Walker 256 tumour.
Topics: Animals; Blood Glucose; Carbon Radioisotopes; Carcinoma 256, Walker; Glucose Transporter Type 1; Glutamic Acid; Glutamine; Hypoglycemic Agents; Insulin; Lactic Acid; Lymphocyte Activation; Lymphocytes; Macrophages; Male; Monosaccharide Transport Proteins; Neoplasm Transplantation; Rats; Rats, Wistar | 1996 |
The effect of N-3 PUFA rich diet upon macrophage and lymphocyte metabolism and function.
Topics: Animals; Dietary Fats; Fatty Acids, Unsaturated; Glucose; Glutamine; Hydrogen Peroxide; Lactic Acid; Lymphocytes; Macrophages; Male; Phagocytosis; Rats; Rats, Wistar | 1996 |
Noninvasive probing of citric acid cycle intermediates in primate liver with phenylacetylglutamine.
Topics: Animals; Carbon Isotopes; Citric Acid Cycle; Female; Glutamic Acid; Glutamine; Ketoglutaric Acids; Kidney; Lactic Acid; Liver; Macaca mulatta; Muscles; Phenylacetates | 1996 |
Differential regulation of mouse embryo development and viability by amino acids.
Topics: Amino Acids; Animals; Blastocyst; Cell Division; Cells, Cultured; Culture Media; Embryo Transfer; Fetal Viability; Glucose; Glutamine; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred CBA | 1997 |
Effect of ischaemia and reperfusion on the intracellular concentration of taurine and glutamine in the hearts of patients undergoing coronary artery surgery.
Topics: Adenosine Triphosphate; Aged; Bicarbonates; Biomarkers; Blood; Calcium Chloride; Cardioplegic Solutions; Coronary Artery Bypass; Female; Glutamine; Humans; Lactic Acid; Magnesium; Male; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Potassium Chloride; Sodium Chloride; Taurine; Troponin; Troponin I; Troponin T | 1997 |
Gonadotropins, serum, and amino acids alter nuclear maturation, cumulus expansion, and oocyte morphology in hamster cumulus-oocyte complexes in vitro.
Topics: Actin Cytoskeleton; Amino Acids; Animals; Blood Proteins; Cattle; Cell Nucleus; Cricetinae; Culture Media; Female; Follicle Stimulating Hormone; Glucose; Glutamine; In Vitro Techniques; Lactic Acid; Luteinizing Hormone; Mesocricetus; Oocytes; Pyruvic Acid | 1997 |
Which amino-acids do serum and hemofiltrate of critically ill patients with acute renal failure contain?
Topics: Alanine; Amino Acids; Asparagine; Citrulline; Cystathionine; Ethanolamines; Extracorporeal Circulation; Glutamine; Glycine; Hemofiltration; Histidine; Humans; Kidney Failure, Chronic; Lactic Acid; Methionine; Proline | 1997 |
Metabolic stroke in carbamyl phosphate synthetase deficiency.
Topics: Ammonia; Brain Damage, Chronic; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cerebrovascular Disorders; Female; Follow-Up Studies; Glutamine; Hemiplegia; Humans; Infant; Lactic Acid; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 1997 |
Ketone bodies activate gluconeogenesis in isolated rabbit renal cortical tubules incubated in the presence of amino acids and glycerol.
Topics: Amino Acids; Animals; Carbon Dioxide; Gluconeogenesis; Glucose; Glutamic Acid; Glutamine; Glycerol; In Vitro Techniques; Ketone Bodies; Kidney Cortex; Kidney Tubules; Lactic Acid; Male; Rabbits | 1997 |
Trafficking of amino acids between neurons and glia in vivo. Effects of inhibition of glial metabolism by fluoroacetate.
Topics: Acetates; Amino Acids; Animals; Behavior, Animal; Blood; Brain; Citric Acid; Female; Fluoroacetates; Glucose; Glutamine; Lactic Acid; Mice; Mice, Inbred Strains; Neuroglia; Neurons | 1997 |
Brain lactate by magnetic resonance spectroscopy during fulminant hepatic failure in the dog.
Topics: Animals; Biomarkers; Brain; Dogs; Dose-Response Relationship, Drug; Feasibility Studies; Galactosamine; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Intracranial Hypertension; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Time Factors | 1998 |
An oral glutamine load enhances renal acid secretion and function.
Topics: Adolescent; Adult; Bicarbonates; Glomerular Filtration Rate; Glutamine; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kidney; Kinetics; Lactic Acid; Male; Middle Aged; Quaternary Ammonium Compounds | 1998 |
The effects of high-intensity intermittent exercise on the plasma concentrations of glutamine and organic acids.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; Ammonia; Exercise; Exercise Test; Fatty Acids, Nonesterified; Glutamine; Heart Rate; Humans; Hydroxybutyrates; Kidney; Lactic Acid; Leukocyte Count; Male; Oxygen Consumption | 1998 |
Energy metabolism of rat colonocytes changes during the tumorigenic process and is dependent on diet and carcinogen.
Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Butyrates; Butyric Acid; Carcinogens; Cellulose; Colon; Colonic Neoplasms; Diet; Energy Metabolism; Glucose; Glutamine; Hydroxybutyrates; Ketone Bodies; Kinetics; Lactic Acid; Male; Oxidation-Reduction; Pectins; Rats; Rats, Sprague-Dawley | 1998 |
Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from Alzheimer patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrospinal Fluid; Citric Acid Cycle; Female; Fumarates; Glutamine; Humans; Lactic Acid; Male; Mitochondria; Reference Values; Substrate Specificity; Succinic Acid | 1998 |
Localized in vivo 13C-NMR of glutamate metabolism in the human brain: initial results at 4 tesla.
Topics: Aspartic Acid; Blood Glucose; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Magnetics; Models, Biological; Visual Cortex | 1998 |
Heteronuclear cross polarization for enhanced sensitivity of in vivo 13C MR spectroscopy on a clinical 1.5 T MR system.
Topics: Adipose Tissue; Animals; Brain Chemistry; Feasibility Studies; Glucose; Glutamine; Humans; Image Enhancement; Lactic Acid; Magnetic Resonance Spectroscopy; Phantoms, Imaging; Sensitivity and Specificity; Swine; Triglycerides | 1998 |
Importance of glutamate dehydrogenase stimulation for glucose and glutamine synthesis in rabbit renal tubules incubated with various amino acids.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Enzyme Activation; Glucose; Glutamate Dehydrogenase; Glutamine; Kidney Tubules; Lactic Acid; Male; Rabbits | 1998 |
Energy substrates and amino acids provided during in vitro maturation of bovine oocytes alter acquisition of developmental competence.
Topics: Amino Acids; Animals; Blastocyst; Cattle; Cleavage Stage, Ovum; Culture Media, Serum-Free; Energy Metabolism; Female; Fertilization in Vitro; Glucose; Glutamine; In Vitro Techniques; Lactic Acid; Oocytes | 1998 |
Lactate inhibits citrulline and arginine synthesis from proline in pig enterocytes.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling; Arginine; Citrulline; Enzyme Inhibitors; Glutamine; Jejunum; Kinetics; Lactic Acid; Mitochondria; Proline; Proline Oxidase; Swine | 1999 |
Delayed labelling of brain glutamate after an intra-arterial [13C]glucose bolus: evidence for aerobic metabolism of guinea pig brain glycogen store.
Topics: Aerobiosis; Animals; Brain; Carbon Isotopes; Cerebellum; Cerebral Cortex; Glucose; Glutamic Acid; Glutamine; Glycogen; Guinea Pigs; Infusions, Intra-Arterial; Lactic Acid; Magnetic Resonance Spectroscopy; Time Factors | 1999 |
Noninvasive tracing of human liver metabolism: comparison of phenylacetate and apoB-100 to sample glutamine.
Topics: Adult; Apolipoprotein B-100; Apolipoproteins B; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glutamine; Hormones; Humans; Lactic Acid; Liver; Male; Middle Aged; Phenylacetates; Reference Values | 1999 |
Metabolic shifts by nutrient manipulation in continuous cultures of BHK cells.
Topics: Amino Acids; Ammonia; Animals; Bioreactors; Cell Count; Cell Culture Techniques; Cell Line; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Glucose; Glutamine; Kidney; Lactic Acid; Models, Biological | 1999 |
Acute effects of leptin on glucose metabolism of in situ rat perfused livers and isolated hepatocytes.
Topics: Alanine; Animals; Glucagon; Gluconeogenesis; Glucose; Glutamine; Glycerol; Glycogen; Lactic Acid; Leptin; Liver; Male; Rats; Rats, Wistar | 1999 |
Gluconeogenesis in the liver of arthritic rats.
Topics: Alanine; Animals; Arthritis, Experimental; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Oxygen; Pyruvic Acid; Rats; Rats, Wistar; Xylitol | 1999 |
Differences in fuel utilization between trout and human thrombocytes in physiological media.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Cell Survival; Culture Media; Energy Metabolism; Glucose; Glutamine; Humans; Lactic Acid; Oncorhynchus mykiss; Oxygen; Oxygen Consumption; Palmitic Acid; Species Specificity | 1999 |
Mechanisms of glutamate metabolic signaling in retinal glial (Müller) cells.
Topics: Ambystoma; Animals; Biosensing Techniques; Citric Acid Cycle; Flavin-Adenine Dinucleotide; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Microscopy, Fluorescence; NADP; Neuroglia; Neurons, Afferent; Quaternary Ammonium Compounds; Retina; Signal Transduction | 2000 |
Effect of dexamethasone on fetal hepatic glutamine-glutamate exchange.
Topics: Alanine; Animals; Blood Glucose; Carbon Isotopes; Dexamethasone; Female; Fetal Weight; Gestational Age; Glucocorticoids; Glucose; Glutamic Acid; Glutamine; Infusions, Intravenous; Lactic Acid; Liver; Liver Circulation; Organ Size; Sheep; Umbilical Veins | 2000 |
Hyperammonemia induced by administration of glucose and insulin after hepatopancreatectomy in rats.
Topics: Alanine; Ammonia; Animals; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hepatectomy; Insulin; Lactic Acid; Male; Pancreatectomy; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Anxiety in healthy humans is associated with orbital frontal chemistry.
Topics: Adult; Analysis of Variance; Anxiety; Aspartic Acid; Choline; Creatinine; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neurotransmitter Agents; Psychological Tests | 2000 |
NMR spectroscopic study on the metabolic fate of [3-(13)C]alanine in astrocytes, neurons, and cocultures: implications for glia-neuron interactions in neurotransmitter metabolism.
Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Aspartic Acid; Astrocytes; Carbon Isotopes; Cell Communication; Cells, Cultured; Citric Acid Cycle; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Neurons; Neurotransmitter Agents; Protein Transport; Rats; Rats, Wistar | 2000 |
Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Anxiety; Aspartic Acid; Back Pain; Brain Chemistry; Choline; Chronic Disease; Creatine; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Prefrontal Cortex; Thalamus | 2000 |
Human 293 cell metabolism in low glutamine-supplied culture: interpretation of metabolic changes through metabolic flux analysis.
Topics: Amino Acids; Ammonia; Bioreactors; Cell Count; Cell Culture Techniques; Cell Division; Cell Line; Citric Acid Cycle; Culture Media; Glucose; Glutamine; Humans; Kidney; Kinetics; Lactic Acid; Models, Biological | 2000 |
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport; Brain Ischemia; Cerebral Cortex; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Energy Metabolism; Ethanolamines; gamma-Aminobutyric Acid; Glucose; Glutamine; Lactic Acid; Male; Pyruvic Acid; Quercetin; Rats; Rats, Sprague-Dawley | 2001 |
Net amino acid flux across the fetal liver and placenta during spontaneous ovine parturition.
Topics: Amino Acids; Animals; Biological Transport; Dexamethasone; Female; Fetal Blood; Glucocorticoids; Glucose; Glutamic Acid; Glutamine; Hydrocortisone; Labor, Induced; Labor, Obstetric; Lactic Acid; Liver; Placenta; Pregnancy; Sheep | 2001 |
13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Compartmentation; Cell Extracts; Cells, Cultured; Culture Media; Cytosol; Energy Metabolism; Enzymes; Glucose; Glutamic Acid; Glutamine; Hydrogen; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2001 |
Rates of gluconeogenesis in perfused liver of alloxan-diabetic fed rats.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fructose; Gluconeogenesis; Glucose; Glutamine; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Uric Acid | 2000 |
The effect of thiopental on glutamate metabolism in mouse cerebellar astrocytes in vitro.
Topics: Animals; Astrocytes; Carbon Isotopes; Cell Extracts; Cells, Cultured; Cerebellum; Citric Acid Cycle; Culture Media; Drug Combinations; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Thiopental | 2001 |
Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Cryoprotective Agents; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2001 |
High glycolytic activity in rat glioma demonstrated in vivo by correlation peak 1H magnetic resonance imaging.
Topics: Alanine; Animals; Aspartic Acid; Brain Neoplasms; Choline; Creatine; Ethanolamines; Female; Glioma; Glucose; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Imaging; Phosphocreatine; Rats; Rats, Sprague-Dawley; Taurine; Tumor Cells, Cultured | 2001 |
Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes.
Topics: Amino Acids; Animals; Astrocytes; Carbon Radioisotopes; Cell Compartmentation; Cells, Cultured; Cerebellum; Citric Acid; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Intracellular Fluid; Lactic Acid; Mice; Pyruvic Acid | 2001 |
Cultivation of hamster kidney cells in a dynamic cell culture system in space (Spacelab IML-1 Mission).
Topics: Ammonia; Animals; Cell Culture Techniques; Cell Division; Cells, Cultured; Cricetinae; Culture Media; Dextrans; Evaluation Studies as Topic; Glucose; Glutamine; Hydrogen-Ion Concentration; Kidney; Lactic Acid; Space Flight; Tissue Plasminogen Activator; Weightlessness | 1993 |
Effect of exogenous lactate on rat glioma metabolism.
Topics: Animals; Blood Glucose; Brain; Brain Neoplasms; Carbon; Carbon Radioisotopes; Citric Acid Cycle; Energy Metabolism; Female; Glioma; Glucose; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; NAD; Neurons; Rats; Rats, Wistar; Tumor Cells, Cultured | 2001 |
Vero cells, but not oviductal cells, increase the hatching frequency and total cell count of mouse blastocysts partly by changing energy substrate concentrations in culture medium.
Topics: Animals; Blastocyst; Chlorocebus aethiops; Coculture Techniques; Culture Media, Conditioned; Embryonic and Fetal Development; Fallopian Tubes; Female; Glutamine; Humans; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Pyruvic Acid; Vero Cells | 2001 |
Gluconeogenesis from glutamine and lactate in the isolated human renal proximal tubule: longitudinal heterogeneity and lack of response to adrenaline.
Topics: Animals; Cyclic AMP; Epinephrine; Female; Gluconeogenesis; Glutamine; Humans; In Vitro Techniques; Kidney Tubules, Proximal; Lactic Acid; Male; Middle Aged; Norepinephrine; Rats | 2001 |
Estimation of aspartate synthesis in GABAergic neurons in mice by 13 C NMR spectroscopy.
Topics: 3-Mercaptopropionic Acid; Acetates; Amino Acids; Animals; Aspartic Acid; Carbon Radioisotopes; Cerebral Cortex; Energy Metabolism; GABA Agents; gamma-Aminobutyric Acid; Glucose; Glutamate Decarboxylase; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Mice; Nerve Tissue Proteins; Neurons; Synaptic Transmission | 2001 |
Erythropoietin production from CHO cells grown by continuous culture in a fluidized-bed bioreactor.
Topics: Amino Acids; Ammonia; Animals; Bioreactors; Cell Division; CHO Cells; Chromatography, Affinity; Cricetinae; Culture Media; Electrophoresis, Capillary; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Glucose; Glutamine; Glycosylation; Lactic Acid | 2002 |
Renal substrate exchange and gluconeogenesis in normal postabsorptive humans.
Topics: Adult; Alanine; Female; Gluconeogenesis; Glucose; Glutamine; Glycerol; Humans; Kidney; Lactic Acid; Male; Middle Aged; Postprandial Period; Reference Values | 2002 |
Fetal hepatic and umbilical uptakes of glucogenic substrates during a glucagon-somatostatin infusion.
Topics: Alanine; Animals; Arginine; Blood Glucose; Female; Fetal Blood; Gestational Age; Glucagon; Gluconeogenesis; Glucose; Glutamine; Lactic Acid; Liver; Ornithine; Oxygen Consumption; Placenta; Pregnancy; Pyruvic Acid; Sheep; Somatostatin; Umbilical Veins | 2002 |
Preventive effect of glutamine on intestinal barrier dysfunction induced by severe trauma.
Topics: Amine Oxidase (Copper-Containing); Animals; Endotoxemia; Endotoxins; Glutamine; Intestinal Absorption; Lactic Acid; Male; Rats; Rats, Wistar; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha; Wounds and Injuries | 2002 |
Biosensor arrays for simultaneous measurement of glucose, lactate, glutamate, and glutamine.
Topics: Biosensing Techniques; Enzymes, Immobilized; Equipment Design; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Membranes, Artificial; Microelectrodes; Polyhydroxyethyl Methacrylate | 2002 |
Induction of protein aggregation in an early secretory compartment by elevation of expression level.
Topics: Animals; Antithrombin III; Blotting, Western; Cell Division; Cells, Cultured; CHO Cells; Cricetinae; Disulfides; Endoplasmic Reticulum; Enzyme-Linked Immunosorbent Assay; Glucose; Glutamine; Golgi Apparatus; Hexosaminidases; Humans; Lactic Acid; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Molecular Weight; Protein Conformation; Quaternary Ammonium Compounds; Recombinant Proteins | 2002 |
[Effects of glucose on growth, metabolism and EPO expression in recombinant CHO cell cultures].
Topics: Animals; Cell Division; Cells, Cultured; CHO Cells; Cricetinae; Erythropoietin; Glucose; Glutamine; Lactic Acid; Recombinant Proteins; Transgenes | 2001 |
Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1'S,2'R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy.
Topics: Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Animals; Carbon Isotopes; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Guinea Pigs; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Oocytes; Pyruvate Carboxylase; Pyruvic Acid; Xenopus laevis | 2002 |
Identification of lactate as a driving force for prostanoid transport by prostaglandin transporter PGT.
Topics: Antiporters; Biological Transport; Deoxyglucose; Dinoprostone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression; Glucose; Glutamine; Glycolysis; HeLa Cells; Humans; Lactic Acid; Organic Anion Transporters; Oxidative Phosphorylation; Prostaglandins; Transfection | 2002 |
Amino acid kinetics during the anhepatic phase of liver transplantation.
Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid | 2002 |
Alteration of amino acid metabolism in neuronal aggregate cultures exposed to hypoglycaemic conditions.
Topics: Amino Acids; Animals; Cell Aggregation; Cells, Cultured; Dose-Response Relationship, Drug; Energy Metabolism; Extracellular Space; Glucose; Glutamine; Intracellular Fluid; Lactic Acid; Neurons; Oxidation-Reduction; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Telencephalon | 2002 |
Hepatic gluconeogenic capacity from various precursors in young versus old rats.
Topics: Aging; Alanine; Animals; Body Weight; Cell Separation; Cell Survival; Dihydroxyacetone; Fasting; Fructose; Gluconeogenesis; Glucose; Glutamine; Glycerol; Glycogen; Hepatocytes; Lactic Acid; Liver; Male; Oxaloacetates; Pyruvic Acid; Rats; Rats, Inbred F344 | 2002 |
Serum-free suspension cultivation of PER.C6(R) cells and recombinant adenovirus production under different pH conditions.
Topics: Adenoviridae; Bioreactors; Cell Line; Culture Media, Serum-Free; Glucose; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Quality Control; Quaternary Ammonium Compounds; Recombination, Genetic; Reference Values; Reproducibility of Results; Retina; Sensitivity and Specificity; Stem Cells; Virus Cultivation | 2002 |
Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus.
Topics: Acetates; Animals; Astrocytes; Biomarkers; Brain Stem; Carbon Isotopes; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Hydrocephalus; Kaolin; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Neurotransmitter Agents; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Taurine; Telencephalon | 2003 |
Effect of aspartate and asparagine supplementation on fatigue determinants in intense exercise.
Topics: Alanine; Animals; Asparagine; Aspartic Acid; Blood Glucose; Dietary Supplements; Glutamine; Glycogen; Lactic Acid; Liver Glycogen; Male; Muscle Fatigue; Muscle, Skeletal; Physical Conditioning, Animal; Physical Exertion; Random Allocation; Rats; Rats, Wistar; Swimming | 2003 |
Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.
Topics: Acetic Acid; Alanine; Animals; Astrocytes; beta-Alanine; Biological Transport; Carbon Isotopes; Cell Compartmentation; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Humans; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Neuroblastoma; Rats | 2003 |
The contribution of glycolytic and oxidative pathways to retinal photoreceptor function.
Topics: Aerobiosis; Anaerobiosis; Animals; Dark Adaptation; Drug Combinations; Electroretinography; Glucose; Glutamine; Glycolysis; Hypoglycemia; Hypoxia; Lactic Acid; Oxidative Stress; Oxygen; Photoreceptor Cells, Vertebrate; Rats; Rats, Long-Evans; Vision, Ocular; Vitreous Body | 2003 |
Luminal fermentation and colonocyte metabolism in a rat model of enteral nutrition.
Topics: Ammonia; Animals; Bacteria; Butyrates; Enteral Nutrition; Enterocytes; Fatty Acids, Volatile; Fermentation; Gastrointestinal Contents; Glutamine; Intestine, Large; Lactic Acid; Male; Models, Animal; Rats; Rats, Wistar | 2003 |
Design of luminescent biochips based on enzyme, antibody, or DNA composite layers.
Topics: Antibodies; Biosensing Techniques; Choline; DNA; Enzymes; Glucose; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Luminescent Measurements; Lysine; Uric Acid | 2003 |
In-situ near infrared spectroscopy to monitor key analytes in mammalian cell cultivation.
Topics: Ammonia; Animals; Bioreactors; Calibration; Cell Culture Techniques; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Glucose; Glutamine; Lactic Acid; Metabolism; Models, Biological; Spectroscopy, Near-Infrared | 2003 |
Virus-like particle production at low multiplicities of infection with the baculovirus insect cell system.
Topics: Algorithms; Animals; Baculoviridae; Capsid Proteins; Cell Culture Techniques; Cell Division; Cell Survival; Dose-Response Relationship, Radiation; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Parvovirus, Porcine; Recombinant Proteins; Spodoptera; Viral Plaque Assay; Virion; Virus Cultivation; Virus Replication | 2003 |
Defining a metabolic phenotype in the brain of a transgenic mouse model of spinocerebellar ataxia 3.
Topics: Animals; Ataxin-3; Brain; Cerebellum; Choline; Disease Models, Animal; gamma-Aminobutyric Acid; Glucose; Glutamine; Glycogen; Humans; Lactic Acid; Machado-Joseph Disease; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Phenotype; Phosphorylcholine; Repressor Proteins; Telencephalon; Transcription Factors; Trinucleotide Repeat Expansion | 2004 |
Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Blotting, Western; Cardiomegaly; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Glutamate Dehydrogenase; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Heart; Heart Rate; Ischemia; Kinetics; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardium; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reperfusion; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Sarcolemma; Symporters; Ventricular Pressure | 2004 |
Impact of temperature reduction and expression of yeast pyruvate carboxylase on hGM-CSF-producing CHO cells.
Topics: Animals; Cell Nucleus; Cell Survival; CHO Cells; Cold Temperature; Cricetinae; Cricetulus; Glucose; Glutamine; Humans; Lactic Acid; Macrophage Colony-Stimulating Factor; Pyruvate Carboxylase; Recombinant Proteins; Temperature; Yeasts | 2004 |
Strategies for fed-batch cultivation of t-PA producing CHO cells: substitution of glucose and glutamine and rational design of culture medium.
Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Culture Media; Galactose; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Time Factors; Tissue Plasminogen Activator | 2004 |
Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture.
Topics: Amino Acids; Animals; Apoptosis; Aspartic Acid; Cell Line; Cell Proliferation; Cells, Immobilized; Dogs; Glucose; Glutamine; Hemagglutinin Glycoproteins, Influenza Virus; Influenza A virus; Kinetics; Lactic Acid; Methionine; Proline; Quaternary Ammonium Compounds; Serine; Virus Cultivation; Virus Replication | 2004 |
On-line monitoring of human prostate cancer cells in a perfusion rotating wall vessel by near-infrared spectroscopy.
Topics: Ammonia; Bioreactors; Cell Culture Techniques; Cell Line, Tumor; Glucose; Glutamine; Humans; Lactic Acid; Male; Perfusion; Prostatic Neoplasms; Spectroscopy, Near-Infrared | 2004 |
Glutamine supplemented parenteral nutrition prevents intestinal ischemia- reperfusion injury in rats.
Topics: Animals; Atrophy; Bacterial Translocation; Glutamine; Intestinal Mucosa; Intestines; Lactic Acid; Male; Parenteral Nutrition; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survival Rate | 2004 |
In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death.
Topics: Animals; Apoptosis; Brain; Brain Injuries; Cell Death; Cell Survival; Denervation; Disease Models, Animal; Energy Metabolism; Fornix, Brain; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hippocampus; L-Lactate Dehydrogenase; Lactic Acid; Male; Necrosis; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley | 2004 |
Human sebaceous glands engage in aerobic glycolysis and glutaminolysis.
Topics: Aerobiosis; Amino Acids; Ammonia; Carbon; Female; Glucose; Glutamine; Glycolysis; Humans; Lactic Acid; Male; Nitrogen; Oxidation-Reduction; Pentose Phosphate Pathway; Sebaceous Glands; Spermidine | 2004 |
Characteristics of glutamine metabolism in human precision-cut kidney slices: a 13C-NMR study.
Topics: Ammonia; Carbon Isotopes; Dose-Response Relationship, Drug; Glucose; Glutamine; Humans; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Valproic Acid | 2005 |
A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother.
Topics: Adipose Tissue; Antiretroviral Therapy, Highly Active; Arginine; Asphyxia; Brain; Cardiomegaly; Cardiomyopathy, Hypertrophic; Cholestasis; Fatal Outcome; Female; Fetal Macrosomia; Glutamine; Hepatomegaly; HIV Infections; Humans; Hypoglycemia; Infant, Newborn; Infectious Disease Transmission, Vertical; Lactic Acid; Liver Function Tests; Myocardium; Necrosis; Pregnancy; Pregnancy Complications, Infectious; Skin Diseases | 2005 |
Extracellular metabolites in the cortex and hippocampus of epileptic patients.
Topics: Adolescent; Adult; Cerebral Cortex; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy, Temporal Lobe; Extracellular Fluid; Female; Glucose; Glutamic Acid; Glutamine; Hippocampus; Humans; Lactic Acid; Male; Microdialysis; Middle Aged | 2005 |
High-field localized 1H NMR spectroscopy in the anesthetized and in the awake monkey.
Topics: Anesthesia, General; Animals; Artifacts; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dipeptides; Glutamic Acid; Glutamine; Glutathione; Hydrogen; Image Enhancement; Inositol; Lactic Acid; Macaca mulatta; Magnetic Resonance Spectroscopy; Phosphocreatine; Stereoisomerism; Taurine; Wakefulness | 2004 |
Ammonia effects on pyruvate/lactate production in astrocytes--interaction with glutamate.
Topics: Ammonia; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Glutamic Acid; Glutamine; Glutathione; Glycolysis; Hyperammonemia; Interneurons; Lactic Acid; Malates; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Pyruvic Acid; Up-Regulation | 2005 |
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Brain; Brain Diseases, Metabolic; Brain Edema; Carbon Radioisotopes; Choline; Disease Models, Animal; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Lupus Erythematosus, Systemic; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Protons; Up-Regulation | 2005 |
Stable hybridoma cultivation in a pilot-scale acoustic perfusion system: long-term process performance and effect of recirculation rate.
Topics: Antibodies, Monoclonal; Bioreactors; Cell Count; Cell Culture Techniques; Cell Survival; Efficiency; Fermentation; Glucose; Glutamine; Hybridomas; Lactic Acid; Oxygen; Perfusion | 2005 |
A novel control scheme for inducing angiostatin-human IgG fusion protein production using recombinant CHO cells in a oscillating bioreactor.
Topics: Ammonia; Angiostatins; Animals; Bioreactors; Biotechnology; Cell Count; Cell Culture Techniques; CHO Cells; Cricetinae; Culture Media; Enzyme-Linked Immunosorbent Assay; Glucose; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Kinetics; Lactic Acid; Recombinant Fusion Proteins | 2006 |
Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury.
Topics: Animals; Brain Injuries; Citric Acid Cycle; Disease Models, Animal; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Pentose Phosphate Pathway; Rats; Up-Regulation | 2005 |
Metabolic profiling by 13C-NMR spectroscopy: [1,2-13C2]glucose reveals a heterogeneous metabolism in human leukemia T cells.
Topics: Carbon Isotopes; Cell Cycle; Cell Proliferation; Citric Acid Cycle; Glucose; Glutamine; Glycine; Humans; Jurkat Cells; Lactic Acid; Leukemia, T-Cell; Magnetic Resonance Spectroscopy; Models, Biological; Nucleotides; Pentose Phosphate Pathway; Pentoses; Serine | 2006 |
Effects of culture media and energy sources on the inhibition of nuclear maturation in bovine oocytes.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Culture Media; Dose-Response Relationship, Drug; Female; Glucose; Glutamine; Hypoxanthine; Lactic Acid; Meiosis; Oocytes; Pyruvic Acid; Species Specificity | 2006 |
Intrinsic gluconeogenesis is enhanced in renal proximal tubules of Zucker diabetic fatty rats.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructose-Bisphosphatase; Gluconeogenesis; Glucose-6-Phosphatase; Glutamine; Glycerol; Kidney Tubules, Proximal; Lactic Acid; Male; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Zucker; RNA, Messenger; Tissue Culture Techniques | 2006 |
Serum-free influenza virus production avoiding washing steps and medium exchange in large-scale microcarrier culture.
Topics: Ammonia; Animals; Bioreactors; Cell Count; Cell Culture Techniques; Cell Line; Cells, Immobilized; Culture Media; Culture Media, Serum-Free; Dogs; Glucose; Glutamic Acid; Glutamine; Hemagglutinin Glycoproteins, Influenza Virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N8 Subtype; Lactic Acid; Microspheres; Oxygen; Virus Cultivation | 2006 |
Metabolism of PER.C6 cells cultivated under fed-batch conditions at low glucose and glutamine levels.
Topics: Adenoviridae; Amino Acids; Ammonia; Bioreactors; Cell Count; Cell Culture Techniques; Cell Line, Transformed; Cell Survival; Cell Transformation, Viral; Culture Media; Culture Media, Serum-Free; Energy Metabolism; Glucose; Glutamine; Humans; Lactic Acid; Oxygen; Retina; Time Factors | 2006 |
Retrovirus producer cell line metabolism: implications on viral productivity.
Topics: Adenosine Triphosphate; Alanine; Cell Count; Cell Line, Tumor; Culture Media; Fatty Acids; Fructose; Genetic Vectors; Glucose; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Phosphocreatine; Retroviridae; Virus Cultivation | 2006 |
Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Female; Galactose; Glucose; Glutamine; Glyceraldehyde; Islets of Langerhans; Keto Acids; Lactic Acid; Leucine; Mannose; Nutritional Physiological Phenomena; Pyruvic Acid; Rats; Rats, Wistar | 2006 |
Effect of postruminal glutamine supplementation on immune response and milk production in dairy cows.
Topics: 3-Hydroxybutyric Acid; Abomasum; Amino Acids; Animals; Blood Glucose; Cattle; CD4-CD8 Ratio; Concanavalin A; Diet; Dietary Supplements; Eating; Fatty Acids, Nonesterified; Female; Glutamine; Immunity; Interferon-gamma; Lactation; Lactic Acid; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Milk; Nitrogen; Pregnancy; T-Lymphocytes | 2006 |
Estradiol stimulates the biosynthetic pathways of breast cancer cells: detection by metabolic flux analysis.
Topics: Algorithms; Amino Acids; Biosynthetic Pathways; Breast Neoplasms; Carbon Isotopes; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Estradiol; Female; Glucose; Glutamic Acid; Glutamine; Humans; Lactic Acid; Mitochondria; Models, Biological; Nuclear Magnetic Resonance, Biomolecular | 2006 |
Towards industrial application of quasi real-time metabolic flux analysis for mammalian cell culture.
Topics: Animals; Bioreactors; Biotechnology; Cell Culture Techniques; CHO Cells; Citrate (si)-Synthase; Citric Acid Cycle; Cricetinae; Cricetulus; Glucose; Glutamine; Ketone Oxidoreductases; Lactic Acid; Models, Biological; Pyruvate Kinase; Pyruvic Acid; Signal Transduction | 2006 |
Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients.
Topics: Astrocytes; Brain; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Male; Microdialysis; Neurons; Pyruvic Acid; Subarachnoid Hemorrhage | 2007 |
Metabolic and immune responses in Chinese mitten-handed crab (Eriocheir sinensis) juveniles exposed to elevated ambient ammonia.
Topics: Ammonia; Animals; Brachyura; Glutamine; Hemolymph; Lactic Acid; Lethal Dose 50; Superoxide Dismutase | 2007 |
Brain energy metabolism and neurotransmission at near-freezing temperatures: in vivo (1)H MRS study of a hibernating mammal.
Topics: Animals; Ascorbic Acid; Aspartic Acid; Brain; Brain Chemistry; Choline; Cold Temperature; Creatine; Energy Metabolism; Ethanolamines; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Glutathione; Hibernation; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphocreatine; Sciuridae; Synaptic Transmission; Taurine | 2007 |
The fate of glucose during the period of decreased metabolism after fluid percussion injury: a 13C NMR study.
Topics: Animals; Brain Injuries; Carbon Isotopes; Cerebral Cortex; Down-Regulation; Free Radicals; Glucose; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Male; NADP; Oxidative Phosphorylation; Oxidative Stress; Pentose Phosphate Pathway; Rats; Rats, Sprague-Dawley; Time Factors; Wounds, Nonpenetrating | 2007 |
Association of reduced extracellular brain ammonia, lactate, and intracranial pressure in pigs with acute liver failure.
Topics: Ammonia; Animals; Brain Chemistry; Disease Models, Animal; Extracellular Space; Female; Glutamic Acid; Glutamine; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Sorption Detoxification; Swine | 2007 |
Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic beta-cell line.
Topics: Adenosine Triphosphate; Alanine; Analysis of Variance; Animals; Cell Line; Cytochalasin D; Cytokines; Glucose; Glutamic Acid; Glutamine; Insulin; Insulin Secretion; Insulin-Secreting Cells; Interferon-gamma; Interleukin-1beta; L-Lactate Dehydrogenase; Lactic Acid; Triglycerides; Tumor Necrosis Factor-alpha | 2007 |
Na+-dependent neutral amino acid transporter ASCT2 is downregulated in seriously traumatized human intestinal epithelial cells.
Topics: Alanine; Amino Acid Transport System ASC; Amino Acids; Blotting, Western; Caco-2 Cells; Cell Hypoxia; Culture Media; Down-Regulation; Glutamine; Humans; Intestinal Mucosa; Ischemia; Kinetics; Lactic Acid; Minor Histocompatibility Antigens; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sepsis; Tritium | 2008 |
Cerebral glutamine concentration and lactate-pyruvate ratio in patients with acute liver failure.
Topics: Adolescent; Adult; Aged; Astrocytes; Brain; Brain Edema; Critical Care; Female; Glutamine; Humans; Hyperammonemia; Intracranial Hypertension; Lactic Acid; Liver Failure, Acute; Male; Microdialysis; Middle Aged; Mitochondria; Pyruvic Acid; Severity of Illness Index | 2008 |
[Metabonomic study of blood plasma in the assessment of liver graft function].
Topics: Acetone; Alanine; Biomarkers; Blood Glucose; Carcinoma; Choline; Glutamine; Humans; Lactic Acid; Liver; Liver Neoplasms; Liver Transplantation; Magnetic Resonance Spectroscopy; Male; Metabolome; Succinic Acid; Treatment Outcome; Valine | 2007 |
No effect of glutamine supplementation and hyperoxia on oxidative metabolism and performance during high-intensity exercise.
Topics: Adult; Bicycling; Blood Glucose; Cell Respiration; Dietary Supplements; Energy Metabolism; Exercise; Exercise Test; Glutamine; Humans; Hyperoxia; Lactic Acid; Oxygen Consumption; Physical Endurance; Pulmonary Gas Exchange | 2008 |
1H/13C MR spectroscopic imaging of regionally specific metabolic alterations after experimental stroke.
Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Models, Animal; Neuroglia; Neurons; Neuropsychological Tests; Rats; Rats, Wistar; Stroke | 2008 |
Acute tolerance and metabolic responses of Chinese mitten crab (Eriocheir sinensis) juveniles to ambient nitrite.
Topics: Animals; Brachyura; Cell Hypoxia; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Glutamine; Hemocyanins; Hemolymph; Hepatopancreas; Lactic Acid; Lethal Dose 50; Oxygen; Sodium Nitrite; Time Factors; Urea | 2009 |
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Time Factors; Weaning | 2009 |
Growth, metabolism, and growth inhibitors of mesenchymal stem cells.
Topics: Adult; Ammonia; Animals; Cell Proliferation; Cell Shape; Glucose; Glutamine; Goats; Growth Inhibitors; Humans; Lactic Acid; Mesenchymal Stem Cells; Multipotent Stem Cells; Organ Specificity; Rats; Time Factors; Tissue Donors | 2009 |
Quantifying in vitro growth and metabolism kinetics of human mesenchymal stem cells using a mathematical model.
Topics: Aged; Aged, 80 and over; Cell Count; Cell Proliferation; Cell Survival; Confidence Intervals; Culture Media; Female; Glucose; Glutamic Acid; Glutamine; Humans; Kinetics; Lactic Acid; Male; Mesenchymal Stem Cells; Metabolic Networks and Pathways; Models, Biological; Tissue Donors | 2009 |
Charge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutamine.
Topics: Animals; Binding Sites; Cations; Dicarboxylic Acids; Gluconates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Ion Transport; Lactic Acid; Membrane Potentials; Models, Molecular; Mutation; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 2; Permeability; Protein Conformation; Rats; Structure-Activity Relationship; Tetraethylammonium; Xenopus laevis | 2009 |
Evolution of the neurochemical profile after transient focal cerebral ischemia in the mouse brain.
Topics: Animals; Aspartic Acid; Cerebrovascular Circulation; Corpus Striatum; Glucose; Glutamic Acid; Glutamine; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Metabolism; Mice | 2009 |
Glutamate is the major anaplerotic substrate in the tricarboxylic acid cycle of isolated rumen epithelial and duodenal mucosal cells from beef cattle.
Topics: Animals; Carbon Isotopes; Cattle; Citric Acid Cycle; Diet; Duodenum; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Glucose; Glutamic Acid; Glutamine; Intestinal Mucosa; Lactic Acid; Leucine; Male; Pyruvic Acid; Rumen; Valine | 2009 |
Prognostic value of proton magnetic resonance spectroscopy findings in near drowning patients: reversibility of the early metabolite abnormalities relates with a good outcome.
Topics: Child; Child, Preschool; Female; Glutamic Acid; Glutamine; Humans; Hypoxia-Ischemia, Brain; Lactic Acid; Lipid Metabolism; Magnetic Resonance Spectroscopy; Male; Near Drowning; Prognosis; Protons | 2009 |
Neurochemical changes in the rat prefrontal cortex following acute phencyclidine treatment: an in vivo localized (1)H MRS study.
Topics: Animals; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Overproduction of human interleukin-2 in recombinant Escherichia coli BL21 high-cell-density culture by the determination and optimization of essential amino acids using a simple stoichiometric model.
Topics: Acetate-CoA Ligase; Amino Acids, Essential; Bacteriological Techniques; Culture Media; Escherichia coli; Fermentation; Glucose; Glutamine; Humans; Interleukin-2; Kinetics; Lactic Acid; Models, Biological; Recombinant Proteins | 2009 |
Exchange-mediated dilution of brain lactate specific activity: implications for the origin of glutamate dilution and the contributions of glutamine dilution and other pathways.
Topics: Amino Acids; Animals; Astrocytes; Autoradiography; Blood Glucose; Brain Chemistry; Cortical Spreading Depression; Glutamic Acid; Glutamine; Lactic Acid; Oxidation-Reduction; Rats; Sensation | 2009 |
Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Edema; Brain Injuries; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Nerve Tissue Proteins; Neurotransmitter Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2009 |
Relationship between intracranial hemodynamics and microdialysis markers of energy metabolism and glutamate-glutamine turnover in patients with subarachnoid hemorrhage. Clinical article.
Topics: Aged; Biomarkers; Blood Pressure; Cerebrovascular Circulation; Critical Care; Energy Metabolism; Female; Glutamic Acid; Glutamine; Hemodynamics; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid; Retrospective Studies; Subarachnoid Hemorrhage | 2009 |
Pre-ischemic treatment with memantine reversed the neurochemical and behavioural parameters but not energy metabolites in middle cerebral artery occluded rats.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Brain; Glutamate-Ammonia Ligase; Glutamine; Glutathione; Lactic Acid; Male; Memantine; Middle Cerebral Artery; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2009 |
Porcine liver sinusoidal endothelial cells contribute significantly to intrahepatic ammonia metabolism.
Topics: Ammonia; Animals; Bioreactors; Endothelial Cells; Glutamic Acid; Glutaminase; Glutamine; Hepatocytes; Lactic Acid; Liver; Lysosomes; Male; Sus scrofa | 2009 |
CHO cells adhering to nitrogen-rich plasma-polymerised ethylene exhibit high production of a specific recombinant protein.
Topics: Animals; Cell Adhesion; CHO Cells; Coated Materials, Biocompatible; Cricetinae; Cricetulus; Ethylenes; Glucose; Glutamine; Integrin beta1; Lactic Acid; Materials Testing; Nitrogen; Polymers; Quaternary Ammonium Compounds; Recombinant Proteins; Surface Properties; Tissue Plasminogen Activator | 2009 |
The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study.
Topics: Acetates; Adolescent; Adult; Brain; Brain Chemistry; Brain Injuries; Citric Acid Cycle; Energy Metabolism; Female; Glucose; Glutamic Acid; Glutamine; Humans; Kinetics; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Microdialysis; Middle Aged; Young Adult | 2009 |
Glutamate metabolic pathways and retinal function.
Topics: Animals; Aspartate Aminotransferases; Electroretinography; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Homeostasis; Immunohistochemistry; Ketoglutaric Acids; Lactic Acid; Methionine Sulfoximine; Photoreceptor Cells, Vertebrate; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Succinic Acid; Synaptic Transmission; Vision, Ocular | 2009 |
Diffusion tensor imaging supports the cytotoxic origin of brain edema in a rat model of acute liver failure.
Topics: Ammonia; Animals; Astrocytes; Blood-Brain Barrier; Brain; Brain Edema; Diffusion Tensor Imaging; Glutamine; Lactic Acid; Liver Failure, Acute; Male; Permeability; Rats; Rats, Sprague-Dawley | 2010 |
Effects of glyoxal or methylglyoxal on the metabolism of amino acids, lactate, glucose and acetate in the cerebral cortex of young and adult rats.
Topics: Acetates; Aging; Amino Acids; Animals; Carbon Dioxide; Central Nervous System Agents; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glutamine; Glycine; Glyoxal; Lactic Acid; Lipid Metabolism; Male; Oxidation-Reduction; Protein Biosynthesis; Pyruvaldehyde; Rats; Rats, Wistar | 2010 |
Ex vivo expansion of human mesenchymal stem cells: a more effective cell proliferation kinetics and metabolism under hypoxia.
Topics: Ammonia; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Colony-Forming Units Assay; Glucose; Glutamine; Humans; Kinetics; Lactic Acid; Mesenchymal Stem Cells; Models, Biological; Oxygen; Phenotype | 2010 |
Protective effect of glutamine-enriched early enteral nutrition on intestinal mucosal barrier injury after liver transplantation in rats.
Topics: Animals; Bacterial Translocation; Biomarkers; Biopsy, Needle; Blotting, Western; Disease Models, Animal; Enteral Nutrition; Glutamine; Immunohistochemistry; Intestinal Diseases; Intestinal Mucosa; Lactic Acid; Liver Transplantation; Male; Malondialdehyde; Polymerase Chain Reaction; Postoperative Complications; Probability; Random Allocation; Rats; Rats, Wistar; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Metabolic alterations induced by ischemia in primary cultures of astrocytes: merging 13C NMR spectroscopy and metabolic flux analysis.
Topics: Adenosine Triphosphate; Amino Acids; Amino Acids, Branched-Chain; Animals; Astrocytes; Bioreactors; Brain Ischemia; Cell Death; Cell Hypoxia; Cell Survival; Cells, Cultured; Glucose; Glutamine; Glycolysis; L-Lactate Dehydrogenase; Lactic Acid; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Oxidative Phosphorylation; Pentose Phosphate Pathway; Rats; Rats, Sprague-Dawley | 2010 |
Investigations into the metabolism of two-dimensional colony and suspended microcarrier cultures of human embryonic stem cells in serum-free media.
Topics: Ammonia; Animals; Carbon; Cell Culture Techniques; Cell Line; Culture Media, Conditioned; Culture Media, Serum-Free; Embryonic Stem Cells; Glucose; Glutamine; Humans; Lactic Acid | 2010 |
Neurochemical changes in the developing rat hippocampus during prolonged hypoglycemia.
Topics: Animals; Animals, Newborn; Brain Chemistry; Chronic Disease; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glycolysis; Hippocampus; Homeostasis; Humans; Hypoglycemia; Infant Nutrition Disorders; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Neurons; Oxidative Phosphorylation; Phosphocreatine; Rats; Rats, Sprague-Dawley | 2010 |
Q&A: Cancer: clues from cell metabolism.
Topics: Adenosine Triphosphate; Animals; Cell Hypoxia; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycolysis; Lactic Acid; Metabolic Networks and Pathways; Neoplasms; Oxidative Phosphorylation; Oxygen | 2010 |
Single prolonged stress decreases glutamate, glutamine, and creatine concentrations in the rat medial prefrontal cortex.
Topics: Amygdala; Animals; Aspartic Acid; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hippocampus; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Stress, Psychological; Synaptic Transmission | 2010 |
Energetics of inhibition: insights with a computational model of the human GABAergic neuron-astrocyte cellular complex.
Topics: Adenosine Triphosphate; Astrocytes; Bayes Theorem; Cell Communication; Energy Metabolism; gamma-Aminobutyric Acid; Glutamine; Glycolysis; Homeostasis; Humans; Hydrolysis; Lactic Acid; Models, Neurological; Neurons; Oxidation-Reduction; Oxidative Phosphorylation; Protein Precursors | 2010 |
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Brain Chemistry; Cells, Cultured; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Immunohistochemistry; Lactic Acid; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Neurons; Nitrogen; Pyruvic Acid | 2011 |
Unraveling the metabolism of HEK-293 cells using lactate isotopomer analysis.
Topics: Acetyl Coenzyme A; Amino Acids; Carbon; Carbon Isotopes; Cell Line; Cell Survival; Chromatography, Liquid; Citric Acid Cycle; Glucose; Glutamine; HEK293 Cells; Humans; Lactic Acid; Lipids; Magnetic Resonance Spectroscopy; Malates; Oxaloacetic Acid; Pentose Phosphate Pathway | 2011 |
Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.
Topics: Amino Acid Motifs; Anaphase-Promoting Complex-Cyclosome; Cdh1 Proteins; Cell Cycle Proteins; G1 Phase; Glutaminase; Glutamine; Humans; Lactic Acid; Phosphofructokinase-2; S Phase; T-Lymphocytes; Ubiquitin-Protein Ligase Complexes | 2010 |
[Effect of oral glutamine on intestinal barrier function in young rats with endotoxemia].
Topics: Administration, Oral; Amine Oxidase (Copper-Containing); Animals; Behavior, Animal; Endotoxemia; Female; Glutamine; Intestinal Mucosa; Intestines; Lactic Acid; Male; Rats; Rats, Wistar | 2010 |
Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats.
Topics: Ammonia; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Cerebellum; Cerebrum; Encephalocele; Galactosamine; Glutamine; Intracranial Hypertension; Lactic Acid; Liver Failure, Acute; Male; Rats; Rats, Wistar | 2011 |
Estimation of intracellular fluxes in cerebellar neurons after hypoglycemia: importance of the pyruvate recycling pathway and glutamine oxidation.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Glucose; Glutamic Acid; Glutamine; Glycolysis; Hypoglycemia; Intracellular Fluid; Lactic Acid; Mice; Neural Pathways; Neurons; Oxidation-Reduction; Pyruvic Acid | 2011 |
Metabolic activity and monoclonal antibody production of Salmonella enteritidis O and H antigen specific hybridoma cells in static culture.
Topics: Ammonia; Antibodies, Monoclonal; Antigens, Bacterial; Cell Culture Techniques; Cell Line; Cell Survival; Culture Media; Glucose; Glutamine; Hybridomas; Kinetics; Lactic Acid; Salmonella enteritidis; Salmonella Infections | 2011 |
[2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells.
Topics: 3-Hydroxybutyric Acid; Animals; Aspartic Acid; Astrocytes; Brain Neoplasms; Citric Acid Cycle; Diet, Ketogenic; Glioblastoma; Glucose; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Mice; Tumor Cells, Cultured | 2011 |
Fetal and neonatal iron deficiency causes volume loss and alters the neurochemical profile of the adult rat hippocampus.
Topics: Anatomy, Cross-Sectional; Animals; Animals, Newborn; Creatine; Dipeptides; Female; Fetus; Glutamine; Hippocampus; Iron Deficiencies; Iron, Dietary; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Nerve Fibers, Myelinated; Neurochemistry; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Taurine; Time | 2011 |
Vigorous exercise increases brain lactate and Glx (glutamate+glutamine): a dynamic 1H-MRS study.
Topics: Adolescent; Adult; Brain; Brain Chemistry; Exercise; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Young Adult | 2011 |
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells.
Topics: Adenosine Triphosphate; Carcinoma; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Deoxyglucose; Disease Progression; Genes, p53; Glucose; Glutamine; Head and Neck Neoplasms; Humans; Lactic Acid; Mass Spectrometry; Metabolomics; Metformin; Neoplasms, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Suppressor Protein p53 | 2011 |
Photoperiodic regulation of glycogen metabolism, glycolysis, and glutamine synthesis in tanycytes of the Siberian hamster suggests novel roles of tanycytes in hypothalamic function.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Carbohydrate Metabolism; Cloning, Molecular; Cricetinae; DNA, Complementary; Ependyma; Glucose; Glutamic Acid; Glutamine; Glycogen; Glycolysis; Hypothalamus; In Situ Hybridization; Lactic Acid; Male; Microscopy, Electron; Neuropil; Phodopus; Photoperiod; Pyruvic Acid | 2011 |
Metabolic flux analysis gives an insight on verapamil induced changes in central metabolism of HL-1 cells.
Topics: Alanine; Animals; Calcium Channel Blockers; Carbon Isotopes; Cell Growth Processes; Cell Line; Cell Line, Tumor; Culture Media, Serum-Free; Glucose; Glutamic Acid; Glutamine; Glycolysis; Hydrogen-Ion Concentration; Lactic Acid; Metabolome; Mice; Myocytes, Cardiac; Oxygen; Verapamil | 2011 |
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia | 2012 |
Measuring multiple neurochemicals and related metabolites in blood and brain of the rhesus monkey by using dual microdialysis sampling and capillary hydrophilic interaction chromatography-mass spectrometry.
Topics: Acetylcholine; Animals; Blood Chemical Analysis; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macaca mulatta; Mass Spectrometry; Microdialysis; Pyruvic Acid | 2012 |
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.
Topics: Cell Line, Tumor; Citric Acid Cycle; Fermentation; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Glycolysis; Humans; Hypoxia; Ketoglutaric Acids; Lactic Acid; Melanocytes; Melanoma; Models, Biological; Skin Neoplasms | 2011 |
Conventional and advanced magnetic resonance imaging in tumefactive demyelination.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Contrast Media; Demyelinating Diseases; Diffusion Magnetic Resonance Imaging; Female; Follow-Up Studies; Gadolinium DTPA; Glutamic Acid; Glutamine; Humans; Image Enhancement; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multiple Sclerosis; Young Adult | 2011 |
Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Cell Line; Cell Survival; Citric Acid Cycle; Dose-Response Relationship, Drug; Doxorubicin; Energy Metabolism; Glucose; Glutamine; Glycolysis; Lactic Acid; Mice; Myocytes, Cardiac; Oxidation-Reduction; Pyruvic Acid; Time Factors | 2012 |
Rat brain slices oxidize glucose at high rates: a (13)C NMR study.
Topics: Acetates; Anesthesia; Anesthetics; Animals; Aspartic Acid; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2011 |
Comparative effects of short-term and long-term insulin-induced hypoglycemia on glucose production in the perfused livers of weaned rats.
Topics: Alanine; Animals; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoglycemia; Hypoglycemic Agents; Injections, Intraperitoneal; Insulin; Insulin Detemir; Insulin, Long-Acting; Lactic Acid; Liver; Male; Rats; Rats, Wistar; Time Factors | 2011 |
Effect of Conclevan on endurance capacity in mice.
Topics: Ammonia; Animals; Blood Glucose; Corticosterone; Fatigue; Glutamine; Lactic Acid; Liver; Male; Mice; Physical Endurance; Riboflavin; Swimming; Thiamine; Tissue Extracts; Urea; Vitamin B 12; Vitamin B 6; Vitamin B Complex | 2012 |
The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Transformation, Neoplastic; Citric Acid Cycle; DNA Primers; Glucokinase; Glucose; Glutamine; Humans; Immunoblotting; Immunohistochemistry; Isotope Labeling; Lactic Acid; Liver Neoplasms, Experimental; Lung Neoplasms; Metabolome; Mice; Nuclear Magnetic Resonance, Biomolecular; Proto-Oncogene Proteins c-met; Proto-Oncogene Proteins c-myc; RNA Interference | 2012 |
Evaluation of corpus geniculatum laterale and vitreous fluid by magnetic resonance spectroscopy in patients with glaucoma; a preliminary study.
Topics: Aged; Apoptosis; Aspartic Acid; Choline; Creatine; Female; Geniculate Bodies; Glaucoma, Open-Angle; Glutamic Acid; Glutamine; Gonioscopy; Humans; Intraocular Pressure; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Tonometry, Ocular; Vitreous Body | 2012 |
Improved expansion of human bone marrow-derived mesenchymal stem cells in microcarrier-based suspension culture.
Topics: Adipocytes; Ammonia; Bioreactors; Bone Marrow Cells; Cell Culture Techniques; Cell Differentiation; Cell Lineage; Cell Proliferation; Cells, Cultured; Glucose; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Mesenchymal Stem Cells; Osteoblasts; Stem Cells; Time Factors | 2014 |
The effect of fractionated plasma separation and adsorption on cerebral amino acid metabolism and oxidative metabolism during acute liver failure.
Topics: Adult; Amino Acids; Cerebrum; Dialysis Solutions; Extracorporeal Circulation; Female; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Male; Microdialysis; Middle Aged; Pyruvic Acid; Sorption Detoxification; Statistics, Nonparametric | 2012 |
Glutamine treatment decreases plasma and lymph cytotoxicity during sepsis in rats.
Topics: Animals; Blood; Blotting, Western; Cell Line; Cell Movement; Cell Survival; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Glutamine; HSP72 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; Lactic Acid; Lipopolysaccharides; Lymph; Macrophages; Male; Mesentery; Rats; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha | 2012 |
Metabolomic signatures in guinea pigs infected with epidemic-associated W-Beijing strains of Mycobacterium tuberculosis.
Topics: Acetates; Adenosine Monophosphate; Animals; Choline; Epidemics; Ethanolamine; Formates; Glutamic Acid; Glutamine; Guinea Pigs; Host-Pathogen Interactions; Lactic Acid; Lung; Magnetic Resonance Spectroscopy; Metabolome; Multivariate Analysis; Mycobacterium tuberculosis; Niacinamide; Phosphocreatine; Principal Component Analysis; ROC Curve; Tuberculoma; Tuberculosis, Pulmonary | 2012 |
Enhancement of spectral editing efficacy of multiple quantum filters in in vivo proton magnetic resonance spectroscopy.
Topics: Algorithms; Brain Chemistry; Citrates; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Phantoms, Imaging; Protons | 2012 |
Effects of glutamine treatment on myocardial damage and cardiac function in rats after severe burn injury.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Aspartate Aminotransferases; Biomarkers; Burns; Creatine Kinase, MB Form; Disease Models, Animal; Edema, Cardiac; Glutamine; Glutathione; Heart; Heart Diseases; Heart Function Tests; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Protective Agents; Rats; Rats, Wistar; Water | 2012 |
Substrate competition studies demonstrate oxidative metabolism of glucose, glutamate, glutamine, lactate and 3-hydroxybutyrate in cortical astrocytes from rat brain.
Topics: 3-Hydroxybutyric Acid; Astrocytes; Brain; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Oxidation-Reduction; Substrate Specificity | 2012 |
Aggravation of cyclophosphamide-induced acute neurological disorders under conditions of artificial acidification of chyme in rats.
Topics: Acute Disease; Administration, Oral; Ammonia; Animals; Boric Acids; Cyclophosphamide; Gastric Juice; Gastric Mucosa; Glutamine; Hydrochloric Acid; Hydrogen-Ion Concentration; Hyperammonemia; Lactic Acid; Male; Neurotoxicity Syndromes; Rats; Stomach; Sulfuric Acids; Survival Rate; Urea | 2012 |
Inhibitory effect of tumor necrosis factor α on gluconeogenesis in perfused rat liver.
Topics: Alanine; Animals; Area Under Curve; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Urea | 2013 |
A naonoporous cell-therapy device with controllable biodegradation for long-term drug release.
Topics: Alginates; Animals; Cell Transplantation; Delayed-Action Preparations; Dopamine; Equipment Design; Glucuronic Acid; Glutamine; Hexuronic Acids; Lactic Acid; Mice; Mice, Inbred BALB C; Nanostructures; Nerve Growth Factor; PC12 Cells; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polylysine; Porosity; Rats | 2013 |
Metabolomic analysis of cerebrospinal fluid indicates iron deficiency compromises cerebral energy metabolism in the infant monkey.
Topics: Anemia, Iron-Deficiency; Animals; Brain; Citric Acid; Energy Metabolism; Female; Glutamine; Iron Deficiencies; Lactic Acid; Macaca mulatta; Magnetic Resonance Imaging; Metabolomics; Pyruvic Acid | 2013 |
Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Basic Helix-Loop-Helix Transcription Factors; Bone Resorption; Cell Hypoxia; Cell Survival; Cells, Cultured; Electron Transport Chain Complex Proteins; Energy Metabolism; Glucose; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Mitochondria; Osteoclasts; Oxygen Consumption; Pyruvate Dehydrogenase Complex; RNA Interference; Time Factors; Transfection; Up-Regulation | 2013 |
Metabolomic profilings of urine and serum from high fat-fed rats via 1H NMR spectroscopy and pattern recognition.
Topics: 3-Hydroxybutyric Acid; Animals; Choline; Citric Acid; Creatinine; Diabetes Mellitus, Type 2; Dietary Fats; Glutamic Acid; Glutamine; Hippurates; Lactic Acid; Magnetic Resonance Spectroscopy; Metabolomics; Obesity; Rats; Taurine | 2013 |
Abnormal activity-dependent brain lactate and glutamate+glutamine responses in panic disorder.
Topics: Adult; Analysis of Variance; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Photic Stimulation; Somatoform Disorders; Tritium; Visual Cortex | 2013 |
Assessment of brain metabolites change during visual sexual stimulation in healthy women using functional MR spectroscopy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Erotica; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Libido; Lipid Metabolism; Magnetic Resonance Spectroscopy; Middle Aged; Photic Stimulation; Sexual Behavior; Young Adult | 2013 |
Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Glutamine; Glycolysis; Hexosamines; Humans; Hypoxia; Lactic Acid; Male; Metabolic Networks and Pathways; Mice; Mice, Nude; Mice, Transgenic; Models, Biological; Pancreatic Neoplasms; Transplantation, Heterologous | 2013 |
Cancer control via glucose and glutamine deprivation.
Topics: Endothelium, Vascular; Glucose; Glutamine; Humans; Lactic Acid; Neoplasms; Neovascularization, Pathologic | 2013 |
Left ventricular assist device effects on metabolic substrates in the failing heart.
Topics: Adult; Alanine; Amino Acids, Aromatic; Case-Control Studies; Creatine; Female; Glucose; Glutamine; Heart Failure; Heart-Assist Devices; Humans; Lactic Acid; Male; Middle Aged; Myocardium; Succinic Acid | 2013 |
Cerebral microdialysis reflects the neuroprotective effect of fractionated plasma separation and adsorption in acute liver failure better and earlier than intracranial pressure: a controlled study in pigs.
Topics: Ammonia; Animals; Brain Edema; Cerebrum; Extracorporeal Circulation; Glucose; Glutamic Acid; Glutamine; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Microdialysis; Pyruvic Acid; Sorption Detoxification; Swine; Time Factors | 2013 |
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.
Topics: Acetates; Cell Hypoxia; Cell Line, Tumor; Cells; Citric Acid; Citric Acid Cycle; Fatty Acids; Glutamine; Humans; Ketoglutaric Acids; Lactic Acid; Models, Biological; NAD; Nicotinamide Mononucleotide; Oxidation-Reduction; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase | 2013 |
Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective.
Topics: Astrocytes; Brain; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Models, Biological; Neurons; Oxidation-Reduction; Reproducibility of Results; Synaptic Transmission | 2013 |
Investigation of growth conditions for the expansion of porcine mesenchymal stem cells on microcarriers in stirred cultures.
Topics: Ammonia; Animals; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Culture Media; Glucose; Glutamine; Kinetics; Lactic Acid; Mesenchymal Stem Cells; Microspheres; Multipotent Stem Cells; Sus scrofa | 2014 |
Enzymatic production and degradation of cheese-derived non-proteolytic aminoacyl derivatives.
Topics: Carboxypeptidases; Cheese; Chymotrypsin; Dipeptides; gamma-Glutamyltransferase; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Pepsin A; Phenylalanine; Proteolysis; Trypsin | 2014 |
Rapid uptake of glucose and lactate, and not hypoxia, induces apoptosis in three-dimensional tumor tissue culture.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Humans; Hypoxia; Kinetics; Lactic Acid; Microscopy, Fluorescence; Models, Theoretical | 2014 |
Increased brain lactate is central to the development of brain edema in rats with chronic liver disease.
Topics: Ammonia; Animals; Brain; Brain Edema; Chronic Disease; Glutamine; Hepatic Encephalopathy; Lactic Acid; Liver Diseases; Male; Rats; Rats, Sprague-Dawley | 2014 |
Optimization and robustness analysis of hybridoma cell fed-batch cultures using the overflow metabolism model.
Topics: Ammonia; Animals; Cell Culture Techniques; Glucose; Glutamine; Hybridomas; Lactic Acid; Mice; Models, Biological; Oxygen Consumption | 2014 |
Serum 1H-NMR metabolomic fingerprints of acute-on-chronic liver failure in intensive care unit patients with alcoholic cirrhosis.
Topics: Biomarkers; Creatinine; Glutamine; Humans; Intensive Care Units; Ketone Bodies; Lactic Acid; Liver Cirrhosis, Alcoholic; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Metabolome; Multivariate Analysis; Phenylalanine; Pyruvic Acid; Tyrosine | 2014 |
Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes.
Topics: Adenylate Kinase; Cell Line, Tumor; Cell Proliferation; Gene Knockdown Techniques; Glucose; Glutamine; Humans; In Vitro Techniques; Lactic Acid; Mouth Neoplasms; RNA, Small Interfering; Secondary Metabolism; Transketolase | 2014 |
Neurobehaviour between birth and 40 weeks' gestation in infants born <30 weeks' gestation and parental psychological wellbeing: predictors of brain development and child outcomes.
Topics: Aspartic Acid; Biomarkers; Brain; Case-Control Studies; Child Development; Choline; Gestational Age; Glutamic Acid; Glutamine; Humans; Infant, Newborn; Infant, Premature; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mental Health; Neurologic Examination; Neuropsychological Tests; Parent-Child Relations; Parenting; Parents; Premature Birth; Prospective Studies; Term Birth | 2014 |
Adaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells.
Topics: Animals; Carrier Proteins; Cell Line; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Energy Metabolism; Glucose; Glutamine; Humans; Intracellular Signaling Peptides and Proteins; Lactic Acid; Membrane Glycoproteins; Mitochondria; Niemann-Pick C1 Protein; RNA Interference | 2014 |
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.
Topics: Adult; Aged; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain; Brain Neoplasms; Female; Glioblastoma; Glutamine; Glutathione; Glycolysis; Humans; L-Lactate Dehydrogenase; Lactic Acid; Male; Mice, SCID; Mice, Transgenic; Middle Aged; Neoplasm Transplantation; Oxidative Stress; Radionuclide Imaging; Rats, Nude | 2015 |
Brain energy metabolism measured by (13)C magnetic resonance spectroscopy in vivo upon infusion of [3-(13)C]lactate.
Topics: Animals; Blood Gas Analysis; Brain; Carbon Isotopes; Energy Metabolism; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Radionuclide Imaging; Rats; Rats, Sprague-Dawley | 2015 |
NADH-linked metabolic plasticity of MCF-7 breast cancer cells surviving in a nutrient-deprived microenvironment.
Topics: Female; Glutamine; Glycolysis; Humans; Lactic Acid; MCF-7 Cells; NAD; Starvation; Tumor Microenvironment | 2015 |
Precursors of hexoneogenesis within the human mammary gland.
Topics: Adult; Blood Glucose; Breast Feeding; Carbon Isotopes; Female; Galactose; Gluconeogenesis; Glucose; Glutamine; Glycerol; Humans; Infusions, Intravenous; Lactation; Lactic Acid; Lactose; Mammary Glands, Human; Milk, Human; Pentose Phosphate Pathway; Sodium Acetate; Texas | 2015 |
Exploring continuous and integrated strategies for the up- and downstream processing of human mesenchymal stem cells.
Topics: Ammonia; Bioreactors; Cell Adhesion; Cell Count; Cell Culture Techniques; Cell Proliferation; Cell Survival; Fibroblasts; Foreskin; Glucose; Glutamine; Humans; Lactic Acid; Male; Mesenchymal Stem Cells; Perfusion; Telomerase | 2015 |
Nutrient depletion and metabolic profiles in breast carcinoma cell lines measured with a label-free platform.
Topics: Actins; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Cytochalasin B; Glucose; Glucose Transporter Type 1; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; MCF-7 Cells; Metabolome; Oxazines; Oxygen; RNA, Messenger; Xanthenes | 2015 |
Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway.
Topics: Adenosine Triphosphate; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Female; Glucose; Glutamine; Humans; Lactic Acid; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; TOR Serine-Threonine Kinases | 2015 |
Stanniocalcin 1 effects on the renal gluconeogenesis pathway in rat and fish.
Topics: Animals; Bass; Fish Proteins; Gene Expression Regulation; Gluconeogenesis; Glutamine; Glycoproteins; Humans; Intracellular Signaling Peptides and Proteins; Kidney Cortex; Kidney Medulla; Lactic Acid; Male; Mammals; Mitochondria; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar | 2015 |
Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression.
Topics: Amino Acid Transport System ASC; Animals; beta Catenin; Caco-2 Cells; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucose; Glutaminase; Glutamine; Glycolysis; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Lactic Acid; Male; Mice, Nude; Middle Aged; Minor Histocompatibility Antigens; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; Time Factors; Transcription, Genetic; Transfection; Tumor Burden; Tumor Suppressor Proteins | 2015 |
Influence of Serum and Hypoxia on Incorporation of [(14)C]-D-Glucose or [(14)C]-L-Glutamine into Lipids and Lactate in Murine Glioblastoma Cells.
Topics: Animals; Carbon Radioisotopes; Cattle; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cholesterol; Fatty Acids; Gangliosides; Glioblastoma; Glucose; Glutamine; Lactic Acid; Lipid Metabolism; Male; Mice; Neoplasm Transplantation; Phospholipids; Serum; Triglycerides | 2015 |
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Glutaminase; Glutamine; HeLa Cells; Humans; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Monocarboxylic Acid Transporters; Neoplasms; Oxidation-Reduction; Symporters | 2016 |
Responses of CHO cell lines to increased pCO2 at normal (37 °C) and reduced (33 °C) culture temperatures.
Topics: Animals; Carbon Dioxide; Cell Proliferation; Cell Survival; CHO Cells; Cricetulus; Gene Expression Regulation; Glucose; Glutamine; Lactic Acid; Proteome; Proteomics; Temperature | 2016 |
Catabolism of Branched Chain Amino Acids Contributes Significantly to Synthesis of Odd-Chain and Even-Chain Fatty Acids in 3T3-L1 Adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Amino Acids, Branched-Chain; Animals; Carbon Isotopes; Cell Differentiation; Cell Proliferation; Fatty Acids; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Kinetics; Lactic Acid; Metabolic Networks and Pathways; Mice | 2015 |
Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism.
Topics: Animals; Cell Death; Cells, Cultured; Glucose; Glutamine; Lactic Acid; Neurons; Percussion; Rats; Rats, Sprague-Dawley | 2016 |
Metabolic analysis of antibody producing Chinese hamster ovary cell culture under different stresses conditions.
Topics: Animals; Antibody Formation; Cell Proliferation; Cell Survival; CHO Cells; Cluster Analysis; Cricetinae; Cricetulus; Glucose; Glutamine; Lactic Acid; Metabolome; Metabolomics; Principal Component Analysis; Protein Processing, Post-Translational; Sodium Chloride; Time Factors; Trehalose | 2016 |
Capillary electrophoresis for automated on-line monitoring of suspension cultures: Correlating cell density, nutrients and metabolites in near real-time.
Topics: Bioreactors; Cell Count; Cell Culture Techniques; Culture Media; Electrophoresis, Capillary; Glucose; Glutamine; Humans; Jurkat Cells; Lactic Acid | 2016 |
Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling.
Topics: Angiogenesis Inhibitors; Animals; Axitinib; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Glycolysis; Humans; Imidazoles; Indazoles; Indoles; Intestinal Neoplasms; Lactic Acid; Membrane Transport Proteins; Mice; Models, Biological; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Signal Transduction; Sirolimus; Stomach Neoplasms; Sunitinib; TOR Serine-Threonine Kinases; Up-Regulation | 2016 |
The Metabolic Responses to L-Glutamine of Livers from Rats with Diabetes Types 1 and 2.
Topics: Alanine; Ammonia; Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gluconeogenesis; Glucose; Glutamine; Glycogen; Lactic Acid; Liver; Male; Oxygen; Rats; Rats, Wistar; Urea | 2016 |
Glucose, Lactate and Glutamine but not Glutamate Support Depolarization-Induced Increased Respiration in Isolated Nerve Terminals.
Topics: Animals; Antimycin A; Brain; Cell Respiration; Glucose; Glutamic Acid; Glutamine; Lactic Acid; Mice; Presynaptic Terminals; Rotenone | 2017 |
Metabolic abnormality in the right dorsolateral prefrontal cortex in patients with obsessive-compulsive disorder: proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Male; Neuroimaging; Obsessive-Compulsive Disorder; Prefrontal Cortex; Proton Magnetic Resonance Spectroscopy; Young Adult | 2017 |
Bioluminescent Assays for Glucose and Glutamine Metabolism: High-Throughput Screening for Changes in Extracellular and Intracellular Metabolites.
Topics: Cell Line, Tumor; Female; Glucose; Glutamic Acid; Glutamine; Glycolysis; High-Throughput Screening Assays; Humans; Lactic Acid; Luminescent Measurements; Ovary; Sensitivity and Specificity | 2017 |
Diagnosing necrotic meningioma: a distinctive imaging pattern in diffusion MRI and MR spectroscopy.
Topics: Choline; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Necrosis; Tritium | 2017 |
Glucose, Lactate, β-Hydroxybutyrate, Acetate, GABA, and Succinate as Substrates for Synthesis of Glutamate and GABA in the Glutamine-Glutamate/GABA Cycle.
Topics: 3-Hydroxybutyric Acid; Acetates; Animals; Astrocytes; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Lactic Acid; Neurons; Succinates | 2016 |
Altering the central carbon metabolism of HEK293 cells: Impact on recombinant glycoprotein quality.
Topics: Ammonia; Bioreactors; Carbon; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Glucose; Glutamine; Glycoproteins; Glycosylation; HEK293 Cells; Humans; Interferon alpha-2; Interferon-alpha; Lactic Acid; Metabolic Engineering; Pyruvate Carboxylase; Recombinant Proteins; Yeasts | 2017 |
Magnetic Resonance Spectroscopy for Evaluating Portal-Systemic Encephalopathy in Patients with Chronic Hepatic Schistosomiasis Japonicum.
Topics: Aged; Aged, 80 and over; Ammonia; Brain; Chronic Disease; Female; Globus Pallidus; Glutamine; Hepatic Encephalopathy; Humans; Lactic Acid; Liver Diseases; Liver Function Tests; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schistosomiasis japonica | 2016 |
Clinical Factors Associated with Cerebral Metabolism in Term Neonates with Congenital Heart Disease.
Topics: Aspartic Acid; Biomarkers; Birth Weight; Brain; Cohort Studies; Female; Gestational Age; Glutamine; Heart Defects, Congenital; Humans; Infant, Newborn; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Monitoring, Intraoperative; Multivariate Analysis; Phosphocreatine; Preoperative Care; Prognosis; Prospective Studies; Regression Analysis; Risk Assessment; Survival Rate; Term Birth; Treatment Outcome | 2017 |
Metabolic Characterization of Myocardial Infarction Using GC-MS-Based Tissue Metabolomics.
Topics: Animals; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Lactic Acid; Male; Metabolomics; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2017 |
Metabolic engineering of CHO cells for the development of a robust protein production platform.
Topics: Animals; Antibodies, Monoclonal; Bioreactors; Carbon; CHO Cells; Citric Acid Cycle; Cricetinae; Cricetulus; Cytoplasm; Cytosol; Energy Metabolism; Gene Dosage; Glucose; Glutamine; Glycosylation; Lactates; Lactic Acid; Metabolic Engineering; Mitochondria; Oligonucleotides; Oxidation-Reduction; Polysaccharides; Pyruvate Carboxylase; Pyruvic Acid; Saccharomyces cerevisiae | 2017 |
Real-time monitoring system for evaluating the acid-producing activity of oral squamous cell carcinoma cells at different environmental pH.
Topics: Acids; Ammonia; Antimetabolites; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Deoxyglucose; Glucose; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Monitoring, Physiologic; Mouth Neoplasms | 2017 |
A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect.
Topics: Animals; Cell Proliferation; Computer Simulation; Glucose; Glutamine; Humans; Lactic Acid; Metabolic Flux Analysis; Metabolic Networks and Pathways; Models, Biological; Neoplasms | 2017 |
Glucose feeds the TCA cycle via circulating lactate.
Topics: Animals; Blood Glucose; Brain; Carbon; Citric Acid Cycle; Fasting; Glucose; Glutamine; Glycolysis; Lactic Acid; Mice; Muscles; Pancreatic Neoplasms | 2017 |
Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells.
Topics: Acetazolamide; Animals; Antimanic Agents; Aquaporin 2; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line; Deoxyglucose; Diabetes Insipidus, Nephrogenic; Epithelial Sodium Channels; Female; Glutamine; Glycolysis; Kidney Tubules, Collecting; Lactic Acid; Lithium Chloride; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2018 |
Impact of real-time metabolomics in liver transplantation: Graft evaluation and donor-recipient matching.
Topics: Adult; Aged; Aged, 80 and over; Female; Glutamine; Humans; Lactic Acid; Liver Transplantation; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phospholipids; Tissue Donors; Transplantation, Homologous | 2018 |
Concomitant reduction of lactate and ammonia accumulation in fed-batch cultures: Impact on glycoprotein production and quality.
Topics: Ammonia; Animals; Batch Cell Culture Techniques; Bioreactors; CHO Cells; Cricetinae; Cricetulus; Culture Media; Glucose; Glutamine; Glycoproteins; HEK293 Cells; Humans; Lactic Acid; Recombinant Proteins | 2018 |
Glutamine-derived 2-hydroxyglutarate is associated with disease progression in plasma cell malignancies.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Citric Acid Cycle; Disease Progression; DNA-Binding Proteins; Glucose; Glutamine; Glutarates; Glycolysis; Humans; Lactic Acid; Multiple Myeloma; Multivariate Analysis; Neoplasms; Plasma Cells; Transcription Factors | 2018 |
The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells.
Topics: A549 Cells; Animals; Glucose; Glutamine; Glycerol; Heterografts; Humans; Lactic Acid; Male; Mice; Mice, Nude; Neoplasms; Phosphoenolpyruvate Carboxykinase (ATP); Phospholipids | 2018 |
Changes in Brain Metabolite Concentrations after Neonatal Hypoxic-ischemic Encephalopathy.
Topics: Aspartic Acid; Creatine; Female; Glutamic Acid; Glutamine; Gray Matter; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Patient Outcome Assessment; Predictive Value of Tests; Retrospective Studies | 2018 |
Metabolic Characterization of Peripheral Host Responses to Drainage-Resistant Klebsiella pneumoniae Liver Abscesses by Serum 1H-NMR Spectroscopy.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Alanine; Amino Acids; Blood Glucose; Drug Resistance, Multiple, Bacterial; Female; Glutamine; Humans; Image Cytometry; Klebsiella Infections; Klebsiella pneumoniae; Lactic Acid; Liver Abscess; Lymphocyte Subsets; Male; Metabolome; Metabolomics; Middle Aged; Paracentesis; Proton Magnetic Resonance Spectroscopy | 2018 |
Glucose and glutamine handling in the Sertoli cells of transgenic rats overexpressing regucalcin: plasticity towards lactate production.
Topics: Animals; Apoptosis; Calcium-Binding Proteins; Cells, Cultured; Glucose; Glucose Transporter Type 2; Glutamine; Infertility, Male; Lactic Acid; Male; Phosphofructokinase-1; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Seminiferous Tubules; Sertoli Cells; Spermatogenesis | 2018 |
Comparative phenotypic analysis of CHO clones and culture media for lactate shift.
Topics: Alanine; Animals; Aspartic Acid; Cell Culture Techniques; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Culture Media; Glutamine; Lactic Acid; Metabolic Networks and Pathways; Phenotype; Serine | 2018 |
Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors.
Topics: Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Glucose; Glutamine; Glycolysis; Humans; Kinetics; Lactic Acid; Metabolic Networks and Pathways; Metabolome; Neoplasms; Oxygen; Tumor Microenvironment | 2018 |
Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia.
Topics: Acetyl Coenzyme A; Ammonia; Animals; Carbon; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glucose; Glutamine; HEK293 Cells; Humans; Lactic Acid; Lipogenesis; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Nude; Neoplasms; Nitrogen; Nucleotides; Orotic Acid; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2019 |
High extracellular lactate causes reductive carboxylation in breast tissue cell lines grown under normoxic conditions.
Topics: Amino Acids; Breast Neoplasms; Carbon Isotopes; Cell Culture Techniques; Cell Line, Tumor; Citric Acid; Citric Acid Cycle; Glutamine; Glycolysis; Humans; Lactic Acid; Metabolic Flux Analysis; Oxidation-Reduction | 2019 |
Highly Glycolytic Immortalized Human Dermal Microvascular Endothelial Cells are Able to Grow in Glucose-Starved Conditions.
Topics: Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Extracellular Space; Gene Expression Regulation; Glucose; Glutamine; Glycolysis; Humans; Lactic Acid; Microvessels; Monocarboxylic Acid Transporters; Oxygen Consumption; Skin; Symporters | 2019 |
Multifunctional Regulation of 3D Cell-Laden Microsphere Culture on an Integrated Microfluidic Device.
Topics: Calcium; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Coculture Techniques; Edetic Acid; Equipment Design; Glutamine; Human Umbilical Vein Endothelial Cells; Humans; Hydrogels; Lab-On-A-Chip Devices; Lactic Acid; Microspheres; Vascular Endothelial Growth Factor A | 2019 |
Development of a Model to Test Whether Glycogenolysis Can Support Astrocytic Energy Demands of Na
Topics: Astrocytes; Energy Metabolism; Glucose; Glutamine; Glycogenolysis; Lactic Acid; Models, Biological; Neurons; Sodium-Potassium-Exchanging ATPase | 2019 |
Topics: Animals; Brain; Brain Mapping; Cell Line, Tumor; Diagnostic Imaging; gamma-Aminobutyric Acid; Glioblastoma; Glioma; Glucose; Glutamic Acid; Glutamine; Glycolysis; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Staining and Labeling | 2020 |
Are there differences in the biochemical profile of bilateral normal testes? A 3.0 T 1H-MR spectroscopy study.
Topics: Adolescent; Adult; Creatine; Glutamic Acid; Glutamine; Humans; Lactic Acid; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Retrospective Studies; Testis; Young Adult | 2020 |
Combining lipoic acid to methylene blue reduces the Warburg effect in CHO cells: From TCA cycle activation to enhancing monoclonal antibody production.
Topics: Animals; Antibodies, Monoclonal; Cell Proliferation; Cell Survival; CHO Cells; Citric Acid Cycle; Cricetulus; Glucose; Glutamine; Glycolysis; Lactic Acid; Membrane Potential, Mitochondrial; Metabolic Engineering; Methylene Blue; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Respiration; Thioctic Acid | 2020 |
Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging.
Topics: Adenocarcinoma of Lung; Citric Acid; Glutamine; Humans; Lactic Acid; Lung Neoplasms; Multimodal Imaging; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured | 2020 |
Time-resolved non-invasive metabolomic monitoring of a single cancer spheroid by microfluidic NMR.
Topics: Alanine; Glucose; Glutamine; Humans; Hydrogen-Ion Concentration; Lab-On-A-Chip Devices; Lactic Acid; Magnetic Resonance Spectroscopy; MCF-7 Cells; Metabolomics; Microfluidic Analytical Techniques; Neoplasms; Spheroids, Cellular | 2021 |
Glutaminolysis is a metabolic route essential for survival and growth of prostate cancer cells and a target of 5α-dihydrotestosterone regulation.
Topics: Amino Acid Transport System ASC; Androgens; Anilides; Animals; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Glucose; Glutaminase; Glutamine; Glycolysis; Humans; Lactic Acid; Lipid Metabolism; Male; Minor Histocompatibility Antigens; Models, Biological; Neoplasm Proteins; Nitriles; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rats; Sulfides; Thiadiazoles; Tosyl Compounds | 2021 |
Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for hypercholesterolemia.
Topics: Adolescent; Adult; Arginine; Biomarkers; Case-Control Studies; Cholesterol; Cysteine; Female; Gas Chromatography-Mass Spectrometry; Glucose; Glutamine; Humans; Hypercholesterolemia; Lactic Acid; Lysine; Male; Metabolomics; Methionine; Middle Aged; Phosphoric Acids; Urea; Young Adult | 2021 |
Differential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells.
Topics: Animals; Breast; Breast Neoplasms; Carcinogenesis; Cell Proliferation; Epidermal Growth Factor; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Glutamic Acid; Glutamine; Humans; Lactic Acid; Mammary Glands, Human; Proto-Oncogene Proteins p21(ras); Tumor Cells, Cultured | 2021 |
Topics: Animals; Brain; Carbon-13 Magnetic Resonance Spectroscopy; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Lactic Acid; Male; Metabolome; Myocardium; Pentose Phosphate Pathway; Rats, Sprague-Dawley | 2021 |
Metabolic abnormality in acute stroke-like lesion and its relationship with focal cerebral blood flow in patients with MELAS: Evidence from proton MR spectroscopy and arterial spin labeling.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Male; MELAS Syndrome; Metabolomics; Middle Aged; Prospective Studies; Proton Magnetic Resonance Spectroscopy; Spin Labels; Young Adult | 2021 |
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Topics: Animals; Glucose; Glutamine; Lactic Acid; Mice; NADP; Neoplasms; Pentose Phosphate Pathway | 2021 |
Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment.
Topics: Animals; Cancer-Associated Fibroblasts; Cell Line; Citric Acid Cycle; Collagen; Disease Susceptibility; Enzyme Activation; Fibrosis; Gene Expression Regulation, Enzymologic; Glutamine; Humans; Lactic Acid; Mice; Neoplasms; Protein Biosynthesis; Pyruvate Carboxylase; Transforming Growth Factor beta; Tumor Microenvironment | 2021 |
A biomimetic ZIF nanoagent for synergistic regulation of glutamine metabolism and intracellular acidosis of cancer.
Topics: Animals; Biomimetic Materials; Cell Survival; Enzyme Inhibitors; Glutamine; Humans; Imidazoles; Lactic Acid; MCF-7 Cells; Nanoparticles; Neoplasms; Sulfides; Thiadiazoles; Zeolites | 2022 |
Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions.
Topics: Cell Line, Tumor; Cell Proliferation; Culture Media; Glucose; Glutamine; HeLa Cells; Humans; Lactic Acid; Metabolomics; Metformin; NAD; Oxygen; Pyruvic Acid; Tumor Hypoxia | 2022 |
Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics.
Topics: 3-Hydroxybutyric Acid; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Imaging; Reproducibility of Results; Synaptic Transmission | 2022 |
Elevated glutamate and decreased glutamine levels in the cerebrospinal fluid of patients with MELAS syndrome.
Topics: Adult; Alanine; Case-Control Studies; DNA, Mitochondrial; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Male; MELAS Syndrome; Middle Aged; Stroke | 2022 |
Attenuation of glutamine synthetase selection marker improves product titer and reduces glutamine overflow in Chinese hamster ovary cells.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Glutamate-Ammonia Ligase; Glutamine; Immunoglobulin G; Lactic Acid; Methionine Sulfoximine | 2022 |
Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses.
Topics: Cells, Cultured; Fibroblasts; Glutamic Acid; Glutamine; Humans; Lactic Acid; Obesity; Osteoarthritis, Hip; Synovial Fluid; Synovial Membrane; Tumor Necrosis Factor-alpha | 2022 |
Monitoring Training Load, Immune-Endocrine, Autonomic Nervous System Responses, and Swimming Performance in Women's Water Polo.
Topics: Autonomic Nervous System; Female; Glutamine; Hormones; Humans; Immunoglobulin A, Secretory; Lactic Acid; Physical Exertion; Swimming; Water Sports | 2023 |
TGF-β3 induces lactate production in Sertoli cell through inhibiting the Notch pathway.
Topics: Adenosine Triphosphate; Animals; Esters; Glucose; Glutaminase; Glutamine; L-Lactate Dehydrogenase; Lactic Acid; Male; p38 Mitogen-Activated Protein Kinases; Phosphofructokinases; Proto-Oncogene Proteins c-akt; Rats; RNA, Small Interfering; Sertoli Cells; Transforming Growth Factor beta3; Transforming Growth Factors | 2022 |
Adaptive responses in uteroplacental metabolism and fetoplacental nutrient shuttling and sensing during placental insufficiency.
Topics: Amino Acids; AMP-Activated Protein Kinases; Animals; Female; Fetal Growth Retardation; Fetus; Glucose; Glutamine; Glycine; Humans; Lactic Acid; Nutrients; Oxygen; Placenta; Placental Insufficiency; Pregnancy; Pyruvates; Serine; Sheep | 2023 |
Neurometabolic changes in a rat pup model of type C hepatic encephalopathy depend on age at liver disease onset.
Topics: Adult; Animals; Brain; Child; Glutamine; Hepatic Encephalopathy; Humans; Lactic Acid; Liver Diseases; Magnetic Resonance Spectroscopy; Rats | 2023 |
Interleukin 6 acutely increases gluconeogenesis and decreases the suppressive effect of insulin on cAMP-stimulated glycogenolysis in rat liver.
Topics: Alanine; Animals; Blood Glucose; Gluconeogenesis; Glucose; Glutamine; Glycogen; Glycogenolysis; Insulin; Insulin Resistance; Interleukin-6; Lactic Acid; Liver; Pyruvates; Rats | 2023 |
The interaction of ammonia and manganese in abnormal metabolism of minimal hepatic encephalopathy: A comparison metabolomics study.
Topics: Alanine; Ammonia; Animals; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Hyperammonemia; Inositol; Isoleucine; Lactic Acid; Leucine; Manganese; Metabolomics; Rats; Rats, Sprague-Dawley; Taurine | 2023 |